Digital Commons Network^™

The Truth Effect And Divided Attention By Picture Memorization, Aedan D. Erickson, Caitlin G. Tjeerdsma, Jacob D. Ostergard

Student Work

The truth effect examines an individual’s likelihood to believe new information with repeated exposure. This study analyzed the effects of a secondary memorization-distraction task on the truth effect and whether familiarity with the subject matter increases the impact of the truth effect. We recruited 95 undergraduate, college students to view a slideshow containing four trivia statements under conditions of repeated or single exposure and assignment or no assignment of a secondary memorization-distraction task. The results showed no effect of a secondary memorization-distraction task on the truth effect and no relationship between repeated exposure and validity scores. Participants’ familiarity of subject …

Icc Agenda 12-16-25, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Approved Courses 12-16-25, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Governance & Guardrails: Artificial Intelligence And Low-Wage Workers, Seema N. Patel

Maryland Law Review

No abstract provided.

Social Murder And The Antisocial Contract, Marissa Jackson Sow

Maryland Law Review

No abstract provided.

Generality And Abusive Constitutionalism, Ofra Bloch

Maryland Law Review

No abstract provided.

Caste As Practice, Analogy, And Metaphor, Mark A. Graber

Maryland Law Review

No abstract provided.

Caste And American Citizenship In The Trump Era, Carol Nackenoff

Maryland Law Review

No abstract provided.

How Ai Reinforces Caste: Creating And Amplifying Systematic Inequality, Catherine Powell

Maryland Law Review

No abstract provided.

Under What Circumstances Is “Caste” Likely To Be Useful As An Analytic Concept (And Should We Care)?, Sanford Levinson, Robert L. Tsai

Maryland Law Review

No abstract provided.

No Return: Caste And The End Of The Liberal Debate Over U.S. Antidiscrimination Law, Julie Novkov

Maryland Law Review

No abstract provided.

Attitudes Driving Regional Differences In Long-Acting Injectable Antipsychotic Utilization For Schizophrenia Among Healthcare Professionals, Patients, And Caregivers (Advance): Results From A Multinational Survey Study, Martha Sajatovic

Faculty Scholarship

Background: Long-acting injectable (LAI) antipsychotics improve adherence and reduce schizophrenia relapse rates vs oral antipsychotics (OAs) but remain underused. The ADVANCE study explored country-level differences in LAI use among healthcare professionals (HCPs), patients, and caregivers, to identify drivers of LAI use. Study Design: ADVANCE included participants from Australia, Canada, China, Germany, Israel, South Korea, Spain, and the United States. Eligible HCPs spent ≥25% of their time in direct patient care, managed an adult population of whom ≥10% have schizophrenia, and treated patients prescribed LAIs. Patients aged ≥18 years and caregivers of adults living with schizophrenia who had tried/been offered an …

Robotic Anatomical Left Hepatectomy With Enbloc Caudate Resection For Intrahepatic Cholangiocarcinoma, Bhavya Bansal, Parisa Yazdankhah-Kenary, Sharona Ross, Iswanto Sucandy

Student Papers, Posters & Projects

Introduction: Minimally invasive robotic technique is gaining popularity due to its technical advantages when compared with conventional laparoscopy. Major hepatic lobectomy, however, remains a technically demanding procedure and requires extensive training to ensure safety and efficacy, especially when undertaken using minimally invasive approach.^1–4 With focus on robotic surgery techniques, in this video we describe our standardized technical approach of robotic anatomical left hepatectomy with enbloc caudate lobe resection. Methods: A 78-year-old man presented with a caudate lobe cholangiocarcinoma infiltrating the caudate lobe and dorsal aspect of segment 4 with a very close proximity to the base of umbilical fissure. …

Clinical Practice Variation Among Pediatric Rheumatologists Treating Kawasaki Disease: Results Of A North American Survey, Daniel Ibanez, Bianca Lang, Julia Shalen, Ali Yalcindag, Linda Wagner-Weiner, Kenneth N Schikler, Shoghik Akoghlanian, Hulya Bukulmez, Kristen Hayward, Laura Berbert, Sivia Lapidus, Andrea A Ramirez, Cagri Yildirim-Toruner

Faculty, Staff and Students Publications

Background: The best treatment for children with KD who fail to respond to the first dose of IVIG (refractory KD) is currently unknown. The purpose of this study was to determine treatment practices of pediatric rheumatologists in North America who manage IVIG-refractory KD.

Methods: A 34-item web-based survey was sent to 102 randomly selected members of the Childhood Arthritis and Rheumatology Research Alliance (CARRA). The anonymous survey addressed the use of primary intensification as well as the treatment of IVIG-refractory KD.

Results: The response rate was 82%; 56% (all pediatric rheumatologists) completed the survey. Primary intensification was …

Target Consumers For Beef Jerky, Kynda R. Curtis, Makaylie Langford, Karin E. Allen, Ruby Ward

All Current Publications

This fact sheet describes the target market (consumer group) for packaged beef jerky, based on survey data collected from a Utah State University study in the fall of 2024. It includes details of the study and recommendations for beef jerky producers and retailers.

Rich County, Utah, Range Plants: A Condensed Field Guide, Elana Feldman, Katie Siesel, Reganne K. Briggs, Jan Reinhart, Staci Williams-Jones

All Current Publications

This guide is meant for land managers, producers, and natural resource professionals in Rich County, Utah, who are new to plant identification. This guide helps in quickly identifying common range plants in Rich County, Utah, and provides useful information about each species to aid management decisions.

Mbnl Loss Of Function In Smooth Muscle As A Model For Myotonic Dystrophy Associated Gastrointestinal Dysmotility, Janel A M Peterson, Jesus A Frias, Andrew N Miller, Krishnakant G Soni, Yi Zhang, Zheng Xia, John W Day, Geoffrey A Preidis, Thomas A Cooper

Faculty, Staff and Students Publications

Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy and severely affects multiple organ systems, including the brain, heart, skeletal muscle, and gastrointestinal (GI) tract. Despite 80% of individuals with DM1 experiencing GI dysfunction that affects their daily life, the mechanisms of GI dysmotility in DM1 remain an understudied aspect of the disease. DM1 is caused by a CTG repeat expansion in the DMPK gene that, when expressed as an expanded CUG repeat RNA, sequesters and reduces the activity of the muscleblind-like (MBNL) RNA-binding protein family. We developed a mouse line with conditional, smooth muscle-specific knockout of …

Unresectable Angiosarcoma Of The Head And Neck: A Case Report Highlighting Genomic Alterations, Targeted Therapy, And Clinical Response, Vasisht Karri, Samir Dalia

Student Publications

Angiosarcoma of the head and neck is an aggressive malignancy with limited therapeutic options when unresectable. We report the case of a 73-year-old male with advanced scalp and neck angiosarcoma characterized by MYC amplification and high tumor mutational burden. He received a multimodal treatment strategy including dual immune checkpoint blockade (nivolumab and ipilimumab) combined with cabozantinib, followed by paclitaxel and subsequent pazopanib. This approach achieved prolonged disease control exceeding 18 months, with manageable toxicities through dose adjustments and supportive care. Genomic profiling guided therapeutic decisions and highlighted the role of MYC amplification and tumor mutational burden as potential biomarkers for …

Neuropathic Pain And Related Depression In Mice: The Effect Of A Terpene And A Minor Cannabinoid In Combination, Jose Rios, Mohammed Alnoud, Mohammad Hussain, Zayd Ayas, Emmanuel Franco, Justin D. Mills, Joshua Nwose, Maria Sophia Malbas, Hiram L. Garcia, Manish Kumar Tripathi, Khalid Benamar

School of Medicine Publications

Background/Objectives: Neuropathic pain is one of the most severe types of chronic pain. Although it is difficult to manage, it often co-occurs with depression. Yet, no medication addresses the neuropathic pain and depression comorbidity. Therefore, developing integrated treatment strategies that address both pain and depression is a major public health priority and an unmet need affecting millions. Methods: In this study, we investigated the effect of combining a terpene, Beta-Caryophyllene (BCP), and cannabidiol (CBD) on neuropathic pain and associated depression. We employed a chronic constriction injury (CCI) neuropathic pain model and a series of behavioral tests to evaluate …

Molecular Effects Of Glucose On Mir503hg-Regulated Genes In Triple-Negative Breast Cancer, Victoria Reid, Barbara Yang, Kyle Russo, Melina J. Sedano, Ramesh Choudhari, Enrique I. Ramos, Shrikanth S. Gadad

School of Medicine Publications

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, characterized by a lack of key hormone receptors in tumor cells. As there are limited treatment options for these patients, it is crucial to understand the underlying mechanisms by which TNBC constantly evolves and evades treatments. In this regard, the pervasive nature of transcription provides a potential reservoir of transcripts, including both coding and noncoding, that TNBC leverages to sustain a proliferative advantage and support tumor growth. TNBC is affected by energy sources such as glucose, which can have a profound impact on gene expression regulation mediated by various …

Holter Monitor Qt Dispersion And Qtc-Dispersion In Pediatric Long Qt Syndrome And Development Of A Diagnostic And Arrhythmia Risk Prediction Model, Hadeel Allam, Na Le Dang, Edita Karasalihovic, Nathan Miller, Lisa Roelle, William B Orr, Dustin Nash, Anthony G Pompa, Jennifer N A Silva

2020-Current year OA Pubs

BACKGROUND: Holter monitors can provide temporal QT analysis, allowing for calculation of QT dispersion and corrected QT dispersion over time. We describe the results of the QT dispersion and corrected QT dispersion over a 24-hour period in pediatric patients with long QT syndrome (LQTS), compared with a normal cohort, and develop 2 new machine learning models for diagnosis and arrhythmia risk prediction in LQTS.

METHODS: A single-center retrospective case-control study was conducted comparing patients with congenital LQTS and normal controls who underwent a clinically indicated Holter between January 2022 and May 2024. After identifying patients with cardiac events, 2 neural …

Baseline Ecg And Cardiovascular Outcomes In People With Hiv: Insights From Reprieve, Aya Awwad, Shashwatee Bagchi, Et Al.

2020-Current year OA Pubs

BACKGROUND: With antiretroviral therapy, people with HIV (PWH) have an increased burden of cardiovascular disease. The REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) trial demonstrated that pitavastatin reduces major adverse cardiovascular events (MACEs) among PWH at low to moderate traditional atherosclerotic risk. Electrocardiographic abnormalities are common in PWH, but little is known about their association with MACEs. We sought to examine whether baseline electrocardiographic abnormalities are associated with increased MACE risk among a global primary cardiovascular disease prevention cohort of PWH in REPRIEVE.

METHODS: In this observational analysis, entry electrocardiographic abnormalities were adjudicated and classified as major or …

The Inferred Functional Connectome Underlying Circadian Synchronization In The Mouse Suprachiasmatic Nucleus, K L Nikhil, Bharat Singhal, Daniel Granados-Fuentes, Jr-Shin Li, István Z Kiss, Erik D Herzog

2020-Current year OA Pubs

Circadian rhythms in mammals arise from the spatiotemporal synchronization of ~20,000 neuronal clocks in the suprachiasmatic nucleus (SCN). Although anatomical, molecular, and genetic approaches have revealed diverse SCN cell types, how network-level wiring enables their synchronization remains unclear. To overcome the challenges of inferring functional connectivity from fixed tissue, we developed Mutual Information & Transfer Entropy (MITE), an information-theoretic framework to infer directed cell-cell connections with high fidelity from long-term live-cell imaging. Recording and analyzing 3,290 h of clock gene expression from 8,261 SCN neurons across 17 mice, we uncovered a highly conserved, sparse SCN network organized into two asymmetrically …

Exploiting Large Language Models For Diagnosing Autism Associated Language Disorders And Identifying Distinct Features, Chuanbo Hu, Wenqi Li, Mindi Ruan, Xiangxu Yu, Shalaka Deshpande, Lynn K Paul, Shuo Wang, Xin Li

2020-Current year OA Pubs

Diagnosing language disorders associated with autism is a complex challenge, often hampered by the subjective nature and variability of traditional assessment methods. In this study, we explored large language models (LLMs) to overcome the speed and precision obstacles by enhancing sensitivity and profiling linguistic features for autism diagnosis. This research utilizes natural language understanding capabilities of LLMs to simplify and improve the diagnostic process, focusing on identifying autism-related language patterns. We showed that the proposed method demonstrated improvements over the baseline models, with over a 10% increase in both sensitivity and positive predictive value in a zero-shot learning configuration. Combining …

Resident-Led Peer Support Groups In Emergency Medicine: A Pilot Framework For Peer Leader Training, Kyra D Reed, Alexandria P Weston, Alexandra E Serpe, Destiny D Folk, Jacob M Destrampe, Heather P Kelker, Aloysius J Humbert, Katie E Pettit, Julie L Welch

2020-Current year OA Pubs

Peer support has demonstrated efficacy in alleviating symptoms of anxiety and depression, while fostering empathy and mitigating burnout among healthcare professionals. Given the considerable demands of residency training, there is a strong rationale for resident-led peer support interventions. However, structured programs to train residents for such leadership roles remain limited. Our objective was to implement a peer support leader training program for residents, evaluate its perceived effectiveness, and identify common themes discussed in sessions. Between June 2021 and June 2023, we performed a longitudinal, prospective cohort survey study of Emergency Medicine (EM) and EM/Pediatrics (EM/P) residents participating in a novel …

Wdfy4-Dependent Cross-Presentation Proceeds Via A Vacuolar Antigen-Processing Route, J Luke Postoak, Alyssa Koch, Sicong Shan, Ray A Ohara, Suin Jo, Jing Chen, Pritesh Desai, Feiya Ou, Magdalena Kraft, Michael S Diamond, Sunkyung Kim, Theresa L Murphy, Kenneth M Murphy

2020-Current year OA Pubs

The intracellular processing route used by type I conventional dendritic cells (cDC1) for cross-presentation of viral- or tumor-associated antigens remains controversial. One model proposes that captured antigens exit from damaged phagolysosomes and enter the cytosol, where they are processed for presentation by MHC class I molecules (MHC-I). This model relies on proteasomal degradation and TAP-dependent peptide transport into the endoplasmic reticulum (ER) for loading by the peptide loading complex (PLC). An alternative model proposes a vesicular route in which captured antigens are retained and processed within an endocytic compartment. A compelling argument favoring the cytosolic model is the dramatic loss …

Intracellular Acinetobacter Baumannii Acts As A Transient Reservoir In Lung Infection Via A "Persist And Resist" Strategy, Manon Janet-Maitre, Gisela Di Venanzio, Clay D Jackson-Litteken, Nichollas E Scott, Mario F Feldman

2020-Current year OA Pubs

Although considered primarily extracellular,

A Proteogenomic Gene Signature Defines Prognostic Subgroups Highlighting Pi3k/Akt/Mtor Signaling Pathway As A Therapeutic Vulnerability In Myeloid Malignancies, Fan He, Shuyang Lin, Bei Gao, Varun Ramesh, Alexander B Kim, Tim Kong, Daniel A C Fisher, Christopher T Letson, Molly Brakhane, Mary Fulbright, Yanbo Yu, Marco Sardiello, Jorge Di Paola, Stephen M Sykes, Stephen T Oh

2020-Current year OA Pubs

INTRODUCTION: Myeloid malignancies, including acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPN), exhibit overlapping pathophysiology. Chronic MPNs can transform into secondary AML (sAML), which is associated with poor prognosis and limited treatment options. However, the process and prognostic significance of leukemic transformation remain incompletely understood.

METHOD: Through a two-sample bidirectional Mendelian randomization (MR) analysis, we showed that genetic liability to MPN significantly predicts the risk of developing AML, establishing MPN as the precursor to leukemia. To identify mediators of this risk, we integrated population-level plasma proteomics data, identifying 55 proteins associated with MPN. Upon integrative analysis with the BEAT-AML cohort, …

Dynamic Generation Of Contextual User Interface Controls From Content Analysis, Sönke Rohde, Alan Ross, Carsten Hinz

Defensive Publications Series

User interfaces for content generation and manipulation can be limited by static controls or ambiguous inputs that may not provide precise, context-specific tools. The disclosed technology relates to a system that can programmatically generate adaptive user interface (UI) controls based on content analysis. This system can analyze a corpus, such as an image or document, to perform semantic inference and derive manipulable properties. These properties can be mapped to declarative UI definitions for controls, such as sliders or dropdown menus, which can be rendered by a host application. This process can provide a user with context-aware controls tailored to specific …

The Ψ-Theory: Unifying Cosmology And Quantum Mechanics Through A Dynamic Temporal Metric, Valerii Y. Vorobiev

Defensive Publications Series

We propose the Ψ-Theory, a novel ontological framework that addresses fundamental crises in modern cosmology by redefining the nature of time and gravity. The theory posits a primary scalar (or, fundamentally, tensorial) field Ψ, which is not a traditional force field, but a metric of the local density of causal interactions (quantum "Acts") in the network of reality. From this field, the observable geometry of spacetime and the phenomenon of gravity emerge as secondary, effective descriptions. The core principle is that time is not a background entity, but a dynamic, relational metric of causal connectivity. The Ψ-field dictates the local …