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Articles 155221 - 155250 of 156505
Full-Text Articles in Entire DC Network
Coating Of Zinc Substrates With Fluorosilane Molecules Using A Water-Treatment Technique As A Pre-Coating Procedure For The Creation Of Superhydrophobic Surfaces, Renz Ronald R. Prieto, Marvin U. Herrera
Coating Of Zinc Substrates With Fluorosilane Molecules Using A Water-Treatment Technique As A Pre-Coating Procedure For The Creation Of Superhydrophobic Surfaces, Renz Ronald R. Prieto, Marvin U. Herrera
Journal of Metals, Materials and Minerals
Superhydrophobic surfaces were successfully created when zinc substrates were coated with molecules with low surface energy through grafting of fluorosilane molecules. The zinc substrate underwent water-treatment technique as a pre-coating procedure to enhance the reaction sites for the grafting of fluorosilane molecules. The water contact angle of the samples went as high as 161.1° ± 0.8°. At lower fluorosilane-ethanol soaking times, water contact angles have lower values while at higher soaking time, it has higher water contact angle values. At 240 min fluorosilane-ethanol soaking time, optimum value of water contact angle was achieved. Fluorosilane molecules are widely distributed through the …
Sulfur-Doped Carbon Dots Derived From Caffeine: A Highly Efficient Photocatalyst For Organic Dye Degradation, Ganyaporn Wongwaen, Koranut Dechsri, Praneet Opanasopit, Montri Aiempanakit, Cheewita Suwanchawalit
Sulfur-Doped Carbon Dots Derived From Caffeine: A Highly Efficient Photocatalyst For Organic Dye Degradation, Ganyaporn Wongwaen, Koranut Dechsri, Praneet Opanasopit, Montri Aiempanakit, Cheewita Suwanchawalit
Journal of Metals, Materials and Minerals
Sulfur-doped carbon dots (S-doped CDs) were synthesized via a solvothermal method using caffeine as a carbon precursor and sodium sulfide as a sulfur source. Characterization using transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR), ultraviolet -visible (UV-Vis) spectroscopy, and photoluminescence spectroscopy (PL) confirmed successful sulfur incorporation. TEM revealed a uniform size distribution and graphitic structures, while UV-Vis analysis showed a reduction in the bandgap from 3.29 eV to 3.10 eV, improving light absorption and charge carrier separation. The photocatalytic activity of S-doped CDs was evaluated for indigo carmine (IC) dye degradation under UV irradiation, where 2S-CDs …
Fem Modeling And Comparative Study Of Graphite Lubricants In The Hot Forging Of Aisi 1045 Medium Carbon Steel, Raschanan Poungprasert, Nattarawee Siripath, Naiyanut Jantepa, Surasak Suranuntchai
Fem Modeling And Comparative Study Of Graphite Lubricants In The Hot Forging Of Aisi 1045 Medium Carbon Steel, Raschanan Poungprasert, Nattarawee Siripath, Naiyanut Jantepa, Surasak Suranuntchai
Journal of Metals, Materials and Minerals
This study investigates the performance of water-based and oil-based graphite lubricants in the hot forging of AISI 1045 medium carbon steel, aiming to enhance product quality while minimizing die wear. Utilizing Finite Element Method (FEM) simulations and experimental analysis, we examined key factors including flow lines, dimensional accuracy, forging load, and die wear. Results indicate that oil-based graphite lubricants significantly outperform water-based options, achieving a lower average error of 0.26% in dimensional accuracy compared to 0.99% for water-based lubricants. Additionally, oil-based lubricants resulted in reduced forming loads, leading to improved energy efficiency and longer die life. Microstructural analysis revealed that …
Impacts Of Calcination Temperature On The Crystallography, Granulometry And Impedance Of Licomno4, Chee Wayne Tan, Zul Hilmi Che Daud, Zainab Asus, Mohd Hasbullah Idris, Izhari Izmi Mazali, Mohd Kameil Abdul Hamid
Impacts Of Calcination Temperature On The Crystallography, Granulometry And Impedance Of Licomno4, Chee Wayne Tan, Zul Hilmi Che Daud, Zainab Asus, Mohd Hasbullah Idris, Izhari Izmi Mazali, Mohd Kameil Abdul Hamid
Journal of Metals, Materials and Minerals
Spinel structured lithium cobalt manganese oxide (LiCoMnO4) which exhibit reduction potential surpassing 5.0 V (vs. Li0 | Li+) was identified to be one of the prospective cathode candidates for next generation lithium-ion electrochemical systems. This article highlights the significance of calcination temperature on the crystallography of the resultant electroceramic compound as well as the corresponding response on the granulometry and impedance of LiCoMnO4. LiCoMnO4 compounds synthesised via sol-gel reaction in the first instance were converted into xerogel and subsequently subjected to facile one-step calcination protocol. Crystallography of the post-calcinated compounds were characterised via powder x-ray diffraction (XRD) technique. Temperature ranging …
Effect Of Compaction Pressure On The Structure And Mechanical Properties Of Functionally Graded Aluminium-Glass Microsphere (Fgagm) Foams Produced By Powder Metallurgy Process, Vicheka Moeun, Seksak Asavavisithchai
Effect Of Compaction Pressure On The Structure And Mechanical Properties Of Functionally Graded Aluminium-Glass Microsphere (Fgagm) Foams Produced By Powder Metallurgy Process, Vicheka Moeun, Seksak Asavavisithchai
Journal of Metals, Materials and Minerals
Functionally graded aluminium-glass microsphere (FGAGM) foams were successfully fabricated via powder metallurgy. The influence of compaction pressure on the structural and mechanical properties of the foams was systematically investigated. The study observed that increasing compaction pressure enhanced the green (pre-sintering) density of FGAGM foam, while post-sintering densities exhibited a decreasing trend with higher compaction pressures. The mechanical examination indicated that mechanical properties improved significantly with higher compaction pressures. While higher compaction pressures generally improve mechanical properties, the study identified that excessive pressures could lead to the fracture of GM particles, introducing defects that compromise the foam's structural integrity. Therefore, determining …
Effect Of Lanthanum Doping On Phase Transition, Piezoelectric And Energy Storage Properties Of Lead-Free 0.93(Bi0.5na0.5)Tio3‒0.07batio3 Ceramics, Pathit Premwichit, Songphop Jaila, Sasiporn Prasertpalichat
Effect Of Lanthanum Doping On Phase Transition, Piezoelectric And Energy Storage Properties Of Lead-Free 0.93(Bi0.5na0.5)Tio3‒0.07batio3 Ceramics, Pathit Premwichit, Songphop Jaila, Sasiporn Prasertpalichat
Journal of Metals, Materials and Minerals
In this study, lead-free (Bi0.465Na0.465Ba0.07)(1–x)LaxTiO3 (x=0.0‒0.04) ceramics were synthesized using a conventional solid-state reaction method. All samples showed a single-phase perovskite structure with pseudocubic symmetry. The dense microstructure revealed a decrease in average grain size as x increased. La3+ addition stabilized polar nanoregions (PNRs), shifting the ferroelectric to relaxor phase transition temperature (TF₋R=104℃ for x=0.0) to below room temperatures as La3+ content increased. This resulted in a transition from a rectangular to a relaxor-like thin P–E loop (x≥0.01), indicating a shift from ferro-electric (FE) to relaxor ferroelectric (RFE), which …
Structural Tuning Of Bioi Toward Bi O /Agi Heterostructures Via Room-Temperature Ion Exchange For Improved Photocatalytic Activity, Varunya Atimayulerd, Sorawit Thueanbangyang, Kittiyaporn Singsumphan, Ganyaporn Wongwaen, Cheewita Suwanchawalit, Montri Aiempanakit
Structural Tuning Of Bioi Toward Bi O /Agi Heterostructures Via Room-Temperature Ion Exchange For Improved Photocatalytic Activity, Varunya Atimayulerd, Sorawit Thueanbangyang, Kittiyaporn Singsumphan, Ganyaporn Wongwaen, Cheewita Suwanchawalit, Montri Aiempanakit
Journal of Metals, Materials and Minerals
In this work, a bismuth oxide/silver iodide (Bi2O3/AgI) heterojunction photocatalyst was successfully fabricated via a room-temperature ion exchange process using bismuth oxyiodide (BiOI) as a morphology-directing precursor. Building upon our previous work on solvent-modulated BiOI nanostructures, this study employs a chemical transformation route to develop interfacially connected heterostructures while preserving key morphological features. Structural, morphological, and optical characterizations, including X-ray diffraction, field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, Fourier-transform infrared spectroscopy, and ultraviolet–visible diffuse reflectance spectroscopy, provided supporting evidence for the successful formation of Bi2O3/AgI heterojunctions with likely close interfacial contact. The optimized Bi2O3/AgI composite with a 50:50 mass ratio …
Aluminium Oxide Particles-Containing Organogels For Cleaning Of Optical Glass Surfaces, Galina Vladimirovna Lyamina, Oksana Valerievna Dubinina, Alfa Edison I Lela
Aluminium Oxide Particles-Containing Organogels For Cleaning Of Optical Glass Surfaces, Galina Vladimirovna Lyamina, Oksana Valerievna Dubinina, Alfa Edison I Lela
Journal of Metals, Materials and Minerals
Hypothesis: Some types of cleaning methods are not very effective and can actually increase damage to the optical parts being cleaned. As an alternative to these methods, we propose the use of gel-like substances to remove contaminants from optical surfaces. We have developed a method for cleaning optical glass surfaces that uses organogels, which are based on copolymers of methyl methacrylate and methacrylic acid. These organogels are loaded with polyethylene glycol, and aluminum oxide particles (Al2O3), which help to effectively remove contaminants without causing damage to the surface. Experiments: Al2O3 nanoparticles prepared by a Nano Spray Dryer were added to …
Improving Outcomes Of Single-Sided Deaf Cochlear Implant Users By Reducing Interaural Frequency And Loudness Mismatches Through Device Programming, Laura K Holden, Rosalie M Uchanski, Noël Y Dwyer, Ruth M Reeder, Timothy A Holden, Jill B Firszt
Improving Outcomes Of Single-Sided Deaf Cochlear Implant Users By Reducing Interaural Frequency And Loudness Mismatches Through Device Programming, Laura K Holden, Rosalie M Uchanski, Noël Y Dwyer, Ruth M Reeder, Timothy A Holden, Jill B Firszt
2020-Current year OA Pubs
The study aimed to improve outcomes in Nucleus cochlear implant (CI) recipients with single-sided deafness (SSD) by reducing interaural frequency and loudness mismatches through device programming. In Experiment 1a, a modified frequency allocation table (FAT) was created to better match the tonotopicity of the contralateral ear and reduce interaural frequency mismatch. Twenty experienced SSD-CI users completed localization and speech recognition tests with their everyday FAT. Tests were repeated after 6 weeks' use of the modified FAT. Participants compared both FATs for 2 weeks before being tested again with each. For 10 newly implanted SSD-CI recipients (Experiment 1b), Group A was …
Colorectal Cancer Incidence Trends In Younger Versus Older Adults: An Analysis Of Population-Based Cancer Registry Data, Hyuna Sung, Rebecca L Siegel, Mathieu Laversanne, Chenxi Jiang, Eileen Morgan, Mariam Zahwe, Yin Cao, Freddie Bray, Ahmedin Jemal
Colorectal Cancer Incidence Trends In Younger Versus Older Adults: An Analysis Of Population-Based Cancer Registry Data, Hyuna Sung, Rebecca L Siegel, Mathieu Laversanne, Chenxi Jiang, Eileen Morgan, Mariam Zahwe, Yin Cao, Freddie Bray, Ahmedin Jemal
2020-Current year OA Pubs
BACKGROUND: Previous studies have shown that colorectal cancer incidence is increasing among younger adults (aged < 50 years) in multiple high-income western countries in contrast with stabilising or decreasing trends in incidence in older adults (aged ≥50 years). This study aimed to investigate contemporary colorectal cancer incidence trends in younger adults versus older adults.
METHODS: Colorectal cancer incidence data, including year of diagnosis, sex, and 5-year age group for 50 countries and territories, were extracted from the WHO-International Agency for Research on Cancer Cancer Incidence in Five Continents Plus database. The Human Development Index 2022 was retrieved from the United Nations Development Programme and grouped into very high (>0·80), high (0·70-0·79), medium (0·55-0·69), and low (< 0·55) categories. Age-standardised incidence rates (ASR) per 100 000 person-years of early-onset (diagnosed between ages 25 to 49 years) and late-onset (diagnosed between ages 50 to 74 years) colorectal cancer (ICD 10th revision, C18-20), diagnosed between 1943-2003 and 2015-17, were calculated using the direct method and Segi-Doll world standard population). The primary study objective was to examine contemporary colorectal cancer incidence trends in younger adults versus older adults using data until 2017 from 50 countries and territories. Temporal trends were visualised and quantified with joinpoint regression, stratified by age at diagnosis (25-49 years or 50-74 years). Average annual percentage changes (AAPC) were estimated.
FINDINGS: In the most recent 5 years (2013-17 for all countries analysed, except for Japan [2011-15], Spain [2012-16], and Costa Rica [2012-16]), …
Surgeon Interpretation Of Patient-Reported Outcome Measures In Upper Extremity Osteoarthritis, Rick S. Looman, Koen Oude Nijhuis, Sina Ramtin, David Ring, Daniel A. London, Ryan Calfee, Niels Brinkman, Science Of Variation Group
Surgeon Interpretation Of Patient-Reported Outcome Measures In Upper Extremity Osteoarthritis, Rick S. Looman, Koen Oude Nijhuis, Sina Ramtin, David Ring, Daniel A. London, Ryan Calfee, Niels Brinkman, Science Of Variation Group
2020-Current year OA Pubs
PURPOSE: Measures that quantify levels of pain intensity, incapability, symptoms of distress, and unhelpful thinking were designed as research tools. We studied how surgeons interpret and act on these scores in the care of individual patients.
METHODS: In an online experiment, 67 upper limb specialists from the Science of Variation Group reviewed 10 fictious patient scenarios of trapeziometacarpal, wrist and elbow osteoarthritis (OA) and randomized elements of radiographic severity, levels of discomfort and incapability, deprivation index score (social health), and levels of distress and unhelpful thinking (mental health). Multilevel mixed-effects linear regression identified patient factors associated with surgeon concern, enthusiasm …
Ethical Implications Of Neurotechnology In Industry-Academia Partnerships: Insights From Patient And Research Participant Interviews, Meredith V. Parsons, Maya Skolnik, Judith Mwobobia, Erin D Solomon, James M. Dubois, Tristan Mcintosh
Ethical Implications Of Neurotechnology In Industry-Academia Partnerships: Insights From Patient And Research Participant Interviews, Meredith V. Parsons, Maya Skolnik, Judith Mwobobia, Erin D Solomon, James M. Dubois, Tristan Mcintosh
2020-Current year OA Pubs
BACKGROUND: Neurotechnologies often advance through industry-academia (IA) partnerships and offer insight into brain and nervous system functions, bringing improved diagnosis and treatment options to patients. Both neurotechnology and IA partnerships pose ethical challenges that can impact research participation experiences, patient treatment, and health outcomes.
METHODS: Investigators conducted interviews with 16 patients who used neurotechnology devices in therapeutic or research settings. Interviews explored participants' experiences using neurotechnology, perspectives on IA partnerships, preferences for neural data use and long-term care, and advice for future neurotechnology device users. Data were analyzed using inductive thematic analysis.
RESULTS: Participants were generally supportive of IA partnerships. …
Articles That May Change Your Practice: Reviewing Intraosseous Or Intravenous? Reviewing Intraosseous Versus Intravenous First Approach To Access In Out-Of-Hospital Cardiac Arrest Data From Randomized Controlled Trials, Blaise Loughman, Fatou Ndaw, Aaron J Lacy, James L Li
Articles That May Change Your Practice: Reviewing Intraosseous Or Intravenous? Reviewing Intraosseous Versus Intravenous First Approach To Access In Out-Of-Hospital Cardiac Arrest Data From Randomized Controlled Trials, Blaise Loughman, Fatou Ndaw, Aaron J Lacy, James L Li
2020-Current year OA Pubs
No abstract provided.
Articles That May Change Your Practice: Double-Sequential External Defibrillation In Out-Of-Hospital Cardiac Arrest, Michael J Defilippo, Christianne L Jafari, James L Li, Aaron J Lacy
Articles That May Change Your Practice: Double-Sequential External Defibrillation In Out-Of-Hospital Cardiac Arrest, Michael J Defilippo, Christianne L Jafari, James L Li, Aaron J Lacy
2020-Current year OA Pubs
No abstract provided.
Usability Of The Mayo Test Drive Remote Self-Administered Web-Based Cognitive Screening Battery In Adults Aged 35-100 With And Without Cognitive Impairment, Jay S Patel, Jason Hassenstab, Et Al.
Usability Of The Mayo Test Drive Remote Self-Administered Web-Based Cognitive Screening Battery In Adults Aged 35-100 With And Without Cognitive Impairment, Jay S Patel, Jason Hassenstab, Et Al.
2020-Current year OA Pubs
BACKGROUND: Mayo Test Drive (MTD): Mayo Test Development through Rapid Iteration, Validation and Expansion, is a web-based remote cognitive assessment platform for self-administered neuropsychological measures with previously demonstrated validity and reliability. We examined the usability of MTD and hypothesized that completion rates would be greater than 90%. We explored whether completion and participation rates differed by cognitive status and demographic factors.
METHODS: A total of 1,950 Mayo Clinic Study of Aging and Mayo Alzheimer's Disease Research Center participants (97% White, 99% Non-Hispanic) were invited to participate in this ancillary, uncompensated remote study. Most invitees were cognitively unimpaired (CU;
RESULTS: Baseline …
System Readiness And The Patient Care Pathway For Alzheimer's Disease Diagnosis And Treatment, B Joy Snider, Et Al.
System Readiness And The Patient Care Pathway For Alzheimer's Disease Diagnosis And Treatment, B Joy Snider, Et Al.
2020-Current year OA Pubs
Promising therapeutic interventions that target the underlying pathophysiology are changing the landscape of Alzheimer's disease (AD) research. The AD care pathway must be transformed to meet the challenge of bringing these new therapies to the increasing number of people living with AD within the existing healthcare framework. Challenges include identifying patients who may benefit from treatment interventions early in the course of the disease, ensuring that diagnostic tools are accessible and accurate, and developing capabilities to monitor the effectiveness of interventions over time. These challenges must be addressed at all levels, from primary care settings to tertiary treatment centers; this …
Clinical And Neuropathological Associations Of Plasma Aβ42/Aβ40, P-Tau217 And Neurofilament Light In Sporadic Frontotemporal Dementia Spectrum Disorders, Binita Rajbanshi, Randall J Bateman, Et Al.
Clinical And Neuropathological Associations Of Plasma Aβ42/Aβ40, P-Tau217 And Neurofilament Light In Sporadic Frontotemporal Dementia Spectrum Disorders, Binita Rajbanshi, Randall J Bateman, Et Al.
2020-Current year OA Pubs
INTRODUCTION: Plasma amyloid beta
METHODS: We compared the clinical, neuroimaging, and neuropathological associations of plasma Aβ
RESULTS: Aβ
DISCUSSION: Plasma p-tau217 has clinical, neuroimaging, and neuropathological correlates in sporadic FTD and may identify FTD cases with AD co-pathology.
HIGHLIGHTS: Alzheimer's disease (AD) features could be identified with plasma phosphorylated tau217 (p-tau217) in frontotemporal lobar degeneration (FTLD).Plasma p-tau217 is a better discriminator of AD co-pathology and AD-associated features in FTLD than plasma amyloid beta
Estimating Preclinical Amyloid Positivity: A Case Study Transporting Adni To Aric, Emma K Stapp, Elizabeth Rose Mayeda, Elizabeth A Stuart, Rebecca F Gottesman, Scott C Zimmerman, Dean F Wong, Thomas H Mosley, Michael E Griswold, M Maria Glymour, Melinda C Power, Alzheimer's Disease Neuroimaging Initiative
Estimating Preclinical Amyloid Positivity: A Case Study Transporting Adni To Aric, Emma K Stapp, Elizabeth Rose Mayeda, Elizabeth A Stuart, Rebecca F Gottesman, Scott C Zimmerman, Dean F Wong, Thomas H Mosley, Michael E Griswold, M Maria Glymour, Melinda C Power, Alzheimer's Disease Neuroimaging Initiative
2020-Current year OA Pubs
INTRODUCTION: Alzheimer's disease and related dementias researchers have benefited from deeply phenotyped clinical samples; however, there is a critical need for estimates that generalize to diverse, representative populations. Use of a statistical approach from causal inference, "transport," may allow generalization of findings from clinical samples to other target populations. Here we explore the feasibility and validity of extending results from a clinical sample, the Alzheimer's Disease Neuroimaging Initiative (ADNI), to a community-based target sample, the Atherosclerosis Risk in Communities Study Positron Emission Tomography Amyloid Imaging Study (ARIC-PET) using transport estimation and a standard approach, direct standardization, which itself can be …
Enhancing Safety: Multi-Institutional Fmea And Fta On 177 Lu-Based Radio-Pharmaceutical Therapy, Siju C George, Santiago Aguirre, Nichole M Maughan, Ranjini Tolakanahalli, E James Jebaseelan Samuel, Sven L Gallo, Jacqueline E Zoberi, Yongsook C Lee
Enhancing Safety: Multi-Institutional Fmea And Fta On 177 Lu-Based Radio-Pharmaceutical Therapy, Siju C George, Santiago Aguirre, Nichole M Maughan, Ranjini Tolakanahalli, E James Jebaseelan Samuel, Sven L Gallo, Jacqueline E Zoberi, Yongsook C Lee
2020-Current year OA Pubs
PURPOSE: This study investigates potential failure modes and conducts failure mode and effects analysis (FMEA) and fault tree analysis (FTA) on the administration of
METHODS: We reviewed the literature to investigate the administration of Pluvicto and Lutathera, focusing on prospective procedural failures and potential failure modes (PFMs) and their outcomes. We distributed an FMEA survey to multiple experienced centers in
RESULTS: The findings from the literature review and survey responses on the prospective study have identified several critical areas at risk of failure. These areas include non-optimized treatment delivery, inadequate patient monitoring, and lack of safety training, leading to radiation …
Impact Of Genetic Counseling And Testing In Individuals At High Risk Of Familial Alzheimer's Disease From Latin America: A Non-Randomized Controlled Trial, Pablo M Bagnati, Ellen Ziegemeier, Eric Mcdade, Randall J Bateman, Jorge J Llibre-Guerra, Et Al.
Impact Of Genetic Counseling And Testing In Individuals At High Risk Of Familial Alzheimer's Disease From Latin America: A Non-Randomized Controlled Trial, Pablo M Bagnati, Ellen Ziegemeier, Eric Mcdade, Randall J Bateman, Jorge J Llibre-Guerra, Et Al.
2020-Current year OA Pubs
INTRODUCTION: This study involved evaluating a tailored genetic counseling and testing (GCT) protocol for families at risk of autosomal dominant Alzheimer's disease (ADAD) in Latin America (LatAm), focusing on essential cultural and regional adaptations.
METHODS: We conducted a non-randomized controlled trial among ADAD families in Colombia and Argentina. Participants were categorized based on their decision to learn their genetic status (GS), with further comparisons between mutation-positive versus mutation-negative participants who learned their status. Psychological impacts were measured using validated scales for anxiety and depression.
RESULTS: Of the 122 eligible participants, 97 completed the GCT protocol, and 87 opted to learn …
Chronic Recurrent Multifocal Osteomyelitis-Like Paraneoplastic Syndrome As Initial Presentation Of Nodular Sclerosis Classical Hodgkin Lymphoma, Michel Attieh, Seyed Reza Taha, Selim Nasser, Fouad Boulos
Chronic Recurrent Multifocal Osteomyelitis-Like Paraneoplastic Syndrome As Initial Presentation Of Nodular Sclerosis Classical Hodgkin Lymphoma, Michel Attieh, Seyed Reza Taha, Selim Nasser, Fouad Boulos
2020-Current year OA Pubs
Hodgkin lymphoma (HL) presenting with initial skeletal symptoms as a paraneoplastic phenomenon is extremely rare. Herein, we report the case of a 26-year-old man with nodular sclerosis classical HL (NSCHL) who presented with low back pain as the initial symptom. Imaging studies were unremarkable except for right S1-S2 sacral marrow edema on MRI, and multiple biopsies showed only inflammatory changes, resulting in a tentative diagnosis of chronic recurrent multifocal osteomyelitis. Later in the course of the disease, after performing routine series of MRIs, lymphadenopathy was finally detected. Core biopsies of the axillary and pelvic lymph nodes subsequently confirmed the diagnosis …
Association Of Item-Level Responses To Cognitive Function Index With Tau Pathology And Hippocampal Volume In The A4 Study, Idris Demirsoy, Elham Ghanbarian, Babak Khorsand, Bhargav T Nallapu, Kellen K Petersen, Richard B Lipton, S Ahmad Sajjadi, Laura A Rabin, Ali Ezzati
Association Of Item-Level Responses To Cognitive Function Index With Tau Pathology And Hippocampal Volume In The A4 Study, Idris Demirsoy, Elham Ghanbarian, Babak Khorsand, Bhargav T Nallapu, Kellen K Petersen, Richard B Lipton, S Ahmad Sajjadi, Laura A Rabin, Ali Ezzati
2020-Current year OA Pubs
INTRODUCTION: Alzheimer's disease (AD) has a long preclinical phase in which individuals may accumulate amyloid beta (Aβ) and tau pathology without noticeable cognitive impairment. Subjective cognitive impairment reports can provide early insights into cognitive decline.
METHODS: In the A4 Study, 339 cognitively unimpaired, Aβ-positive individuals underwent tau positron emission tomography imaging. Tau status was classified based on medial temporal lobe tau standardized uptake value ratios (tau
RESULTS: Higher tau
DISCUSSION: These findings support the utility of participant- and study partner-reported concerns as early indicators of preclinical AD pathology, with potential value for early detection and trial enrichment strategies.
HIGHLIGHTS: Higher …
Stated Preference Research In Otolaryngology: A Scoping Review, Lucy Xu, Molly N Huston, Victoria S Lee, John D Cramer, Deborah Goss, Matthew R Naunheim
Stated Preference Research In Otolaryngology: A Scoping Review, Lucy Xu, Molly N Huston, Victoria S Lee, John D Cramer, Deborah Goss, Matthew R Naunheim
2020-Current year OA Pubs
OBJECTIVE: Stated preference research methods, including discrete choice experiments (DCEs), conjoint analysis (CA), best-worst scaling (BWS), and willingness-to-pay/contingent valuation (WTP/CV) studies, are excellent tools for understanding patient preferences in healthcare. Their application in otolaryngology has yet to be described. This work encompasses a scoping review assessing the field of stated preference research in otolaryngology, to identify gaps in the current literature and identify areas of future applications of such methodologies.
DATA SOURCES: Embase, Medline, and Web of Science.
REVIEW METHODS: A search of three databases for all relevant publications through 2023 was performed using relevant search terms. Eligibility criteria for …
Protocol For The Asian Cohort For Alzheimer's Disease (Acad) Study, Pei-Chuan Ho, Walter A Kukull, Et Al.
Protocol For The Asian Cohort For Alzheimer's Disease (Acad) Study, Pei-Chuan Ho, Walter A Kukull, Et Al.
2020-Current year OA Pubs
INTRODUCTION: To address knowledge gaps in Alzheimer's disease (AD) research, the Asian Cohort for Alzheimer's Disease (ACAD) Study will recruit over 5000 participants of Asian descent aged 60 or older in the United States and Canada. The current focus is on participants with Chinese, Korean, or Vietnamese ancestry, with the goal of characterizing both genetic and non-genetic risk factors. ACAD has assembled a culturally and linguistically appropriate data collection protocol, as well as a biosample collection protocol. Recruitment strategies follow community-based participatory research (CBPR) approaches to encourage research participation and engage Asian communities in brain health education.
METHODS: The ACAD …
Discovering Subtypes With Imaging Signatures In The Motoric Cognitive Risk Syndrome Consortium Using Weakly Supervised Clustering, Bhargav Teja Nallapu, Kellen K Petersen, Et Al.
Discovering Subtypes With Imaging Signatures In The Motoric Cognitive Risk Syndrome Consortium Using Weakly Supervised Clustering, Bhargav Teja Nallapu, Kellen K Petersen, Et Al.
2020-Current year OA Pubs
INTRODUCTION: Understanding the heterogeneity of brain structure in individuals with the Motoric Cognitive Risk Syndrome (MCR) may improve the current risk assessments of dementia.
METHODS: We used data from six cohorts from the
RESULTS: Three subgroups (Groups A, B, and C) were identified through MRI-based clustering with significant differences in regional brain volumes, gait speeds, and performance on Trail Making (Part-B) and Free and Cued Selective Reminding Tests.
DISCUSSION: Based on structural MRI, our results reflect heterogeneity in the population with moderate and slow gait, including those with MCR. Such a data-driven approach could help pave new pathways toward dementia …
Variations In Greater Trochanter Height As A Relation To Patient Demographics: Implications For Femoral Nail Design, Jordan A Haber, Amogh I Iyer, Matthew Dulas, Douglas Weaver, Jason A Strelzow
Variations In Greater Trochanter Height As A Relation To Patient Demographics: Implications For Femoral Nail Design, Jordan A Haber, Amogh I Iyer, Matthew Dulas, Douglas Weaver, Jason A Strelzow
2020-Current year OA Pubs
Intramedullary nail fixation is the "gold standard" for surgical intervention of femoral fractures. While many aspects of nail design and patient anatomy have received specific focus, anatomic variations in proximal femoral geometry and greater trochanteric height variation have been poorly studied. Understanding the potential relationship of the greater trochanter to patient demographics may provide an opportunity to improve implant placement. Retrospective review of x-ray and computed tomography images of the proximal femur was performed. Inclusion criteria consisted of skeletally mature patients over 18 years old with imaging of the proximal femur. Inclusion criteria identified 296 patients. Mean age of included …
Physical Activity As A Resistance Or Resilience Mechanism In Down Syndrome Alzheimer's Disease, Victoria L Fleming, Beau M Ances, Et Al.
Physical Activity As A Resistance Or Resilience Mechanism In Down Syndrome Alzheimer's Disease, Victoria L Fleming, Beau M Ances, Et Al.
2020-Current year OA Pubs
INTRODUCTION: Adults with Down syndrome (DS) are at risk for Alzheimer's disease (AD). Lifestyle factors such as engagement in moderate-to-vigorous physical activity (MVPA) reduce risk or delay the onset of AD. This study aimed to determine whether MVPA confers a
METHODS: Analyses included 69 adults with DS (aged 26-58) who participated in a longitudinal study across 3.29 years. An actigraphy accelerometer assessed MVPA across 7 days. Directly administered and informant-reported measures assessed cognitive functioning, specifically memory and dementia symptoms. Neuroimaging biomarkers quantified amyloid beta (Aβ) burden, as assessed via positron emission tomography imaging.
RESULTS: In regression models, baseline MVPA was …
Aku Libraries Annual Report - 2025, Office Of The University Librarian
Aku Libraries Annual Report - 2025, Office Of The University Librarian
Office of the University Librarian Reports
- Message by Peter Gatiti Associate Vice Provost & University Librarian
- The Beautiful Nakawa Campus Library
- AKU Author’s Day 2025
- Celebrating 5 Years of AKU Author’s Day: Bold Voices, Powerful Stories, Lasting Impact.
- A Student’s Journey into Co-Authoring Neuroscience
- My Fear of Academic Writing
- University Library Strategic Plan 2024-2029
- Lecture Series on Open Science
- Behind the Scenes
- Our Libraries & Students
- Book Conversations…
- RFID Technology at AKU Libraries
- Video Editing: Where Vision Meets Creativity
- Preserving Today for Tomorrow
- “Our Collections Matter”
- The FMIC Library
- …
Extreme Value Theory Analysis Of High Emitter Trends Across Four Us Cities From 1995 To 2021, M. Matti Maricq, Gary A. Bishop
Extreme Value Theory Analysis Of High Emitter Trends Across Four Us Cities From 1995 To 2021, M. Matti Maricq, Gary A. Bishop
Fuel Efficiency Automobile Test Publications
Extreme value theory provides a direct means to characterize the distribution of high emitters within a vehicle fleet and calculate statistical confidence intervals for comparisons. Defining a “high emitter” as the maximum emitter in a random sample of N vehicles implies in the limit of large N that high emitters follow an extreme value distribution, comprised of three distinct domains. The analysis of over twenty years of roadside remote sensing emissions measurements in Chicago, Denver, Los Angeles and Tulsa reveals clear differences between gasoline vehicle high emitter distributions across pollutants (hydrocarbons (HC), carbon monoxide (CO) and nitric oxide (NO)), but …
Barriers And Motivators To Attending Group Exercise Classes In Women With Anxiety, Depression And Post-Traumatic Stress Disorder, Sarah Ford
Theses: Doctorates and Masters
Research has demonstrated the positive effect of exercise on mental health disorders such as anxiety disorder, depression and post-traumatic stress disorder. Studies have also investigated the barriers and motivators that women in particular experience when contemplating the ways in which to engage in physical activity. However, a literature gap exists regarding women who experience anxiety disorder, depression and post-traumatic stress disorder, and the barriers and motivators that they specifically navigate when looking to attend group exercise classes. In this body of research for the award of Master of Medical and Health Science by Research, a scoping review was first conducted …