Digital Commons Network^™

Prognostic And Predictive Value Of Gastric Acid Suppressants In The Eortc 1325/Keynote-054 Randomized Phase Iii Trial Of Pembrolizumab Vs Placebo In Resected Stage Iii Melanoma, Emanuel Bührer, Nina Glassee, Michal Kicinski, Oliver J. Kennedy, Christian U. Blank, Georgina V. Long, Victoria G. Atkinson, Stéphane Dalle, Andrew M. Haydon, Andrey Meshcheryakov, Adnan Khattak, Matteo S. Carlino, Shahneen Sandhu, James Larkin, Susana Puig, Paolo A. Ascierto, Piotr Rutkowski, Dirk Schadendorf, Marye Boers-Sonderen, Anna Maria Di Giacomo, Alfonsus J.M. Van Den Eertwegh, Jean Jacques Grob, Ralf Gutzmer, Rahima Jamal, Alexander C.J. Van Akkooi, Sara Gandini

Research outputs 2022 to 2026

Background: The gut microbiome plays a pivotal role in regulating immunity. Gastric acid suppressants (GAS) are known to alter the gut microbiome and might therefore modify response to immunotherapy in cancer patients. We estimated associations of GAS with recurrence-free survival (RFS) and distant metastasis-free survival (DMFS) in the EORTC 1325/KEYNOTE-054 trial. Methods: Patients with resected stage III melanoma were randomized to receive 200 mg of pembrolizumab or placebo. Pembrolizumab prolonged RFS and DMFS (reported elsewhere). We used Cox models to estimate hazard ratios (HR) and 95 % confidence intervals (CI) for the association between GAS at baseline, and RFS and …

Sustainability Assessment: The State Of The Art In 2026, Alan Bond, Angus Morrison-Saunders, A. John Sinclair

Research outputs 2022 to 2026

Sustainability assessment (SA) has developed over the past three decades as a decision-support process explicitly directing choices towards sustainability. This paper provides an updated state-of-the-art review of SA in 2025, building on the 2012 assessment by Bond, Morrison-Saunders and Pope. We examine progress in theory, practice and process across selected jurisdictions, considering how SA has evolved conceptually and in application. While the volume of academic research on SA continues to grow, practical uptake remains uneven and context-dependent. Key innovations shaping the field include the embedding of sustainability provisions within Canada’s next-generation impact assessment framework, the incorporation of holistic assessment principles …

Work-Integrated Learning As A Landscape Of Practice, Denise Jackson, Karsten E. Zegwaard, David Drewery

Research outputs 2022 to 2026

This article proposes that work-integrated learning (WIL) is a Landscape of Practice (LoP) within the wider higher education ecosystem. It applies concepts from the LoP literature to present a new perspective on WIL programs and ecosystems. It further emphasizes that students are central within the WIL LoP, developing knowledge as they traverse individual communities including industry partners, professional accrediting bodies, careers services, academics, curriculum, and support staff connected to WIL. Additionally, the article highlights the role of higher education institutions in addressing tensions of difference between communities comprising the WIL LoP. The article contributes to the literature on WIL and …

Monitoring Children’S Learner Engagement: The Early Years. A Practical Guide To In School And Learning High Impact Strategies That Build Strong Learner Engagement, Amelia Ruscoe, Leanne Lavina

Research outputs 2022 to 2026

This practical guide presents a high‑impact approach to understanding and monitoring young children’s learner engagement through the integrated use of Dialogic Drawing, LIVE Threads, the Children’s Learner Engagement Monitor, and the Children’s Learner Engagement Planner. These tools were developed using evidence from research with early childhood teachers in response to calls from school leaders and educators for practical, evidence‑informed strategies that strengthen learner engagement. The research underpinning the Children’s Learner Engagement Monitor, funded by AISWA as part of the Preschool Reform Agreement (Australian Government, Department of Education, 2022), addresses four key goals: enabling teachers to gain critical knowledge about children’s …

A Climate Justice Analysis Of Western Australian Government Funding For Collie’S Transition From Coal, 2019-2024, Emma O’Donovan, Naomi Joy Godden

Research outputs 2022 to 2026

The WA Government will close its State owned coal-fired power stations in Collie by 2030, and has committed AU$692 million for Collie’s energy transition. At the request of Wilman and Kaneang Elders and community members, Edith Cowan University’s Centre for People, Place and Planet conducted desktop research about how Collie’s transition funding was allocated between January 2019 and July 2024. This report is a climate justice analysis of publicly-available funding announcements for Collie’s transition during this period to assess whether the distribution of transition resources is equitable and just.

Drawing Sound In Space: Digital Spatial Notation As Constitutive Audiovisuality, Cat Hope

Research outputs 2022 to 2026

This paper examines how the design and realisation of a concert presentation entitled Drawing Sound in Space led to the concept of digital spatial notation. Seven Australian composers were commissioned to create digital scores for an electroacoustic chamber music ensemble, and scores were shared with the audience. The author argues that contemporary digital notation practices enhance live performances of new music by expanding concepts of the audiovisual to include alternative notational approaches engaging with space, creating a ‘spatial notation’. Further, Drawing Sound in Space aimed to transform musicianship and audience experience by offering a more immersive encounter with music notation …

Pfedrag: A Personalized Federated Retrieval-Augmented Generation System With Depth-Adaptive Tiered Embedding Tuning, Hangyu He, Xin Yuan, Kai Wu, Ren Ping Liu, Wei Ni

Research outputs 2022 to 2026

Large Language Models (LLMs) can undergo hallucinations in specialized domains, and standard Retrieval-Augmented Generation (RAG) often falters due to general-purpose embeddings ill-suited for domain-specific terminology. Though domain-specific fine-tuning enhances retrieval, centralizing data introduces privacy risks. The use of federated learning (FL) can alleviate this to some extent, but faces challenges of data heterogeneity, poor personalization, and expensive training data generation. We propose pFedRAG, a novel Personalized Federated RAG framework, which enables efficient collaborative fine-tuning of embedding models to address these challenges. The key contribution is a new Depth-Adaptive Tiered Embedding (DATE) architecture, which comprises a Global Shared Layer, combined using …

A Framework For Understanding The Influence Of The Lifeworld Concept On Small Business Utilisation Of Linkedin, Jalleh Sharafizad, Janice Redmond, Craig Standing, Richard Fulford

Research outputs 2022 to 2026

LinkedIn is a professional platform used as a collaborative tool by small business entrepreneurs to acquire crucial resources needed to sustain and grow their business. However, there is limited research to explain the influence of the lifeworld on entrepreneurs’ LinkedIn use. Using qualitative interviews we address this research gap. The findings reveal evidence of a developing lifeworld within LinkedIn, comprising three key components: culture, social integration, and socialisation. The core small business LinkedIn culture is endorsing and advocating for business brand within a strictly professional ethos, rejecting any deviation from this approach. Social integration is based on strategic actions to …

Accounting For Unmet Needs Resulting From Cancer-Related Cognitive Impairment, Darren Haywood, Alexandre Chan, Raymond J. Chan, Evan Dauer, Haryana M. Dhillon, Ashley M. Henneghan, Maryam B. Lustberg, Moira O’Connor, Janette L. Vardy, Susan L. Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Purpose: Cancer-related cognitive impairment (CRCI) causes a wide range of unmet needs for cancer survivors. It is unknown which clinical, demographic, cognitive, and psychological factors underpin and account for these various unmet needs. This study aimed to (a) identify factors associated with CRCI-related unmet needs, and (b) establish the most pertinent factors that account for CRCI-related unmet needs. Methods: Four hundred and fifty-six (n = 456) cancer survivors responded to a range of demographic and clinical questions, as well as measures of CRCI-related unmet needs (MASCC COG-IMPACT), perceived cognitive impairment (PROMIS-COG), and psychological distress (DASS-21). Descriptive statistics, bivariate correlations, and …

Automated Abdominal Aortic Calcification Scoring From Vertebral Fracture Assessment Images And Fall-Associated Hospitalisations: The Manitoba Bone Mineral Density Registry, Marc Sim, Abadi K. Gebre, Jack Dalla Via, Siobhan Reid, Mohammad Jafari Jozani, Douglas Kimelman, Barret A. Monchka, Syed Zulqarnain Gilani, Zaid Ilyas, Cassandra Smith, David Suter, John T. Schousboe, Joshua R. Lewis, William D. Leslie

Research outputs 2022 to 2026

Abdominal aortic calcification (AAC), a subclinical measure of cardiovascular disease (CVD) that can be assessed on vertebral fracture assessment (VFA) images during osteoporosis screening, is reported to be a falls risk factor. A limitation to incorporating AAC clinically is that its scoring requires trained experts and is time-consuming. We examined if our machine learning (ML) algorithm for AAC (ML-AAC24) is associated with a higher fall-associated hospitalisation risk in the Manitoba Bone Mineral Density (BMD) Registry. A total of 8565 individuals (94.0% female, age 75.7 ± 6.8 years) who had a BMD and VFA image from DXA between February 2010 and …

Child And Family Centred Care: A Three-Phased Principle-Based Concept Analysis, Maggie Zgambo, Julie Blamires, Mandie Foster, Mohammad Al-Motlaq, Therese A. O'Sullivan, Davina Houghton, Evalotte Mörelius

Research outputs 2022 to 2026

Introduction: Despite a growing multidisciplinary interest in the Child and Family Centred Care approach, its meaning remains unclear in extant literature. It is, therefore, crucial to explore, analyse, describe, and clarify the concept of the Child and Family Centred Care approach and its associated terms. Method: A three-phased principle-based concept analysis approach was used to analyse the concept of Child and Family Centred Care. A systematic search of literature was completed using the CINAHL, PsycINFO, Medline, Scopus, and Web of Science databases. Peer-reviewed articles on Child and Family Centred Care, published from inception to 2023 were included if they were …

Co-Opted Directors And Corporate Climate Risk Disclosure, Rashid Zaman, Ummara Fatima, Muhammad Bilal Farooq, Soheil Kazemian

Research outputs 2022 to 2026

Purpose: This study aims to examine whether and how the presence of co-opted directors (directors appointed after the incumbent CEO) influences corporate climate risk disclosure. Design/methodology/approach: This study comprehensively analyses 2,975 firm-year observations of US-listed companies, using ordinary least squares with industry and year-fixed effects. To confirm the reliability of the study results, the authors used several techniques, including propensity score matching, to address potential issues with functional form misspecification, analysed a subset of companies where co-option persisted over two consecutive years to mitigate concerns regarding reverse causality and difference-in-differences estimation, using the cheif executive officer’s (CEO’s) sudden death as …

Design Of An Improved Robust Fractional-Order Pid Controller For Buck–Boost Converter Using Snake Optimization Algorithm, Seyyed Morteza Ghamari, Hasan Molaee, Mehrdad Ghahramani, Daryoush Habibi, Asma Aziz

Research outputs 2022 to 2026

With the increasing complexity of modern power systems, effective control of DC–DC converters has become crucial to ensure stability and efficiency. This paper focuses on optimizing the parameters of a known fractional-order proportional–integral–derivative (FOPID) controller for the control of a DC–DC buck–boost converter. The control of a DC–DC buck–boost converter is achieved using aFOPID approach. The gains of this technique have been enhanced utilizing the snake optimization (SO) algorithm. This converter exhibits unfavourable behaviour due to its non-minimum structure, necessitating a well-regulated controller to guarantee stability. The fractional concept is suggested here to enhance the dynamics of the classical PID …

Does Capital Structure Mediate The Relationship Between Corporate Governance Compliance And Firm Performance? Empirical Evidence From Pakistan, Irfan Haider Shakri, Jaime Yong, Erwei Xiang

Research outputs 2022 to 2026

Purpose: The purpose of this study is to examine how capital structure mediates the effects of corporate governance (CG) compliance on firm performance (FP) in the context of a developing market experiencing significant reforms to its governance landscape. Design/methodology/approach: An index was built to measure firm-level compliance with Pakistan’s code of CG. Several robustness checks were performed, including alternate proxies of dependent and independent variables, using additional control variables and considering the Global Financial Crisis period. To address dynamic effects and endogeneity, several identification strategies were used: a leading dependent variable, fixed effects model, generalised method of moments model and …

Effects Of A Daily, Home-Based, 5-Minute Eccentric Exercise Program On Physical Fitness, Body Composition, And Health In Sedentary Individuals, Benjamin J.C. Kirk, Georgios Mavropalias, Anthony J. Blazevich, Jodie L. Cochrane-Wilkie, Aus Molan, Kazunori Nosaka

Research outputs 2022 to 2026

Purpose: This study examined the effects of a 4-week home-based bodyweight eccentric exercise program, requiring just 5 min daily, on physical fitness, body composition, and both physical and mental health in sedentary individuals.

Methods: Twenty-two sedentary but healthy individuals (4 men, 18 women; 32–69 years) completed a two-week control period followed by a 4-week intervention. The intervention involved daily exercises consisting of 10 repetitions each of chair squats, chair reclines, wall push-ups, and heel drops, including progressions if necessary. Assessments included isometric mid-thigh pull (IMTP), handgrip (HG) strength, push-up and sit-up endurance, sit-and-reach (S&R) flexibility, 3-min step test (3ST), squat …

Exploring The Barriers To Mental Health Help-Seeking Among African Migrants In Australia: A Qualitative Study, Nnaemeka Meribe, Obed Adonteng-Kissi, Kathomi Gatwiri, Lillian Mwanri, Frank Darkwa Baffour, Agness Tembo, Edith N. Botchway-Commey, David Chisanga, Ahmed A. Moustafa, Kerrie E. Doyle, Uchechukwu Levi Osuagwu

Research outputs 2022 to 2026

Background: The health of African migrants in Australia is a largely under-researched topic despite the steadily increasing size of the population and its uniqueness. In particular, few studies have explored the mental health of African migrants in Australia or their utilization of mental health services.

Aims: This study explored the barriers to mental health help-seeking among first-generation African migrants in Australia.

Methods: In this qualitative study conducted using the hermeneutical phenomenological research approach, the purposive sampling method was used to recruit participants. In-depth interviews with participants were undertaken online via Zoom, Teams, and WhatsApp calls. Interviews were recorded and transcribed …

Fostering A Resilient Healthcare System: Supportive Practice Environment Initiatives To Support Nurse And Midwives A Scoping Review, Gemma Doleman, Dianne Bloxsome, Rong Wang, Lisa Whitehead

Research outputs 2022 to 2026

Aim: This scoping review aimed to explore supportive practice environment initiatives that support novice and expert nurses and midwives. Design: Scoping review. Methods: Studies were identified through the electronic databases Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, PsychInfo, Scopus, and Web of Science. Grey literature was searched using GreyNet, National Grey Literature Collection, ProQuest Dissertation and Theses, and Google Scholar. Results: Thirty-one papers met the criteria for inclusion and data extraction. The key concepts identified were the need for adequate staffing and resources, clear and regular communication, managerial presence and engagement in committees and relationship building, celebration …

Gestational Age–Specific Prevalence Of Preeclampsia Among Pregnant Women In Ghana: A Hospital-Based Retrospective Observational Study, Wina Ivy Ofori Boadu, Enoch Odame Anto, Akua Benewaah Asamoah, Ezekiel Ansah, Godfred Yawson Scott, Emmanuel Ekow Korsah, Joseph Frimpong, Valentine Christian Kodzo Tsatsu Tamakloe, Michael Nyantakyi, Agartha Odame Anto, Emmanuel Timmy Donkoh, Kwame Ofori Boadu, Richard Vikpebah Duneeh, Frederick Ayensu, Christian Obirikorang

Research outputs 2022 to 2026

Background: Preeclampsia is responsible for a significant rate of maternal morbidity and mortality worldwide. Gestational age as a risk factor has a significant impact on fetal outcomes in pregnancies affected by preeclampsia. However, to our knowledge, no study has identified the gestational age–specific prevalence of preeclampsia in Ghana. Thus, this study ascertained the gestational age–specific prevalence of preeclampsia as well as its associated factors. Methods: A hospital-based retrospective observational study was conducted by reviewing data collected from the maternal birth register on 619 pregnant women who delivered at the facility from 1st January 2021 to 31st December 2021. Results: Out …

Ghostbusters: Hunting Health Education Within Physical Education, Valeria Varea, Ana Riccetti

Research outputs 2022 to 2026

Purpose: The school subject of physical education (PE) has experienced a “health turn” globally. However, some university undergraduate programs may need to be revised to adequately equip pre-service teachers to teach about health in schools. The aim of this study was to explore the content of an undergraduate university program in PE and what is expected for pre-service PE teachers to teach about health in schools, according to the relevant curricula. Design/methodology/approach: A pragmatic discourse analysis was conducted, using the Argentinean PE school curriculum for primary and secondary schools in the province of Córdoba and the syllabus of an undergraduate …

Investigating The Interplay Of Thermal, Lighting, And Acoustics In Intensive Care For Enhanced Patient Well-Being And Clinical Outcomes, Emil E. Jonescu, Edward Litton, Benjamin Farrell

Research outputs 2022 to 2026

This research explores the interplay among noise levels, thermal conditions, and lighting intensity in an intensive care unit (ICU), focusing on preserving circadian rhythm and promoting nighttime sleep to advance patient-centric care. This investigation assesses lighting levels (Lux), natural versus artificial light ratios, ICU room temperature, and correlations with acoustic data during a field research period and examines the collective impact of patient exposure to sleep linked to delirium and health outcomes, addressing critical gaps in understanding. Findings reveal that noise levels between 60 and 90 dB(A) during patient occupancy exceed sleep disruption thresholds, with daytime averages of 53.6 dB(A) …

Offenders’ Perspectives On Acquisitive Crime Targets And Stolen Goods Disposal Methods, Joseph Clare, Liam Quinn, Natalie Gately, Suzanne Rock

Research outputs 2022 to 2026

This paper examines offenders’ perspectives about acquisitive crime targets and stolen goods markets in Australia that have not been comprehensively reviewed since 2005. Over the last 18 years there have been significant changes in the rates of property crime, reductions in cash usage, and rapid movements to online markets as a disposal outlet, that motivate this updated analysis. In late 2022, n = 107 detainees in a Western Australian police watchhouse were interviewed about their property offending frequency, offence preferences, target selection, disposal methods, and estimated financial return for targeted goods. Results demonstrated (a) meaningful shifts towards shoplifting and away …

Investigating The Acceptability Of Modified Constraint-Induced Movement Therapy Among Stroke Survivors And Carers: A Qualitative Study, Ashan Weerakkody, Erin Godecke, Barby Singer

Research outputs 2022 to 2026

Purpose: To investigate the acceptability of modified constraint-induced movement therapy (mCIMT) among stroke survivors and carers within an early-supported discharge (ESD) service, and to inform further adaptations of the program to enhance acceptability. Methods: Qualitative study within a mixed methods process evaluation of mCIMT implementation. Semi-structured interviews were analysed using reflexive thematic analysis and mapped to the Capability, Opportunity, Motivation- Behaviour (COM-B) model. Results: Fifteen stroke survivors and ten carers participated. Five themes were generated and mapped to the COM-B. Participants attributed functional improvements to the program whilst also encountering several challenges with returning home after stroke (Capability- physical); the …

Experiences Of Exemplary Supervisors Promoting Workplace Dignity Across Social Identity Differences, Emily Joy Aiken

Antioch University Dissertations & Theses

Imagine a workplace where supervisors centered the dignity of each unique individual and sought to honor each person in their wholeness. This type of work environment moves beyond a toxic culture to a space that fosters flourishing, growth, and inclusion. Given that supervisors play an integral role in the experiences of staff members, this study explored the experiences of supervisors in promoting workplace dignity across cultural differences within higher education. With a focus on relational practices and a positive framing, this research sought to develop a nuanced understanding of dignified leadership across social identity differences. Leveraging a constructivist grounded theory …

Adults Drug Court Model's Review: A Case Study, Byron R. Titus

Antioch University Dissertations & Theses

In 1989 Dade County, Florida, the so-called “War on Drugs” was in full swing. As a result, drug courts were created, acting as a diversion program for the many people subsequently caught up in this “war.” Since then, such “specialty courts” have proliferated across the planet. In some cases, local versions have been adopted to adjust to their unique population, culture, risk, and needs. This dissertation is a case study that reviews three Intensive Probation Supervision Programs (IPSP). These IPSPs identify a drug court in their state or country before it becomes a “certified drug court” (now more often referred …

The Survival Of An American Theater: An Intrinsic And Historical Case Study Of The Success Of Arena Stage, Kay Oliver

Antioch University Dissertations & Theses

Arena Stage was founded in 1950 in Washington, DC, by Zelda Fichandler, Tom Fichandler, and Edward Mangum. Today, Arena Stage serves a diverse annual audience of more than 300,000 people. It is the largest theater company dedicated to American plays and playwrights in the country. This study presents a single intrinsic historical case study of Arena Stage to examine the internal organizational structure and leadership dynamics that guided the theater through seven decades of turbulent American history. Arena Stage has provided world-class programming while the nation was grappling with the Vietnam War (1950–1975), Brown v. Board of Education (1954), political …

The Influence Of A Northwestern School District's Equity And Inclusion Initiative On Classroom Teachers' Perceptions Using Culturally Responsive Practices: A Pilot Study Of Selected Principles, Latrica Rich

Antioch University Dissertations & Theses

Racial tensions are high in the United States of America in the 21st century, and hate crimes are on the rise due to political rhetoric and more frequent litigation. This situation challenges current approaches to diversity, equity, and inclusion, commonly known as (DEI). Although these tensions affect many societal areas, the public education system has seen particularly dramatic changes as the nation's diversity grows. This shift has invoked the first moves to adapt culturally relevant practices to promote inclusion and belonging in response to evolving classroom dynamics. This study examined some of the significant issues surrounding the implementation of cultural …

Reassessing Criminogenic Risk: How Trauma-Informed Assessment More Accurately Predicts In-Prison Behavior Than Traditional Models, Bree E. Derrick

Antioch University Dissertations & Theses

Criminogenic risk-needs assessment is the cornerstone of recidivism reduction models in the correctional sector. Despite decades of using criminogenic risk-need tools, recidivism outcomes remain stubbornly high in the U.S. This non-traditional dissertation explored how traditional criminogenic assessments could be improved with the addition of measures of childhood adversity and maltreatment. This study found that the prevalence of ACEs was significantly greater in an adult prison population of 1,522 in a rural, western state than in the general public. Utilizing logistic regression, this research also found that ACEs were better predictors of in-prison misconduct than traditional criminogenic risk-needs assessments, although traditional …

Mirrors Of The Reel: Black Women's Identity In American Cinema (2009-2024), Melanie-Penny Harrison

Antioch University Dissertations & Theses

This study investigates whether white supremacy structures, embodied in Hollywood’s predominantly white leadership, drive negative portrayals of Black women in 31 mainstream American films from 2009 to 2024. Employing a mixed-methods approach—quantitative content analysis, qualitative content analysis (QCA), and narrative methodology—I code portrayals for racism, patriarchy, heterosexism, colorism, and internalized racism, classifying them as progressive (e.g., empowered roles), regressive (e.g., subservient stereotypes), or hybrid. Guided by Critical Race Theory and intersectionality, the analysis examines narrative structures, character agency, symbolism, and dialogue to uncover intersectional patterns (e.g., race, gender, class) across three periods: 2009–2013, 2014–2018, and 2019–2024. Across these periods, cultural …

A Mandate For Healing: A World War Ii Vet Meets A Vietnam Vet In The Screenplay, Chinook With An Essay On War Screenplay Research, Buz Ecker

Antioch University Dissertations & Theses

Chinook is an original screenplay about a Vietnam vet with PTSD who meets a World War II vet in a VA Home, and the screenplay takes one afternoon to unfold. This dissertation explains how Chinook came to be, with all of the processes undertaken. It begins with an introduction about the characters in the screenplay and who these characters are based on. There are several books, movies, and articles contained in this section to make the characters, events, and flashbacks of what actually happened in World War II and Vietnam. The best resources were conversations with actual veterans from either …

Innovating Chaplaincy Education: Integrating Nonreligious Spiritual Care Interventions To Serve A Diverse Patient Population, Dianne Dragon

Antioch University Dissertations & Theses

The transformation to the curriculum taught in chaplain training in Clinical Pastoral Education (CPE) will now address the spiritual needs of a more diverse, nonreligious, and interfaith population in the United States. Historically rooted in religious frameworks, CPE curricula are evolving to incorporate non-religious spiritual care interventions and promote research literacy among chaplains. This dissertation study uses descriptive analysis to present a study surveying CPE educators across over 300 U.S. based CPE centers to explore teaching practices and adaptation strategies. Findings reveal that integrating evidence-based methods and interdisciplinary collaboration is key to addressing inclusivity and professional competency in chaplaincy. By …