Digital Commons Network^™

Antimicrobial Activity Of Silver Nanoparticles Synthesized Using Thai Herbal Extracts, Charuwan Pradabsang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Synthesis of silver nanoparticles (SNP) using Thai herbal plants, namely Garcinia cowa Roxb. ex Choisy (S1), Boesenbergia rotunda (L.) Mansf. (S2), Curcuma mangga Valeton & Zijp (S3), Momordica charantia L. forma abbreviata (Ser.) W. J. de Wilde & Duyfjes (S4), Persicaria odorata (Lour.) Soják (S5), Litsea elliptica Blume (S6), Gnetum gnemon Linn. var. tenerum Markgr (S7), Phaleria macrocarpa (Scheff.) Boerl. (S8), Salacia chinensis Linn. (S9) and Brachypterum scandens (Roxb.) Miq. (S10), is considerably economical and safe. Plants and preparation methods can affect properties and bioactivity such as controlled temperature of SNP. This study aimed to assess the ability of aqueous …

The Development Of Surveillance And Monitoring Tools For Pharmaceutical Supply Chain Management System For Public Health Emergencies, Kakanang Tosanguan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Thailand frequently experiences public health emergencies (PHEs) that severely disrupt pharmaceutical supply chain (PSC) management. This study addresses the urgent need for a specialized assessment tool to identify system weaknesses, support timely risk management, and enhance national preparedness planning.Methods: Utilizing a sequential exploratory mixed-methods design (July 2022–July 2024), the study began with a scoping review to identify existing frameworks. Following this, in-depth interviews with 36 key stakeholders synthesized conceptual domains. The draft tool underwent rigorous content validity assessment by 63 experts and was then pilot tested with 62 participants to confirm reliability (Cronbach’s alpha).Results: The evidence synthesis resulted in …

Chinese Students’ Mothers In Thailand: Transnational Education And Migration, Shan Li

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research focuses on Chinese mothers accompanying their children to study in Thailand, exploring their life experiences, identity transformation, and social adaptation within this transnational educational migration phenomenon. A mixed research method (questionnaire survey and interviews) was employed, systematically analyzing data from 151 questionnaires and 13 interviewed mothers. Results show that these accompanying mothers generally possess high levels of education and economic capability, with most abandoning their original professions for their children's education, forming a transnational family structure of husband remaining in China, wife accompanying her child in Thailand. While this model reinforces traditional gender roles, it also encourages women …

Evaluation Of User Experience And Usability Of Organization Super App, Ananya Kumhan

Chulalongkorn University Theses and Dissertations (Chula ETD)

The digital transformation of organizations in Thailand has accelerated the development of internal systems that streamline workflows and improve accessibility to organizational information. Financial institutions, which operate with multiple fragmented systems, have increasingly adopted Enterprise SuperApps as a centralized platform that combines internal services such as corporate news, leave requests, employee directories, resource information, and meeting room reservations into a single application. However, usage statistics in several organizations indicate that continuous adoption remains relatively low. Many employees rely on alternative channels or use only selected features, reflecting challenges in user experience (UX) and usability. This study aims to evaluate the …

Partial Group Divisible 3-Designs, Apiwat Peereeyaphat

Chulalongkorn University Theses and Dissertations (Chula ETD)

We introduce a generalization of group divisible 3-designs, 3-GDDs, with two groups and two indices. A partial group divisible 3-design, 3-PGDD(gı + g2, k; A, (21, 112), is an ordered pair (GrU G2, B) where G, and G2 are disjoint finite sets called groups) of size g1 and 92, respectively; and B is a collection of k-subsets (called blocks) of G, UG, such that every 3-subset of G; occurs in exactly 1 blocks in B, and every i elements of G and j elements of G2 occur together in exactly Mig blocks in B for i. i € (1,2} and …

Development Of Potentiometric Aptasensor For The Detection Of Escherichia Coli, Chalinee Auanphui

Chulalongkorn University Theses and Dissertations (Chula ETD)

A potentiometric aptasensor was developed for the rapid and label-free detection of Escherichia coli (E. coli), a major food- and water-borne pathogen of public health concern. The sensor utilized a laser-induced graphene (LIG) electrode fabricated by laser engraving on a polyimide substrate, followed by modification with an ion marker, coating with a carboxylated poly(vinyl chloride) (PVC–COOH) membrane, and immobilization of an E. coli-specific aptamer. The remaining surface was blocked with bovine serum albumin (BSA) to minimize nonspecific adsorption. Detection was based on changes in ion exchange between the ion marker and membrane upon the specific binding of E. coli to …

Evaluation Of Heavy Metal Bioaccumulation And Growth In Hemp From Chicken Manure, Vermicompost, And Wastewater Sludge With Biochar And Health Risk Assessment, Chutiphan Sangsoda

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hemp (Cannabis sativa L.) has become an economically valuable crop with a wide range of benefits. To promote more sustainable agricultural systems, the use of recycled substrates has increasingly replaced traditional fertilizers. However, substrates such as dry chicken manure, vermicompost, and wastewater sludge (WWS) combined with biochar often contain heavy metal contaminants, which may pose health risks through exposure to hemp. This study investigated three cultivars Rosella, Superwoman S1, and Red Robin over a 120-day period. The objectives were: (1) to compare the effects of dry chicken manure, vermicompost, and wastewater sludge (with and without biochar) on soil nutrient quality …

Removal Of Antibiotics Under Visible Light By Using C,N-Tio2 Incorporated Into Magnetite Mesoporous Silica Composites, Dwita Widyawati

Chulalongkorn University Theses and Dissertations (Chula ETD)

Water contamination, particularly from antibiotics such as ciprofloxacin, is a significant environmental challenge necessitating the development of new remediation solutions. A promising technique for eliminating CIP from the environment is photocatalysis. The synthesis of C,N-doped TiO2 embedded within magnetite mesoporous silica (MSI) composites is prepared to serve as a promising semiconductor catalyst for photodegradation under visible illumination. Tetrabutyl titanate (TBOT), glucose, and urea are used as precursors in the sol-gel synthesis process, which controls elemental ratios to produce a unique mesoporous composite material intended to improve antibiotic photodegradation in the presence of visible light. Comparisons showed significant differences between capped …

Assessment Of Rainfall Anomaly In Thailand Under Enso By Inception Time For Classification Model, Hazlamee Benjawong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study provides a comprehensive assessment of rainfall over Thailand during the El Niño-Southern Oscillation (ENSO) event using 41 years of monthly data (1982-2022) from meteorological stations, including total rainfall, average temperature, average wind speed, and average wind direction. The data were processed using Python by estimating spatially dependent monthly variables using inverse distance weighting. Total rainfall during ENSO events lasting more than two years was estimated by calculating ZSI12and analyzing the variable's significance using an inception time for classification model. The spatial total rainfall estimation results show that the distribution of total rainfall for normal, El Niño, and La …

Effect Of Single Screw Extrusion Process Parameters On Gel Formation And Properties In Polycaprolactone Films, Kitthanya Ritthichai

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research focuses on the production of polycaprolactone (PCL) films using the commercial grade CAPA 6800 through a continuous single-screw extrusion process. This method serves as an alternative to conventional solution-based film fabrication that requires solvents and chemical reagents. The effects of processing temperature (80–120 °C), screw design (mixing screw and plain screw), and extruder-barrel cooling system (water-cooled and air-cooled) on film quality, gel formation, thermal properties, and mechanical properties of PCL films were investigated. Based on the processing of high-purity PCL pellets, the results indicate that the processing temperature, screw design, and barrel-cooling system did not affect the chemical …

Blocfog : Enhanced Transactional Data Encryption Via Fog Computing And Blockchain, Leon Wirz

Chulalongkorn University Theses and Dissertations (Chula ETD)

Protecting Personally Identifiable Information (PII) in financial transactions presents ongoing challenges, particularly in achieving a balance between strong security, fine-grained access control, and system efficiency. Existing approaches often rely on complex cryptographic operations that strain end-user devices or lack the flexibility needed for decentralized environments. Although blockchain provides advantages such as auditability and tamper resistance, its use is often limited by high computational costs and latency. This research proposes an efficient and scalable access control framework that integrates Ciphertext-Policy Attribute-Based Encryption (CP-ABE) with a lightweight fog computing layer. The system is designed to offload heavy cryptographic tasks from end users …

Improving Chinese Hate Speech Detection With Bert-Fasttext Fusion And Bert-Bilstm Fusion, Methini Ma

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hate speech detection is an essential technique in the online environment, especially on social media platforms. This technique helps to create a safer space and reduce the risk of real-world harm. In Chinese, this task is particularly challenging because of unique linguistic structures and the frequent use of indirect expressions, sarcasm, homophones, character variants, and abbreviations. This study investigates how to improve Chinese hate speech detection by combining BERT with FastText and BERT with BiLSTM. There are six model variants that are configured: frozen BERT and fine-tuned BERT, each further extended with either FastText sentence embeddings or a clause-level BiLSTM. …

Evaluation Of Soil Erosion In The Middle Yom River Basin, Passapong Paentong

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aims to assess soil erosion in the Middle Yom River Basin and analyze the spatial relationships between erosion and its influencing factors using the Revised Universal Soil Loss Equation (RUSLE) in combination with Ordinary Least Squares (OLS) regression analysis. The analysis considers five principal RUSLE factors: rainfall erosivity (R), soil erodibility (K), topography (LS), cover management (C), and support practices (P), under both normal and heavy rainfall scenarios for the years 2010, 2015, and 2020. The results indicate that under normal rainfall conditions, most areas experienced low to moderate soil loss (0–5 tons/rai/year). Under heavy rainfall conditions, the …

Gel Based Sensing Platforms For Ammonia Detection, Patita Salee

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research focuses on the development of two biopolymer-based colorimetric platforms for ammonia detection in environmental water and gaseous samples. To detect ammonia in water samples, an agarose hydrogel membrane containing salicylate, hypochlorite, and sodium nitroprusside was incorporated into a flow analysis system to perform the Berthelot reaction within the gel. Ammonium in the sample was converted to monochloramine in an alkaline reagent stream, and its subsequent interaction with the sensing membrane yielded an indosalicylate blue chromophore, causing the gel to change from pale yellow to green–blue as the ammonia concentration increased. Under the optimal operating conditions, the method provided …

Comprehensive Analysis Of Environmental Particulate Matter: Chemical Composition And Microbial Assessment, Uyen T. L. Le

Theses and Dissertations (Comprehensive)

Rapid industrialization and population growth have contributed to a decline in air quality, with particulate matter (PM) posing particular concern. PM originates from both natural and human sources and often contains toxic chemicals and microorganisms, including potential pathogens. Inhalation of PM is linked to respiratory and cardiovascular diseases, underscoring the need to characterize better its chemical and biological composition in understudied region - Waterloo, Ontario, Canada. The present thesis is a culmination of three main parts. Part 1 will describe the use of the dithiothreitol (DTT) assay to quantify the oxidative potential of PM through DTT consumption of redox-active field …

More Than Meets The Eye: A Phenomenological Study Of Self-Concept, Identity, And Meaning-Making In Adults With Acquired Vision Loss, Melinda M. Szilva

Theses and Dissertations (Comprehensive)

The qualitative research project examines the lived experience of acquired vision loss in adulthood and its impact on the way participants see themselves and the world around them, both sensorially and metaphorically. The research question, “What are the lived experiences of adults with acquired vision loss as they relate to identity and conceptions of self?” is informed by the researcher’s clinical practice as a psychotherapist in a low vision clinic. The dissertation includes a literature review focussed on the psychosocial aspects of vision loss to provide insight into the intended population and context for the study. Data for the phenomenological …

A Dance Of War Or Love: Applying A Gendered Lens On The Lived Experiences Of Women Social Entrepreneurs In Nigeria, Grace C. Ihejiamaizu

Theses and Dissertations (Comprehensive)

This study explores the lived experiences of Nigerian women social entrepreneurs, using a qualitative methodology rooted in yarning circles, a culturally respectful, relational approach that foregrounds storytelling and co-construction of knowledge. Through this method, the research examines how these women navigate the intersections of gender, culture, power, and purpose within highly patriarchal and institutionally constrained environments.

The findings assert that Nigerian women social entrepreneurs are not static actors driven by fixed motivations, but dynamic changemakers whose goals shift as they gain access to resources, legitimacy, and social capital. The Cycle of Privilege framework helps us understand this evolution as an …

Terpenes Mitigate Thc-Induced Working Memory Deficits: Behavioural Evidence Of The Entourage Effect Using A 2-Component Operant Memory Task, Lara Mitchell

Theses and Dissertations (Comprehensive)

Most research on cannabis and cognitive function has focused on delta-9-tetrahydrocannabinol (THC). However, this approach overlooks the complex chemical composition of cannabis products consumed by the public, which often includes cannabidiol (CBD) and various terpenes. These additional constituents may interact with THC to modulate its effects, a phenomenon known as the entourage effect. While this theory has gained traction, experimental evidence for the cognitive impact of terpenes in combination with THC remains limited. This study aimed to assess whether terpenes can mitigate THC-induced cognitive deficits using a 2-Component Operant Memory task. Male Sprague-Dawley rats received intraperitoneal injections of either …

Crime Modeling Using An Integrated Cnn–Lstm Architecture With Embedded Self-Excitation, Pawandeep Kaur

Theses and Dissertations (Comprehensive)

It is often assumed that natural phenomena occur randomly over time. However, careful analysis reveals that these events typically form some series or sequences and exhibit distinctive temporal patterns. These patterns are not exclusive to nature. They also appear in human activities, often studied under the concept of bursty human dynamics. The statistical methods analyzing bursty human dynamics not only capture overall trends or seasonality but also explore how past events influence future ones. It makes the analysis more realistic and the results more closely aligned with reality. Bursty human dynamics can be studied at two levels: the individual level …

The Echoes Of Heartbreak: Shaping Confidence In Future Relationships Through Metaperceptions Of The Past, Anika P. Patychuk

Theses and Dissertations (Comprehensive)

Romantic relationship dissolution can be deeply destabilizing. Existing research has documented the emotional and psychological consequences of breakups but has rarely examined how these experiences shape subsequent relationship functioning. While breakups often trigger self-protective responses that can inhibit future relationship formation, individuals may also derive valuable relational insights from these experiences. The present research examined whether perceiving past romantic relationships as valuable sources of relational knowledge (epistemically valuable) enhances confidence in future romantic pursuits. I propose that perceiving past relationships as high (vs. low) in epistemic value encourages confidence in future romantic pursuits. I tested this hypothesis in three experimental …

The Body’S “Why?”: Therapists’ Embodied Approaches To Meaning-Making In Trauma And Complex Ptsd, Tanya D. Rock

Theses and Dissertations (Comprehensive)

The challenge of finding meaning in trauma is one that has inspired conversations in psychotherapeutic circles as well as amongst theologians and philosophers. Finding meaning following trauma has been positively associated with growth following the traumatic incident and has been labelled as critical to the progression of healing (Herman, 1992). This study aims to examine the role therapists play in meaning-making with clients who have experienced trauma. The research question is “how do therapists handle meaning of life challenges with traumatized clients?” Ten experienced therapists participated in this qualitative, phenomenological study. Key findings included common therapist responses to client’s “why?” …

Integrating Indigenous Values And Community Strengths To Achieve Indigenous Food Sovereignty And Community Well-Being In The Ka’A’Gee Tu First Nation, Northwest Territories, Jennifer K. Temmer

Theses and Dissertations (Comprehensive)

Northern Indigenous communities face disproportionate impacts from interconnected challenges related to climate change, food security, health, and cultural preservation, that threaten traditional food systems and practices. While there is a growing recognition of the importance of community-driven solutions, existing frameworks fail to integrate Indigenous values and local priorities effectively. This research addresses this gap by exploring how the Ka’a’gee Tu First Nation (KTFN) is responding to these crises through climate change adaptation efforts focused on food system sustainability as a pathway to self-sufficiency and community well-being. To contribute to these efforts, this dissertation uses Participatory Action Research to facilitate community-driven …

Feeling Blue: The Effects Of Blue Light Exposure On Reproduction And Physiology In Drosophila Melanogaster, Laura Hampel

Theses and Dissertations (Comprehensive)

Blue light, the wavelengths ranging from ~400-500 nm, is emitted from the sun and more recently, by artificial lights including those in technology. In humans, prolonged exposure to blue light has been consistently linked to circadian rhythm disruption and retinal damage, and has also been associated with changes in neurodegeneration, aging, mortality, and oxidative stress in model organisms. This thesis explores the multifaceted effects of blue light exposure through two independent but complementary approaches. An initial rapid review of the current state of knowledge on blue light induced oxidative stress in humans was conducted. This revealed that the most studied …

Geographies Of Trauma And Healing: Resistance, Resilience, ‘Ustawi Wa’, And The Lived Experiences Of African Women Refugees From The Ehagl Region In Canada, Rosemary Njeri Kimani-Dupuis Dr., Rosemary Kimani-Dupuis

Theses and Dissertations (Comprehensive)

This dissertation explores the lived experiences of African women refugees from the East and Horn of Africa and Great Lakes (EHAGL) region resettled in Ontario, Canada, with particular focus on the complex intersections of trauma, resilience, and healing within global refugee governance. It asks: How do the gendered and spatial dynamics of refugee protection and Canadian settlement systems sustain structural violence against African women refugees, and how do their transnational experiences challenge and reshape dominant frameworks of care, well-being, and institutional response?

Through a multi-scalar analysis—macro (legal governance frameworks), meso (institutional actors), and micro (women’s narratives)—the study explores how trauma …

Functional Design Of Dissymmetric Ligands For Coordination Systems, Kaitlyn R. Brown

Theses and Dissertations (Comprehensive)

Herein, the functional design of dissymmetric ligands for coordination systems is explored with a focus on their synthesis and structural characterization. The design strategy of these ligands incorporates the ability to coordinate both metal cations and anions along with a ligand site for other functionalization. Their synthesis, structural and other characterization, Hirshfeld surface analysis, and some metal-coordinated complexes are discussed. Chapter 1 introduces supramolecular and coordination chemistry, along with relevant literature that supports this research and outlines the thesis objective. Chapter 2 investigates the hydrogen bonding of a dissymmetric pyrimidine thioether ligand in its neutral form, water solvate, protonated nitrate …

Nature For All? Assessing Equitable Public Access To National Urban Parks In Canada: A Comparative Analysis, Andrew Tenute

Theses and Dissertations (Comprehensive)

The number of health challenges is rising both globally and in Canada. Research consistently shows that time spent in nature can mitigate some of these health challenges, offering significant mental, physical, and well-being benefits. Parks and protected areas in Canada, including the expansion of the National Urban Park (NUP) program by Parks Canada, provide valuable opportunities for nature-based engagement. However, access to these spaces is unjust, as many individuals face structural, intrapersonal, and interpersonal constraints. While prior studies have explored the motivations and well-being outcomes of women and Black, Indigenous, and People of Colour (BIPOC) individuals, there remains a limited …

The Experiences Of Mothering With An Intimate Partner Violence-Related Brain Injury, Emily L. Sebben Miss

Theses and Dissertations (Comprehensive)

One in three Canadian women will experience intimate partner violence (IPV) in their lifetime, and 75% of them have a probable brain injury (BI) (Haag et al., 2022). Despite the recent growth of IPV-BI research, many survivors remain undiagnosed and many aspects remain unexplored. The experiences of being a mother with an IPV-related BI has been left untold. These gaps leave frontline workers with little guidance in supporting survivors who are specifically mothers. This research reports on a qualitative study exploring the lived experiences of mothering with an IPV-BI. The study uses a constructivist worldview and hermeneutic phenomenology to amplify …

Exploring The Shadows: How Taylor Swift's Music Embodies Dark Sound As A Popular Music Artist, Kristyn E. Cole

Theses and Dissertations (Comprehensive)

To challenge the conceptual matter of “dark sound”, this major research paper centers around the popular music artist, Taylor Swift to demonstrate an overarching feminist wisdom in an alternative style of music to identify how Taylor Swift presents and embodies qualities of “dark sound”. Research done by D. Ferrett, Theodor Adorno, Roland Barthes and Paul C. Jasen are used to examine her popular music, and its intersections and influence on our culture and society. Using multimodal critical discourse analysis, this research paper discusses three of Swift’s songs; “willow” (evermore, 2020) for her sound, All Too Well: The Short …

The Progressive Potential Of The Horror Arg: A Digital Ethnographic Analysis Of Instagram Account Sabrinamiller230, Matthew N. Wiebe

Theses and Dissertations (Comprehensive)

Alternate reality games (ARGs) are transmedia games that exist and operate utilizing a number of digital communication platforms. These games see players employing their digital literacy skills in order to solve narrative puzzles and craft theories with other ARG players – through engaging with the alternate reality fiction presented to them. sabrinamiller230 is a horror themed ARG that takes the appearance of an Instagram profile and presents players with a speculative alternate reality world featuring an alien who critiques humanity’s many injustices. This research paper seeks to address a key problem regarding the lack of digital ethnographic studies of ARG …

Construction Techniques For Linear Realizations Of Multisets With Small Support, M. A. Ollis

Emerson Authors, Researchers, & Creators

The Buratti-Horak Rosa Conjecture is a problem in graph theory asking when we can find a Hamiltonian path in the complete graph that has various properties to do with edge lengths. In this paper, we use constructive methods to show that the conjecture is true for various parameter sets where it was previously unknown.