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2025

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Under The Sea And Into The Future With Darwin, Verne, & Wells: Evolutionary Ideas In Early Science Fiction Literature And Atomic Age Adaptations, Suzette K. Forston Aug 2025

Under The Sea And Into The Future With Darwin, Verne, & Wells: Evolutionary Ideas In Early Science Fiction Literature And Atomic Age Adaptations, Suzette K. Forston

Theses and Dissertations

In the latter half of the nineteenth century, Charles Darwin's theories challenged traditional ways of thinking about the world so dramatically that his writings inspired the formation of a new genre: science fiction. Two pioneering authors, Jules Verne and H. G. Wells drew from Darwin's writings in their classic novels, 20,000 Leagues Under the Seas (1870) and The Time Machine (1895). Though the two authors are often compared because they were both early science fiction authors, they approached Darwinian theory in different ways. Verne uses a more extrapolative approach and focusing on specific details of Darwin's texts to tell a …


Gamete Size Is Essential For Understanding Sex And Sexual Selection In Humans, Animals, Plants, And Algae But Configurations Of Sex-Linked Traits Are Practically Important For Understanding Sex, David A. Frederick Aug 2025

Gamete Size Is Essential For Understanding Sex And Sexual Selection In Humans, Animals, Plants, And Algae But Configurations Of Sex-Linked Traits Are Practically Important For Understanding Sex, David A. Frederick

Psychology Faculty Articles and Research

"First, I briefly highlight recent discussions of sex and how they contrast with a gametic central understanding of sex in the executive order. I then provide some background on why gametes have been central to defining sex across species in evolutionary biological sciences. Understanding this perspective is important because it helps understand the competing frames people are using when they talk of sex as binary instead of as a spectrum or a multidimensional configuration of traits. The gametic central framing is essential for understanding sex and sexual selection across species, whereas the multidimensional configuration framing is practically useful in medical, …


Tracing Sars-Cov-2 Clusters Across Local Scales Using Genomic Data, Leke Lyu, Mandev Gill, Guppy Stott, Sachin Subedi, Cody Dailey, Gabriella Veytsel, Magdy Alabady, Kayo Fujimoto, Ryker Penn, Pamela Brown, Roger Sealy, Justin Bahl Aug 2025

Tracing Sars-Cov-2 Clusters Across Local Scales Using Genomic Data, Leke Lyu, Mandev Gill, Guppy Stott, Sachin Subedi, Cody Dailey, Gabriella Veytsel, Magdy Alabady, Kayo Fujimoto, Ryker Penn, Pamela Brown, Roger Sealy, Justin Bahl

Faculty, Staff and Student Publications

A quantitative understanding of local transmission dynamics is essential for designing effective prevention strategies. In this study, we developed a computational workflow to identify viral introductions and trace locally circulating clusters. We analyzed over 26,000 SARS-CoV-2 genomes and their associated metadata, collected between January and October 2021, to explore introduction and local dispersal patterns in Greater Houston, a major metropolitan area known for its demographic diversity. Our analysis identified more than 1,000 independent introduction events, resulting in clusters of varying sizes. The majority of introductions originated from domestic sources, while international introductions occurred earlier and were associated with larger cluster …


Molecular Inflammatory Expression Profiles Associated With The Frequency Of Pain In Individuals With Sickle Cell Disease, Lana Mucalo Katunaric, Shuang Jia, Ashima Singh, Mark F. Roethle, Julie A. Panepinto, David C. Brousseau, Martin J. Hessner, Amanda M. Brandow Aug 2025

Molecular Inflammatory Expression Profiles Associated With The Frequency Of Pain In Individuals With Sickle Cell Disease, Lana Mucalo Katunaric, Shuang Jia, Ashima Singh, Mark F. Roethle, Julie A. Panepinto, David C. Brousseau, Martin J. Hessner, Amanda M. Brandow

Department of Pediatrics Faculty Papers

Pain is the most common complication of sickle cell disease (SCD). The underlying biology of SCD pain is not well understood, which is a barrier to novel, effective analgesic and preventive therapies. A wide variability in the phenotypic expression of pain exists among individuals with SCD, despite the inheritance of a similar defective hemoglobin gene. This interindividual pain variability further complicates the ability to understand the biology and effectively treat pain. We sought to discover a biological signature comprising differentially expressed genes unique to SCD that could differentiate between individuals with varied pain frequency. We conducted plasma-induced transcription analysis from …


Assessing The Muc5b Promoter Variant In A Large Cohort Of Systemic Sclerosis-Associated Interstitial Lung Disease, Carlos Rosa-Baez, Carlos Rangel-Pelaez, Inmaculada Rodriguez-Martin, Martin Kerick, Alfredo Guillen-Del-Castillo, Carmen P Simeon-Aznar, José Luis Callejas, Alexandre E Voskuyl, Alexander Kreuter, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Nicolas Hunzelmann, Jeska K De Vries-Bouwstra, Ariane L Herrick, Yannick Allanore, Lorenzo Beretta, Maureen D Mayes, Christopher P Denton, Shervin Assassi, Javier Martin, Marialbert Acosta-Herrera Aug 2025

Assessing The Muc5b Promoter Variant In A Large Cohort Of Systemic Sclerosis-Associated Interstitial Lung Disease, Carlos Rosa-Baez, Carlos Rangel-Pelaez, Inmaculada Rodriguez-Martin, Martin Kerick, Alfredo Guillen-Del-Castillo, Carmen P Simeon-Aznar, José Luis Callejas, Alexandre E Voskuyl, Alexander Kreuter, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Nicolas Hunzelmann, Jeska K De Vries-Bouwstra, Ariane L Herrick, Yannick Allanore, Lorenzo Beretta, Maureen D Mayes, Christopher P Denton, Shervin Assassi, Javier Martin, Marialbert Acosta-Herrera

Faculty, Staff and Student Publications

Objective: The common gain-of-function variant rs35705950, located in the promoter of MUC5B gene, has been strongly associated with interstitial lung diseases (ILDs) of different aetiology, such as idiopathic pulmonary fibrosis (IPF) and rheumatoid arthritis-associated ILD (RA-ILD). In this study, we aimed to investigate the association of this variant and its nearby single nucleotide polymorphisms (SNPs) in the largest cohort of systemic sclerosis-associated ILD (SSc-ILD) to date.

Methods: Samples were collected from blood/saliva, followed by DNA extraction and genotyping using SNP arrays. Data for rs35705950 and additional 903 variants within 100 Kb were obtained using genomic imputation. Subsequently, we tested their …


Extracellular Vesicles For Clinical Diagnostics: From Bulk Measurements To Single-Vesicle Analysis, Hai Linh Tran, Wenshu Zheng, David A Issadore, Hyungsoon Im, Yoon-Kyoung Cho, Yuanqing Zhang, Dingbin Liu, Yang Liu, Bo Li, Fei Liu, David Tai Wai Wong, Jiashu Sun, Kun Qian, Mei He, Meihua Wan, Yong Zeng, Ke Cheng, Tony Jun Huang, Daniel T Chiu, Luke P Lee, Lei Zheng, Andrew K Godwin, Raghu Kalluri, Steven A Soper, Tony Y Hu Aug 2025

Extracellular Vesicles For Clinical Diagnostics: From Bulk Measurements To Single-Vesicle Analysis, Hai Linh Tran, Wenshu Zheng, David A Issadore, Hyungsoon Im, Yoon-Kyoung Cho, Yuanqing Zhang, Dingbin Liu, Yang Liu, Bo Li, Fei Liu, David Tai Wai Wong, Jiashu Sun, Kun Qian, Mei He, Meihua Wan, Yong Zeng, Ke Cheng, Tony Jun Huang, Daniel T Chiu, Luke P Lee, Lei Zheng, Andrew K Godwin, Raghu Kalluri, Steven A Soper, Tony Y Hu

Faculty, Staff and Student Publications

Extracellular vesicles (EVs) play a crucial role in intercellular communication, signaling pathways, and disease pathogenesis by transporting biomolecules such as DNA, RNA, proteins, and lipids derived from their cells of origin, and they have demonstrated substantial potential in clinical applications. Their clinical significance underscores the need for sensitive methods to fully harness their diagnostic potential. In this comprehensive review, we explore EV heterogeneity related to biogenesis, structure, content, origin, sample type, and function roles; the use of EVs as disease biomarkers; and the evolving landscape of EV measurement for clinical diagnostics, highlighting the progression from bulk measurement to single vesicle …


Computational And Mathematical Modeling Of Microbial Community And Host Responses To Microbiota-Directed Complementary Foods Administered To Children With Acute Malnutrition., Steven J. Hartman Aug 2025

Computational And Mathematical Modeling Of Microbial Community And Host Responses To Microbiota-Directed Complementary Foods Administered To Children With Acute Malnutrition., Steven J. Hartman

Arts & Sciences Graduate Student Theses and Dissertations

Globally, millions of children suffer from undernutrition, with stunting affecting 150 million and wasting nearly 50 million under five years old. Current interventions have shown limited effectiveness in mitigating long-term consequences such as stunted growth, cognitive deficits, and immune dysfunction. Through this body of work, I investigated the efficacy of a microbiota- directed complementary food (MDCF-2) as a next generation therapeutic food to combat childhood stunting. Across two randomized controlled trials involving Bangladeshi children with either moderate acute malnutrition or post-severe acute malnutrition, MDCF-2 significantly outperformed standard ready-to-use supplementary foods (RUSF), leading to significantly improved ponderal and sustained linear growth …


Re: Revised Draft Final Insufficiently Reclaimed Sites Field Sampling And Investigation Plan (Fsp): Bres No. 120 – Bonanza Dump, Mike Mcanulty Aug 2025

Re: Revised Draft Final Insufficiently Reclaimed Sites Field Sampling And Investigation Plan (Fsp): Bres No. 120 – Bonanza Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Jefferson Et Al. Reply, Osmat Jefferson, W. Nicholson Price Ii, S. Sean Tu, Saurabh Vishnubhakat, Arti K. Rai Aug 2025

Jefferson Et Al. Reply, Osmat Jefferson, W. Nicholson Price Ii, S. Sean Tu, Saurabh Vishnubhakat, Arti K. Rai

Articles

Notwithstanding Amgen’s strenuous objections, the core premise of our article should be uncontroversial to most policy analysts: biosimilar firms that simply want to manufacture an originator biologic in the manner it was manufactured at the time of US Food and Drug Administration (FDA) approval should be able to enter the market expeditiously once valid manufacturing (and other valid patents) that legitimately cover the ‘at approval’ biologic have expired. Our core premise relies on the widely accepted values of patent validity and notice. Instead of expensive litigation discovery fights over such ‘at approval’ issues, of the sort Amgen itself has spearheaded …


Six New Members Join Iwu Board Of Trustees, Julia Perez Aug 2025

Six New Members Join Iwu Board Of Trustees, Julia Perez

Press Releases 2020-2029

No abstract provided.


Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Mdd, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Mark A Bellgrove, Vivek Benegal, Robert J Blair, Laura Blanco-Hinojo, Ole Jonas Boeken, Joscha Böhnlein, Sven Bölte, Linda M Bonnekoh, Daniel Brandeis, Rodrigo A Bressan, Fabian Breuer, Willem B Bruin, Jan K Buitelaar, Katie L Burkhouse, Monica E Calkins, Marta Cano, Narcis Cardoner, Hui Chen, Xianliang Chen, David R Coghill, Olivier F Colins, Colm G Connolly, Michael C Craig, Kathryn R Cullen, Udo Dannlowski, Christopher G Davey, Andrea Dietrich, Daifeng Dong, Christine M Freitag, Thomas Frodl, Liesbet Goossens, Dominik Grotegerd, Raquel E Gur, Ruben C Gur, Jan Haavik, Cindy C Hagan, Tim Hahn, Alfons O Hamm, Ben J Harrison, Catharina A Hartman, Martin J Herrmann, Tiffany C Ho, Pieter J Hoekstra, Bharath Holla, Karim Ibrahim, Andrea Jackowski, Hamidreza Jamalabadi, Yali Jiang, Tilo Kircher, Kerstin Konrad, Anna Kraus, Jonna Kuntsi, Till Langhammer, Luisa Lazaro, Elisabeth J Leehr, Ulrike Lueken, Ren Ma, Frank P Macmaster, Gisele G Manfro, Anne Martinelli, Hannah Meinert, Susanne Meinert, Jarosław M Michałowski, Qingsen Ming, Robert Moeck, Lilianne R Mujica-Parodi, Benson Mwangi, Janina Neufeld, Joel T Nigg, Ruth L O'Gorman Tuura, Hyuntaek Oh, Jaap Oosterlaan, Yannis Paloyelis, Pedro M Pan, Luca Passamonti, Wenceslao Peñate, K Luan Phan, Kerstin J Plessen, Jesus Pujol, Karl Lundin Remnélius, Francisco Rivero, Katya Rubia, Ramiro Salas, Giovanni A Salum, Theodore D Satterthwaite, Anne Schienle, Elisabeth Schrammen, Koen R J Schruers, Gunter Schumann, Arjun Sethi, Tim Silk, Norbert Skokauskas, Jordan Smoller, Jair C Soares, Lin Sørensen, Christina Stadler, Michael C Stevens, Benjamin Straube, Thomas Straube, Andreas Ströhle, Gustavo Sudre, Denis G Sukhodolsky, Kate Sully, Xiaoqiang Sun, Chad M Sylvester, Nicola Toschi, Steven J A Van Der Werff, Alasdair Vance, Robert Vermeiren, Albert Wabnegger, Xiaoping Wang, Julia Wendt, Sarah Whittle, Julian Wiemer, Anderson M Winkler, Hans U Wittchen, Mon-Ju Wu, Qiong Wu, Tony T Yang, Yunbo Yang, Shuqiao Yao, Jibiao Zhang, Jiansong Zhou, Andre Zugman, Giovana B Zunta-Soares, Peter M Zwanzger, Sophia I Thomopoulos, Neda Jahanshad, Paul M Thompson, Kevin Hilbert, Arielle Baskin-Sommers, Charlotte A M Cecil, Moji Aghajani, Daniel S Pine, Nic J A Van Der Wee, Dan J Stein, Nynke A Groenewold, Janna Marie Bas-Hoogendam, Laura K M Han, Elena Pozzi, Lianne Schmaal, Barbara Franke, Martine Hoogman, Esther Walton, Stephane A De Brito, Graeme Fairchild, Enigma Antisocial Behavior, Anxiety, Adhd, And Mdd Working Groups Aug 2025

Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Mdd, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Mark A Bellgrove, Vivek Benegal, Robert J Blair, Laura Blanco-Hinojo, Ole Jonas Boeken, Joscha Böhnlein, Sven Bölte, Linda M Bonnekoh, Daniel Brandeis, Rodrigo A Bressan, Fabian Breuer, Willem B Bruin, Jan K Buitelaar, Katie L Burkhouse, Monica E Calkins, Marta Cano, Narcis Cardoner, Hui Chen, Xianliang Chen, David R Coghill, Olivier F Colins, Colm G Connolly, Michael C Craig, Kathryn R Cullen, Udo Dannlowski, Christopher G Davey, Andrea Dietrich, Daifeng Dong, Christine M Freitag, Thomas Frodl, Liesbet Goossens, Dominik Grotegerd, Raquel E Gur, Ruben C Gur, Jan Haavik, Cindy C Hagan, Tim Hahn, Alfons O Hamm, Ben J Harrison, Catharina A Hartman, Martin J Herrmann, Tiffany C Ho, Pieter J Hoekstra, Bharath Holla, Karim Ibrahim, Andrea Jackowski, Hamidreza Jamalabadi, Yali Jiang, Tilo Kircher, Kerstin Konrad, Anna Kraus, Jonna Kuntsi, Till Langhammer, Luisa Lazaro, Elisabeth J Leehr, Ulrike Lueken, Ren Ma, Frank P Macmaster, Gisele G Manfro, Anne Martinelli, Hannah Meinert, Susanne Meinert, Jarosław M Michałowski, Qingsen Ming, Robert Moeck, Lilianne R Mujica-Parodi, Benson Mwangi, Janina Neufeld, Joel T Nigg, Ruth L O'Gorman Tuura, Hyuntaek Oh, Jaap Oosterlaan, Yannis Paloyelis, Pedro M Pan, Luca Passamonti, Wenceslao Peñate, K Luan Phan, Kerstin J Plessen, Jesus Pujol, Karl Lundin Remnélius, Francisco Rivero, Katya Rubia, Ramiro Salas, Giovanni A Salum, Theodore D Satterthwaite, Anne Schienle, Elisabeth Schrammen, Koen R J Schruers, Gunter Schumann, Arjun Sethi, Tim Silk, Norbert Skokauskas, Jordan Smoller, Jair C Soares, Lin Sørensen, Christina Stadler, Michael C Stevens, Benjamin Straube, Thomas Straube, Andreas Ströhle, Gustavo Sudre, Denis G Sukhodolsky, Kate Sully, Xiaoqiang Sun, Chad M Sylvester, Nicola Toschi, Steven J A Van Der Werff, Alasdair Vance, Robert Vermeiren, Albert Wabnegger, Xiaoping Wang, Julia Wendt, Sarah Whittle, Julian Wiemer, Anderson M Winkler, Hans U Wittchen, Mon-Ju Wu, Qiong Wu, Tony T Yang, Yunbo Yang, Shuqiao Yao, Jibiao Zhang, Jiansong Zhou, Andre Zugman, Giovana B Zunta-Soares, Peter M Zwanzger, Sophia I Thomopoulos, Neda Jahanshad, Paul M Thompson, Kevin Hilbert, Arielle Baskin-Sommers, Charlotte A M Cecil, Moji Aghajani, Daniel S Pine, Nic J A Van Der Wee, Dan J Stein, Nynke A Groenewold, Janna Marie Bas-Hoogendam, Laura K M Han, Elena Pozzi, Lianne Schmaal, Barbara Franke, Martine Hoogman, Esther Walton, Stephane A De Brito, Graeme Fairchild, Enigma Antisocial Behavior, Anxiety, Adhd, And Mdd Working Groups

Staff and Researcher Publications

BACKGROUND: Externalizing and internalizing disorders are common in youth but are often studied separately, preventing researchers from identifying shared (i.e., transdiagnostic) alterations in brain structure. Using data from the ENIGMA Consortium, we conducted a mega-analysis to identify shared and distinct cortical and subcortical brain alterations across internalizing (anxiety disorders and depression) and externalizing disorders (attention-deficit/hyperactivity disorder [ADHD] and conduct disorder [CD]) in youth.

METHODS: 3D T1-weighted MRI data from youth (aged 4-21 years) with anxiety disorders (n=1,044), depression (n=504), ADHD (n=1,317), and CD (n=1,172), along with healthy controls (n=4,743) were analyzed. We assessed group differences in regional cortical thickness, surface …


Non-Isolated Tetralogy Of Fallot (Tof+): Exome Sequencing Efficacy And Phenotypic Expansions, Julia Volpi, Xiaonan Zhao, Nichole Owen, Tia Evans, Muriel Holder-Espinasse, Nayana Lahiri, Eleanor Sherlock, Gemma Poke, Jeroen Breckpot, Koen Devriendt, Bjorn Cools, Alfredo Brusco, Giovanni Battista Ferrero, Enrico Grosso, Pradeep Vasudevan, Sara Loddo, Antonio Novelli, Maria Cristina Digilio, Aafke Engwerda, Marrit Hitzert, Alison Male, Lucy Bownass, Ruth Newbury-Ecob, Zosia Miedzybrodzka, Ruth Armstrong, Sally Ann Lynch, Gunnar Houge, Shiyi Xiong, Seema R Lalani, Jill A Rosenfeld, Pamela N Luna, Chad A Shaw, Daryl A Scott Aug 2025

Non-Isolated Tetralogy Of Fallot (Tof+): Exome Sequencing Efficacy And Phenotypic Expansions, Julia Volpi, Xiaonan Zhao, Nichole Owen, Tia Evans, Muriel Holder-Espinasse, Nayana Lahiri, Eleanor Sherlock, Gemma Poke, Jeroen Breckpot, Koen Devriendt, Bjorn Cools, Alfredo Brusco, Giovanni Battista Ferrero, Enrico Grosso, Pradeep Vasudevan, Sara Loddo, Antonio Novelli, Maria Cristina Digilio, Aafke Engwerda, Marrit Hitzert, Alison Male, Lucy Bownass, Ruth Newbury-Ecob, Zosia Miedzybrodzka, Ruth Armstrong, Sally Ann Lynch, Gunnar Houge, Shiyi Xiong, Seema R Lalani, Jill A Rosenfeld, Pamela N Luna, Chad A Shaw, Daryl A Scott

Faculty, Staff and Students Publications

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect (CHD). TOF may present in isolation or in conjunction with one or more non-cardiac congenital anomalies or neurodevelopmental disorders (TOF+). Uncertainty regarding the efficacy of various genetic testing strategies, and an incomplete understanding of the genetic causes of TOF+, may lead to hesitancy in recommending genetic testing, particularly, clinical exome sequencing (cES). Here, we analyzed cES data from 131 individuals with TOF+. A definitive or probable diagnosis was made for 31 individuals, yielding a diagnostic rate of 23.6% (31/131). One individual received three diagnoses. Commercially available CHD panels …


Structural Basis For Membrane Microdomain Formation By A Human Stomatin Complex, Jack Stoner, Shufang Li, Ziao Fu Aug 2025

Structural Basis For Membrane Microdomain Formation By A Human Stomatin Complex, Jack Stoner, Shufang Li, Ziao Fu

2020-Current year OA Pubs

Biological membranes are not just passive barriers-they actively sense and respond to mechanical forces, in part through specialized proteins embedded within them. Among these are Stomatin-family proteins, which are known to influence membrane stiffness and regulate ion channels, yet how they achieve these functions at the molecular level has remained elusive. Here, we report the 2.2 Å cryo-electron microscopy structure of the human Stomatin complex in a native membrane environment. We find that Stomatin assembles into a 16-subunit ring-shaped homo-oligomer, forming a ~12 nm-wide cage that defines a mechanically distinct, curvature-resistant membrane microdomain. While the majority of the complex exhibits …


Longevity Os: Open Compendium Of Aging Biomarkers And Open-Source Intervention Protocols, Xavier Pillet Aug 2025

Longevity Os: Open Compendium Of Aging Biomarkers And Open-Source Intervention Protocols, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of ChatGPT o3 and ChatGPT 5 Thinking, is released under the Apache 2.0 licence. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (中华人民共和国专利法), and Japanese Patent Act Art. 29(1) (特許法). We disclose 77 enabling embodiments spanning assays/kits (telomeres, DNAm clocks, glycan-age, proteome, microbiome, metabolome, cfDNA-CHIP, mtDNA, 8-oxo-Gsn, NAD⁺), devices/sensors (AGE autofluorescence, VOP/PPG, continuous/interstitial NAD), …


Population Structure And Stock Assessment Of Tilapia Species In Coastal Lagoon, Lake Manzala, Egypt, Mohamed Fetouh, Kariman Shalloof, Attia El-Aiatt, Alaa El-Far, Walid Aly Aug 2025

Population Structure And Stock Assessment Of Tilapia Species In Coastal Lagoon, Lake Manzala, Egypt, Mohamed Fetouh, Kariman Shalloof, Attia El-Aiatt, Alaa El-Far, Walid Aly

Blue Economy

This study aimed to estimate the biology and population structure of cichlid species in Lake Manzala, where tilapias are the main catch. Samples were collected from commercial fishing boats in the fishing areas between 2019 and 2021. The length frequency distributions were evaluated using FiSAT II software. The results showed that Oreochromis niloticus was the most dominant species, making up 50% of the tilapia catch. Four age groups were found in O. niloticus and Coptodon zillii, and three in Oreochomis aureus and Sarotherodon galilaeus. Age group II was the most dominant across all species. The von Bertalanffy equation constants (L∞ …


Hitching A Ride On History: Nasa’S Space Launch System Artemis Ii Cubesats, Russell Lane, David Beaman, Courtney Ryals, David Hitt Aug 2025

Hitching A Ride On History: Nasa’S Space Launch System Artemis Ii Cubesats, Russell Lane, David Beaman, Courtney Ryals, David Hitt

Small Satellite Conference

In early 2026, NASA will launch the Artemis II mission, the second flight of its Orion spacecraft and Space Launch System (SLS) rocket. Artemis II will be the first crewed flight of the systems and will see four astronauts venture around the Moon as a key step toward establishing a long-term human presence in deep space. The 10-day flight will demonstrate NASA's foundational human deep space exploration capabilities. Launching along with Orion on SLS will be four 12U CubeSats developed through partnerships with space agencies around the world that are signatories of the Artemis Accords. The CubeSats will deploy in …


The Age Of Analysis, Morton Gabriel White Aug 2025

The Age Of Analysis, Morton Gabriel White

Hannah Arendt Marginalia - All

[New York] New American Library [1955]

Call #: B790 .W3

Contains underlining and marginal lining

PDF Information: 47 pages – 3.7MB


Platonic Studies, Gregory Vlastos Aug 2025

Platonic Studies, Gregory Vlastos

Hannah Arendt Marginalia - All

[Princeton, N.J.] Princeton University Press [1973]

Call #: B395 .V58

Contains underlining and marginal lining

PDF Information: 20 pages – 1,766KB


The New Science Of Giambattista Vico, Giambattista Vico Aug 2025

The New Science Of Giambattista Vico, Giambattista Vico

Hannah Arendt Marginalia - All

New York: Anchor Books, 1961

Call #: B3317 .S34

Contains marginalia and endpaper notes.

PDF Information: 42 pages – 17.6mb


Biopolitics, Thomas Landon Thorson Aug 2025

Biopolitics, Thomas Landon Thorson

Hannah Arendt Marginalia - All

New York, Holt, Rinehart and Winston [1970]

Call #: JA71 .T53

contains marginal lining, marginalia, underlining, and endnotes

PDF Information: 47 pages – 23 MB


Tbearr - Tardigrade Bio-Exploration Reproduction Research Satellite, Natalie Brattain, Kylie Nager, Joshua T. Lozano, Matas Ubartas, Chloe Nissen Aug 2025

Tbearr - Tardigrade Bio-Exploration Reproduction Research Satellite, Natalie Brattain, Kylie Nager, Joshua T. Lozano, Matas Ubartas, Chloe Nissen

Small Satellite Conference

The mission aims to launch four separate cultures of tardigrades aboard a 3U CubeSat to Low Earth Orbit to study the effects of UV and cosmic radiation on their genetics and cell composition, which may, in turn, affect their reproduction cycle.

• tBEARR is a 3U CubeSat mission under development by the Embry-Riddle Orbital Research Association (ERORA), an undergraduate research club at Embry-Riddle Aeronautical University in Daytona Beach, FL.

• Critical life support systems will be developed to maintain tardigrade viability as orbital experiments are being conducted.

• Tardigrades, in their cryptobiotic state, will be exposed to space radiation and …


A Comparative Analysis Of The Accuracy Of Retrieval Augmented Generation Versus Large Language Models For Gout-Related Queries, Samikchhya Keshary Bhandari, Himal Kharel, Zeni Kharel, Prajjwol Bhatta, Mouna Reghis, Ali Mohamed, Eduardo Avalos Sugastti, Chengu Niu Aug 2025

A Comparative Analysis Of The Accuracy Of Retrieval Augmented Generation Versus Large Language Models For Gout-Related Queries, Samikchhya Keshary Bhandari, Himal Kharel, Zeni Kharel, Prajjwol Bhatta, Mouna Reghis, Ali Mohamed, Eduardo Avalos Sugastti, Chengu Niu

Advances in Clinical Medical Research and Healthcare Delivery

Importance: To better understand ways to improve the answers from large language models by feeding them disease specific guidelines which can potentially act as a clinical decision support tool in the future Objective: To demonstrate the effect of retrieval augmentation on answers related to gout in terms of accuracy, conciseness and unambiguity. Design: Observational. Setting: Virtual experimental setting. Participants: ChatGPT 3.5 and Retrieval augmented generation powered ChatGPT. Exposure: Nine questions derived from the 2020 American College of Rheumatology guidelines on gout. Main outcomes: A zero to two subjective scale to measure the accuracy, conciseness, …


Radiologic Findings Of A Mediastinal Mass With Pleural Fluid Cytologic Analysis: A Case Report Of Recurrent Mantle-Cell Lymphoma, Mark Cwajna, Zaain Ahmad, Evan Basha, Emily Maggioncalda, Shehbaz Ahmad, Joel Thompson Aug 2025

Radiologic Findings Of A Mediastinal Mass With Pleural Fluid Cytologic Analysis: A Case Report Of Recurrent Mantle-Cell Lymphoma, Mark Cwajna, Zaain Ahmad, Evan Basha, Emily Maggioncalda, Shehbaz Ahmad, Joel Thompson

Advances in Clinical Medical Research and Healthcare Delivery

This case report details a 69-year-old male who presented with a right-sided pleural effusion and a mediastinal mass that was ultimately identified as recurrent mantle-cell lymphoma, occurring over 20 years after his initial diagnosis. Imaging findings discussed include chest radiograph and chest, abdomen and pelvis computed tomography depicting the mass compressing on various neighboring structures.


Clinical And Demographic Predictors Of The Need For Pharmacotherapy In Neonatal Abstinence Syndrome, Shawana Bibi, Rachana Singh, Janis L. Breeze, Jason Nelson, Walter K. Kraft, Jonathan M. Davis Aug 2025

Clinical And Demographic Predictors Of The Need For Pharmacotherapy In Neonatal Abstinence Syndrome, Shawana Bibi, Rachana Singh, Janis L. Breeze, Jason Nelson, Walter K. Kraft, Jonathan M. Davis

Department of Pharmacology and Experimental Therapeutics Faculty Papers

OBJECTIVE: Development and validation of a clinical prediction model for receipt of pharmacotherapy for Neonatal Abstinence Syndrome (NAS).

STUDY DESIGN: Data from three cohorts included

RESULTS: Of 698 infants included, 430 received pharmacotherapy. The final model included seven predictors of receipt of pharmacotherapy: gestational age, exposure to maternal breast milk, type of maternal opioid medication, and exposure to heroin, cocaine, benzodiazepines, and/or antipsychotic medications. The model had an AUROC of 0.68 (95% CI: 0.64-0.72; optimism corrected 0.65).

CONCLUSION: Our prediction model was parsimonious and identified seven predictors associated with the need for PT. Larger cohort studies are needed to more …


Circadian Influences On Glycemic Control In 24-Hr Fasts Initiated At Different Mealtimes, Elizabeth Z. Gipson Aug 2025

Circadian Influences On Glycemic Control In 24-Hr Fasts Initiated At Different Mealtimes, Elizabeth Z. Gipson

Theses and Dissertations

This study investigated whether the timing of a 24-hour fast influences indicators of glycemic control throughout the duration of the fast or upon refeeding. Twenty-four adults who have overweight or obesity (13 female, 11 male) completed this randomized crossover study involving three 24-hour fasts initiated at either 8:00 am, 1:00 pm, or 6:00 pm followed by a 75 g oral glucose tolerance test (OGTT) which lasted 2 hours. Continuous glucose monitors (CGMs) were employed to track interstitial glucose throughout each fast and OGTT. Plasma samples for insulin, glucagon, glucagon-like peptide-1 (GLP-1), and glucose-dependent insulinotropic polypeptide (GIP) were collected at the …


Growth Of Cylindrical Micelles And Their Use To Prepare Porous Materials With Tailored Dimensions And Alignment, Mengxue Zhang, Xiaomeng Li, Chuanbing Tang, Morgan Stefik Aug 2025

Growth Of Cylindrical Micelles And Their Use To Prepare Porous Materials With Tailored Dimensions And Alignment, Mengxue Zhang, Xiaomeng Li, Chuanbing Tang, Morgan Stefik

Faculty Publications

Materials with cylindrical pores are optimal for electrochemical devices and filtration due to their straight paths with minimal tortuosity when aligned. Polymer templates have led to many individual cylindrical architectures however the independent tailoring of pore and wall dimensions has remained elusive. Here short cylindrical micelle templates (PEO-b-PS) with glassy cores enabled the fabrication of sample series with constant cylindrical pore diameter (∼63 nm) and tailored wall thickness (TiO2, ∼45–100 nm). This ShortCyl series (aspect ratio 4.25) had modest alignment that was attributed to the low free-energy cost for misalignment. Though the plasticized micelles (DCM present) …


Optimization Of Rabbit Urine Liquid Organic Fertilizer And Reduced Npk Fertilizer Doses For Improving Growth And Physiology Of Shallot (Allium Ascalonicum L.), Etik Wukir Tini, Rifqi Raditya Kurniawan Aug 2025

Optimization Of Rabbit Urine Liquid Organic Fertilizer And Reduced Npk Fertilizer Doses For Improving Growth And Physiology Of Shallot (Allium Ascalonicum L.), Etik Wukir Tini, Rifqi Raditya Kurniawan

Jurnal Kultivasi

Rabbit urine liquid organic fertilizer (LOF) can be used as an alternative fertilizer to reduce the use of inorganic fertilizers, especially for shallots, as a national food commodity. This study aims to determine the best concentration of rabbit urine LOF, the best dose of NPK fertilizer dose reduction, and a combination of rabbit urine LOF and NPK fertilizer dose reduction on the physiological characters of shallot plants. The observed variables consisted of net assimilation rate, crop growth rate, stomatal density, stomatal aperture, and chlorophyll content. The experimental results showed that a concentration of 200 mL L-1 of rabbit urine LOF …


The Effect Of Melatonin And 6-Benzylaminopurine Application On The Post-Harvest Quality Of Cut Roses (Rosa X Alba), Azizah Tiara Putri, Syariful Mubarok, Rahmat Budiarto Aug 2025

The Effect Of Melatonin And 6-Benzylaminopurine Application On The Post-Harvest Quality Of Cut Roses (Rosa X Alba), Azizah Tiara Putri, Syariful Mubarok, Rahmat Budiarto

Jurnal Kultivasi

Roses are known as a high-value commodity frequently used in various important events. However, they are susceptible to postharvest quality deterioration, which can affect their vase life and appearance. In this study, roses with a blooming stage of approximately 25–50% were immersed in melatonin and 6-benzylaminopurine (BAP) solutions at different concentrations. This research aims to analyze the effect of melatonin and BAP application on the freshness of cut roses. The parameters observed included flower vase life, flower wilting angle, increase in flower diameter, fresh weight, solution uptake, and chlorophyll content. The results showed that melatonin and BAP, applied individually or …


Chemically Mediated Communication In Mound-Building Termites, Sree Subha Ramaswamy Aug 2025

Chemically Mediated Communication In Mound-Building Termites, Sree Subha Ramaswamy

Theses and Dissertations

Nest-building in social insects requires layered communication to coordinate complex, functional structures for housing, protection, storage, and homeostasis. This is especially striking in mound-building termites, which construct and repair large mounds collectively despite lacking image-forming eyes. This thesis investigates how Odontotermes obesus achieves such coordination through chemical communication embedded in soil.

Using controlled two-choice assays with manipulated soils, I separated airborne volatile signals from contact non-volatile signals by baking to remove volatiles, a mesh assay that presented volatile cues without contact, and solvent extraction with reapplication of contact cues. I quantified responses in major-only, minor-only, and mixed groups at two …


Magnetospectroscopic Studies Of A Series Of Fe(Ii) Scorpionate Complexes: Assessing The Relationship Between Halide Identity And Zero-Field Splitting, Daniel J. Santa Lucia, Laxmi Devkota, Sergey Lindeman, Andrew Ozarowski, J. Krzystek, Mykhaylo Ozerov, Samuel M. Greer, Daniel C. Cummins, Klaus H. Theopold, Mihail Atanasov, Joshua Telser, Adam T. Fiedler Aug 2025

Magnetospectroscopic Studies Of A Series Of Fe(Ii) Scorpionate Complexes: Assessing The Relationship Between Halide Identity And Zero-Field Splitting, Daniel J. Santa Lucia, Laxmi Devkota, Sergey Lindeman, Andrew Ozarowski, J. Krzystek, Mykhaylo Ozerov, Samuel M. Greer, Daniel C. Cummins, Klaus H. Theopold, Mihail Atanasov, Joshua Telser, Adam T. Fiedler

Chemistry Faculty Research and Publications

Ferrous ions in four-coordinate environments are common in protein structures, synthetic catalysts, and molecular magnets. The 3d6 configuration of high-spin Fe(II) imparts an S = 2 ground state, whose analysis using conventional spectroscopic methods is often hindered by substantial zero-field splitting (ZFS). Herein, we provide detailed electronic-structure descriptions for [FeIIX(TptBu,Me)] (1-X; X = F, Cl, Br, I), where (TptBu,Me)− is hydrotris(3-tert-butyl-5-methyl-pyrazol-1-yl)borate. The three pyrazolyl N-donors of the “scorpionate” ligand facially coordinate to Fe(II), giving idealized C3v symmetry with the halide occupying the axial position. Although originally reported …