Digital Commons Network^™

E-Cigarette Use And Its Associated Factors Among Pregnant Individuals Who Currently Or Formerly Smoked Cigarettes From Romania, Rana Jaber Phd, Oana M. Blaga, Marina Dascal, Cristian Meghea

Faculty Articles, Papers, and Other Scholarship

Abstract

Background and objective: Electronic cigarettes use among pregnant individuals who currently or formerly smoked cigarettes was not previously examined in Romania. This study aimed at measuring the prevalence of ever using e-cigarette and its associated factors in a sample of pregnant individuals in Romania who currently or formerly smoked cigarettes. Design: Cross sectional study from formative and baseline phases of a randomized control trial. Methods: This study utilized data from a Randomized control trial (RCT) that was conducted between 2016 and 2019 in Romania. Data was collected via structured questionnaire at formative stage and was self-administered through the study …

The Ruling Relations Of Care: An Institutional Ethnography Of High-Risk Prenatal Care Experiences, Nicole L. Harris

USF Tampa Graduate Theses and Dissertations

Disrespect during pregnancy, labor, and delivery is common in the United States. The Centers for Disease Control and Prevention has estimated that approximately one in five women overall, and over 30% of Black women, report being ignored, dismissed, or verbally mistreated during their care. Public health efforts have primarily focused on individual-level interventions to improve patient-provider communication or reduce provider bias; however, these strategies have been critiqued for their limited scope and effectiveness in shifting outcomes. Instead, researchers and advocates have called for an examination of the structures that shape clinical encounters, including policies, protocols, workflows, and organizational culture. This …

Using Rattlesnake Venom To Model Complex Trait Evolution Across Ecological And Evolutionary Scales, Samuel R. Hirst

USF Tampa Graduate Theses and Dissertations

A central challenge in evolutionary biology is understanding how genetic variation leads to phenotypicdiversity, particularly for complex traits that strongly influence fitness. Traits form the substrate of natural selection, but it is genes, that are inherited across generations. To fully understand the evolutionary process, we must therefore connect the molecular basis of trait variation with the evolutionary outcomes of such traits.

For relatively simple traits, the genotype–phenotype relationship is well understood. Classic systems, such as coat color in beach mice or toxin resistance in garter snakes, have provided effective examples of how relatively few loci underlie conspicuous adaptive differences across …

Analyzing Flexible Fillers For Enhanced Protection In Post-Tensioned Bridges, Amanda Armudi

Electronic Theses and Dissertations

Florida’s extensive coastline, dense network of bridges, and highly aggressive environmental conditions make corrosion a critical concern for the durability of bridges infrastructure. To minimize corrosion in bridge structures that use unbonded post-tension tendons, the Florida Department of Transportation (FDOT) is using flexible fillers as an alternative material to cementitious grout. This study evaluated the performance of five flexible fillers under sodium chloride (NaCl) exposure using NaCl solutions at concentrations of 10mM, 100mM and 1M over an 8-month period. Visual inspections revealed that filler composition and pre-existing cracks and voids in the filler samples significantly influenced degradation behavior. The samples …

The Bg News October 29, 2025, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 29, 2025. Volume 105-Issue 09.

Short Term Hemodynamic Effects Of Atrial Fibrillation In A Closed-Loop Human Cardiac-Baroreflex System, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, Mayuresh V. Kothare

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Atrial fibrillation (AF) remains the leading cardiac cause of stroke and AF-related death rate in the United States has been increasing for over twenty years. While the effect of standalone AF on heart rate is well established, there is a lack of clarity on its impact on other critical hemodynamic metrics. This is ostensibly due to interaction with other common comorbidities, especially hypertension. In addition, AF has a complex relationship with the state of the baroreflex. Evidence indicates that baroreflex sensitivity (BRS), the ability of the intrinsic cardiac control system to initiate parasympathetic response, is suppressed during AF. Therefore, a …

Long-Term Liver-Targeted Aav8 Gene Therapy For Mucopolysaccharidosis Iva, Shaukat A. Khan, Eliana Benincore-Florez, Fnu Nidhi, Jose Victor Álvarez, Dione A. Holder, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease with an autosomal recessive trait caused by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme, which leads to the accumulation of chondroitin-6-sulfate and keratan sulfate, primarily in cartilage and its extracellular matrix, resulting in a direct impact on cartilage and bone development, as well as subsequent systemic skeletal dysplasia. ERT and HSCT are current treatment options, but they have a limited effect on bone lesions. In this article, we investigated liver-specific AAV8 vectors with a thyroxine-binding globulin promoter in the MPS IVA murine model to evaluate the long-term (24 weeks in males …

Multinucleate Cell Angiohistiocytoma, Connor A. Sheehan, Jayci G. Rhein, Jordan Hyde, Jason B. Lee, Sylvia Hsu

Department of Dermatology and Cutaneous Biology Faculty Papers

No abstract provided.

Nasal Microbionts Differentially Colonize And Elicit Cytokines In Human Nasal Epithelial Organoids, Andrea I Boyd, Leah A Kafer, Isabel F Escapa, Amal Kambal, Hira Tariq, Susan G Hilsenbeck, Hoa Nguyen-Phuc, Anubama Rajan, Joshua M Lensmire, Kathryn A Patras, Pedro A Piedra, Sarah E Blutt, Katherine P Lemon

Faculty, Staff and Students Publications

Nasal colonization by Staphylococcus aureus or Streptococcus pneumoniae is associated with an increased risk of infection by these pathobionts, whereas nasal colonization by Dolosigranulum species is associated with health. Human nasal epithelial organoids (HNOs) differentiated at air-liquid interface (ALI) physiologically recapitulate human nasal respiratory epithelium with a robust mucociliary blanket. Due to their natural stem-like properties, HNO lines are a long-term experimental resource that offers genetic diversity based on the different donors. To develop HNOs as a new model system for bacterial nasal colonization, we reproducibly monocolonized HNOs differentiated at ALI with S. aureus, S. pneumoniae, or Dolosigranulum …

Fastk Post-Transcriptional Regulators – A ‘Fast-Track’ In Mitochondrial Gene Expression, Justin Van Riper, Bridget J Corsaro, Monica C Pillon

Faculty, Staff and Students Publications

Fas-activated serine/threonine kinase (FASTK) proteins comprise one of the largest families of mitochondrial post-transcriptional regulators. Members are classified based on their conserved C-terminus, which shows homology with the PD-(D/E)XK superfamily of endoribonucleases. However, it is still uncertain which of these FASTK members are catalytic. The six human FASTK homologs rely on their RNA-binding activity to regulate distinct stages of mitochondrial gene expression, including early processing of nascent RNA, 3'-end messenger RNA (mRNA) maturation, ribosomal RNA (rRNA) modification, mRNA stability, and translation. Genetic and genomic studies have highlighted the crucial role of FASTK proteins in balancing the mitochondrial transcriptome and controlling …

Translational Framework Linking Perfluoroheptanoic Acid (Pfhpa) Exposure To Metabolic Dysfunction Associated Steatotic Liver Disease In Adolescents, Brittney O Baumert, Ana C Maretti-Mira, Douglas I Walker, Zhenjiang Li, Nikos Stratakis, Hongxu Wang, Yinqi Zhao, Fabian Christoph Fischer, Qiran Jia, Damaskini Valvi, Scott M Bartell, Jiawen Carmen Chen, Thomas Inge, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Stavra Xanthakos, David E Kleiner, Rohit Kohli, Sarah Rock, Sandrah P Eckel, Michele A La Merrill, Max M Aung, Matthew P Salomon, Rob Mcconnell, Jesse Goodrich, David V Conti, Lucy Golden-Mason, Lida Chatzi

Faculty, Staff and Students Publications

Background: The rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), particularly among pediatric populations, requires identification of modifiable risk factors to control disease progression. Per- and polyfluoroalkyl substances (PFAS) have emerged as potential contributors to liver damage; however, their role in MASLD remains underexplored. This study aimed to develop a translational framework integrating human and in vitro data to elucidate the effect of PFAS on MASLD development.

Methods: We measured PFAS plasma levels in the Teen-LABS cohort (n = 136), comprising adolescents with obesity (mean age = 16.8 years) undergoing bariatric surgery. Plasma samples were also analyzed using proteomic …

Prevalence And Clinical Impact Of Pseudohypercalcemia In Paraproteinemia: A Case And Cohort Study, Usman Sunusi, Li Chen, Nianyi Li, Jason K Y Lee, Irmeen Siddiqui, Erin Goodhue, Rongrong Huang, Jieli Li

Faculty, Staff and Students Publications

Background: Hypercalcemia is a common and serious complication of malignancy, often contributing to morbidity and mortality. In patients with paraproteinemia, elevated total calcium with normal ionized calcium, termed pseudohypercalcemia, can complicate diagnosis and lead to inappropriate treatment. While this phenomenon has been described in case reports, its prevalence and clinical impact in routine practice remain poorly defined.

Methods: We report a case of pseudohypercalcemia in a patient with IgG κ multiple myeloma and conducted a retrospective review of de-identified data to assess the prevalence and biochemical associations of pseudohypercalcemia in paraproteinemia. Available data included serum protein electrophoresis (SPEP), …

Chromatin Profiling Identifies Putative Dual Roles For H3k27me3 In Regulating Cell Type-Specific Genes And Transposable Elements In Choanoflagellates, James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, Alex De Mendoza, David S Booth

2020-Current year OA Pubs

Chromatin-based mechanisms contribute to the exquisite regulation of gene expression during animal development. But how those mechanisms evolved remains elusive. Here we investigate chromatin regulatory features in the closest relatives of animals, choanoflagellates. In a model choanoflagellate Salpingoeca rosetta, we compare chromatin accessibility and histone modifications to gene expression. Accessible genomic regions in S. rosetta primarily correspond to gene promoters, and we find no evidence of distal gene regulatory elements that resemble enhancers deployed to regulate developmental genes in animals. Remarkably, the histone modification H3K27me3 decorates genes with cell type-specific expression, revealing a functional similarity in S. rosetta and animals. …

Brca2 Deficiency And Replication Stress Drive Apobec3-Mediated Genomic Instability, Kathy Situ, Abby M Green, Et Al.

2020-Current year OA Pubs

BRCA2 plays a critical role in stabilizing stalled replication forks, yet critical gaps remain in understanding how BRCA2 deficiency triggers fork collapse and drives genomic instability. Here, we identify cytidine deaminase APOBEC3B as a key driver of this process. Using a unique uracil-in-DNA probe, we show that BRCA2 loss promotes APOBEC3B-mediated uracil accumulation in single-stranded DNA (U-ssDNA) at stalled forks. These lesions when processed by UNG2 and APE1, trigger fork collapse and release ssDNA fragments into the cytoplasm, activating NF-κB signaling. This in turn upregulates APOBEC3B expression, establishing a self-reinforcing loop that amplifies cytidine deamination at stalled forks and exacerbates …

Biofilm Formation Of A Strain Of Bovine Escherichia Coli And Analysis Of Its Influencing Factors, Xin Zhang, Yunjiao Chen, Weijuan Jia, Zhilin Liu, Zelin Jia, Jiayu Cui, Huisheng Xiong, Yuhang Zhang, Xueli Wang

The Thai Journal of Veterinary Medicine

This study investigated the biofilm (BF) formation of a bovine-derived Escherichia coli (E. coli) strain (designated DL1907) and analyzed the factors influencing its formation. The BF-forming capacity, optimal formation time and temperature, as well as the effects of different culture media, pH levels, NaCl concentrations, and glucose concentrations, were assessed using the crystal violet method. The results demonstrated that the strain had a strong BF-forming capacity, achieving the most intact BF structure after 36 h of culture at 37°C. Trypticase Soy Broth (TSB) medium promoted the strongest BF formation compared to Luria-Bertani (LB) and Müller-Hinton Broth (MH) media. …

Molecular Identification Of Cryptosporidium Spp. Isolated From Dairy Calves In The Northern Region Of Algeria, Dadda Anes, Abdellah Mohamed Cherif, Aoun Leila, Chatanun Eamudomkarn, Khelef Djamel, Keeseon S Eom, Dongmin Lee, Barakaeli Abdieli Ndosi, Mohammed Mebarek Bia

The Thai Journal of Veterinary Medicine

Cryptosporidium spp. is the most frequent agent in Algeria that causes neonatal diarrhea in calves, with high symptomatic diarrhea in pre-weaned dairy calves. The study aims to measure the prevalence, distribution, and genotype of Cryptosporidium-infected calves in one of Algeria's high milk production areas (North Central and Northeast). From 35 dairy cattle farms were selected 172 (77 with diarrheic and 95 without diarrheic symptoms) calves aged less than 60 days. Twenty-three farms (65.71%) were detected with cryptosporidiosis using a modified Ziehl-Neelsen stain, whereby 68 calves (39.53%) were obtained positive. The Copro-ELISA test gave an individual prevalence of (37.66%, 22.11%) …

Drivers Of Policy Support And Political Consumerism Behavior Among Water Recreationists, Mina Kim

Proceedings of the Recreation Experience Community Network Research Symposium

Individuals who engage in water-based recreation share a distinct bond with water quality due to their direct contact with aquatic environments during leisure activities. Increasing concerns about water quality have led to a rise in research exploring how environmental conditions and perceived risks shape environmental attitudes and conservation actions. However, it remains uncertain whether water recreationists extend their conservation efforts beyond those directly tied to their activities. To explore this issue, the present study investigates whether water-based recreationists in South Carolina support more stringent water management policies and engage in political consumerism behaviors, such as boycotting and buycotting. Data were …

From The Field To The Future: How Experiential Learning Supports Student Success, Joshua Carroll, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

Field Experiences are often considered extracurricular, and not always a part of traditional college programs. However, these experiences can provide unique opportunities for learning, increase student confidence, broaden student perspectives of their chosen profession, and connect students with their environments, professors, and classmates. Because these programs often require a deep commitment from faculty, administrators, and the students, it is sometimes difficult to justify the resources required to successfully implement these courses. This project sought to identify several of the impacts that a field course may have on students, and to summarize these findings into sharable data for potential college and …

Fall 2025 Full Issue, Undergraduate Research

PANDION: The Osprey Journal of Research and Ideas

No abstract provided.

Spiny Orb Weaver, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic hardened, spiny abdomen. Spiny orb weaver spiders enjoy warm, tropical, and subtropical environments and are primarily found in the Southeastern U.S., the Caribbean, and South America. They live in wooded areas, citrus groves, and shrubby gardens. I’ve encountered spiny orb weaver spiders in my food forest where they like to set up their orb-shaped webs and feast on flies, mosquitoes, and moths.

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic …

Darkling Beetle, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Darkling beetles (Tenebrio molitor) are holometabolic insects. Darkling beetle is the common name of the large family of beetles Tenebrionidae which has more than 20,000 species. The T. molitor species gets its name from the yellowish appearance of the larvae. During its lifespan, a darkling beetle experiences a complete metamorphosis in four distinct stages: Egg, larva, pupa, and adult. The eggs hatch within 4 to 19 days after the female oviposits. It takes about 3 – 4 months for an egg to develop into an adult, or the beetle stage.

During the adult stage, the beetles are initially whitish and …

Horseshoe Crabs, Jessie M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Horseshoe crabs (Limulus polyphemus) are fascinating animals known as “living fossils.” Older than dinosaurs, horseshoe crabs are arthropods, closely related to spiders and scorpions. Many shorebirds, including red knot, depend on the eggs of horseshoe crabs during migration. Horseshoe crabs are captured and bled alive for their blue blood. Rich in limulus amebocyte lysate (LAL), their blood is used for the Limulus Amebocyte Lysate (LAL) test, which is used worldwide to detect bacterial toxins in pharmaceuticals and medical devices.

Horseshoe crabs have an intricate anatomy, so I spent a lot of time researching it before I started drawing them. When …

Probiotic Intervention In Managing Chronic Stress, Bianca Opdenbosch

PANDION: The Osprey Journal of Research and Ideas

Chronic stress can induce gut dysbiosis which contributes to the dysregulation of the gut-brain axis and leads to anxiety and depressive-like symptoms. The gut-brain axis relies on nervous, immune, and endocrine interactions. Gut dysbiosis, an imbalance within the gut microbiome, disrupts gut-brain communication, impairing gut barrier integrity, inflammation regulation, and hormonal and neurotransmitter production. These gut changes contribute to mood disorders resulting from stress, and thus it is important to implement dietary interventions, like probiotics, to help mitigate these effects. Research highlights the potential of probiotics to act as an intervention to combat stress-induced gut dysbiosis and replenish beneficial bacteria …

Rewilding The Built Environment: Navigating Economic, Political, And Social Barriers To Urban Ecological Restoration, Carly E. Smith

PANDION: The Osprey Journal of Research and Ideas

Urban rewilding offers a nature-based approach to restoring ecological processes in cities while advancing climate resilience, biodiversity, and public well-being. Unlike conventional green infrastructure, rewilding allows ecosystems to develop with minimal intervention, emphasizing succession, complexity, and long-term adaptability. This paper examines the political, economic, and social factors that frame how rewilding is understood and implemented in urban planning. Governmental frameworks often prioritize order, predictability, and short-term results, making it difficult to accommodate the uncertainty and ecological complexity that rewilding requires. Economic models struggle to capture its long-term value, frequently overlooking ecosystem services or reconciling competing land uses. Social perceptions of …

Listening To Wrong Beliefs: Being A Virtuous Agent In Contexts Of Disparity, Madison K. Mendiola

PANDION: The Osprey Journal of Research and Ideas

Using the concept of intellectual humility (IH) described by Whitcomb et al. (2021) and their application of IH in contexts of disparity, I will be furthering the discussion of the importance of IH when engaging with the other side. Although there are intellectual harms associated with being too open-minded, and moral concerns about being a listener to harmful ideas, I argue that epistemic agents risk committing an intellectual error when they don’t try to understand the beliefs of the in-the-wrong party. Even in contexts of disparity, you should be able to understand the other party’s belief-forming methodologies, which is compatible …

Analysis Of Mct-1 Expression In Mouse Neural Retina In Response To Chronic Inflammation, Ian W. Ronson

PANDION: The Osprey Journal of Research and Ideas

Chronic inflammation is a current public health concern as it is linked to the etiology and symptoms of numerous diseases, for example diabetic retinopathy (DR). In the case of DR, inflammation leads to dysregulation of the blood retina barrier causing retinal hemorrhage and macular edema leading ultimately to irreversible vision loss. MCT-1 is critical for the survival of photoreceptor cells because MCT-1 forms protein complexes with Basigin, a cell-cell adhesion protein, that enables Müller glial cells to efficiently provide lactate as a high energy fuel source. Previous studies have shown chronic inflammation reduces Basigin expression in the retina and that …

A Note From The Executive Editor, Judith D. Ochrietor

PANDION: The Osprey Journal of Research and Ideas

No abstract provided.

Enzymes Of Calendula Officinalis L. As Affected By Foliar Application Of Nano-Nitrogen And Potassium Fertilizers, Under Water Stress Conditions, Aqeel Abdulabbas Alsudani, Qais Hussain Abbas Al-Semmak

Karbala International Journal of Modern Science

Water stress is a major environmental factor that limits the growth and productivity of Calendula officinalis L. To alleviate its negative effects, recent approaches have increasingly focused on nano-fertilizers that enhance plant antioxidant defenses. This study therefore aimed to evaluate the effect of foliar application of nano-nitrogen (0, 2, and 4 mL L⁻¹) and nano-potassium (0, 2, and 4 g L⁻¹) fertilizers under two irrigation regimes (100% and 50% of field capacity) on the activity of key antioxidant enzymes, including catalase (CAT), superoxide dismutase (SOD), and peroxidase (POD). The results revealed that irrigation at 50% field capacity significantly increased CAT, …

“A Place, A Spirit, A Ministry”: The Persistence Of Koinonia Farm In The Post-Jordan Years, Ryan Geockner

Communal Societies

No abstract provided.

Narrative, Type And Emotion: Middle-Level Approach In Noel Carroll's Philosophy Of Art, Youxiang Gong

Theoretical Studies in Literature and Art

Noel Carroll's multidisciplinary research on philosophy of film, aesthetics and philosophy of art combines philosophy of language, philosophy of mind, ethics, cognitive science and biology, revealing the new trend of analytical aesthetics and philosophy of art in the late twentieth century. Carroll adopts an eclectic strategy in his middle-level approach to the philosophy of art. His method of historical narrative incorporates historical and narrative dimensions, complementing the history-intention theory and the institutional theory of art. He examines the traditional concept of mass art from a neutral position, attempting to construct the philosophy of mass art. He also relies on the …