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2025

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Utilization Of Dual Catalysts For High-Yield Boron Nitride Nanotube Synthesis Via Chemical Vapor Deposition, Şaban Kalay Dec 2025

Utilization Of Dual Catalysts For High-Yield Boron Nitride Nanotube Synthesis Via Chemical Vapor Deposition, Şaban Kalay

Turkish Journal of Chemistry

The direct synthesis of boron nitride nanotubes (BNNTs) via chemical vapor deposition (CVD) in high-temperature furnaces remains highly challenging due to difficulties in optimizing key experimental parameters such as synthesis temperature and catalyst composition. These challenges often result in uncontrolled growth behavior, adversely affecting the quality and yield of the BNNTs. In this study, colemanite was effectively utilized as a boron source for the high-yield synthesis of directionally aligned BNNTs. The synthesis was carried out using a CVD method that used a dual-catalyst system comprising Fe2O3 and MgO in conjunction with a silicon carbide template under high-temperature conditions. The resulting …


Bioorganometallic Tagging Of N-Acetylhistamine With An Fe(Co)₃ Unit: Synthesis, X-Ray Structure, And Protonation Behavior, Salah Merniz, Louiza Himed, Rofia Djerri, Belkis Akachat Dec 2025

Bioorganometallic Tagging Of N-Acetylhistamine With An Fe(Co)₃ Unit: Synthesis, X-Ray Structure, And Protonation Behavior, Salah Merniz, Louiza Himed, Rofia Djerri, Belkis Akachat

Turkish Journal of Chemistry

This study highlights the potential of organometallic carbonyl complexes as selective markers for biomolecules, enabling sensitive infrared (IR) detection. The regio- and stereoselective coupling of N-acetylhistamine, a histidine analogue, with the precursor complex 1 [Fe(CO)₃(1,4-η⁵-N-pyridiniocyclohexa-1,3-diene)] BF₄ affords the labeled complex 3 [Fe(CO)₃(1,4-η⁵-N-acetylhistaminocyclohexa-1,3-diene)]. X-ray diffraction (XRD) confirms the exo stereochemistry and reveals a rigid, well-defined architecture. IR and 1H nuclear magnetic resonance spectroscopic studies combined with IR-monitored acid–base titration demonstrate the complex’s stability in aqueous media between pH 5 and 8, alongside a modest increase in basicity relative to the free ligand. These findings establish the Fe(CO)₃ moiety as a robust …


Incidental Cardiac Metastasis In Breast Carcinoma, Yaomin Chen, Haibo Wang, Zhiyan Fu, Ellen Elizabeth Connor Dec 2025

Incidental Cardiac Metastasis In Breast Carcinoma, Yaomin Chen, Haibo Wang, Zhiyan Fu, Ellen Elizabeth Connor

School of Medicine Faculty Publications

Background and Clinical Significance: Metastatic breast cancer is a major global health burden, with common metastatic sites including the bones, lungs, liver, and brain. Cardiac metastasis is rare and often clinically silent, leading to underdiagnosis. Recognizing cardiac involvement, even when asymptomatic, is important for understanding the full extent of disease and ensuring optimal patient care. Case Presentation: We report the case of a woman with advanced breast carcinoma who showed no clinical or imaging evidence of cardiac involvement throughout the course of her illness. Following her death from progressive metastatic disease, an autopsy revealed metastatic carcinoma infiltrating the myocardium and …


Solving Data Mining Challenges In Neutrosophic Environments Using Bio-Inspired Optimization Techniques, Samia Mandour, Abduallah Gamal, Mohamed Belal Dec 2025

Solving Data Mining Challenges In Neutrosophic Environments Using Bio-Inspired Optimization Techniques, Samia Mandour, Abduallah Gamal, Mohamed Belal

Neutrosophic Sets and Systems

No abstract provided.


New Bis-Piperazine Derivatives: Synthesis, Characterization (Ir, Nmr), Gamma-Ray Absorption, Antimicrobial Activity, Molecular Docking And Dynamics Study, Yasemi̇n Ünver, Arzu Coşkun, Fati̇h Çeli̇k, Hali̇l İbrahi̇m Güler, Kadri̇ye İnan Bektaş Dec 2025

New Bis-Piperazine Derivatives: Synthesis, Characterization (Ir, Nmr), Gamma-Ray Absorption, Antimicrobial Activity, Molecular Docking And Dynamics Study, Yasemi̇n Ünver, Arzu Coşkun, Fati̇h Çeli̇k, Hali̇l İbrahi̇m Güler, Kadri̇ye İnan Bektaş

Turkish Journal of Chemistry

A series of novel bis-piperazine derivatives (2a–2f) were synthesized and structurally characterized via Fourier transform-infrared and nuclear magnetic resonance spectroscopic techniques. Their gamma-ray shielding efficiencies were investigated through simulations on the Monte Carlo-based Geant4-GATE platform, and the results were benchmarked against data obtained from the XCOM and Phy-X software. A simulation model incorporating an NaI scintillation detector and a point gamma source was developed. Key shielding parameters, including mass attenuation coefficient, linear attenuation coefficient, half-value layer, and mean free path (MFP), were evaluated at gamma energies of 80, 120, 662, 1173, and 1332 keV. Additionally, the energy absorption buildup factor …


Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇ Dec 2025

Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇

Turkish Journal of Chemistry

Human serum albumin (HSA) is a ubiquitous, multifunctional protein responsible for the systemic distribution of both endogenous metabolites and exogenous pharmaceuticals. Its inherent properties, particularly its ability to seep into tissues and its multiple ligand-binding sites, have rendered HSA an attractive vehicle for nanoparticle-based drug delivery systems, particularly for cancer targeting. In this study, we present high-resolution crystallographic data revealing two distinct dimerization patterns of HSA (Protein Data Bank [PDB] ID: 9V61) obtained under high-concentration crystallization conditions, along with results from dipyridamole docking. Both dimer types demonstrate extensive interface areas and a significant number of electrostatic interactions. Comparative analysis with …


Synthesis, Characterization, Antimicrobial, Antioxidant, And Antiinflammatory Evaluation And Molecular Docking Studies Of N-((2-Hydroxy-3-(2-(Substitutedbenzylidene)Hydrazine-1-Carbonyl)Naphthalen-1-Yl)(3-Nitrophenyl/3,4-Dimethoxyphenyl)Methyl)Acetamide Derivatives, Shikha Kamboj, Alka Yadav, Samridhi Thakral, Rekha Tanwar, Sunil Kumar, Vikramjeet Singh Dec 2025

Synthesis, Characterization, Antimicrobial, Antioxidant, And Antiinflammatory Evaluation And Molecular Docking Studies Of N-((2-Hydroxy-3-(2-(Substitutedbenzylidene)Hydrazine-1-Carbonyl)Naphthalen-1-Yl)(3-Nitrophenyl/3,4-Dimethoxyphenyl)Methyl)Acetamide Derivatives, Shikha Kamboj, Alka Yadav, Samridhi Thakral, Rekha Tanwar, Sunil Kumar, Vikramjeet Singh

Turkish Journal of Chemistry

Hydrazone chemistry has become important and plays a key role in the development of organic compounds. Hydrazones can be useful pharmacophores for creating novel derivatives, owing to their broad range of activities. In this study, a series of N-((2-hydroxy-3-(2-(substitutedbenzylidene)hydrazine-1-carbonyl)naphthalen-1-yl)(3-nitro-phenyl/3,4-dimethoxyphenyl)methyl)acetamide derivatives were prepared, characterized by FTIR, 1H-NMR, 13C-NMR, and mass spectroscopy, and evaluated for their antimicrobial, antiinflammatory, and antioxidant activities along with in silico studies. The substituted derivatives were synthesized by the reaction of acetonitrile, chlorosulphonic acid, and substituted benzaldehyde with the hydrazones. The antimicrobial evaluation showed that compound 3i had more antimicrobial potential than the other tested molecules. Compound 3j …


Enhancing Analytical Performance Of Tyrosinase-Based Sensors With Nanoparticles For Detection Of Isoproterenol, Aysel Oktay, Sevi̇nç Kurbanoğlu, Gülsüm Gündoğdu, Cem Bülent Üstündağ, Frieder W. Scheller, Aysu Yarman Dec 2025

Enhancing Analytical Performance Of Tyrosinase-Based Sensors With Nanoparticles For Detection Of Isoproterenol, Aysel Oktay, Sevi̇nç Kurbanoğlu, Gülsüm Gündoğdu, Cem Bülent Üstündağ, Frieder W. Scheller, Aysu Yarman

Turkish Journal of Chemistry

In this work, electrochemical biosensors utilizing tyrosinase (Tyr) for the detection of the nonselective beta-adrenergic agonist isoproterenol (ISO) are presented. Three different configurations for immobilizing Tyr on a graphite electrode (GE) are compared: (1) GE modified with poly(diallyldimethylammonium chloride) (PDADMAC), PDADMAC/Tyr/GE; (2) PDADMAC combined with iridium nanoparticles (IrNPs) in a stepwise preparation, resulting in PDADMAC/IrNPs/Tyr/GE; and (3) a composite of PDADMAC and IrNPs mixed with Tyr at a 1:1 (v:v), forming PDADMAC/(IrNPs-Tyr)/GE. Surface morphology was characterized using scanning electron microscopy (SEM). Cyclic voltammetry (CV) and amperometry were applied to characterize the biosensor’s performance. Within the linear range of 5 μM …


New Geographic Distributional Records For Fishes From The Black River At Black Rock, Lawrence County, Arkansas, C. T. Mcallister, H. W. Robison Dec 2025

New Geographic Distributional Records For Fishes From The Black River At Black Rock, Lawrence County, Arkansas, C. T. Mcallister, H. W. Robison

Journal of the Arkansas Academy of Science

During February and/or March 2020-2025, various fishes were collected with a modified minnow trap and hoop nets from the White River drainage of the Black River at Black Rock, Lawrence County, Arkansas. A total of 35 species within 11 families were collected and the following taxa represent new distributional records: Acipenseridae: Lake Sturgeon (Acipenser fulvescens); Polydontidae: Paddlefish, Polyodon spathula; Catostomidae: Quillback (Carpiodes cyprinus), Highfin Carpsucker (Carpiodes velifer), Blue Sucker (Cycleptus elongatus), Northern Hogsucker (Hypentelium nigricans); Leuciscidae: Creek Chub (Semotilus atromaculatus). The most significant discoveries were the collection …


Neutrosophic Super-Hypergraph Fusion For Proactive Cyberattack Countermeasures: A Soft Computing Framework, Ehab Roshdy, Marwa Khashaba, Mariam Emad Ahmed Ali Dec 2025

Neutrosophic Super-Hypergraph Fusion For Proactive Cyberattack Countermeasures: A Soft Computing Framework, Ehab Roshdy, Marwa Khashaba, Mariam Emad Ahmed Ali

Neutrosophic Sets and Systems

No abstract provided.


Mechanisms Behind Soil Water Evaporation And Infiltration During Long-Term Microbial Reclamation In Coal Mining-Induced Subsidence Areas In Northern Shaanxi Province, China, Ke Zengming, Bi Yinli, Yang Wei Dec 2025

Mechanisms Behind Soil Water Evaporation And Infiltration During Long-Term Microbial Reclamation In Coal Mining-Induced Subsidence Areas In Northern Shaanxi Province, China, Ke Zengming, Bi Yinli, Yang Wei

Coal Geology & Exploration

Background Water scarcity is identified as an important factor restricting ecological restoration in arid and semi-arid mining areas. The application of microbial reclamation technologies, especially inoculation with Arbuscular mycorrhizal fungi (AMF), has achieved encouraging ecological effects in mining areas. In this case, investigating soil water movement and its controlling factors in mining areas undergoing long-term microbial reclamation is a key scientific issue for understanding the long-term ecological restoration mechanisms of AMF. Methods This study investigated the microbial reclamation base in the coal mining-induced subsidence area of the Daliuta coal mine of northern Shaanxi Province, located in the middle reaches of …


An Experimental Study On The Selection Of Slow-Release Carbon Source Materials For Sulfate-Reducing Bacteria-Based Remediation Of High-Sulfate Mine Water In Coal Mines, Xiahou Ming’An, Zhang Li, Xu Zhimin, Guo Juan, Chen Ge, Xiong Xiaofeng, Sun Yajun Dec 2025

An Experimental Study On The Selection Of Slow-Release Carbon Source Materials For Sulfate-Reducing Bacteria-Based Remediation Of High-Sulfate Mine Water In Coal Mines, Xiahou Ming’An, Zhang Li, Xu Zhimin, Guo Juan, Chen Ge, Xiong Xiaofeng, Sun Yajun

Coal Geology & Exploration

Background High-sulfate mine water poses a major aquatic environmental challenge in coal mining areas across China. Accordingly, the cost-effective and efficient treatment of such water has become an urgent need for the sustainable development of the mining industry. Despite its considerable promise, microbial remediation based on sulfate-reducing bacteria (SRB) shows limited efficiency due to the scarcity of dissolved organic carbon (DOC) in mine water.Methods The application of external slow-release carbon source (SRC) materials for SRB faces a range of challenges, such as the potentially excessive release of organic carbon in the initial stage, the unclear release mechanisms of dissolved …


Water Quality Characteristics And Reutilization Of Goaf Water From Shallow Coal Seams Within The Datong Mining Area, Shanxi Province, China, Li Jun, Gui Herong, Ding Pengfei, Chen Yongqing, Wan Heyong, Li Weiqi, Huang Dawei, Peng Weihua, Hu Yang, Guo Yan Dec 2025

Water Quality Characteristics And Reutilization Of Goaf Water From Shallow Coal Seams Within The Datong Mining Area, Shanxi Province, China, Li Jun, Gui Herong, Ding Pengfei, Chen Yongqing, Wan Heyong, Li Weiqi, Huang Dawei, Peng Weihua, Hu Yang, Guo Yan

Coal Geology & Exploration

Objective The Datong mining area in Shanxi Province of China faces serious threats from goaf water hazards, while the goaf water drainage is constrained by environmental protection policies. Therefore, the reutilization of goaf water serves as an effective approach to eliminating mine water hazards, protecting water environments, and mitigating water scarcity in the mining area. Methods This study investigated goaf water from shallow coal seams in the Datong mining area. Based on water quality assessment theories and a range of hydrogeochemical indices, including saturation index (SI), chloro-alkaline index (CAI), and sodium adsorption ratio (SAR), this study conducted a joint determination …


Systemic Sclerosis-Associated Interstitial Lung Disease: Improved Understanding And Advances In Management, Amit Syal, Chris T. Derk Dec 2025

Systemic Sclerosis-Associated Interstitial Lung Disease: Improved Understanding And Advances In Management, Amit Syal, Chris T. Derk

Student Papers, Posters & Projects

Interstitial lung disease (ILD), a common manifestation of systemic sclerosis (SSc), has the highest organ-specific morbidity and mortality, particularly in patients with diffuse cutaneous SSc (dcSSc). Recent advances in diagnostics-including artificial intelligence (AI)-enhanced high-resolution computed tomography (HRCT) and biomarkers such as Krebs van den Lungen (KL)-6-have enabled earlier detection and monitoring of disease progression. Therapeutically, the approval of antifibrotics like nintedanib (NINT) and immunomodulators such as tocilizumab (Toci) has significantly expanded treatment options. Updated international guidelines from the American College of Rheumatology (ACR), American College of Chest Physicians (CHEST), American Thoracic Society (ATS), and European league against Rheumatism (EULAR) now …


Impact Of Physical Activity On Sleep In Adults Recovering From Substance Use Disorders: A Protocol For An N-Of-1 Observational Study, Sascha Thal, Cele Richardson, Joanne Mcveigh, Craig Thompson, Phoebe Wan, Bingyan Pang, Hugh Riddell, Stephen Bright, James Clarke, Bronwyn Myers Dec 2025

Impact Of Physical Activity On Sleep In Adults Recovering From Substance Use Disorders: A Protocol For An N-Of-1 Observational Study, Sascha Thal, Cele Richardson, Joanne Mcveigh, Craig Thompson, Phoebe Wan, Bingyan Pang, Hugh Riddell, Stephen Bright, James Clarke, Bronwyn Myers

Research outputs 2022 to 2026

Introduction Sleep impairments are prevalent among individuals recovering from substance use disorders (SUDs) and are associated with poorer treatment outcomes and increased relapse risk. Physical activity (PA) is known to enhance sleep in general populations, but its day-to-day effects on sleep during SUD recovery remain underexplored, especially across different recovery stages. Methods and Analysis In this observational n-of-1 study, we aim to examine within-person associations between daily PA and sleep quality in three groups of individuals at varying stages of substance use recovery (early treatment, continuing care and long-term recovery). A substudy will validate the agreement between two wearable sleepmonitoring …


Braingenebot: A Gpt-Engineered, User-Driven Genetic Data Exploration With Polygenic Risk Scores Ranking In Alzheimer’S Disease, Guan Ou, Zhongming Zhao Dec 2025

Braingenebot: A Gpt-Engineered, User-Driven Genetic Data Exploration With Polygenic Risk Scores Ranking In Alzheimer’S Disease, Guan Ou, Zhongming Zhao

Faculty, Staff and Student Publications

Background

Polygenic risk scores (PGSs) aggregate the effects of multiple genetic variants to attribute to disease susceptibility, and have been applied to numerous complex diseases including Alzheimer's disease (AD). However, as omics and phenotypic data grow exponentially, reconciling findings across studies with differing ancestral backgrounds, study designs, and statistical methodologies remains a pressing issue. Efficiently extracting biologically relevant insights from this expanding body of data is equally challenging, especially for diseases driven by complex interactions among genetic, environmental, and lifestyle factors.

Method

To address these challenges, we introduce BrainGeneBot, an AI‐driven chatbot framework that automates genetic data analysis and bridges …


On Performance Analysis Of A Neutrosophic Bipolar Fuzzy And Texture-Based Model For Covid-19 Detection From Chest X-Rays, Sanjayprabu S, Senthil Kumar L, Santhakumari R, Mareeswari R, Ajithkumar R Dec 2025

On Performance Analysis Of A Neutrosophic Bipolar Fuzzy And Texture-Based Model For Covid-19 Detection From Chest X-Rays, Sanjayprabu S, Senthil Kumar L, Santhakumari R, Mareeswari R, Ajithkumar R

Neutrosophic Sets and Systems

No abstract provided.


Neutrosophic-Based Feature Set (Nbfs) For Brain Tumor Detection Using Glcm Features And Knn Classifier On Mri Images, S. Gowri, V. M. Vijayalakshmi Dec 2025

Neutrosophic-Based Feature Set (Nbfs) For Brain Tumor Detection Using Glcm Features And Knn Classifier On Mri Images, S. Gowri, V. M. Vijayalakshmi

Neutrosophic Sets and Systems

No abstract provided.


Neutrosophic‑Enhanced Cephalometric Analysis With Improved Diagnostic Accuracy For Egyptian Population, Nagham Ahmed Abdelmegeed, Amal F. Abdel-Gawad Dec 2025

Neutrosophic‑Enhanced Cephalometric Analysis With Improved Diagnostic Accuracy For Egyptian Population, Nagham Ahmed Abdelmegeed, Amal F. Abdel-Gawad

Neutrosophic Sets and Systems

No abstract provided.


An Intelligent Soft Computing-Oriented Strategy For Managing Global Sustainability Issues In Dynamic Environments, Walaa M. Sabry Dec 2025

An Intelligent Soft Computing-Oriented Strategy For Managing Global Sustainability Issues In Dynamic Environments, Walaa M. Sabry

Neutrosophic Sets and Systems

No abstract provided.


Neutrosophic State Learning For High-Stakes Systems Using A Dynamic Triplet Model Of Support Contradiction And Uncertainty, Alaa Hassan And, Reda Ahmed Dec 2025

Neutrosophic State Learning For High-Stakes Systems Using A Dynamic Triplet Model Of Support Contradiction And Uncertainty, Alaa Hassan And, Reda Ahmed

Neutrosophic Sets and Systems

No abstract provided.


Evaluasi Keselamatan Alat Permainan Edukatif (Ape) Dan Penataan Area Bermain Outdoor Di Dua Taman Kanak-Kanak, Auri Willyado, Novrikasari Novrikasari, Mona Lestari, Dina Waldani, Desheila Andarini Dec 2025

Evaluasi Keselamatan Alat Permainan Edukatif (Ape) Dan Penataan Area Bermain Outdoor Di Dua Taman Kanak-Kanak, Auri Willyado, Novrikasari Novrikasari, Mona Lestari, Dina Waldani, Desheila Andarini

National Journal of Occupational Health and Safety

Educational Play Equipment (APE) is one of the facilities provided by Early Childhood Education (PAUD) institutions to support the learning process through play. This study aims to assess the compliance of APE and the arrangement of outdoor play areas with the 2018 Guidelines for Managing PAUD Classroom Space, SNI 9169:2023, the Ministry of Education and Culture’s 2021 Safe APE Guidelines for Early Childhood, and Ministerial Regulation No. 3 of 2022. The study employs a qualitative design with a descriptive approach through facility observations, interviews with teaching staff, and a review of school documents. The data analysis process includes data reduction, …


Real-World Outcomes Of Talimogene Laherparepvec As Salvage Therapy For Advanced Melanoma, Melissa M Yamada, Smitha Chandrasekhar, Ted A Gooley, Rita E Chen, Coley Doolittle-Amieva, George Ansstas, Shailender Bhatia, Evan T Hall, Paul T Nghiem, Song Y Park, David Y Chen Dec 2025

Real-World Outcomes Of Talimogene Laherparepvec As Salvage Therapy For Advanced Melanoma, Melissa M Yamada, Smitha Chandrasekhar, Ted A Gooley, Rita E Chen, Coley Doolittle-Amieva, George Ansstas, Shailender Bhatia, Evan T Hall, Paul T Nghiem, Song Y Park, David Y Chen

2020-Current year OA Pubs

BACKGROUND: Talimogene laherparepvec (T-VEC) is an oncolytic herpes simplex virus therapy approved for treatment of unresectable and metastatic melanoma. However, real-world use often occurs in heavily pretreated patients, where evidence of effectiveness remains limited. This study evaluates treatment responses and clinical factors influencing T-VEC outcomes in patients with diverse treatment histories.

METHODS: We analyzed patients with metastatic melanoma treated with T-VEC between 2015 and 2024. Objective responses (OR), complete response (CR) and partial response were assessed using univariate and multivariate Cox regression models. Durability of responses, progression-free survival (PFS), and overall survival (OS) were evaluated using Kaplan-Meier estimates.

RESULTS: Among …


Association Between Social Isolation And Risk Of Hypertension Among The Middle-Aged And Older: A Propensity Score–Matched Cohort Study, Yiting Kang, Minchao Liu Dec 2025

Association Between Social Isolation And Risk Of Hypertension Among The Middle-Aged And Older: A Propensity Score–Matched Cohort Study, Yiting Kang, Minchao Liu

Journal of Health Research

Background: Social isolation has emerged as a growing public health concern and may be an underrecognized risk factor for hypertension. However, evidence on its longitudinal association with hypertension remains limited and inconsistent.

Methods: The data of the national cohort study were collected from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020. A total of 3280 participants aged 45 years and older without hypertension at baseline were included. Propensity score matching (PSM) was applied to balance covariates between socially isolated and non-isolated groups. Cox proportional hazards models were used to estimate the association between social isolation and …


Attitude And Confidence In Managing Pre-Existing Type 2 Diabetes Mellitus During Pregnancy Among Thai Women, Ratchanok Phonyiam, Chiao-Hsin Teng, Catherine S. Sullivan, Aunchalee E.L. Palmquist, Eric A. Hodges, Yamnia I. Cortés, Marianne Baernholdt Dec 2025

Attitude And Confidence In Managing Pre-Existing Type 2 Diabetes Mellitus During Pregnancy Among Thai Women, Ratchanok Phonyiam, Chiao-Hsin Teng, Catherine S. Sullivan, Aunchalee E.L. Palmquist, Eric A. Hodges, Yamnia I. Cortés, Marianne Baernholdt

Journal of Health Research

Background: The trend of rising T2DM prevalence is more pronounced in females and is of particular concern for pregnancy. The rate has jumped from 0.7% to 1.5% of all pregnancies over the past 14 years. Additionally, pregnancies affected by T2DM have higher rates of abortion and perinatal mortality compared to those with type 1 diabetes mellitus and gestational diabetes mellitus. The objective of the study was to explore the attitudes and confidence in managing T2DM among Thai women during pregnancy.

Methods: This qualitative study was a part of a parent study using a convergent parallel mixed-methods design. A purposive sampling …


Enhancing Topical Delivery Of N-Acetylcysteine And Collagen Via A Novel Electrospun Collagen/Pmma Nanofibrous Mats As Facial Mask Development: Nanofibers Optimization And In Vitro Experiments, Samar A. Salim, Galala University, King Faisal University, Badr University, National Research Centre, City Of Scientific Research And Technological Applications (Srta-City),, Badr University Dec 2025

Enhancing Topical Delivery Of N-Acetylcysteine And Collagen Via A Novel Electrospun Collagen/Pmma Nanofibrous Mats As Facial Mask Development: Nanofibers Optimization And In Vitro Experiments, Samar A. Salim, Galala University, King Faisal University, Badr University, National Research Centre, City Of Scientific Research And Technological Applications (Srta-City),, Badr University

Nanotechnology Research Centre

This study endeavours to craft a potent topical facial mask using electrospun nanofibers. The nanofibers were carefully fabricated based on loading of N-acetylcysteine (NAC) onto electrospun marine collagen (MC), and poly (methyl methacrylate) (PMMA) nanofibers. Through precise adjustments of electrospinning parameters, a uniform array of nanoscale fibres with a smooth surface was achieved. The morphology and chemical structure configuration of nanofibers (NFs) were examined using SEM, FTIR, and XRD analyses. Furthermore, the cytotoxic impact was assessed on a human normal fibroblast cell line (BJ1), while protein levels were gauged using the Bradford dye-binding assay (Coomassie assay). Also, the antioxidant potential …


Absolute Extraction: Utilizing Rural Critical Criminology To Examine Appalachia’S Toxic Dependence On Extractive Industries, Andrew Kennedy Dec 2025

Absolute Extraction: Utilizing Rural Critical Criminology To Examine Appalachia’S Toxic Dependence On Extractive Industries, Andrew Kennedy

The Mid-Southern Journal of Criminal Justice

Brought forth by common rhetoric, Appalachia is often viewed as the closest space to that of an empyrean domain. Separated from the sleepless city, its allure rests in its created identity of a quiet, green escape from the city, which offers serenity on all fronts. Although Appalachia can fulfill this profile, such an ascension ignores the burning yellow grass below. The purpose of this paper is to examine the history of the destruction of Appalachia through the lens of extractive industries and the region’s designation as a sacrifice zone. Through the application of rural critical criminology, this paper holds that …


Bridging The Gap Between Substance Use Treatment Barriers In Rural Areas, Dakota Baker Dec 2025

Bridging The Gap Between Substance Use Treatment Barriers In Rural Areas, Dakota Baker

The Mid-Southern Journal of Criminal Justice

The purpose of this paper is to examine the continued concern about substance abuse/misuse and limited access to treatment in rural areas. Rural areas lack the adequate treatment needed to combat substance use disorder (SUD), mainly due to the lack of sufficient providers trained to identify, treat, and support those dealing with SUD. Additional barriers such as the high cost of treatment, stigma surrounding substance use disorders, geographical barriers, and the criminalization of substance abuse are other barriers that will be discussed in this paper (Griffin & Botvin, 2010; Hargons et al., 2023; Khazaee-Pool et al., 2024; National Center for …


Resting Autonomic Activity, Emotional Reactivity, And Executive Function In Preschool-Age Children Who Stutter, Dana J. Meyerson Dec 2025

Resting Autonomic Activity, Emotional Reactivity, And Executive Function In Preschool-Age Children Who Stutter, Dana J. Meyerson

Theses - ALL

Purpose: This study investigated whether preschool-aged children who stutter (CWS) differ from children who do not stutter (CWNS) in autonomic physiological reactivity and regulation during a phrase-repetition task paired with affective image-viewing conditions. Additionally, the study investigated whether individual differences in executive function skills, specifically inhibitory control, predicted variability in physiological responses across participants. Methods: Forty-three preschool-aged children (18 CWS, 25 CWNS) completed three laboratory visits that involved collection of electrocardiogram (ECG) recordings at rest and during a phrase-repetition task paired with visual stimuli of either neutral (fixation cross) or negative (IAPS) emotional valence. Inhibitory control was assessed using the …


Longitudinal Association Between Sleep Disturbance And Disordered Eating In Adolescents: The Mediating Role Of Emotion Dysregulation, Antonia Louise Hamilton Dec 2025

Longitudinal Association Between Sleep Disturbance And Disordered Eating In Adolescents: The Mediating Role Of Emotion Dysregulation, Antonia Louise Hamilton

Theses - ALL

Accruing evidence suggests a significant relationship between sleep disturbances and disordered eating. Early adolescence is a period of heightened vulnerability for sleep disturbances and disordered eating. However, the longitudinal relationship between sleep disturbance and disordered eating remains unclear in early adolescent samples. The current study aims to examine if sleep disturbance longitudinally predicts disordered eating in early adolescents three years later, how the odds of having clinically significant disordered eating change per each unit increase in sleep disturbance, and if emotion dysregulation mediates these relationships. It is hypothesized that baseline sleep disturbance will predict greater disordered eating at follow-up, and …