Digital Commons Network^™

Citronellol Reduces Sepsis-Induced Renal Inflammation Via Ap-1/Nf-Κb/Tnf-Α Pathway, Huda Rashid Atiyah, Sarmed H. Kathem, Surya M. Nauli

Pharmacy Faculty Articles and Research

Sepsis is characterized by the over-production of pro-inflammatory cytokines. Cecal ligation and puncture (CLP) is a well-accepted model for recreating sepsis-induced renal injury in mice. The current study investigates how citronellol, a naturally occurring substance with a variety of biological characteristics, can prevent acute kidney inflammation brought on by CLP. In the CLP mouse model, citronellol was administered orally at doses of 50 and 100 mg/kg. Serum levels of creatinine and urea were used as markers of renal function, and the Murine Sepsis Score (MSS) was used to assess the severity of sepsis. According to our findings, CLP caused a …

Development And Validation Of A Narrative-Based Personal Epistemology Scale: A Rasch-Guttman Scenario Approach, Luke Walden

Electronic Theses and Dissertations Archive

Quantitative measurement of personal epistemology has faced persistent challenges, with previous instruments often demonstrating poor psychometric functioning and instability across studies. This study introduces and provides an argument for the validity of the Epistemic Reasoning Measure (ERM), a novel scenario-based instrument utilizing the Rasch Guttman Scenario (RGS) methodology to assess absolutism and multiplism across a well-structured (biology) and an ill-structured (history) domain. A pilot sample of 350 undergraduate students and a second wave of 357 undergraduate students completed the four variants of the ERM (absolutism and multiplism for both biology and history). The psychometric properties of the scales were evaluated …

Introducing Neuro Sscial Work: A Brief Reflection On Neuroscience And The Profession, Priscila Llamosa

Social Work Faculty Publications

This reflection introduces and contextualizes the term Neuro Social Work, which I coin to name a specialized practice area at the intersection of social work, neuroscience, and neurodiversity. Drawing on my experience as a social work educator and practitioner, I discuss social work’s uneasy relationship with neuroscience, marked both by the opportunity to deepen our understanding of trauma, development, and healing, and by the risks of using brain‑based evidence to individualize structural harms or justify surveillance of marginalized communities. I outline, in broad strokes, what distinguishes Neuro Social Work from general neuroscience‑informed practice. The note is intended as a concept …

Use Of Calcium Modification In Percutaneous Coronary Intervention: A Comprehensive Review, Noyan Ramazani, Ala W. Abdallah, Michael V. Dicaro, Divyansh Sharma, Aditi Singh, Kachon Lei

Department of Internal Medicine Faculty Research

Calcified coronary lesions remain a challenge in percutaneous coronary intervention (PCI) in both situations of acute myocardial infarction (MI) and stable coronary syndrome. It significantly increases the risk of procedural complications due to difficulty in equipment delivery, balloon expansion, and stent delivery. Furthermore, stent thrombosis, dissection, perforation, and future in-stent restenosis occur more frequently in calcified coronary lesions, impacting repeat target vessel revascularization and increasing the risk of future MI. With intracoronary imaging (intravascular ultrasound and optical coherence tomography), peri-procedural success for treating calcified lesions has increased significantly. Different modalities of calcium modification techniques have since been introduced. This review …

Developing A Genetic Return Of Results Service Core, Jennifer A Mckenzie, Erin Mcroy, Kevin M Bowling, Jorge Luis Granadillo De Luque, Jessica Mozersky, Erin Linnenbringer, Dustin Baldridge, Jonathan W Heusel, Julie A Neidich, Amanda F Cashen, Laura J Bierut, Sarah M Hartz, Christina A Gurnett

2020-Current year OA Pubs

Research participants should be informed of genetic test results that could impact their health, particularly when they have expressed interest in receiving such information. Furthermore, the return of genetic test results is essential to improve trust, transparency, and health equity. However, investigators often encounter barriers in returning genetic test results to research participants. We examined genomic research at a large, research-intensive medical school and found less than 6% of protocols included plans to return results to participants. This study describes our development of protocols for returning primary and secondary genetic test results and implementation of a Genomic Return of Results …

The Daily Gamecock: November 2025, University Of South Carolina, Office Of Student Media

2025

No abstract provided.

Policy Project: Creating An Animal Assisted Therapy Policy For A College Of Nursing, Brooke Peyton

Doctor of Nursing Practice Projects

Nursing students experience high levels of academic stress, anxiety, and burnout, which can negatively impact learning, professional development, and overall health. Evidence indicates that Animal-Assisted Therapy (AAT) has the potential to impact stress levels, improve community connection, and enhance overall well-being among nursing students. Many academic institutions lack structured policies to guide AAT programs into educational settings. The purpose of this Doctor of Nursing Practice project was to develop a formal AAT policy for the College of Nursing with standardized procedures to implement an AAT program. Rogers’ Diffusion of Innovations theoretical framework was used to guide the development of the …

Quality Improvement Project Step Into Serenity: How Walking Can Ease Stress For Nursing Faculty, Stefanie Martinez

Doctor of Nursing Practice Projects

This quality improvement project explored whether incorporating scheduled walk breaks could help reduce perceived stress among accelerated Bachelor of Science in Nursing (ABSN) faculty. High levels of stress and burnout continue to affect nursing educators and contribute to faculty turnover and workforce shortages. The goal of this project was to promote physical activity as a simple and accessible approach to supporting well-being and fostering a healthier work environment. Grounded in George Engel’s Biopsychosocial Model of Health, this project introduced an educational session on faculty stress, burnout, and the benefits of walking. Participants completed the Perceived Stress Scale (PSS-10) before and …

Face Card Declined: The Deepfake Threat To Biometric Security In Financial Systems, Hazel Fernandez

Washington and Lee Law Review Online

Once limited to entertainment and disinformation, deepfakes are now extending into the financial sector, where voice and facial impersonations exploit biometric authentication systems to facilitate fraudulent transactions. This evolution exposes gaps in existing legal and regulatory frameworks, raising critical questions about consumer protection and institutional safeguards. This Note argues for a reconceptualization of deepfake harms as both a privacy and a financial security issue. It examines the illusion of consent generated by synthetic impersonation and insufficient statutory protections. The analysis examines the patchwork of federal, state, and international laws governing data privacy and artificial media, highlighting the gaps that allow …

Estrogen And Obesity Synergistically Suppress Protein S Via Hif1Α, Enhancing Thrombosis Potential, Mohammad A. Mohammad, Narender Kumar, Sonali Ghosh, Ashley L. Paysse, Claudia Leonardi, Vijaya Pilli, Ma Lorena Duhaylungsod, Eric Lazartigues, Diana Polania-Villanueva, Sadaf Nouman, Logan A. Barrios, Rima Chattopadhyay, Rafika Yasmin, Alaina Guilbeau, Manoj Kumar, Tina H. Nguyen, Jovanny Zabaleta, Li Li, Luis Del Valle M.D., Mallory T. Barbier, Samarpan Majumder, Laurent O. Mosnier, Samarpan Majumder

School of Graduate Studies Faculty Publications

Venous thromboembolism (VTE) is a leading cause of morbidity and mortality, with risk heightened in premenopausal women with obesity or use estrogen-based oral contraceptives. When both risk factors are present, the thrombosis risk increases substantially. Protein S (PS), an essential anticoagulant cofactor, is downregulated by both estrogen and obesity, but the molecular basis for this suppression remains poorly defined. We investigated the effect of estrogen and obesity on PS expression using plasma samples from 157 women stratified by BMI and contraceptive use, alongside 40 mice categorized as lean or obese with or without estrogen pellet treatment. The levels of PS …

The “I’M Too Much, Yet Never Enough” Paradox: A Critical Approach To Discourses Of Afro-Latinidad Among Second-Generation-Immigrant Women In South Florida, Eleni Victoria Webster

Electronic Theses and Dissertations

This study critically examines discourse and the ways it shapes identities and community belonging for self-identifying Afro-Latina, second-generation-immigrant women in South Florida. This qualitative research uses an intercultural communication framework to analyze interviews and collected poems. Informed by grounded theory and a Black feminist critical approach rooted in the intersectionality theory, the data is analyzed through comparative thematic and metaphorical rhetorical analyses. When discussing the discourses related to the development of ethno-racial identities for Afro-Latinas, certain communicative patterns of self-discovering, self-defining, and self-envisioning emerged. With regard to community belonging, three metaphorical discourses arose: not-enoughness, in-betweenness, and un-humanness. The internalization of …

The Edmonton Obesity Staging System For Pediatrics (Eoss-P) In Mexican Children And Adolescents Living With Obesity: Beyond Bmi Obesity Classes, Isabel Omaña-Guzmán, Roberto Carlos Rodríguez Quintero, Arturo Ruíz-Arroyo, Edith Prado Díaz, Juan Carlos Lopez Alvarenga, Ana María Hernández López, Zendy Fuentes Corona

School of Medicine Publications

Background/Objectives: The Edmonton Obesity Staging System (EOSS) was developed to stage the obesity in adult populations. Subsequently, this staging system was designed for pediatric populations (EOSS-P). This study aimed to describe obesity severity using EOSS-P and correlate it with BMI classes in Mexican children and adolescents living with obesity. Methods: This is a cross-sectional analysis carried out with data from school-age children and adolescents living with obesity who were referred to the Pediatric Obesity Clinic at the Child Welfare Unit at the General Hospital of Mexico “Dr. Eduardo Liceaga”. Obesity was staged using the EOSS-P. To evaluate the association between …

Does Preoperative Arthritis Affect The Outcomes Of Superior Capsular Reconstruction? A Systematic Review, Tae-Hoon Park, Hyungsuk Kim, Sukil Kim, Jongin Lee, Gerald R. Williams, Hyun Seok Song

Rothman Institute Papers

BACKGROUND: The optimal indications for superior capsular reconstruction (SCR) in cases of massive irreparable rotator cuff tears (RCTs) accompanied by degenerative arthritis remain controversial.

METHODS: A systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searching PubMed, Embase (Elsevier), and Google Scholar. Studies were included if they documented Hamada grade and reported clinical and radiographic outcomes after SCR for irreparable RCTs. American Shoulder and Elbow Surgeons (ASES) score, visual analog scale for pain (pVAS), active range of motion, and acromiohumeral distance (AHD) were analyzed.

RESULTS: In all 7 studies, there was no consistent …

Promising Effects Of Car T-Cell Therapy In Refractory Stiff Person Syndrome And A Hopeful Future For All Neuroautoimmunities, Marinos Dalakas

Department of Neurology Faculty Papers

Chimeric antigen receptor (CAR) T cells are genetically modified T cells expressing CARs, initially developed to recognize tumor antigens and kill cancer cells that evade T-cell recognition. Because of their impressive success in hemato-oncologic malignancies, CAR T cells are being repurposed with redesigned constructs for safety and sustained efficacy to target refractory systemic autoimmune or neurologic diseases. The CD19 CAR T cells-targeting those CD19-positive, antibody-secreting, long-lived plasma cells, and plasmablasts-are now extensively explored in refractory neuroautoimmunities with promising benefits based on case series in patients with myasthenia gravis (MG), stiff person syndrome (SPS), neuromyelitis, myositis, and multiple sclerosis; some patients …

Radiation Hardness Study Of Finfet And Gate-All-Around Fet Sram, Albert Lu

Master's Theses

Radiation, such as alpha particles or neutrons, is hard to control and can come from sources such as trace impurities or cosmic rays from space. These can then strike a semiconductor device, such as a Static Random Access Memory (SRAM) cell, and cause the SRAM to have its bit flipped. This bit flip is often just a temporary effect and is thus called a single event upset (SEU). Although it is temporary, a bit flip can cause severe consequences, such as affecting program functionality by causing incorrect data to be used. This is made worse in critical environments that need …

Secondary Teachers’ Instructional Strategies And Challenges In Teaching English Language Learners In Mississippi, Megan Cara Morgan

Walden Dissertations and Doctoral Studies

Mainstream high school teachers in a district in the state of Mississippi have struggled to consistently implement research-based strategies that address the needs of English Language Learners (ELLs). Guided by Echevarría et al.’s sheltered instruction observation protocol (SIOP), the purpose of this basic qualitative study was to explore the instructional practices implemented by mainstream high school teachers at a Title I high school in a Mississippi district that are aligned with research-based practices and the challenges they reported in improving ELL student achievement in mainstream classrooms. Data were collected from semistructured interviews with nine teachers from a Title I high …

Tlr2 Agonism Suppresses Myeloid Leukemogenesis By Reprogramming Leukemia Stem Cells, Michael E. Lawler, Jennifer S. Romer-Seibert, Michael S. Bowman, Ramkrishna Mitra, Christine M. Eischen, Robert L. Bowman, Sara E. Meyer

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

The consequences of activated innate immune signaling in acute myeloid leukemia (AML) is not well understood. Using ligands directed at the toll-like family receptors (TLR) in models of high-risk AML, we uncover that TLR2 ligands exert unique antileukemic effects that are distinct from other TLRs. Although TLR2 signaling broadly induces inflammatory gene expression in AML cells, at the single-cell level, cell-type-dependent, divergent transcriptional responses coordinate cellular outputs of proliferation, differentiation, cell death, and activation of immune cell function. TLR2 ligands were the only TLR agonists capable of extending survival of AML-bearing mice through leukemia stem cell (LSC) reprogramming that elevated …

Successful Multi-Author Publication: Responsive Respectful Teamwork And Lessons Learned, Dorette Sugg Welk

Biennial Convention (CONV)

When two or more professionals engage in a scholarship project to develop and publish a journal manuscript, numerous questions could be considered at the outset for best outcomes. An international 10-person effort of Sigma colleagues to publish a manuscript followed a general collaborative plan of ten rules for such an initiative (Frassl et al., 2018). The purpose of this presentation is to describe how these rules spawned questions and actions for a successful publication outcome. Lessons learned may also inform others. Being responsive and respectful in an international collaboration supports scholarly productivity.

Questions considered: What journals and impact factors meet …

Cordmilk: Umbilical Cord Milking Versus Early Cord Clamping On Short-And Long-Term Outcomes In Neonates Who Are Non-Vigorous At Birth-Study Protocol Of A Multi-Center, Cluster-Randomized, Crossover-Controlled Trial, S. Yogeshkumar, Sunil S. Vernekar, Sangappa M. Dhaded, Kiran Talekar, Benjamin E Leiby, Rebecca Hartman, Yvonne Vaucher, Nitin Chouthai, Meenakshi Girish, Manish Jain, Shuchi Jain, Seema Parvekar, Vinita Jain, Alka Patankar, Milind Suryawanshi, Manish Tiwari, Manjushri Waikar, Nidhi Nashine, Deepali Ambike, Mahesh Asalkar, Rajesh Kulkarni, Sandhya Haribhaktha, Hemraj Narkhede, Sudha Chaudhari, Milind Kamble, Deepti Shrirame, Balchandra Falke, Seema Mehta, Asha Verma, Sunil Gothwal, Shivaprasad S. Goudar, Richard Derman, Anup Katheria, Zubair H. Aghai

Department of Radiology Faculty Papers

BACKGROUND: Facilitating placental transfusion-the transfer of blood from the placenta to the newborn-via delayed cord clamping (DCC) or umbilical cord milking (UCM) at birth has been shown to improve iron stores in healthy term infants and may positively impact long-term neurodevelopmental outcomes. Infants who are non-vigorous at birth and at risk of developing hypoxic-ischemic encephalopathy (HIE) are particularly likely to benefit from placental transfusion. This process may offer neuroprotection by enhancing cardiopulmonary transition, supporting cardiac preload, improving systemic and cerebral perfusion, delivering stem cells and neurotrophic factors, and preventing iron deficiency. While DCC is not currently recommended for non-vigorous term …

Multiomic Analysis Reveals A Key Bcat1 Role In Mtor Activation By B Cell Receptor And Tlr9, Rui Guo, Yizhe Sun, Matthew Y Lim, Hardik Shah, Joao A Paulo, Rahaman A Ahmed, Weixing Li, Yuchen Zhang, Haopeng Yang, Liang Wei Wang, Daniel Strebinger, Nicholas A Smith, Meng Li, Merrin Man Long Leong, Michael Lutchenkov, Jin Hua Liang, Zhixuan Li, Yin Wang, Rishi Puri, Ari Melnick, Michael R Green, John M Asara, Adonia E Papathanassiu, Duane R Wesemann, Steven P Gygi, Vamsi K Mootha, Benjamin E Gewurz

Faculty, Staff and Student Publications

B lymphocytes play major adaptive immune roles, producing antibodies and driving T cell responses. However, how immunometabolism networks support B cell activation and differentiation in response to distinct receptor stimuli remains incompletely understood. To gain insights, we systematically investigated acute primary human B cell transcriptional, translational, and metabolomic responses to B cell receptor (BCR), TLR9, CD40-ligand (CD40L), IL-4, or combinations thereof. T cell-independent BCR/TLR9 costimulation, which drives malignant and autoimmune B cell states, highly induced transaminase branched chain amino acid transaminase 1 (BCAT1), which localized to lysosomal membranes to support branched chain amino acid synthesis and mTORC1 activation. BCAT1 inhibition …

Dual Language In Higher Education: Assessing Student Success And Student Experiences, Katherine Christoffersen, Ramsés Ortín, Dania López García, Ming-Tsan Lu, Javier Cavazos Vela

Writing and Language Studies Faculty Publications

Although long-standing research has documented the many benefits of dual language (DL) education programs in the K-12 setting, there are few studies on the impact of DL in higher education. This study analyzes DL education at a Hispanic-Serving Institution (HSI) where certain classes are taught in Spanish or bilingually across diverse disciplines. In this mixed methods research study, we examine (1) how enrollment in these classes impacts student success through an analysis of cumulative grade point averages, retention, and time to degree and (2) how students perceive these classes through an analysis of course evaluations and surveys responses from current …

Intercellular Signaling And Synaptic Deconstruction Uncovered By Single-Cell And Spatial Transcriptomics In An Ad Tauopathy Model, Jeff X. Ji, Brian L. Giles, Surjyadipta Bhattacharjee, Marie-Audrey I. Kautzmann, Alasdair P. Masson, Sonia Do Carmo, A Claudio Cuello, Nicolas G. Bazan

School of Medicine Faculty Publications

Alzheimer's disease (AD) is the leading cause of dementia in elderly individuals worldwide; however, all mechanisms leading to disease onset and progression are not well understood. Here, we report brain single-cell multiome and spatial transcriptomics in a transgenic rat model of human-like tauopathy. We have identified new markers of tau-driven AD pathology and provided single-cell evidence for genes implicated in AD. Our findings reveal how tau hyperphosphorylation and aging alter ligand-receptor communication, transcription factor regulatory networks, and specific cellular networks. Notably, we found intriguing changes in cell communication involving glutamatergic transmission and Netrin signaling as a taupathy consequence. Overall, this …

Chimes: November 17, 2025, Calvin University

Chimes

Budget cuts slash programs and faculty: Students react with grief and frustration by Sarah Sparling, Ian Tjoelker & McKenna Wilkinson

Bringing the Cretaceous to Calvin: Dice Museum reveals fossil and student artwork by Ellery Johnson

Recap: 200 students attend administration town hall by Sarah Sparling

Celebrating Calvin's Asian American and international populations by Jorie Cho

Calvin's D1 hockey on hot streak as they climb to #4 in national rankings by Hendrik Beelen & Zach Kern

Spotted turtles find their home on campus by Maya Oeverman

Student Senate allocates four thousand dollars to accessibility and sustainability projects by Ashley Hamons

Cultural Innovation Can Increase And Maintain Biodiversity: A Case Study From Medieval Europe, Adam Spitzig, Manfred Rösch, Jessie Woodbridge, Martin Bauch, Piotr Guzowski, Peter Erhart, Ralph Fyfe, Elena Marinova, Adam Izdebski

School of Geography, Earth and Environmental Sciences

Numerous research efforts have used paleoecological data to reconstruct past biodiversity in Europe. In these projects, researchers have identified increases in biodiversity over the Holocene and hinted at a positive correlation with human population. These are important findings but are not easily translated into effective biodiversity conservation and restoration policy. We argue that, in order to better inform policymaking, studies of past biodiversity dynamics should include analyses of contemporaneous cultural phenomena in order to identify and describe specific anthropogenic drivers of past biodiversity changes. We present an example here, a case study from the Lake Constance region (southwestern Germany), one …

Describing The Determinants Of Fluid Prescribing And Fluid Balance Optimization In The Pediatric Intensive Care Unit: A Qualitative Study At A Community Hospital, Salvador Roland Maffei, Graciela Sanabria, Matthew Pesek, Ayse Akcan-Arikan, Satid Thammasitboon, Patrick G Lyons

Faculty, Staff and Students Publications

Background: Critically ill children tend to receive fluid volumes exceeding physiologic requirements despite evidence demonstrating harm with increasing net positive fluid balance. However, interventions aimed at optimizing fluid balance have yet to demonstrate significant clinical benefit, likely because there are multiple drivers of this complex problem. In this study, we used qualitative inquiry to describe the current practice at a community pediatric intensive care unit and discover potential barriers and facilitators to clinical practice change.

Methods: We designed a semi-structured interview guide informed by the consolidated framework in implementation research (CFIR) and conducted interviews with attending physicians, dietitians, nurses, nurse …

Ptbp1 Variants Displaying Altered Nucleocytoplasmic Distribution Are Responsible For A Neurodevelopmental Disorder With Skeletal Dysplasia, Aymeric Masson, Catherine Gooch, Et Al.

2020-Current year OA Pubs

Polypyrimidine tract-binding protein 1 (PTBP1) is a heterogeneous nuclear ribonucleoprotein primarily known for its alternative splicing activity. It shuttles between the nucleus and cytoplasm via partially overlapping N-terminal nuclear localization (NLS) and export (NES) signals. Despite its fundamental role in cell growth and differentiation, its involvement in human disease remains poorly understood. We identified 27 individuals from 25 families harboring de novo or inherited pathogenic variants - predominantly start-loss (89%) and, to a lesser extent, missense (11%) - affecting NES/NLS motifs. Affected individuals presented with a syndromic neurodevelopmental disorder and variable skeletal dysplasia with disproportionate short stature with short limbs. …

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

درجة تضمين كتب اللغة الانكليزية السورية الصفين السابع والثامن لمؤشرات الذكاء اللغوي. The Degree Of Inclusion Of Linguistic Intelligence Indicators In The Seventh And Eighth Grade English Textbooks In Syria, سيناء مجمد ذيب الخطيب الجشي

Association of Arab Universities Journal for Education and Psychology

هدف البحث لمعرفة درجة تضمين كتب اللغة الإنكليزية الصفين السابع والثامن (كتاب الطالب وكتاب الأنشطة) في سورية لمؤشرات الذكاء اللغوي، ولتحقيق الهدف تم استخدام المنهج الوصفي التحليلي من خلال أسلوب تحليل المحتوى، وتم إعداد قائمة بمؤشرات الذكاء اللغوي تبعًا للمهارات اللغوية الخمس (الاستماع، القراءة، التحدث، الكتابة، الحس اللغوي)، وأجري لها اختبارات الصدق والثبات اللازمة لضمان موثوقية الأداة.

ولتحليل النتائج اُستخدمت التكرارات والنسب المئوية واختبار كا²(x²) لحسن المطابقة، وجاءت نتائج التحليل كالآتي: أن توزع الذكاء اللغوي جاء متوازن بالنسبة لكتاب الطالب في الصف السابع، بينما لم يكن متوازن بالنسبة للصف الثامن، وبالنسبة لكتابي الأنشطة لم يظهر التحليل …

Microplastic Variability In Wetland Sediments And Vegetation: A Case Study Of Spruce Bluff Preserve, Fl, Juana Maria Baudrix

Electronic Theses and Dissertations

Plastic pollution has become an imminent threat to the environment and human health. This study explores the occurrence, distribution, and retention mechanisms of microplastics (MPs) in Spruce Bluff Preserve, a 97-acre freshwater wetland ecosystem located along the eastern bank of the St. Lucie River in Port St. Lucie, FL. Understanding MP dynamics in transitional freshwater ecosystem is crucial for environmental management efforts given Florida’s heavily fragmented and managed landscape. This research specifically examined the relationship between wetland vegetation and MP retention in sediments across different ecological zones within the preserve. Surface sediment samples were collected along 8 transects of varying …

Cephalopod Consciousness On “Their Own Terms”: Who Are “They”?, Willa M. Lane, Victor Ajuwon, Nicola S. Clayton

Animal Sentience

Mather’s call to consider cephalopods’ consciousness “on their own terms” raises the question of the extent to which cephalopods can be considered a homogenous group. While coloeoid cephalopods share traits that strongly distinguish them from other molluscs and invertebrates, they show vast ecological and morphological diversity, with implications for the design of empirical investigations of consciousness. Extending Mather’s argument, we apply Birch et al.’s (2020) five-dimensional model to compare octopus, cuttlefish, squid, and nautilus. This comparison shows that even within a graded rather than categorical framework, putative consciousness profiles depend on which taxa are included in discussions of “cephalopod consciousness.” …