Digital Commons Network^™

Antibiotic Susceptibility Of Bacterial Contaminants In Tissue-Cultured Musa Acuminata ‘Lakatan’ And Musa Textilis ‘Inosa’, Brendell Philip B. Tejoso, Lourna Mae Q. David, Emmanuel L. Bernardo, Carlo Miguel C. Sandoval, Renard M. Jamora

Journal Article

Banana (Musa acuminata) and abaca (Musa textilis) are economically important crops in the Philippines. However, both crops are increasingly threatened by disease outbreaks, which can be mitigated through mass propagation using tissue culture techniques. Tissue culture propagation, however, is often compromised by bacterial contamination originating from either environmental or endophytic sources. In this study, bacterial isolates from environmental surfaces and tissue-cultured explants were characterized using morphological and biochemical profiling. Environmental isolates consisted of Gram-positive and Gram-negative short rods, whereas tissue culture contaminants were predominantly Gram-negative short rods and a single Gram- positive coccus. This morphological distinction suggests that the tissue …

Mobile Health Intervention Tools Promoting Hiv Pre-Exposure Prophylaxis Among Adolescent Girls And Young Women In Sub-Saharan Africa: Scoping Review, Alex Emilio Fischer, Homaira Hanif, Jacob B. Stocks, Aimee E. Rochelle, Karen Dominguez, Eliana Gabriela Armora Langoni, H. Luz Mcnaughton Reyes, Gustavo F. Doncel, Kathryn E. Muessig

Department of Obstetrics & Gynecology Faculty Publications

Background:

In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited uptake and persistence. Mobile health (mHealth) interventions can improve medication adherence; however, their utility to improve PrEP adherence among adolescent girls and young women is not well established.

Objective:

This scoping review synthesizes evidence supporting mHealth for PrEP among adolescent girls and young women in sub-Saharan Africa and identifies strategies for further evaluation.

Methods:

We searched PubMed and Google Scholar databases, expert referrals, and reference lists using the following eligibility …

Longitudinal Assessment Of Intravillous Arterioles In Normal Pregnancy Using Superb Microvascular Imaging, R. Horgan, E. Sinkovskaya, G. Saade, E. Kalafat, A. Heeze, A. Abuhamad

Department of Obstetrics & Gynecology Faculty Publications

Objective

To use superb microvascular imaging (SMI) to longitudinally evaluate blood flow in intravillous arterioles (IVA) in pregnancy, and to develop reference ranges for IVA pulsatility index (PI) and peak systolic velocity (PSV) from 12 to 38 weeks' gestation.

Methods

The data for this study were obtained from the National Institutes of Health-funded Human Placenta Project. Eligible for inclusion were women aged 18-35 years, with a body mass index of <  30 kg/m², without comorbidities, with a singleton pregnancy conceived spontaneously and a gestational age of ≤ 13 + 6 weeks. Exclusion criteria were maternal or neonatal complications, fetal or umbilical cord anomalies, abnormal placental implantation and delivery <  37 weeks. Each participant underwent eight ultrasound examinations during pregnancy. Using SMI technology, the total number of IVA identified was recorded in a sagittal placental section at the level of cord insertion. The PI and PSV were measured in a total of six IVA (two in the central portion of the placenta, two peripherally towards the uterine fundal portion and two peripherally towards the lower uterine segment). Umbilical artery (UA)-PI was also obtained. Multilevel regression models were used to create reference ranges for IVA-PI and IVA-PSV at 12-38 weeks' gestation.

Results

A total of 90 women fulfilled the study criteria. IVA-PI decreased throughout pregnancy from a mean ± SD of 1.04 ± 0.23 in the first trimester (at 12-13 weeks) …

American Heart Association Blood Pressure Classification And Subsequent Risk Of Preeclampsia, Rebecca Horgan, Erkan Kalafat, Elena Sinkovskaya, Alfred Abuhamad, George Saade

Department of Obstetrics & Gynecology Faculty Publications

Background: In 2017, the American Heart Association (AHA) and American College of Cardiology updated their hypertension guidelines for the nonpregnant population, lowering the diagnostic thresholds to systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg. This reclassification has raised important questions regarding whether blood pressure (BP) values previously considered within the normal range in pregnancy may, in fact, confer an increased risk for hypertensive disorders of pregnancy (HDPs).

Objective: To evaluate the association between first-trimester BP classified by AHA thresholds and the subsequent development of HDPs.

Study design: This was a secondary analysis of a prospective, multicenter cohort …

Investigation Of Rna-Binding Protein Expression Changes In The Hippocampus Following Doxorubicin And Cyclophosphamide Treatment, Lijie Chen

Dissertations and Theses

This study investigated the molecular mechanisms underlying chemotherapy-induced cognitive impairment (CICI) following doxorubicin and cyclophosphamide treatment in a rat model, revealing three significant alterations in hippocampal tissue: selective downregulation of heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) (21% decrease, p=0.0298), compromised astrocytic network integrity evidenced by reduced GFAP-positive area in cornu ammonis 3 (CA3) (24%, pB=0.026) and dentate gyrus (DG) (19%, pB=0.027) regions, and elevated cellular senescence marker p19Arf specifically in DG (69%, pB=0.033) and CA3 (27%, pB=0.024). The inverse relationship between hnRNPA1 reduction and p19Arf elevation suggests a potential mechanistic link between RNA dysregulation and senescence induction, with pronounced vulnerability in …

Toxin-Like Proteins In The Venom Of Drosophila Parasitoids, Lady V. Cardenas

Dissertations and Theses

The figitid parasitoid wasps of Drosophila are gaining importance in agriculture due to their ability to kill the resilient soft-fruit pest Drosophila suzukii. Their success and infection strategies vary, and the mechanisms underlying these differences are largely unknown. Some of their venom proteins have been shown to be important in suppressing host defense. Here, we report that Ganaspis brasiliensis, a parasitoid of D. suzukii survives well on Drosophila yakuba, a host species with a strong cellular immunity, and infected flies are unable to mount a strong immune response. To predict possible toxin-like proteins in Ganaspis venoms that might suppress cellular …

Automated Thermo-Mechanical Therapy For Immediate Relief In Chronic Non-Specific Lower Back Pain (Cnslbp): A Randomized Controlled Trial, Kyle V. Donnery

Dissertations and Theses

Objective: Chronic non-specific lower back pain (cNSLBP) is a prevalent and disabling condition, imposing a substantial socioeconomic burden due to high healthcare costs and productivity losses, with limited accessible and effective long-term treatment options. Automated Thermo-mechanical Therapy (ATT) is a promising, non-drug intervention that leverages innovative technical advances to provide multimodal pain relief, offering accessibility and low-cost delivery. This study tested ATT for immediate pain relief in individuals with cNSLBP in a single-session, double-blind, randomized controlled trial.

Methods: Forty participants with cNSLBP were randomly assigned to receive either active ATT (n=20) or control ATT (n=20) in a 40-minute session. The …

Heightened Menopausal Symptoms Mediate The Associations Between Stress And Depressive Symptoms Among Midlife Women, Nicole Logan, Janis Gaudreau, Bridget Owens, Brietta M. Oaks, Christie L. Ward-Ritacco, Natalie J. Sabik

Kinesiology Faculty Publications

Objectives:

Investigate associations between stress, cortisol, menopause symptoms, and depression in a sample of midlife women. Because stress has been associated with greater menopause symptoms, we examined this as a mediator for the association between stress and depressive symptoms.

Methods:

Data from a cross-sectional study of 118 women (40-64 y old) were analyzed. Participants completed in-person visits and self-reported questionnaires, including the Menopause-Specific Quality of Life questionnaire, the Perceived Stress Scale, and the Center for Epidemiological Studies Depression Scale. Saliva samples were collected at 4 intervals upon waking (wake, 30 min, 45 min, and 60 min after waking), …

Training Set Augmentation And Harmonization Enables Radiomic Models To Detect Early Onset Of Lung Cancer, Claire Huchthausen, Menglin Shi, Gabriel L.A. Sousa, James Larner, Einsley Janowski, Jonathan Colen, Krishni Wijesooriya

Data Science Faculty Publications

Radiomics-based machine learning models have the potential to detect lung cancer at inception from CT scans and transform patient outcomes. Low malignancy rates in early-development pulmonary nodules (PNs) and variable image acquisition hinder development of clinically applicable radiomics-based early detection models. To address these challenges, we augmented training using later-development PNs and harmonized for acquisition effects. We first trained machine learning models to predict PN malignancy using radiomic features from scans of early-development benign and malignant PNs (n = 187) harmonized using ComBat. Observing near-chance performance, we augmented training with later-development benign and malignant PNs (n = 225). We evaluated …

Education In Death: The Post-Mortem Life Of Academic Collections, Alexis Blanche Bunce

Electronic Theses and Dissertations

Florida Atlantic University has a skeletal teaching collection made up of nine disarticulated individuals. Like other anatomical skeletal collections housed in universities, FAU’s collection has unknown origins. With the current shift in bioarchaeology, it is important to take any steps necessary towards a more ethical practice and properly answer for the unethical practices that led to countless collections being obtained without consent. Keeping proper documentation should always have been a necessity, but moving forward, instructors can introduce curation taphonomy forms into their routine documentation. I drafted and tested these forms on five of the nine skeletal individuals in FAU’s collection …

Population Genetics Of Shallow And Mesophotic Corals And Sponges In The Gulf Of Mexico And Florida, Ryan J. Eckert

Electronic Theses and Dissertations

Population genetic analyses provide critical insights into biodiversity and resilience on coral reefs. This dissertation investigated the genetic connectivity and cryptic diversity of multiple foundational reef species, the corals Stephanocoenia intersepta, Orbicella faveolata, Montastraea cavernosa, and the sponge Xestospongia muta, across shallow and mesophotic reefs in the Flower Garden Banks National Marine Sanctuary (FGBNMS) and across marine protected areas on the Florida Reef Tract. Using a reduced representation genotyping approach, 2bRAD-seq, we generated genome-wide single nucleotide polymorphism (SNP) datasets for each species to assess patterns of population structure across regions and depth zones. Analyses uncovered cryptic lineages …

Mapless Autonomous Navigation Using Monocular Vision, Sai Digvijay Neelam

Electronic Theses and Dissertations

This thesis investigates monocular vision-based navigation for autonomous ground robots in indoor environments. It explores the effectiveness of mapless navigation strategies using image inputs and evaluates both modular and end-to-end deep learning techniques. A comprehensive implementation pipeline was developed on a Clearpath Dingo robot, comparing the approaches: classical optical flow (Farneback), modular deep learning with motion planning, and an end-to-end model.

The modular methods involve predicting region-wise obstacle depths using a ResNet 18 based model trained on a custom indoor dataset, followed by a motion planner. The end-to-end approach leverages a ResNet-18 architecture to jointly predict steering angles and collision …

Spot (Smart Position And Temperature) Tagging Reveals Environmental Factors That Shape Blacktip Shark (Carcharhinus Limbatus) Annual Migrations., Isaac Tuszynski

Electronic Theses and Dissertations

Blacktip sharks (Carcharhinus limbatus) in the Western Atlantic migrate annually to spend the winter in waters off the coast of southeastern Florida. In the spring, these sharks migrate north to waters ranging as far north as Long Island, New York. This study was based on spatial data collected by SPOT (Smart Position and Temperature) tags deployed on blacktip sharks from 2017 to 2024. The data from the tags were used to investigate the offshore extent of the migration, the thermal preferences of these sharks, and which environmental variables can be used to predict their latitudinal distribution. Most blacktip detections were …

Mental And Physical Health, Impulse Control, And Intimate Partner Violence Within A Veteran Sample, Hannah L. Grigorian, Helen P. Hailes, Kathleen Palm Reed, Erin D. Reilly

Psychology

Introduction: Psychiatric (e.g., PTSD, alcohol use disorder) and physical issues (e.g., chronic pain, sleep problems) are robustly associated with the use of intimate partner violence (IPV). These chronic conditions can amplify the likelihood of IPV use by increasing perceived threat, poor relationship quality, and negative affect while simultaneously decreasing the ability to inhibit violent behavior. However, the research in this area has largely been examined in limited samples or by examining a single chronic condition above diagnostic cut-offs or specific dual diagnosis (e.g., PTSD and alcohol use disorder). Further, potential mechanisms of action such as impulse control difficulties are rarely …

Dynamic Quantile Positioning: A Visual Approach To Financial Ratio Benchmarking Against Industry Peers, Wojciech Kuryłek

Studia i Materiały Wydział Zarządzania Uniwersytet Warszawski

Purpose: This paper introduces an innovative visualization method for financial ratio benchmarking that enables comprehensive evaluation of a company’s financial performance relative to industry peers, addressing the challenge of information overload in financial analysis.

Design/methodology/approach: The method analyses data from nearly 200,000 Polish companies classified by PKD codes (aligned with NACE Rev. 2). It evaluates 14 financial ratios across five categories: sales characteristics, profitability, financial leverage, liquidity, and working capital. Each ratio is mapped against industry distributions divided into five quantiles ranging from ‘far below average’ to ‘far above average’. The visualization displays current and previous year positions …

Documenting The Effects Of Laboratory Sorting In Zooarchaeology: Lessons Learned From The Čḯxwicən Project, Kristine Bovy, Virginia L. Butler, Michael A. Etnier, Sarah K. Campbell

Sociology and Anthropology Faculty Publications

Zooarchaeologists routinely analyze assemblages that were initially sorted into major animal type (birds, mammals, fish, invertebrates) by students or lab technicians with varied backgrounds in zooarchaeology. Sorting errors are probably made in this initial phase, which can affect taxonomic representation and understanding of human–animal relationships. Recent study of the immense faunal assemblage (over 1 million NSP [Number of Specimens]) from Čḯxwicən (45CA523), a 2,700-year-old Lower Elwha Klallam village located on the coast of Washington (USA), allows us to systematically analyze trends in sorting errors. For example, 22.6% of the bird bones included in our sample were initially missorted into other …

The Effect Of Huntington’S Disease On The Mechanical And Electrical Properties Of Red Blood Cells, Liliana Ponkratova

Electronic Theses and Dissertations

Huntington’s disease (HD) has an impact on brain tissues and can alter the biochemical properties of the peripheral blood. Evidence in existing literature suggests that peripheral mutant Huntingtin protein may be involved and deteriorate HD. Red blood cells (RBCs), being the most abundant type of cells in the peripheral blood, can show detectable changes in their biophysical properties due to subtle changes in cell membranes. These changes can offer a minimally invasive means to track the progression of the disease. The transgenic line R6/2 is used as the disease model. Utilizing the electro-deformation spectroscopy, we measured membrane permittivity, cytoplasm conductivity, …

Quackery Unmask’D: Defining Quackery In English And American Vernacular Medical Works, C. 1600-1800, Katherine Rose Horan

Electronic Theses and Dissertations

This thesis argues that, from 1600 to 1800, healers in both England and America conceptualized quackery through an evolving understanding of what made a medical practitioner “acceptable.” Through a close examination of vernacular medical print published in both England and America throughout the seventeenth and eighteenth centuries, this thesis complicates earlier understandings of quackery as being disconnected from politics and social biases. Instead, medical authors used social position—specifically gender, race, and religion—and medical philosophy as ways to identify quacks. In England, the Royal College of Physicians used quackery to delegitimize their opponents, while critics of the College did the same. …

Lis1 Depletion In Adult Mouse Projection Neurons Causes Neurodegeneration And Severe Neurological Phenotypes, Anne Ventrone

Theses and Dissertations

Proper LIS1 function is crucial for human brain development, as mutations in LIS1 lead to lissencephaly, a severe neurodevelopmental disorder caused by defective proliferation, differentiation and migration of neural precursors. Our understanding of LIS1's functions after brain development is limited. LIS1 regulates cytoplasmic dynein 1 (dynein), an essential microtubule motor protein in cell division and migration, but also a cellular transport motor. We previously showed that tamoxifen (TX)-induced global knockout of LIS1 using a Cre/Lox system (Act-Lis1iKO) in young adult mice results in severe neurological defects and rapid lethality. This strongly supports LIS1's critical post- developmental role, but the underlying …

Attachment Technique As Orthodontic Aligner Retention Reinforcement: An In Vitro Study, Riandri C. Runizar, Retno Widayati, Miesje K. Purwanegara, Sugeng Supriadi, Giri W. Alam, Galih Taqwatomo

Journal of Dentomaxillofacial Science

No abstract provided.

Exploring The Link Between Bmi, Oral Health, Salivary Flow And Veillonella Parvula Among Adolescents In An Islamic Boarding School In Indonesia, Putri G. Asturini, Eva Fauziah, Mochamad F. Rizal

Journal of Dentomaxillofacial Science

No abstract provided.

Euphorbia Tirucalli Leaf Extract Induces Apoptosis And Inhibits Cell Migration In Hsc-3 Tongue Cancer Cells, Imelda Ongkiwijaya, Rahmi Amtha, Ferry Sandra, Muhammad I. Rizal, Armelia S. Widyarman, Widya Lestari

Journal of Dentomaxillofacial Science

No abstract provided.

Opg And Rankl Expression Of Bone Remodelling After Application Of Stichopus Hermanii In Cavia Cobaya, Bahruddin Talib, Asmawati Amin, Astri A. Aziz, Probo D. Putra, Mohammad D. Utama, Alqarama M. Thalib, Aryadi Arsyad, Delvi S. Reni

Journal of Dentomaxillofacial Science

No abstract provided.

Advancing Oral Health Through Multidisciplinary Innovation: From Molecular Insights To Equitable Care - An Editorial Review, Hasanuddin, Acing H. Mude, Muhammad Ikbal, Erni Marlina, Muhammad Ruslin

Journal of Dentomaxillofacial Science

No abstract provided.

Comparison Of Four Modified Methods Of Ligation Induction Of Periodontitis In Wistar Rat Model: A Pilot Study, Rio Simanjuntak, Budi, Pitu Wulandari, Martina Amalia, Denny Satria

Journal of Dentomaxillofacial Science

No abstract provided.

The Effectivity Of The Combination Of Tricalcium Silicate Cement And Galam Leaf Extract (Melaleuca Cajuputi Subsp. Barlow) As Direct Pulp Capping Materials Reviewed From Vegf, Fgf-2, And Tgf-Β: A Systematic Review, Sherli Diana, Irene E. Rieuwpassa, Juni J. Nugroho, Rasmidar Samad, Risfah Yulianty, Nurhayaty Natsir

Journal of Dentomaxillofacial Science

No abstract provided.

Effectiveness Of Gelatin Extracted From Mackerel Bone (Rastrelliger Sp) On Cell Count In Wistar Rats Mandibular Bone Healing-In Vivo, Isnandar, Gostry A. Dohude, Hendry Rusdy, Muhammad F. Lubis, Lokot D. Lubis, Kevin Marpaung, Monica L. Romauli, Aulia I. Sari

Journal of Dentomaxillofacial Science

No abstract provided.

Analysis Of Calcium-Phosphorus Ion Release And Biocompatibility Of Scaffold Hydroxyapatite Gypsum Puger And Cassava Starch (Manihot Esculenta Crantz) As Bone Graft Secure In Vitro Material, Amiyatun Naini, Zainul Cholid, Dessy Rachmawati, Agus Sumono, Karin Annisa, Dina Carlina, Fx. Ady Soesetijo

Journal of Dentomaxillofacial Science

No abstract provided.

Surgical Correction Of Multiple Malunion Fracture In The Mandible: A Case Report, Vera Julia, Amirul I. Hiroshi, Arbi Wijaya, Ditha Noviantika, A. Surya Darma

Journal of Dentomaxillofacial Science

No abstract provided.

Investigating The Lyoprotective Properties Of An Antifreeze Protein From A Broadleaf Desert Shrub, Alexzandria Sheppard

Honors Theses and Capstones

Lyophilization, or freeze-drying, is an important preservation method for protein-based products, such as protein pharmaceuticals. However, the process introduces both freezing and drying stresses that can harm proteins. Here, we have studied the efficacy of AnAFP, a dehydrin-like antifreeze protein isolated from the broadleaf desert shrub Ammopiptanthus nanus, in reducing enzyme damage during freeze-drying, or lyophilization. We have shown that AnAFP can protect the model enzyme lactate dehydrogenase (LDH) from both freezing and dehydration damages during lyophilization with similar or better efficacy than 10% w/v sucrose and superior to that of another known antifreeze protein.