Digital Commons Network^™

The Financial Stresses That Affect Athletic Training Students: A Qualitative Investigation, C Kuehner-Boyer, E León Zaragoza

Clinical Practice in Athletic Training

Introduction: A recent survey examining barriers that affect athletic training students found that financial-related barriers created significant stress for students in professional athletic training programs. The need to work while attending a professional athletic training program was the highest reported barrier with 54.82% of respondents indicating that this was a barrier for them during their program. Beyond the overall reporting rate, the need to work while completing a professional athletic training program was indicated by athletic training students to be the barrier that they encountered the most frequently with respondents reporting that this was a stress for them between monthly …

Characteristics Of Athletic Trainers That Are Satisfied And Dissatisfied With Their Compensation, K Ef Mair, J P. Young, L E. Eberman

Clinical Practice in Athletic Training

Introduction: Job satisfaction among athletic trainers (ATs), particularly in relation to compensation, is a critical factor influencing retention and career fulfillment. Examining the factors linked to earnings satisfaction may offer insight into how workplace conditions can be improved to better support ATs. The purpose of our study was to investigate the attributes that distinguish ATs content with their compensation from those who are dissatisfied. Methods: We used a cross-sectional, web-based survey to gather AT compensation data, of which 1,887 participants responded to a question regarding their satisfaction with compensation. Respondents were divided into two groups based on their satisfaction with …

Enhancing Clinic Efficiency: A Quality Improvement Initiative For Postoperative Patient Care In An Outpatient Orthopedic Physician Practice Setting, D Stepan, T Jp Greffly, R M. Williams

Clinical Practice in Athletic Training

Introduction: Following orthopedic surgery, patient post-operative (post-op) visits are deemed global surgical observations where day 00 to day 90 are appointments that cannot be billed. Patients are typically seen 3 times during this global period. Thus, the outpatient clinic needs to have non-billable time slots each day for these patients. The current scheduling model double books patients every 15 minutes, with the physician being the primary provider seeing patients for post-op visits. Therefore, the clinic has demonstrated inefficiencies with scheduling these patients while having sufficient appointments available for billable patients. This quality improvement initiative aimed to decrease post-op patient visits …

Factors In Teacher Turnover Within A Nonpublic Special Education Setting, Sarah Wilson

Walden Dissertations and Doctoral Studies

The persistent turnover among special educators poses significant challenges to the quality of education provided to students with disabilities. The problem addressed in this study was the significant rate of turnover of special education teachers in a nonpublic special needs school on the east coast of the United States. Guided by Maslow’s theory of motivation and hierarchy of needs, the purpose of this basic qualitative study was to investigate the experiences of special education teachers and factors that influenced their decision to remain within the classroom environment. Eight special educators participated in semistructured interviews sharing the experiences they perceived as …

Fs Agenda 2025-02-19, Northern Illinois University

Faculty Senate Archives

No abstract provided.

Modeling Covid-19 Spread And Effects Of Non-Pharmaceutical Interventions On A College Campus, Jakob Kotas, Priscilla Perey Ratonel

CODEE Journal

We consider an extension to the classical SIR compartmental model from mathematical epidemiology as applied to the spread of COVID-19 on a college campus. While the classical SIR model does not allow for recovered individuals to lose immunity, we alter the equations to allow for such (due to the rise of new variants), leading to a SIRS-type model. We study the system of ODEs analytically and through numerical simulation. Finally we discuss a quantitative approach for how college administrators can decide when to implement stricter non-pharmaceutical interventions (social distancing, mask mandates, quarantine, etc.) to eradicate the infection from the campus …

The Correlation Between Temporomandibular Disorder (Tmd) And Vitamin D Deficiency, Iris Kim, Claudia Freitas

Annual Research Symposium

No abstract provided.

Investigating Fetalgro Ex As An Alternative To Fetal Bovine Serum In Supplementing Cell Culture Growth, Porter Fife

Annual Research Symposium

No abstract provided.

1 Studying The Determinants Of Successful Aging: Diet, Lifestyle, And Social Relations In Egypt, Fayrouz Shaltout

Theses and Dissertations

Abstract

Background

The global population is aging rapidly, with projections indicating that by 2050, one in six people will be over the age of 65. In Egypt, the aging population, particularly those aged 60 and above, is expected to grow significantly, posing a growing public health concern. Unhealthful diets (that are associated with overweight and obesity), are one of the main reasons associated with non-communicable diseases (e.g., diabetes and cardiovascular diseases) are major risk factors for poor aging outcomes. Despite this, there is limited research on the specific determinants of successful aging (SA) in Egypt, especially among individuals aged 50 …

Terminator: A Software Package For Fast And Local Optimization Of His-Tag Placement For Protein Affinity Purification, Rokas Gerulskis, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

Although the use of affinity tags can greatly improve purification of expressed enzymes, the placement of affinity tags can significantly impact the expression, solubility, and function of recombinant proteins. To facilitate the optimal design of 6xHis-tagged constructs for protein purification, we developed Terminator, a Python-based software package, which takes a UniProt ID or existing protein sequence as input, identifies related sequences, maps sequence conservation retrieved from ConSurf onto protein 3D structures retrieved from the PDB and SWISS-MODEL, and analyzes proximity to cavities and functional sites to recommend the N- or C-terminus for placement of 6xHis fusion tags 86-100% accuracy in …

In-Silico Modeling And Characterization Of Kcc2 Protein Interaction With A Small Molecule Direct Agonist Identifies Potential Binding Sites For Modulating Behaviors Associated With Substances Of Abuse, William Hai Dang Ho, Alfred Amendolara, Kenyon Mitchell, Jaden Miner, Ruth Northcott, Braxton Bingham, Andrew J. Payne

Annual Research Symposium

Purpose

KCC2 is a potassium-chloride cotransporter that plays a critical role in neuronal function by regulating GABAergic signaling via chloride gradients. Maintaining this concentration gradient is crucial for balancing excitation and inhibition in the brain. While KCC2 dysregulation has been implicated in epilepsy and seizures, recent studies suggest that KCC2 inhibition results in phenotypes mirroring those seen in chronic opioid dependence. As such, increasing evidence support KCC2 being a potential therapeutic target for modulating behaviors associated with substances of abuse. Currently, only a few direct small molecule agonists against KCC2 have been reported, and no definitive active site on the …

February 19, 2025 (Vol. 109, No. 19), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.

Zno Nanowires For Biosensing Applications, G.M. Mehedi Hossain, Daniel Garza, Emilio Chavez, Ahmed Hasnain Jalal, Fahmida Alam

Electrical and Computer Engineering Faculty Publications

Zinc oxide Nanowires (ZnO-NWs) are promising biosensor materials and hold the key to overcoming challenges in the field. This chapter provides an introductory overview of biosensing technology, focusing on the fundamental principles and comparing ZnO-NWs with other nanostructures regarding the surface area, reactivity, electrical properties, charge transport behavior, optical, magnetic, and piezoelectric properties, and mechanical flexibility. Providing the synthesis and characterization methods, ZnO-NWs’ biosensing processes are also elaborated on surface modification for selectivity, integration with microfluidic systems, enhancing signal transduction, and connecting with biological elements like enzymes, antibodies, and DNA. The chapter also discusses the applications of ZnO-NWs-based biosensors in …

Silencing Faf2 Mitigates Alcohol-Induced Hepatic Steatosis By Modulating Lipolysis And Pcsk9 Pathway, Nazmul Huda, Praveen Kusumanchi, Yanchao Jiang, Hui Gao, Themis Thoudam, Ge Zeng, Nicholas J. Skill, Zhaoli Sun, Suthat Liangpunsakul, Jing Ma, Zhihong Yang

School of Medicine Faculty Publications

BACKGROUND: Chronic alcohol consumption leads to lipid accumulation, oxidative stress, cellular damage, and inflammation in the liver, collectively referred to as alcohol-associated liver disease (ALD). FAF2/UBXD8/ETEA (Fas-associated factor 2) is a ubiquitin ligase adaptor protein that plays a crucial role in the ubiquitin-mediated degradation of misfolded proteins in the endoplasmic reticulum. A recent genome-wide association study indicated an association between FAF2 and ALD; however, the exact contribution of FAF2 to ALD pathogenesis remains unclear. METHODS: FAF2 was knocked down using AAV-delivered shRNA in C57/BL6 mice. Mice were subjected to a chronic-plus-single binge ethanol feeding (NIAAA) model. Nine hours after gavage, …

A Bibliometric Study Of Astronomy And Geoscience Doctoral Dissertations, Nora Boyle, Mary Schlembach

Faculty Journal Articles

A bibliometric analysis was conducted over the bibliographies of astronomy and geology doctoral dissertations written between 1970 and 2020 in order to review the document types that are utilized and cited. An investigation was made of various cited reference ages and how cited references in dissertations have evolved with the advent of electronic resources and preprint services. Our study examined 50 astronomy and 50 geology dissertations with 10 dissertations selected from each decade (n = 100). Results measured included 13,475 total references and the study found that references to journal articles increased, and book citations have decreased in both …

Therapy Combining Sorafenib And Natural Killer Cells For Hepatocellular Carcinoma: Insights From Magnetic Resonance Imaging And Histological Analyses, Zigeng Zhang, Guangbo Yu, Aydin Eresen, Qiaoming Hou, Sha Webster, Farideh Amirrad, Surya M. Nauli, Zhuoli Zhang

Pharmacy Faculty Articles and Research

Background/Objectives: Hepatocellular carcinoma (HCC) remains a significant global health issue due to its high mortality rate and resistance to standard treatments. Sorafenib, the first-line systemic therapy for unresectable HCC, shows limited effectiveness due to resistance and severe side effects. Recent studies suggest that combining sorafenib with immunotherapy, particularly natural killer (NK) cells, may improve treatment outcomes. Methods: This study examined the effectiveness of sorafenib combined with NK cells pretreated with interleukin-12 (IL-12) and interleukin-18 (IL-18) in a rat HCC model. Tumor progression and treatment outcomes were assessed using MRI and histological analysis. Results: The results show that …

Study To Understand The Effects Of Biofouling And Corrosion On Underwater Munitions: Implications For Risk Management And Resource Allocation, Center For International Stabilization And Recovery, Fenix Insight

Global CWD Repository

The project's primary objective is to understand the impacts of the underwater environment on munitions as a means to identify the residual risk these munitions pose, so people undertaking detection and clearance efforts can reliably assess operational risk and make informed decisions.

Multiple Hypothesis Testing Under Dependence, Nabaneet Das

Doctoral Theses

We have examined various aspects of multiple hypothesis testing under dependence. Traditional algorithms designed to control the error arising from multiplicity become severely conservative when the hypotheses exhibit positive dependence, resulting in a loss of power. There is a paucity of literature explicating the behaviour of traditional algorithms when the hypotheses are dependent. In the realm of multiple testing, a popular multiplicity correction is the Bonferroni correction, which is perhaps the oldest classical approach for controlling the Family-Wise Error Rate (FWER) at a desired level, regardless of dependence among hypotheses. However, under the global null and equicorrelated normal model, the …

Correlation Of Gnas Mutational Status With Oncologic Outcomes In Patients With Resected Intraductal Papillary Mucinous Neoplasms, Julia S. Evans, Kylee Shivok, Hui Hsuan Chen, Eliyahu Gorgov, Wilbur Bowne, Aditi Jain, Phd, Harish Lavu, Charles J. Yeo, Avinoam Nevler

SKMC Student Presentations and Publications

Background: Intraductal papillary mucinous neoplasms (IPMNs) are pre-malignant pancreatic lesions that may progress to invasive pancreatic ductal adenocarcinoma (PDAC). IPMN-associated invasive carcinoma (iIPMN) has been associated with more favorable survival outcomes compared to non-iIPMN-derived PDAC. Here, we aim to investigate the genetic landscape of IPMNs to assess their relevance to oncologic outcomes. Methods: This retrospective study used a large single-institution prospectively maintained database. Patients who underwent curative-intent pancreatic resection between 2016 and 2022 with histologically confirmed diagnosis of IPMN were included. Demographic, pathologic, molecular, and oncologic outcome data were recorded. Kaplan–Meier survival analyses were performed. PDAC data from public genetic …

Phylogenetic Allometric Scaling Of Near Basal Breathing Frequency In Terrestrial, Semi-Aquatic And Aquatic Mammals, Andreas Fahlman, Elliot Stielstra, Ethan Wilstermann, Simon Rylaarsdam, Josefin Larsson, Guillermo J. Sanchez -Contreras, Suguru Higa, Gonçalo N. Marques, Malgosia Kaczmarska, Jason Somarelli, Stacy L. De Ruiter

University Faculty Publications and Creative Works

We measured the BASAL breathing frequency following an overnight fast in adult,non-pregnant/non-lactating, inactive mammals ranging in body mass from 15 to5520 kg. The data included results from 338 individual animals from 34 speciesthat were divided into terrestrial, semi-aquatic (Otariidae and Phocidae) and aquaticmammals. Following attempts to limit the collection of breathing frequency usinga basal definition and to correct the analysis phylogenetically, our results suggestthat there are differences in the allometric mass-exponent between terrestrial andaquatic/semi-aquatic mammals. An allometric regression model, whereby both bodymass and breathing frequency were transformed using log10 , suggested that theallometric mass exponent for terrestrial mammals (−0.303) was …

Aging Is Associated With Decreased Lactobacillus And Increased Cervicovaginal Inflammation In Canadian Women, Ha T. Dang, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Hossaena Ayele, Alicia R. Berard, Adam D. Burgener, Christina Farr Zuend

Faculty Scholarship

Problem: Aging is characterized by a general dysregulation of systemic immune responses that increases susceptibility to infections and malignancies. Immune cells in the female genital tract (FGT) are regulated by sex hormones, but little is known about the impact of aging and menopause on immunology in the FGT. Method of Study: This study conducted an age-focused sub-analysis of cervicovaginal samples collected from 47 women enrolled in the Vaginal Mucosal Systems study in Winnipeg, Canada. Paired cervicovaginal lavage and cervical cytobrush were collected and analyzed by Luminex cytokine array, mass spectrometry based metaproteomics, metabolomics, and high dimensional flow cytometry. Results: The …

The Metaphysics Of Time Within Physics, Mohamed Ahmed

Theses and Dissertations

The starting point of this thesis is to shed some light on the metaphysical nature of time by reflecting on the physics of time. The aim of this approach is not to [dis]prove or defend a metaphysical position but rather to elucidate the metaphysical position that underlies [or is compatible with] our best scientific theories. This task will be demanding, not only because our best theories may carry different interpretations of their underlying temporal structure but also because there seems to be a conceptual conflict/incompatibility between the notion of time in relativity and quantum mechanics, which are the two major …

Mir-125a-3p And Its Targets: Promising Biomarkers For Ovarian, Liver, And Breast Cancers, Offering A Beacon Of Hope For More Effective Diagnosis And Treatment Strategies, Eman Kamaleldien Anwer

Theses and Dissertations

Cancer is a worldwide health problem with various genetic and epigenetic alterations, resulting in disease heterogeneity. Effective diagnostic, therapeutic, and monitoring markers have been determined recently; however, new diagnostic, prognostic, and therapeutic markers are needed. MicroRNAs (miRNA), short non-coding RNAs, have a highlighted role in cancer progression, migration, and programmed cell death. Our study aims to investigate the significance of miR-125a-3p and its downstream targets in breast (BRCA), hepatocellular (HCC), and ovarian (OVCA) malignancies and their possibility as diagnostic biomarkers and targets for therapeutic agents. Bioinformatics and online tools were used to determine the miRNA-predicted downstream targets, analyze GEO datasets, …

Predicting The Indirect Cost Of Construction Projects In Egypt: An Artificial Neural Network Approach, Aya Effat

Theses and Dissertations

Cost estimation is one of the vital processes in construction management that needs to be done early in any project in order to determine the project's budget. The accuracy of the cost estimate is a key factor in the success of construction projects since it enables project managers to successfully control the project’s expenses. Construction costs mainly consist of direct cost and indirect cost. Generally, indirect costs can be categorized into two types: site overheads and general overheads. In a construction project, overheads, particularly site overhead costs, make up a considerable portion of a contractor's budget. Accordingly, accurately estimating the …

The Legal Framework Of Foster Care In Egypt: A Gender Analysis Of Alternative Families And Patrilineal Structures, Amira Fadel

Theses and Dissertations

The thesis explores women’s legal representation and agency over their non-biological children, and how the foster care system in Egypt either reinforces or deconstructs existing gender roles. Hence from a sociological perspective, it accounts for foster and alternative care laws in Egypt and the amendments thereof, to examine social relationships against the backdrop of more conventional, biological families, and kinship relations. In simple terms, studying foster and alternative care laws in Egypt is crucial to grasp how non-biological families are shaped in comparison to the more conventional bonds within biological families and traditional kinship relations, while accounting for the Christian …

Meet The Spring '25 Climate Action Clinic Cohort, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

The Role Of Non-Coding Rnas As An Innovative Therapeutic Tool For Hepatocellular Carcinoma, Nabila Mohamed Hosni El Kramani

Theses and Dissertations

Hepatocellular carcinoma (HCC) is the second lethal cancer worldwide, with over 60 million new patients added annually. Hepatitis B infection and toxins, e.g., aflatoxin, contribute to the incidence of HCC. Egypt and China show the highest prevalence of viral hepatitis and HCC in the world.

Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts larger than 200 nucleotides. These transcripts work at the transcriptional, post-transcriptional, and epigenetic levels to regulate gene expression by interacting with various biomolecules, such as RNA, DNA, and proteins. They serve essential functions in chromatin remodeling and cell survival, differentiation, and proliferation. The role and biological interactions of …

Identification Of Novel Genetic Biomarkers Linked To The Prodromal Stage Of Parkinson’S Disease (Pd) Patients, Marwa Tawfik Badawy

Theses and Dissertations

Background and Objective: The early diagnosis of neurodegenerative diseases, such as Parkinson's disease (PD), is particularly challenging because symptoms appear only after significant neuronal damage has already occurred. This study is utilizing variant call format (VCF) analysis to identify genetic variants and novel genes that could serve as early prognostic markers for prodromal PD. Materials and Methods: Data were sourced from the Parkinson's Progression Markers Initiative (PPMI), focusing on prodromal patients with gVCF data from the 2021 cohort. The study included 304 participants, comprising 100 healthy controls, 146 individuals with prodromal genetic indicators, 21 individuals with prodromal hyposmia, and 37 …

Integrating Planetary Health Into Public Health Education For Sustainable Healthcare Practices, Eman Aboualy

Theses and Dissertations

Introduction: Integrating planetary health in public health education became an urgent global call for action since the WHO announced that the climate change and environmental degradation are the most threat facing the humanity in the recent decades (1). According to that, many countries are developing strategies for counteracting and mitigating the impact of climate change and restore the planetary health. These strategies are including policy drafting and preparing their public health professionals to recognize and address the health effects of environmental change, promote practices for sustainable healthcare. Although Egypt is formulating different policies to cope with and respond to the …

Commensality In The Eateries Of Roman Pompeii, Amaya Yolanda Eckersley

Dissertations and Theses

Despite a nearly 300-year excavation history at Pompeii and many identified eating and drinking establishments, social behavior in these public or semi-public spaces has eluded significant research. Elite Roman literature is the traditional guideline for understanding Roman mealtimes and what they meant for social behavior. This literature, however, fails to accurately represent its sub-elite inhabitants. These sub-elites of Rome largely had their meals prepared outside of their homes. Pompeii is no exception and provides a massive boon for researchers willing to consider archaeological evidence. The buildings and evidence buried at Pompeii have ultimately shown a wide array of tabernae related …