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2025

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An Analytical Study Of Selected Biomechanical Variables And The Accuracy Of Forecourt And Backcourt Shots In Wheelchair Badminton Players, Zina Abdulkareem Abbas, Fatimah Abed Malih Jun 2025

An Analytical Study Of Selected Biomechanical Variables And The Accuracy Of Forecourt And Backcourt Shots In Wheelchair Badminton Players, Zina Abdulkareem Abbas, Fatimah Abed Malih

Modern Sport

The significance of this study lies in analyzing player movement through biokinematic variables using video recording and Kinovea motion analysis software. By investigating selected biomechanical variables, the researchers aimed to improve the accuracy of forecourt and backcourt shots among wheelchair badminton players based on insights derived from this analysis. The findings aim to guide coaches and players by utilizing motion analysis outcomes to enhance training strategies and achieve higher levels of technical performance and athletic accomplishment. The study aimed to describe and analyze the biomechanical variables influencing shot accuracy and identify the relationship between these variables and shot accuracy among …


The Effect Of Boot Camp Training Program On The Development Of Special Strength And Some Biomechanical Indicators Of The Triple Jump In Young Female Athletes, Suaad Abdul-Hussein, Zainab Ali Abdul-Ameer Jun 2025

The Effect Of Boot Camp Training Program On The Development Of Special Strength And Some Biomechanical Indicators Of The Triple Jump In Young Female Athletes, Suaad Abdul-Hussein, Zainab Ali Abdul-Ameer

Modern Sport

The qualitative concept of training experienced athletes is not limited to strength training alone, but extends to general physical conditioning and, ultimately, to special strength training during the specific phases of athletic preparation, depending on the type of sport practiced. Since athletic training should not follow a single, monotonous pattern, the researchers adopted modern Boot camp exercises to develop special strength and biomechanical variables for female triple jump athletes. The study aimed to design Boot camp exercises specifically to enhance special strength and certain biomechanical indicators in young female triple jump athletes, and to identify the impact of these exercises …


The Effect Of Blue Light Filter Lens Glasses On The Occurrence Of Asthenopia Symptoms In Visual Display Terminal Users, Arif Hening Mustikaningrum, Dewi Sumaryani Soemarko, Indah Suci Widyahening Jun 2025

The Effect Of Blue Light Filter Lens Glasses On The Occurrence Of Asthenopia Symptoms In Visual Display Terminal Users, Arif Hening Mustikaningrum, Dewi Sumaryani Soemarko, Indah Suci Widyahening

Occupational and Environmental Medicine Journal of Indonesia

The widespread use of Visual Display Terminals (VDTs) is associated with visual and musculoskeletal complaints, particularly Asthenopia, which may reduce productivity. A 32-year-old female financial worker presented with eye discomfort, including sore eyes, blurred vision, dizziness, and twitching on her left temple, particularly during extended computer use. The symptoms were relieved with rest. Most VDTs now use Light Emitting Diodes, which emit more blue light than LCDs and may cause eye fatigue and disrupt sleep. Currently, blue light filter lenses are available in the market, however, further study of existing scientific publications is necessary to ensure the effectiveness of blue …


The Effort To Improve Students’ Problem-Solving Ability: Physics E-Modules For High School Students, Hidayatullah Hana Putra, Edi Supriana, Nasikhuddin Nasikhuddin, Annisa U. Yana, Suhailee Sohnui Jun 2025

The Effort To Improve Students’ Problem-Solving Ability: Physics E-Modules For High School Students, Hidayatullah Hana Putra, Edi Supriana, Nasikhuddin Nasikhuddin, Annisa U. Yana, Suhailee Sohnui

Jurnal Pendidikan Sains

Physics teachers in Indonesia still face obstacles during learning, such as students who are less active and have difficulty in solving physics problems. The physics learning media used are also still not very interesting and are not based on authentic problem solving. Therefore, this study focuses on the development of PBL-based e-modules on work and energy to improve the physics problem-solving abilities of high school students. This research and development used the ADDIE design and was tested on 90 high school students in High School 1 Sumber Pucung Malang in the 2022/2023 academic year. The questionnaire instrument was used in …


Ethnoscience-Based Science Learning Through Composite Board Making Utilizing Eggshell Waste And Water Hyacinth Fiber (Eichornia Crassipes), Asep Khaidir Arpan, Yulia Sukmawardani, Pina Pitriana, Ade Yeti Nuryantini Jun 2025

Ethnoscience-Based Science Learning Through Composite Board Making Utilizing Eggshell Waste And Water Hyacinth Fiber (Eichornia Crassipes), Asep Khaidir Arpan, Yulia Sukmawardani, Pina Pitriana, Ade Yeti Nuryantini

Jurnal Pendidikan Sains

The demand for boards continues to increase every year, while overexploitation of wood leads to environmental degradation and forest loss. On the other hand, eggshell and water hyacinth waste continues to grow without optimal utilization. This research aims to make composite boards based on eggshell waste and water hyacinth fibers and analyze the potential of ethnoscience in science learning. This research used a qualitative descriptive method with a literature and documentation study approach. The materials used in this experiment are eggshell waste, water hyacinth fiber, and polyester resin. The composite board was made by mixing water hyacinth fiber and eggshell …


Contextual Approach To Improve Problem Solving Skills In Ipas Subject At Elementary School: A Study Development Of Teaching Materials, Nur Hidayah, Sumarno Sumarno, Joko Siswanto Jun 2025

Contextual Approach To Improve Problem Solving Skills In Ipas Subject At Elementary School: A Study Development Of Teaching Materials, Nur Hidayah, Sumarno Sumarno, Joko Siswanto

Jurnal Pendidikan Sains

The objective of this study is to assess the validity, practicality, and efficacy of instructional materials. We refer to this research as research and development, with a focus on the creation of teaching materials. The research design proposed by Borg and Gall consists of six steps: identification of potential and difficulties, data collecting, product design, design validation, design revision, and product trial. The utilized instruments comprise expert and practitioner validity sheets, teacher and student response surveys, and validation sheets for teaching materials and modules, as well as pretest and posttest questions. Experts performed the validity assessment, attaining a score of …


Teaching Materials Containing Kse To Support Character Education In Mathematics Subjects In Elementary Schools, Kunaenah Kunaenah, Rasiman Rasiman, Bagus Ardi Saputro Jun 2025

Teaching Materials Containing Kse To Support Character Education In Mathematics Subjects In Elementary Schools, Kunaenah Kunaenah, Rasiman Rasiman, Bagus Ardi Saputro

Jurnal Pendidikan Sains

The purpose of the study was to determine the validity, practicality, and effectiveness of teaching materials containing KSE to support character education in mathematics lesson content. This study employs a development research approach based on Borg and Gall's research design. The subjects of the study were in class V at public elementary school Kaliboyo. The data collection instruments used were validity sheets, response questionnaires, validation sheets, and observation sheets. The findings show that experts carried out the validity test, achieving a value of 93.30% in the very valid category. The practicality test results were derived from various sources: students' questionnaires, …


Development Of Differentiated Teaching Modules With A Scientific Approach To Improve Elementary School Students’ Science Literacy, Supriyanto Supriyanto, Joko Sulianto, Achmad Buchori Jun 2025

Development Of Differentiated Teaching Modules With A Scientific Approach To Improve Elementary School Students’ Science Literacy, Supriyanto Supriyanto, Joko Sulianto, Achmad Buchori

Jurnal Pendidikan Sains

The study aim is to determine the validity, practicality, and effectiveness of teaching materials. This type of research involves the development and creation of teaching module products. The research design used is ADDIE (Analysis, Design, Development, Implementation, Evaluation). The instruments used are validity sheets for experts and practitioners, teacher response questionnaires, teaching module validation sheets, and pretest and posttest questions. The findings show that experts conducted the validity test, achieving a score of 92.22 in the very valid category. The practicality test was obtained from the teacher questionnaire, which was stated as practical with an average value of 91.25, and …


Determination Of Urinary Metabolites Of Toluene And Xylenes In Paint Workers And Non-Occupationally Exposed Individuals In Saudi Arabia, Ahmad Alturkstani, Radhouane Chakroun, Bassam Jamoussi, Raghad Alhajaji Jun 2025

Determination Of Urinary Metabolites Of Toluene And Xylenes In Paint Workers And Non-Occupationally Exposed Individuals In Saudi Arabia, Ahmad Alturkstani, Radhouane Chakroun, Bassam Jamoussi, Raghad Alhajaji

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Aromatic hydrocarbons such as toluene and xylenes are widely used as solvents in industrial processes, particularly in paint production, despite their known toxicity. Occupational exposure to these chemicals poses significant health risks, especially for workers in the manufacturing and application sectors. The International Agency for Research on Cancer (IARC) has reported an increased cancer risk associated with paint fume exposure, prompting regulatory agencies such as the Occupational Safety and Health Administration (OSHA) and the National Institute for Occupational Safety and Health (NIOSH) to establish exposure limits. In Saudi Arabia, a key player in the petroleum and chemical industries, workers face …


The Effect Of Gum Arabic (Acasia Senegal) As A Natural Prebiotic Supplementation For Broiler Chickens, Mohamed A. M. Mousa, Abeer Rabie Khosht, Ibrahim H. Salim, Ahmed. E. Shamseldeen, Ahmed S. Arafa, Maged A. El-Deeb, Hamdy M. El-Komy, Samia M Mobarez Jun 2025

The Effect Of Gum Arabic (Acasia Senegal) As A Natural Prebiotic Supplementation For Broiler Chickens, Mohamed A. M. Mousa, Abeer Rabie Khosht, Ibrahim H. Salim, Ahmed. E. Shamseldeen, Ahmed S. Arafa, Maged A. El-Deeb, Hamdy M. El-Komy, Samia M Mobarez

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Gum Arabic (GA) belongs to the Fabaceae family and contains indigestible soluble fibers (80--85%) that can be fermented by commensal bacteria to enhance performance, immune response, and intestinal integrity. The aim of this study was to determine the effect of different levels of gum arabic (GA) on overall growth performance, serum biochemical indicators, relative weight of visceral and lymphoid organs, intestinal histomorphology, and selected pathogenic bacteria in broiler chickens. A total of 450 day-old Ross chicks were assigned to four groups, containing 0, 2.5, 5.0, 7.5 and 10.0 g gum arabic along with basal feed for 35 days. Results indicated …


Exploring Phytoconstituents Of Neem Leaf Extract And Its Potential Antimicrobial And In Vitro Anticancer Activities, Omer Hosni Mohamed Ibrahim Jun 2025

Exploring Phytoconstituents Of Neem Leaf Extract And Its Potential Antimicrobial And In Vitro Anticancer Activities, Omer Hosni Mohamed Ibrahim

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

Considering the growing interest in exploring the biologically active chemicals of the neem (Azadirachta indica A. Juss) plant, this current study was designed to explore and characterize the probable phytoconstituents of the methanolic extract of neem leaves using GC-MS analysis. The antibacterial activity of the extract was studied against Agrobacterium tumefaciens, Serratia marcescens, and Acinetobacter johnsonii and its antifungal activity against Rhizoctonia solani, Penicillium italicum, and Fusarium oxysporium. Further, the cytotoxicity was assessed against PC-3, MCF-7, and Caco-2 cancer cell lines, compared with the normal Vero cells, where IC50 and selectivity index for …


Differentiated Teaching Module Using Problem Solving Model: Numerical Ability Of Elementary School Students, Risa Alifatin, Agus Sutono, Ida Dwijayanti Jun 2025

Differentiated Teaching Module Using Problem Solving Model: Numerical Ability Of Elementary School Students, Risa Alifatin, Agus Sutono, Ida Dwijayanti

Jurnal Pendidikan Sains

This study aims to develop a differentiated teaching module using the problem-solving model that is valid, practical, and effective to improve students' numerical abilities. This study uses the ADDIE Model research and development approach. The sample in this study was class III of elementary school Tenggulangharjo as an experimental class totaling 22 students and class III of elementary school Karangtengah as a control class totaling 19 students. Data analysis used the t-test and N-Gain test. The study found that (1) the average validity score of the three parts of the Differentiated Teaching Module was 3.74, which is 93.62%, placing it …


Efektivitas Massage Endorphin Untuk Mengurangi Kecemasan Pada Ibu Hamil Menjelang Persalinan, Widiya Saryani, Dini Nur Alpiah Jun 2025

Efektivitas Massage Endorphin Untuk Mengurangi Kecemasan Pada Ibu Hamil Menjelang Persalinan, Widiya Saryani, Dini Nur Alpiah

Jurnal Fisioterapi Terapan Indonesia

Pregnancy is a biological process involving complex physiological and psychological transitions that demand high adaptability from women, especially approaching childbirth. Anxiety during the third trimester is frequently reported and is associated with increased cortisol secretion, which may negatively impact labor effectiveness. This literature review aimed to synthesize scientific evidence regarding the effectiveness of endorphin massage in reducing anxiety among pregnant women in the third trimester. The review used a systematic approach based on the PICO framework, covering studies published between 2021 and 2025. Databases such as PubMed, Google Scholar, and SINTA were used to identify quasi-experimental studies comparing endorphin massage …


Efektivitas Latihan Aerobik Dalam Mengurangi Gejala Depresi: Literature Review, Putra Adytio Giriyoga, Dini Nur Alpiah Jun 2025

Efektivitas Latihan Aerobik Dalam Mengurangi Gejala Depresi: Literature Review, Putra Adytio Giriyoga, Dini Nur Alpiah

Jurnal Fisioterapi Terapan Indonesia

Depression is one of the most common mental health disorders worldwide and can significantly affect an individual's quality of life. Various treatment approaches have been implemented, with one of the most noteworthy being non-pharmacological interventions in the form of aerobic exercise. This study aims to review the effectiveness of aerobic exercise in reducing depressive symptoms. This research is a narrative literature review, in which 3,610 articles were initially identified and then filtered based on inclusion-exclusion criteria, resulting in 8 articles. After eliminating duplicates, further screening was conducted through critical appraisal. The final selection of 8 articles was reviewed. The findings …


Dynamic Model Of Stunting Incidents And Policies In Padang City, Elsa Yuniarti, Yulhendri Yulhendri, Fitra Arya Dwi Nugraha, Nurhasan Syah, Iswandi Umar, Heldi Heldi, Nabila Azzahra Jun 2025

Dynamic Model Of Stunting Incidents And Policies In Padang City, Elsa Yuniarti, Yulhendri Yulhendri, Fitra Arya Dwi Nugraha, Nurhasan Syah, Iswandi Umar, Heldi Heldi, Nabila Azzahra

Media Kesehatan Masyarakat Indonesia

Stunting remains a significant public health challenge with complex, interconnected causative factors. Traditional static approaches fail to capture the dynamic relationships between environmental, health, and socioeconomic determinants. Dynamic modeling is essential for understanding these multifaceted interactions and developing effective prevention policies. Despite declining trends, Padang City's high prevalance of stunting necessitates urgent, targeted interventions to achieve national targets. This study aims to develop a dynamic model analyzing stunting factors in Padang City and formulate effective prevention policies. A quantitative descriptive method with a dynamic systems approach was employed. Primary data were obtained through stakeholder questionnaires, while secondary data were obtained …


Mapping Trends And Patterns In Tuberculosis And Tobacco Use: Insights From A Bibliometric Analysis Of 25 Years Of Research, Meyi Yanti, Erwani Erwani, Radian Ilmaskal, Masrizal Masrizal, Sohel Rana Jun 2025

Mapping Trends And Patterns In Tuberculosis And Tobacco Use: Insights From A Bibliometric Analysis Of 25 Years Of Research, Meyi Yanti, Erwani Erwani, Radian Ilmaskal, Masrizal Masrizal, Sohel Rana

Media Kesehatan Masyarakat Indonesia

Tuberculosis (TB) and tobacco use represent two of the most pervasive global health challenges, with a particularly profound impact in Low and Middle-Income Countries (LMICs). Although numerous reviews have explored the clinical and epidemiological associations between TB and smoking. A systematic analysis of publication trends is lacking. This study aims to address this gap by providing a comprehensive bibliometric analysis of the intersection between TB and tobacco use, mapping its evolution, key research themes, collaboration networks, and underexplored areas. This study utilized a bibliometric method. Data from 13,876 articles indexed in Scopus were analyzed using RStudio, VOSViewer, and OpenRefine. PLOS …


Lifestyle Activities That Contribute To The Risk Of Stroke In Indonesia: Smoking, Consuming Fatty Foods And Soft Drinks, Janu Purwono, Irwan Budiono, Oktia Woro Kasmini Handayani Jun 2025

Lifestyle Activities That Contribute To The Risk Of Stroke In Indonesia: Smoking, Consuming Fatty Foods And Soft Drinks, Janu Purwono, Irwan Budiono, Oktia Woro Kasmini Handayani

Media Kesehatan Masyarakat Indonesia

Stroke is the leading cause of death and disability in Indonesia, with a high prevalence reported in the Indonesian Health Survey (IHS) 2023. Smoking, consumption of fatty foods, and intake of soft drinks are major risk factors contributing to the increasing incidence of both ischemic and hemorrhagic stroke. This study aims to analyze the effects of smoking habits, fatty food consump-tion, and soft drink intake on stroke incidence in Indonesia using secondary data from IHS 2023. A quantitative design was applied, with chi-square test analysis performed using SPSS. The study population comprised all individuals recorded in the IHS 2023, which …


Determinants Of Food Management Behavior On Food Waste Reduction And Household Food Security Through Expenditure Efficiency And Energy Consumption, Prita Dhyani Swamilaksita, Yayuk Farida Baliwati, Drajat Martianto, Dodik Briawan Jun 2025

Determinants Of Food Management Behavior On Food Waste Reduction And Household Food Security Through Expenditure Efficiency And Energy Consumption, Prita Dhyani Swamilaksita, Yayuk Farida Baliwati, Drajat Martianto, Dodik Briawan

Media Kesehatan Masyarakat Indonesia

Food Waste (FW) in urban households remains a serious issue as it contributes to economic losses, reduced dietary quality, and weakened food security. This study aims to identify the dominant factors influencing food management behavior, FW generation, and their implications for household food security in urban settings. A cross-sectional design was applied with urban households as the study population, and samples were selected using purposive sampling. Data were analyzed using Structural Equation Modeling (SEM) within the framework of the Theory of Planned Behavior (TPB) and Nudge Theory. The results indicate that attitude (β = 0.42; p < 0.01), subjective norm (β = 0.31; p < 0.05), and perceived behavioral control (β = 0.36; p < 0.01) significantly influence intention toward food management. Furthermore, intention strongly predicts actual food management behavior (β = 0.55; p < 0.001), which subsequently reduces FW (β = –0.47; p < 0.001). Reduced FW positively affects both food expenditure efficiency (β = 0.39; p < 0.01) and energy intake adequacy (β = 0.34; p < 0.05), two critical indicators of urban household food security. Behavioral factors play a crucial role in reducing FW and strengthening food security in urban households. Therefore, behavior-based interventions using TPB and Nudge Theory are recommended to be integrated into food education programs, household assistance, and urban food security policies to ensure effectiveness and sustainability.


Analysis Of Students' Creative Thinking Skills In Learning Hydrocarbons By Using Daily Life-Based Practicum Method, Yenni Kurniawati, Laras Dyaz Handayani, Dea Ramadani, Nurhikmah Sari Jun 2025

Analysis Of Students' Creative Thinking Skills In Learning Hydrocarbons By Using Daily Life-Based Practicum Method, Yenni Kurniawati, Laras Dyaz Handayani, Dea Ramadani, Nurhikmah Sari

Jurnal Pendidikan Sains

Creative thinking skill is a competence of the 21st century that is needed very much and needs to be increased by utilizing chemistry in life. This research aimed at analyzing student creative thinking skills in experimental and control groups and finding out the effect of the daily life-based practical work learning method on student creative thinking skills. This research was conducted in the eleventh grade at High School 1 Pekanbaru on the hydrocarbon lesson. The quasi-experimental method was used in this research with pretest-posttest and non-equivalent control group designs. The instruments used in this research were essay tests, observation, and …


Exploring Students’ Perceptions Of Science Laboratory Practices: A Comparative Study Between Rural And Urban Schools, Safrida Dwiningsih, Ina Lestari, Roma Ismi, Sri Wahyu Rahmadina, Masdalena Sinaga, M. Rahmad Jun 2025

Exploring Students’ Perceptions Of Science Laboratory Practices: A Comparative Study Between Rural And Urban Schools, Safrida Dwiningsih, Ina Lestari, Roma Ismi, Sri Wahyu Rahmadina, Masdalena Sinaga, M. Rahmad

Jurnal Pendidikan Sains

This study aims to analyze students' perceptions of the implementation of science laboratory practicums at public middle school 020 Pekanbaru and public middle school 7 Pangkalan Kuras, Riau Province. Using a quantitative survey method, this study involved 75 student respondents. The instrument used was a questionnaire consisting of 26 statements, analyzed descriptively. The results show that students' perceptions of the preparation, implementation, and conclusion stages of the practicum fall into the "good" category, with urban schools having a higher percentage. In conclusion, the implementation of practicums in urban schools is better than in rural schools, bringing attention to the need …


Digital Comic Learning Media (E-Comic) To Increase Student Learning Interest In Reaction Rate Material At High School, Berliana Afsohin Nabila, Achmad Lutfi Jun 2025

Digital Comic Learning Media (E-Comic) To Increase Student Learning Interest In Reaction Rate Material At High School, Berliana Afsohin Nabila, Achmad Lutfi

Jurnal Pendidikan Sains

This study aims to develop digital comic learning media that is effective in increasing students' interest in learning about reaction rate material, focusing on the media's validity, practicality, and overall effectiveness. This research utilizes the research and development method with the ADDIE model. Research instruments were used, including validity sheets to assess the media's validity, student activity observations, and student response questionnaires to evaluate the media's practicality, as well as student interest questionnaires and learning outcomes to measure the effectiveness of the learning media. The findings show that validity results showed a mode score of 4, indicating a very valid …


Analysis Of Misconceptions In Learning Biology Mutation Material At High School, Fitri Hayati Kurnia, Tri Wahyu Agustina, Wahyuni Handayani Jun 2025

Analysis Of Misconceptions In Learning Biology Mutation Material At High School, Fitri Hayati Kurnia, Tri Wahyu Agustina, Wahyuni Handayani

Jurnal Pendidikan Sains

This research aims to analyze student misconceptions regarding mutation material in class XII. The research method uses a descriptive approach with mixed methods, which combines qualitative and quantitative methods. Qualitative data was obtained through interviews with biology teachers, while quantitative data was obtained through questionnaires and essay tests on students. The research results indicate that the material that students like is growth and development, while the material they don't like is gene mutation and genetic material. Students' misconceptions occur due to preconception aspects, associative thinking, and a lack of understanding of genetic concepts. It was found that students' understanding of …


The Prevalence Of Endothelial Nitric Oxide Gene Polymorphisms In Iraqi Patients With Essential Hypertension, Ghufran K Salman, Bassim I Mohammad Jun 2025

The Prevalence Of Endothelial Nitric Oxide Gene Polymorphisms In Iraqi Patients With Essential Hypertension, Ghufran K Salman, Bassim I Mohammad

Al-Qadisiyah Medical Journal

Background: Due to the polygenic character of hypertension, it is particularly challenging to identify the single nucleotide polymorphisms most likely to be linked with essential hypertension and also the connections between certain genes and treatment responses in various ethnic groups. One of important genes is eNOS gene which encode eNOS enzyme that mediate NO production.  Our study involve rs1799983 (G894T) and rs2070744 (T-786C) of eNOS gene. The objective of this observational cross-sectional descriptive study is to examine frequencies of allele of eNOS3 genes. Methods: ninety hypertensive patients were recruited by specialist cardiologist and conducted at AL-Diwaniyah teaching hospital and department …


Gene Profiling And Clinicopathological Features For Prognostic Modeling Of Recurrence In Non-Metastatic Clear-Cell Renal Cell Carcinoma., Xuzhi Yan, Jian Chen, Dianzheng Zhang, Xiaodu Xie, Ziqian Wang, Chongliang Zheng, Junhao Jin, Jing Xu, Qian Yan, Qiuli Liu, Weihua Lan, Jun Jiang Jun 2025

Gene Profiling And Clinicopathological Features For Prognostic Modeling Of Recurrence In Non-Metastatic Clear-Cell Renal Cell Carcinoma., Xuzhi Yan, Jian Chen, Dianzheng Zhang, Xiaodu Xie, Ziqian Wang, Chongliang Zheng, Junhao Jin, Jing Xu, Qian Yan, Qiuli Liu, Weihua Lan, Jun Jiang

PCOM Scholarly Works

BACKGROUND: Accurate risk stratification of renal cell carcinoma (RCC) is critical for selecting the most appropriate treatment options. Existing prognostic systems, which incorporate various clinical and pathological parameters, have limitations in terms of accuracy. However, it remains unclear whether integrating molecular data with clinicopathological features can enhance the identification of high-risk tumors. The objective of this study was to establish a model to predict RCC recurrence by integrating molecular data with clinicopathological features and to evaluate circulating tumor DNA (ctDNA) as a non-invasive prognostic marker.

METHODS: Next-generation sequencing (NGS) was performed on 73 RCC patients, including 54 with clear-cell RCC …


Predicting The Influence Of Aggregate Size And Distribution On Cementitious Concrete Properties: A Review, Innocent J. Macha Jun 2025

Predicting The Influence Of Aggregate Size And Distribution On Cementitious Concrete Properties: A Review, Innocent J. Macha

Tanzania Journal of Engineering and Technology (TJET)

Cement concrete has been in use for centuries as one of the primary construction materials. Its demand in the construction industry is expected to continue for several centuries before the full development of alternative products. However, one of the main areas of research interest is understanding how its constituents can be tailored to make its properties predictable to reduce risks associated with structural failures, reconstruction and reduced durability. These hindrances associated with cementitious concrete result from several attributes, including constituent material characteristics, mixing ratios and workmanship. Understanding the predictability of cement concrete properties requires computer modelling tools to provide reliable …


Integration Of Mechanism-Driven Computational Modeling And Public Data Resources For Chemical Toxicity Assessment, Elena Chung Jun 2025

Integration Of Mechanism-Driven Computational Modeling And Public Data Resources For Chemical Toxicity Assessment, Elena Chung

Theses and Dissertations

Regulatory toxicology depends primarily on animal testing, which limits throughput, mechanistic interpretability, and applicability to human-relevant endpoints. This dissertation presents computational approaches that integrate publicly available bioactivity data with machine learning to support chemical safety evaluation. Oral carcinogenicity was modeled using curated chemicals from the US Environmental Protection Agency’s Integrated Risk Information System (IRIS) and activity data from over 1,900 PubChem assays. Quantitative structure-activity relationship (QSAR) models trained on statistically prioritized assays demonstrated strong predictive performance and were applied to rank the carcinogenic potential of more than 16,000 compounds. Hepatotoxicity was evaluated using a hybrid modeling approach that combined structural …


Understanding The Correlation Between Clinical Severity Of Psoriasis And Quality Of Life Among Patients With Psoriasis, Aziza Ibrahim Abd El Kader, Mohamed Asim Ghazi Jun 2025

Understanding The Correlation Between Clinical Severity Of Psoriasis And Quality Of Life Among Patients With Psoriasis, Aziza Ibrahim Abd El Kader, Mohamed Asim Ghazi

Hilla University College Journal For Medical Science

Background: Patients with psoriasis often struggle with both their bodies and minds, which can make it hard to perform everyday activities. To provide them with the best care and improve their lives, it’s important to determine how much psoriasis affects their ability to function. Aim: was to explore the relationship between psoriasis severity and functional disability among patients with psoriasis.

Methods: A correlational and cross-sectional research design was employed to achieve the current study’s aim. Setting: The current study was carried out at the Kasr Al-Ainy Psoriasis Unit and Dermatology Department. A purposive sample of 150 participants was recruited for …


Investigation Of Some Biochemical Parameters Changes Due To Coronavirus Infections, Lamiaa Al-Maliki, Manaf A. Guma, Mustafa A. J. Alhiti, Shahad M. Ali, Salman Ashraf, Abdel-Raheem M. A. Jun 2025

Investigation Of Some Biochemical Parameters Changes Due To Coronavirus Infections, Lamiaa Al-Maliki, Manaf A. Guma, Mustafa A. J. Alhiti, Shahad M. Ali, Salman Ashraf, Abdel-Raheem M. A.

Hilla University College Journal For Medical Science

Background: Coronavirus infection has been the severest pandemic in recent years. Several biomarkers for direct assessment and rapid diagnosis have been used, such as IgM and PCR.

Objectives: The aim of this study was to investigate the critical biomarkers, either a mineral or an enzymatic inhibition or activation.

Materials and Methods: This study was conducted on COVID-19 patients who were suspected of being infected with the coronavirus, using serum of 25–80 years of age, males. The following biochemical tests (LDH, CK-MB, Ferritin, Mg, Zn, Cu and Ceruloplasmin) were measured at a private laboratory in Baghdad.

Results: The results showed that …


Anti-Lung Cancer Activity Of The Herbal Medicinal Plant Cycas Revoluta, Mohammed Raheem Khraibet, Enas Jawad Kadhim Jun 2025

Anti-Lung Cancer Activity Of The Herbal Medicinal Plant Cycas Revoluta, Mohammed Raheem Khraibet, Enas Jawad Kadhim

Hilla University College Journal For Medical Science

Background: Phytochemicals have demonstrated strong potential in cancer therapy, and several researchers became interested in evaluating the anti-cancer effects of Cycas revoluta, a plant in herbal medicine.

Objectives: The present study examined the anti-proliferative effect of the n-butanol fraction from Cycas revoluta root extract on A549 human lung adenocarcinoma cells.

Materials and Methods: The roots were defatted with n-hexane and then extracted. The reflux technique—Soxhlet extraction with 85% ethanol and 15% distilled water—was then used to obtain the crude extract of the root, which was subsequently fractionated using the solvents chloroform, ethyl acetate, and n-butanol, respectively. Cytotoxicity was evaluated …


Evaluating The Efficacy Of Thymoquinone Against Pseudomonas Aeruginosa In Hospital-Acquired Pneumonia: A Potential Therapeutic Approach, Hadeel S. Alsufyani, Faez M. Zagzoug, Karem Ibrahem Jun 2025

Evaluating The Efficacy Of Thymoquinone Against Pseudomonas Aeruginosa In Hospital-Acquired Pneumonia: A Potential Therapeutic Approach, Hadeel S. Alsufyani, Faez M. Zagzoug, Karem Ibrahem

Journal of King Abdulaziz University: Medical Sciences

Background: The increasing prevalence of multidrug-resistant Pseudomonas aeruginosa presents a significant challenge in clinical microbiology. This study investigates the antimicrobial efficacy of thymoquinone (TQ) against both resistant and sensitive strains of P. aeruginosa, comparing their minimum inhibitory concentrations (MICs) to assess the potential of TQ as a therapeutic agent.

Methods: A total of 40 P. aeruginosa isolates, consisting of 20 resistant and 20 sensitive strains, were obtained from the Microbiology Culture in Clinical and Molecular Microbiology Laboratories at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. The MIC of TQ was determined using the broth microdilution method. Data were analyzed …