Digital Commons Network^™

Tumor Biology And Access To Care And Metastatic Breast Cancer Outcomes, Matthew R. Dunn, Sarah C. Van Alsten, Marc A. Emerson, Katherine Reeder-Hayes, Terry Hyslop, Melissa A. Troester

Kimmel Cancer Center Faculty Papers

PURPOSE: To understand how access to care influences metastatic breast cancer burden (MBC) while accounting for molecular tumor characteristics, and identify interventions to reduce metastatic disease burden.

METHODS: The Carolina Breast Cancer Study is a population-based cohort with invasive breast cancer (diagnosed 2008-2013). Both de novo metastasis (stage IV at diagnosis) and distant recurrence were evaluated (12 years of follow-up. Tumor data were from medical records, pathology reports, and RNA expression data. Social variables and access to care were from participant surveys. Generalized linear models were used to estimate associations of biological and access characteristics with MBC; Cox models were …

Classifying Glaucoma Disease Images Via Deep Neural Network Technique, Maysoon Jaaffar Rahim, Ali Abid Dawood Al-Zuky, Fatin Ezzat Muhy Al-Dean Al-Obaidi

Baghdad Science Journal

A class of eye diseases known as glaucoma refers to a category of eye disease which is often associated with increased intraocular pressure, and can damage the eye by destroying nerve cells in the retina in addition to the eye's optic nerve. The accuracy of diagnosing glaucoma eye disease depends on the knowledge and experience of the ophthalmologist. Therefore, the need for automatic feature extraction from the retinal image is crucial for the diagnosis of glaucoma eye disease. The current article introduces a multi-layer deep neural network model with convolution and classification layers. The originality of the current search focuses …

Managing The Uncertainty Of "Precision" While Navigating Goals Of Care: A Framework For Collaborative Interpretation Of Complex Genomic Testing Results In Critically-Ill Neonates, Donnamaria E. Cortezzo, Katharine Press Callahan, Bimal P. Chaudhari, Elliott M. Weiss, Monica Hsiung Wojcik, Krishna Acharya, Amy B. Schlegel, Kevin M. Sullivan, Jessica T. Fry

Department of Pediatrics Faculty Papers

Each year, many neonates are born with genetic diagnoses that carry a range of prognoses. As the types and availability of genetic testing have expanded, neonatal intensive care units (NICUs) have served as "launching points" for their clinical application. Broad genetic testing has both improved diagnostic precision and expanded uncertainty. Genetic information may be explicitly uncertain, as in the case of a variant of unknown significance (VUS). But it is also frequently uncertain whether/how the information relates to a patient's phenotype or what it may mean for a child's future. Even without ambiguity in the diagnosis or prognosis, the significance …

Seroprevalence And Risk Determinants Of Toxoplasma Gondii Infection In Pregnant Women In Pakistan: A Cross-Sectional Study, Tajul Haram, Kamran Khan

Journal of Bioresource Management

Toxoplasma gondii is a globally important zoonotic parasite, and maternal infection during pregnancy may cause miscarriage, congenital anomalies, or severe neonatal complications. This cross-sectional study was conducted among 367 pregnant women attending hospitals in District Dir Upper, Khyber Pakhtunkhwa, Pakistan, to evaluate the seroprevalence of T. gondii and associated risk factors. Blood samples were analyzed using Immunochromatographic Test (ICT) for initial screening, and positive cases were confirmed by Enzyme-Linked Immunosorbent Assay (ELISA). Overall, 34.6 % (127/367) of women tested positive. While no significant differences were observed across age groups, gestational trimesters, or abortion history, higher prevalence was noted in women …

Isolation And Molecular Characterization Of Shiga Toxin Producing Genes Stx1and Stx2 From The Captive Migratory Birds Of Lahore, Romana Zulfiqar, Hamid Ullah, Bushra Nisar Khan, Muhammad Habib Ur Rehman, Hoor Ul Ain, Alishba Zaheer, Samrah Hussain, Aazba Naeem

Journal of Bioresource Management

A total of 240 cloacal and fecal swabs were collected from 25 avian species, including ducks, swans, geese, pheasants, guinea fowl, parrots, cranes, and crows. Samples were cultured on Sorbitol MacConkey Agar, and presumptive Escherichia coli isolates were confirmed using morphological, biochemical, and molecular methods. Shiga toxin–producing E. coli (STEC) was identified through PCR detection of stx1 and stx2 genes, followed by sequencing. Antibiotic susceptibility testing was performed using the Kirby–Bauer disc diffusion method against streptomycin, ceftriaxone, ciprofloxacin, azithromycin, and tetracycline. Only four STEC isolates were recovered, resulting in an overall prevalence of 1.66 % (4/240). Positive cases were detected …

Teach-Back Techniques In Telehealth: A Review And Insights For Future Directions, Faith A. Albertson, Waka Alnakhi, Shanikque Barksdale, Shannon Stark Taylor, Shaniece Criss, Daniela B. Friedman Ph.D., Karen A. Kemper, Lorie Donelle Phd, Rn, Fcan, Wanda Thompson, Phyllis Macgilvray, Nabil Natafgi

Publications

Background and objectives: The rapid expansion of telehealth during the COVID-19 pandemic has created new challenges in patient-provider communication due to the absence of in-person interactions and visual cues. Teach-back, a method where patients repeat information to confirm understanding, is a promising tool for improving communication in virtual care. This review evaluates the effectiveness of teach-back techniques in telehealth settings.

Methods: A search of four databases (CINAHL, EMBASE, PsycINFO, PubMed) was conducted, yielding 10 studies that met the inclusion criteria. The article inclusion/exclusion criteria consisted of the following: (1) telehealth services topic; (2) direction provision related to teach-back; and (3) …

A Social Media-Based Framework For Marketing Architectural Design Firms In Egypt During Global Economic Downturn, Ayman Ahmed Ezzat Othman, Yara Ahmed Maarek

Architectural Engineering

Purpose – The global economic downturn has greatly impacted the construction industry and architectural design firms (ADFs). Social media, however, provides a strategic avenue to enhance the visibility and resilience of ADFs. This paper aims to develop a framework integrating social media as an innovative marketing approach for mitigating the impacts of the global economic downturn on ADFs in Egypt.

Design/methodology/approach – A qualitative and quantitative research approach was designed to accomplish four objectives. The literature review examined the global economic downturn and marketing ADFs. Three case studies investigated the role of social media in marketing ADFs during economic uncertainties. …

Yorkville Plaza Assoc. Llc V. Guo

All Decisions

In this Good Cause Eviction Law (GCEL) holdover proceeding, the landlord sought to non-renew the tenant's month-to-month tenancy due to alleged nonpayment of rent under Real Property Law § 216(a)(i). The tenant moved to dismiss, arguing the absence of a formal lease and pleading defects. The landlord cross-moved to amend the petition. The court denied the tenant's motion, holding that RPL § 216(a)(i) does not mandate a formal rental agreement for non-renewal based on nonpayment, unlike summary nonpayment proceedings. The landlord's cross-motion to amend was granted. The court further clarified that "rent due and owing" under GCEL requires proof of …

Cover Vol. 53 Issue 4, ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาฯ

Journal of Education Studies

No abstract provided.

Development Of A Social Media Political Engagement Scale For Thai Youth, Thanaphol Huayhongtong, Nhabhat Chaimongkol

Journal of Education Studies

The purpose of this research was to develop and validate a social media political engagement scale for Thai youth. The sample consists of 934 grade 10-12 students in the academic year 2025, from schools administered under the Office of the Basic Education Commission (OBEC), Ministry of Education. Recruiting by using a muti-stage random sampling. The research instrument was a social media political engagement scale, a 5-point Likert scale, consisting of 73 items. The psychometric quality of the scale was evaluated using the content validity index (CVI), item discrimination indices, and internal consistency reliability. The finalized scale comprised 49 items across …

Read Well, Read Right: Developing Thai Reading Skills Of Third-Grade Students Through Phonics-Based Instruction Combined With Reading Skill Exercises, Wirachai Longkaeo, Sitah Thayati

Journal of Education Studies

This pre-experimental research aimed to 1) examine the effects of phonics-based instruction combined with reading skill exercises on Thai reading skills of third-grade students, and 2) investigate the learning process and factors contributing to the success of this instructional approach. A one-group pretest-posttest was employed. The target group consisted of 15 third-grade students from a private school in Chiang Mai Province, selected through purposive sampling based on their Thai reading assessment scores, identifying students with beginning-level reading foundations. The intervention lasted 10 hours. Research instruments included 1) a Thai reading skill test, and 2) observation and student reflection form. Quantitative …

Psychological Responses To Interval And Continuous Exercise In People Living With Hiv: A Single-Blind, Counterbalanced, Crossover Study., Phelipe Wilde, Victor S. De Queiros, Jason R. Jaggers, Angelo Sabag, Julio M. Alves, Elaine Fernandes, Robert F.C. Rocha, Paulo F. De Almeida-Neto, Ronaldo Vagner Thomatieli-Santos, Paulo Moreira Silva Dantas

Faculty and Staff Scholarship

Abstract
Aim: This study compared acute psychological responses to a single session of low-volume high-intensity interval exercise (HIIE-LV), high-volume highintensity interval exercise (HIIE-HV), and moderate-intensity continuous exercise (MICE) in people living with HIV, and healthy controls using a randomized, counterbalanced crossover design. Methods: The participants (people living with HIV, and healthy controls) completed three exercise sessions in randomized order: HIIE-HV (4  4 min at 80% of maximal power output [Wmax]), HIIE-LV (10  60 s at 90% Wmax), and MICE (30 min at 60% Wmax). Psychological outcomes included affective response assessed by the Feeling Scale, exercise enjoyment and future exercise intention …

Development Of A Competency-Based Curriculum Through Co-Creation Mechanism To Build High-Skilled Labor Force: Case Studies Of Thailand, Singapore, Germany And South Korea, Panisa Harnpathananun, Somboon Sirisunhirun

Journal of Education Studies

Thailand’s time-based education system still faces limitations in developing 21st Century skills and misalignment with labor market demands. This article analyzes the development of a competency-based curriculum (CBC) through case studies of Thailand, Singapore, Germany, and South Korea, aiming to propose guidelines for enhancing high-skilled labor that corresponds to the needs of the industrial sectors. The study reveals that Thailand has CBC pilot projects such as Work-integrated Learning (WiL), Skill-Mapping, and Higher Education Sandbox. However, it also has key weaknesses, for example, weak tripartite cooperation (government, private sectors, educational institutions), insufficient financial support, inflexible curricula that do not focus on …

Development Of A Learning Activity Package With Integrated Reading Strategies To Promote Reading Literacy Among Lower Secondary School Students, Tasanee Satthaphong, Thassanant Unnanantn

Journal of Education Studies

The objectives of this study were to: 1) develop learning activity packages incorporating integrated reading strategies among lower secondary school students, with a targeted efficiency of 80/80, and 2) examine differences in students’ reading literacy performance before and after the implementation of the learning activity packages. The sample comprised 30 grade 9 students, through multi-stage random sampling, who were enrolled in the first semester of the 2024 academic year at a public secondary school in Bangkok. The intervention was conducted over a period of eight weeks, encompassing a total of 16 instructional periods. The research instruments consisted of 1) four …

Digital Resistance Against The Lasting Manipulation Of Capitalism: Ai, Luddite Rebellion, And The Haunted Future Of Cyberpunk, James Sweeting

School of Art, Design and Architecture

This paper examines the complex relationship between artificial intelligence, labour, and resistance amidst contemporary capitalism. Big Tech presents AI as revolutionary innovation, yet this narrative obscures its function in maintaining growth and preventing alternative economic forms from emerging. Through the lens of "enshittification," we observe a strategic shift toward AI deployment despite its beta state of development, threatening workers' livelihoods. This tension echoes historical patterns of technological implementation and resistance, exemplified by the Luddite movement whose meaning elites have successfully corrupted over time. The Luddites, organised under the mythical figurehead Ned Ludd (a Robin Hood-esque figure), recognised technological change as …

Detection Of The Linac Jaw Face Angle Misalignment Using High Energy Electron Beam Symmetry, Song Gao, Andres Cibrian, Jared Ohrt, Peter Balter

Faculty, Staff and Student Publications

Purpose: To demonstrate the usage of a high energy electron beam symmetry measured at different collimator angles to detect jaws face angle misalignments on Varian TrueBeam linear accelerators (linac) during acceptance and commissioning processes.

Methods: During the linac acceptance, all beams were steered to a symmetric shape with the gantry and collimator at 0°. We noted that the symmetries of higher energies electrons (e.g., 16 MeV, 20 MeV) changed over 2% when measured with the collimator at 90° and/or 270° for two linacs commissioned within 5-months of each other. Misaligned applicators were ruled out as the cause of this issue. …

Anti-Saccade Error Rates Are Associated With Somatic Depressive Symptoms In Cocaine Use Disorder, Constanza De Dios, Heather E Webber, Margaret C Wardle, Jin H Yoon, Michelle A Patriquin, Jessica N Vincent, Joy M Schmitz, Scott D Lane

Faculty, Staff and Student Publications

Background: Inhibitory control deficits are associated with cocaine use disorder (CUD) development and maintenance. Additionally, drug use and inhibitory control can be negatively affected by depressive symptoms, including somatic factors like sleep disturbance and fatigue.

Aim: The current study assessed the relationship between inhibitory control and depressive symptoms among individuals initiating CUD treatment. We examined associations among anti-saccade response inhibition performance, total scores on the Beck Depression Inventory-II (BDI-II), and individual BDI-II items.

Methods: N = 101 patients enrolled in a clinical trial for CUD completed drug-specific anti-saccade and depression (BDI-II) measures prior to treatment. Generalized linear models tested the …

Hybrid Pre-Trained Models With Machine Learning Classifier For Skin Cancer Classification, Toqa A. Sadoon, Asaad F. Qasim, Mohammed Khalaf, Ali M. Hasan

Baghdad Science Journal

Classification of skin lesions can be challenging because of the subtle variation on the skin surface due to the appearance of these lesions. In the other hand, the digital dermoscopy has been widely used by dermatologist to diagnose cancer. For accurate detection, the clinicians should have a lot of experiences, but human nature is prone to error, forgetfulness, tension, and speed in diagnosis, all of which can affect the accuracy of detection. For these reasons, automated skin lesion classification has been used by many researchers to help dermatologists in making the right and accurate decision during diagnosis. A preprocessing image …

Exploring The Therapeutic Potential Of Fermented Apple Juice And Sidr Leaves Powder On Gut Microbiota Modulation And Neuropathy Relief In Diabetic Rats, Bakenam Ali Mohamed, Alyae M.S. Gabal, Gehan M. Morsy

Baghdad Science Journal

Diabetes and its complications, particularly diabetic neuropathy, represent major health risks. This study investigated the potential of natural nutrients and bioactive compounds specifically fresh and fermented apple juice and sidr leaf powder to improve gut microbiota and alleviate neuropathy in diabetic rats. Seventy adult male Sprague–Dawley rats (180 ± 20 g) were assigned to six groups (11 rats each), while the diabetic control group (15 rats). Diabetes was induced by feeding a high-sucrose, high-fat (HSHF) diet and administering streptozotocin (45 mg/kg, intraperitoneally) during the 4^th week. The groups included: healthy control; diabetic control; diabetic rats receiving fresh or fermented …

Comprehensive Study For Characterization Of Blending And Heat Treatment Of Organic-Based Polymer Thin Films, Ruaa M. Ali, Atyaf H. Kazem, Khalidah G. Hasan

Baghdad Science Journal

Thin films of Polypyrrole (PPy)/Cupper Phthalocyanine (CuPc) have been prepared by the spin coating technique on glass substrates, Samples were prepared in a blending ratio (50:50) in addition to pure PPy and CuPc at room temperature, these samples were annealed at (473K) and then characterized by X ray diffraction (XRD), Energy Dispersive Spectroscopy (EDX) and Scanning electron microscopy (FESEM) at different magnifications power. XRD patterns reveal that pure polypyr role is amorphous. A wide peak was seen at roughly 2θ= 24° with an average crystallite size of roughly 56 nm and CuPc had a polycrystalline structure. Annealing results …

Using Physics-Informed Neural Networks For Solving 2Nd-Order Volterra Integro-Differential Equation By Deepxde Library, Oday Ahmed Jasim, Abdulghafor M. Al-Rozbayani

Baghdad Science Journal

Many disciplines widely use deep learning (DL) as a key tool for investigating the behavior of various systems. Deep learning (DL) has recently been utilized to solve differential equations using physics-based input. Physics-informed neural networks (PINNs) are a novel DL model that excels at solving both inverse and forward non-linear PDE problems. PINNs may be trained as surrogate models for approximation solutions to the VIDE without label data by embedding the physical information outlined by PDEs in feedforward NNs. The objective of this study is to solve the second-order Volterra integral-differential equations (2nd-order VIDEs) for the first time using PINN …

The Dynamic Among The Producer, Consumer, And Predator In The Presence Of Fear, Hunting Cooperation, And Anti-Predator Behavior, Muslim Saad Jabbar, Raid Kamel Naji

Baghdad Science Journal

In general, the dynamic interactions that form the relationships between predators and prey within a food chain depend heavily on fear, hunting cooperation, and anti-predator defenses. These elements support species’ survival in their particular habitats, balance the ecosystem, and control the numbers of predators and prey. Therefore, a three-species food chain system consisting of producer-consumer-predator, which plays a crucial role in ecological dynamics, has been formulated mathematically. The objective is to investigate the influence of fear, hunting cooperation, and anti-predators on the dynamic behavior of the food chain system. Two types of functional responses have been utilized. The characteristics of …

How Youth Think About Structural, Individual, And Random Sources Of Wealth Inequality, Amanda R. Burkholder, Riley N. Sims, Melanie Killen

Open Access Fund Publications

This study investigated how youth evaluate wealth inequalities, and whether youth differentiate structural, individual, and random explanations for why such inequalities exist. Understanding these distinctions is necessary for addressing exclusionary attitudes, biases, and discriminatory behaviors that emerge in childhood which have deleterious outcomes for youth. The present study included 262 youth (56.1% female; 27% Black, 49% White, 6.5% Asian American or Pacific Islander, 6% Latine, 6% multiracial, 6% other) who were 9 to 14-years-old, living in the Mid-Atlantic region of the U.S., and from primarily middle to high-middle income backgrounds. Participants evaluated wealth inequalities of different causes, reasoned about their …

Jupiter Mass Binary Objects Show A Minimum Acceleration, Mike Mcculloch

School of Engineering, Computing and Mathematics

Forty-two Jupiter Mass Binary Objects (JuMBOs) have been discovered in the Trapezium Cluster: either brown dwarf stars or planets mutually orbiting in pairs. Here it is shown that, just as in galaxies and wide binaries, the mutual orbits of the objects in each of these twin systems deviate from the Newtonian and level off around a mutual acceleration of 2��2/Θ=2×10−10 m/s2 supporting the minimum acceleration predicted by Quantised Inertia (QI), a theory that attributes inertial mass to an interaction between information horizons and quantum fields and predicts galaxy rotation without the need for dark matter. QI further predicts that the …

Volumetric Video With Skateboarders: Creative Opportunities Of Working With An Emerging Screen Technology Beyond The Studio, Dani Landau, Diego Zamora

School of Art, Design and Architecture

Volumetric video is an emerging moving image technology in which each pixel is recorded witha location in three dimensions. Volumetric videos are normally created in studios using rigs made upof multiple cameras with LiDAR sensors and computers that combine the moving images. We tookthis technology out of the studio to explore variations of this technique in public skateparks. We foundthat as the technology is still in developing stages there are creative constraints: the lidar cameras sense at a limited distance to the subject, the image is of a relatively low resolution, and there are often glitches in theimage. In our …

Visualizing The Effect Of Process Pause On Virus Entrapment During Constant Flux Virus Filtration, Wenbo Xu, Xianghong Qian, Hironobu Shirataki, Daniel Straus, Sumith Ranil Wickramasinghe

Biomedical Engineering Faculty Publications and Presentations

Virus filtration is an essential unit operation used to validate clearance of adventitious virus during the manufacture of biopharmaceutical products such as monoclonal antibodies. Obtaining at least a 10,000-fold reduction in virus particles in the permeate is challenging as monoclonal antibodies are about half the size of the virus particles. Minute virus of mice, FDA-recommended model adventitious virus, was labeled with a fluorescent dye. Laser scanning confocal microscopy was used to determine the location of virus entrapment within the virus filtration membrane. Three different hollow fiber membranes made of regenerated cellulose and polyvinylidene fluoride were tested. Feed streams consisted of …

Hospital–Medicare Advantage Vertical Integration And Cardiopulmonary Care In Integrated Hospitals, Geronimo Bejarano, Meehir N. Dixit, Alexander P. Philips, Karen E. Joynt Maddox, Meredith B. Rosenthal, Amal Trivedi, David J. Meyers

2020-Current year OA Pubs

No abstract provided.

Distinct Populations Of Lung Capillary Endothelial Cells And Their Functional Significance, Joel James, Dan Yi, Zhiyu Dai, Et Al.

2020-Current year OA Pubs

The role of the lung's microcirculation and capillary endothelial cells in normal physiology and the pathobiology of pulmonary diseases is obviously vital. The recent discovery of molecularly distinct aerocytes and general capillary (gCaps) endothelial cells by single-cell transcriptomics (scRNAseq) advanced the field in understanding microcirculatory milieu and cellular communications. However, increasing evidence from different groups indicated the possibility of a more heterogeneous nature of lung capillaries. Therefore, we investigated enriched lung endothelial cells by scRNAseq and identified five novel populations of gCaps with distinct molecular signatures and roles. Our analysis suggests that two major populations of gCaps that express Scn7a(Na

Allfromair™ Ires (Gen 3) – System Architecture, Process Physics & Compliance Verification, Vesa Olavi Lius

Defensive Publications Series

This disclosure describes the ALLFROMAIR™ IRES (Gen 3), a unified thermodynamic platform integrating heating, cooling, ventilation, and atmospheric water generation (AWG) into a single hardware unit. The system utilizes an ”Anticubic” U-channel geometry with airflow velocities <2.5 m/s to minimize fan power according to the Cube Law. Key innovations include a ”Three-Stage Rocket” thermodynamic process and a ”Turbo Effect” where regenerative pre-cooling reduces compressor temperature lift (\Delta T \approx 5K), enabling practical COPs >30.

The disclosure specifically details a pressure-modulated spray nozzle matrix capable of switching between ”Flash Evaporation” (<300 µm droplets) and ”Film Wetting” modes to maximize latent heat transfer on Heresite P-413/Hydrophilic coated exchangers. The system solves historical displacement ventilation stratification (”The Bahco Problem”) via a scavenger heat exchanger (HX4) coupled to a hydronic floor loop. An integrated ”Water Ring” harvests and purifies condensate to EU Directive 2020/2184 standards, enabling decentralized potable water production for residential, commercial, and tropical applications.

Keywords:

Integrated Regenerative Energy System (IRES), ALLFROMAIR, Anticubic U-Channel, Low Lift Heat Pump, Atmospheric Water Generator (AWG), Pressure Modulated Spray Matrix, Flash Evaporation, Thermodynamic Up-Gearing, Heresite P-413, Hydrophilic Topcoat, Radiant-Assisted Displacement Ventilation, Twin-Leg Air Separation, EU Directive 2020/2184, Three-Stage Rocket Process.

Power-Efficient Speech Detection And Transcription Utilizing Cascaded Visual Triggers And Sensor Fusion, Jon Hurwitz, Yaaseen Mahomed

Defensive Publications Series

Voice interaction is often the primary input modality for wearable electronic devices, such as augmented reality (AR) glasses. However, effective interaction via a voice interface can be difficult in certain common scenarios such as noisy environments, quiet environments where the wearer cannot provide audible spoken input, etc. This disclosure describes techniques that enable adaptive, multi-modal speech-to-text transcription on smart glasses using sensor fusion. The smart glasses include microphones (e.g., a microphone array), a vibration sensor (e.g., in the nose bridge), and low-power cameras that have the wearer’s lips in the field of view. Data streams from these sensors are combined …