Digital Commons Network^™

Imlunestrant, An Oral Selective Estrogen Receptor Degrader, In Combination With Her2 Directed Therapy, With Or Without Abemaciclib, In Er-Positive, Her2-Positive Advanced Breast Cancer: Results From The Phase 1a/1b Ember Study, Manali Bhave, Cynthia X Ma, Et Al.

2020-Current year OA Pubs

BACKGROUND: Hormone receptor-positive (HR+), human epithelial growth factor receptor 2 (HER2) overexpressed breast cancer (BC) represents the more aggressive subtype of HR + BC, typically associated with poor clinical outcomes. Despite significant advancements in the treatment of estrogen receptor-positive (ER+)/HER2 + BC, resistance to endocrine therapy (ET) poses a continued challenge. Imlunestrant is a next-generation, oral, brain-penetrant, pure antagonistic ER degrader designed to deliver continuous ER target inhibition. It has shown favorable clinical benefit, safety, and pharmacokinetics (PK) when used as monotherapy or with targeted therapy in patients with ER+/HER2- advanced BC (ABC). Here, we present the safety and efficacy …

At A Crossroads: Is English-Only Gaining New Ground In U.S. Education Policy?, Joao Goebel

SPACE: Student Perspectives About Civic Engagement

This article explores the implications of the recent Executive Order declaring English the official language of the United States, situating it within the historical context of English-only ideology and its impact on multilingual learners. While framed as a unifying policy, the order revokes Executive Order 13166, reducing federal protections for language access and echoing past efforts to marginalize non-English languages in schools. Drawing on precedents from 19th-century monolingual policies to Proposition 227, the article argues the order signals a renewed shift toward restrictive, subtractive approaches, offering an "educated guess" about their potential return and consequences. The analysis considers broader impacts …

Editorial, Todd A. Price Dr.

SPACE: Student Perspectives About Civic Engagement

No abstract provided.

Plowing With A Pencil: Policy Approaches For States Squaring Agricultural Interests With Select Public Interests, Mary Eichenberger

Journal of Food Law & Policy

From a fifth-generation wheat farmer on the Kansas plains to a cattle rancher in Montana to a beginning peach producer in Georgia, American agriculture produces, provides, and protects sources of food, fiber, fuel, and shelter. American agriculture, once solely supported by rural family farmers and steeped in an agrarian system, now relies heavily on industrialized operations, creating an arena ripe for the clash of diverse policy perspectives. As farmers produce the food enjoyed at dinner tables across the country, the inevitable impacts of agriculture production on the environment have led to policy and legal arguments surrounding the regulation of agriculture. …

Key Contributions To Agricultural Law Select Works By Agricultural Law Professor, Susan A. Schneider, An Annotated Bibliography, Susan A. Schneider

Journal of Food Law & Policy

The authors provide an annotated list of publications, remarks, books, and book chapters authored by agricultural law scholar and professor, Susan A. Schneider, in honor of her forthcoming retirement.

The growth and evolution of the study of agricultural and food law may be attributed to several legal scholars who, based on a personal connection with agriculture, chose to dedicate their careers to advocating for the family farmer. Professor Susan A. Schneider is one such legal scholar.

Professor Susan A. Schneider, a native of Minnesota, is currently the William H. Enfield Professor of Law and the Director of the LL.M. in …

P-E-S-T-O-G-O: This Third Circuit Ruling Has Got To Go, A Deep Dive Into The Circuit Split Issue Of Fifra Preemption, R. Dylan Smith

Journal of Food Law & Policy

The American public is becoming increasingly concerned about pesticides. From “forever chemicals” to environmental justice concerns, public awareness of pesticide issues is only becoming more prevalent. However, one pesticide has seized public attention in a significant way. Glyphosate, the active ingredient in Monsanto’s “Roundup” and other commercial pesticides has been the subject of heated debate in federal courtrooms across the nation. The rising controversy over glyphosate has even led some jurisdictions to attempt to ban or restrict the use of the product altogether.

While the scientific studies and legal definitions about glyphosate and its cancer link are inconsistent, a reasonable …

An Interview With Former United States Department Of Agriculture General Counsel Janie Simms Hipp And Former Farm Credit Administration General Counsel David Grahn: Reflections On The Past & Future Of The Field Of Agricultural Law, Lauren Wustenberg

Journal of Food Law & Policy

Former United States (“U.S.”) Department of Agriculture (“USDA” or “Department”) General Counsel Janie Simms Hipp and Former Farm Credit Administration (“FCA”) General Counsel David Grahn have worked as public servants in the field of agricultural law for over forty years. They have led careers that are illustrative of the meaningful impact that a career in agriculture can have, the breadth and value of the Department of Agriculture, and the diversity of experiences and opportunities that a career in agricultural law can bring.

Janie and David graciously agreed to sit for the following interview in recognition of the 20th Anniversary Edition …

Municipalities, Let The People Have Their Chickens And Eat Them, Too, Cindy Vong

Journal of Food Law & Policy

In the pre-industrial era, before the advent of long-distance transportation or food preservation, human survival necessitated proximity to where food was grown or husbanded. Cities located near agriculturally productive lands and domesticated livestock animals were commonplace within cities. But by the 1920s, the technological innovations of the Second Industrial Revolution left urban areas free of farm animals and farm-related activities. Local governments exercised their powers to codify the separation of residential and agricultural uses within cities and reinforce the idea that food production was not proper in community neighborhoods. Yet, a century later, local governments use those same powers to …

Why Food In The United States May (Still) Never Be Safe: A Look Back At My Over Thirty Years Thinking About Food And The Law, Denis Stearns

Journal of Food Law & Policy

This article can serve a function as a concluding section—a kind of coda—for issues addressed in greater depth by the author (Denis Stearns) before.

This article also allows Sterns to return to a central question that prompted his thought-journey in the first place: Why does the food in this country continue to be so unsafe, despite all of the laws, all of the enforcement efforts, all of the food safety advocacy, and all of the lawsuits filed to recover damages on behalf of people injured and killed year after year. What follows, then, are additional and updated conclusions that thirty …

The Law Of Hard Times: What Today’S Lawyers And Policymakers Can Learn From The Farm Crisis Of The 1980s, Sarah Vogel, Mary Eichenberger

Journal of Food Law & Policy

It is undeniable, the United States is experiencing another farm depression similar to the Great Depression of the 1930s and the Farm Crisis of the 1980s. While every era is different, knowledge of the case law developed during the farm struggles of the 1930s and 1980s, and the statutory and regulatory reforms that arose from advocacy during those difficult times will be helpful to today’s agricultural lawyers and policymakers. As farmers and ranchers again find themselves, due to circumstances beyond their control, in financial distress, they will contact attorneys, state secretaries of agriculture, state attorneys general, agriculture organizations, and state …

Reflection And Gratitude: The Journal Of Food Law & Policy From A Twenty-Year Perspective, Margie Alsbrook

Journal of Food Law & Policy

Twenty years after the Journal of Food Law & Policy published its first issue, I find myself looking back with deep gratitude for the people who helped create it, for the students who sustained it, and for the community that continues to make it thrive. What began as an untested idea has grown into a respected publication and a cornerstone of a still-growing field. This essay is both a reflection on that journey and a heartfelt thank-you to everyone who made it possible.

Contents, Journal Editors

Journal of Food Law & Policy

No abstract provided.

Journal Of Food Law & Policy -Fall 2025, Journal Editors

Journal of Food Law & Policy

No abstract provided.

Exploring Trends, Key Themes And Research Dimensions Of Banks And E-Commerce Research, Akshay Kumar Mishra, Srikant Gupta

Management Dynamics

Purpose - The purpose of this study is to present a bibliographic evaluation and literature review in order to identify publications, important themes, and trends in the area of banks and e-commerce.

Design/Methodology - The present study employed a bibliometric analysis of scholarly articles pertaining to the selected research domain. The relevant publication data was obtained from the Scopus database by using appropriate search terms. The bibliometric methodology is employed to discern patterns, significant contributions, and prospective research avenues by utilizing bibliometric indicators, including publication count, citation count, network analysis, and thematic analysis.

Finding - The analysis has identified several …

Effectiveness Of Cleansing Methods On Saliva Contaminated Zirconia: A Comparative Study Using Energy Dispersive X-Ray Spectroscopy And Scanning Electron Microscopy, Reyam Zahir Alsultani, Mohammed Kassim Gholam

Maaen Journal for Medical Sciences

Aim of the study: The study aimed to evaluate and compare the effectiveness of various decontamination protocols in removing contamination of saliva from the surface of zirconia and enhancing their cleanliness to enhance optimal bonding. Material and Method: Fifty-six multilayer (ML) monolithic high translucent zirconia discs (DD cubeX2 ® ML;10 mm × 2 mm) were fabricated through milling and sintered in according to the manufacturer's guidelines. The specimens were then air-abraded with 50 µm aluminium oxide particles after being polished with silicon carbide abrasive paper. The samples were randomly assigned to 5 groups (n = 10) based on the cleaning …

Chaos Engineering In Multi-Gigahertz Solid-State Lasers: A Novel Approach To Optoelectronic Control, Mikhail V. Gorbunkov, Yulia Ya. Maslova, Yulia A. Sinichkina

Karbala International Journal of Modern Science

This paper presents a comprehensive study of a multi-gigahertz chaotic generator of light pulses based on solid-state laser sources, including fiber lasers, governed by carefully designed positive and negative feedback loops. It harnesses the inherent nonlinear dynamics within a solid-state laser controlled by a combination of two inertial feedback loops, enabling the realization of complex chaotic behavior, including the logistic map scenario, under moderate amplification conditions. The laser system dynamics are rigorously investigated through theoretical modeling, employing a nonlinear map approach, and high-resolution picosecond simulations. The results of our numerical simulations highlight the efficacy of fast electro-optical feedback system with …

Unveiling The Anticancer Potential Of Syzygium Cumini: In Silico Insights Into Its Mechanistic Action Against Non-Small Cell Lung Cancer, Nur Sofiatul Aini, Win Darmanto

Karbala International Journal of Modern Science

Non-small cell lung carcinoma (NSCLC) is the most periodic type of lung cancer and the second most diagnosed cancer globally. Syzygium cumini is plant that extensively used in cuisine and traditional medicine. However, its potential for NSCLC treatment has not yet been elucidated. This study determined the potential of S. cumini as anti-NSCLC using in silico approaches. The in silico study was applied to perform active compound analysis, selection of target candidates, network pharmacology, functional annotation, molecular docking, and molecular dynamics simulation, respectively. Based on open source databases, S. cumini contained 115 compounds and 14 of them predicted to have …

We Built This: Redesigning Higher Education From The Ground Up While They Try To Burn It Down, Shawntay King, Juanita E. Marquez, Keisha Rembert, Jolene Taylor, Thera Tilmon

SPACE: Student Perspectives About Civic Engagement

Our text, We Built This: Redesigning Higher Education from the Ground Up While They Try to Burn It Down, examines how recent federal policy shifts, particularly the 2025 Dear Colleague letter and the Project 2025 educational platform, function as deliberate acts of deconstruction. These measures threaten to dismantle equity infrastructures in higher education while intensifying the erasure of Black women’s labor, leadership and legacy in the academy. Through Critical Policy Analysis and Black feminist thought, we argue that these policies operate simultaneously as blueprint and wrecking ball, systematically unraveling decades of progress and constraining the very communities that have sustained …

Making A Martyr: The Inequity Of The Necessity Doctrine’S Application To The Fifth Amendment’S Takings Clause, Max Abrams

Villanova Law Review (1956 - )

No abstract provided.

Cv: Catherine Bohlin (Exercise Science), Catherine Bohlin

Health Sciences Department Curricula Vitae

No abstract provided.

The Other Side Of Rousseau’S Political Theology: The Influence Of Plutarch And Calvin On The Profession Of Faith Of The Savoyard Vicar, Thomas Daniel Moore

Yale Divinity School Theses

This thesis examines Jean-Jacques Rousseau’s Profession of Faith of the Savoyard Vicar, paying particular attention philosophic influences of the Vicar, especially as pertains to metaphysics. It fills a void in the scholarship, as there is not much work in general–and especially in recent years–on the relationship between Plutarch, Calvin, and Rousseau. Indeed, although Rousseau’s love for Plutarch is often acknowledged, it is seldom explored; and, when it is explored, it is typically only with an eye to the political realm, and never the metaphysical dimension. Calvin, when mentioned in association with Rousseau at all, is typically interpreted as a minor …

Commencement [Program], December 20, 2025, University Of Northern Iowa

UNI Commencement Programs

Contents:

University Organization --- 2
Ceremony Symbols & Traditions --- 3
University Honors Program --- 4
Graduation with Honors --- 4
Legacy Graduates --- 4
Order of Events --- 5
College of Education --- 6
College of Humanities, Arts & Sciences --- 12
College of Social & Behavioral Sciences --- 19
David W. Wilson College of Business --- 26
Division of Online Education & Individual Studies --- 31
UNI Alma Mater --- 34

Impact Of Community Health Needs Assessments As Barriers To Chronic Disease Prevention: A Comparative Study, Marissa E. Woelm Ms.

Honors Thesis

Community health needs assessments (CHNAs) are vital tools for identifying population health priorities through monitoring chronic diseases and conditions; however, their effectiveness in preventing chronic diseases remains debated. This comparative study examines CHNAs from sixteen South Dakota hospitals across Avera, Sanford, Monument Health, and independent systems to evaluate their role in preventing chronic diseases. Analysis reveals significant challenges, including biased data sampling, limited community engagement, small survey samples, and inconsistent implementation strategies. While CHNAs effectively identify mental health, cancer, and obesity as the top community concerns alongside several other diseases like diabetes and kidney disease, most reports lack specific timelines …

Optimization Of Actuator Stiffness And Actuation Timing Of A Passive Ankle Exoskeleton: A Case Study Using A Musculoskeletal Modeling Approach, Jania Williams, Cody P. Anderson, Arash Mohammadzadeh Gonabad, Farahnaz Fallahtafti, Sara A. Myers, Hafizur Rahman

School of Podiatric Medicine Publications

Objective: A modeling and simulation tool, OpenSim, was used to determine the optimal relationship between actuator stiffness and actuation timing of a passive ankle exoskeleton for reducing metabolic costs during walking. We hypothesized that the absolute minimum in total metabolic cost would exist at an actuation timing of 15% of stance and at a spring stiffness of 7.5 kN/m. We also hypothesized that a local minimum in total metabolic cost would exist at an actuation timing of 50% of stance. Methods: Bilateral kinematics and kinetics data were collected on a healthy male walking overground wearing his regular tennis shoe. The …

Building Relationships: Does Perceived Counselor Cultural Humility Improve Client Satisfaction Of Mental Health Services Within Therapeutic Dyads Of Dissimilar Identities?, Noah Schoch

Electronic Theses and Dissertations

A wealth of clinical research has uncovered the presence of mental health treatment disparities and a lack of treatment consistency when working with clients of dissimilar identities. The purpose of this dissertation study was to investigate potential causes for the observed disparities minoritized individuals have experienced and understand if cultural humility was a variable that affected mental health treatment satisfaction when counselor-client had dissimilar cultural identities. This was achieved through the following research questions: (1) What is the relationship between the extent of client perceived racial/ethnic similarity within the therapeutic dyad and client-rated mental health treatment satisfaction? (2) What is …

Neutrosophic Communication Pathways Model: Exploring The Dissemination Of Excellent Traditional Chinese Culture In The Age Of New Media, Xueyu Liu, Tianjiao He

Neutrosophic Sets and Systems

No abstract provided.

Digital Teaching Competence Evaluation Of University Physical Education Teachers Under Neutrosophic Triplets Methodology, Yangzhong Li

Neutrosophic Sets and Systems

No abstract provided.

Implementation Of Neutrosophic Logic For Food Security And Agricultural Productivity Analysis In South Asian Countries, Muhammad Yaseen, Korntima Phattanasin, Jamil Afzal, Muhammad Afzal

Neutrosophic Sets and Systems

No abstract provided.

Integrating Traditional Diagnostics Methods Through Neutrosophic Set Based Cancer Analysis Using Machine Learning Techniques, P. Tharaniya, M. Raji, R. Rajalakshmi, Surapati Pramanik, R. Balapriya, M. Gayathri Lakshmi

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Hyperprobabilistic Modeling Of Learning Outcomes In College Blended Physical Education Teaching Process, Yanmin Li, Shiqiang Dou

Neutrosophic Sets and Systems

No abstract provided.