Digital Commons Network^™

Sample Ascertainment And Recruitment Sources In The Accelerating Medicines Partnership Schizophrenia Program, Jean Addington, Daniel Mamah, Et Al.

2020-Current year OA Pubs

BACKGROUND: This paper presents the recruitment sources of clinical high-risk (CHR) and community controls (CC) from the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) program, which aims to study various clinical variables and biomarkers in 2040 CHR and 652 CC participants.

METHODS: A total of 1640 CHR and 514 CC had recruitment source data. The Positive Symptoms and Diagnostic Criteria for the Comprehensive Assessment of At-Risk Mental States Harmonized with the SIPS was utilized to assess CHR criteria and severity of attenuated psychotic symptoms (APSs), and the Global Functioning: Social Scale was used for social functioning. Participants were recruited through various …

Baseline Clinical Characterization Of Participants In The Accelerating Medicines Partnership Schizophrenia Program, Jean Addington, Daniel Mamah, Et Al.

2020-Current year OA Pubs

BACKGROUND: This paper focuses on the baseline clinical characterization of the participants in the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) program. The AMP SCZ program is designed to investigate a wide array of clinical variables and biomarkers in a total of 2040 clinical high-risk (CHR) participants and 652 community control (CC) participants.

METHODS: The dataset analyzed includes 1642 individuals at clinical high risk for psychosis and 519 CCs. Key measures include the Positive Symptoms and Diagnostic Criteria for the Comprehensive Assessment of At-Risk Mental States Harmonized with the Structured Interview for Psychosis-Risk Syndromes, which determined CHR criteria and the severity …

Sociodemographic Factors Predict Outcomes And Reveal Spatial Tumor Patterns In Glioblastoma, Patrick H Luckett, Michael Olufawo, Noah Naddaff-Slocum, Ki Yun Park, Bidhan Lamichhane, Donna Dierker, Gabriel Trevino Verastegui, John J Lee, Peter Yang, Albert Kim, Omar H Butt, Milan G Chheda, Abraham Z Snyder, Joshua S Shimony, Eric C Leuthardt

2020-Current year OA Pubs

BACKGROUND: Glioblastoma (GBM) is the deadliest malignant glioma of the central nervous system. Postsurgical functional impairment correlates with survival and is estimated using metrics such as extent and location of resection. This study uses machine learning to evaluate the predictive ability of baseline sociodemographic and lifestyle factors for forecasting postoperative functional outcomes in GBM patients.

METHODS: Glioblastoma patients (

RESULTS: Utilizing decision trees with age, SVI/SES, sex, tobacco use, alcohol use, obesity, and race as predictors, we achieved 88% accuracy in classifying median KPS and 85% accuracy in classifying KPS slope. Socioeconomic factors were the strongest predictors. Age, sex, and …

Preliminary Investigation Of Obstructive Sleep Apnea And Alzheimer's Disease In Down Syndrome, Dasoo M Yoon, David T Plante, Victoria Fleming, Benjamin Handen, Patrick Lao, Jamie Peven, Bradley Christian, Ozioma Okonkwo, Charles Laymon, Beau Ances, Christy Hom, Brian Helsel, Sigan L Hartley

2020-Current year OA Pubs

This study provided a preliminary examination of indices of obstructive sleep apsnea (OSA) and sleep disruptions in adults with Down syndrome (DS), and their associations with Alzheimer's disease (AD) pathology and symptomatology. A total of 93 adults with DS (aged 25-61 years) from the Alzheimer Biomarker Consortium-DS completed cognitive assessments, MRI and positron emission tomography (PET) scans (assessing amyloid-beta [Aβ] and tau), and a one-night home sleep study using the WatchPAT-300 device. Study partners also reported on depressive symptoms and diagnoses. Correlational analyses examined relationships between sleep variables, PET biomarkers, and AD symptomatology (cognitive functioning and depressive mood), controlling for …

Thalamic And Visual Network Dysfunction Relates To Tremor Response In Thalamic Deep Brain Stimulation, Aimee E Morris, Babatunde Adeyemo, Meghan C Campbell, Abraham Z Snyder, Joel S Perlmutter, Jonathan W Mink, Scott A Norris

2020-Current year OA Pubs

BACKGROUND: Essential tremor (ET) is the most common movement disorder in adults, but its pathogenesis is incompletely understood. Deep brain stimulation of the ventral intermediate thalamic nucleus (VIM DBS) provides effective treatment for medically-refractory cases. We aimed to determine how pre-surgical resting-state functional connectivity (FC) in medically-refractory ET relates to VIM DBS clinical response.

METHODS: We analyzed resting-state FC MRI in 21 participants with medically-refractory ET who subsequently underwent VIM DBS and 34 matched controls. We applied rigorous quality assurance to minimize motion artifact. Whole-brain correlation matrices were computed across 300 cortical, subcortical, and cerebellar regions and compared across groups …

Proteomic Characterization And Comparison Of The Infective And Adult Life Stage Secretomes From Necator Americanus And Ancylostoma Ceylanicum, Yide Wong, Bruce A. Rosa, Makedonka Mitreva, Et Al.

2020-Current year OA Pubs

More than 470 million people globally are infected with the hookworms Ancylostoma ceylanicum and Necator americanus, resulting in an annual loss of 2.1 to 4 million disability-adjusted-life-years. Current infection management approaches are limited by modest drug efficacy, the costs associated with frequent mass drug administration campaigns, and the risk of reinfection and burgeoning drug resistance. Subunit vaccines based on proteins excreted and secreted (ES) by hookworms that reduce worm numbers and associated disease burden are a promising management strategy to overcome these limitations. However, studies on the ES proteomes of hookworms have mainly described proteins from the adult life stage …

Cancer-Targeted Pro-Theranostic Bi-Metallic Organo-Coordination Nanoparticles, Hengbo Huang, Lei Fang, Janaka Wansapura, Julie L Prior, Brad Manion, Baogang Xu, Cody Hongsermeier, Nisha Gamadia, Nicole Blasi, Rui Tang, Christopher Egbulefu, Monica Shokeen, James D Quirk, Samuel Achilefu

2020-Current year OA Pubs

No abstract provided.

Measuring Stigma In Pediatric Oncology: A Cross-Sectional Analysis Of Three Global Sites, Lara E Counts, Sara M Malone, Et Al.

2020-Current year OA Pubs

PURPOSE: Stigma contributes to fear and shame, resulting in delays in care-seeking behavior among individuals with cancer. As a social construct, stigma is affected by language, religion, culture, and local norms. This study explored pediatric cancer stigma at the time of diagnosis across diverse settings through the adaptation of two stigma measures.

METHODS: This study was conducted with adolescents and caregivers of children with osteosarcoma and retinoblastoma at three centers in Jordan, Guatemala, and Zimbabwe. The Stigma-related Social Problems (SSP) and the eight-item Stigma Scale for Chronic Illness (SSCI-8) measures were translated into Arabic, Spanish, and Shona and contextually adapted …

Abdominal Myosteatosis Measured With Computed Tomography Predicts Poor Outcomes In Patients With Glioblastoma, Farzaneh Rahmani, David H Ballard, Tammie L S Benzinger, Sonika Dahiya, John Evans, Sara Hosseinzadeh Kassani, Cyrus A Raji, Marilyn J Siegel, Joseph E Ippolito, Et Al.

2020-Current year OA Pubs

BACKGROUND: Alterations in cellular metabolism affect cancer survival and can manifest in metrics of body composition. We investigated the effects of various body composition metrics on survival in patients with glioblastoma (GBM).

METHODS: We retrospectively analyzed patients who had an abdominal and pelvic computed tomography (CT) scan performed within 1 month of diagnosis of GBM (178 participants, 102 males, 76 females, median age: 62.1 years). Volumetric body composition metrics were derived using automated CT segmentation of adipose tissue, skeletal muscle, and aortic calcification from L1 to L5. Univariable and multivariable Cox proportional hazards models were performed separately in males and …

Enhancing Engagement In Hiv Care Among Adolescents And Young Adults: A Focus On Phone-Based Navigation And Relationship Building To Address Barriers In Hiv Care, Harriet Fridah Adhiambo, Dorothy Imbuka Mangale, Elvin Geng, Et Al.

2020-Current year OA Pubs

Structural, psychological, and clinical barriers to HIV care engagement among adolescents and young adults living with HIV (AYAH) persist globally despite gains in HIV epidemic control. Phone-based peer navigation may provide critical peer support, increase delivery flexibility, and require fewer resources. Prior studies show that phone-based navigation and automated text messaging interventions improve HIV care engagement, adherence, and retention among AYAH. However, little is known about AYAH experiences utilizing electronic phone-based peer navigation and automated text messaging (E-NAV). We assessed the experiences of AYAH receiving phone-based peer navigation to address barriers to HIV care engagement and viral suppression. We purposefully …

Trauma-Informed Care In Occupational Therapy Education, Cristina H. Scionti, Mary Shotwell, Donnamarie Krause

Journal of Occupational Therapy Education

Students bring their life histories, including traumatic experiences, to their learning and education. Potentially up to 75% of the student body of occupational therapy programs may have experienced a traumatic event, which often leads to occupational disruption and challenges in academic performance. Thus, it is critical for occupational therapy educators to mitigate the impact of trauma by identifying the barriers and facilitators to occupational participation in education for occupational therapy students affected by trauma. Despite the high prevalence of adverse childhood experiences (ACEs), research shows that few health professions education programs, such as occupational therapy, attend to ACEs or utilize …

Reimagining Education For Ot And Ota Intraprofessional Collaboration: A Virtual Pilot Program, Katelyn Brady, Heather Beth Johnson, Alexandra Stellmach

Journal of Occupational Therapy Education

Intraprofessional knowledge and skills are essential to the field of occupational therapy. Despite the importance, not all occupational therapy (OT) and occupational therapy assistant (OTA) educational programs provide collaborative intraprofessional experiences to students who are expected to collaborate effectively in practice. Therefore, increased intraprofessional experiences are needed to support entry-level OT practitioners. The purpose of this project was to create an intraprofessional pilot program that included three intraprofessional events to provide an opportunity for collaboration between OT and OTA students and enhance their understanding and confidence with intraprofessional collaboration prior to practice. The pilot program was implemented and evaluated using …

Exploring Student Experiences And Perceptions Of Digital Storytelling In Occupational Therapy Education: A Comprehensive Analysis And Evaluation, Alexis M. F. Morin, Justin R. Eck

Journal of Occupational Therapy Education

The COVID-19 pandemic heightened the need for digital transformation in higher education, emphasizing the importance of incorporating digital pedagogy. This study explored student experiences and perceptions of digital storytelling, a multimedia-based narrative technique, as an innovative assessment method in occupational therapy education. First-year, first-semester entry-level Doctor of Occupational Therapy students created digital stories on mental health topics and completed self-reflection papers. A retrospective qualitative descriptive method was employed, analyzing 14 consented self-reflection papers. Emerging qualitative themes revealed that digital storytelling enhanced students' understanding of occupational performance impacts, led to the development and utilization of transferrable skills for clinical practice, and …

Improving Self-Regulated Learning Among Occupational Therapy Students, Pola Ham

Journal of Occupational Therapy Education

Many occupational therapy students, particularly first-generation students, face significant academic and social challenges in higher education that affect their self-regulated learning (SRL). SRL involves goal setting, self-monitoring, strategy implementation, and reflection. The rigorous academic demands, combined with the unique challenges experienced by many first-generation students, exacerbate these difficulties, particularly in developing SRL skills, which are essential for academic and professional success. While first-generation students often lack these skills due to a variety of factors, many occupational therapy students also struggle to develop these skills, regardless of background. This narrative review examines the role of SRL in occupational therapy education and …

The Re-Design Of Level I Fieldwork To Foster Professional Competence And Career Adaptability, Cara A. Lekovitch, Ann Marsico, Ketki Raina

Journal of Occupational Therapy Education

Professional competence and career adaptability are essential for preparing students to meet modern healthcare demands. However, there is a paucity of evidence to guide teaching and learning of these constructs in the context of Level I fieldwork (FW). This paper details a Level I FW program re-design using a professional competence framework to foster adaptability. The re-design’s impact was assessed through student surveys before and after their participation (n = 53) compared to a historical cohort one-year senior (n = 60) using the Career Adapt-Abilities Scale – Short Form. Significant improvements were found in total and concern, curiosity, and confidence …

Demographic Factors As Predictors Of Academic Performance In First- And Second-Year Occupational Therapy Students, Eileen Du Plooy, Daleen Casteleijn, Denise Franzsen, Gopika Ramkilawon

Journal of Occupational Therapy Education

Significant disparities in academic performance that may be associated with specific demographics can be utilized for supporting diverse student cohorts. Strategies can be developed for students to enhance equity and inclusivity in undergraduate occupational therapy education to ensure student success. This study aimed to determine the predictive demographic factors influencing academic performance among first- and second-year undergraduate occupational therapy students at a university in South Africa. A quantitative, cross-sectional design was utilized, and the sample included 129 first- and second-year students. Data were collected retrospectively from university records and student dashboards. Key demographic and academic variables were analyzed, including personal …

Harnessing Social Media For Occupational Therapy Graduate Program Recruitment, Rebecca Ozelie, Annika Knuth

Journal of Occupational Therapy Education

The occupational therapy (OT) profession faces a national enrollment decline, with many United States graduate programs struggling to fill seats. As social media use continues to rise among young adults, OT programs may benefit from leveraging digital platforms to enhance visibility and attract qualified applicants. This study explored how prospective students engage with OT program social media accounts and what content influences their admissions decisions. Using a cross-sectional survey design, 161 current or incoming OT graduate students from programs across the United States were surveyed about their social media habits during the admissions process. Results revealed that 69.5% of participants …

How Identities Shape Belonging In Occupational Therapy Education: A Phenomenological Exploration Of Student Belonging, Quinn P. Tyminski, Rowhea Elmesky

Journal of Occupational Therapy Education

Belonging is defined in a variety of ways but most often refers to an individual’s feelings of acceptance, inclusion, support, and respect within a certain environment. Belonging is an innate human need and contributes to success in academic and professional settings. Within occupational therapy (OT) education, minimal attention has been paid to the specific concept of belonging with no research focused on long-term qualitative explorations of student belonging for students with historically minoritized identities (HMIs). Thus, the goal of the present study was to better understand how students with multiple HMIs experienced the phenomenon of belonging in OT education. Utilizing …

Effective Implementation Of Ebook Guide Supports Student Success In Occupational Therapy Anatomy Education, Karissa Legleiter, Barb Puder, Rhea R. Kimpo

Journal of Occupational Therapy Education

EBooks have been proven to be a successful supplemental resource in cadaveric anatomy laboratory sessions. However, the implementation of the eBook and its impact on student performance, especially in occupational therapy (OT) anatomy laboratory sessions, has not been well documented. This study shows that providing students with an eBook guide enhances student learning and increases eBook usage. For lab sessions, an eBook guide directed students to eBook specific figures and text that related to that session’s material. In alignment with the Universal Design for Learning (UDL) framework, providing eBooks as well as a guide gave students multiple avenues to learn …

Naming The Invisible: Exploring Implicit Design Thinking In Occupational Therapy Curricula, Dominique C. Sherratt, Mary Butler, Shoshannah Kiriam, Ben Sellar

Journal of Occupational Therapy Education

Occupational therapy inherently involves the application of design and co-design skills within professional practice, yet there is limited evidence about how these skills are taught to students. This study used a qualitative descriptive design to explore the perspectives of occupational therapy educators in Australia and New Zealand on how and where design and co-design skills are integrated within occupational therapy curricula. Educators were purposively sampled from the Australian and New Zealand Council of Occupational Therapy Educators (ANZCOTE), with additional participants recruited through snowball sampling. Eight semi-structured interviews were conducted with occupational therapy educators. Interviews were conducted and analyzed using the …

Theory-Driven Design, Theory-Integrated Learning: A Multimodal Approach To Teaching Occupational Adaptation, Anna B. Galloway, Lorrie A. George-Paschal, Linda Struckmeyer, Sara F. Israel, Nancy Krusen

Journal of Occupational Therapy Education

This study explored the effectiveness of a multimodal instructional module for teaching Occupational Adaptation (OA) theory. Implemented across three entry-level occupational therapy doctoral (OTD) programs, faculty designed and implemented asynchronous preparatory lectures, a face-to-face experiential lab, and guided discussions of the learning experiences. Researchers employed a convergent mixed-methods design, integrating qualitative and quantitative data. Students (n=108) completed a pre- and post-knowledge exam, the Relative Mastery Scale (RMS), and a Learning Experience Questionnaire. Analysis of variance (ANOVA) revealed statistically significant differences in pre-and post- knowledge scores and RMS ratings across all sites, with no differences based on university. Qualitative analysis yielded …

Navigating The Future Of Ot Education: Student Insights On Integrating Course-Specific Ai Chatbots, Laura E. Landon, Nicole Grames, Maggie Gannon, Addison Jarus, Annie Trezza

Journal of Occupational Therapy Education

The integration of artificial intelligence (AI) in higher education has garnered much attention, prompting educators to thoughtfully examine its implementation within their curricula. This study explores the perceptions of occupational therapy (OT) students regarding the future integration of a novel, course-specific Anatomy AI chatbot: an innovative tool uniquely developed by our internal team to provi¬¬¬de personalized support and resources tailored specifically to the anatomy curriculum. The researchers sought to understand the desired features of a course-specific Anatomy AI chatbot and the factors that influenced student willingness to adopt this technology in their learning experience. Findings revealed that 79% of participants …

Reading Between The Lines: Exploring Reading Trends And Metacognitive Strategy Use In Ot Education, Whitney Henderson, Christine Davis, Christen Leach, Theresa Hallenen

Journal of Occupational Therapy Education

No abstract provided.

Assessing The Impact Of High-Fidelity Simulation Experiences On Student Confidence In A Controlled Academic Environment, Jillian K. Pindar, Peyton Belton, Madison Griffin, Abbi Hancock, Lucero Limones, Kristi Self, Elizabeth K. Schmidt

Journal of Occupational Therapy Education

A quasi-experimental one group pretest-posttest design was utilized with 19 first-and-second-year doctoral occupational therapy students at a university in Tennessee to evaluate confidence, performance, benefits, challenges, and recommendations from an acute care simulation experience. Student confidence was evaluated using a researcher-developed survey immediately before and after a high-fidelity simulation using a pre-programmed mannequin and standardized script. A performance assessment evaluated students' skills during the simulation. The post-test survey included open-ended questions on perceived benefits, challenges and recommendations. Overall, students demonstrated increased confidence in vital sign monitoring and modification (heart rate, blood pressure, respiratory rate), medical equipment identification, and safe patient …

Factors Influencing Occupational Therapy Doctorate Program Offer Acceptance Across Student Demographics, Megan Hoover, Mckenna Johnson, Colleen Bullen, Elizabeth K. Schmidt, Jackson M. Miller

Journal of Occupational Therapy Education

This research study aimed to identify key factors influencing Doctor of Occupational Therapy (OTD) students' acceptance of program offers. An online survey was developed based on relevant literature and study objectives and validated through expert review. A total of 281 students, including a sub-set of students from underrepresented backgrounds (n=70), across the United States completed the survey. Quantitative data was analyzed using descriptive statistics, cross-tabulations, Chi-square tests with Bonferroni correction, and multinomial logistic regression including demographic variables and factors moderately to strongly influencing program acceptance. Qualitative responses were analyzed using content analysis. Key findings reveal geographic location, application process, cost …

Perceptions Of Occupational Therapy Student Fieldwork Readiness In The Acute Care Setting, Jackie Dusing, Lisa Borrero, Elizabeth Horrall Stith, Kristina Watkins

Journal of Occupational Therapy Education

Occupational therapy student readiness for Level II fieldwork is necessary for preparing novice clinicians and is challenging to assess, as it requires applying didactic knowledge in real-world clinical settings. There is currently a gap in the literature regarding student perceptions of their readiness for Level II fieldwork, especially in the acute care setting. The aim of this qualitative study is to better understand Doctor of Occupational Therapy (OTD) students’ perceptions of readiness for Level II fieldwork in an acute care setting. This basic interpretive qualitative research study utilized a purposeful sampling with students completing their Level II fieldwork in various …

Comparing Occupational Therapy Students’ And Occupational Therapy Assistant Students’ Perceptions Of An Intraprofessional Class Session, Robyn Wu, Diane Tom, Domenique Embrey, Joyce M. Fries

Journal of Occupational Therapy Education

Intraprofessional education between occupational therapy (OT) and occupational therapy assistant (OTA) students can be a valuable component of the entry-level curriculum. Comparisons of OT vs. OTA students’ perceptions are sparse, yet this information may yield important insights about intraprofessional learning needs. This mixed methods study explored student perceptions of a three-hour joint OT/OTA class session conducted via video conferencing. Learning activities were grounded in shared leadership and two-way feedback and included collaboration on a client case. A total of 172 anonymous post-class feedback surveys were received from 121 OT students and 57 OTA students over three academic years. The study …

Fieldwork Supervision, Motivation And Competency Among Norwegian Community-Based Occupational Therapists, Even E. Edvardsen, Tore Bonsaksen, Sissel Horghagen, Cathrine Arntzen, Unni Sveen, Astrid Gramstad, Ruca E. K. Maass, Linda Stigen

Journal of Occupational Therapy Education

Occupational therapists’ supervision of students remains a critical component during occupational therapy education. This study aimed to examine supervision practice, motivation, and competency among community-based occupational therapists in Norway, exploring organizational and personal factors associated with formal and perceived supervision competency, willingness to serve as fieldwork educators, and collaboration with educational institutions. A cross-sectional survey was distributed among occupational therapists in community-based practice in Norway. A total of 617 occupational therapists participated in the study. Free-text responses were thematically analyzed and interpreted. Differences between fieldwork educators and non-fieldwork educators’ training, recency of being fieldwork educators, willingness to assume the role …

Women Spinning On The Edge: Finding And Redefining The “Spinster” In The Witches Of Discworld, Kathryn Ann Fitzmaurice

Masters Theses

The word “spinster” has undergone a series of evolutions over the past seven hundred years, first coined to describe the occupation of women engaged in the spinning of plant and animal fibers into thread and yarn in the Middle Ages and later a legal marital status designation used until the 21^st century. The connotation associated in social contexts became pejorative. This project’s tracing of the word spinster is used to set up the broader scope looking at how the spinster can be viewed as an archetype, what we can learn through the lenses of gender and feminist theory, and …

The Weapon Focus Effect On Memory For Male And Female Perpetrators, Faith Christel Aasen

Theses and Dissertations

Previous research on the weapon focus effect suggests that weapon presence causes reduced memory accuracy for perpetrator details due to weapons being surprising and unexpected. The unusualness hypothesis suggests that a stronger weapon focus effect should occur when the perpetrator defies typical gender stereotypes, such as a woman holding a gun. The current study sought to examine how the weapon focus effect impacts eyewitness memory for male and female perpetrators, specifically exploring the magnitude of the effect on female perpetrators. The current study further investigated whether the own gender bias attenuates the weapon focus effect on memory for female perpetrators. …