Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 9811 - 9840 of 10496

Full-Text Articles in Entire DC Network

Evidence-Based Evaluation To Promote High-Value Care In Pediatric Critical Care: It Is Time To Fully Adopt, Maya Dewan, Rajit K Basu, Erin Bennett, Lily B Glater-Welt, Mark Hall, Benson S Hsu, Lia Lowrie, Venessa Lynn Pinto, Alexandre T Rotta, Edward Seferian, Linda Siegel, Heather A Wolfe, Vijay Srinivasan Jan 2025

Evidence-Based Evaluation To Promote High-Value Care In Pediatric Critical Care: It Is Time To Fully Adopt, Maya Dewan, Rajit K Basu, Erin Bennett, Lily B Glater-Welt, Mark Hall, Benson S Hsu, Lia Lowrie, Venessa Lynn Pinto, Alexandre T Rotta, Edward Seferian, Linda Siegel, Heather A Wolfe, Vijay Srinivasan

Faculty, Staff and Students Publications

Introduction: Evidence-based recommendations for high-value care in pediatric critical care are needed. We sought to develop recommendations to identify unnecessary interventions, enhance outcomes, and promote efficient, patient-centered practices.

Methods: Using a modified Delphi process, a multi-institutional panel of pediatric intensivists from a national pediatric critical care quality improvement group identified 30 potential topics and selected 20 high- and medium-priority topics for further evaluation, and narrowed them to 10 by consensus voting. A structured scoping review of literature published between 2014 and 2023 identified 10 practices, which were critically assessed using the PICOST framework. The panel selected 5 priority recommendations based …


Validating A Novel Capability Of Assessing Pathways Of Animal Water Gain And Loss, Zachary T. Steele, Karen Caceres, Zachary A. David, Lisa M. Shollenberger, Alexander R. Gerson, Seth D. Newsome, John P. Whiteman Jan 2025

Validating A Novel Capability Of Assessing Pathways Of Animal Water Gain And Loss, Zachary T. Steele, Karen Caceres, Zachary A. David, Lisa M. Shollenberger, Alexander R. Gerson, Seth D. Newsome, John P. Whiteman

Biological Sciences Faculty Publications

Understanding variations in the routes by which wild animals gain and lose water is challenging, and common methods require longitudinal sampling, which can be prohibitive. However, a new approach uses Δ′¹⁷OBW (Δ′¹⁷O of animal body water), calculated from measurements of δ′¹⁷O and δ′¹⁸O in a single sample, as a natural tracer of water flux. Δ′¹⁷OBW is promising, but its relationship to organismal variables such as metabolic rate and water intake have not been validated. Here, we continuously measured oxygen influxes and effluxes of captive deer mice (Peromyscus maniculatus), and manipulated their water intake and metabolic rate. We used …


Heterotrophy Of Particulate Organic Matter Subsidies Contributes To Divergent Bleaching Responses In Tropical Sclaractinian Corals, Connor R. Love, Kelly E. Speare, Michael D. Fox, Veronica Z. Radice, Kelton W. Mcmahon, Gretchen E. Hofmann,, David L. Valentine, Marie E. Strader Jan 2025

Heterotrophy Of Particulate Organic Matter Subsidies Contributes To Divergent Bleaching Responses In Tropical Sclaractinian Corals, Connor R. Love, Kelly E. Speare, Michael D. Fox, Veronica Z. Radice, Kelton W. Mcmahon, Gretchen E. Hofmann,, David L. Valentine, Marie E. Strader

Biological Sciences Faculty Publications

Heterotrophic feeding on plankton and particulate organic matter (POM) by tropical Scleractinian corals is known to aid in the resistance and recovery from thermally induced bleaching. However, the relative importance of heterotrophy in promoting bleaching resistance and recovery is likely to vary based on ecological context and the severity of heat stress. In 2019, the Pacific Island of Mo'orea experienced mass coral mortality during a widespread marine heatwave. Many Acropora hyacinthus colonies on the shallow reef slope (5 m) were resistant to bleaching, while colonies on the deeper fore reef (14 m) often bleached and subsequently recovered, despite similar thermal …


A Murine Model Of Gestational Diabetes Reveals Masld Risk And Alterations In Markers Of Hepatic Mitochondrial Metabolism, Grace E Shryack, Alexa A Krause, Simone Hernandez Ruano, Laura C Schulz, Kathleen A Pennington, R Scott Rector Jan 2025

A Murine Model Of Gestational Diabetes Reveals Masld Risk And Alterations In Markers Of Hepatic Mitochondrial Metabolism, Grace E Shryack, Alexa A Krause, Simone Hernandez Ruano, Laura C Schulz, Kathleen A Pennington, R Scott Rector

Faculty, Staff and Students Publications

Introduction: Gestational Diabetes Mellitus (GDM) impacts roughly 1 in 7 pregnancies and results in metabolic dysfunction-associated steatotic liver disease (MASLD) in 30% of these women. Nonetheless, there exists a dearth of investigation into the relationship between GDM and MASLD. Here, we sought to investigate the potential role of hepatic mitochondrial function in GDM and MASLD.

Methods: One week prior to conception and throughout pregnancy, mice were fed either a low-fat control diet (CD) or a high-fat, high-sucrose (HFHS) diet to induce an established model of GDM. Maternal livers were collected at day 0, 6.5, 13.5 and 17.5 of pregnancy. Hepatic …


Hair Growth Rate Estimation In North American Ursids, Jennifer H. Stern, Karyn D. Rode, Craig A. Stricker, Sheriden Ploof, Cindy L. J. Roberts, Celess Edinger, Mary Humbyrd, Nate Wagner, Megan A. Owen, John P. Whiteman, Thea Bechshoft, Brent White, Kristin L. Laidre Jan 2025

Hair Growth Rate Estimation In North American Ursids, Jennifer H. Stern, Karyn D. Rode, Craig A. Stricker, Sheriden Ploof, Cindy L. J. Roberts, Celess Edinger, Mary Humbyrd, Nate Wagner, Megan A. Owen, John P. Whiteman, Thea Bechshoft, Brent White, Kristin L. Laidre

Biological Sciences Faculty Publications

The feeding ecology of wildlife populations has important implications for individual health, population productivity and distribution patterns. For ursids (bears), food resources and feeding behaviour primarily affect population dynamics via effects on cub production and survival. Much of what is known about the feeding ecology of bears is based on analyses of tissues collected from capture-based research efforts, harvested animals or non-invasive approaches. However, inference about diet from hair has been limited by a lack of quantitative data on the timing of the moult and hair growth rates. We conducted a study to develop and test two methods of quantifying …


Qualitative And Quantitative Analysis Of A Novel Dental Health Education Program To Improve Dental Care Utilization By Bhutanese-, Burmese-, And Swahili-Speaking Refugees In A Midwestern United States City, Chandra Swanson, Katherine Gordon, Kelly Kreisler, Elizabeth Montgomery Collins Jan 2025

Qualitative And Quantitative Analysis Of A Novel Dental Health Education Program To Improve Dental Care Utilization By Bhutanese-, Burmese-, And Swahili-Speaking Refugees In A Midwestern United States City, Chandra Swanson, Katherine Gordon, Kelly Kreisler, Elizabeth Montgomery Collins

2020-Current year OA Pubs

No abstract provided.


Integrating Mapk Pathway Inhibition Into Standard-Of-Care Therapy For Pediatric Low-Grade Glioma, Erin E Crotty, Aimee A Sato, Mohamed S Abdelbaki Jan 2025

Integrating Mapk Pathway Inhibition Into Standard-Of-Care Therapy For Pediatric Low-Grade Glioma, Erin E Crotty, Aimee A Sato, Mohamed S Abdelbaki

2020-Current year OA Pubs

Pediatric low-grade gliomas (pLGG) are a group of tumors largely driven by alterations in a single genetic pathway, known as the RAS-RAF-mitogen-activated protein kinase (MAPK) pathway. Recent biologic insights and therapeutic targeting of MAPK-alterations have dramatically shifted the treatment approach in pLGG. While chemotherapy remains front-line therapy for unresectable pLGG in most scenarios (with the notable exception of


The Impact Of Age-Friendly Policy On New York State: How Executive Order-190 And Executive Order-23 Shape Community Development For All Ages, Trista Bercarich Jan 2025

The Impact Of Age-Friendly Policy On New York State: How Executive Order-190 And Executive Order-23 Shape Community Development For All Ages, Trista Bercarich

West Chester University Graduate Theses, Dissertations, and Final Projects

The demographic shift toward an aging population has created an urgent need for policies that promote inclusive, livable communities for all ages. This quantitative study examined New York State’s implementation of Age-Friendly policy through Executive Order 190 (2018) and Executive Order 23 (2022), which collectively advance the integration of health, accessibility and community participation across state and local systems. Guided by environmental gerontology and psychology, aging in place and successful aging frameworks, this research utilized an adapted version of the AARP Livable Communities Survey to assess residents’ perceptions of livability with the eight AARP domains. The cross-sectional online survey (n …


Health Center Patient Satisfaction: Pre, During, And Post Covid-19, Patricia A. Stroup, Patricia Stroup Jan 2025

Health Center Patient Satisfaction: Pre, During, And Post Covid-19, Patricia A. Stroup, Patricia Stroup

West Chester University Graduate Theses, Dissertations, and Final Projects

This study aims to evaluate patients' attitudes toward healthcare services in a predominantly Hispanic population at an urban health center serving a significantly disadvantaged population.  This center is in one of the poorest areas of the city and has one of the highest diabetes rates in the nation. For over 50 years, Federal health centers have provided care to inner-city, rural, homeless and public housing residents. They provide care to vulnerable populations that would not otherwise be available in medically underserved communities. Central to overcoming disparities is assuring patient satisfaction with their healthcare. This study evaluates patients' satisfaction with the …


Final Cruise Report: Tn401, Roxanne A. Beinart, Shawn Arellano, Craig Young Jan 2025

Final Cruise Report: Tn401, Roxanne A. Beinart, Shawn Arellano, Craig Young

Graduate School of Oceanography Faculty Publications

No abstract provided.


Deletions In The Cdkl5 5′ Untranslated Region Lead To Cdkl5 Deficiency Disorder, Isabel Haviland, Ralph D Hector, Lindsay C Swanson, Aubrie Soucy Verran, Emma Sherrill, Zoë Frazier, Annemarie M Denny, Jenna Lucash, Bo Zhang, Holly A Dubbs, Eric D Marsh, Judith L Weisenberg, Helen Leonard, Milena Crippa, Francesca Cogliati, Silvia Russo, Bernhard Suter, Rajsekar Rajaraman, Alan K Percy, John M Schreiber, Scott Demarest, Timothy A Benke, Maya Chopra, Timothy W Yu, Heather E Olson Jan 2025

Deletions In The Cdkl5 5′ Untranslated Region Lead To Cdkl5 Deficiency Disorder, Isabel Haviland, Ralph D Hector, Lindsay C Swanson, Aubrie Soucy Verran, Emma Sherrill, Zoë Frazier, Annemarie M Denny, Jenna Lucash, Bo Zhang, Holly A Dubbs, Eric D Marsh, Judith L Weisenberg, Helen Leonard, Milena Crippa, Francesca Cogliati, Silvia Russo, Bernhard Suter, Rajsekar Rajaraman, Alan K Percy, John M Schreiber, Scott Demarest, Timothy A Benke, Maya Chopra, Timothy W Yu, Heather E Olson

Faculty, Staff and Students Publications

Pathogenic variants in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with CDKL5 deficiency disorder (CDD), a severe X-linked developmental and epileptic encephalopathy. Deletions affecting the 5' untranslated region (UTR) of CDKL5, which involve the noncoding exon 1 and/or alternatively spliced first exons (exons 1a-e), are uncommonly reported. We describe genetic and phenotypic characteristics for 15 individuals with CDKL5 partial gene deletions affecting the 5' UTR. All individuals presented characteristic features of CDD, including medically refractory infantile-onset epilepsy, global developmental delay, and visual impairment. We performed RNA sequencing on fibroblast samples from three individuals with small deletions involving exons 1 …


Testosterone Plus Lifestyle Therapy Improves Skeletal Muscle Glycolysis In Older Men With Obesity And Hypogonadism, Viola Viola, Marlene Aguilar, Maria Liza Duremdes Nava, Alessandra Celli, Reina Armamento-Villareal, Yoann Barnouin, Nicola Napoli, Nagireeddy Putluri, Clifford Qualls, Dennis T Villareal Jan 2025

Testosterone Plus Lifestyle Therapy Improves Skeletal Muscle Glycolysis In Older Men With Obesity And Hypogonadism, Viola Viola, Marlene Aguilar, Maria Liza Duremdes Nava, Alessandra Celli, Reina Armamento-Villareal, Yoann Barnouin, Nicola Napoli, Nagireeddy Putluri, Clifford Qualls, Dennis T Villareal

Faculty, Staff and Students Publications

Objective: Weight loss in older men with obesity and hypogonadism accelerates musculoskeletal decline, yet the underlying metabolic mechanisms remain unclear. Testosterone replacement therapy (TRT), when added to lifestyle therapy (LT), mitigates this decline, but its metabolic basis has not been defined. We examined skeletal muscle metabolomic adaptations to LT with or without TRT, focusing on glycolysis, the pentose phosphate pathway (PPP), the tricarboxylic acid (TCA) cycle, and carnitine metabolism to identify dominant pathways of metabolic adaptation.

Design: Randomized, double-blind, placebo-controlled trial (LITROS).

Methods: Eighty-three men aged 65 years or older with obesity (BMI ≥30 kg/m2), hypogonadism (testosterone < 10.4 nmol/L), and frailty (Physical Performance Test score ≤31) were randomized to 26 weeks of LT plus TRT (LT+TRT) or LT plus placebo (LT+Pbo). A metabolomic substudy was performed in 44 participants, who underwent serial biopsies of the vastus lateralis for targeted LC-MS/MS analysis of intermediates in glycolysis, PPP, TCA cycle, and carnitine metabolism.

Results: Among the …


Relationships Of Personality Traits With The Taxonomic Composition Of The Gut Microbiome Among Psychiatric Inpatients, William Orme, Sandra L Grimm, Divya S N Vella, J Christopher Fowler, B Christopher Frueh, Benjamin L Weinstein, Joseph Petrosino, Cristian Coarfa, Alok Madan Jan 2025

Relationships Of Personality Traits With The Taxonomic Composition Of The Gut Microbiome Among Psychiatric Inpatients, William Orme, Sandra L Grimm, Divya S N Vella, J Christopher Fowler, B Christopher Frueh, Benjamin L Weinstein, Joseph Petrosino, Cristian Coarfa, Alok Madan

Faculty, Staff and Students Publications

Objective: Through the brain-gut-microbiome axis, myriad psychological functions that affect behavior share a dynamic, bidirectional relationship with the intestinal microbiome. Little is known about the relationship between personality-a stable construct that influences social- and health-related behaviors-and the bacterial ecosystem. The authors of this exploratory study examined the relationship between general and maladaptive personality traits and the composition of the gut microbiome.

Methods: In total, 105 psychiatric inpatients provided clinical data and fecal samples. Personality traits were measured with the five-factor model of personality, the Structured Clinical Interview for DSM-IV Axis II Personality Disorders, and the Personality Inventory for DSM-5; 16S …


The Perfect Storm: Unraveling The Interplay Of Genetic Predisposition And Viral Triggers In Type 1 Diabetes Pathogenesis, Daniel A Veronese-Paniagua, Jeffrey R Millman Jan 2025

The Perfect Storm: Unraveling The Interplay Of Genetic Predisposition And Viral Triggers In Type 1 Diabetes Pathogenesis, Daniel A Veronese-Paniagua, Jeffrey R Millman

2020-Current year OA Pubs

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the T cell-mediated destruction of insulin-secreting pancreatic β cells, leaving patients reliant on exogenous insulin to establish normoglycemia. Despite advancements in glucose management, the precise pathological mechanisms linking genetic predisposition and environmental triggers to the loss of immune tolerance remain incompletely understood, hindering the development of preventative therapies. This comprehensive review synthesizes clinical, experimental, and epidemiological data to detail the intricate pathogenesis of T1D, focusing on the convergence of autoimmunity, high-risk genetics, and enteroviral infection. We discuss how T1D is fundamentally a disease caused by failures in central and …


Molecular Chaperones At The Host-Virus Interface: Heat Shock Protein Roles In Hiv-1 And Emerging Insights For Hiv-2 And Dual Infection, Sabastine Eugene Arthur, Kirk Klogo, Emmanuel Kobina Mensah, Maame Ama Pentsiwa Cudjoe, Adomia Baaba Mensah, Nyamekye Amoabeng Ankrah, Catherine Laaripuoh Omosule, Evelyn Yayra Bonney, George Boateng Kyei Jan 2025

Molecular Chaperones At The Host-Virus Interface: Heat Shock Protein Roles In Hiv-1 And Emerging Insights For Hiv-2 And Dual Infection, Sabastine Eugene Arthur, Kirk Klogo, Emmanuel Kobina Mensah, Maame Ama Pentsiwa Cudjoe, Adomia Baaba Mensah, Nyamekye Amoabeng Ankrah, Catherine Laaripuoh Omosule, Evelyn Yayra Bonney, George Boateng Kyei

2020-Current year OA Pubs

Heat shock proteins (HSPs) are essential molecular chaperones involved in protein folding, cellular stress responses, and homeostasis. Recent studies reveal their critical and dual roles in the human immunodeficiency virus (HIV) life cycle, both promoting and restricting viral replication, latency, and immune modulation. This review synthesizes current evidence on how key HSP families, HSP70, HSP90, and HSP40, interact with HIV proteins such as Tat, Rev, Nef, and Vpx, affecting viral transcription, protein trafficking, and latency. We also highlight Heat Shock Factor 1 (HSF1) as a direct regulator of the HIV-1 long terminal repeat (LTR), facilitating latency reversal via recruitment of …


ปัจจัยคัดสรรที่สัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล, นวภัทร คงดี, ศิริพันธุ์ สาสัตย์ Jan 2025

ปัจจัยคัดสรรที่สัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล, นวภัทร คงดี, ศิริพันธุ์ สาสัตย์

Journal of Nursing Research, Innovation, and Health

รูปแบบการวิจัยเชิงบรรยายวิเคราะห์ความสัมพันธ์ วัตถุประสงค์: 1) เพื่อศึกษาความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล 2) เพื่อศึกษาความสัมพันธ์ระหว่าง เพศ ภาวะเปราะบาง ภาวะโภชนาการ ภาวะซึมเศร้า และจำนวนชนิดของยาที่ใช้ประจำ กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล กลุ่มตัวอย่าง คือ ผู้ที่มีอายุเกิน 60 ปีบริบูรณ์ขึ้นไปที่พ้นระยะเฉียบพลัน มีสภาวะทางการแพทย์คงที่และมีสัญญาณชีพปกติ ทั้งเพศชายและเพศหญิงที่มารับบริการในแผนกผู้ป่วยในโรงพยาบาลระดับตติยภูมิ 3 แห่ง โรงพยาบาลเลิดสิน โรงพยาบาลเจริญกรุงประชารักษ์ และโรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย จำนวน 93 คน เครื่องมือที่ใช้ในการเก็บข้อมูล ได้แก่ แบบสอบถามข้อมูลส่วนบุคคล แบบประเมินความสามารถในกิจวัตรขั้นพื้นฐานของผู้สูงอายุ แบบประเมินภาวะรู้คิด แบบประเมินภาวะเปราะบางอย่างง่าย วิเคราะห์ข้อมูลโดยใช้สถิติพรรณนา สถิติสหสัมพันธ์อีต้า และสถิติสหสัมพันธ์ของ สเปียร์แมน

ผลการศึกษา: พบว่า 1) ผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาลมีความต้องการฟื้นฟูสมรรถภาพในระดับปานกลาง (mean = 55.04, SD = 10.55) 2) ภาวะเปราะบาง มีความสัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาลอย่างมีนัยสำคัญทางสถิติ (=.259, p< .05) 3) ภาวะโภชนาการ มีความสัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาลอย่างมีนัยสำคัญทางสถิติ (rs = 313, p< .05) 4) ภาวะซึมเศร้า มีความสัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาลอย่างมีนัยสำคัญทางสถิติ (rs = -247, p< .05) 5) จำนวนชนิดของยาที่ใช้ประจำ มีความสัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล อย่างมีนัยสำคัญทางสถิติ (rs = -264, p< .05) และ 6) เพศ ไม่มีความสัมพันธ์กับความต้องการฟื้นฟูสมรรถภาพผู้ป่วยสูงอายุที่มีภาวะพึ่งพิงที่เข้าสู่การดูแลระยะกลางในโรงพยาบาล

สรุป: ควรจัดทำกิจกรรมการฟื้นฟูสมรรถภาพเป็นรายบุคคลตามความต้องการฟื้นฟูสมรรถภาพทั้งด้านร่างกายด้านจิตใจ และจัดให้มีกิจกรรมนันทนาการเพิ่มจากการบริการขั้นพื้นฐานการดูแลระยะกลาง เพื่อมุ่งเน้นให้ผู้ป่วยได้เข้าใจคุณค่าที่สำคัญของชีวิตและรับรู้ถึงประโยชน์ของการฟื้นฟูสมรรถภาพ


Artificial Intelligence And Energy Democracy, Joel B. Eisen, Heather E. Payne Jan 2025

Artificial Intelligence And Energy Democracy, Joel B. Eisen, Heather E. Payne

Law Faculty Publications

Artificial intelligence (AI) is quickly transforming many professional activities, and the electric grid has already started to see adverse impacts from its use, such as the burgeoning demand for electricity from data centers. This Article acknowledges these impacts, but also demonstrates that AI can be put to beneficial use on the grid. It proposes and describes a specific use of AI: assisting citizen intervenors in public utility commission (PUC) proceedings, who currently face barriers to participation due to the technical complexity and confidentiality imposed by monopoly utilities. The Article describes how AI can assist intervenors to overcome the barriers to …


Antenatal Interventions To Improve Breastfeeding In High-Risk Pregnancies: An Outpatient Clinic Perspective, Lina Saeday Jan 2025

Antenatal Interventions To Improve Breastfeeding In High-Risk Pregnancies: An Outpatient Clinic Perspective, Lina Saeday

Doctor of Nursing Practice Projects

High-risk pregnancies often face unique challenges when it comes to breastfeeding, yet few antenatal interventions specifically target this population. This quality improvement project aimed to improve breastfeeding knowledge, confidence, and attitudes among high-risk pregnant individuals through a brief educational intervention. Ten participants between 33 and 36 weeks gestation with diagnoses including GDM, gestational hypertension, multiple gestations and IVF pregnancies were recruited from an outpatient maternal-fetal medicine clinic. A printed educational brochure and a brief in-person teaching session were provided. Participants completed pre- and post-intervention surveys assessing their knowledge, perceived support, and attitudes toward breastfeeding. Post-intervention survey responses revealed statistically significant …


Addressing Mental Healthcare Barriers Among Bipoc Perinatal Patients In A Community Health Setting, Aimee Nguyen, Ezinne Ndibeshe, Vedika Iyer Jan 2025

Addressing Mental Healthcare Barriers Among Bipoc Perinatal Patients In A Community Health Setting, Aimee Nguyen, Ezinne Ndibeshe, Vedika Iyer

Doctor of Nursing Practice Projects

Objective. BIPOC (Black, Indigenous, and People of Color) perinatal patients often face systemic, cultural, and logistical barriers to accessing mental health care during pregnancy and postpartum. These challenges contribute to disparities in outcomes, yet patient perspectives remain underrepresented in community health settings. This quality improvement initiative aimed to identify key barriers, raise awareness about perinatal mental health, and improve access to care at a community health clinic in Shoreline, Washington. A culturally inclusive educational handout was developed to support awareness and connect patients with mental health resources.

Methods. A mixed-methods approach was used to explore barriers both quantitatively and qualitatively. …


Optimizing Patient Outcomes: The Essential Role Of A Consolidated Nutrition Platform, Hugo Lam Jan 2025

Optimizing Patient Outcomes: The Essential Role Of A Consolidated Nutrition Platform, Hugo Lam

Doctor of Nursing Practice Projects

Background and Purpose: Current research identifies a gap in the data regarding electronic health records (EHRs), signage, and digital tools to improve outcomes for patients on modified diets, as well as a lack of government reports on clinically related events (Hoggle et al., 2006; Limketkai et al., 2021; Prgomet et al., 2019). EHRs can facilitate data sharing, but often overlook clinical realities and user needs, which leads to inefficiencies in nutritional care. This quality improvement project examines the experiences of bedside providers in acute trauma settings to inform evidence-based recommendations for enhancing nutritional care practices and system design.

Methods: This …


Utilizing Integrative Medicine Services For Yoga To Reduce Cancer Related Fatigue, Leah R. Yeager Jan 2025

Utilizing Integrative Medicine Services For Yoga To Reduce Cancer Related Fatigue, Leah R. Yeager

DNP Projects

Background: Cancer related fatigue (CRF) is one of the most prevalent and distressing side effects experienced by individuals undergoing cancer treatment. In fact, many patients report CRF as more debilitating than pain itself. CRF is characterized by persistent, severe exhaustion that is not alleviated by sleep and is not linked to prior exertion. Despite its widespread impact, the options available to manage CRF are limited, typically including practices like good sleep hygiene, balanced nutrition, mindfulness, and supplements. Integrative medicine, particularly yoga, has emerged as a promising intervention for reducing CRF. However, yoga is underutilized as a therapeutic approach to combat …


Nurse-Led Cbt For Depression In Heart Transplant Patients: A Feasibility Study, Matthew R. Wallace Jan 2025

Nurse-Led Cbt For Depression In Heart Transplant Patients: A Feasibility Study, Matthew R. Wallace

DNP Projects

Background: Heart transplant recipients are at an elevated risk of experiencing depressive symptoms compared to the general population. Those with depression post-transplant face increased complications, e.g., infection, organ rejection, prolonged hospitalization, and higher mortality rates. However, specific psychotherapeutic interventions tailored for heart transplant recipients remain limited. Nevertheless, there is substantial evidence supporting the effectiveness of various interventions for adults with heart failure, a condition frequently diagnosed in these patients. This suggests that successful strategies for managing depressive symptoms in heart failure patients could be adapted for heart transplant recipients.

Purpose: The purpose of this project was to evaluate …


Implementation And Evaluation Of Diet And Physical Activity Screening Tools For Adults With Type 2 Diabetes Mellitus In Primary Care, Ashley O. Dalton Jan 2025

Implementation And Evaluation Of Diet And Physical Activity Screening Tools For Adults With Type 2 Diabetes Mellitus In Primary Care, Ashley O. Dalton

DNP Projects

Background: Only half of individuals with type 2 diabetes mellitus (T2DM) have a hemoglobin A1C (HbA1c) of less than 7%, indicating poor glycemic control and contributing to a global diabetes epidemic. Diabetes is considered a diet-sensitive disease and an individual’s diabetes-related nutrition knowledge is one of the most challenging aspects of the treatment plan. Empirical evidence supports that a combination of dietary and physical activity interventions is more effective than nutrition education alone. Performing a dietary evaluation is fundamental to establishing nutrition goals. The use of the Starting the Conversation (STC) tool, which assesses an individual’s dietary practices, and Physical …


Introducing An Eating Disorder Protocol In The Pediatric Primary Care Setting, Brandi Bozarth Jan 2025

Introducing An Eating Disorder Protocol In The Pediatric Primary Care Setting, Brandi Bozarth

DNP Projects

Background: The incidence of eating disorders has been on the rise, often beginning in adolescence and continuing well into adulthood. Consequences of untreated disrupted eating patterns can affect multiple body systems and are responsible for thousands of deaths annually. Despite these facts, research and data regarding eating disorders in adolescent patients are severely deficient. There is also a lack of standardization regarding assessing eating disorders in the pediatric primary care setting, as there are no specific guidelines or screening processes recommended by the American Academy of Pediatrics for the detection of eating disorders.

Purpose: The purpose of this project is …


Evaluating The Implementation Of Social Determinants Of Health Screening In An Interdisciplinary Clinic, Taylor M. Adams Jan 2025

Evaluating The Implementation Of Social Determinants Of Health Screening In An Interdisciplinary Clinic, Taylor M. Adams

DNP Projects

Background: Social Determinants of Health (SDOH), including food, housing, interpersonal violence, and transportation are non-medical problems that can influence health outcomes (World Health Organization, 2020). Low-income minorities and public-payer groups are at considerable higher risk for social needs. Collaboration within the community can improve health outcomes (Sulley et al., 2021). A literature review revealed limited evidence of screening in dental clinic settings. Failure to identify and address SDOH needs in this population can lead to poorer health outcomes.

Purpose: The purpose of this quality improvement project was to implement and evaluate social determinants of health screening and evaluate the …


Evaluating The Effect Of A Mindfulness App On Pediatric Nurses Caring For Adolescent Patients Diagnosed With Disordered Eating, Kaitlyn Green Jan 2025

Evaluating The Effect Of A Mindfulness App On Pediatric Nurses Caring For Adolescent Patients Diagnosed With Disordered Eating, Kaitlyn Green

DNP Projects

Abstract

Background. The health and wellbeing of nurses are affected by the demands of their workplace and the people that they care for. In turn, nurses’ wellbeing affects their work and patient outcomes. There are opportunities to address certain workplace structures, systems, and policies that create stressors and lead to burnout, fatigue, and poor mental and physical health. For nurses to continue to provide quality care in environments that have increasing demands, they must first feel healthy, well, and supported themselves. Healthcare leaders have a role in ensuring the wellbeing of their nursing staff. Compassion fatigue is a large focus …


America’S Hidden Heroine: The Revolutionary Experience Of Deborah Sampson, Rebecca A. Dawson Jan 2025

America’S Hidden Heroine: The Revolutionary Experience Of Deborah Sampson, Rebecca A. Dawson

Pell Scholars and Senior Theses

This thesis explores the life of Deborah Sampson, a female soldier in the Fourth Massachusetts Regiment during the American Revolution. The author discusses how and why Sampson joined the military, the challenges she had to overcome, and her experience as the first American woman to lead a public lecture tour. Sampson continues to serve as an embodiment of resilience, courage, and the Spirit of ‘76.


Fusarium Head Blight Resistance Genes Impact Agronomic Performance, Flavor, Milling, And Baking Traits In Soft Red Winter Wheat, Joyce Morris Jan 2025

Fusarium Head Blight Resistance Genes Impact Agronomic Performance, Flavor, Milling, And Baking Traits In Soft Red Winter Wheat, Joyce Morris

Theses and Dissertations--Plant and Soil Sciences

Fusarium Head Blight (FHB) is an economically devastating disease of wheat (Triticum aestivum L.) causing low yields and poor quality. FHB, caused by Fusarium graminearum, disrupts the grain filling phase and results in bleached spikes and shriveled seeds. Deoxynivalenol (DON) is a mycotoxin produced by the fungal pathogen when it infects the plant; DON is harmful when consumed by humans and causes feed rejection in livestock. Using FHB resistant varieties and timely applications of fungicides is the optimum strategy for management of this disease. However, there has been little research focusing on the impact of FHB resistance genes …


Scientific Kenyon: Neuroscience Edition (Full Issue) Jan 2025

Scientific Kenyon: Neuroscience Edition (Full Issue)

Scientific Kenyon: The Neuroscience Edition

No abstract provided.


Forget The All-Nighter: How Sleep Boosts Memory Consolidation, Paula Sorić Jan 2025

Forget The All-Nighter: How Sleep Boosts Memory Consolidation, Paula Sorić

Scientific Kenyon: The Neuroscience Edition

No abstract provided.