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2025

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Motivators And Barriers To Healthy Food Consumption: Qualitative Study With Gen Z Living In Bratislava, Emel Yarimoglu, Lucia Vilcekova Apr 2025

Motivators And Barriers To Healthy Food Consumption: Qualitative Study With Gen Z Living In Bratislava, Emel Yarimoglu, Lucia Vilcekova

AMTP Proceedings 2025

People in Europe have been caring about physical activity, healthy eating, and healthy body weight. The study aimed to explore the motivators and barriers to healthy food consumption among university students living in Bratislava, Slovakia. Qualitative research was conducted with sixteen students, and data were collected by written text. Self-reported written data were collected by convenience sampling and analyzed via content analysis. Four motivators of healthy food consumption were revealed (personal appearance, health-consciousness, physical activity, and social), and four barriers to healthy food consumption were obtained (functional, personal, psychological, and social). This research is original since it demonstrated motivators and …


Localization Module In User Experience Questionnaire For Cross Cultural Website Design, Nurhayati Mohd Husni, Nur Atiqah Sia Abdullah Apr 2025

Localization Module In User Experience Questionnaire For Cross Cultural Website Design, Nurhayati Mohd Husni, Nur Atiqah Sia Abdullah

Malaysian Journal of Computing (MJoC)

The importance of User Interface (UI) and User Experience (UX) in ensuring the practicality and usability of websites for users is well-recognized. The User Experience Questionnaire (UEQ) is widely employed to evaluate these aspects of a product, ensuring linguistic and cultural appropriateness for its target locale based on country, region, or language. However, the UEQ lacks a module specifically designed to assess the localization properties of a product. This research aims to extend the UEQ by introducing a localization module that adheres to cross-cultural design principles. The study involved a systematic literature review to identify potential items for the localization …


Ethiopia Humanitarian Violence Against Children And Youth Survey, 2024: Data-To-Action Workshop Report, Yadeta Dessie, Dagim Habteyesus, Yohannes Dibaba Wado, Abir Nur, Stella Muthuri, Peter Kisaakye, Bonnie Wandera, Gloria Seruwagi, Francis Obare, Andres Villaveces, Michelle Hynes, Misrak Mohammed, Mulualem Desta, Chi-Chi Undie Apr 2025

Ethiopia Humanitarian Violence Against Children And Youth Survey, 2024: Data-To-Action Workshop Report, Yadeta Dessie, Dagim Habteyesus, Yohannes Dibaba Wado, Abir Nur, Stella Muthuri, Peter Kisaakye, Bonnie Wandera, Gloria Seruwagi, Francis Obare, Andres Villaveces, Michelle Hynes, Misrak Mohammed, Mulualem Desta, Chi-Chi Undie

Humanitarian Task Force

The Government of Ethiopia’s Refugees and Returnees Service (RRS) officials, various government ministry delegates, representatives from International and national Non-Governmental Organisations, UN bodies, and various delivery partners, came together for a Data to Action (D2A) workshop in Addis Ababa from November 19th to 21st, 2024. During this workshop, participants prioritized violence prevention and response activities, directly informed by the HVACS data. This was achieved by translating the Ethiopia HVACS findings into key indicators that were then mapped into actionable next steps by linking this data to the INSPIRE: Seven Strategies for Ending Violence Against Children technical package and the Child …


What Do We Know About Insect Responses To Global Change? A Review Of Meta-Analyses On Global Change Drivers, Mayra C. Vidal, Mariana Abarca, Kristi Backe, Anne E. Curé, Deborah L. Finke, Amanda M. Koltz, Alycia C.R. Lackey, J. Christina Mitchell, Rebecca M. Prather, Ellen A.R. Welti, Gina M. Wimp, Shannon M. Murphy Apr 2025

What Do We Know About Insect Responses To Global Change? A Review Of Meta-Analyses On Global Change Drivers, Mayra C. Vidal, Mariana Abarca, Kristi Backe, Anne E. Curé, Deborah L. Finke, Amanda M. Koltz, Alycia C.R. Lackey, J. Christina Mitchell, Rebecca M. Prather, Ellen A.R. Welti, Gina M. Wimp, Shannon M. Murphy

Biological Sciences: Faculty Publications

1. Global change is causing major declines in biodiversity, especially of insects. Scientific interest in global change impacts on insects has increased in recent years, resulting in many different meta-analyses examining questions within this topic.

2. We performed a comprehensive review of meta-analyses examining the effects of global change stressors on insects to identify well-studied questions and gaps in our knowledge and synthesise the responses of insects to those stressors. We identified 75 meta-analyses that fit our scope, accounting for 905 meta-results and spanning 18 global change stressors.

3. Our synthesis identified several global change stressors that are relatively well-studied …


Addressing Agricultural Mulch Challenges In Specialty Crop Production, Caleb David Wehrbein Apr 2025

Addressing Agricultural Mulch Challenges In Specialty Crop Production, Caleb David Wehrbein

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Agricultural mulches are an essential yield-boosting tool in modern specialty crop production that provide weed suppression, temperature modulation, and moisture conservation functions. Polyethylene plastic mulches are the most widely used agricultural mulch but are not sustainable given their pollutive effect on the environment and challenges associated with recycling. In order to move towards a more sustainable industry, plastic mulch use in agriculture should become more efficient or replaced with more environmentally friendly alternatives. Biodegradable mulches may be a suitable alternative to plastic mulch, but they are often less durable and prematurely degrade in field conditions. Considering this, my dissertation research …


Coyote (Canis Latrans) Macronutrient Consumption And Diet Relative To Seasonality And Urbanization, Katherine C. B. Weiss, Sean C. P. Coogan, Pierre Deviche, Jesse S. Lewis, Savage C. Hess, Jan Schipper, Eric G. Strauss, Beckett Sterner Apr 2025

Coyote (Canis Latrans) Macronutrient Consumption And Diet Relative To Seasonality And Urbanization, Katherine C. B. Weiss, Sean C. P. Coogan, Pierre Deviche, Jesse S. Lewis, Savage C. Hess, Jan Schipper, Eric G. Strauss, Beckett Sterner

Biology Faculty Works

Diet selection informs the health, fitness, and behavior of wild predators. Due to assumptions that vertebrate prey contains similar compositions of macronutrients (i.e., protein, carbohydrates, and lipids), whole prey items traditionally define carnivore diets. However, increasing evidence suggests that prey differ in terms of their macronutrient compositions, particularly relative to body size. Furthermore, omnivorous predators, like coyotes (Canis latrans), integrate both prey and nonprey diet items whose macronutrient compositions vary. This is particularly important in urbanized systems, which introduce or alter the distributions of prey (e.g., domestic pets) and nonprey (e.g., ornamental plants) foods in ways that contribute …


Ucc Minutes 4-1-25, Angela Brock Apr 2025

Ucc Minutes 4-1-25, Angela Brock

UCC Agendas/Minutes

No abstract provided.


Law In Bloom: The Roots Of Legal Consciousness And Negotiation In Philadelphia Community Gardens, Vanessa Amsinger , '25 Apr 2025

Law In Bloom: The Roots Of Legal Consciousness And Negotiation In Philadelphia Community Gardens, Vanessa Amsinger , '25

Senior Theses, Projects, and Awards

This thesis examines how legal consciousness, self-governance, and social networks shape power, participation, and belonging in the Southwark Queen Village Community Garden in South Philadelphia, Pennsylvania. I draw on theories of legal pluralism and network theory to analyze archival documents, participant observation, and semi-structured interviews with garden members and leadership. I show that gardeners navigate overlapping formal rules and informal hierarchies, appearing in the form of bylaws, land trust agreements, social ties, and embodied practices, that together produce a complex web of legal consciousness inside the space. Mechanisms of self-governance, like plot assignments and leadership elections, often reinforce social hierarchies …


You Thought You Ate: How Capitalism Constructs Black Women’S Body Image And Relationship To Food, Nia Y. Todd , '25 Apr 2025

You Thought You Ate: How Capitalism Constructs Black Women’S Body Image And Relationship To Food, Nia Y. Todd , '25

Senior Theses, Projects, and Awards

No abstract provided.


The Experiences Of Disabled People In Physical Education, Wesley J. Wilson (Editor), Justin A. Haegele (Editor) Apr 2025

The Experiences Of Disabled People In Physical Education, Wesley J. Wilson (Editor), Justin A. Haegele (Editor)

Human Movement Studies & Special Education Faculty Books

Bringing together a set of first- person accounts of physical education from the perspectives of disabled children and adults, this book puts disabled people’s voices in the foreground.

The book provides a rich set of case study material that deepens our understanding of the experiences of disabled people and challenges students, researchers, and practitioners to reflect critically upon their own positionality. The first part of the book discusses the ways in which disability has been conceptualized, how the voices of disabled people have sometimes been marginalized, and how nondisability power has historically framed the narratives of disabled people in physical …


Forests And Cycles Of Agrarian Sustenance: Time-To-Event Analysis Of Ecosystem Provisioning Services And Seasonal Food Insecurity, Kamaldeen Mohammed, Daniel Kpienbaareh Apr 2025

Forests And Cycles Of Agrarian Sustenance: Time-To-Event Analysis Of Ecosystem Provisioning Services And Seasonal Food Insecurity, Kamaldeen Mohammed, Daniel Kpienbaareh

Faculty Publications - Geography, Geology, and the Environment

In Savanna ecosystems, cycles of sustenance include periods of food abundance and deficits. In rain-fed agricultural systems, forests are a vital food source that helps households close this cycle. This paper uses cross-sectional data to explore the association between provisioning ecosystem services and timing to food insecurity in forest fringe communities (N = 500). The time to food insecurity analysis revealed a significant difference in the onset of food insecurity among households with varying levels of access to forest provisioning services. Households with access to more than four forest products experienced a slower timing to seasonal insecurity. In contrast, …


Validation Of Digirop- Birth And Digirop- Screen For The Discovery Of Retinopathy Of Prematurity Requiring Treatment In Preterm Births In Saudi Arabia, Huda K. Ahmedhussain, Lina H. Raffa, Amal M. Alosaimif, Sarah K. Alessa, Suzan Y. Alharbi, Hashem Almarzouki, Mansour A. Alqurashi Apr 2025

Validation Of Digirop- Birth And Digirop- Screen For The Discovery Of Retinopathy Of Prematurity Requiring Treatment In Preterm Births In Saudi Arabia, Huda K. Ahmedhussain, Lina H. Raffa, Amal M. Alosaimif, Sarah K. Alessa, Suzan Y. Alharbi, Hashem Almarzouki, Mansour A. Alqurashi

Saudi Medical Journal

ABSTRACT Objectives: To validate 2 DIGIROP prediction models for retinopathy of prematurity (ROP) type 1 and compare them to other weight-based algorithms in a premature Saudi Arabian infant cohort. Methods: Preterm infants of 24-30 weeks’ gestational age (GA) or body weight (BW) of ≤1500g who were admitted to the neonatal units of 2 Jeddah tertiary centers between January 2015 and September 2021 were included (N=363). The DIGIROP-Birth employed the birth GA, gender, birth weight, and age at ROP onset as predictors. The area under the receiver operating characteristic curve (AUC) with 95% confidence interval, specificity, and sensitivity were projected. The …


The Short-Term Effects Of Fluctuating Sleep Timing On Cardiovascular And Metabolic Health, Gabe Dennett Apr 2025

The Short-Term Effects Of Fluctuating Sleep Timing On Cardiovascular And Metabolic Health, Gabe Dennett

Inquiry Journal Spring 2025

This study investigates the short-term effects of an acute circadian fluctuation protocol on the cardiovascular and metabolic health of young recreationally active college students. While the deleterious effects of sleep deprivation on a person’s health are wide reaching and well established, circadian misalignment—the discrepancy between biological clocks and external cues—remain under investigated. This research highlights “social jet lag,” a common phenomenon among young people wherein inconsistent sleep and wake times driven by social, school, work, or other commitments creates irregularity in hormonal rhythms, autonomic, and metabolic processes; emphasizing the emerging recognition that not just how much we sleep, but when …


Graduate Studies Newsletter (Spring 2025), Csusb - Office Of Graduate Studies Apr 2025

Graduate Studies Newsletter (Spring 2025), Csusb - Office Of Graduate Studies

Graduate Studies Newsletter

No abstract provided.


Mashed Potato Gravy Boat And Cream Cheese Fish: Modifying A 3d Printer To Print With Unconventional Materials, Aahanaa Tibrewal Apr 2025

Mashed Potato Gravy Boat And Cream Cheese Fish: Modifying A 3d Printer To Print With Unconventional Materials, Aahanaa Tibrewal

Mathematics, Statistics, and Computer Science Honors Projects

3D printing is growing beyond plastics into fields like food and construction, bringing rapid additive manufacturing to various industries and consumers. However, high costs and the need for specialized knowledge limit access for many. My project aimed to modify a low-cost 3D printer to print with paste-like materials using commonly available parts and simple processes. I tested the modification with clay, mashed potatoes, and cream cheese, and found that it successfully worked with all three. This modification has three key benefits: it allows users to print with unconventional materials, helps researchers create low-cost proof of concepts, and contributes to the …


Ibuprofen, Flurbiprofen Or Naproxen Sodium Minimally Influences Musculoskeletal Adaptations To Treadmill Exercise In Rats, Brandon Roberts, Alyssa Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa Varanoske, Alyssa Kelley, Maximus Leiss, Alexander Kolb, Julie Hughes, Marshall Naimo, Ryan Tomlinson, Jeffery Staab Apr 2025

Ibuprofen, Flurbiprofen Or Naproxen Sodium Minimally Influences Musculoskeletal Adaptations To Treadmill Exercise In Rats, Brandon Roberts, Alyssa Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa Varanoske, Alyssa Kelley, Maximus Leiss, Alexander Kolb, Julie Hughes, Marshall Naimo, Ryan Tomlinson, Jeffery Staab

Department of Orthopaedic Surgery Faculty Papers

BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) may influence musculoskeletal health. The purpose of this study was to compare the effects of three different NSAIDS: naproxen sodium, ibuprofen, flurbiprofen or a placebo on musculoskeletal adaptations in rodents with or without 6 weeks of aerobic exercise.

METHODS: Nine-week-old male Wistar rats (n = 80) were randomized to either exercise (EX) or no-exercise control (CON) conditions and treated with naproxen, ibuprofen (IBU), flurbiprofen (FLU) or placebo (PLA). For exercise, rats ran 5 days per week for 6 weeks at a 5% incline on a motorized treadmill for 30 min. Three-point bending (3 PB) and …


Assessment Of Plasma D-Dimer Level In Patients With Acute Ischemic Stroke, Ali Raheem, Aqeel Hatem Aljaberi Apr 2025

Assessment Of Plasma D-Dimer Level In Patients With Acute Ischemic Stroke, Ali Raheem, Aqeel Hatem Aljaberi

Iraqi Postgraduate Medical Journal

Background: Stroke is defined as "rapidly clinical symptoms of focal (or global) impairment of brain function, lasting longer than 24 hours or leading to death, with vascular origin " according to the World Health Organization. It has been suggested that elevated circulating D-dimer molecule is formed when plasmin digests the fibrin clot. Values may be associated with acute ischemic stroke (AIS). Aim: to estimate the level of plasma D-dimer in acute ischemic stroke patients and to study the effect of sociodemographic data on the level of D-dimer.Method: It's a cross-sectional study of 300 participants of whom 200 were with acute …


Building Trustable Methods For Group Recommendations: Advancing Fairness And Robustness Across Domains, Siva Likitha Valluru Apr 2025

Building Trustable Methods For Group Recommendations: Advancing Fairness And Robustness Across Domains, Siva Likitha Valluru

Theses and Dissertations

On the internet, where the number of available choices for information is exponentially growing, there is a need to prioritize and deliver relevant results to users efficiently, on demand. Recommendation systems (RSs) address that need by searching through and filtering large amounts of dynamically generated information and providing users with recommendations tailored to them. These systems have primarily focused on (1) single-user models, where recommendations are tailored towards a specific individual, or (2) single-item models, where items are recommended based on a broader appeal to users and similarities in item metadata, in the past. In many real-world scenarios, however, recommendation …


Phytochemicals And Human Health, Erin Kelley Richards Apr 2025

Phytochemicals And Human Health, Erin Kelley Richards

Theses and Dissertations

This review explores the intricate relationship between phytochemical intake and human health. It first highlights the contrast between the phytochemical-poor Standard American Diet (SAD) and ancestral diets rich in diverse plant and animal foods. The classification, sources, and health benefits of various phytochemicals, including polyphenols, flavonoids, alkaloids, and terpenes are described and discussed. The bioavailability of these compounds and their interactions with the gut microbiome are elucidated, emphasizing on their potential in modulating multiple pathways associated with aging and chronic diseases. The 12 hallmarks of aging and how phytochemicals may influence these hallmarks are reviewed. While exploring the potential benefits …


The Association Between Parent’S Mobile Device Use And Physical Activity, Sydney Hill Apr 2025

The Association Between Parent’S Mobile Device Use And Physical Activity, Sydney Hill

Theses and Dissertations

Background. The rapid increase in mobile technology has allowed smartphones to be used almost anywhere, but a potential disadvantage of these mobile devices is the displacement of physical activity. Parents of young children are already struggling to reach higher intensities of physical activity and mobile devices might make this worse. However, most existing research on similar topics look at adults without children or uses subjective measures only. Therefore, this study aims to (1) quantify objective mobile device use from a sample of parents with preschool age children; (2) describe the duration and intensity of parents’ physical activity and inactive behavior; …


Fnes 203: Meal Planning And Therapeutic Diets, Patrick J. Moran Jr Apr 2025

Fnes 203: Meal Planning And Therapeutic Diets, Patrick J. Moran Jr

Open Educational Resources

Application of principles of meal planning to evidence-based therapeutic diets. Lecture and laboratory include menu planning, food cost analysis, therapeutic modifications to recipes, preparation, and service of food in accordance with food safety principles, and effective time management, collaboration, and teamwork in the food production facilities.


Culture And Sustainability: Understanding The Roles Of Values, Norms, And Cultural Tightness In Sustainable Consumption Behaviour, Sook Sum Au Apr 2025

Culture And Sustainability: Understanding The Roles Of Values, Norms, And Cultural Tightness In Sustainable Consumption Behaviour, Sook Sum Au

Dissertations and Theses Collection (Open Access)

The past decade has seen an increased interest in environmental sustainability. Yet, few studies have examined the relationship between culture, sustainable consumption intention (SCI), and sustainable consumption behaviour (SCB). This study addresses this gap by examining the roles of values, norms and CTL in an integrative model to predict SCI and SCB. This study focuses on four types of values that are considered most relevant in environmental research (biospheric, altruistic, egoistic, and hedonic). Drawing on data from a sample across the 10 most culturally "tight" and 10 most culturally "loose" states in the US, this study applied multilevel modelling to …


Dizziness And Vertigo Ambulatory, Children's Mercy Kansas City Apr 2025

Dizziness And Vertigo Ambulatory, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


Suspected Abusive Head Trauma, Children's Mercy Kansas City Apr 2025

Suspected Abusive Head Trauma, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


Adipocyte-Derived Cchamide-1, Eiger, Growth-Blocking Peptide 3, And Unpaired 2 Regulate Drosophila Melanogaster Oogenesis, Chad Simmons, Isaiah H. Williams, Tancia W. Bradshaw, Alissa R. Armstrong Apr 2025

Adipocyte-Derived Cchamide-1, Eiger, Growth-Blocking Peptide 3, And Unpaired 2 Regulate Drosophila Melanogaster Oogenesis, Chad Simmons, Isaiah H. Williams, Tancia W. Bradshaw, Alissa R. Armstrong

Faculty Publications

In addition to energy storage, adipose tissue communication to other organs plays a key role in regulating organismal physiology. While the link between adipose tissue dysfunction and pathophysiology, including diabetes, chronic inflammation, and infertility, is clear, the molecular mechanisms that underlie these associations have not been fully described. We use Drosophila melanogaster as a model to better understand how adipose tissue communicates to the ovary. In this study, we utilized D. melanogaster’s robust genetic toolkit to examine the role of five adipokines known to control larval growth during development, CCHamide-1, CCHamide-2, eiger, Growth-blocking peptide 3, and unpaired 2 in regulating …


Alumni Journal - Volume 96, Number 1, Loma Linda University School Of Medicine Apr 2025

Alumni Journal - Volume 96, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
7 | This & That
10 | Alumni News
12 | School of Medicine News
14 | AIMS Report: Short-term Mission, Long-term Impact
16 | Student Appreciation
18 | Department Report: Preventative Medicine

APC 2025
20 | Annual Postgraduate Convention (APC) 2025 in Review

Features
34 | Building Connections
36 | Divine Connections
38 | Remembering Ath 'AT' Tuot
42 | Alumni Spotlight: Featuring Janet T. Strausbaugh '78-A
44 | Life After Medicine

In Memoriam
45 | Alumni Remembered: Featured Obituaries: David Tse …


N Y State Dent J April 2025 Apr 2025

N Y State Dent J April 2025

The New York State Dental Journal

In the April 2025 issue, the reader will find the following feature articles:

  • Treatment Options for Pre-eruptive Intracoronal Resorption of Permanent Teeth: A Report of Two Cases
  • Successful Treatment of a “Pedo-Endo” Lesion in a Primary First Molar
  • Comparison of Untreated Caries and Caries-Risk Improvement in an Elementary-School-Based Comprehensive Dental Care Program

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.


Quality-Of-Care Measures For Cardio-Oncology: An Ic-Os And Acc Cardio-Oncology Leadership Council Perspective, Vijay U Rao, Anita Deswal, Daniel Lenihan, Susan Dent, Teresa Lopez-Fernandez, Alexander R Lyon, Ana Barac, Nicolas Palaskas, Ming Hui Chen, Hector R Villarraga, Diego Sadler, Courtney M Campbell, Kerry Skurka, Matt J Wagner, Matthias Totzeck, Kathryn J Ruddy, Paul Heidenreich, Randal Thomas, Daniel Addison, Sarju Ganatra, Richard Cheng, David Reeves, Arjun K Ghosh, Joerg Herrmann Apr 2025

Quality-Of-Care Measures For Cardio-Oncology: An Ic-Os And Acc Cardio-Oncology Leadership Council Perspective, Vijay U Rao, Anita Deswal, Daniel Lenihan, Susan Dent, Teresa Lopez-Fernandez, Alexander R Lyon, Ana Barac, Nicolas Palaskas, Ming Hui Chen, Hector R Villarraga, Diego Sadler, Courtney M Campbell, Kerry Skurka, Matt J Wagner, Matthias Totzeck, Kathryn J Ruddy, Paul Heidenreich, Randal Thomas, Daniel Addison, Sarju Ganatra, Richard Cheng, David Reeves, Arjun K Ghosh, Joerg Herrmann

Children’s Nutrition Research Center Staff Publications

This document serves as a perspective on quality assessments in the discipline of cardio-oncology. We aim to define the current landscape, identify needs for quality and outcome improvements, and propose a roadmap for establishing viable metrics to improve patient care. Specifically, this document: 1) addresses the current lack of measurable high-quality metrics in cardio-oncology and their implications; 2) highlights needs and topic-specific barriers; 3) illustrates the process and application of a measurable quality metric; and 4) provides a framework to demonstrate measurable value for the growing population of patients with cancer and cardiovascular diseases.


Demographic Clinical Trial Diversity Assessment Methods: Use Of Real-World Data, Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford Apr 2025

Demographic Clinical Trial Diversity Assessment Methods: Use Of Real-World Data, Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford

Children’s Nutrition Research Center Staff Publications

Diversity in clinical trials is defined by the inclusion of clinical trial participants from various demographic groups that are representative of the broader population impacted by a disease state. Diversity in clinical trials is critical in identifying potential differences in safety and efficacy of treatments across races, ethnicities, ages, sexes, or other variables. In the United States, clinical trial diversity is often benchmarked against US Census data, which may limit the representativeness of patient demographics in clinical trials. Disease-specific, demographic estimates from real-world data (RWD) can facilitate benchmarking of clinical trials, support trial enrollment and the development of trial diversity …


Therapeutic Role Of Bioactive Peptides Derived From Hemoglobin, Priya Antony Pereppadan Apr 2025

Therapeutic Role Of Bioactive Peptides Derived From Hemoglobin, Priya Antony Pereppadan

Dissertations

Bioactive peptides are peptide fragments derived from the proteolytic cleavage or maturation of functional proteins that have shown promising therapeutic potential in addressing major health challenges, including type 2 diabetes, hypertension, and pain management. Diabetes is characterized by high blood glucose levels due to insufficient insulin production or utilization. There are several therapeutic targets for managing diabetes, and one key target is dipeptidyl peptidase IV (DPP IV) due to its role in glucose metabolism. In hypertension, angiotensin-converting enzyme 1 (ACE1) is critical for regulating blood pressure by forming angiotensin II, and its inhibition represents an established treatment strategy. Additionally, the …