Digital Commons Network^™

The Impact Of Different Antidiabetic Drugs On Fracture Risk In Patients With Type 2 Diabetes Mellitus: A Systematic Review And Network Meta-Analysis Of Randomized Controlled Trials With A Focus On Sglt2 Inhibitors, Bushra Admani, Fizza Z. Raza, Fatima Siddiqui, Muhammad T. Ashraf, Muhammad K. Khan, Ifra Habib, Ayesha Usman, Bareeha Mansoor, Zaira Nadeem, Rana J. Ghaffer, Muhammad Riyyan, Sawaira Sajid, Muhammad H. A. Chania, Mahnoor Saleem, Saad Javaid, Nikhil Duseja, Hussam Al Hennawi, Sunita Lakhani

Abington Jefferson Health Papers

SGLT2 inhibitors are a new class of antidiabetic drugs that have shown cardiovascular benefits in patients with type 2 diabetes mellitus (T2DM) and cardiovascular disease. However, their effects on fracture risk are unclear and may depend on the type and duration of treatment. This meta-analysis compares the fracture risk of different antidiabetic drugs, including SGLT2 inhibitors, based on data from randomized controlled trials (RCTs). We searched 4 databases for RCTs that reported fracture events in patients with T2DM who received different antidiabetic drugs. We included 117 RCTs that compared 9 types of antidiabetic drugs: SGLT2 inhibitors, DPP-4 inhibitors, α-glucosidase inhibitors, …

Association Of Obesity And Body Mass Index Classification With Glycemic Control In Adults Who Are Critically Ill Receiving Parenteral Nutrition: A Retrospective Study., Erika L Mackie, Melissa Dang, Kimberly Sharpe, Justin Delic, James M Hollands, Song Oh, Stacy Pasciolla, Laura Pontiggia, Diana Solomon, Angela Bingham

Ambulatory and Primary Care Articles

BACKGROUND: Hyperglycemia is a complication of parenteral nutrition (PN), which can be exacerbated in patients with obesity. Limited data exist on glycemic control in this population. This study aims to evaluate the association of obesity and body mass index (BMI) classification with glycemic control in patients who are critically ill initiated receiving PN.

METHODS: This is a retrospective study of patients who are critically ill receiving PN from January 2013 to February 2024. The primary outcome was glycemic control in patients with BMI ≥ 30 kg/m

RESULTS: The study included 220 patients with BMI ≥ 30 kg/m

CONCLUSION: Patients who …

Use Of Cigarettes, Cannabis, And Alcohol Among Asian American, Native Hawaiian, And Pacific Islander Adults: Community-Based National Survey Analysis, Vuong Van Do, Van My Ta Park, Nhung Nguyen, Pamela May Ling, Marian Tzuang, Bora Nam, Marcelle M. Dougan, Oanh L. Meyer, Janice Y. Tsoh

Faculty Research, Scholarly, and Creative Activity

Background: Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations have diverse cultural, immigra-tion, and sociodemographic characteristics. Aggregated data could mask substantial differences in substance use between cultural subgroups in this population. Yet, studies examining substance use among the AANHPI population are limited. Objective: This study aimed to describe cigarette, cannabis, and alcohol use among AANHPI adults by cultural subgroup and sex. Methods: We analyzed data from 3411 AANHPI respondents of a multilingual national survey “COMPASS” during December 2021-May 2022. Primary outcomes were self-report current (every day or some days) use of cigarettes, cannabis, and alcohol. Cultural subgroups included Asian …

Enhanced Recovery After Surgery (Eras) Protocol, Jennifer Smith

Group: Nebraska Methodist College

Problem: Enhanced Recovery After Surgery (ERAS) protocols aim to minimize surgical stress, improve patient outcomes, and shorten hospital stays. While ERAS has shown benefits in various surgical disciplines, challenges were faced in implementing and customizing these protocols for specific populations. This project evaluated how ERAS interventions impact recovery metrics, including hospital length of stay, bowel recovery, and cardiac rehabilitation outcomes.

Intervention: ERAS-based perioperative care strategies were implemented focusing on early mobilization, optimized pain management, reduced opioid use, and timely enteral nutrition. The patients were monitored for compliance and adherence to protocol components to assess their effect on recovery.

Measures: Primary …

Beyond The Bottle: The Lifelong Consequences Of Fetal Alcohol Spectrum Disroder, Victoria M. Van Curen Ms.

Master of Arts in Human Services

With increasing numbers of Fetal Alcohol Spectrum Disorder, the focus is on FASD and the impact it has on mothers’, their unborn child, and the consequences that will lead to long-lasting effects. Once women find out that they are expecting, they stop drinking alcohol, but there is still statistic that shows about 8% of women reported that they continue to consume alcohol during their pregnancy. The paper will also include multiple real-life examples of studies that have been conducted on individuals with FASD. With studies focusing on individuals with FASD, it will also include different populations with FASD, and the …

Use Of A Novel Plant Essential Oil-Based Insecticide For Insect Control In Household Gardens And Lawns, Mia Michnik, Alysa Suissa, Liah Brussolo Cremona, Annalise Wellman, Nicholas Nifakos, Alexander Spanoudis, John M. Harlin

Florida Atlantic Undergraduate Research Journal

Insecticide use has increased as population and agricultural demand for crops grows. Commercial insecticides contain active ingredients that are often harmful to humans and the environment. A viable alternative to this concern is developing and using insecticides with low toxicity and minimum risk to the environment. In this study, we sought to empirically assess the effectiveness of an insecticide based entirely on plant essential oil active ingredients, which contain complex secondary metabolites. Our results show that a concoction of several plant essential oils was effective in killing a wide range of household garden insect species and bedbugs, encompassing five orders …

Diagnosing And Testing Gi Motility, Michael Smith, Sofia Colon Guzman

Pediatrics in Practice: A CME Podcast

We dive into the most common pediatric GI motility disorders, when to refer for testing, and how to navigate diagnostics like manometry and gastric emptying studies. Learn how to approach testing in non-verbal children, distinguish functional from structural issues, and stay updated on emerging tools in the field.

Click here to stream the podcast episode.

Educating Nurses On The Agency Of Healthcare Research And Quality Pressure Ulcer Prevention Program To Reduce The Rate Of Pressure Ulcers, Marie France Destaul

Walden Dissertations and Doctoral Studies

A staff development project was conducted to address the practice problem encountered in a healthcare setting. The identified gap in practice was related to a lack of knowledge of pressure ulcer injury prevention among inpatient staff. Leadership deemed it essential to address this practice problem in nursing care because the prevalence of pressure ulcer injuries in hospitalized patients was high. The following practice-focused question guided the project: For staff in an inpatient setting, will education on the Agency of Healthcare Research and Quality (AHRQ) Pressure Ulcer Prevention Program increase knowledge toward the goal of decreasing the incidence of pressure ulcers? …

Bronchopulmonary Dysplasia Diagnosis And Screening, Bob Underwood, Winston Manimtim

Pediatrics in Practice: A CME Podcast

Winston Manimtim, MD, discusses bronchopulmonary dysplasia including affects and complications, provides guidance to pediatricians working with patients with BDP and more in this episode.

Click here to stream the podcast episode.

Causes Of Symptoms And Symptom Persistence In Long Covid And Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Anthony L Komaroff, Robert Dantzer

Faculty, Staff and Student Publications

Debilitating symptoms for many years can follow acute COVID-19 ("long COVID"), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and various post-acute infection syndromes (PAISs). Together, long COVID and ME/CFS affect 60-400 million individuals, globally. Many similar underlying biological abnormalities have been identified in both conditions including autoantibodies against neural targets, endothelial dysfunction, acquired mitochondrial dysfunction, and a pro-inflammatory gut microbiome. Each of these abnormalities may directly cause some of the symptoms. In addition, the symptoms also may be caused by ancient, evolutionarily conserved symptomatic and metabolic responses to vital threats-sickness behavior and torpor-responses mediated by specific, recently discovered neural circuits. These neural …

Dna Methylation Signatures Of Cardiovascular Health Provide Insights Into Diseases, Madeleine Carbonneau, Yi Li, Yishu Qu, Yinan Zheng, Alexis C Wood, Mengyao Wang, Chunyu Liu, Tianxiao Huan, Roby Joehanes, Xiuqing Guo, Jie Yao, Kent D Taylor, Russell P Tracy, Peter Durda, Yongmei Liu, W Craig Johnson, Wendy S Post, Tom Blackwell, Jerome I Rotter, Stephen S Rich, Susan Redline, Myriam Fornage, Jun Wang, Hongyan Ning, Lifang Hou, Donald Lloyd-Jones, Kendra Ferrier, Yuan-I Min, April P Carson, Laura M Raffield, Alexander Teumer, Hans J Grabe, Henry Völzke, Matthias Nauck, Marcus Dörr, Arce Domingo-Relloso, Amanda Fretts, Maria Tellez-Plaza, Shelley A Cole, Ana Navas-Acien, Meng Wang, Joanne M Murabito, Nancy L Heard-Costa, Brenton Prescott, Vanessa Xanthakis, Dariush Mozaffarian, Daniel Levy, Jiantao Ma

Faculty, Staff and Students Publications

Background: The association of overall cardiovascular health (CVH) with changes in DNA methylation (DNAm) has not been well characterized.

Methods: We calculated the American Heart Association's Life's Essential 8 score to reflect CVH in 5 cohorts with diverse backgrounds (mean age 54 years, 55% women, and enrollment year ranging from 1989 to 2012). Epigenome-wide association studies (EWAS) for Life's Essential 8 score were conducted, followed by bioinformatic analyses. DNAm loci significantly associated with Life's Essential 8 score were used to calculate a CVH DNAm score. We examined the association of the CVH DNAm score with incident cardiovascular disease (CVD), cardiovascular …

Changes In Self-Reported Excessive Daytime Sleepiness Are Associated With 5-Year All-Cause Mortality Risk Among Veterans, Katherine G Bay, Arash Maghsoudi, Amin Ramezani, Drew A Helmer, Amir Sharafkhaneh, Javad Razjouyan

Faculty, Staff and Students Publications

Excessive daytime sleepiness (EDS) is linked to adverse clinical outcomes. This study evaluated changes in a validated tool to assess EDS, the Epworth Sleepiness Scale (ESS) and mortality risk. This retrospective cohort study included Veterans receiving sleep-related services in the Department of Veterans Affairs (VA) from October 4, 1999 to August 18, 2018, with two qualifying ESS measures. ESS values were extracted from patient notes using a validated natural language processing (NLP) pipeline (96% accuracy). ESS scores were categorised as Normal (0-10) or Abnormal (11-24). Patients were grouped based on ESS changes: Normal-Normal, Normal-Abnormal, Abnormal-Abnormal and Abnormal-Normal. Cox proportional hazards …

Exploring Neuropsychiatric Manifestations Of Vitamin B Complex Deficiencies, Anamaria Han, Leandro Almeida, Nikhilesh Anand, Ihsan Salloum, Salim Kanaan, Bharathi Gadad, João Paulo Lima Daher

School of Medicine Publications

B complex vitamins, a group of eight water-soluble vitamins, play interconnected roles in maintaining nervous system health. Thiamine (B1), riboflavin (B2), and niacin (B3) are essential as co-enzymes in numerous metabolic reactions related to energy production. Thiamine is involved in the Krebs cycle, riboflavin in the electron transport chain, and niacin plays a key role in both glycolysis and the Krebs cycle. These metabolic processes are vital for sustaining the integrity of the nervous system, as the energy produced is critical for the functioning of nerve cells. Deficiencies in these vitamins can lead to significant neurological and psychiatric conditions, including …

Validity And Reliability Of The 'Feelfit®' Accelerometer In Evaluating Physical Activity And Sedentary Time In Children: A Comparative Study With Two Different Accelerometers, Songdhasn Chinapong, Korntawat Klinchan, Hanif Abdul Rahman, Michael Chia, Waris Wongpipit, Jetsada Arnin, Areekul Amornsriwatanakul

International Journal of Exercise Science

International Journal of Exercise Science 18(2): 794-810, 2025. Accurate physical activity (PA) measurement is crucial for public health surveillance. While self-report questionnaires are commonly used, they have limitations, especially in young children. An affordable and user-friendly device like Feelfit® offers a promising alternative particularly for countries with limited research resources. This study aimed to evaluate Feelfit®’s performance against the widely used ActiGraph® accelerometer in measuring PA among children. A quasi-experimental design was applied. Thirty-nine children (19 boys; 20 girls; aged 11.4 ± 0.5 years) wore both Feelfit® and ActiGraph® during sequentially specified activities of varying intensity ranging from sedentary to …

The Shorthorn: April 28, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 27, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 19, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: April 12, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 17, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 16, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: March 11, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: February 22, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: January 26, 1977

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: November 10, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: October 1, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 21, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 14, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 9, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 3, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.

The Shorthorn: September 8, 1976

The Shorthorn Newspaper Collection: 1970s

No abstract provided.