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Articles 571 - 600 of 36916
Full-Text Articles in Entire DC Network
Seth Matlick, Seth Matlick, Erin Elder
Seth Matlick, Seth Matlick, Erin Elder
Oral Histories of Farming along the Middle Rio Grande
No abstract provided.
Design Of An Fsae Muffler, Suzy Schwabl
Design Of An Fsae Muffler, Suzy Schwabl
Mechanical Engineering and Materials Science Independent Study
To compete in the dynamic events at the the Formula SAE IC competition, each vehicle must undergo a rigorous technical inspection. One element of the inspection is the Noise Test, which states that each car must be quieter than 103 dBc when idling and less than 110 dBc at the engine redline. Over the past few years, WashU Racing has used off-the-shelf mufflers with a guess and check system to find muffler combinations that satisfy the noise requirement. The results of that method have yielded either heavy and performance damaging muffler configurations or mufflers that have failed to meet the …
Unintended Consequences Of California’S Proposition 12 Affecting Low-Income Communities, Blanca Estella Garcia
Unintended Consequences Of California’S Proposition 12 Affecting Low-Income Communities, Blanca Estella Garcia
Walden Dissertations and Doctoral Studies
The background of this study established context describing the 2018 implementation of Proposition 12 in California, a law intended to improve animal welfare standards. The central problem identified the law’s unintended effects on multiple stakeholders, which prior literature suggested could include increased production costs and limit consumer access. However, existing studies have focused on theoretical and economic projections, leaving gaps in understanding secondary data research and practical impacts on farmers and low-income consumers. The purpose of the study was to examine unforeseen consequences of Proposition 12, with attention to its direct and indirect impacts on animal welfare, farmers, and low-income …
Reimagining A Nexus Between Seaport And National Development: Sociotechnical Imaginaries Of Ghana’S Port Of Tema, Jonas Aryee, Casper Andersen, Annette Hansen
Reimagining A Nexus Between Seaport And National Development: Sociotechnical Imaginaries Of Ghana’S Port Of Tema, Jonas Aryee, Casper Andersen, Annette Hansen
Plymouth Business School
This article explores the evolving sociotechnical imaginaries (STIs) shaping Ghana’s Port of Tema, revealing how national development goals and global trade imperatives intersect in African port governance. Through analysis of policy documents, media discourse, and interviews, it identifies four overlapping phases in the evolution of these imaginaries: the industrial gateway era, neoliberal globalization, the rise of a transshipment hub, and the most recent phase of indigenous contestation and institutional resilience. Rather than replacing earlier visions, newer imaginaries build upon and hybridize older ones, creating both synergies and tensions. The study demonstrates that STIs at Tema have evolved through processes of …
Enhanced Oviposition Preferences And Larval Performance Of Hermetia Illucens L. In Fruit Wastes Fermented By Effective Microorganisms, Resti Rahayu, Robby Jannatan, Muhamad Ronaldo, Risa Ukhti Muslima
Enhanced Oviposition Preferences And Larval Performance Of Hermetia Illucens L. In Fruit Wastes Fermented By Effective Microorganisms, Resti Rahayu, Robby Jannatan, Muhamad Ronaldo, Risa Ukhti Muslima
Makara Journal of Science
Organic waste comprises a considerable portion of global waste, requiring effective management. The ability of the black soldier fly (Hermetia illucens, BSF) to convert organic waste into biomass has been well reported. However, bioconversion can be hindered by fiber-rich substrates, a challenge that can be addressed through substrate pretreatment. This study examined the oviposition preferences and larval performance of BSFs in several fruit wastes fermented by effective microorganisms (EMs), which were compared to non-fermented substrates. The oviposition attractants utilized pineapple peel and overripe soursop, with larval performance evaluated among different treatments, i.e., non-fermented pineapple peel (NFP), fermented pineapple …
Fast Dispersion-Curve Inversion Using Automatic Differentiation Gradient-Based Calculation, Theodosius Marwan Irnaka, Eddy Hartantyo
Fast Dispersion-Curve Inversion Using Automatic Differentiation Gradient-Based Calculation, Theodosius Marwan Irnaka, Eddy Hartantyo
Makara Journal of Science
Surface wave inversion is a crucial technique in geophysics for subsurface imaging. However, traditional methods can be computationally intensive, especially for complex models. This study introduces automatic differentiation (AD) as an efficient alternative to finite difference (FD) methods for gradient calculation in surface wave inversion. We compare AD and FD methods using three synthetic examples of varying complexity. Our results demonstrate that AD is significantly faster, with speed improvements of 3 to 12 times over FD, depending on model complexity. Moreover, AD requires up to 3 times less memory than FD. In terms of accuracy, AD provides gradient calculations that …
Perspectives On The Future Of The Profession Of Microbiology, Todd L Kelson, Heidi B Kaplan, Michelle Dziejman, Shilpa Gadwal, Irene Hulede, Jennifer Bennett, Roger Greenwell, Shelley Payne, Kyle Maclea, Eric Miller, Diana L Vullo, Rebecca Sparks-Thissen, Astral Bertolio, Jorge Cervantes
Perspectives On The Future Of The Profession Of Microbiology, Todd L Kelson, Heidi B Kaplan, Michelle Dziejman, Shilpa Gadwal, Irene Hulede, Jennifer Bennett, Roger Greenwell, Shelley Payne, Kyle Maclea, Eric Miller, Diana L Vullo, Rebecca Sparks-Thissen, Astral Bertolio, Jorge Cervantes
Faculty, Staff and Student Publications
The Profession of Microbiology (POM) embodies the bulk of the American Society for Microbiology (ASM) members and represents the career preparation arm of the ASM for academia, industry, and clinical lab professions. The ASM Council on Microbial Sciences hosted a virtual retreat in 2025 to identify the future of the POM. The retreat presentations centered on workforce development, professional development, innovations in technology, and interdisciplinary collaborations. Various aspects were identified, such as the need to prepare for careers in industry, as an important goal of future training. It was also clear that scientists, in all walks of life, need professional …
Eif3d And Eif3e Mediate Selective Translational Control Of Hypoxia That Can Be Inhibited By Small Molecules, Stephen C Purdy, Kate Matlin, Christopher Alderman, Amber Baldwin, Natasha Shrivastava, Goksu Sarioglu, Somnath Dutta, Kristofor J Webb, Arthur Wolin, Dillon P Boulton, Annika Gustafson, Jyoti Kapali, John D Landua, Michael T Lewis, M Cecilia Caino, James C Costello, William Old, Xiang Wang, Rui Zhao, Heide L Ford, Neelanjan Mukherjee
Eif3d And Eif3e Mediate Selective Translational Control Of Hypoxia That Can Be Inhibited By Small Molecules, Stephen C Purdy, Kate Matlin, Christopher Alderman, Amber Baldwin, Natasha Shrivastava, Goksu Sarioglu, Somnath Dutta, Kristofor J Webb, Arthur Wolin, Dillon P Boulton, Annika Gustafson, Jyoti Kapali, John D Landua, Michael T Lewis, M Cecilia Caino, James C Costello, William Old, Xiang Wang, Rui Zhao, Heide L Ford, Neelanjan Mukherjee
Faculty, Staff and Students Publications
Exposure to hypoxia is linked to increased cellular plasticity and enhanced metastasis, effects that are primarily attributed to the transcriptional activation of large gene programs downstream of hypoxia-inducible factors (HIFs). However, translational effects in hypoxia, which likely precede transcriptional effects, have remained largely unexplored. Using ribosome profiling, we uncovered a selective translational response in acute hypoxia that is eukaryotic initiation factor (eIF)3d/eIF3e dependent and controls downstream hypoxic responses, including HIF1α accumulation and cellular invasion. We further demonstrated that eIF3e copy number and eIF3e and eIF3d expression signatures are associated with worsened outcomes for patients with breast cancer. Finally, we identified …
Despair Amongst Brazil’S Youth: Does The Hague Convention On International Child Abduction Need More Bite?, Ishani Sanyal
Despair Amongst Brazil’S Youth: Does The Hague Convention On International Child Abduction Need More Bite?, Ishani Sanyal
Pace International Law Review
For decades, international child abduction by one parent from the legal custody of the other has been a persistent issue which continues to be overlooked by international organizations and countries from around the world. While the Hague Convention on the Civil Aspects of International Child Abduction has helped to initiate certain progress in addressing acts of international child abduction by parents, signatory states including Brazil have failed to enforce rulings and provisions of the convention. This article addresses how the convention does not account for structural inadequacies of Brazilian court systems which prevent thorough enforcement of international custody and visitation …
Conserving Conservation Servitudes: The Role Of The Prior Public Use Doctrine In Protecting Privately Conserved Land In The United States And Australia, Olivia Clausen
Pace International Law Review
Both the United States and Australia would benefit from more conservation of private land, and conservation servitudes can help both countries achieve this. However, in the United States and Australia, the power of eminent domain is a threat to the perpetuity of conservation servitudes. The prior public use doctrine, a common law doctrine in the United States arising out of the public trust doctrine, could limit eminent domain in these cases and provide protection to conservation servitudes. This doctrine states that land devoted to one public use (such as conservation) may not be condemned for another inconsistent public use unless …
Rightly Dividing Jus Ad Bellum And Jus In Bello In The Israel/Hamas War, Jeffrey F. Addicott
Rightly Dividing Jus Ad Bellum And Jus In Bello In The Israel/Hamas War, Jeffrey F. Addicott
Pace International Law Review
No abstract provided.
A Crappy Job: Understanding Septic System Engagement In Rural Great Lakes Communities, Amanda Buday
A Crappy Job: Understanding Septic System Engagement In Rural Great Lakes Communities, Amanda Buday
Journal of Contemporary Water Research and Education
This study analyzes survey data from three eastern Lake Michigan watersheds to understand how rural homeowners engage in onsite wastewater treatment system (OWTS) maintenance. Responses about awareness and use of best management practices (BMPs), knowledge of system age, and barriers to recommended maintenance were used to develop a behavioral typology of homeowner engagement, with profiles ranging from proactive maintenance to passive noncompliance. This typology was then used to examine how management styles vary across geographic context, sociodemographic factors, and support for policy tools to promote proactive system care. While many homeowners report following recommended OWTS practices – even when facing …
An Analysis Of Fodmap Intake And Common Dietary Sources In The Irish Population, Sophie Ree, Farzana H. Ieha, Breige Mcnulty, Janette Walton, Suzanne L. Doyle
An Analysis Of Fodmap Intake And Common Dietary Sources In The Irish Population, Sophie Ree, Farzana H. Ieha, Breige Mcnulty, Janette Walton, Suzanne L. Doyle
SURE Journal: Science Undergraduate Research Experience Journal
Background/Objectives: Fermentable Oligosaccharides Disaccharides Monosaccharides and Polyols (FODMAPs) are a group of short chain carbohydrates that are poorly absorbed in the small intestine and can lead to gastrointestinal discomfort in sensitive individuals, particularly in those with irritable bowel syndrome (IBS). First-line treatment of IBS is a low FODMAP diet. However, little is known regarding FODMAP intake and the commonly consumed high FODMAP foods in the Irish population. This study aimed to investigate the FODMAP content of foods commonly consumed in the Irish diet.
Subjects/Methods: This study conducted a retrospective analysis of the 2011 National Adult Nutrition Survey (n=1500 adults, 4-day …
Concentration-Dependent Effects Of Green Tea Extract On The Growth And Metabolism Of Lacticaseibacillus Rhamnosus: An In Vitro Analysis, Jingxian Zeng, Francesco Noci, Kishor Keekan, Ulrich Hoeche
Concentration-Dependent Effects Of Green Tea Extract On The Growth And Metabolism Of Lacticaseibacillus Rhamnosus: An In Vitro Analysis, Jingxian Zeng, Francesco Noci, Kishor Keekan, Ulrich Hoeche
SURE Journal: Science Undergraduate Research Experience Journal
Green tea extract (GTE) is widely recognised for its bioactive compounds, which exhibit potential health benefits, including modulation of gut microbiota. However, the concentration-dependent effects of GTE on specific probiotic strains remain underexplored. The aim of this study was to systematically evaluate the concentration-dependent effects of green tea extract (GTE) on Lacticaseibacillus rhamnosus (L. rhamnosus). The promoting and inhibiting effects of GTE in the range of 0–50 mg/mL were analysed in vitro by OD₆₀₀ growth curve, pH change and colony forming unit (CFU) count. The experimental results showed that the concentration range of 0.05–2.05 mg/mL in the low concentration group …
The Influence Of Perceived Social Support On Mental Health During Injury In Female Gaa Athletes., Clodagh M. O’Connor, Samantha Glynn Kelly
The Influence Of Perceived Social Support On Mental Health During Injury In Female Gaa Athletes., Clodagh M. O’Connor, Samantha Glynn Kelly
SURE Journal: Science Undergraduate Research Experience Journal
Injury recovery in sport involves not only physical rehabilitation but also significant psychological challenges, particularly for female athletes in amateur and elite environments. This study aimed to explore the perceived social support received by injured female Gaelic Athletic Association (GAA) athletes and the effect it had on their mental health during injury. A qualitative research design was employed to gain an in-depth understanding of the experiences of injured female athletes. Data were collected through semi-structured, one-on-one interviews, allowing for open-ended responses and the exploration of individual perspectives. The sample consisted of 10 female athletes aged between 18 and 32 years, …
Developing A Tool To Measure Resistance To Sustainable Food Choices: A Pilot Study In Ireland And The Netherlands, Kate Flanagan, Bart Sinteur, Patricia J. Bulsing, John M. Kearney
Developing A Tool To Measure Resistance To Sustainable Food Choices: A Pilot Study In Ireland And The Netherlands, Kate Flanagan, Bart Sinteur, Patricia J. Bulsing, John M. Kearney
SURE Journal: Science Undergraduate Research Experience Journal
Consumer uptake of a sustainable diet is critical for addressing environmental challenges and promoting public health. Understanding why consumers resist adopting sustainable eating habits can inform targeted interventions and policies. This pilot study examines whether a newly developed scale can effectively detect consumer resistance to a sustainable diet. Currently, there is a lack of research on a tool to measure consumer resistance to a sustainable diet, highlighting the need for a reliable instrument.
The aim of this study is to develop a scale, based on existing literature, to measure consumer resistance to a sustainable diet. Additionally, the study aims to …
Innocent Until Proven Guilty, Disenfranchised All The Same: Hidden Voter Suppression Within American Jails, Kennedy Hill
Innocent Until Proven Guilty, Disenfranchised All The Same: Hidden Voter Suppression Within American Jails, Kennedy Hill
Arkansas Law Review
Jails throughout the United States hold thousands of legally eligible voters who have not been convicted of a crime While those convicted of felonies are often statutorily disenfranchised, pretrial detainees retain their civil rights—including the right to vote. In theory, this should guarantee them a voice. In practice, pretrial detention operates like a legal disqualification. Without meaningful enforcement mechanisms, the right to vote becomes hollow.
This Comment argues that implementing a national standard based on the proactive policies of Massachusetts and Nevada will ensure accessible voting for pretrial detainees. To build that argument, this Comment first explores the low level …
Conservatorship: An Enabler Of Involuntary Servitude, Jesse Long
Conservatorship: An Enabler Of Involuntary Servitude, Jesse Long
Arkansas Law Review
What happens when the conflict of interest relates to the conservatee’s substantial talents and their potential earnings? In this circumstance, a conservator has a perverse incentive to profit off of and coerce their conservatee into labor which serves to benefit the conservator—a kind of involuntary servitude that would seem to implicate the plain text of the Thirteenth Amendment of the United States Constitution.
This Note proceeds in three parts. Part I describes the history of conservatorships, why they were created, and the problematic issues that have arisen from the conservatorship system. Part II analyzes how the lack of meaningful judicial …
Exploring The Experiences Of Higher Education Students With Invisible Disabilities, Haley Malinverno
Exploring The Experiences Of Higher Education Students With Invisible Disabilities, Haley Malinverno
Culture, Society, and Praxis
This research analyzes textual data derived from Reddit communities to examine the lived experiences of higher education students and alumni with invisible disabilities (swID). The application of concepts and models of critical disability theory (CDT) are adopted to contextualize student experiences. This study answers two research questions, the first being: R1 - How do reported barriers impact swID in higher education? I find that barriers faced by swID relate to inequities of systemic ableism, with difficulties being a direct side-effect of the inflexible nature of academia. These barriers impact swID in the following ways: The demands of higher education causes …
#Diydiabetes: Type One Diabetes, Stigma, And Control In Digital Networks Of Diy Looping, Sophia M. Shelley
#Diydiabetes: Type One Diabetes, Stigma, And Control In Digital Networks Of Diy Looping, Sophia M. Shelley
Culture, Society, and Praxis
The general public’s awareness of type one diabetes is often lacking and filled with misinformation that can lead to stigma around the disability. Often type one diabetics have to fend for themselves through the means of “DIY diabetes.” The delay in technological innovations and the slow approval rate of Health Canada, compared to the US Food and Drug Administration, makes improving the lives of those with diabetes much more challenging. The self-management of the disability enables diabetics to take agency of their treatment plan and is the primary reason for DIY diabetes. The main reason for this research is to …
Global Prevalence Of Hyperhomocysteinemia Among Adults With Hypertension: A Narrative Review, Wangkheimayum Ashalata Devi Phd Scholar, Dr. Melita Sheilini Associate Professor, Dr. Rinchen Doma Bhutia Assistant Professor, Corresponding Author: Dr.Melita Sheilini, Associate Professor,Department Of Medical-Surgical Nursing, Manipal College Of Nursing, Manipal Academy Of Higher Education, Manipal, Udupi District, Karnataka, India.Contact Number- 8095976561. Email Id: [email protected]
Global Prevalence Of Hyperhomocysteinemia Among Adults With Hypertension: A Narrative Review, Wangkheimayum Ashalata Devi Phd Scholar, Dr. Melita Sheilini Associate Professor, Dr. Rinchen Doma Bhutia Assistant Professor, Corresponding Author: Dr.Melita Sheilini, Associate Professor,Department Of Medical-Surgical Nursing, Manipal College Of Nursing, Manipal Academy Of Higher Education, Manipal, Udupi District, Karnataka, India.Contact Number- 8095976561. Email Id: [email protected]
Manipal Journal of Nursing and Health Sciences
Background: Elevated blood homocysteine (Hcy) levels are a hallmark of hyperhomocysteinemia (HHcy), a metabolic disorder that is known to be a risk factor for cardiovascular illnesses. It greatly raises the risk of vascular problems when combined with hypertension (HTN). However, there are few statistics on the prevalence of HHcy in individuals with HTN. Objective: The present review aims to estimate the global prevalence of HHcy among adults with HTN and to highlight regional disparities, associated risk factors, and implications for clinical practice. Method: The comprehensive literature search was conducted using the PubMed and Google Scholar search engines. Studies published in …
Effectiveness Of Mobile Health Interventions On Cardiovascular Health Among Young Adults – A Systematic Review Protocol, Charlet Jasmine Vaz Mrs, Melita Sheilini Dr, Linu Sara George Dr, Edlin Glane Mathias Dr, Vani Lakshmi R Dr
Effectiveness Of Mobile Health Interventions On Cardiovascular Health Among Young Adults – A Systematic Review Protocol, Charlet Jasmine Vaz Mrs, Melita Sheilini Dr, Linu Sara George Dr, Edlin Glane Mathias Dr, Vani Lakshmi R Dr
Manipal Journal of Nursing and Health Sciences
Abstract
Introduction: Globally, cardiovascular diseases (CVDs) continue to be the primary cause of death and healthcare costs despite significant advancements in treatment effectiveness. The majority of deaths related to CVDs are highly common in countries with middle and low incomes. Objective: To determine the effectiveness of mobile health interventions on cardiovascular health among young adults. Method: A Search will be conducted using PICO format. Primary studies will be searched through electronic databases: Scopus, PubMed (MEDLINE), Web of Science, ProQuest, Embase and CINAHL(Ebsco). The review will only include studies conducted between January 2010 to July 2024 in English. Two authors will …
Effect Of Planned Teaching On The Necklace Method Of Natural Family Planning Among Female Students In Moodbidri, Manisha S. Poojary, Prof. Jenviv Kavitha D,Silva
Effect Of Planned Teaching On The Necklace Method Of Natural Family Planning Among Female Students In Moodbidri, Manisha S. Poojary, Prof. Jenviv Kavitha D,Silva
Manipal Journal of Nursing and Health Sciences
Introduction: The necklace method is a contemporary natural family planning approach that empowers women by enhancing accessibility, addressing knowledge deficiencies, and assisting couples in effectively planning and spacing their pregnancies. Objectives: This study aimed to evaluate the effectiveness of a structured teaching program on the knowledge of the necklace method as a natural family planning method among female students. Methods: A quantitative research design with a quasi-experimental approach, utilising a one-group pre- and post-test format, was employed. The study involved 60 female students from selected degree colleges in Moodbidri. Participants were chosen using a probability stratified random sampling technique. Data …
Impact Of The Covid-19 Outbreak On The Emotional Responses And Self-Protective Behaviors Of Nursing Students., Banisha Lyngdoh Nonglait, Jyothsna Jennifer Hans, S P Sagar, Gayatri Poojari, Sanju Pant, Maria Pais Dr
Impact Of The Covid-19 Outbreak On The Emotional Responses And Self-Protective Behaviors Of Nursing Students., Banisha Lyngdoh Nonglait, Jyothsna Jennifer Hans, S P Sagar, Gayatri Poojari, Sanju Pant, Maria Pais Dr
Manipal Journal of Nursing and Health Sciences
Background: The COVID-19 pandemic has disrupted nearly every aspect of our society. The higher education sector is no exception. Students face an increasingly unstable environment, impacting their physical and emotional health.
Objectives: The study aims to determine students' emotional responses to the impacts of the COVID-19 outbreak. It also assesses their behavior in protecting themselves from cross-contamination during this period.
Methods: A descriptive survey design was used in this study, which included 61 undergraduate students. To collect data, researchers employed socio-demographic questionnaires alongside a structured attitude survey designed to assess emotional responses and self-protective behaviors related to COVID-19. The reliability …
Evaluating The Impact Of Targeted Training On The Attitude And Knowledge Of Evangelical Pastors On Hiv In Tamil Nadu: A Pre-Test Post-Test Study, Ruth Duraiswamy Mrs
Evaluating The Impact Of Targeted Training On The Attitude And Knowledge Of Evangelical Pastors On Hiv In Tamil Nadu: A Pre-Test Post-Test Study, Ruth Duraiswamy Mrs
Manipal Journal of Nursing and Health Sciences
Abstract
Introduction: HIV/AIDS continues to be a significant global health challenge, with persistent stigma and misinformation hindering effective management, particularly within faith-based communities. Hence a study aimed to evaluate the impact of targeted training on the attitudes and knowledge of evangelical pastors in Tamil Nadu, India, regarding HIV was organized so that the pastors who are faith leaders in the Christian community can work towards removing stigma and ill treatment of HIV patients in the society. Objective: the objectives of the study were to assess the baseline knowledge and attitudes of evangelical pastors in Tamil Nadu regarding HIV, providing …
Website Transparency Of Ophthalmology Residency Programs: A Cross-Sectional Study, Aaishwariya Gulani, Sruti Sai Rachapudi, Cherie Fathy, Fasika Woreta
Website Transparency Of Ophthalmology Residency Programs: A Cross-Sectional Study, Aaishwariya Gulani, Sruti Sai Rachapudi, Cherie Fathy, Fasika Woreta
Journal of Academic Ophthalmology
Background: There is an increasing call for transparency in the ophthalmology residency application process. With programs shifting to virtual interviews, the availability of information regarding each program is limited to website searches, which as is, are not reflective of the programs and what they offer to potential residents.
Purpose: To assess the transparency of the residency application process through assessment of program for the period 1 November 2022 to 31 December 2022.
Methods: Four main categories of variables were studied: selection criteria, interview process, program priorities, and program requirements. Every program’s website was reviewed and the four …
Quantifying Research Productivity Among Matched Ophthalmology Applicants: Insights From The 2024 Residency Cycle, Sebastian Borges, Kara M. Cavuoto, Chris R. Alabiad
Quantifying Research Productivity Among Matched Ophthalmology Applicants: Insights From The 2024 Residency Cycle, Sebastian Borges, Kara M. Cavuoto, Chris R. Alabiad
Journal of Academic Ophthalmology
Background: Matching into ophthalmology has become increasingly competitive, with the overall match rate declining from 78% in 2020 to 66% in 2024. With the transition of USMLE Step 1 to pass/fail, residency selection committees may place greater emphasis on other objective metrics, including research productivity, which appears to be growing in significance.
Purpose: To quantify the research output of matched ophthalmology applicants in 2024 and to correlate descriptive statistics for research productivity with matching into top programs.
Methods: A publicly available medical student–maintained spreadsheet was used to identify matched applicants in 2024. Data was cross-verified using SF …
Optimizing Solvent Composition For Enhanced Extraction Of Phenolic Content And Antioxidant Activity From Coleus Scutellarioides Through I-Optimal Mixture Design, Sinta Mutiara Dwi Lestari, Utami Dyah Syafitri, Waras Nurcholis
Optimizing Solvent Composition For Enhanced Extraction Of Phenolic Content And Antioxidant Activity From Coleus Scutellarioides Through I-Optimal Mixture Design, Sinta Mutiara Dwi Lestari, Utami Dyah Syafitri, Waras Nurcholis
The Thai Journal of Pharmaceutical Sciences
Background: Reactive oxygen species are unstable molecules that contribute to oxidative stress and are associated with numerous degenerative diseases. The leaves of Coleus scutellarioides are rich in phenolic and flavonoid compounds, which possess strong antioxidant properties.
Objectives: This study aimed to optimize the composition of water, ethanol, and methanol as solvents using the I-optimal mixture design to enhance the extraction of total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and ferric reducing antioxidant power (FRAP).
Methods: Each extraction was performed by macerating 1 g of powdered C. scutellarioides leaves in 20 mL of the designated …
Hot-Melt Extrusion-Based Solid Dispersion Of Aripiprazole: Preparation, Characterization, And In Vitro Evaluation, Nensi Raytthatha, Jigar Ramanlal Vyas
Hot-Melt Extrusion-Based Solid Dispersion Of Aripiprazole: Preparation, Characterization, And In Vitro Evaluation, Nensi Raytthatha, Jigar Ramanlal Vyas
The Thai Journal of Pharmaceutical Sciences
Background: Aripiprazole (ARI), a biopharmaceutics classification system (BCS) class IV drug, exhibits poor water solubility and low permeability, resulting in limited bioavailability. Addressing these challenges requires innovative approaches to enhance solubility. This study focuses on the development and evaluation of solid dispersions (SDs) of ARI using “hot-melt extrusion,” (HME) a scalable and solvent-free method known for its ability to create stable amorphous structures. Soluplus® (SP) and Kollidon® 30 were employed as hydrophilic polymeric carriers to improve the solubility and stability of the amorphous drug form. Results: SDs were prepared by taking drugs and carriers (SP and Kollidon …
Developing Digital Feedback Literacies In Language Teacher Education: Peer And Partnership Approaches In The Postdigital Age, Jennifer Schluer
Developing Digital Feedback Literacies In Language Teacher Education: Peer And Partnership Approaches In The Postdigital Age, Jennifer Schluer
Journal of Media Literacy Education
Critical media literacy needs to be seen as a central component of language teacher education, especially in the postdigital age. One underexplored dimension, however, is digital assessment literacy and in particular digital feedback literacy (Schluer, 2022a). Even though recent years witnessed a proliferation of digital technologies for feedback exchanges, pedagogical guidance for the use of digital feedback remains almost non-existent (but see Schluer, 2022a; 2023; 2024a). Theoretically, this paper connects the concept of Digital Feedback Literacies (DFL) to the frameworks of Critical Media Literacies (CML) and Postdigital Literacies (PDL). Empirically, it presents insights from research on digital peer feedback as …