Digital Commons Network^™

Refining Population-Level Measures Of Early Childhood Vaccination Coverage Using National Immunization Survey-Child Data, Alexandria Nicole Albers

Graduate Student Theses, Dissertations, & Professional Papers

Background: From 2011-2021, the U.S. Advisory Committee on Immunization Practices (ACIP) recommended 10 vaccine series by age 24 months, with guidelines for minimum vaccination age, maximum age for rotavirus vaccination, minimum dose intervals, and a catch-up schedule for delayed series initiation. National vaccination surveillance evaluates series completion based on whether children received the recommended number of doses, including a combined 7-vaccine metric (completed seven series collectively). However, this approach overlooks: 1) vaccinations given too early, too late, or too close together, 2) catch-up schedule vaccinations, and 3) completion of all 10 recommended vaccines.

Purpose: To refine national childhood vaccination coverage …

"I'Ve Never Felt A Pain Like This" A Dialogic Analysis Of Parent-Child Estrangement Narratives On Reddit, Grant W. Lane

Graduate Student Theses, Dissertations, & Professional Papers

How do adult children estranged from their parent(s) create meaning and make sense of their estrangement in Reddit posts on the subreddit r/EstrangedAdultChild? This study analyzed Reddit posts written by estranged adult children for a presumed audience of other estranged adult children. Using relational dialectics theory (RDT) as a lens for analysis, this research examined the competing discourses that influence the meaning-making and sense-making processes of estranged adult children in their posts when the intended audience is fellow estranged adult children. Seventy-four posts from r/EstrangedAdultChild, authored by adult children who self-identified as estranged from at least one parent, were collected …

Intercellular Mitochondrial Transfer Contributes To Microenvironmental Redirection Of Cancer Cell Fate, Julie Sofie Bjerring, Yara Khodour, Emilee Anne Peterson, Patrick Christian Sachs, Robert David Bruno

School of Medical Diagnostics & Translational Sciences Publications

The mammary microenvironment has been shown to suppress tumor progression by redirecting cancer cells to adopt a normal mammary epithelial progenitor fate in vivo. However, the mechanism(s) by which this alteration occurs has yet to be defined. Here, we test the hypothesis that mitochondrial transfer from normal mammary epithelial cells to breast cancer cells plays a role in this redirection process. We evaluate mitochondrial transfer in 2D and 3D organoids using our unique 3D bioprinting system to produce chimeric organoids containing normal and cancer cells. We demonstrate that breast cancer tumoroid growth is hindered following interaction with mammary epithelial cells …

Secondhand Tobacco Smoke Exposure And Sleep Disturbance In School-Aged Children In Appalachian Ohio, Ketrell Mcwhorter, Christine Kim, Timothy J. Hilbert, Danielle E. Mcbride, Anthony A. Mangino, Patrick J. Parsons, Kurunthachalam Kannan, Erin N. Haynes

Epidemiology and Environmental Health Faculty Publications

Introduction: Secondhand tobacco smoke (SHS) exposure remains a major public health concern for children and has been implicated in sleep disturbances through biological and behavioral mechanisms. Different methods of measuring SHS exposure have yielded inconsistent results. This study examined the relationship between SHS exposure and sleep among rural Appalachian 7–9-year-olds, utilizing three SHS measurements: natural log-transformed (ln) serum cotinine concentrations, dichotomized serum cotinine levels (≥0.05 vs. <0.05 ng/ml), and parent/caregiver report of ≥1 smoker in the home. We hypothesized SHS-exposed children would have a significantly higher prevalence of sleep disturbance—e.g., short sleep, frequent snoring, night awakenings—compared to unexposed, regardless of measurement method. Methods: We used data from the Marietta Community Actively Researching Exposure Study, a cohort of 404 children in Marietta and Cambridge, Ohio. Sleep disturbances were parent/caregiver-reported. Linear models were used for continuous outcomes to estimate beta coefficients; log-binomial models with generalized estimating equations (exchangeable correlation) were applied for dichotomized outcomes to estimate prevalence ratios (PR), each with 95% confidence intervals (CI). Results: Twenty-six percent of children had a parent/caregiver report of ≥1 sleep disturbance. There was a 35% increased prevalence of short sleep [PR = 1.35 (95%CI:1.02–1.80), p =.04] with each unit increase of ln serum cotinine levels, adjusting for age, sex, parent education, BMI percentile, and history of breathing difficulties in the past two years. Increasing ln serum cotinine levels were associated with a significant 5.5-min decrease in average sleep duration in age-adjusted models. Conclusions: Higher SHS exposure was associated with poorer sleep outcomes, with serum cotinine emerging as the only measure linked to short sleep, underscoring the importance of smoke-free environments, particularly in rural communities, and objective exposure assessment.

Posterior Circulation Stroke- A Case Report, Janet Alva, Shwetha Prabhu, Raghavendra Rao S

Manipal Journal of Nursing and Health Sciences

Background: Stroke is most commonly seen in individuals over 65 years of age. When it occurs in adults between 18 and 65 years, it is classified as a young stroke. Unusual presentations such as dizziness, visual disturbances, or sensory changes often contribute to delayed recognition. Early identification is crucial for preventing complications and enhancing neurological outcomes. Case presentation: A 34-year-old female presented to the emergency department with a sudden onset of dizziness, right-sided tingling and weakness, and blurred vision. The neurological examination revealed subtle signs of posterior circulation impairment. MRI brain stroke protocol demonstrated an acute posterior circulation infarct involving …

Modeling Healthcare Managerial And It Sophistication, Gary Hackbarth, Teuta Cata

Journal of International Technology and Information Management

Sophisticated healthcare managers understand that managing information and selecting technology are two related but separate skill sets. Information Technology Governance (ITG) allows healthcare organizations to deal with complex issues, compete effectively, and support patient needs by integrating managerial and IT sophistication to improve business performance. An organizational model that merges IT and managerial sophistication by improving ITG to forecast business outcomes must grasp the intricacies of technology to acquire, manage, and utilize information technology in alignment with business strategies. The proposed model differentiates between internal and external IT management strategic thinking, emphasizing the critical need to govern IT effectively by …

Missouri, Elizabeth Ford

Thin Blue Advantage: Police Exceptionalism and the Two-Tier System of Public Sector Collective Bargaining

Missouri law allows for both police and non-police collective bargaining, but before 2018 there were no agency mechanisms to adjudicate a failure to bargain.

In 2018, however, the state passed a statute dramatically constraining public sector unions, but the law exempted police. The Missouri Supreme Court found that exclusion to be an equal protection violation.

Connecticut, Elizabeth Ford

Thin Blue Advantage: Police Exceptionalism and the Two-Tier System of Public Sector Collective Bargaining

In general, the Connecticut commission is hostile to expansive definitions of mandatory subjects of bargaining, sometimes issuing decisions that are results-driven and an expression of a preference for the substance of the employer’s decision. There are a couple of distinctions between police and other units:

• The Commission is more likely to weigh safety on the side of bargaining for police than others.
• The Commission treats the requirement to bargain surveillance-based decision more expansively for non-police units than police-units.

The Commission is more likely to find subcontracting of police work to an outside agency to be a mandatory subject of bargaining.

Illinois, Elizabeth Ford

Thin Blue Advantage: Police Exceptionalism and the Two-Tier System of Public Sector Collective Bargaining

As compared with other states, the Illinois Labor Relations Board (“ILRB” or “Board) is unusually protective of the right to bargain. The Board is more protective still of the ability of police unions to bargain over employer decisions. In the last several years in cases involving the Chicago Police Department, the Board has moderated somewhat by, in key cases, refusing to issue a decision but rather holding the matter “in abeyance.” A few highlights follow:

• Only Police Have the Right to Interest Arbitration. The Illinois Labor Relations Act requires police bargaining units to resolve contractual impasses through interest arbitration. …

The Romanticization Of Human-Vampire Relationships: How 'Twilight' And 'The Vampire Diaries' May Prime Young Women To Accept Dating Violence, Natalie M. Bowen

UROP Posters

The first literary vampire can be traced back to 18th century Germany, with Johann Wolfgang von Goethe’s poem “Die Braut von Korinth,” but the stereotypical features of a vampire are traditionally accredited to Bram Stoker’s Dracula. Modern vampires, such as Edward Cullen and Stefan Salvatore of the Twilight and The Vampire Diaries series respectively, have managed to win the hearts of teenage girls all across America with their sex appeal and charismatic nature. According to Bandura’s Social Cognitive Theory, individuals learn new behaviors by modeling and imitating the actions of those around them. This comprehensive literature review investigates the connection …

Analysis Of Differential Gene Expression In Androgen-Independent Clones Derived From The Mycap Pca Cell Line, Jessie L. Tignor, Melanie Sinanian, Richard Inho Joh, David Gewirtz, Jason Reed

UROP Posters

Androgen deprivation therapy (ADT) is a primary treatment strategy for prostate cancer (PCa), yet many tumors eventually develop androgen independence, leading to treatment resistance. To investigate the molecular changes underlying this transition, we analyzed differential gene expression in four androgen-independent (AI) clones derived from the Myc-CaP prostate cancer cell line using RNA sequencing. Gene expression profiles were compared to the parental Myc-CaP line, and differentially expressed genes (DEGs) were identified using DESeq2 and edgeR. The AI clones exhibited significant downregulation of senescence-associated genes, including Ezh2 and lamin B1, suggesting a loss of senescence-related chromatin repression. Additionally, upregulation of Wnt pathway …

Systematic Co-Culture Of Ipsc-Cm And Ipsc-An Promote Co-Maturation In Vitro, William Gregory Terrell Jr.

Graduate Dissertations and Theses

The cardiac microenvironment is a complex system of multicellular interactions that enables proper heart function. In native heart muscle, sympathetic neurons (SN) and parasympathetic neurons (PSN) modulate the beat rate of cardiomyocytes (CM) to maintain homeostasis. Pluripotent stem cells can differentiate into CM, but differentiated CMs are fetal-like, with a high beat rate, and lack organized sarcomeric structure. Recent reports of co-cultured pluripotent CM/SN pairs have reported electrophysiological changes in the SN (increased upstroke velocity). However, interpretation of these results are obscured by the differences in co-culture parameters between studies (stage of development, co-culture duration, etc.). The goal of this …

End-Less, Marzo Kaisin

Grado en Gestión y Comunicación de la Moda

END-LESS es una marca de moda de segunda mano que busca redefinir el valor percibido de las prendas a través de la narrativa, la autenticidad y la sostenibilidad.

Al crear un nuevo sistema de compra y venta, END-LESS ofrece una nueva experiencia para el usuario, creando un proceso de imaginación detrás de la indumentaria y de su historia. La esencia de la marca se basa en un modelo de negocio que expone narrativas, características y elementos que rodean a cada prenda. Mediante componentes sensoriales, tanto visuales como auditivos, el usuario logra sumergirse en un proceso de compra único, en el …

The Uptake Puzzle In Expungement Of Criminal Records, Jessica K. Steinberg, Elenore Wade

GW Law Faculty Publications & Other Works

Expungement has an uptake problem. A recent explosion of state-level rights allows people with felony convictions to expunge their criminal record, but only 1 to 6 percent of eligible people avail themselves of the remedy. Expungement is a powerful policy tool that promotes social and economic reintegration. It also serves a dignitary purpose, allowing people with criminal records to unshackle themselves from past mistakes. One might assume people would rush to court to clear their records. That the opposite is occurring—and new laws are idling on the books—suggests that rights-creation in this space has not been efficacious. This demands a …

Prima Facie Regulatory Capture: Lessons From Epa’S Regulation Of Glyphosate And Pfas ‘Forever Chemicals’, Jason Maclean

Minnesota Journal of Law, Science & Technology

No abstract provided.

One Step Forward, Two Steps Back: The United States’ New Direction On Digital Trade

Minnesota Journal of Law, Science & Technology

No abstract provided.

Fine-Tuned Large Language Models (Llms): Improved Prompt Injection Attacks Detection, Md Abdur Rahman, Hossain Shahriar, Guillermo Francia, Fan Wu, Alfredo Cuzzocrea, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

Large language models (LLMs) are becoming a popular tool as they have significantly advanced in their capability to tackle a wide range of language-based tasks. However, LLMs applications are highly vulnerable to prompt injection attacks, which poses a critical problem. These attacks target LLMs applications through using carefully designed input prompts to divert the model from adhering to original instruction, thereby it could execute unintended actions. These manipulations pose serious security threats which potentially results in data leaks, biased outputs, or harmful responses. This project explores the security vulnerabilities in relation to prompt injection attacks. To detect whether a prompt …

Vulnerability To Stability: Scalable Large Language Model In Queue-Based Web Service, Md Abdul Barek, Bajlur Rashid, Mostafizur Rahman, A.B.M. Kamrul Islamc Riad, Guillermo Francia, Hossain Shahriar, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

Large Language Models (LLMs) have demonstrated exceptional capabilities in the field of Artificial Intelligence (AI) and are now widely used in various applications globally. However, one of their major challenges is handling high-concurrency workloads, especially under extreme conditions. When too many requests are sent simultaneously, LLMs often become unresponsive which leads to performance degradation and reduced reliability in real-world applications. To address this issue, this paper proposes a queue-based system that separates request handling from direct execution. By implementing a distributed queue, requests are processed in a structured and controlled manner, preventing system overload and ensuring stable performance. This approach …

Contextual Embedding-Based Clustering To Identify Topics For Healthcare Service Improvement, K M Sajjadul Islam, Ravi Teja Karri, Srujan Vegesna, Jiawei Wu, Praveen Madiraju

Computer Science Faculty Research and Publications

Understanding patient feedback is crucial for improving healthcare services, yet analyzing unlabeled short-text feedback presents challenges due to limited data and domainspecific nuances. Traditional supervised approaches require extensive labeled datasets, making unsupervised methods more practical for extracting insights. This study applies unsupervised techniques to analyze 439 survey responses from a healthcare system in Wisconsin, USA. A keyword-based filter was used to isolate complaint-related feedback using a domain-specific lexicon. To identify dominant themes, we evaluated traditional topic models such as Latent Dirichlet Allocation (LDA) and Gibbs Sampling Dirichlet Multinomial Mixture (GSDMM) - alongside BERTopic, a neural embedding-based clustering method. To improve …

Measuring Toluene Diisocyanate Concentrations In Accordance With Acgih® Inhalable Fraction And Vapor (Ifv) Notation, Charles Larocque, Pierre-Luc Cloutier, Sébastien Gagné, Loïc Wingert, Sylvain Canesi, Jacques Lesage, Simon Aubin

Études primaires

Toluene diisocyanate (TDI) is an irritant (skin, eye and respiratory) and a sensitizer. This compound is used to manufacture polyurethane materials such as flexible foams. The use of isocyanates may lead to exposure by inhalation and/or skin contact and isocyanates are recognized as a cause of occupational asthma. The American Conference of Governmental Industrial Hygienists (ACGIH^®) recommends a threshold limit value (TLV) for TDI of 1 part per billion (ppb) (7 µg m-^³) with inhalable fraction and vapor (IFV) notation. This notation means that the inhalable fraction of particles and the vapor phase of TDI may …

Évolution Des Troubles Mentaux Liés Au Travail Au Québec Entre 2012 Et 2021, Jaunathan Bilodeau, Martin Lebeau, Marc-Antoine Busque, Alain Marchand

Études primaires

Introduction : Plusieurs pays ont connu une augmentation du nombre de troubles mentaux acceptés au cours des dernières années, mais les variations possibles de cette évolution dans la main-d’œuvre demeurent à explorer.

But de l’étude : Cette étude examine la distribution dans le temps des troubles mentaux acceptés selon la profession, le secteur industriel, le sexe et l’âge au Québec.

Résultats : Les taux d’incidence des troubles mentaux et leur évolution varient selon la profession et le secteur industriel. Alors que le taux est généralement plus élevé dans les professions mixtes et le secteur tertiaire, l’augmentation de ces taux s’observe …

Revitaización De Late Checkout, Daniel Martín Rodríguez

Grado en Gestión y Comunicación de la Moda

Este Trabajo de Fin de Grado aborda la revitalización de Late Checkout, una marca española de moda urbana que ha logrado posicionarse en el panorama contemporáneo gracias a su propuesta estética inspirada en el universo hotelero y a un storytelling que aúna lujo accesible, cultura digital y exclusividad. Fundada en 2019 por el estilista Alex Turrión, la firma se enfrenta actualmente al reto de consolidar su identidad independiente, alejándose estratégicamente de su asociación inicial con figuras mediáticas como C. Tangana, sin renunciar a los valores que cimentaron su éxito.

El proyecto se estructura en tres fases: análisis de contexto y …

A.R.A.Y. (2025), Lucía Martín Romero

Grado en Diseño de Moda

El proyecto pretende ahondar el concepto de identidad individual y como a través de las experiencias personales y el papel de los recuerdos esta se va moldeando a lo largo del tiempo, en un proceso que teóricamente no encuentra un punto final. A su vez, se trata de manera subyacente el término autoconocimiento, como parte del proceso de construcción identitaria, y como permite comprender nuestras emociones y la forma en la que actuamos. Se busca identificar y tratar aquellos factores que influyen y definen dicha identidad, haciendo especial énfasis en los recuerdos personales, utilizando como base teórica la obra “EL …

Aniela (2025), Blanca Vadillo Sánchez

Grado en Diseño de Moda

Hay cosas que no se dicen, pero permanecen. Una prenda, a veces, es eso: una forma de quedarse, de insistir sin imponerse, de sostener algo que aún no tiene nombre. Este proyecto no propone una respuesta, sino una serie de aproximaciones a través del diseño, el cuerpo y el tiempo. Se parte de una pregunta simple pero insistente: ¿qué significa permanecer cuando todo parece pensado para desaparecer? En un contexto marcado por la velocidad del consumo, por el ritmo acelerado de una industria que produce sin pausa y olvida con rapidez, Aniela propone otra temporalidad. Una más atenta, más situada. …

Vestuario Escénico. La Caída De La Casa Usher (2025), Miren Rosado

Grado en Diseño de Moda

No abstract provided.

The Stage. Fashion Branding Agency (2025), María Rodríguez Jaro

Grado en Diseño de Moda

Este Trabajo de fin de grado se centra en la creación de una agencia de comunicación de moda especializada en branding para marcas emergentes. En un sector saturado y altamente competitivo, estas marcas suelen enfrentar desafíos significativos para destacar debido a la falta de una identidad sólida y estrategias de comunicación efectivas. Esta situación limita su capacidad para conectarse emocionalmente con su público objetivo y, por fin, alcanzar un crecimiento sostenible.

“La mente es selectiva, y si la marca no pasa por el corazón y emociona, se olvida” (Urrea, 2016), esto ocurre debido a la falta de una estrategia de …

They Never Saw It Coming: Frames Of Intimate Partner Homicide On Crime Science Investigation (Csi), Tracy Sohoni, Julie Snell, Elizabeth Harden

Sociology & Criminal Justice Faculty Publications

Purpose

While portrayals of intimate partner homicide (IPH) in news media have been extensively studied, research on depictions of IPH in television crime dramas has been largely absent despite the fact that crime-dramas have a wide audience and have been shown to have a significant influence on viewers' social attitudes.

Methods

We conduct a thematic content analysis of portrayals of intimate partner homicide across four seasons of the crime-drama Crime Scene Investigation (CSI) and compare these depictions to research on common warning signs and patterns of IPH.

Results

Similar to research on news media, CSI depicts IPH in ways that …

Halotolerant Biodegradation And Detoxification Of Synthetic Dyes By Marine-Derived Penicillium Oxalicum M6a: Metabolite Profiling And Ecotoxicity Assessment, Ugochukwu Okechukwu Ozojiofor, Mohammed Sani Abdulsalami, Nkechi Eucharia Egbe, Ahmed Ali Haroun, Yakubu Magaji

Applied Environmental Research

The complex aromatic structures of synthetic dyes in contaminated water bodies make them difficult to degrade, posing a serious environmental challenge and representing a significant emerging pollutant that warrants urgent intervention. This study evaluated the biodegradation and detoxification potential of a halotolerant, marine-derived fungal strain, Penicillium oxalicum M6A, isolated from the Nigerian coastline, against Indigo carmine (IC) and Remazol Brilliant Blue R (RBBR). The effects of pH, temperature, salinity, and dye concentration on degradation efficiency, alongside enzymatic activity, were assessed. FTIR and GC‒MS analyses were employed to identify degradation products and predict metabolic pathways, whereas toxicity was evaluated in three …

Assessment Of Metal Contamination And Potential Health Risk Of Roadside Vegetables Along The Sayre Highway, Province Of Bukidnon, Philippines, John R.N. Labajo, Junesa U. Cristobal, Myrna G. Pabiona

Applied Environmental Research

This study assessed heavy metal contamination in roadside vegetables (Ipomoea batatas and Moringa oleifera) across five urbanized localities in Bukidnon, Philippines, and evaluated potential human health risks. Metal concentrations (Cd, Cr, Cu, Co, Fe, Mn, and Zn) were analyzed via atomic absorption spectro-photometry and compared against FAO/WHO maximum permissible limits. The results revealed severe contamination, with Mn (575.27–862.17 mg kg-1) and Fe (256.46–706.68 mg kg-1) dominating natural soil mineralogy (Adtuyon series) and anthropogenic inputs. Toxic Cr (16.20–21.93 mg kg-1) exceeded permissible limits by nine and a half times in Quezon. Health risk assessments revealed negligible noncarcinogenic risks (THQ …

Spatial Distribution And Potential Ecological Risk Of Microplastics In Surface Sediments Of The Inner Gulf Of Thailand, Sarayut Suanluang, Pathompong Vibhatabandhu, Sarawut Srithongouthai

Applied Environmental Research

The global surge in plastic usage during the COVID–19 pandemic raised concerns about increased microplastic (MP) contamination in aquatic environments. This study assessed the abundance, characteristics, and ecological risk of MPs in surface sediments of the inner Gulf of Thailand during the post–COVID–19 period (April 2021). The sediment samples were analyzed via density separation, stereomicroscopic examination, and polymer identification via micro–FTIR. The mean MP abundance was 196.07 ± 85.60 pieces kg-1, with concentrations ranging from 73.08 to 351.19 pieces kg-1. PTFE and PP were the dominant polymer types, comprising 50% and 32% of all the MPs, respectively. Fibers (34%) and …