Digital Commons Network^™

Probabilistic Modeling Of Antibody Kinetics Post Infection And Vaccination, Rayanne Luke, Prajakta Bedekar, Anthony J. Kearsley

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Integration Of High-Resolution Behavioral Data Into Mathematical Models For Public Health Applications, Giulia Pullano

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Representing Ewe-Lamb Contact Dynamics In An Agent-Based Model Of Enzootic Abortion Of Ewes, Kelly R. Buch, Cara J. Sulyok

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Commercial Laying Hen Farms' General Characteristics, Environmental Management, And Biosecurity Practices In The Sub-Arid Area Of Algeria, Yacine Kasmi, Nouzha Heleili, Zohra Ahmed Gaid, Brahim Hamad, Leyla Hadef, Manel Merradi

The Thai Journal of Veterinary Medicine

The success of commercial laying hen farms depends on the possibility of managing environmental conditions properly and performing strict biosecurity measures, which would increase productivity, enhance the performance of the flock, and save money, especially in regions characterized by challenging climatic conditions, such as the sub-arid and arid areas. There is, however, very little literature exploring these issues in the Algerian context. The objective of the study was to assess environmental management and biosecurity practices, and the relationship between these and farm size in the Algerian sub-arid area (northeast Algeria). The face-to-face interviews were conducted between January 2024 and April …

Untargeted Metabolomics Reveals Organ-Specific And Extraction-Dependent Metabolite Profiles In Endemic Tajik Species Ferula Violacea Korovin, Sylhiya Mavlonazarova, Kenneth Acosta, Rinat Abzalimov, Saidbeg Satorov, Vyacheslav Dushenkov

Publications and Research

Ferula violacea Korovin, an endemic Tajikistani plant with purported medicinal properties, remains understudied. This study employs untargeted metabolomics to characterize the metabolite profiles of ethanol extracts and juices from F. violacea roots and seeds. In total, 540 distinct metabolites are putatively identified, 419 of which are previously unreported in the Ferula genus, representing a substantial expansion of its known chemical diversity. The most abundant metabolites are terpenoids, amino acid derivatives, and alkaloids. A particularly abundant group of daucane sesquiterpenoids, sharing a common (6-methyl-azulen-4-yl) cyclohexanecarboxylate substructure, is identified, including known metabolites such as ferutidin and ferutinin. Comparative analysis reveals organ-specific metabolic …

The Impacts Of Metapopulation Structure On Infectious Disease Dynamics, Éowyn M. Poplawski, David Brown

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling The Impact Of Treatment During An Ongoing Tuberculosis Outbreak, Bach Le, Jude Shive, Erin N. Bodine

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling, Analysis And Simulation With Optimal Control Applied To Malnutrition, Dia Bonsu

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modeling, Analysis And Simulation To Study The Multi-Stage Dynamics Of Student Debts, Paula Navarro Ortiz, Nathan Bezabeh

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

The Cost Of Our Constitutional Rights: An Examination Of Prison Medical Treatment For Hepatitis-C, M. Abigail Schueler

Kentucky Law Journal

No abstract provided.

Molecular Screening Of Avian Viruses And Parasites In Wedge-Tailed Shearwaters Ardenna Pacifica And Barau’S Petrels Pterodroma Baraui On Réunion Island, Camille Lebarbenchon, Celine Toty, Solenn Boucher, Audrey Jaeger, Matthieu Le Corre

Marine Ornithology

We investigated Wedge-tailed Shearwater Ardenna pacifica and Barau's Petrel Pterodroma baraui exposure to infectious agents circulating in the western Indian Ocean. Using polymerase chain reaction and serological analyses, we screened for influenza viruses, flaviviruses, coronaviruses, and blood parasites (Haemoproteus, Leucocytozoon, and Plasmodium). No active infections were detected and serological results suggested limited past exposure, with only two Wedge-tailed Shearwaters testing positive for antibodies to the influenza A virus. These findings indicate the limited role of these species as epidemiological reservoirs. However, environmental factors such as tick infestations and isolated breeding habitats highlight the need for continued epidemiological monitoring to support …

Updating The Status Of The Peruvian Pelican Pelecanus Thagus Following Avian Influenza And El Niño Events In Peru, Liliana Ayala, Gabriela Sandoval-Lazaro

Marine Ornithology

The Peruvian Pelican Pelecanus thagus is an endemic species of the Humboldt Current System. Between November 2022 and March 2024, the avian influenza epidemic and El Niño conditions significantly affected the pelican population. This study provides an update on the population size and breeding status of the species in Peru. Pelican abundance decreased by 31.5% to 37.6% within marine protected areas. The number of live pelicans ranged from 1,652 to 46,046 in 2023 and from 14,505 to 52,540 in 2024, based on counts conducted in natural protected areas by Peruvian government officials. Breeding primarily occurred on six islands between October …

Occupational Health Nurse, Maryann Jensen

One Map, Limitless Destinations 2.0

No abstract provided.

Statistical Challenges And Simulation Results For Pilot Clinical Trials, Weiliang Cen

USF Tampa Graduate Theses and Dissertations

Background: The effect size estimated from a pilot trial is often an inaccurate reflection of the true effect size observed in a large trial, leading to either underestimation or overestimation. Published data suggest that effect sizes from large trials are typically smaller than those reported in their corresponding pilot trials. To address this discrepancy, conservative or discount adjustment methods are widely recommended to modify pilot trial effect sizes when calculating sample sizes, thereby maintaining adequate statistical power. This study aims to assess effect sizes from both pilot and large trials and to evaluate the performance of existing adjustment methods.

Methods: …

Citrobacter Sedlakii As A Rare Cause Of Brain Abscess In A Late-Preterm Omani Infant: Case Report And Literature Review, Mohammed S. Al Reesi, Moza Al Mamari, Sara Magzoub, Yasser Abdulrazek

Sultan Qaboos University Medical Journal

Brain abscess in neonates is rare but remains a severe, life-threatening complication of meningitis with significant morbidity and mortality. While Citrobacter koseri and Citrobacter freundii are commonly implicated in brain-abscess formation, Citrobacter sedlakii is an uncommon causative pathogen. To date, only two cases of neonatal brain abscess caused by C. sedlakii have been reported in the literature. Early diagnosis, timely surgical intervention and prompt antibiotic therapy are critical to achieving a favourable outcome. A third case of a C. sedlakii brain abscess in a preterm infant, presenting in 2024 to a tertiary-care hospital in Oman, is reported together with a …

Influenza Vaccine Effectiveness Against Medically Attended Outpatients Illness, United States, 2023-2024 Season, Jessie R Chung, Stacey L House, Tara Curley, Et Al.

2020-Current year OA Pubs

BACKGROUND: The 2023-2024 US influenza season was characterized by a predominance of A(H1N1)pdm09 virus circulation with cocirculation of A(H3N2) and B/Victoria viruses. We estimated vaccine effectiveness (VE) in the United States against mild-to-moderate medically attended influenza illness in the 2023-2024 season.

METHODS: We enrolled outpatients aged ≥8 months with acute respiratory illness in 7 states. Respiratory specimens were tested for influenza type/subtype by reverse-transcriptase polymerase chain reaction. Influenza VE was estimated with a test-negative design comparing odds of testing positive for influenza among vaccinated versus unvaccinated participants. We estimated VE by virus subtype/lineage and A(H1N1)pdm09 genetic subclades.

RESULTS: Among 6629 …

Critical Food Safety Violations In Food Facilities By Regions Across Calgary Communities From 2022 Versus 2023, Kamorudeen Olayinka Bakare

Walden Dissertations and Doctoral Studies

Critical food safety violations in food facilities are severe infractions that may affect the quality and safety of foods as well as the health and wellbeing of consumers in Canada. In 2023, Alberta Health Services heightened scrutiny on these violations in Calgary. However, no investigation has been undertaken to document its potential effects on types and trend (from the previous year) of food safety violations in food facilities across Calgary regions. The purpose of this quantitative study was to examine the associations between Calgary regions of Canada, Year (2022 versus 2023), and the number of types of critical food safety …

Prolonged Dysregulation Of Gene Expression And Biomarkers Of Coagulation, Fibrinolysis, And Endothelium In Pediatric Central Nervous System Malaria, Arlene E Dent, Bruce A Rosa, Katherine R Dobbs, Sidney Ogolla, David Midem, Paula Embury, Yelenna Skomorovska-Prokvolit, Emily R Hannon, Emmily Koech, Alvin H Schmaier, Walter Otieno, Makedonka Mitreva, James W Kazura

2020-Current year OA Pubs

BACKGROUND: Children with central nervous system malaria (CNS-M) have gene expression profiles and plasma biomarkers of malaria pathogenesis that differ from children with uncomplicated malaria (UM, malaria infection with fever and no systemic organ dysfunction) or acute febrile non-malaria illness (AFN). However, there is scant knowledge of the temporal dynamics of gene expression and plasma biomarkers during recovery from CNS-M.

METHODS: We compared serial changes of peripheral blood mononuclear cell transcriptomes at 6 weeks after recovery and plasma biomarkers of malaria pathogenesis at 6 weeks and 6 months after recovery in cohorts of Kenyan children who presented with CNS-M ( …

A Multi-Faceted Study Of Antibiotic-Resistant, Opportunistic Pathogens In Wastewater And Environmental Water, Jeanette Calarco

USF Tampa Graduate Theses and Dissertations

More than 2.8 million infections due to antibiotic-resistant bacteria occur annually in the United States, and more than 35,000 people die as a result. Domestic wastewater (sewage), which contains antibiotic-resistant bacteria and antibiotic resistance genes, is collected at treatment plants for removal of contaminants, e.g. pathogenic microorganisms and nutrients. While wastewater treatment is designed to remove antibiotic-resistant bacteria and other microorganisms through treatment and disinfection, some bacteria may escape treatment. Treated wastewater effluent is generally discharged into surface waters; however, some fraction of the effluent may be used as recycled water. Compromised wastewater collection infrastructure and sewage spills can disseminate …

Antibiotic Stewardship And The Prevention Of Healthcare-Associated C.Diff, Nevaeh Tyson, Angel Pearson

Scholars Week

Healthcare-associated Clostridium difficile (C.difficile) infections remain a significant burden to many healthcare facilities across North America. This infection is often linked to long-term antibiotic use and ineffective infection control methods. This presentation addresses current evidence-based practice protocols on the prevention of C.difficile, emphasizing the need for increased monitoring of antibiotic therapy and improved infection control strategies.

Understanding The Impact Of Wealth Inequality On Appalachian Health, Noah Wren

3 Minute Thesis Competition

No abstract provided.

Pacific Rxtracts - November 2025, Pacific Rxtracts

Pacific RxTracts

This issue features updates on the FDA approval of Papzimeos, the first immunotherapy for recurrent respiratory papillomatosis; the early success of stem cell-derived islet therapy in type 1 diabetes; and the use of oral Palonsify in the management of acromegaly.

You will also find additional highlights across several specialties such as endocrinology, oncology, neuropsychology, and infectious disease. Each article provides valuable insights to help you stay informed on the latest developments in pharmacy, and we encourage you to give them a read.

Large-Scale Profiling Of Antibody Reactivity To Glycolipids In Patients With Guillain-Barré Syndrome, Robin C M Thomma, Susan K Halstead, Laura C De Koning, Eveline J A Wiegers, Dawn S Gourlay, Anne P Tio-Gillen, Wouter Van Rijs, Henning Andersen, Giovanni Antonini, Samuel Arends, Shahram Attarian, Fabio A Barroso, Kathleen J Bateman, Luana Benedetti, Peter Van Den Bergh, Jan Bürmann, Mark Busby, Carlos Casasnovas, Efthimios Dardiotis, Amy Davidson, Thomas E Feasby, Janev Fehmi, Giuliana Galassi, Tania Garcia-Sobrino, Volkan Granit, Gerardo Gutiérrez-Gutiérrez, Robert D M Hadden, Thomas Harbo, Hans-Peter Hartung, Imran Hasan, James K L Holt, Zhahirul Islam, Summer Karafiath, Hans D Katzberg, Noah Kolb, Susumu Kusunoki, Satoshi Kuwabara, Motoi Kuwahara, Helmar C Lehmann, Sonja E Leonhard, Lorena Martín-Aguilar, Soledad Monges, Eduardo Nobile-Orazio, Julio Pardo, Yann Pereon, Luis Querol, Ricardo C Reisin, Simon Rinaldi, Paolo Ripellino, Rhys C Roberts, Olivier Scheidegger, Nortina Shahrizaila, Kazim A Sheikh, Nicholas J Silvestri, Soren H Sindrup, Beth Stein, Cheng Y Tan, Hatice Tankisi, Leo H Visser, Waqar Waheed, Ruth Huizinga, Bart C Jacobs, Hugh J Willison

Faculty, Staff and Student Publications

Guillain-Barré syndrome is an acute polyradiculoneuropathy in which preceding infections often elicit the production of antibodies that target peripheral nerve antigens, principally gangliosides. Anti-ganglioside antibodies are thought to play a key role in the clinical diversity of the disease and can be helpful in clinical practice. Extensive research into clinical associations of individual anti-ganglioside antibody specificities has been performed. Recent research has highlighted glycolipid complexes, glycolipid combinations that may alter antibody binding, as targets. In this study, we investigated antibody reactivity patterns to glycolipids and glycolipid complexes using combinatorial array, in relation to clinical features in Guillain-Barré syndrome. In total, …

Full Issue, Volume 4, Press Humboldt

CSU Journal of Sustainability and Climate Change

Volume 4, 2025

Solvent Extracts Of Pulvigera Papillosa (Orthotrichaceae) Show No Antimicrobial Properties In Disk Diffusion Tests, Ryan A. Solorzano, Justin Paulin, Grayson Prater, Michael Lanier

Humboldt Journal of Microbiology

Abstract As antibiotic-resistant bacteria become more prevalent, the search for novel forms of antibiotics in the natural world has become an increasingly worthwhile endeavor. Many mosses have been found to contain antimicrobial properties, including those in the family Orthotrichaceae. Pulvigera papillosa, an Orthotrichaceous moss native to California, has thus far not been investigated to determine whether it contains antimicrobial properties. Extraction techniques using polar and nonpolar solvents have proven to be effective in extracting the secondary metabolites that allow mosses to defend themselves against a hostile microbial world. This study takes a preliminary look into the antimicrobial properties of P. …

Antimicrobial Resistance In Ukraine—What Healthcare Providers Need To Know When Treating Ukrainian Refugees, Olga Vasylyeva

Advances in Clinical Medical Research and Healthcare Delivery

The scoping review assesses the trends in clinical infectious diseases reporting antimicrobial resistance (AMR) in Ukraine following a year of full-scale Russo-Ukrainian war (2022) to offer recommendations for healthcare providers caring for patients traveling from Ukraine.

Background: Until 2019, antibiotics were available to Ukrainians over the counter, and there was no systematic program to monitor bacterial resistance. Only in 2023 did a document standardizing the rational use of antibacterial and antifungal drugs become available for Ukrainian healthcare providers. By 2020, high levels of carbapenem-resistant bacteria were reported in military hospitals, 29.5%–64.2%, with Acinetobacter baumannii particularly problematic. Nosocomial infections were significantly …

Accidental Daily Dosing: Severe Methotrexate Toxicity In A Patient With Rheumatoid Arthritis, Sidra Memon, Kavitha Vemuri, Syed Uzair Mahmood, Darshit Patel

Advances in Clinical Medical Research and Healthcare Delivery

This case highlights a crucial complication of oral methotrexate therapy: toxicity due to dosing errors. A patient’s daily dosing regimen, instead of the intended weekly schedule, led to a significantly excessive cumulative dose of methotrexate over a short period, resulting in severe hematologic and mucosal toxicity. This underscores the importance of clear patient education and vigilant prescription practices to prevent such errors.

Impact Of Frailty On Inpatient Outcomes Of Covid-19 Patients: Evidence From A Us National Inpatient Sample, Ali Jaan, Priyanshi Shah, Ashish Dhawan, Saria Qaiser, Azka Ali, Hla Myo Thwe, Oluwatosin Abimbolu, Clara Chimuanya Okpara, Michael Rajnik

Advances in Clinical Medical Research and Healthcare Delivery

Introduction: The global impact of Coronavirus Disease 2019 (COVID-19), caused by severe-acute-respiratory-syndrome coronavirus 2 (SARS-CoV-2), has been profound, claiming the lives of more than 3 million individuals within a year and a half. Among the affected population, heightened vulnerability is observed among older and frailer individuals, leading to more severe symptoms and adverse outcomes compared to their younger, non-frail counterparts. This study to analyze the impact of frailty on the outcomes of adult patients admitted with COVID-19.

Methods: Using the National Inpatient Sample (NIS) database 2020, we identified adult patients admitted with a principal diagnosis of COVID-19. The …

Increasing Pediatric Hpv Vaccination Rates, Brooke A. Nicholas

Dissertations

Increasing Pediatric HPV Vaccination Rates

Abstract

Problem: The human papillomavirus (HPV) is a sexually transmitted infection that affects more than 80% of the population within the United States (Eisenhauer et al., 2020). HPV can develop into cervical, anogenital, and oropharyngeal cancers (Eisenhauer et al., 2020). About 4,000 individuals die from cervical cancer alone each year (O’Leary, 2022). The HPV vaccine, though recommended by the ACIP and AAP, is below national vaccination rates in comparison to other vaccines (O’Leary, 2022).

Methods: This quality improvement project is a non-randomized controlled trial that observed HPV vaccine dose completion rates for patients aged 9-14 …

Electrochemical Breath Sensors In Medical Diagnostics: Emerging Trends And Future Directions, Natalie E. Strom, Courtney J. Weber, Olja Simoska

Faculty Publications

With the rising prevalence of metabolic diseases, infections, and mental health disorders, there is a growing demand for noninvasive diagnostic tools that enable early detection and continuous health monitoring. In this context, exhaled breath biomarkers provide insight into physiological and pathological processes. Electrochemical breath sensors (EBSs) have emerged as a promising platform for rapid, real-time, and cost-effective disease tracking via the detection of volatile breath biomarkers, such as NH₃, NO, and CO₂. Recent advancements in electrode materials, biological recognition elements, and sensor architectures—spanning nanomaterials, enzymes, aptamers, and molecularly imprinted polymers—have enhanced the analytical performance of EBSs. …