Digital Commons Network^™

Long-Term Abundance Estimates Of A Northeast Florida Estuarine Dolphin Community: Evaluating The Impacts Of The 2013–2015 Cetacean Morbillivirus Unusual Mortality Event, Allison L. Wilkins

UNF Graduate Theses and Dissertations

Tamanend's bottlenose dolphins (Tursiops erebennus) in the St. Johns River (SJR), Jacksonville, FL, are subjected to substantial anthropogenic stressors (e.g., vessel traffic, dredging, fisheries interactions) and were heavily impacted by the 2013-2015 Mid-Atlantic cetacean morbillivirus unusual mortality event (UME). High prevalence of skin lesions and frequent sightings of emaciated dolphins suggest declining health and viability of the SJR dolphin community. Sighting data from Jul. 2011 to Oct. 2019 provided the rare opportunity to investigate long-term changes in dolphin abundance surrounding the UME. This study produced the first dolphin abundance estimate within the Jacksonville Estuarine System stock since 1997, …

Sulfur Chemistry For Protein Synthesis And Modification: From Thiolactone To Bicyclic Sulfoxide Frameworks, Yuming Wen

Electronic Theses & Dissertations (2024 - present)

This dissertation explores two intersecting themes in modern chemical biology: (1) the design of novel ligands for transition-metal catalysis, and (2) the development of thiolactone-mediated strategies for protein synthesis and modification in aqueous media. Together, these studies advance chemical methods for precise molecular transformations under mild, biocompatible conditions.

In the first chapter, a geometrically constrained bicyclic [3.3.1] sulfoxide framework was developed as a new class of bissulfoxide ligands for palladium-catalyzed C–H functionalization. The ligand was synthesized concisely from thiophenol through a three-step sequence and shown to promote allylic C–H amination and alkylation reactions with high efficiency. The catalytic system tolerated …

Perspectives On Demyelinating Disease: An Overview Of Multiple Sclerosis, Nathaniel Howard Williams

Senior Honors Theses

Multiple sclerosis (MS) is a demyelinating disease of central nervous system (CNS), primarily concerning oligodendrocytes, the myelinating cells of the CNS and the neurons that are ensheathed in myelin. MS is the most common demyelinating disease, affecting as many as 300,000 yearly in the United States alone. Much debate centers on whether MS onset is primarily caused by autoimmune reactions or intrinsic dysfunction in oligodendrocytes, which prompts an immune-mediated response. Those who review the current literature on MS may become quickly overwhelmed by the volume and variety of available material. The purpose of this review is to present a …

Α Novel Ai-Based Modeling With Bias Classification Hybrid Risk Evaluation System For Confidence Enhanced Network Meta-Analysis Of Occupational Hazards And Burnout Risk Among Public Health Inspectors, Ioannis Adamopoulos

Mesopotamian Journal of Artificial Intelligence in Healthcare

Public Health Inspectors (PHIs) serve a critical role in enforcing health and safety regulations, particularly under the growing pressures of climate change. With rising exposure to occupational hazards such as heat waves, air pollution, and vector-borne diseases, PHIs now face escalating stress and burnout. Geographical variability, limited resources, and institutional gaps in training and support further shape their complex risk profile. Despite growing concern, systematic, confidence-based evaluations of these occupational risks—especially tailored to PHIs—remain rare. This study addresses that gap using a Confidence in Network Meta-Analysis (CINeMA)-enhanced framework to assess domain-specific occupational risk profiles of PHIs working in climate-stressed environments. …

Machine Learning Approaches For Predicting Breast Cancer Recurrence: A Comparative Analysis, Noor Razzaq Abbas, Hussein Alkattan, Isam Bahaa Aldallal

Mesopotamian Journal of Artificial Intelligence in Healthcare

This paper reports a comparative analysis of four supervised machine learning algorithms: RF, SVM (using radial and linear kernels), Logistic Regression, and Multi-Layer Perceptron, for breast cancer recurrence prediction on a carefully curated clinical dataset. The data set, first collected by Royston and Altman and subsequently released on Kaggle, has patient age, menopausal status, tumor size, histological grade, lymph node status, estrogen and progesterone receptor levels, hormone therapy for treatment, recurrence-free survival time, and a binary recurrence outcome. The data set was then divided after the elimination of identifiers and z-score normalization in an 80:20 ratio using stratified sampling. Models …

Effects Of Essential Oils Alone Or In Combination With Monensin In An In Vitro Model Of Ruminal Acidosis, Jorge L. Bonilla Urbina

Electronic Theses and Dissertations

The objective of this study was to evaluate the effect of essential oils and/or monensin on the concentration of volatile fatty acids (VFA), ammonia, and pH in a ruminal acidosis in vitro model. Red Angus steers (n = 4; BW = 435 ± 9 kg) with ruminal and duodenal cannulas were allocated in a 4 × 4 Latin square design. Treatments were 1) Fed no essential oils (RB) or monensin sodium (MON:CON); 2) Fed RB at a rate of 14 g daily with no Mon (RB+); 3) Fed no RB and fed Mon at 400 mg daily (MON+); 4) Fed …

Minds, Made Up Or Malleable? Covert Commands At The Eclipse Of Vaccine Communications, David H. Lee

Publications and Research

Abstract: Although millions have died from SARS-CoV-2 illness, COVID vaccines are credited with stemming the tide. Vaccinations and boosters significantly decrease the incidence of severe illness and death (even if they don’t usually prevent COVID-19 infection). Despite the success of global vaccination efforts, frequent reports of vaccine hesitance and refusal suggest that public health communications need improvement.

The chapter begins by acknowledging adverse events associated with COVID vaccination, including rare cases of anaphylaxis, GBS, and myocarditis. An inoculation-theoretic rationale is offered for this admission of vaccine risks: just as immune defenses mount when organisms are exposed to pathogens, so too …

The Roles Of Readily Releasable Stores Of Endolysosome Iron In The Pathogenesis And Treatment Of Alzheimer's Disease, Darius N.K Quansah

Theses and Dissertations

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized clinically as progressive decline in cognition and dementia. Pathologically, AD is characterized by the extracellular presence of senile plaques composed of accumulated amyloid beta (Aβ) proteins and intraneuronal accumulation of neurofibrillary tangles composed of hyperphosphorylated tau proteins. In addition to these pathological hallmarks, AD pathogenesis is characterized by increases in intracellular iron and reactive oxygen species (ROS) and the link between the two have been well described by Fenton’s chemistry. Endolysosomes appear to be affected very early in the onset of AD. Endolysosomes contain labile stores of iron which can be readily …

Ecological Dynamics In Beaver-Engineered Boreal Wetlands: Amphibian Phenology, Occupancy, And Aquatic Macroinvertebrate Communities, Talon Stammen

Theses and Dissertations

Boreal wetlands are ecologically rich yet vulnerable ecosystems shaped by hydrological dynamics, cold climate regimes, and landscape-scale disturbances. Among the most influential agents of change in these systems are beavers (Castor canadensis), whose engineering activities create a mosaic of lentic habitats at varying stages of ecological succession. This dissertation investigates the structure and dynamics of amphibian and aquatic macroinvertebrate communities across a beaver-influenced wetland landscape in Voyageurs National Park, Minnesota, USA.The first study (Chapter II) examines breeding phenology and detection patterns of boreal anurans using a combination of passive acoustic monitoring and visual encounter surveys at 25 wetlands over four …

Zaasijiwan: An Indigenized Health Communication Framework For American Indian And Alaska Native Communities, Jennifer Wolf

Theses and Dissertations

The Zaasijiwan Framework represents an Indigenized health communication model developed to enhance the cultural relevance, trust, and effectiveness of public health messaging for American Indian and Alaska Native (AI/AN) communities. This qualitative study integrated Indigenous and Western public health knowledge to inform the development of the framework. A comprehensive literature review and two rounds of key informant interviews with health communication professionals informed the design of the framework. Findings emphasized the importance of community co-creation and strengths-based narratives, along with other framework elements, in overcoming medical mistrust and improving health outcomes. The final framework offers public health professionals, Tribal, and …

Knocking On Resistance’S Door: Investigating The Spread And Drivers Of Kdr Mutations In Northern California Culex Tarsalis, Esther Blankenship-Cutshall

University of the Pacific Theses and Dissertations

Vector-borne diseases are an increasingly relevant threat to public health as climate change alters the ecology of vector populations in relation to humans. One key to combating vector-borne disease is using pyrethroid insecticides against mosquito populations. However, wild mosquito populations have exhibited resistance to those key pyrethroids. One resistance mechanism under investigation is the altering of the voltage-gated sodium channel, which is associated with the genetic mutations known as kdr. The prevalence and history of kdr mutations has been investigated in some populations of Culex pipiens, however, it is unknown in northern California Culex tarsalis populations. This study aims to …

Social Connection And Disability: A Longitudinal Experimental Study Of Intervention Effectiveness And Moderators, Krys Standley

Graduate Student Theses, Dissertations, & Professional Papers

Background: Social disconnection is an epidemic-level problem that is exacerbated for people with disabilities. There is a pressing need for theory-based research to illuminate the factors that contribute to effective interventions for improving social connection in this population.

Objectives: The objectives of this study were 1) to test the hypothesis that the Peer Collective, a six-week, online, group-based intervention centered on social support topics, would result in increased levels of social connection among community-dwelling adults with any types of disabilities and 2) to examine potential moderating effects in this hypothesized relationship.

Method: A longitudinal intervention study design with random assignment …

Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy, Robert Patrick Richter

All ETDs from UAB

Sepsis remains one of the most frequent causes of mortality and life-altering morbidity in humans of all ages globally. Though sepsis pathobiology is incompletely understood, it is clear that a unifying feature of all sepsis phenotypes is systemic vascular endotheliopathy and damage to the luminal glycocalyx of endothelial cells, or eGC, that leads to organ injury. While prior work has established that heparan sulfate (HS) is an especially important eGC constituent that helps regulate a host of endothelial cell (EC) functions, its role in promoting endotheliopathy during sepsis has not been fully characterized. Additionally, previous studies in the context of …

Molecular Interactions Between The Shellfish Pathogen Vibrio Coralliilyticus Re22 And The Probiont Phaeobacter Inhibens S4sm, Jessica Coppersmith

Open Access Dissertations

Oyster larvae aquaculture is an important industry, both economically and environmentally, helping to create sustainable food systems by supplying seed oysters to farms, and also to restoration projects aimed at building coastal resilience and improving water quality by rejuvenating wild populations. However, oyster larvae are highly susceptible to rapid mortality events, crashes, which can seriously impact the industry. One source of these crashes in hatchery systems is vibriosis, caused by pathogenic species of Vibrio bacteria that are ubiquitous in temperate coastal waters, and with rising surface water temperatures their prevalence and virulence are increasing. To prevent these larval crashes from …

Prevalence Of Insecticide Resistance Gene In Aedes Albopictus Populations Of Central Illinois, Merylann Akinyi Ochieng

Masters Theses

The Asian tiger mosquito, Aedes albopictus, is a significant vector for diseases such as Dengue, Chikungunya, and Zika. Its increasing resistance to insecticides poses a critical challenge for vector control efforts. This study investigates knockdown resistance (kdr) mutations in the voltage-gated sodium channel (VGSC) genes, specifically V1016G and F1534C, which are associated with pyrethroid resistance. Aedes albopictus populations from Central Illinois were analyzed using allele-specific PCR techniques to address three primary objectives: (1) determining whether V1016G and F1534C mutations are present in these populations, (2) determining which mutation is more widespread, and (3) investigating how resistance gene …

Corrigendum: Phenotypic Variation In Disease Severity Among Hospitalized Pediatric Patients With Covid-19: Assessing The Impact Of Covid-19 In The Epico Study, María Camila Sossa-Alarcón, Mónica Paola Gutiérrez, Natalia Becerra, Luz Yessenia Ortegon, María Camila David, Melisa Naranjo Vanegas, Gabriela Friedrich, Pablo Vásquez-Hoyos, María Lucía Mesa-Rubio, Luis Miguel Navarro-Ramirez, Sergio Moreno-Lopez, Olga Lucía Baquero, Luz Marina Mejía, Juan Gabriel Piñeros, Sonia Restrepo-Gualteros, Carlos Álvarez-Moreno, Alejandro Díaz-Díaz, Iván Gutierrez-Tobar, Andrés Camilo Mesa, William Ricardo Bachiller Tuta, Clara Esperanza Galvis Diaz, Martha Africano, José Manuel Nieto, Paola Marsela Pérez Camacho, Claudia Beltrán-Arroyave, Rosalba Vivas Trochez, Irati Gastesi, Cinta Moraleda, Alfredo Tagarro García, Blanca Herrero, Lourdes Calleja, Carlos Grasa, Paula Rodriguez, Susana Melendo, Antoni Soriano-Arandes, Irene Gómez Pastrana, Sonsoles García García, Victoria Fumado, Andrea Ramírez Varela

Faculty, Staff and Student Publications

This corrects the article "Phenotypic Variation in Disease Severity Among Hospitalized Pediatric Patients With COVID-19: Assessing the Impact of COVID-19 in the EPICO Study", 1607246.

Development, Delivery, And Evaluation Of The Texas Epidemic Public Health Institute Infection Control Module Program 200 Series, Kayla E Ruch, Anabel Rodríguez, Janelle Rios

Faculty, Staff and Student Publications

Background: The Texas Epidemic Public Health Institute (TEPHI) aims to safeguard public health and the Texas economy by preparing for infectious disease outbreaks. The Infection Prevention and Control (IPC) Webinar series was created to offer free educational resources and continuing education for public health and healthcare personnel responsible for IPC programs in rural regions of Texas. The IPC 200 Series succeeds the founding IPC 100 Series established by the TEPHI Small Rural Healthcare Preparedness.

Methods: IPC registration and attendance data were collected through WebEx® and Microsoft Teams®, which also served as the platforms for module delivery. Learning assessments and post-module …

Diversity In United States Dementia Prevention Trials: An Updated Systematic Review Of Eligibility Criteria And Recruitment Strategies, Najoua Lazaar, Sabine E Van Beek, Awaale F Rirash, Janne M Papma, Jaime Perales-Puchalt, Ashley R Shaw, Eric D Vidoni, Sanne Franzen

Faculty, Staff and Student Publications

Introduction: Given the elevated dementia risk in underrepresented demographic groups in the USA - particularly in Latino and Non-Latino Black individuals compared to Non-Latino White individuals - it is vital that these groups are well-represented in dementia prevention research. Eligibility criteria and recruitment strategies may play a key role in promoting participant diversity. The aim of this review was to examine eligibility criteria and recruitment strategies in US dementia prevention trials in light of participant diversity.

Methods: A systematic review was conducted using Medline (including PubMed), Embase, Cochrane Library, and CINAHL. We explored the percent White participants for trials using …

Ai: A Path Forward In Education - Teachers’ Insights On Implementation, Challenges, And Future Innovations, Mercedes Cordoba Meeks

Theses and Dissertations

Artificial intelligence (AI) is a global phenomenon permeating the fabric of society and transforming the course of culture and commerce (Kishor et al., 2023; Moore, 2024). A review of the extant literature indicates that while many industries have seen significant innovations due to the infusion of AI, the field of education has witnessed a technological evolution inspired by AI-based tools and strategies (Bessen, 2018; W. M. Lim et al., 2023). Artificial Intelligence in Education (AIED) has a history that parallels the development of AI. AIED has shown steady growth and influence in educational programs around the world, with the growth …

Medical Students’ Disaster-Specific Self-Efficacy And Willingness To Respond Following An Introductory Preparedness Training, Brooke Wagner, Libby Washburn, Joseph D Visker, Carol Cox

Health Professions Education

Purpose.

The purpose of this cross-sectional study was to examine medical students’ disaster self-efficacy and willingness to respond to disasters before and after attending an introductory disaster preparedness training program during fall 2023.

Method.

Medical students (eight Year 1 and 18 Year 2) attending a one-day introductory disaster preparedness program that focused on an all-hazard approach and used lecture and applied scenario practice instruction were surveyed pre-post program using a written, four-section questionnaire on their disaster-specific self-efficacy and willingness to respond to disasters. Statistical analyses were conducted using IBM SPSS Statistics (v29) and primarily consisted of descriptive statistics (frequencies and …

Evaluation Of A Multidrug-Resistant Acinetobacter Baumannii Outbreak In A Large Community Hospital And Long-Term Acute Care Hospital, Evan Lawson, Spencer H. Durham, Kelsey Ivey, Jonathan Edwards, Madeline Belk

UAB Huntsville Research Day - All Presentations

2025 research poster

Breathless Battle: Navigating Immunotherapy Complications In Stage 4 Lung Cancer, Brittany Fennell, Megan Roberts, Roger D. Smalligan

UAB Huntsville Research Day - All Presentations

No abstract provided.

Think Twice: A Case Of Syphilitic Endophthalmitis, Ahmed Qaedi, Sarika Mullapudi, Tarek Persaud, Ali Hassoun

UAB Huntsville Research Day - All Presentations

No abstract provided.

Strep Strikes: A Case Of Group A Streptococcal Bacteremia And Second Trimester Pregnancy Loss, Jalen Spain, Racquel Mccrary, Miranda Worley, Rebecca Daugherty

UAB Huntsville Research Day - All Presentations

No abstract provided.

In Through The Side Door: Anti-Asian Nativism, U.S. Immigration, And Foreign Policy—A Legal History And Case Study, Deenesh Sohoni, Vivian E. Hamilton, Chinua Thelwell

Faculty Publications

The 19th- and early 20th-centuries were marked by pervasive anti-Asian sentiment, and antipathy towards people of color more generally. Giving legal effect to the anti-Asian nativism prevalent at the time, U.S. policies prohibited most Asian immigration and naturalization. In particular, immigration laws sought to exclude Asian laborers and working-class immigrants from entry. During the same period, however, the federal government determined that other Asian visitors—especially Chinese government officials, merchants, religious leaders, and students—could be useful in advancing U.S. political and economic interests abroad. Thus, in marked contrast to its inhospitable treatment of their working-class counterparts, U.S. policy facilitated the entry …

Understanding Women's Access To And Utilization Of Syringe Service Programs, Annelisa E. Swiersz

Honors Undergraduate Theses

As of 2020, 138 million Americans ages 12 and over reported illicit drug use in their lifetime, with over 3 million of those people injecting drugs. There are risks for all people who use drugs, but people who inject drugs (PWID) pose specific risks such as hepatitis B, hepatitis C, and human immunodeficiency virus (HIV), with women who inject drugs (WWID) facing even more risks. WWID involved in sex work have a higher risk of HIV transmission and lack access to sterile injection devices and sexual and reproductive health services. To address these risks, syringe service programs (SSPs) were developed …

Tribal Health Self-Determination: The Role Of Tribal Health Systems In Actualizing The Highest Attainable Standard Of Health For American Indians And Alaska Natives, Vanessa Ann Racehorse

Publications

In this Article, I explore the concept of Tribal self-determination in the context of systems that serve American Indian and Alaska Native communities. I investigate the vast health disparities that exist in Tribal communities, as well as the history and current legal framework for the provision of health care in Indian Country. Part of this discussion also provides information on the federal laws and policies that have fractured the traditional lifeways of Native communities and contributed to the disparate health outcomes that now exist. I also provide background on the fundamental federal laws and policies, particularly the Indian Self-Determination and …

A Transformational Agenda For National Security, Maryam Jamshidi

Publications

Past efforts to "reimagine" national security in legal scholarship have largely avoided systematic engagement with the foundational assumptions and presumptions of the field. Challenging and critiquing those assumptions is, however, necessary to producing scholarly work that reimagines, rather than reproduces, status quo approaches to U.S. national security. This Article presents an agenda for reimagining national security through legal scholarship, which is premised on the view that challenging the national security status quo should be part of those efforts. In doing so, this agenda explores seven premises central to how U.S. national security is currently conceived of, practiced, and implemented. Moving …

Displaying Wastewater Surveillance Data: An Ethics Framework, Govind Persad, Anne Barnhill, Douglas Mackay

Publications

No abstract provided.

Poor Cancer Prevention And Detection In Zimbabwe, Kenyon Chipman

Ballard Brief

In the wake of the AIDS/HIV epidemic, rates of non-communicable diseases such as cancer have increased. Although AIDS/HIV and other cancer-associated communicable diseases like HPV are on the decline, these diseases have laid the foundation for the rising cancer epidemic in Sub-Saharan Africa. While infectious diseases remain major contributors to the development of cancer, poor prevention and detection of cancer acts as the central catalyst in the nation’s inflated morbidity and mortality rate. A general lack of knowledge about the basics of cancer for both patients and health professionals, along with the barriers to preventative and detective resources and services, …