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Evaluation Of Chicken Serum And Chicken Egg Yolk As Novel Supplements For The In Vitro Cultivation Of Mycoplasma Hyorhinis, Yi-Chia Li, Sin-Hang Ma, Wei-Hao Lin, Chao-Nan Lin, Ming-Tang Chiou Dec 2025

Evaluation Of Chicken Serum And Chicken Egg Yolk As Novel Supplements For The In Vitro Cultivation Of Mycoplasma Hyorhinis, Yi-Chia Li, Sin-Hang Ma, Wei-Hao Lin, Chao-Nan Lin, Ming-Tang Chiou

The Thai Journal of Veterinary Medicine

Mycoplasma hyorhinis is a significant pathogen in swine, yet its fastidious nutritional requirements present challenges for in vitro cultivation. Conventional supplements like horse serum (HS) often suffer from batch variability and potential inhibitors. This study aimed to evaluate chicken serum (CS) and chicken egg yolk (CY) as novel alternatives to develop a reliable cultivation method for M. hyorhinis. Five clinical isolates were cultured for 10 days in a basal medium supplemented with CS or CY at 10%, 20%, or 30%, with 30% HS as the control. Growth was quantified daily using a Color Changing Unit (CCU) assay. CS supported …


Hubungan Faktor Iklim, Faktor Polutan Dan Faktor Sosioekonomi Terhadap Proporsi Pneumonia Balita Provinsi Dki Jakarta Tahun 2013 – 2022, Fayza Chairunnisa Permana, Zakianis Zakianis, Laila Fitria, Erni Pelita Fitratunnisa Dec 2025

Hubungan Faktor Iklim, Faktor Polutan Dan Faktor Sosioekonomi Terhadap Proporsi Pneumonia Balita Provinsi Dki Jakarta Tahun 2013 – 2022, Fayza Chairunnisa Permana, Zakianis Zakianis, Laila Fitria, Erni Pelita Fitratunnisa

Jurnal Nasional Kesehatan Lingkungan Global

In 2022, the Province of DKI Jakarta ranked fourth with the highest coverage of pneumonia in toddlers (53.2%), exceeding Indonesia's toddler pneumonia coverage (38.78%). Pneumonia is influenced by various risk factors, including environmental factors such as climate and weather conditions as well as air pollution, and social and behavioral factors such as toddler characteristics, parental socioeconomic status, and access to health care services. This study aimed to analyze the relationship between climate factors (air temperature, relative humidity, rainfall, and air pressure), pollutant factors (PM10, SO2, CO, O3, NO2), and parents' socioeconomic …


Environmental Health Risks To Children In Sub-Saharan Africa: A Scoping Review Of Evidence And Gaps In Global Interventions, Tadius C. Chitambwe, Dewi Susanna Dec 2025

Environmental Health Risks To Children In Sub-Saharan Africa: A Scoping Review Of Evidence And Gaps In Global Interventions, Tadius C. Chitambwe, Dewi Susanna

Jurnal Epidemiologi Kesehatan Indonesia

Sub-Saharan Africa’s (SSA) children experience a disproportionate burden of environmental health risks, contributing to over half of global under-five deaths despite representing only 27% of live births 1. This scoping review synthesised evidence from sixty-seven (67) eligible studies (2010–2025) to map out environmental exposures affecting children (0–18 years) in Sub-Saharan Africa, and to identify gaps in global interventions. Included studies focused on children (0-18 years) in SSA, addressed one or more of the four predefined environmental exposure domains (air pollution, WASH, toxic chemicals, climate-related risks), and reported on child health outcomes or interventions. Guided by the PRISMA and Arksey …


Kejadian Luar Biasa Gondongan Di Sd Islam X Samarinda, 2024, Rudy Agus Riyanto, Irfansyah Baharuddin Pakki, Mela Sabena, Meli Pasiakan, Erlina Erlina, Rima Andriani Dec 2025

Kejadian Luar Biasa Gondongan Di Sd Islam X Samarinda, 2024, Rudy Agus Riyanto, Irfansyah Baharuddin Pakki, Mela Sabena, Meli Pasiakan, Erlina Erlina, Rima Andriani

Jurnal Epidemiologi Kesehatan Indonesia

Mumps outbreaks are a public health issue that still frequently occur in elementary school settings, particularly among children with low immunization coverage. Therefore, a comprehensive epidemiological understanding is needed as a basis for control. This research aims to describe the epidemiological picture and causative factors of the mumps outbreak that occurred at Islamic Elementary School X in Samarinda City in 2024, using a case series design. The outbreak occurred from April to October 2024, while epidemiological data collection and case verification were conducted from December 2nd to 8th, 2024. The analysis uses surveillance data, field observations, and questionnaires administered to …


The Use Of Local Materials For The Interior Quality Of Swahili Building Design In Tanzania, Luiana Makundi, Jacob Lutta Dec 2025

The Use Of Local Materials For The Interior Quality Of Swahili Building Design In Tanzania, Luiana Makundi, Jacob Lutta

Tanzania Journal of Engineering and Technology (TJET)

Swahili architecture in Tanzania is recognized by spatial capacity to adapt environmental changes. This research explores the role of locally available materials in shaping the interior quality by focusing on functional, aesthetic appeal and supporting sustainable environment. A mixed-methods approach was applied which, involves field surveys, case study and interviews with different local professionals in building industry. Dar-es-Salaam was used as a case study area that was critically analysed to identify construction practices and applications of local materials in building interior spaces. A particular focus was placed on materials durability, aesthetic, ecological, environmental balance and thermal efficiency which seems to …


The Therapeutic And Physiological Effects Of Citrus Peel Extraction On Helicobacter Pylori Bacteria, Sara Saeb Rasheed, Rawnaq Z. Fadhil, Marwah Amer Qamandar, Salah M.M. Al-Chalabi Dec 2025

The Therapeutic And Physiological Effects Of Citrus Peel Extraction On Helicobacter Pylori Bacteria, Sara Saeb Rasheed, Rawnaq Z. Fadhil, Marwah Amer Qamandar, Salah M.M. Al-Chalabi

Al-Esraa University College Journal for Medical Sciences

The antibiotic resistance has emerged as a growing international concern affecting not only human health but also the environment, animal population, and global economy. The increasing prevalence of antibiotic resistance poses a serious and escalating threat to public health. This problem is further exacerbated by the limited development of new antibiotic, high production costs, and risks about its side effects. Identifying novel antibiotic agents is crucial for managing fungal and bacterial infection. Consequently, numerous natural compound have been investigated as potential alternative therapies. Plant extracts are valuable source of bioactive compounds and represent a promising strategy to control pathogenic microorganisms. …


Mathematical Analysis And Numerical Simulation Of A Fractional-Order Sir-Si Model For Malaria Transmission Dynamics, Gassan A. M. O. Farah, Abdulaziz Y. A. Mukhtar, Kailash C. Patidar Dec 2025

Mathematical Analysis And Numerical Simulation Of A Fractional-Order Sir-Si Model For Malaria Transmission Dynamics, Gassan A. M. O. Farah, Abdulaziz Y. A. Mukhtar, Kailash C. Patidar

Mathematical Modelling and Numerical Simulation with Applications

This study investigates the complex transmission dynamics of malaria, a critical global health challenge, with a focus on the African continent. We introduce a novel approach that employs Fractional Differential Equations (FDEs) to advance the understanding of malaria spread and control. Specifically, we develop a new SIR-SI model using the Caputo fractional operator, which captures the memory effects and time-delay characteristics inherent in real-world epidemiological systems. A detailed analysis of the model's solvability and uniqueness is conducted using fixed-point theory. To obtain an analytical solution, the system is solved via the Laplace transform method, with solutions expressed in closed form …


Invasive Candidiasis In Critically Ill Patients: Fundamental Concepts And Future Directions, María Alejandra Pérez, Wesley J Hoffmann, J Christian Pérez, Max W Adelman Dec 2025

Invasive Candidiasis In Critically Ill Patients: Fundamental Concepts And Future Directions, María Alejandra Pérez, Wesley J Hoffmann, J Christian Pérez, Max W Adelman

Faculty, Staff and Student Publications

Topic importance: Invasive candidiasis (IC) is a common complication in patients in ICUs. IC can be divided into bloodstream infections (candidemia) and deep-seated infections. Candida infections are associated with high mortality and longer hospital stays. Moreover, the emergence of Candida auris and other species prone to cause ICU outbreaks highlights the importance of this pathogen.

Review findings: Candidemia represents about 20% of bloodstream infections in ICU patients, whereas intraabdominal candidiasis, the most common form of deep-seated infection, predominantly affects surgical ICU patients. Regarding species distribution, Candida albicans is the most common species; however, non-albicans species have become more prevalent in …


Karanasan Ng Piling Pamilyang Pilipino Sa Panahon Ng Pandemya: Alaala Ng Enhanced Community Quarantine Sa Metro Manila, Glenda D. Salorsano Dec 2025

Karanasan Ng Piling Pamilyang Pilipino Sa Panahon Ng Pandemya: Alaala Ng Enhanced Community Quarantine Sa Metro Manila, Glenda D. Salorsano

Social Sciences and Development Review

The global spread of COVID-19 has become a worldwide phenomenon. Every country faced different challenges brought by the pandemic in which highlighted the strengths and weaknesses of each nation in combating the virus. It not only became a widespread blow to the health sector but also paved the way for the revelation of other social aspects that need attention. This occurrence allowed the concrete identification of other deficiencies in crucial sectors of society that are associated with pandemic response. These include infrastructure, public transportation, public safety, human rights, and access to sufficient and proper food for every family, and financial …


Antibiotic Use And Mdr-Tb Management In Primary Health Centers: A District-Wide Survey From Karnataka, India, Bilkees Javeed, Junaid Mushtaq, S J Nagaveni, Arunkumar K Dec 2025

Antibiotic Use And Mdr-Tb Management In Primary Health Centers: A District-Wide Survey From Karnataka, India, Bilkees Javeed, Junaid Mushtaq, S J Nagaveni, Arunkumar K

Indian Journal of Health Sciences and Biomedical Research KLEU

Antimicrobial resistance (AMR) poses a critical threat to global health, with India experiencing one of the highest burdens of resistant infections. Primary Health Centers (PHCs) serve as frontline facilities where Medical Officers and Pharmacists play crucial roles in antimicrobial stewardship. However, comprehensive data on antibiotic utilization patterns and multidrug-resistant tuberculosis (MDR-TB) management in Karnataka’s PHCs remain limited. This study aimed to characterize antibiotic prescribing and dispensing practices, assess AMR knowledge, and evaluate MDR-TB management across all PHCs in Gadag District. A cross-sectional survey employing complete enumeration was conducted across all 42 PHCs in Gadag District, Karnataka. All Medical Officers (n …


The Role Of Ai In Addressing The United Nations Sustainable Development Goals (Sdgs): A Comprehensive Survey, Walid Abdullah, Muhammad Nawaz, Basma Nasir, Muhammad Javed Ramzan Dec 2025

The Role Of Ai In Addressing The United Nations Sustainable Development Goals (Sdgs): A Comprehensive Survey, Walid Abdullah, Muhammad Nawaz, Basma Nasir, Muhammad Javed Ramzan

Sustainable Machine Intelligence Journal

Artificial Intelligence (AI) emerges as a transformative tool in addressing global challenges, particularly in achieving the United Nations Sustainable Development Goals (SDGs). This paper provides a comprehensive survey of how AI technologies contribute to addressing global challenges across social, economic, and environmental domains. By enabling advanced data analysis, predictive modeling, and automation, AI offers innovative solutions across sectors such as poverty reduction, healthcare, quality education, sustainable cities, climate action, and the protection of life on land and below water. Special attention is given to practical, real-world examples where AI enables more efficient resource management, predictive analytics, environmental monitoring, and data-driven …


Perspectives On Implementing Environmentally Sustainable Practices In Cataract Surgeries: Interviews Of Administrative And Frontline Healthcare Workers, Daniel Parra, Brooke Sherry, Emma Pak, Lauren Taylor, Erin S. Rogers, Sarah E. Hochman, Maria De Los Angeles Ramos Cadena, Joel S. Schuman, Christina R. Prescott, Cassandra L. Thiel Dec 2025

Perspectives On Implementing Environmentally Sustainable Practices In Cataract Surgeries: Interviews Of Administrative And Frontline Healthcare Workers, Daniel Parra, Brooke Sherry, Emma Pak, Lauren Taylor, Erin S. Rogers, Sarah E. Hochman, Maria De Los Angeles Ramos Cadena, Joel S. Schuman, Christina R. Prescott, Cassandra L. Thiel

Wills Eye Hospital Papers

BACKGROUND: Healthcare is responsible for 8.5% of greenhouse gas emission in the United States. Physicians are becoming increasingly concerned about the climate crisis, particularly in the field of ophthalmology where there is a growing body of literature related to sustainability. Although emissions of cataracts surgery, one of the most performed surgical procedures in the world, have been quantified, modifications to practice have yet to be made. This study aims to uplift the perspectives of a diverse set of healthcare workers on implementing environmentally sustainable practices in the cataract surgery setting.

METHODS: 16 semi-structured interviews were conducted with professionals working in …


Echocardiographic Alterations After Administration Of Azithromycin In Donkeys: An Experimental Crossover Study, Mohamed Marzok, Maged El-Ashker, Mahmoud Kandeel, Adel Almubarak, Khalid Alkhodair, Alshimaa Farag, Hussam Ibrahim, Sabry El-Khodery, Hussein Babiker Dec 2025

Echocardiographic Alterations After Administration Of Azithromycin In Donkeys: An Experimental Crossover Study, Mohamed Marzok, Maged El-Ashker, Mahmoud Kandeel, Adel Almubarak, Khalid Alkhodair, Alshimaa Farag, Hussam Ibrahim, Sabry El-Khodery, Hussein Babiker

The Thai Journal of Veterinary Medicine

Cardiotoxicity and impairment of cardiac function are mostly diagnosed by echocardiography and based on objective metrics of cardiac function. The aim of the present study is to investigate the effect of azithromycin on the echocardiographic characteristics in healthy donkeys. Ten healthy donkeys were enrolled in a prospective crossover study. The study included two groups: (1) a placebo (normal saline, NaCl 0.9%), and (2) azithromycin (at a dose of 5 mg/kg body weight). A 2.0-3.9 MHz phased-array transducer was used for echocardiographic examination. Echocardiographic examinations were performed for donkeys before treatment (T0) and at 15, 30, 60, 90, 120, 180, and …


From Plague To Cholera: The Prevention And Treatments Of Cholera In Thailand, 1820–1959, Suwasadee Photpun Dec 2025

From Plague To Cholera: The Prevention And Treatments Of Cholera In Thailand, 1820–1959, Suwasadee Photpun

Journal of Letters

This article aims to explore the history of cholera in Thailand from 1820 to 1959, focusing on disease prevention and the evolving treatment methods for cholera patients across different historical periods. The article argues that knowledge about pathogens and the discovery of Vibrio cholerae as the cause of cholera did not lead to significant changes in cholera prevention and treatment methods before the mid-20th century. Methods like maintaining hygiene, implementing quarantine, and treating the disease with Western medicine and intravenous saline infusions were already known and utilized before the acceptance of germ theory and before the discovery of bacteria as …


The Dynamic Among The Producer, Consumer, And Predator In The Presence Of Fear, Hunting Cooperation, And Anti-Predator Behavior, Muslim Saad Jabbar, Raid Kamel Naji Dec 2025

The Dynamic Among The Producer, Consumer, And Predator In The Presence Of Fear, Hunting Cooperation, And Anti-Predator Behavior, Muslim Saad Jabbar, Raid Kamel Naji

Baghdad Science Journal

In general, the dynamic interactions that form the relationships between predators and prey within a food chain depend heavily on fear, hunting cooperation, and anti-predator defenses. These elements support species’ survival in their particular habitats, balance the ecosystem, and control the numbers of predators and prey. Therefore, a three-species food chain system consisting of producer-consumer-predator, which plays a crucial role in ecological dynamics, has been formulated mathematically. The objective is to investigate the influence of fear, hunting cooperation, and anti-predators on the dynamic behavior of the food chain system. Two types of functional responses have been utilized. The characteristics of …


Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇ Dec 2025

Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇

Turkish Journal of Chemistry

Human serum albumin (HSA) is a ubiquitous, multifunctional protein responsible for the systemic distribution of both endogenous metabolites and exogenous pharmaceuticals. Its inherent properties, particularly its ability to seep into tissues and its multiple ligand-binding sites, have rendered HSA an attractive vehicle for nanoparticle-based drug delivery systems, particularly for cancer targeting. In this study, we present high-resolution crystallographic data revealing two distinct dimerization patterns of HSA (Protein Data Bank [PDB] ID: 9V61) obtained under high-concentration crystallization conditions, along with results from dipyridamole docking. Both dimer types demonstrate extensive interface areas and a significant number of electrostatic interactions. Comparative analysis with …


A Pilot Qualitative Study To Better Understand The Factors Related To Suicides And Inform Public Health Action Across A Predominantly Coastal And Rural Area: Cornwall, Southwest Of England: International Journal Of Environmental Research And Public Health, Paula Chappell, Jane Horrell, Kerryn Husk, Beth Simons, Richard A. Sharpe Dec 2025

A Pilot Qualitative Study To Better Understand The Factors Related To Suicides And Inform Public Health Action Across A Predominantly Coastal And Rural Area: Cornwall, Southwest Of England: International Journal Of Environmental Research And Public Health, Paula Chappell, Jane Horrell, Kerryn Husk, Beth Simons, Richard A. Sharpe

Peninsula Medical School

Background: Better understanding factors leading to suicide and prevention opportunities is a global public health priority. This qualitative pilot study tested whether reviewing inquest recordings could generate insights during COVID-19 and inform public health prevention programmes across a predominantly rural and coastal area where there are significant health inequalities. Methods: Fifty-five inquest recordings reached a suicide conclusion between March 2020 and January 2021. Stratified sampling was used to obtain two samples from each month. Template analysis was employed to thematically analyse data from 30 inquests. Results: Risk factors during this period were social isolation, anxiety, difficulty in routine creation and …


Association Of Abo Blood Groups With Dengue Fever And Its Severity: A Study In Surabaya, Indonesia, Sulistiawati Sulistiawati, Linda Dewanti, Ronald Pratama Adiwinoto, Raissa Manika Purwaningtias, Bilqis Inayatillah, Jan Nouwen Dec 2025

Association Of Abo Blood Groups With Dengue Fever And Its Severity: A Study In Surabaya, Indonesia, Sulistiawati Sulistiawati, Linda Dewanti, Ronald Pratama Adiwinoto, Raissa Manika Purwaningtias, Bilqis Inayatillah, Jan Nouwen

Journal of Health Research

Background: Indonesia, a dengue-endemic country, has high morbidity and mortality rates. Dengue infection manifestations vary from asymptomatic to mild to severe. One of the risk factors for infection that plays a role in this severity is blood type. A better understanding of the risk factors for dengue infection is required to prevent and control it.

Methods: This analytical observational cross-sectional study was conducted at three hospitals in Surabaya from March to May 2013. Consecutive sampling included 95 patients aged >12 years with confirmed dengue infection (IgM/IgG positive) and without comorbid severe illness. Data were collected using questionnaires, interviews, and checklists, …


Mental Health First Aid Certification's Impact On Filipino Nurses' Ability To Increase Personal Help-Seeking Behaviors, Self-Awareness Of Health Changes, And Improved Self-Connection, Maria Elena Holguin, Brenda Marshall, Faith Atte, Katherine J. Roberts Dec 2025

Mental Health First Aid Certification's Impact On Filipino Nurses' Ability To Increase Personal Help-Seeking Behaviors, Self-Awareness Of Health Changes, And Improved Self-Connection, Maria Elena Holguin, Brenda Marshall, Faith Atte, Katherine J. Roberts

School of Nursing Faculty Scholarship and Creative Works

Background

Post COVID-19, almost 50% of nurses reported severe depression, and over 30% moderate to severe anxiety. Nurses from minority racial and ethnic backgrounds, including Filipino nurses, accounted for more than 54% of COVID-related deaths, despite comprising only 24.1% of the nursing workforce. Filipino nurses, making up only 1% of the U.S. population, comprise 4.5 % of the nursing workforce and face significant barriers to seeking mental health services, including stigma, a sense of shame, and adherence to cultural values that view mental illness as unacceptable.

Aim 

To assess the impact of Mental Health First Aid (MHFA) certification among Filipino …


Antifungal Activity Of Nutmeg Mace (Myristica Fragrans Houtt) Ethanol Extract Against Candida Spp., Muhammad Akbar Yandji, Eka Astuty, Fitri Kadarsih Bandjar Dec 2025

Antifungal Activity Of Nutmeg Mace (Myristica Fragrans Houtt) Ethanol Extract Against Candida Spp., Muhammad Akbar Yandji, Eka Astuty, Fitri Kadarsih Bandjar

Folia Medica Indonesiana

Candida infections are increasingly common worldwide and represent one of the leading causes of death after cardiovascular disease. There are three types of candida that often infect humans, namely Candida albicans, Candida tropicalis and Candida parapsilosis. In the standard treatment used, immunity and side effects of treatment have been found. Therefore, other treatment options are needed, one of which is by using mace (Myristica fragrans Houtt) which is a native plant of Maluku and has secondary metabolite compounds that can be antifungal agents. This study aims to test the ability of ethanol extract of mace nutmeg ( …


Clinical Outcomes Of Electrosurgery For Management Of Giant Condyloma Acuminata: A Systematic Review, Fortunia Mona Eviani, Maureen Miracle Stella, Arief Budiyanto, Satiti Retno Pudjiati, Alessandro Alfieri Dec 2025

Clinical Outcomes Of Electrosurgery For Management Of Giant Condyloma Acuminata: A Systematic Review, Fortunia Mona Eviani, Maureen Miracle Stella, Arief Budiyanto, Satiti Retno Pudjiati, Alessandro Alfieri

Folia Medica Indonesiana

Giant condyloma acuminata (GCA) is a rare sexually transmitted disease that is locally aggressive with a high recurrence rate. Electrosurgery is a minimally invasive procedure that may be less expensive, quicker, and safer than conventional surgery. This study aimed to review the management of GCA with electrosurgery. We followed PRISMA 2020 guidelines to search and retrieve literature in the following databases: PubMed, ProQuest, Taylor & Francis, ScienceDirect, JSTOR, and SAGE without time restrictions. The study inclusion criteria were original articles that studied the outcome of electrosurgery in GCA. The authors evaluated the risk of bias using the Joanna Briggs Institute …


Modelling The Impact Of Multiple Control Strategies On The Spread Of Phyllody Disease In Sesame, Augustino I. Msigwa, Furaha M. Chuma Dec 2025

Modelling The Impact Of Multiple Control Strategies On The Spread Of Phyllody Disease In Sesame, Augustino I. Msigwa, Furaha M. Chuma

Tanzania Journal of Science

Phyllody disease, caused by phytoplasma and transmitted by insect vectors such as leafhoppers, poses a serious threat to the productivity of sesame (Sesamum indicum) as it has caused substantial yield and oil-quality losses worldwide, with documented seed-yield reductions ranging from 38% to as high as 80% in severe outbreaks, particularly in Africa and India. Understanding phyllody dynamics is therefore critical to safeguard yields and trade. While some modeling efforts exist for sesame phyllody (for example, statistical and prediction-focused approaches), mechanistic transmission models (SEIR) assessing its full impact remain scarce. This study therefore develops and analyses impact of multiple control strategies …


Simulation Based Model For Canine Distemper Virus In Prey-Predator Dynamics, Mussa A. Stephano Dec 2025

Simulation Based Model For Canine Distemper Virus In Prey-Predator Dynamics, Mussa A. Stephano

Tanzania Journal of Science

This study investigates the dynamic interactions of a prey-predator ecosystem infected with Canine Distemper Virus (CDV), focusing on predation and disease transmission. A deterministic model, coupled with Monte Carlo simulations (MCS), employed to capture both stochastic variability and environmental fluctuations. The findings indicate that classical prey-predator cycles provide the baseline for population dynamics, but the introduction of CDV and environmental noise fundamentally alters system behavior. Initially, populations exhibit oscillations that gradually stabilize into dynamic equilibria. However, the disease persists within both prey and predator populations, suggesting endemicity rather than extinction. Predation plays a dual role in disease dynamics, while it …


Mathematical Modeling Of Awareness-Driven Interventions For Gender-Based Violence Control In A Closed Population, Furaha M. Chuma, Edward K. Ngailo, Zubeda S. Mussa Dec 2025

Mathematical Modeling Of Awareness-Driven Interventions For Gender-Based Violence Control In A Closed Population, Furaha M. Chuma, Edward K. Ngailo, Zubeda S. Mussa

Tanzania Journal of Science

Gender-based violence (GBV) remains a critical global health issue with profound social, economic, and psychological implications. Despite concerted efforts to address this challenge, traditional intervention approaches often fall short of effectively mitigating its prevalence. In recent years, there has been growing recognition of the potential impact of awareness-based interventions in addressing various social and health crises. This paper introduces a modeling framework to explore the efficacy of awareness-based interventions in influencing the dynamics of the GBV epidemic within a closed population. A detailed sensitivity analysis, utilizing a normalized sensitivity index method, reveals that the violence transfer rate between perpetrators and …


Phospholipid Scramblase 1 (Plscr1) Regulates Interferon-Lambda Receptor 1 (Ifn-Λr1) And Ifn-Λ Signaling In Influenza A Virus (Iav) Infection, Alina Xiaoyu Yang, Lisa Ramos-Rodriguez, Parand Sorkhdini, Dongqin Yang, Carmelissa Norbrun, Sonoor Majid, Sanghyun Lee, Yong Zhang, Michael Holtzman, David F Boyd, Yang Zhou Dec 2025

Phospholipid Scramblase 1 (Plscr1) Regulates Interferon-Lambda Receptor 1 (Ifn-Λr1) And Ifn-Λ Signaling In Influenza A Virus (Iav) Infection, Alina Xiaoyu Yang, Lisa Ramos-Rodriguez, Parand Sorkhdini, Dongqin Yang, Carmelissa Norbrun, Sonoor Majid, Sanghyun Lee, Yong Zhang, Michael Holtzman, David F Boyd, Yang Zhou

2020-Current year OA Pubs

Phospholipid scramblase 1 (PLSCR1) is an interferon-stimulated gene (ISG) that has several known anti-influenza functions. However, the mechanisms in relation to its expression compartment and enzymatic activity have not been completely explored. Moreover, only limited animal models have been studied to delineate its role at the tissue level in influenza infections. Our results showed that influenza A virus (IAV)-infected


Cytomegalovirus Associated Enterocolitis And Skin Eruption: A Pediatric Case Misdiagnosed As Acute Appendicitis, Zeynep Busra Balik, Gulsen Akoglu Dec 2025

Cytomegalovirus Associated Enterocolitis And Skin Eruption: A Pediatric Case Misdiagnosed As Acute Appendicitis, Zeynep Busra Balik, Gulsen Akoglu

Journal of Pediatric Infectious Diseases

We present a case of an immunocompetent 2-year-old boy, with cytomegalovirus-associated enterocolitis and petechial skin eruption, initially misdiagnosed as acute appendicitis. Despite abdominal pain, diarrhea and a rash for 15 days, diagnostic laparoscopy revealed no surgical pathology. Dermatological examination identified perifollicular petechiae, leading to a diagnosis of cytomegalovirus infection, which was confirmed by serology. This case emphasizes the importance of considering viral infections in pediatric patients with gastrointestinal and dermatological symptoms. It also highlights the diagnostic value of cutaneous findings in cytomegalovirus infection.


Symptom Spectrum And Risk Factors For Fever In Pediatric Patients With Omicron Infection: A Prospective Observational Study, Jiande Chen, Qiuyu Tang, Dong Wang, Shuhua Yuan, Jilei Lin, Fengquan He, Yong Yin Dec 2025

Symptom Spectrum And Risk Factors For Fever In Pediatric Patients With Omicron Infection: A Prospective Observational Study, Jiande Chen, Qiuyu Tang, Dong Wang, Shuhua Yuan, Jilei Lin, Fengquan He, Yong Yin

Journal of Pediatric Infectious Diseases

Objective: The omicron variant of coronavirus disease 2019 (COVID-19) has caused a global epidemic in 2022. Our aim was to investigate the symptom spectrum and risk factors for fever in pediatric patients with omicron infection. Methods: From April 8, 2022, to May 17, 2022, this prospective observational study included pediatric patients who attended the child-parent sections of the Fangcang shelter hospitals with laboratory-confirmed COVID-19. Patient data were collected from questionnaires. The risk factors for prolonged fever and high fever were identified by univariate and multivariate analyses. Results: In total, 1,541 pediatric patients were included. The most common symptoms associated with …


Lipid Biomarkers Predict Pneumonia Risk In Children With Influenza-Mycoplasma Co-Infections: A Retrospective Cohort Study, Kai-Jing Zhang, Xin-Feng Zhao, Xiao-Juan Lv, Xiao-Hui Huang, Jing Huang, Yan-Yan Zhu Dec 2025

Lipid Biomarkers Predict Pneumonia Risk In Children With Influenza-Mycoplasma Co-Infections: A Retrospective Cohort Study, Kai-Jing Zhang, Xin-Feng Zhao, Xiao-Juan Lv, Xiao-Hui Huang, Jing Huang, Yan-Yan Zhu

Journal of Pediatric Infectious Diseases

Objective: This study evaluates the prognostic value of high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) levels for pneumonia risk in children co-infected with influenza and Mycoplasma pneumoniae (MP). Methods: We retrospectively analyzed 248 children with influenza-MP co-infection (January 1, 2020–October 30, 2024). Participants were grouped into pneumonia (P, n=195) and non-pneumonia (NP, n=53) based on chest imaging. Statistical comparisons of clinical parameters (WBC, lymphocytes, CRP, lipids) utilized Mann-Whitney U and chi-square tests. Variables with P<0.1 were included in logistic binary regression to identify independent risk factors. ROC analysis assessed diagnostic performance. Results: Significant differences were observed in lymphocytes (L), CRP, TG, HDL-C, and LDL-C levels between pneumonia and non-pneumonia groups (P < 0.05). CRP, HDL-C, and LDL-C were identified as independent risk factors for determining whether influenza-MP co-infections were complicated by pneumonia. CRP and LDL-C levels were risk factors associated with pneumonia risk (OR > 1), whereas HDL-C levels showed a strong protective factor association (OR < 1). The ROC curve analysis showed that the combined area under the curve (AUC) for HDL-C + LDL-C (0.878) was significantly higher than the AUCs for CRP + HDL-C (0.809), CRP + LDL-C (0.753), HDL-C (0.807), LDL-C (0.737), and CRP (0.601). The clinical DCA shows that HDL-C + LDL-C has a higher diagnostic value than CRP + HDL-C, CRP + LDL-C, HDL-C, LDL-C, or CRP alone. Conclusion: HDL-C and LDL-C levels independently predict pneumonia progression in influenza-MP co-infected children, with dual-marker assessment enhancing diagnostic accuracy.


Retrospective Evaluation Of Demographic, Clinical, Laboratory Findings And Inflammatory Biomarkers Of Patients Followed With The Diagnosis Of Serum Sickness-Like Reaction, Seda Taşdemir Salar, Alaaddin Yorulmaz, Vildan Güngörer, Şükrü Arslan Dec 2025

Retrospective Evaluation Of Demographic, Clinical, Laboratory Findings And Inflammatory Biomarkers Of Patients Followed With The Diagnosis Of Serum Sickness-Like Reaction, Seda Taşdemir Salar, Alaaddin Yorulmaz, Vildan Güngörer, Şükrü Arslan

Journal of Pediatric Infectious Diseases

Objectives: Serum Sickness-like Reactions (SSLR) are Type 3 hypersensitivity reactions occurring in the presence of certain antigens. Symptoms generally begin 6-21 days after the exposure to antigenic stimulation. In the present study, the purpose was to examine whether there are any changes in these hematological parameters and their prognostic significance in patients diagnosed with SSLR and followed and treated in our clinic. Methods: The files of 122 patients who were hospitalized and followed up with a diagnosis of SSLR in the Pediatric Healthcare and Diseases Clinic between September 2016 and December 2021 were examined retrospectively. Results: A total of 64 …


Application Of The Phoenix Sepsis Score For Diagnosing Sepsis In Children With Measles, Tam Thi Phung, Nguyen The Nguyen Phung, Tuan An Van Ngo, Minh Duy Vo, Hieu Trung Pham, Hai Nhi Thai Pham Dec 2025

Application Of The Phoenix Sepsis Score For Diagnosing Sepsis In Children With Measles, Tam Thi Phung, Nguyen The Nguyen Phung, Tuan An Van Ngo, Minh Duy Vo, Hieu Trung Pham, Hai Nhi Thai Pham

Journal of Pediatric Infectious Diseases

Objective: To assess the prevalence of sepsis and septic shock in children with complicated measles using the Phoenix Sepsis Score Criteria (PSSC) during the first 24 hours of admission to the Infectious Diseases Intensive Care Unit (IDICU). Methods: This prospective observational cohort study was conducted in the IDICU at Children’s Hospital 1, Ho Chi Minh City, Vietnam, from June 2024 to December 2024. The study included 161 children aged 1 month to 16 years with measles-associated complications. Results: A total of 161 cases, with a median age of 9 months (IQR: 6–21), were included. Among them, the 49.7% were infants …