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Lipid Biomarkers Predict Pneumonia Risk In Children With Influenza-Mycoplasma Co-Infections: A Retrospective Cohort Study, Kai-Jing Zhang, Xin-Feng Zhao, Xiao-Juan Lv, Xiao-Hui Huang, Jing Huang, Yan-Yan Zhu

Journal of Pediatric Infectious Diseases

Objective: This study evaluates the prognostic value of high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) levels for pneumonia risk in children co-infected with influenza and Mycoplasma pneumoniae (MP). Methods: We retrospectively analyzed 248 children with influenza-MP co-infection (January 1, 2020–October 30, 2024). Participants were grouped into pneumonia (P, n=195) and non-pneumonia (NP, n=53) based on chest imaging. Statistical comparisons of clinical parameters (WBC, lymphocytes, CRP, lipids) utilized Mann-Whitney U and chi-square tests. Variables with P<0.1 were included in logistic binary regression to identify independent risk factors. ROC analysis assessed diagnostic performance. Results: Significant differences were observed in lymphocytes (L), CRP, TG, HDL-C, and LDL-C levels between pneumonia and non-pneumonia groups (P < 0.05). CRP, HDL-C, and LDL-C were identified as independent risk factors for determining whether influenza-MP co-infections were complicated by pneumonia. CRP and LDL-C levels were risk factors associated with pneumonia risk (OR > 1), whereas HDL-C levels showed a strong protective factor association (OR < 1). The ROC curve analysis showed that the combined area under the curve (AUC) for HDL-C + LDL-C (0.878) was significantly higher than the AUCs for CRP + HDL-C (0.809), CRP + LDL-C (0.753), HDL-C (0.807), LDL-C (0.737), and CRP (0.601). The clinical DCA shows that HDL-C + LDL-C has a higher diagnostic value than CRP + HDL-C, CRP + LDL-C, HDL-C, LDL-C, or CRP alone. Conclusion: HDL-C and LDL-C levels independently predict pneumonia progression in influenza-MP co-infected children, with dual-marker assessment enhancing diagnostic accuracy.

Retrospective Evaluation Of Demographic, Clinical, Laboratory Findings And Inflammatory Biomarkers Of Patients Followed With The Diagnosis Of Serum Sickness-Like Reaction, Seda Taşdemir Salar, Alaaddin Yorulmaz, Vildan Güngörer, Şükrü Arslan

Journal of Pediatric Infectious Diseases

Objectives: Serum Sickness-like Reactions (SSLR) are Type 3 hypersensitivity reactions occurring in the presence of certain antigens. Symptoms generally begin 6-21 days after the exposure to antigenic stimulation. In the present study, the purpose was to examine whether there are any changes in these hematological parameters and their prognostic significance in patients diagnosed with SSLR and followed and treated in our clinic. Methods: The files of 122 patients who were hospitalized and followed up with a diagnosis of SSLR in the Pediatric Healthcare and Diseases Clinic between September 2016 and December 2021 were examined retrospectively. Results: A total of 64 …

Application Of The Phoenix Sepsis Score For Diagnosing Sepsis In Children With Measles, Tam Thi Phung, Nguyen The Nguyen Phung, Tuan An Van Ngo, Minh Duy Vo, Hieu Trung Pham, Hai Nhi Thai Pham

Journal of Pediatric Infectious Diseases

Objective: To assess the prevalence of sepsis and septic shock in children with complicated measles using the Phoenix Sepsis Score Criteria (PSSC) during the first 24 hours of admission to the Infectious Diseases Intensive Care Unit (IDICU). Methods: This prospective observational cohort study was conducted in the IDICU at Children’s Hospital 1, Ho Chi Minh City, Vietnam, from June 2024 to December 2024. The study included 161 children aged 1 month to 16 years with measles-associated complications. Results: A total of 161 cases, with a median age of 9 months (IQR: 6–21), were included. Among them, the 49.7% were infants …

The Role Of Presepsin And Neutrophil Gelatinase-Associated Lipocalin (Ngal) Levels In Pediatric Urinary Tract Infections, Cansu Sert, Ayşe Şahin, Nazan Dalgıç, Zeynep Mine Yalçınkaya Kara

Journal of Pediatric Infectious Diseases

Objective: This study aimed to assess the utility of presepsin and neutrophil gelatinase-associated lipocalin (NGAL) levels, in serum and urine, for diagnosing urinary tract infections (UTIs) and monitoring response to treatment. By evaluating the specificity of these biomarkers for UTIs, this study sought to contribute to the existing literature. Methods: A single-center prospective study was conducted, with 32 pediatric patients diagnosed with UTIs and 32 healthy pediatric controls. Blood and urine samples were taken at the time of hospitalization and at the 72nd hour of treatment for the UTI group, and during routine clinic visits for the control group. Serum …

Virtual Teaching During Covid-19: Attitudes, Abilities, And Educational Needs Of Cooperative Extension Staff, Kathryn Yerxa, Kayla L. Parsons, Jennifer Lobley

Journal on Empowering Teaching Excellence

Access the online Pressbooks version of this introduction here.

This study aimed to 1) identify the attitudes and abilities of Cooperative Extension staff regarding the delivery of virtual educational programming based on their characteristics and 2) identify professional development priorities to effectively deliver programming virtually. We disseminated an adapted Faculty Readiness to Teach Online questionnaire to Cooperative Extension staff via Qualtrics. Mean and standard deviation were calculated from complete surveys (n = 67) for each virtual programming competency in the self-reported attitude and ability sections, categorized by position type, years of teaching, and program area. We conducted a MANCOVA to …

Coaching Undergraduates, A Conceptual And Practical Guide, Anna Carissa Rozzo

Journal on Empowering Teaching Excellence

Access the online Pressbooks version of this introduction here.

The overall aim of this paper is to provide a holistic orientation to the practice of person-centered coaching while providing tangible methods that faculty and advisors in higher education may be able to integrate into their professional practices. This conceptual paper explores the theoretical and practical intersections of coaching and teaching, presenting a flexible modality to support student-centered learning. The author provides readers with general guidance and templates for goal setting, problem solving, and assessment that practitioners may adapt to their own contexts.

Coaching Graduate Students Through Early Childhood Focused Community-Engaged Learning: Graduate Student Perspectives And Course Design, Sarah Tulane, Shirlene Call Law

Journal on Empowering Teaching Excellence

Access the online Pressbooks version of this introduction here.

Community-engaged learning (CEL) in graduate-level coursework contributes to professional development and growth. CEL course design requires intentional and time-intensive planning. A graduate-level child development course was designed for CEL using the following process: needs assessment, training for community education, preparing materials, practicing with feedback, presenting to an authentic audience, and reflection on the experience. Students created presentations for authentic parent audiences based on a needs assessment of parent interest in child development topics. Reflections from four students in the course were analyzed using a general thematic analysis technique. Three themes emerged. …

Full Issue: Journal On Empowering Teaching Excellence, Volume 9, Issue 2, Fall 2025

Journal on Empowering Teaching Excellence

The full-length Fall 2025 issue (Volume 9, Issue 2) of the Journal on Empowering Teaching Excellence

Access the online Pressbooks version (with downloadable EPUB format) here.

This issue of the Journal on Empowering Teaching Excellence brings together articles that highlight approaches for engaging students and broader communities through teaching, coaching, and assessment in higher education. The contributions examine community-engaged learning in graduate coursework, the use of coaching practices to support student-centered teaching and advising, Cooperative Extension staff readiness for virtual instruction, and alternative assessment strategies aimed at increasing engagement and reducing anxiety in challenging STEM courses. Collectively, the articles …

The Influence Of Early Detection And Intervention Providers' Actions And Communication On Parental Emotions And Early Intervention Engagement After A Child Is Diagnosed With Hearing Loss: A Scoping Review, Charlene M. Watson, D. Ellen Rick, Jillian Ingratta, Patti-Jo Sullivan, Xurong Zhao, Sheila Moodie

Journal of Early Hearing Detection and Intervention

Despite well-intentioned early hearing detection and intervention (EHDI) programs, parents receiving a newborn hearing loss diagnosis often experience distress, uncertainty, and fear, which can impact their readiness to engage in early intervention. The communication and support provided by clinicians in early hearing detection and intervention play a critical role in helping families navigate emotions, overcome barriers, and actively participate in EHDI programs. The purpose of this scoping review is to advance our knowledge of the following: For parents who have a newborn newly diagnosed with hearing loss, how do the actions/behaviors and communication (or lack thereof) of EHDI providers influence …

Geographic And Sociodemographic Disparities In Early Hearing Detection And Intervention Adherence, Amanda Pavan, Anton Kvit, Michael Van Skiba, Analise Ristic, Kirsten R. Coverstone

Journal of Early Hearing Detection and Intervention

Early identification and intervention are crucial to minimizing impacts of congenital hearing loss. Early Hearing Detection and Intervention (EHDI) programs recommend newborn hearing screening before one month of age and a diagnostic audiologic evaluation before three months for infants who do not pass the screening. However, not all infants meet these benchmarks, as geographic and sociodemographic factors may influence adherence.

Addresses of primary contacts and audiology clinics were geocoded to calculate drive times to the nearest clinic in 10-minute intervals for infants born in Minnesota between 2019 and 2021. Birth location, NICU admittance, and sociodemographic characteristics were also analyzed. Random …

Readability Of Spanish Language Early Intervention Materials For Children Who Are D/Deaf And Hard Of Hearing, Torri Ann Woodruff-Gautherin

Journal of Early Hearing Detection and Intervention

This paper discusses how accessibility to information may be limited for families and considers why this is of a critical concern for families using Spanish. To look at accessibility of materials online, six search terms were used in the Google search engine. Ninety-one unique websites were included for readability analysis (43 written in English and 48 written in Spanish). Readability was assessed for English materials using Flesh-Kincaid Grade Level (FKGL; mean=12.83, sd=2.737) and Flesh-Kincaid Ease of Reading Score (FKERS; mean=35.602, sd=15.651). FKGL scores were consistent with prior work (Woodruff & Cienkowski, 2021). For materials written in Spanish readability was assessed …

Fine And Gross Motor Skills Assessment, From A Caregiver's Perspective, In Children With Hearing Loss Using A Modified Ages And Stages Questionnaire (Asq-3), Steven M. Doettl, Patrick N. Plyler, Erin Plyler, Kelly R. Yeager, Leeann Hutker, Ginger Tallmadge, Aspen Gutknecht, Amy Becker

Journal of Early Hearing Detection and Intervention

Purpose: The purpose of this study was to determine if there is a significant difference on ASQ-3 (Ages and Stages Questionnaire version 3) Gross (ASQ G) and Fine (ASQ F) Motor scores between children with sensorineural hearing loss (SNHL) and children with normal hearing.

Methods: Data was gathered from the ASQ-3 as reported by parents/caregivers of 61 children (28 normal hearing children and 33 children with SNHL) ages 6-36 months. Results were averaged across the participants for both groups. Independent sample t-Tests were used to assess for any statistically significant difference in the ASQ scores between groups. Chi-square analysis …

From Policy To Practice In Deaf Education: American Sign Language And Spoken English Outcomes Of Deaf And Hard Of Hearing Children In Kansas, Jena Mcdaniel, Shreyas Teegala, Rebecca Maloney, Angie Walker, Mary S. Dietrich, Matthew L. Hall, Leah C. Geer, Julie Bustos

Journal of Early Hearing Detection and Intervention

Purpose: In the context of the recent expectation for state Early Hearing Detection and Intervention programs to track language milestones of deaf and hard of hearing (DHH) children, we examine how to leverage statewide assessment programs for improving language outcomes of DHH children. We present the degree to which DHH children in Kansas are meeting their language milestones for American Sign Language (ASL) and English and the influence of two measurement features.

Method: Performance on the ASL/English Language Milestones for 198 children who were DHH (aged 1 to 8) was analyzed for attainment of age-expected language skills and …

Factors Affecting Timely Intervention For Children Who Are Deaf Or Hard Of Hearing: Perceptions Of Texas Early Intervention Providers, Julianna C. Wanek, Sandy K. Bowen

Journal of Early Hearing Detection and Intervention

The purpose of this study was to investigate the perceptions and experiences of early childhood intervention (ECI) professionals concerning timely intervention for children who are deaf or hard of hearing (DHH) in Texas. The data for this study was collected through semi-structured, qualitative interviews of 10 ECI practitioners in Texas. Interview data analysis followed the six-phase framework of Thematic Analysis. The data collected identified three major themes: (a) roles and responsibilities, (b) family attributes and experiences, and (c) “deaf” is different. Overall, the findings reveal that the referral and service process for infants and toddlers who are DHH in Texas …

Journal Of Early Hearing Detection And Intervention: Volume 10 Issue 2, Pages 1-80

Journal of Early Hearing Detection and Intervention

No abstract provided.

Dementia In Downs Syndrome – A Case Report, Clarita Shynal Martis Ms, Elsa Sanatombi Devi Dr, Panambur Venkataraya Bhandary Dr

Manipal Journal of Nursing and Health Sciences

Down syndrome, is a chromosome 21-related genetic condition, frequently manifests as intellectual difficulty, growth retardation, and distinctive facial traits. People with Down’s Syndrome usually develop Dementia, a major cause of cognitive impairment, impaired judgment memory loss in their midlife. The present report describes a case study of a female diagnosed with dementia in Down’s Syndrome. The report explores the challenges her parents faced in securing appropriate care when diagnosed with dementia and Down's syndrome. It aims to inform caregivers about the best practices for home care in such cases. It follows the woman's history from birth until her dementia was …

Influence Of Postpartum Depression Among Mothers On Cognitive Development In Children: A Scoping Review, Navyashree Gc, Aabha Jain, Malika Mudit, Manavi Manoj Kumar, Rachna Shetty, Riya Prabhu, Salma Zameer

Manipal Journal of Nursing and Health Sciences

The interplay of maternal care, communication, and emotional expression of parent-child interactions dramatically influences the cognitive and emotional growth of the child during their formative years. Postpartum depression poses a significant public health concern, impacting mothers' caregiving abilities and infants' sensitive early development. The present scoping review aims to explore the literature that delves into the influence of postpartum depression among mothers on the child’s cognitive development. For this scoping review, a systematic search was conducted for studies in the PubMed and Scopus databases. Studies published in the English language from 1990 to 2023 focusing on mothers with postpartum depression …

Rheumatic Diseases In Pregnancy: Emerging Pharmacologic Management And Safety, Amanda Rawa, Katherine Ghattas

Transformative Medicine

Rheumatic diseases distinctly affect women of childbearing age, creating complex challenges in balancing maternal disease control with fetal safety during pregnancy and lactation. This review summarizes the pathophysiology and management of common rheumatic diseases, with a focus on the safety and efficacy of conventional and biologic disease-modifying antirheumatic drugs (DMARDs). Particular emphasis is placed on pregnancy-compatible therapies, contraindicated agents, and emerging evidence supporting the use of select biologics such as tumor necrosis factor inhibitors (TNKs). Current guidelines and primary literature have been reviewed to show the importance of preconception counseling and individualized treatment plans to optimize maternal and fetal outcomes.

Electrocardiographic Clues To Arrhythmogenic Right Ventricular Cardiomyopathy, Devi Parvathy Jyothi Ramachandran Nair, Muhammad Asad Hanif

Transformative Medicine

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by fibrofatty replacement of the right ventricular (RV) myocardium, predisposing to ventricular arrhythmias, RV dysfunction, and sudden cardiac death. Early recognition relies heavily on electrocardiographic (ECG) findings, which often precede overt structural changes. We report a case of a 28-year-old woman presenting with intermittent chest pressure, palpitations, and mild exertional dyspnea. Vital signs were stable, and troponin was normal. Initial 12-lead ECG demonstrated normal sinus rhythm with frequent premature ventricular contractions (PVCs) and T-wave inversions in leads V1–V3. Continuous telemetry revealed frequent runs of monomorphic non-sustained ventricular tachycardia (NSVT) with …

The Aftermath Of Overturning Roe V. Wade: A Review Of Legal, Social, And Health Implications, Eden Parks M.D.

Transformative Medicine

Roe versus Wade occurred in 1973 and was a landmark case in the United States. It guaranteed the right to abortion until 2022, when the Dobbs versus Jackson case was decided and the U.S. Supreme Court overturned Roe. This abolished the right to abortion and left it up to the states. The Dobbs decision has reshaped the framework for reproductive rights in the United States. This paper focuses on the multifaceted outcomes of the Dobbs decision, highlighting the legal, social and health implications. Through a study of recent research, legal analyses, and public health reports, this article assesses the …

The Implementation Of Indoor Urban Gardening: A Microgreens Pilot Study In A University Setting, Kathryn Chang, Samantha Brink, Annette Gadegbeku

Transformative Medicine

Introduction: “Food deserts” are geographical areas that lack affordable full-service grocery stores and have higher densities of unhealthy or “fast food” options. These deserts not only exist in communities such as Philadelphia, but also on college campuses. One solution to creating access to fresh vegetables is urban farming, which refers to green areas (i.e. community gardens) that provide places for food to be grown by local residents. Microgreens Health Outreach Project (HOP), aimed to build and implement a small, indoor community garden cart within the Health Sciences Building (HSB) at Drexel University; the organization hoped that this cart would be …

Impact Of Early Term Induction Of Labor On Cesarean Delivery And Maternal-Fetal Outcomes In Patients With Obesity: A Retrospective Cohort Study, Nathanael N. Hoskins, Priya Patel, Thomas Wasser, Xuezhi Jiang

Transformative Medicine

Introduction: Obesity (body mass index [BMI] ≥ 30 kg/m²) is increasingly prevalent in pregnancy and is associated with numerous complications, including gestational diabetes, hypertension, and higher cesarean delivery (CD) rate. There are many risks for patients with obesity during pregnancy; however, there is little evidence supporting early-term (37 0/7 to 38 6/7 weeks of gestation) induction of labor (IOL) to reduce complications. This study aimed to evaluate whether IOL in patients with obesity is associated with a decreased CD rate.

Methods: This retrospective cohort study included pregnancies that underwent IOL between 37 0/7 and 41 6/7 weeks of gestation from …

Opportunity For Increasing Applicant Diversity In Gynecologic Oncology Fellowships, Priyanka Raju Md, Tamara Lalovic Do, Alexandar Lalovic

Transformative Medicine

Introduction: The term healthcare disparity describes differences in access to medical care between population groups. Minimizing the care gap and improving access to care for historically minoritized populations will require a multifaceted approach. Increasing diversity in the healthcare workforce has the potential to lead to significant improvements aimed at minimizing inequity. Fellowship training programs in Gynecologic Oncology serve as the gatekeeper for the workforce of Gynecologic Oncologists. Efforts at improving diversity at the fellowship level are necessary to increase the diversity of practicing physicians. The objective of this study is to assess Gynecologic Oncology fellowship websites for information emphasizing a …

Development Of An Evidence-Based Educational Intervention To Increase Correctional Nurses’ Knowledge Of Mental Health Crisis Management, Jacqueline Parrish

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) educational intervention targeted correctional nurses and aimed to enhance their knowledge of mental health crisis management. Correctional environments often lack training for managing mental health emergencies, which can negatively impact safety. The goal was to increase correctional nurse knowledge of mental health emergency management. The guiding question was whether an educational intervention would increase correctional nurses’ knowledge of mental health crisis management by a minimum of 20% following a structured, evidence-based educational session. A pretest and posttest design was used in the project. A total of 20 participants completed a pretest, posttest and program …

Lived Oral Health Experiences Of Syrian Refugees In The United States, Taniya Michael Henry-Sangar

Walden Dissertations and Doctoral Studies

The oral health status of Syrian refugees has been impacted by war and displacement since the 2011 civil war. To date, limited in-depth knowledge is available on oral health experiences of resettled Syrian refugees in the United States. The purpose of this qualitative study was to explore lived oral health experiences of resettled Syrian refugees before, during, and after the 2011 Syrian civil war. The health belief model (HBM) and theory of planned behavior (TPB) were theoretical frameworks for this phenomenological inquiry. The study was guided by semi-structured phone interviews with a purposeful sample of 11 Syrian refugees over the …

Adapter Changes Of Central Line Patients On Total Parenteral Nutrition, Courtney Erin Schappell

Walden Dissertations and Doctoral Studies

Central line-associated bloodstream infections (CLABSIs) remain a significant and preventable patient safety issue, especially among hospitalized patients receiving total parenteral nutrition (TPN). Patients on TPN face a higher risk of infection due to the high glucose content of the solution and the frequent access required for central line therapy. The Centers for Disease Control and Prevention and the Agency for Healthcare Research and Quality have recognized CLABSI prevention as a national priority. In addition, there is emphasis on high-risk groups like patients receiving TPN. The Infusion Therapy Standards of Practice, an evidence-based guideline, recommends catheter care, including timely adapter (i.e., …

A Phase-Ii Randomized Controlled Pilot And Feasibility Study Of Nicotinamide Riboside Supplementation In Older Adults With Amnestic Mild Cognitive Impairment, Christopher R. Martens, Kevin P. Decker, Theodore M. Deconne, Faria Sanjana, Fiona Horvat, Nicholas A. Rizzi, Catherine Awad, Elizabeth Habash, Joshua C. Hobson, Michael L. Armstrong, Nichole Reisdorph, Ryan T. Pohlig, Alyssa M. Lanzi, Curtis L. Johnson, Matthew L. Cohen, James M. Ellison

Department of Psychiatry and Human Behavior Faculty Papers

Abstract

Background

The decline of nicotinamide adenine dinucleotide (NAD+) with aging may elevate risk of Alzheimer’s disease and related neurocognitive disorders (ADRD) by impairing cellular energy metabolism and reducing cerebral blood flow.

Method

We conducted a 12-week double-blind, randomized, placebo-controlled pilot study to evaluate the safety, tolerability, and preliminary efficacy of the NAD+ precursor, nicotinamide riboside (NR; 500 mg b.i.d.), for enhancing cognitive function and cerebral perfusion in older adults with mild cognitive impairment (MCI).

Result

52 participants (33 females, 19 males) were randomized and 42 completed the trial (NR = 22, placebo = 20). Adherence was similar between groups …

Nurse Practitioner-Led Mobile Clinics: A Lifeline For Underserved Communities, Michelle Hepburn

DNP Qualifying Manuscripts

Traditional brick-and-mortar clinics have failed underserved populations, especially those who are unhoused, living with serious mental illness or experiencing substance use disorders. Nurse practitioner (NP)-led mobile health clinics (MHC) offer an exceptional opportunity to impact healthcare for underserved populations. This model addresses the constructs of social determinants of health replacing episodic care with longitudinal outreach. It offers an equitable and scalable model that is transformative; reducing disparities, and promoting sustainable health outcomes for underserved populations, and it creates a pathway that reduces avoidable emergency department visits and advances health equity.

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.

The Nonlinguistic Factors That Predict Spanish Oral Proficiency, Merrie Kay Ames

Theses and Dissertations

This study investigates the predictive power of self-assessment and nonlinguistic factors in determining Spanish oral proficiency among university learners. Drawing on data from 2,475 undergraduate students enrolled in a third-year Spanish course at Brigham Young University, the research examines how self-assessed speaking ability and experiential background variables--including age of acquisition, mission service, dual immersion, and study abroad--influence Oral Proficiency Interview - Computer (OPIc) scores. A one-way ANOVA revealed a statistically significant but modest relationship between students' calibration (self-assessment minus actual ability) and their OPIc ratings, suggesting that learners can generally approximate their speaking proficiency within two sublevels. A multiple regression …