Digital Commons Network^™

Longitudinal Association Between Sleep Disturbance And Disordered Eating In Adolescents: The Mediating Role Of Emotion Dysregulation, Antonia Louise Hamilton

Theses - ALL

Accruing evidence suggests a significant relationship between sleep disturbances and disordered eating. Early adolescence is a period of heightened vulnerability for sleep disturbances and disordered eating. However, the longitudinal relationship between sleep disturbance and disordered eating remains unclear in early adolescent samples. The current study aims to examine if sleep disturbance longitudinally predicts disordered eating in early adolescents three years later, how the odds of having clinically significant disordered eating change per each unit increase in sleep disturbance, and if emotion dysregulation mediates these relationships. It is hypothesized that baseline sleep disturbance will predict greater disordered eating at follow-up, and …

Exploring The Role Of Astrocyte System Xc– In Excitatory/Inhibitory Balance, Samantha Olivia Sutton

Theses - ALL

Astrocytes play a central role in maintaining excitatory/inhibitory (E/I) balance in the central nervous system by supporting intracellular glutathione (GSH) synthesis and regulating extracellular glutamate. System xc– (Sxc–), an obligate cystine/glutamate antiporter encoded by SLC7a11, couples the import of L-cystine with the export of L-glutamate. It is highly expressed throughout the cortex, hippocampus, striatum, and cerebellum, where its activity provides cystine—the rate-limiting substrate for cysteine-dependent GSH production—and contributes to ambient glutamatergic tone. Although global loss of Sxc– alters seizure threshold and redox homeostasis, whether these effects arise specifically from the loss of astrocytic Sxc– has remained unresolved. This thesis examined …

Investigating The "Tend-And-Befriend" Stress Response As A Risk Factor For Sexual Victimization Among College Women, Emily Kathleen Presutti

Theses - ALL

Sexual victimization of college women is a significant public health concern on U.S. college campuses. Traditional research on the human stress response has focused on the "fight-or-flight" model, which may not adequately capture female-typical responses in stress-inducing situations. Using a mixed-methods design, we sought to determine whether the "tend-and-befriend" stress response serves as a potential correlate of sexual victimization among college women and examine whether it contributes additional variance beyond established correlates of sexual victimization such as alcohol use, history of sexual victimization, and involvement in campus party culture. The study was conducted in two phases. In Phase I, 128 …

Clinical Outcomes Of Electrosurgery For Management Of Giant Condyloma Acuminata: A Systematic Review, Fortunia Mona Eviani, Maureen Miracle Stella, Arief Budiyanto, Satiti Retno Pudjiati, Alessandro Alfieri

Folia Medica Indonesiana

Giant condyloma acuminata (GCA) is a rare sexually transmitted disease that is locally aggressive with a high recurrence rate. Electrosurgery is a minimally invasive procedure that may be less expensive, quicker, and safer than conventional surgery. This study aimed to review the management of GCA with electrosurgery. We followed PRISMA 2020 guidelines to search and retrieve literature in the following databases: PubMed, ProQuest, Taylor & Francis, ScienceDirect, JSTOR, and SAGE without time restrictions. The study inclusion criteria were original articles that studied the outcome of electrosurgery in GCA. The authors evaluated the risk of bias using the Joanna Briggs Institute …

Comparing The Antibacterial Efficiency Of Chitosan And Dextran As Nanocomposites Against Escherichia Coli, Saja Sachit, Alaa Al-Taie

Baghdad Science Journal

Nanoparticles (NPs) are widely used in many different fields and applications. In this study, Silver (Ag) NPs and Titanium dioxide (TiO₂) NPs were generated using the laser ablation method by using Q-switched Nd: YAG laser. In addition, Chitosan (CS) and Dextran nanopolymers were chosen to prepare the nanocomposites by combining the two types of nanopolymers with the generated NPs in different ratios to obtain the samples: CS and Dextran as a control, CS-Ag, CS-TiO₂, CS Ag-TiO₂, Dextran-Ag, Dextran-TiO₂, and Dextran Ag-TiO₂. Several tests were carried out on these nanocomposites such …

Biosynthesis Of Silver Nanoparticles From Halophilic Green Algae (Dunaliella Viridis) Extract And It Is Antibacterial Activity, Payman Omer Salih, Trifa Kamal Jalal, Hoshyar Abdullah Azeez

Baghdad Science Journal

Biological synthesis of nanoparticles is a new area of nanotechnology that has advantages in terms of cost and the environment compared to chemical or physical synthesis methods. The current work is carried out to synthesize silver nanoparticles (AgNPs) utilizing green algae (Dunaliella viridis Teodoresco 1905) extract as a reducing and capping agent and to evaluate the antibacterial efficacy of AgNPs. The. The measures of UV-V spectroscopy, XRD, TEM, SEM-EDSand FTIR were used to characterize the synthesized silver nanoparticles. Additionally, agar well diffusion and minimum inhibitory concentration (MIC) methods were used for antibacterial activity. The plasmon absorbance of AgNPs was …

State Of California Cannabis Reporting, University Of Mississippi – National Center For Cannabis Research And Education

California

No abstract provided.

Hepatocyte-Specific Lrp1 Silencing Exacerbates Brain Amyloidosis Without Compensatory Ldl Receptor Family Involvement, Brian Carson, Josephine Chu, Devaraj V. Chandrashekar, Jerome Garcia, Rachita K. Sumbria, Derick Han

Pharmacy Faculty Articles and Research

Background

LDL receptor related protein 1 (LRP1) is a major hepatic receptor involved in lipoprotein metabolism, protease degradation, transmembrane receptor modulation, and clearance of excess protein, such as Aβ. Decreased expression of LRP1 due to liver injury can impair receptor-mediated clearance, increasing Aβ availability in the periphery. We investigated the effects of hepato-specific silencing of LRP1 on Aβ deposition in the brain. Additionally, other LDL family members (LRP5, LRP6, and LDLR) that may participate in Aβ clearance were monitored in the liver to ensure non-compensatory effects of LRP1 silencing.

Method

4-month-old male double transgenic (APP/PS1) AD mice were injected with …

Too Much Of A Good Thing: Otc Calcium Carbonate Overdose Causing Milk-Alkali Syndrome In A Psychiatric Patient., Alexandra She, Sangay Bhutia, Francis Jenney

PCOM Scholarly Works

BACKGROUND: In the United States, milk-alkali syndrome or calcium-alkali syndrome is the third most common cause of hypercalcemia, after primary hyperparathyroidism and malignancy. Clinically, patients present with a triad of hypercalcemia, acute kidney injury, and metabolic alkalosis. Classically, it has been associated with excessive intake of calcium and absorbable alkali, and recently it has become more common in postmenopausal females who ingest calcium supplements for osteoporosis.

CASE PRESENTATION: Here, we present the case of a 72-year-old Caucasian female with a longstanding diagnosis of bipolar I disorder who presented to the Emergency Department (ED) with a sudden onset of generalized weakness, …

Policies Of Pain: Neoliberal Rhetorics Of The Opioid Epidemic In Culture And Policy, Gina Arlene Stinnett

Dissertations - ALL

This dissertation outlines and examines the Neoliberal rhetorics of choice and responsibility, and how these rhetorics are utilized in policy and culture related to the Opioid Epidemic in the United States. Through this examination of neoliberal rhetorics in policy and culture, I unpack the circular influence these two have on each other—i.e., cultural assumptions inform policy decisions, and established policy can slowly influence cultural assumptions. The key area in which these two influence each other is through rhetoric, therefore I argue that in addition to an economic and cultural structure, neoliberalism is a rhetorical structure—it shapes our society specifically through …

Construction And Application Of Knowledge Graph For Quality Management In Bridge Pile Engineering, Fang Xiaofeng, Dong Runhao, Gu Yanke, Pan Yanran

Journal of China & Foreign Highway

To enhance the efficiency of quality management in bridge pile foundation construction,this study constructed a knowledge graph applicable to the construction field of bridge pile foundation engineering to enable systematic representation and intelligent organization of knowledge.A methodology combining top-down design and bottom-up design was adopted to develop a framework for constructing a knowledge graph for the quality management of bridge pile foundation construction that encompasses both the schema layer and the data layer.The schema layer was established through ontology modeling,clarifying the concept categories,hierarchical structure,and their attribute relationships.The data layer employed a bidirectional long short-term memory (BiLSTM ) network integrated with …

Development And Evaluation Of The Agitation In Alzheimer's Screener For Caregivers (Aasc): A Clinical Tool To Screen For Agitation., Carolyn Clevenger, W Clay Jackson, Jared Stroud, Malaak Brubaker, Mehul Patel, Iwona Bucior, Emily Bratlee-Whitaker, T Michelle Brown, Sheri Fehnel, Sue Peschin, Jeffrey Cummings, George Grossberg

Ambulatory and Primary Care Articles

OBJECTIVE: Although agitation is a common neuropsychiatric symptom in Alzheimer's dementia, it can be challenging to recognize and diagnose. Caregivers of individuals with Alzheimer's dementia are often the first to encounter agitation behaviors but may struggle to recognize and communicate symptoms to healthcare professionals (HCPs). Here, we describe the development and evaluation of the Agitation in Alzheimer's Screener for Caregivers (AASC), a practical screening tool to identify agitation symptoms and facilitate caregiver-HCP communication.

METHODS: The AASC was developed based on the International Psychogeriatric Association (IPA) criteria for agitation in cognitive disorders, input from multidisciplinary experts, and qualitative interviews with caregivers …

Surgical Treatment Of Post-Traumatic Elbow Stiffness In Pediatric Patients: A Systematic Review And Meta-Analysis, Roya Khorram, Areeb Ahmad, Reza Vafadar, Ronald Joseph Shamus, Surena Namdari, G. Russell Huffman, Amir R. Kachooei

Rothman Institute Papers

BACKGROUND: Post-traumatic elbow stiffness (PTES) has been reported in up to 21% of pediatric patients following elbow fractures and can profoundly compromise a child's function, and independence. The primary surgical approaches include open and arthroscopic arthrolysis, both of which have demonstrated improvements in range of motion (ROM) and functional scores. This systematic review and meta-analysis aims to compare the effectiveness, ROM, and complication rates between open and arthroscopic release in pediatric patients with PTES.

METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were utilized to conduct a systematic review and meta-analysis on surgical treatment for PTES. Comprehensive …

Espacios De Cambio: Evaluating Community-Based Art Therapy Within The Latinx Community, Bennie Guzman

Theses - ALL

This research presented in this graduate thesis explores the social-emotional benefits of community-based approaches of art therapy within the Latinx community. The literature contextualizes the socio-historical experiences of the Latinx community and presents an argument for the use of a community-based approach of art therapy. This study evaluates the social-emotional benefits of the “Arts as Mindfulness” program, an initiative created by the author in collaboration with La Casita Cultural Center at Syracuse University. Methods of data collection include creative reflections and a focus group with program participants. The research conducted data analysis using a hermeneutic phenomenological approach. Themes that arose …

Assessing The Gender Differences In Mental Health Access And The Intersectionality Of Depression, Anxiety, Stress Between Black Men And Black Women During Covid-19, Turquoise Ef'e Pipes

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic, which emerged in the past five years, has had a particularly severe impact on well-being, mental health, and access to care for Black communities. Therefore, the purpose of this quantitative study, grounded in intersectionality theory was to assess gender differences between Black women and Black men confronted with depression, anxiety, stress symptoms and mental health access during the crisis of COVID-19, which has been under researched within this demographic. The study sample included participants from various cities across the United States who lived through the COVID-19 pandemic from March 2020 to March 2023 (n= 104). A MANOVA …

Virtually Present In The Vastness: Vr’S Pathway To Awe And Appreciation, David Paul Peters

Dissertations - ALL

This dissertation explores how spatial presence in Virtual Reality (VR) creates awe and appreciation through the role of perceived vastness. 92 participants played a custom-built VR game (VR Nature Photographer) in three environments designed to be low, medium, and high in vastness. A repeated-measures design measured spatial presence, vastness, awe, and appreciation across conditions. Results showed higher vastness increased all four outcomes, with awe and vastness having the largest effect sizes and presence and appreciation medium sized. Mediation analyses showed perceived vastness fully mediated the effect of spatial presence on awe in all vastness conditions and partially mediated its effect …

Building Bridges: Industrial Trade Unions In A Changing Climate, Nicole Möller

Dissertations - ALL

This dissertation examines how German industrial trade unions and workers in the automobile and coal industries navigate the profound challenges of the green transition. Workers’ experiences are situated within a broader political-economic context shaped partly by market-led decarbonization efforts, welfare retrenchment/austerity, erosion of progressive institutions in society, and global competition, as well as a global restructuring of value accumulation. The analysis critically engages with unions’ current responses to a market-led transition and their implications for labor’s future. The dissertation develops its argument across three empirical chapters. Chapter 2 investigates workplace-level changes in coal mining and automobile production, analyzing how workers …

Balancing Robustness And Practicality In Model Compression, Personalization, And Healthcare Interventions, Sawinder Kaur

Dissertations - ALL

Advances in machine learning have enabled significant progress in generating robust solutions. However, designing solutions that balance robustness while meeting the practical constraints of diverse applications, such as limited resources and data, remains a challenge. We explored three key aspects of this interplay: verified robust compressed neural networks, context-wise robust personalization, and reliable counterfactual interventions for healthcare. First, we introduce VeriCompress, a novel framework to streamline the synthesis of compressed neural networks with formal guarantees of adversarial robustness. This enables the deployment of reliable and efficient models in resource-constrained environments, such as smartphones. Second, we developed CRoP (Context-wise Robust Static …

On Detecting Change-Points Of A Segmented Logistic Regression Model, Jingwen Li

Dissertations - ALL

This dissertation investigates the problem of change-point detection in segmented logistic regression models, where the total number of change-points is unknown. We consider both unconstrained models, which allow discontinuities at change-points, and constrained models, which impose continuity across change-points. The central challenge is to determine the number of change-points and to accurately estimate their locations, while ensuring valid statistical inference for the associated regression coefficients. We begin by introducing a set of regularity assumptions that underlie the theoretical analysis throughout this work. For a given number of change-points, we present algorithms to estimate their locations and obtain the maximum likelihood …

Three Essays On The Supplemental Nutrition Assistance Program (Snap): Examining External Shocks, Protective Effects, And Administrative Challenges, Hyojeong Kim

Dissertations - ALL

Abstract In this dissertation, I present three studies that examine how different forms of inconsistency—arising from timing disruptions, eligibility structures, and administrative churn—shape the functioning and effectiveness of the Supplemental Nutrition Assistance Program (SNAP). Although SNAP is designed to provide a reliable source of food assistance, access to benefits is not always predictable, continuous, or evenly accessible. The studies show that inconsistencies can emerge through external shocks that alter the timing of benefit delivery, through eligibility rules tied to disability determinations in other programs that may exclude self-reported disabled households from accommodations, and through administrative procedures that generate temporary interruptions …

Mapping Research Trends On Mental Health Literacy Among University Students: A Bibliometric Systematic Review, Eko Pramudya Laksana, Muslihati Muslihati, Arbin Janu Setiyowati, Salsabila Kholifahtun Nisa, Muhammad Nur Hudha, Margaret Kehinde Soetan

Jurnal Kajian Bimbingan dan Konseling

Mental health is a global issue that has received increasing attention, particularly among university students. Mental health literacy (MHL) is an important factor in promoting students' psychological well-being through knowledge, attitudes, and the ability to recognize and address mental health problems. This study aims to map the developmental trends of MHL research among university students in order to provide a comprehensive overview of the direction and focus of studies in this field. This research employed a bibliometric literature review approach by analyzing 48 journal articles indexed in the Scopus database and published between 2021 and 2025. The findings indicate that …

Bridge Damage Detection And Bim Localization Methods Based On Image Recognition, Li Yu, Guo Hongjun

Journal of China & Foreign Highway

To overcome insufficient information of 2D detection data in traditional bridge maintenance,which hinders precise decision-making,this study proposed an automated method based on deep learning and structure from motion (SfM ) technology,which realized the complete process from image recognition to the accurate mapping of damage information in a building information model (BIM ).First,the YOLOv 8 deep learning model was used to automatically detect bridge surface damage.Second,the SfM technology was applied for the local 3D reconstruction of the damage area and to determine the 3D coordinates of the damage.Then,the least squares method was used to align the local coordinate system with the …

Stimulant Medications Affect Arousal And Reward, Not Attention Networks, Benjamin P Kay, Muriah D Wheelock, Ryan V Raut, Roselyne J Chauvin, Athanasia Metoki, Aishwarya Rajesh, Andrew Eck, Jim Pollaro, Anxu Wang, Vahdeta Suljic, Babatunde Adeyemo, Noah J Baden, Kristen M Scheidter, Julia S Monk, Forrest I Whiting, Nadeshka Ramirez-Perez, Samuel R Krimmel, Anita Randolph, Jarod L Roland, Ginger E Nicol, Timothy O Laumann, Scott Marek, Evan M Gordon, Marcus E Raichle, Deanna M Barch, Nico U F Dosenbach, Et Al.

2020-Current year OA Pubs

Prescription stimulants (e.g., methylphenidate) are thought to improve attention, but evidence from prior fMRI studies is conflicted. We utilized resting-state fMRI data from the Adolescent Brain Cognitive Development Study (n = 11,875; 8-11 years old) and validated the functional connectivity findings in a precision imaging drug trial with highly sampled (n = 5, 165-210 min each) healthy adults (methylphenidate 40 mg). Stimulant-related connectivity differences in sensorimotor regions matched fMRI patterns of daytime arousal, sleeping longer at night, and norepinephrine transporter expression. Taking stimulants reversed the effects of sleep deprivation on connectivity and school grades. Connectivity was also changed in salience …

Phospholipid Scramblase 1 (Plscr1) Regulates Interferon-Lambda Receptor 1 (Ifn-Λr1) And Ifn-Λ Signaling In Influenza A Virus (Iav) Infection, Alina Xiaoyu Yang, Lisa Ramos-Rodriguez, Parand Sorkhdini, Dongqin Yang, Carmelissa Norbrun, Sonoor Majid, Sanghyun Lee, Yong Zhang, Michael Holtzman, David F Boyd, Yang Zhou

2020-Current year OA Pubs

Phospholipid scramblase 1 (PLSCR1) is an interferon-stimulated gene (ISG) that has several known anti-influenza functions. However, the mechanisms in relation to its expression compartment and enzymatic activity have not been completely explored. Moreover, only limited animal models have been studied to delineate its role at the tissue level in influenza infections. Our results showed that influenza A virus (IAV)-infected

Perceptions Of Lumbee Tribe Members On Participating In Diabetes Type Ii Prevention Practices, Jeremy Wesley Lowery

Walden Dissertations and Doctoral Studies

Type II diabetes (DB2) is one of the leading causes of death in the United States, whether directly or as a comorbidity. This is especially alarming for Native Americans, who have the highest DB2 prevalence and death rates when compared to their non-Native American peers. This qualitative phenomenological study explored the lived experiences of Lumbee Tribe members in Robeson County regarding DB2. The health belief model was used as a lens through which to understand and interpret findings. In-person semi-structured audio-recorded interviews were conducted with 12 participants recruited through social media. Data were coded and analyzed using deductive thematic analysis. …

Antifungal Activity Of Nutmeg Mace (Myristica Fragrans Houtt) Ethanol Extract Against Candida Spp., Muhammad Akbar Yandji, Eka Astuty, Fitri Kadarsih Bandjar

Folia Medica Indonesiana

Candida infections are increasingly common worldwide and represent one of the leading causes of death after cardiovascular disease. There are three types of candida that often infect humans, namely Candida albicans, Candida tropicalis and Candida parapsilosis. In the standard treatment used, immunity and side effects of treatment have been found. Therefore, other treatment options are needed, one of which is by using mace (Myristica fragrans Houtt) which is a native plant of Maluku and has secondary metabolite compounds that can be antifungal agents. This study aims to test the ability of ethanol extract of mace nutmeg ( …

Group Counseling Deactivation Mode To Improve Psychological Well-Being Of Students, Muya Barida, Dian Ari Widyastuti, Yuanita Dwi Krisphianti, Aslina Ahmad, Nurul Hidayati Rofiah, Andriyani Andriyani, Riana Mashar, Emiko Saraswaty

Jurnal Kajian Bimbingan dan Konseling

Life moves dynamically, profoundly impacting adolescents and often causing deep anxiety due to numerous pressures. The gap between expectations and reality frequently exacerbates this anxiety. Ideally, adolescents should be equipped to manage their inner lives to prevent excessive anxiety, and individuals can better manage anxiety if they possess strong psychological well-being. This study aims to improve psychological well-being through a group counseling deactivation mode. The research applied an experimental research method with a one group pretest-posttest design. Participants consisting of junior high school students in Yogyakarta, selected through purposive sampling for their low psychological well-being levels. Data on psychological well-being …

Online Counseling In Improving Achievement Motivation Over The Last Decade: A Bibliometric Review, Shopyan Jepri Kurniawan, Bambang Dibyo Wiyono, Mohd. Aziz Zulazmi

Jurnal Kajian Bimbingan dan Konseling

This research aims to determine online counseling research trends to increase achievement motivation. The method used in this research is bibliometric analysis using VOSviewer. The data used is the Scopus database for the last 10 years. Research findings found that there were 4302 documents that met the specified criteria. The number of online counseling studies increased gradually over the 2013-2022 research period. The largest source of documents comes from 3691 articles. Meanwhile, the annual distribution of 100 or more citations will be the highest in 2022 with 16. The keyword ``achievement motivation'' is not included in the top 10 keywords, …

Quantitative Evaluation Of Tunnel Rock Mass Integrity Based On Mwd Technology, Zhang Kunmu, Peng Hao, Liang Ming, Han Yu, Song Guanxian

Journal of China & Foreign Highway

In tunnel construction,the quantitative evaluation of rock mass integrity heavily relies on information from the exposed face,and there are challenges when drilling data is used for integrity evaluation.To this end,this study introduced a novel method for quantitative evaluation of rock mass integrity during drilling,integrating numerical statistics with machine learning.A substantial dataset of digital drilling data was collected,covering three common types of rock mass integrity:relatively intact,relatively fractured,and fractured.Subsequently,a high-performance random forest model for the classification of rock mass integrity was developed through data preprocessing and hyperparameter optimization.The interpretability of the model ’s predictive results was enhanced using Shapley additive explanations (SHAP …

Mobile Markets And Farmers’ Markets: Evaluating Food Accessibility For Underserved Communities In The Bay Area, Rajeshwari Rajesh

Master's Theses

Studies indicate including farmers’ markets, mobile markets, and other local food systems improve fresh food access for low-income communities, especially when paired with food assistance programs that offer financial incentives. This study aims to evaluate mobile markets and farmers’ markets in the Bay Area using the five dimensions of food access: accessibility, availability, acceptability, affordability, and accommodation. The study is based on primary data collected from 173 in-person surveys at six mobile and eight farmers’ markets in the Santa Clara and Contra Costa counties. Key survey participants were market shoppers participating in food assistance programs. A mixed research methodology included …