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Prevalence And Risk Factors And Efforts To Reduce Dengue Fever And Dengue Hemorrhagic Fever Infections At Pku Muhammadiyah Gamping Hospital, Yogyakarta, Kusbaryanto Kusbaryanto, Abdurrasyid Bin Abdurrahman, Ekorini Listiowati, Yusuf Alam Romadhon, Aisyah Rosyida

Media Kesehatan Masyarakat Indonesia

The incidence of Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) has increased sharply in recent decades, making these infections endemic in several parts of the world. The purpose of this study was to analyze the prevalence, risk factors, and efforts to reduce DF and DHF infections at PKU Muhammadiyah Gamping Hospital, Yogyakarta. This study employed an observational cross-sectional design. The study sample consisted of patients diagnosed with DF or DHF at general hospitals in Yogyakarta between January 2019 and December 2023 who met the inclusion and exclusion criteria. Patients with a DF or DHF diagnosis but incomplete data were …

Evaluation Of The Efficacy Of Injection Of Platelet-Rich Plasma For The Management Of “Peyronie’S Disease” And Erectile Dysfunction, Marwan Abdulaziz Ibrahim

Al-Qadisiyah Medical Journal

Abstract: This study evaluates and determines the therapeutic effects of platelet-rich plasma injection for the management of Peyronie’s disease and erectile dysfunction. Patients & Methods: From March 2021 until March 2022, a prospective study was conducted on 50 patients with Peyronie’s disease, erectile dysfunction, and penile curvature less than 60 degrees (mild to moderate penile curvature). All participants were subjected to 8 repeated injections of PRP weekly in the dominant penile plaque, with follow-up over 6 months of collected data that included orientation of curvature, injection technique, and the results in both quantitative (i.e., curvature estimations) and qualitative (erectile state …

Comparative Analysis Of Papillary Thyroid Carcinoma And Benign Lesions; Immunohistochemical Diagnostic Markers And Their Gene Expression Correlation, Esraah Alharris, Samah Alkhalidy, Dina Saleh

Al-Qadisiyah Medical Journal

Background: Papillary thyroid carcinoma (PTC) incidence has increased globally, but it is unclear if this was because of an improvement in the patient’s knowledge or if the tumor was incidentally discovered. The microscopical features of the nuclei are the gold standard for diagnosing PTC. Many immunohistochemical markers have been used to accurately diagnose PTC, such as CK-19, TTF-1, HBME-1, ret, and S-100. Objectives: To assess the incidence of PTC in the Al-Qadisiyah governorate and examine the expression of several markers by immunohistochemistry in thyroid tissue biopsies. Materials and Methods: Two hundred and twenty surgically resected Thyroid glands were implanted in …

Balancing Diagnostic Sensitivity And Operational Efficiency In Mrsa Screening: A Study Of Pooled Multi-Site Swabs With And Without Viral Transport Media Using Genexpert®, Basem A. Jawa, Khulud A. Alhazmi, Khalid M. Alquthami, Ghazi S. Alkhaldi, Afnan O. Baharthi, Abdullah A. Marzogi, Saeed A. Badhdah, Eman A. Mulla, Daee M. Almalki, Atif A. Jahri, Ahmed A. Khan, Atiyah A. Alzahrany, Eman A. Bukhari, Tahani O. Roomy, Noha K. Alqurashi, Rehab G. Alqurashi, Rabab H. Moaminah, Fahd A. Alhejili, Majed M. Shaikh, Lamia H. Mohammed, Salwa N. Andejani, Mansour H. Alqasmi, Salman S. Alsharif, Fawaz F. Qasim, Ghadeer S. Areeshi, Abeer S. Alqarni, Baidaa S. Basudan

Journal of King Abdulaziz University: Medical Sciences

Methicillin-resistant Staphylococcus aureus (MRSA) remains a significant cause of healthcare-associated infections. Early identification of colonized individuals upon hospital admission is essential for effective infection control. This study aimed to evaluate the performance of pooled MRSA screening using the GeneXpert®system (Cepheid) under two conditions: with and without viral transport media (VTM). The goal was to assess the sensitivity of pooling strategies while minimizing reagent use, processing time, and laboratory workload. Swabs were collected from three anatomical sites, the axilla, groin, and nares, from newly admitted patients. Samples were pooled either with VTM or without VTM and then tested using the Xpert®MRSA …

Biofilm-Associated Infections: Mechanisms Of Formation, Resistance, And Emerging Therapeutic Strategies With Special Focus On Biofilm Inhibitors, Karem Ibrahem

Journal of King Abdulaziz University: Medical Sciences

Biofilms are complex, structured microbial communities enclosed within a self-produced extracellular matrix. This matrix allows them to adhere to a variety of surfaces, including medical devices and human tissues. The formation of biofilms poses a significant challenge in clinical settings due to their inherent resistance to antibiotics and to host immune defenses, thereby contributing to the persistence and chronicity of infections. In recent years, considerable attention has been directed towards the development of biofilm inhibitors as a promising therapeutic strategy to prevent biofilm formation, disrupt established biofilms, and enhance the susceptibility of biofilm-embedded bacteria to conventional antibiotics. The aim of …

Faktor-Faktor Yang Berhubungan Dengan Kualitas Hidup Pasien Geriatri Yang Menjalani Hemodialisis, Nurhidayat Mohammad, Czeresna Heriawan Soejono, Aida Lydia, Ikhwan Rinaldi, Muhammad Syafiq, Elizabeth Yasmine Wardoyo

Jurnal Penyakit Dalam Indonesia

Introduction. The decline in quality of life among geriatric patients undergoing hemodialysis has a negative impact on treatment adherence, physical functioning, dietary patterns, and mortality. This study was conducted to assess the quality of life of geriatric hemodialysis patients and its association with comorbidities, functional status, frailty, sarcopenia, nutritional status, depression, hemoglobin levels, hemodialysis vintage, vascular access, and hemodialysis adequacy.

Methods. This study employed a cross-sectional design with primary data collection. Consecutive sampling was used to recruit participants. The study was conducted at the hemodialysis units of Cipto Mangunkusumo National General Hospital (RSCM), Persahabatan National General Hospital (RSP), …

Rekam Medis Elektronik Berbasis Artificial Intelligence: Sudahkan Saatnya Digunakan?, Sukamto Koesnoe

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Korelasi Kadar Serum Vegf-A Dengan Rasio Albumin-Kreatinin Urin Pada Pasien Penyakit Ginjal Diabetik, Hannie Q. Syaiful, Drajad Priyono, Harnavi Harun, Arina W. Murni, Akmal M. Hanif, Eifel Faheri, Arnelis Arnelis, Vesri Yoga

Jurnal Penyakit Dalam Indonesia

Introduction. Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus, characterized by persistent albuminuria and a progressive decline in glomerular filtration rate (GFR), making it a leading cause of chronic kidney disease (CKD) and end-stage renal disease. Vascular endothelial growth factor-A (VEGF-A) is implicated in the pathogenesis of DKD, being overexpressed in the kidneys and contributing to increased vascular permeability, inflammation, and fibrosis. Albuminuria, an early indicator of renal damage in DKD, is a strong predictor of CKD progression and cardiovascular events. The urine albumin-to-creatinine ratio (UACR) is the recommended test for detecting and monitoring albuminuria. …

Kadar Transthyretin Plasma Pada Lanjut Usia Sarkopenia Dan Non-Sarkopenia, R. Ifan A. Fahrurozi, Rose D. Martini, Roza Mulyana, Arina W. Murni, Eva Decroli, Saptino Miro, Deka Viotra, Vesri Yoga

Jurnal Penyakit Dalam Indonesia

Introduction. Sarcopenia is a geriatric syndrome marked by an age-related decline in muscle mass, which is affected by protein intake. Transthyretin is a visceral protein used to evaluate nutritional status and acts as a positive regulator of muscle mass. This study aimed to assess the difference in plasma transthyretin levels between elderly groups with and without sarcopenia.

Methods. This was an analytical observational study with a cross-sectional approach. Subjects were elderly patients who visited the Internal Medicine Polyclinic of Dr. M. Djamil Hospital Padang and met the inclusion and exclusion criteria from August to September 2024. Subjects were …

Optimalisasi Rekam Medis Elektronik Berbasis Artificial Intelligence, Ikhwan Rinaldi, Wahyu Sulistiadi

Jurnal Penyakit Dalam Indonesia

Electronic medical records (EMRs) are essential to modern healthcare systems, yet their implementation continues to face challenges such as disruption of doctor–patient communication, administrative burden, and documentation structures misaligned with clinicians’ clinical reasoning processes. This narrative review aims to assess the limitations of conventional EMRs and examine the potential of artificial intelligence (AI) to improve documentation efficiency, accuracy, and overall clinical performance. The literature indicates that AI technologies, including machine learning, deep learning, and natural language processing, can automate documentation, streamline workflows, enhance decision support, and reduce physician burnout, thereby allowing clinicians to devote more attention to patient care. Nevertheless, …

Faktor Prediktif Post Dialysis Fatigue Sedang Pada Pasien Yang Menjalani Hemodialisis Reguler, Ivan Virnanda Amu, Maruhum Bonar H Marbun, Pringgodigdo Nugroho, Ikhwan Rinaldi, Hamzah Shatri, Nunuk Mardiana, Rudy Hidayat, Endang Susalit, Evy Yunihastuti, Dyah Purnamasari, Elizabeth Y. Wardoyo

Jurnal Penyakit Dalam Indonesia

Introduction. Fatigue is often found in patients with CKD-HD. Fatigue serves as an indicator of mortality and may be a viable target in a treatment strategy. Current research has not established the determinants of moderate PDF in individuals with CKD who are undergoing HD. Therefore, this study was conducted to prove the predictor factors of moderate PDF.

Methods. A retrospective cohort study in CKD-HD patients at Fatmawati Central General Hospital during the period of November-December 2024. The independent variables of this study are comorbidities, MIS, depression, intradialytic SBPV, dialysis vintage, UFG, IDWG, and anemia status. Primary data from …

Pengaruh Ivabradin Terhadap Variabilitas Detak Jantung Pada Gagal Jantung Dengan Fraksi Ejeksi Rendah Akibat Penyakit Jantung Koroner, Handy Kurnia, Charles Limantoro, Friska Anggraini Helena Silitonga, Andreas Arie Setiawan

Jurnal Penyakit Dalam Indonesia

Introduction. Heart failure is one of the major challenges in global health due to its significant contribution to morbidity and mortality. One of the pathophysiological aspects is autonomic nervous system dysfunction which can be monitored through heart rate variability (HRV) parameters. Ivabradine is a pharmacological agent that potentially improves the balance of sympathetic and parasympathetic tone. This study was designed to evaluate the impact of ivabradine administration on HRV parameters in heart failure with reduced ejection fraction (≤40%) due to coronary heart disease in Indonesian population.

Methods. This study used a quasi-experimental research type with a pretest and posttest …

Polisitemia Sekunder Pada Pasien Laki-Laki Muda Dengan Sindrom Nefrotik, Ariani Intan Wardhani, Pringgodigdo Nugroho, Ikhwan Rinaldi, Meilania Sarasawati, Monik Ediana Miranda, Agnes Stephanie Harahap

Jurnal Penyakit Dalam Indonesia

Polycythemia is a condition characterized by an abnormal increase in the total red blood cell mass and is classified into primary and secondary polycythemia. Secondary polycythemia occurs as a physiological response to tissue hypoxia or increased erythropoietin production, without intrinsic abnormalities in erythroid progenitor cells. This condition is rare, particularly when associated with nephrotic syndrome. This report aims to describe a case of secondary polycythemia associated with focal segmental glomerulosclerosis (FSGS). A 20-year-old man presented with generalized edema for five months prior to admission, accompanied by foamy urine. Physical examination revealed peripheral edema and minimal ascites. Laboratory investigations demonstrated massive …

Going Nuclear: Exploring Mtor’S Transcriptional Role In Regulating Estrogen Receptor Positive Breast Cancer, Alek S. Torres

NYMC Student Theses and Dissertations

Global changes in gene expression are orchestrated by an array of transcription factors regulated by both extracellular and intracellular signals. The mechanistic target of rapamycin (mTOR) is a protein kinase that ubiquitously mediates signaling networks across every cell type, in two active complexes, mTORC1 and mTORC2. By phosphorylating its downstream targets, these classically cytosolic complexes regulate protein homeostasis, metabolism, cell growth, proliferation and survival. However, evidence from prostate cancer studies reveals mTOR and its partners can occupy the nucleus, where its interaction with chromatin (in complex with transcription factors) has been shown to regulate gene expression at the level of …

Artificial Intelligence In Higher Education: A Bibliometric And Science-Mapping Analysis From An Institutional And Management Perspective, Kürşat Taştan, Nalan Sabır Taştan

Khazar Journal of Humanities and Social Sciences

This article maps the field of artificial intelligence in higher education (HEI-AI) from an institutional and management perspective. We draw on 52,270 peer-reviewed articles and reviews indexed in Web of Science and Scopus between 1959 and 2025. Using the bibliometrix package and its biblioshiny interface in R, we combine descriptive indicators with science-mapping techniques, including co-authorship and co-citation networks, keyword co-occurrence, thematic mapping and thematic evolution. The initial corpus of 94,845 records was cleaned by merging the two databases, removing duplicates and restricting the sample to full-length journal articles and reviews that explicitly address AI in higher education.

The results …

The Effectiveness Of Ais Systems In Developing The Announced Judicial Paper, Abdullah Essa Al-Rumh

Sultan Qaboos University Legal Studies Journal

This study aims to highlight the necessity of developing judicial papers to align with the use of multiple Artificial Intelligence Systems (AIS). It explores the role of AIS in enhancing the structure and delivery of judicial papers intended for the opponent’s awareness, focusing on the procedural requirements outlined in the Kuwaiti and Omani civil and commercial procedure codes. The research adopts a descriptive and analytical approach, examining the legal frameworks and solutions that facilitate the effective integration of AIS in the development and delivery of judicial papers.The study envisions the utilization of AIS to design virtual assistants capable of interpreting …

Moving From Feasible Solutions To Sustainable Systems In The Built Environment, Mohammed Ali Berawi, Mustika Sari, Perdana Miraj

CSID Journal of Infrastructure Development

The built environment plays a crucial role in global sustainability efforts. Buildings, infrastructure, and cities consume large amounts of energy and materials that shape social behavior, and lock in environmental impacts. Over the past two decades, research has produced a wide range of technical solutions to reduce these impacts. Renewable energy systems, energy-efficient buildings, alternative construction materials, and new construction methods are no longer experimental concepts. Many have proven technical and economic potential. Yet, real-world transformation remains slow and uneven. This gap suggests that sustainability challenges in the built environment are no longer driven by a lack of technology. Instead, …

Barriers To The Adoption Of Modular Construction Technology In South Africa, Mokete Matoba, Christopher Amoah

CSID Journal of Infrastructure Development

Construction, mining, and manufacturing are the most significant contributors to South Africa's GDP. While manufacturing and other industries utilise advanced technologies to enhance productivity, he construction industry continues to lag behind in technological adoption. This study examines the barriers that hinder the South African construction industry from leveraging the benefits of modular construction technologies (MCT). The study employed a quantitative research method, using closed-ended questions to collect data. The questionnaires were emailed to South African construction industry professionals selected through a combination of purposive and convenience sampling. A total of 98 questionnaires were distributed, of which 46 were returned. However, …

Urban Form Beyond Density: Shape Compactness Matters, Galuh Anisa Putri, Ahmad Gamal

CSID Journal of Infrastructure Development

Urban compactness has traditionally been measured through density, with population per area used as a core indicator of urban form. However, this method creates a limited view of what compactness means. Research shows that a compact city is not always a high-density city, and that increasing density does not automatically result in compact development. Compactness also involves the shape and structure of urban footprints, which influence how land is used and how a city functions. This paper presents a conceptual distinction between density and shape compactness, arguing that both are necessary to understand urban form. A qualitative literature review was …

Green Connectivity In Metropolitan Jabodetabek: Climate Change And The Challenge Of Urban Forest, Safira Maharani Putri, Hendricus Andy Simarmata

CSID Journal of Infrastructure Development

Urban areas in Indonesia, particularly the Greater Jakarta metropolitan region (Jabodetabek), are increasingly experiencing the adverse effects of climate change, such as the Urban Heat Island (UHI) phenomenon. Rapid urbanization has contributed significantly to rising greenhouse gas emissions and deteriorating environmental quality. Urban forests are one of the key solutions to mitigate these impacts; however, their spatial distribution in Jabodetabek remains suboptimal and poorly connected. This study uses NDVI as a proxy for urban forest density, where “urban forest” refers to vegetated areas within cities as defined by Presidential Regulation No. 60/2020. The research addresses the following question: How has …

Enhancing Health And Safety Practices In Construction Site In Developing Nations Through Technology Advancement In South Western Nigeria, Mubaraq Lawal, Abba Mahmud, Ismail Gbolahan Dere, Thankgod Agbo Owoicho

CSID Journal of Infrastructure Development

The construction sector plays a critical role in urban development and economic growth, yet it continues to face major challenges that threaten worker health and safety. Traditional safety measures are not always sufficient for the complex conditions found on construction sites, which creates a need for technology‑based solutions. This study investigates the relationship between technology adoption and health and safety practices in the construction industry in Lagos, Nigeria. The study identifies the major causes of site accidents, examines the level of technology use on construction sites, and reviews existing literature through both primary and secondary data. Primary data were collected …

Decision Framework For Enhancing The Adoption Of Alternative Infrastructure Funding Models In Ghana, Samuel Kojo Aidoo, Patricia Lindelwa Makoni

CSID Journal of Infrastructure Development

This paper examines the socio-economic and infrastructure conditions that determine Ghana’s readiness to adopt alternative infrastructure funding models (AIFMs) for sustainable road development. The objective of the study is to identify the macroeconomic and sectoral drivers of AIFMs’ adoption and to develop policy frameworks for the sustainable financing of infrastructure within Ghana’s context. Ordinary Least Squares (OLS) regression analysis is applied to annual data from 2003 to 2023 to examine the relationship between macroeconomic and infrastructure indicators and economic growth , which is used as a proxy for the viability of AIFMs. The results show that employment growth, educational attainment, …

Review: Archivist Actions, Abolitionist Futures: Reimagining Archival Practice Against Incarceration, Lauren Goodley

Provenance, Journal of the Society of Georgia Archivists

Review: Archivist Actions, Abolitionist Futures: Reimagining Archival Practice Against Incarceration, CLIR Pocket Burgundy series. Edited by Alison Clemens and Jessica Farrell. (Alexandria: Council on Library and Information Resources, 2025), 47 pages. Reviewed by Lauren Goodley.

Getting Started With Artificial Intelligence In 2025, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held November 25, 2025.

Cme For Family Mediators, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held September 19, 2025.

Advanced Microsoft Word Wizardry For Lawyers & Support Staff - Part 1, 2, 3, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held October 8, 22, 29 2025.

Home Ownership In Special Needs Trusts, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held December 2, 2025.

Civil Discovery_ The Tough Issues Argued, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held September 25, 2025.

Advanced Worker's Compensation, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held March 20, 2025.

Find Your Landing Zone - Planning For Life Beyond The Bar, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2025

Meeting proceedings of a seminar by the same name, held December 8, 2025.