Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 2521 - 2550 of 75720

Full-Text Articles in Entire DC Network

Fake News Y Redes Sociales: Cómo El Algoritmo En Torno A La Migración Afecta La Salud Mental, Maria F. Alarcon Dec 2025

Fake News Y Redes Sociales: Cómo El Algoritmo En Torno A La Migración Afecta La Salud Mental, Maria F. Alarcon

Capstones

Las redes sociales son la principal fuente de información para migrantes latinos en Estados Unidos, pero también son un terreno fértil para fake-news que afectan la salud mental y desinforman.


“Sin Tener Que Gastar”: Un Restaurante Gourmet En Nueva York Donde Pagas Lo Que Puedas, Oscar Alberto Flores Dec 2025

“Sin Tener Que Gastar”: Un Restaurante Gourmet En Nueva York Donde Pagas Lo Que Puedas, Oscar Alberto Flores

Capstones

Community Kitchen es un restaurante piloto gourmet en el Lower East Side de Nueva York que funciona bajo un modelo de “paga lo que puedas”, creado por el reconocido periodista gastronómico Mark Bittman. Ubicado en un vecindario marcado por una profunda desigualdad económica y altos niveles de inseguridad alimentaria, el proyecto busca demostrar que la comida de alta calidad puede ser accesible para personas de todos los ingresos. A través de un menú sostenible, precios flexibles, apoyo a agricultores locales —en su mayoría BIPOC— y salarios justos para jóvenes cocineros, Community Kitchen combina gastronomía, justicia social y comunidad. En …


Halt Under Threat Why Legislators Must Demand Compliance Before Change A Playbook For Action, Vanda Seward Dec 2025

Halt Under Threat Why Legislators Must Demand Compliance Before Change A Playbook For Action, Vanda Seward

Capstones

This playbook examines the implementation of New York State’s Humane Alternatives to Long-Term Solitary Confinement (HALT) Act and presents evidence demonstrating that the law has not been fully or consistently enforced by the New York State Department of Corrections and Community Supervision (NYSDOCCS). Drawing on findings from the New York State Inspector General, the Correctional Association of New York, the Justice Center, court rulings, and community testimony, the analysis documents persistent violations, including excessive and illegal use of solitary confinement, inadequate documentation, failures to protect vulnerable populations, and insufficient accountability for staff misconduct. The playbook critically evaluates the recommendations of …


What’S That Smell? It’S Climate Change!, Perry Gregory Dec 2025

What’S That Smell? It’S Climate Change!, Perry Gregory

Capstones

Climate change is going to make New York City smell worse. Reporter Perry Gregory breaks down the process of olfaction and explains how heat affects what we smell. The piece features a collage of voices of New Yorkers describing the current smell profile of the city. The report features insight from several Atmospheric Scientists into why New York City is getting hotter and more humid, and how those climate changes will make the existing smells of the city stronger, and worse. The most economically vulnerable New Yorkers, who cannot afford air conditioning to buffer them from heat, will be the …


Newsletter, December 2025, Cedar Oaks Guild Dec 2025

Newsletter, December 2025, Cedar Oaks Guild

Cedar Oaks Guild Newsletter

No abstract provided.


Design And Evaluation Of The Influence Of Mutual Induction On Microbial Electrolysis Cell Performance And Biogas Production, Ashley L. Blackwell Dec 2025

Design And Evaluation Of The Influence Of Mutual Induction On Microbial Electrolysis Cell Performance And Biogas Production, Ashley L. Blackwell

Civil Engineering ETDs

Microbial electrolysis cells (MECs) present a pathway for energy recovery in wastewater treatment by converting organic substrates into methane or hydrogen. Traditional MEC designs typically rely on physical electrode contacts and expensive materials, which restrict their scalability. This study introduces the first induction-based MEC that uses mutual inductance between an external copper wrap and an internal coil to generate a fluctuating electrical potential, removing the need for expensive electrodes. The induction-stimulated reactor showed faster total organic carbon removal and a higher CH4/CO2 ratio compared to a conventional anaerobic digester, indicating improved carbon-to-methane conversion, although total gas yield remained similar. Microbial …


Improving The Electrochemical Properties Of Mno2 By Doping With Fe For Water Splitting And Supercapacitor Application, Joseph Okwe Dec 2025

Improving The Electrochemical Properties Of Mno2 By Doping With Fe For Water Splitting And Supercapacitor Application, Joseph Okwe

Electronic Theses & Dissertations

An Abstract of the Thesis by

Joseph Okwe

These days when the issue of energy is talked about, it is usually more than just the usefulness of different types of energy. This topic now encompasses ways of generating and storing energy in the most efficient and sustainable way. For this reason, various research has shown that materials that are fabricated for the purpose of energy storage and conversion also find applications in other areas such as water splitting and supercapacitors. And so certain materials, when synthesized, can serve more than one purpose in either generating or storing energy. This project …


Stress During Adolescence: A Characterization Of Anxiety-Like Behavior, And The Mrna Expression Of Neuroimmune Factors, Clock And Stress Genes In Corticolimbic Areas., Annette Fernandez Oropeza, Annette K. Fernandez Oropeza Dec 2025

Stress During Adolescence: A Characterization Of Anxiety-Like Behavior, And The Mrna Expression Of Neuroimmune Factors, Clock And Stress Genes In Corticolimbic Areas., Annette Fernandez Oropeza, Annette K. Fernandez Oropeza

Biomedical Sciences ETDs

Adolescence represents a critical window of frontal cortex (FC) maturation and corticolimbic circuit refinement that supports stress and emotion regulation. Disruption of these processes by early-life insults such as prenatal alcohol exposure (PAE) or adolescent stress increases vulnerability to anxiety and mood disorders, in part through circadian–immune dysregulation. The circadian transcription factor Bmal1 and the proinflammatory cytokine tumor necrosis factor-alpha (TNFα) have emerged as key regulators of neuroimmune signaling and synaptic communication, yet their interactions across developmental risk contexts remain poorly understood. This dissertation examined the effects of mild adolescent isolation stress, with and without PAE, on anxiety-like behaviors and …


Corporeality In Choral Sound: Elements Of Consonant Diction Shaping Pre-Expressive Presence, Perceived Clarity, And Expression In English-Language Choral Music, Addison Walton Dec 2025

Corporeality In Choral Sound: Elements Of Consonant Diction Shaping Pre-Expressive Presence, Perceived Clarity, And Expression In English-Language Choral Music, Addison Walton

Dissertations, 2020-current

The genesis of this project stems from a lived experience performing with a professional choir, whose sung physical shaping of the English language—its crystalline clarity, profound expressivity, and the pre-expressive elements inherent in the delivery—was deeply and viscerally compelling. This overwhelming reaction was in response to their bodies; specifically, the sound their bodies produced that evoked a sense of corporeality, or tangible bodily presence. There was beauty to be found in the way their mouths physically formed the language, both within and removed from the semantic context.

This study sought to acknowledge those fleeting, pre-expressive moments in choral music and …


The Pathophysiological Role Of Mitochondrial Acid-Sensing Ion Channel 1a In Hypoxic Pulmonary Hypertension, Megan N. Tuineau Dec 2025

The Pathophysiological Role Of Mitochondrial Acid-Sensing Ion Channel 1a In Hypoxic Pulmonary Hypertension, Megan N. Tuineau

Biomedical Sciences ETDs

Pulmonary hypertension (PH) is characterized by increased pulmonary arterial constriction, pulmonary arterial remodeling, and right ventricular dysfunction. While metabolic and mitochondrial derangements are increasingly recognized as central pathogenic features, the underlying mechanisms and effectors are not yet fully understood. Acid-sensing ion channel 1a (ASIC1a) is a proton-gated cation channel involved in the development of chronic hypoxia (CH)-induced PH. ASIC1a represents a potential candidate involved in metabolic-mitochondrial dysfunction, as metabolic byproducts can act as ligands for ASIC1a. Additionally, ASIC1a has recently been identified as a mitochondrial ion channel involved in neuronal death following oxidative stress. Therefore, we hypothesize that ASIC1a functions …


The ‘Big Beautiful Bill’ Will Shrink New York’S Legal Workforce And Damage The Economy — Albany Must Act Now, Anthony W. Crowell Dec 2025

The ‘Big Beautiful Bill’ Will Shrink New York’S Legal Workforce And Damage The Economy — Albany Must Act Now, Anthony W. Crowell

Other Publications

No abstract provided.


The Dynamic Interplay Between Monovalent Salts And Ribosomal Protein S1 In Regulating Rna G-Quadruplex Structure, Chloe M. Martin Dec 2025

The Dynamic Interplay Between Monovalent Salts And Ribosomal Protein S1 In Regulating Rna G-Quadruplex Structure, Chloe M. Martin

Honors Theses

Many remarkable discoveries, especially in the last decade, have shown scientists just how important RNA is. In this study, the secondary structure of RNA, G-Quadruplexes, is the topic of interest and how they are affected by salts and S1 protein. To obtain the S1 protein it was transformed from E. Coli using a bacterial plasmid. The S1 protein was then purified from the bacteria through the use of many purification methods. The monovalent cationic salts used were LiCl and KCl which have different ionic radii size that contributes to the stability of RNA G-Quadruplexes. This stability was observed and affected …


Grappling With Parenthood In 2025, Elisa Muyl Dec 2025

Grappling With Parenthood In 2025, Elisa Muyl

Capstones

In 2024, I became a parent for the first time. Within the first year of my child's life, president Trump was elected for a second term and came into office on the back of a right-wing project to “restore” the American family as the central unit of American life. I knew instinctively that the values and policies this project espoused would not work for my family or many others. At the same time, I was grappling with a profound sense of social alienation and the lack of structural support for new parents, exacerbated by the way that community is sustained …


A Phenomenological Study Of The Lived Experiences Of Implementing An Education Model From School Leaders’ Perspectives, Jackie Marie Cusimano Phd Dec 2025

A Phenomenological Study Of The Lived Experiences Of Implementing An Education Model From School Leaders’ Perspectives, Jackie Marie Cusimano Phd

Teacher Education, Educational Leadership & Policy ETDs

A high school science teacher asked the question, “Why not make every class an elective?” He noticed that when his high school students were required to take a course, such as biology, the attendance and participation lacked when compared to his elective course of forensic biology. Both classes covered the same science standards. This question led him to applying for a public charter license and ultimately opening the first Choice Charter School in Albuquerque, New Mexico, in 2014. Choice Charter Schools follow the created Choice Charter Education Model, which is based on William Glasser’s Choice Theory (Glasser, 1998). Since the …


Security Blanket: An Idea Of "Home" Across The Housing Spectrum, Willa D. Odefey Dec 2025

Security Blanket: An Idea Of "Home" Across The Housing Spectrum, Willa D. Odefey

Capstones

Security Blanket: an idea of "home" across the housing spectrum addresses the logistical and emotional gaps left by policy-makers who prescribe a one-size-fits-all approach of housing to New York City’s houseless crisis. Independent living can be a major adjustment for people who have never lived on their own (eg. lived with parents, were formerly incarcerated, were in long-term hospital care), and shelters do not adequately prepare residents for the life-building steps after move-out. I asked New Yorkers experiencing homelessness where they are now, what home means to them, and what it would or has taken to ground themselves as they …


Krasg12d Mutation Promotes Pancreatic Tumorigenesis By Suppressing Sirtuin Three Via The Guanine Nucleotide Exchange Factor Rcc1, Taoyi Mai, Mengwen Wang, Ya Qiu, Wenhua Lu, Hongyu Wu, Shuna Chen, Paul J Chiao, Peng Huang Dec 2025

Krasg12d Mutation Promotes Pancreatic Tumorigenesis By Suppressing Sirtuin Three Via The Guanine Nucleotide Exchange Factor Rcc1, Taoyi Mai, Mengwen Wang, Ya Qiu, Wenhua Lu, Hongyu Wu, Shuna Chen, Paul J Chiao, Peng Huang

Faculty, Staff and Student Publications

KRASG12D mutation is a prevalent gain-of-function mutation that drives pancreatic cancer tumorigenesis, but the underlying mechanisms that promote KRAS-induced cell proliferation and tumor formation remain elusive. To uncover the molecular pathways that facilitate KRASG12D-driven malignant transformation, we measured the transcriptomic alterations at various time points after induction of KRASG12D expression in human pancreatic normal epithelial cells. KEGG pathway enrichment of the differentially expressed genes (DEGs) showed that the major DEGs were located in pathways that regulate nicotinate/nicotinamide metabolism, TNF signaling, and microRNAs associated with cancer. Among these molecular alterations, the NAD-dependent deacetylase gene SIRT3 was significantly down-regulated by KRASG12D. Conversely, …


“Bridging The Gap To Midwave Infrared Event-Based Sensors: Design, Sensitivity, And Radiation-Hardness Characterization Of A Single-Pixel Iii-V Event-Based Infrared Sensor For Space Applications, Zinah M. Alsaad Dec 2025

“Bridging The Gap To Midwave Infrared Event-Based Sensors: Design, Sensitivity, And Radiation-Hardness Characterization Of A Single-Pixel Iii-V Event-Based Infrared Sensor For Space Applications, Zinah M. Alsaad

Electrical and Computer Engineering ETDs

Event-based sensing presents a revolutionary paradigm shift for next-generation space surveillance systems, where power consumption is an ever-worsening constraint as temporal resolution demands increase. In addition to reduced power consumption, low latency, and wide dynamic range, the event-based sensor fundamentally only produces data when there is a change in illumination from which events are generated; no data is produced if the scene remains static. With their event-based datastream being inherently focused on the dynamic information of the scene, they are particularly well-suited to machine vision and autonomous sensing applications. While these sensors have many compelling advantages, there are presently no …


Knowledge Production As Identity Expression: A Third-Space Perspective On Sustainable Careers, Alicja Syska Dec 2025

Knowledge Production As Identity Expression: A Third-Space Perspective On Sustainable Careers, Alicja Syska

School of Law, Humanities and Social Sciences

This conceptual paper advances our understanding of sustainable careers by focusing on the knowledge creation activities of third-space practitioners in higher education. Specifically, we apply and extend the Process Model of Sustainable Careers to examine how different forms of knowledge production in three different institutional and national contexts – writing for publication, practice-based expertise, and curriculum development – contribute to career sustainability at the intersection of academic and professional/administrative roles and domains. The critical element of this extension is ‘identity expression’ in the form of knowledge production, which acts as an integrating mechanism that flows through and connects the original …


From Plaque To Tumour: Follicular Neoplasm Arising In Congenital Nevus Sebaceous, Tasneem Hamed Al Salmani, Suad Al Jahdhami, Nawaf Al Muqaimi, Ayida Al Khalili Dec 2025

From Plaque To Tumour: Follicular Neoplasm Arising In Congenital Nevus Sebaceous, Tasneem Hamed Al Salmani, Suad Al Jahdhami, Nawaf Al Muqaimi, Ayida Al Khalili

Sultan Qaboos University Medical Journal

No abstract provided.


Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana Dec 2025

Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana

2020-Current year OA Pubs

Intermittent fasting (IF) has gained attention as a potential intervention for cardiometabolic health, though its long-term effects remain unclear. In this randomized clinical trial, we assessed the impact of 6 months of IF on body composition, cardiovascular risk factors, and related molecular pathways in middle-aged (30-65 years) men and women with overweight (BMI 24.8-35 kg/m²). In this trial, 41 participants were randomized to either an intermittent fasting (IF) intervention or to maintain their habitual diet. The primary outcome (circulating CRP concentration) was previously reported; here, we present exploratory analyses focusing on metabolomic and transcriptomic responses. IF led to an 8% …


Revisiting The 2015 Mds Diagnostic Criteria For Parkinson Disease: Insights From Autopsy-Confirmed Cases, Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder Dec 2025

Revisiting The 2015 Mds Diagnostic Criteria For Parkinson Disease: Insights From Autopsy-Confirmed Cases, Susan H Fox, Daniel G Luca, Ronald B Postuma, Roongroj Bhidayasiri, Francisco Cardoso, Gabor G Kovacs, Regina Katzenschlager, Claudia Trenkwalder

2020-Current year OA Pubs

The 2015 International Parkinson and Movement Disorder Society (MDS) Diagnostic criteria for Parkinson Disease are based on expert consensus opinion and defines core motor features, 'Absolute Exclusion Criteria' and a balance of 'Supportive Criteria' and 'Red Flags'. To assess validity of each criterion in pathologically-confirmed cases, a scoping literature review between 1988-2024 using search terms for clinicopathological PD and atypical parkinsonian disorders identified 28 articles. Supportive criteria were higher in PD, with excellent levodopa response and rest tremor most useful. Absolute exclusion criteria and red flags were present more often in atypical parkinsonian disorders. However, supranuclear gaze palsy, rapid progression …


Protein-Nucleic Acid Language Model-Assisted Design Of Precise And Compact Adenine Base Editor, Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang Dec 2025

Protein-Nucleic Acid Language Model-Assisted Design Of Precise And Compact Adenine Base Editor, Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang

Faculty, Staff and Students Publications

Adenine base editors (ABEs) are powerful tools for gene therapy. However, efficient version of ABEs (e.g. ABE8e) always induce excessive bystander and off-target editing events and are large in size, hindering their potential in clinical disease treatment. Here, we develop a pre-trained Protein-Nucleic Acid Constrained Language Model to design ABE8e with high activity, reduced editing window and decreased size. By further engineering, the smallest ABE8e- PNLM-pcABE- with a 27% size reduction, exhibits high activity, precise 3-nt editing window, and reduced off-target events near background level in HEK293T cells. Compared to ABE8e, PNLM-pcABE has up to 133.5-fold precision improvement in pathogenic …


Recreating Fiber Recruitment With Fiber Recruitment Using Additive Manufacturing, Natalia D. Mciver Dec 2025

Recreating Fiber Recruitment With Fiber Recruitment Using Additive Manufacturing, Natalia D. Mciver

Biomedical Engineering ETDs

Injured ligaments are often repaired with tendon grafts which may over or under constrain the joint; there is a need for an artificial graft option with the mechanical properties of a native ligament. Crimped fibers within ligaments allow for recruitment which means the viscoelastic properties of stress relaxation and creep are not inversely related. A feasibility study using ACLs and large-scale crimp models to study viscoelasticity, led to an in-depth analysis of the scapholunate interosseous ligament. Using the Modified Kelvin spring-dashpot model, for describing viscoelasticity with a variable stiffness property (time dependent fiber recruitment), we defined the relationship between creep …


Methodology For The Pediatric Dose Optimization For Seizures In Emergency Medical Services (Pedidose) Study, Manish I Shah, Kathleen M Adelgais, James M Chamberlain, Henry E Wang, Lindsey A Morgan, James J Riviello, Rana R Said, Joseph E Sullivan, Kimia F Ghaffari, Kathryn M Kothari, Mohsen Saidinejad, Robert A Lowe, Raymond L Fowler, Catherine R Counts, Claudia R Morris, Jonathan R Studnek, Nancy K Glober, Caleb E Ward, Brian M Clemency, Nicholas Patrick, Rachel D Munn, Graham M Brant-Zawadzki, Christian Martin-Gill, Daniel K Nishijima, Kevin Li, Neomi Sepulveda, John M Vanburen Dec 2025

Methodology For The Pediatric Dose Optimization For Seizures In Emergency Medical Services (Pedidose) Study, Manish I Shah, Kathleen M Adelgais, James M Chamberlain, Henry E Wang, Lindsey A Morgan, James J Riviello, Rana R Said, Joseph E Sullivan, Kimia F Ghaffari, Kathryn M Kothari, Mohsen Saidinejad, Robert A Lowe, Raymond L Fowler, Catherine R Counts, Claudia R Morris, Jonathan R Studnek, Nancy K Glober, Caleb E Ward, Brian M Clemency, Nicholas Patrick, Rachel D Munn, Graham M Brant-Zawadzki, Christian Martin-Gill, Daniel K Nishijima, Kevin Li, Neomi Sepulveda, John M Vanburen

Faculty, Staff and Student Publications

Background: Seizures are one of the most common reasons for emergency medical services (EMS) activation for children, and current EMS practice results in underdosing and delayed delivery of anti-seizure medication. A prehospital evidence-based guideline recommends using intranasal or intramuscular midazolam as first-line treatment for pediatric seizures. Despite attempts to implement these guidelines, one-third of children having a paramedic-witnessed seizure have ongoing seizures on emergency department (ED) arrival; this may be due to inadequate or delayed midazolam dosing. Replacing the error-prone, sequential calculations with age-based midazolam dosing may be simpler, faster, and more effective without compromising safety. The objective of this …


Prevention Of Suicide As Perceived By Educated Adults In Ondo Metropolis, Ondo State, Nigeria, Margaret Kehinde Soetan Dec 2025

Prevention Of Suicide As Perceived By Educated Adults In Ondo Metropolis, Ondo State, Nigeria, Margaret Kehinde Soetan

Buletin Konseling Inovatif

This study investigated prevention of suicide as perceived by educated adults in Ondo metropolis, Ondo State, Nigeria. Descriptive survey research design was adopted for this study. Population of the study consisted of all educated adults in Ondo metropolis, Ondo State. The sample comprised two hundred (200) educated adults randomly selected from the metropolis. Structured questionnaire was used as instrument to collect data for the study. Data collected was analysed using mean, ranking, t-test and analysis of variance (ANOVA). The results revealed the perception of prevention of suicide as giving people hope for a better life after current problems are resolved, …


¿Cómo Se Dice, "Liberty And Justice For All Cannot Exist Without Equal Access For All" En Español?, Turner Denise Reynolds Dec 2025

¿Cómo Se Dice, "Liberty And Justice For All Cannot Exist Without Equal Access For All" En Español?, Turner Denise Reynolds

Kentucky Law Journal

No abstract provided.


Like Balance On Ice: Towards A New Approach To The Open And Obvious Doctrine Under Kentucky Law, Hayden T. Crosby Dec 2025

Like Balance On Ice: Towards A New Approach To The Open And Obvious Doctrine Under Kentucky Law, Hayden T. Crosby

Kentucky Law Journal

No abstract provided.


Just A Place Or A Just Place?: Domestic Violence, Urban-Rural Differences, And Access To Justice, Cassie Chambers Armstrong Dec 2025

Just A Place Or A Just Place?: Domestic Violence, Urban-Rural Differences, And Access To Justice, Cassie Chambers Armstrong

Kentucky Law Journal

No abstract provided.


Prosecutorial Discretion And Digital Democracy, Erin Sheley Dec 2025

Prosecutorial Discretion And Digital Democracy, Erin Sheley

Kentucky Law Journal

No abstract provided.


Founder Worship, Effective Altruism, And Corporate Governance, Jennifer S. Fan, Xuan-Thao Nguyen Dec 2025

Founder Worship, Effective Altruism, And Corporate Governance, Jennifer S. Fan, Xuan-Thao Nguyen

Kentucky Law Journal

No abstract provided.