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Endocrine Disruptors And Children's Health, Ersen Karakiliç, Durmuş Doğan, Emre Sedar Saygili

Turkish Journal of Medical Sciences

Endocrine-disrupting chemicals (EDCs) are environmental contaminants that disrupt hormonal regulation by mimicking, inhibiting, or modifying endocrine signaling pathways. EDCs are commonly present in plastics, pesticides, industrial byproducts, and personal care products and pose substantial health risks, particularly to vulnerable groups such as infants and children. Early-life exposure is especially concerning due to the developing detoxification systems, the immaturity of the blood–brain barrier, and the ongoing organ differentiation, making these periods highly susceptible to EDCs’ harmful effects. Moreover, exposure during critical developmental periods, such as sex differentiation and neurodevelopment, can lead to significant long-term developmental impairments that persist into later life.Perinatal …

A Play-Based Stoic Intervention: Preventive Pedagogy For Childhood Resilience, Ross William Podyma Mr

International Journal of Playwork Practice

Rates of reported childhood mental health difficulties have risen markedly in recent years, prompting a policy emphasis on early identification and rapid referral to clinical services. While such responses are vital for acute and complex presentations, there is growing concern that they may contribute to an over-pathologising of normative developmental experiences. Everyday challenges that once functioned as opportunities to build resilience are increasingly framed as early symptoms of mental disorder. This risks undermining children’s ability to cope adaptively with adversity, inadvertently fostering reliance on external intervention.

Since its inception in 2012, Sporting Communities CIC has been embedded in schools and …

Teachers’ Views About School Playtime: A Systematic Literature Review, Misbah Khan, Cathy Atkinson

International Journal of Playwork Practice

School playtime exists in varying forms across the world, and there is an extensive evidence-base pointing to its beneficial effects on children. The United Nations Convention on the Rights of the Child (UNCRC) recognises these benefits and provides clear guidance to international organisations, including schools, on protecting children’s right to play. However, legislative and societal pressures have led to teacher practices which facilitate the erosion of school playtime. Teachers’ beliefs and their practices are considered to be interlinked and therefore the aim of this systematic literature review is to consolidate existing research on teachers’ views about playtime and consider how …

Pioneering Insights Into The Complexities Of Salt-Sensitive Hypertension: Central Nervous System Mechanisms And Dietary Bioactive Compound Interventions, Renjun Wang, Bo Xu, Xiping Liu, Qi Guo, Gregory Miodonski, Zhiying Shan, Dongshu Du, Qing Hui Chen

Michigan Tech Publications

Salt-sensitive hypertension (SSH) is an important and common subtype of hypertension, whose pathogenesis involves multi-level regulation, including the central nervous system (CNS), metabolic stress, and epigenetics. Dietary bioactive compounds have emerged as a research hotspot for SSH intervention due to their safety and multi-target effects. Although existing studies have focused on the CNS regulation of SSH or the role of individual dietary components, there is a lack of comprehensive analysis integrating multiple mechanisms, systematically summarizing multiple compounds, and incorporating a clinical translation perspective. This review first outlines the mechanisms of CNS pathways, endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and epigenetic …

Minutes From December 17 2025, University Senate

University Senate Minutes

Minutes from December 17 2025 University Senate Meeting

Short-Term Tillage Effects On Greenhouse Gas Emissions And Global Warming Potential From Soybean In Southeast Arkansas, Lauren Gwaltney, Kristofor R. Brye, Della Lunga Diego, Jonathan B. Brye, Trenton Roberts, Samuel B. Fernandes, Michael B. Daniels

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Reduced tillage (RT) is a common conservation agriculture practice, generally regarded to be a valuable greenhouse gas (GHG) mitigation approach through increasing soil carbon (C) stocks. However, direct GHG measurements from RT compared to conventional tillage (CT) treatments can vary greatly depending on site-specific soil properties and management practices. The objective of this study was to evaluate the short-term effects of RT on soil-to-atmosphere carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) fluxes and emissions, global warming potential (GWP), yield, and emissions intensity (EI) throughout the 2024 soybean (Glycine max) growing season in a southeast Arkansas production field. Bulk …

Unraveling The Drivers Of Inequality In Maternal Healthcare Utilization In Indonesia: A Decomposition Analysis, Wji Wahyuningsih, Kemal N. Siregar, Syifa Nurhakiki

Jurnal Ekonomi Kesehatan Indonesia

This study assessed socioeconomic inequalities in maternal healthcare utilization in Indonesia and identifies key factors driving these inequalities. We used data from 2013 and 2023 Indonesian Health Surveys, comprised of a total unweighted sample of 15,638 and 9,923 women aged 15-49 in the 2013 and 2023, respectively. Concentration index (CI) measured wealth-based inequality, and decomposition analysis identified primary drivers of inequalities in maternal healthcare access. Overall maternal healthcare service utilization has increased, but significant inequalities persist. Antenatal care showed minimal improvement, with the CI rising from 0.059 to 0.079, indicating a persistent higher socioeconomic distribution. Facility-based deliveries improved, with the …

Behavior Analytic Food Reinforcement Use And Guidelines In Interventions For Children With Autism, Christopher Rogers

Electronic Theses and Dissertations 2020 - Present

Reinforcers create opportunities to increase behaviors in applied behavioral analysis, with healthy and unhealthy foods offering high reinforcing value. The use of food raises ethical and health concerns, so researchers and behavior analysts often avoid food reinforcement altogether. Kronfli et al. (2024) indicate healthy food alternatives bring about similar rates of responding as snack foods, potentially reducing ethical and health concerns. This research presents the question: To what degree are food reinforcers used in behavioral interventions for children with autism spectrum disorder? This review analyzes behavioral research articles containing the words “food,” “edible,” “autism,” and “children” in the context of …

The Conditional Nature Of The Value Premium: Interaction And Cross-Sectional Evidence Across Market Regimes, Samuel L. Klein

Honors Thesis

This thesis examines why value-based investment strategies generate strong returns in some environments yet weaken or collapse in others. Regressions test whether the performance of the book-to-market ratio depends on the investor’s perception of financial health as defined by F-Score and accruals. Across additive regressions, interaction models, cross-sectionals, and heatmap visualizations, a consistent mechanism emerges. The book-to-market effect is strongest when financial information is neither highly reliable nor severely distressed. In these “moderate-quality” environments, investors struggle to fully distinguish the transitory components of earnings from their persistent counterparts. This makes valuation ratios particularly influential. Accrual intensity and financial strength jointly …

Acer 2024-2025 Annual Report, Australian Council For Educational Research (Acer)

ACER Annual Reports

For more than 95 years, ACER has been driven by a single purpose – to improve learning for all. Founded in 1930, ACER began as a small team of researchers determined to bring rigour and evidence to education and assessment. Over the decades, that commitment has evolved into a global mission – combining world-class assessment and research to help learners, educators and systems understand what works in education, and why.

Donne Buck: All Work, All Play, William Newton

International Journal of Playwork Practice

Donne Buck (1934-2023) was a New Zealand-born pioneer of British adventure play. He recorded his work, including on some of the earliest London playgrounds, in exquisite detail, resulting in an exceptional archive of his achievements now held by the V&A Museum. This article offers a brief summary of his career as a play practitioner and highlights his influence on the field of playwork.

The ‘For Youth’ Page: Analyzing Tiktok Content Feeds For College-Aged Users, Hadiyah Mohamed

Honors College Theses

This study analyzes the content college-aged users encounter on TikTok’s “For You” page to understand the ways platform design and user-generated content shape prolonged engagement. Existing research frames doomscrolling largely as a compulsive behavior driven by algorithmic design, often overlooking the role of content itself and why it resonates with young adults. Through qualitative content analysis, 150 videos were collected across three TikTok accounts: scrolling from a personal account, a neutral new account, and a new account under the #CollegeTok tag. Videos were rigorously coded in a spreadsheet for narrative descriptions, topics, captions, hashtags, and tone to capture the themes …

Surgical Revision In The Presence Of An S. Aureus Infection Increases Virulence Factor Expression And Activates A Multi-Tissue Inflammatory Response, Carly J. Smith, Arianna J. Moniodes, Amanda R. Watkins, Autumn G. Melvage, Thomas P. Thompson, Eirene Choi, Abigail A. Lucas, Brendan F. Gilmore, Thomas P. Schaer, Noreen J. Hickok, Theresa A. Freeman

Department of Orthopaedic Surgery Faculty Papers

Replacing implanted medical hardware due to infection often requires one or more revision surgeries. Each surgery triggers a tissue injury response and disrupts the established bacterial biofilm. However, the complex tissue response to reinjury and biofilm disturbance is not well understood. Our results show that with an existing infection, immunological niches such as the bone marrow, lymph nodes, and circulating blood further upregulate pro-inflammatory programs in response to revision. Rather than reducing bacterial burden, this heightened inflammation provokes virulence factor expression and tissue damage, including bone osteolysis and muscle fibrosis. While muscle fibrosis appears transient and begins resolving by 14 …

Workplace Incivility And Well-Being: A Moderated Mediation Analysis Of Loneliness And Supervisor Support, Marie Rylance

Master's Theses

By building on previous research and addressing calls to examine the growing epidemic of loneliness, this study investigated how workplace incivility affects employee well-being and workplace outcomes, with attention to the roles of loneliness and supervisor support. Guided by the Conservation of Resources theory, workplace incivility was conceptualized as a resource-draining process that fosters stress states such as loneliness. A key contribution of this study was examining the process through which incivility impacts employees, by testing loneliness as a mediating mechanism and supervisor support as a potential moderator. Using data from 178 participants, regression and mediation analyses were conducted, as …

Minerals, Critical Minerals, And Strategic Minerals In Alaska: Challenges And Opportunities, Bob Loeffler, Brett Watson, Rebecca Van Wyck

ISER Reports

This report examines the challenges and opportunities involved in increasing Alaska’s role in the U.S. critical minerals industry. It describes how critical minerals are defined, and which of those have been mined today, have been mined in the past or are likely to be mined in the near future. It describes how market conditions and geology affect Alaska’s opportunities to increase critical mineral production. It also describes how Alaska’s benefits from critical mineral production are the same as those from any mineral production: jobs, income, and taxes. Finally, the report makes recommendations for expanding critical mineral production.

On Lethality: Toward A More Complete Definition And Formation Of The Lethality Framework, John M. Hinck, Robert S. Hinck, Jayson A. Altieri, David R. Jarnot

The US Army War College Quarterly: Parameters

This article argues lethality should be conceptualized as a holistic and regenerative process in which adversarial militaries prepare for, adapt to, and sustain the application of force in conflict. Whereas the literature on lethality is widening to include the human war fighter, attempts to define and measure lethality have proven problematic—a struggle this article seeks to remedy. Drawing on historical, doctrinal, and interdisciplinary perspectives, the authors argue that lethality includes the capacity to kill and elements of learning and adaptation. The proposed lethality framework offers policy and military practitioners a model for assessing and operationalizing lethality in military education, leadership …

Esophageal Gastrointestinal Stromal Tumor With, Bradley Kruithoff, Lauren Beard, David Liebner, Swati Satturwar, Matthew Lamb

Oncology Articles

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms typically involving the upper gastrointestinal tract. Most GISTs are driven by activating mutations in the KIT or PDGFRA genes, which are primary molecular markers for diagnosis and treatment. In addition, CD117 and DOG1 (discovered on GIST 1) are important immunohistochemical diagnostic markers of GISTs. Esophageal GISTs are exceptionally rare, and those driven by BRAF gene fusions are even more uncommon. This report describes a 69-year-old woman who underwent surgical resection of an esophageal GIST harboring an MKRN1-BRAF gene fusion, offering insight into future treatment and surveillance strategies.

Enfrentando El Patriarcado: La Voz, El Espacio Femenino Y Lo Sobrenatural En Mexican Gothic De Silvia Moreno-Garcia, Raquel Macias Del Valle

Theses and Dissertations

This thesis explores the crossroads of gender, space, and the supernatural in Mexican Gothic (2020) by Silvia Moreno–Garcia, examining how the novel challenges patriarchal structures through its protagonist, Noemí Taboada. Utilizing feminist theory, spatial analysis, and studies on the supernatural, this research demonstrates how Moreno–Garcia constructs a narrative in which female expression and connection are central to reinstating the feminine self as a subject. The novel presents High Place, the ancestral mansion of the Doyle family, as a space that embodies patriarchal control. Drawing on Gastón Bachelard’s The Poetics of Space and Marc Olivier’s Household Horror, this study examines how …

Using Rhizobia Seed Coatings And Soil Amendments To Combat Herbicide Toxicity For Native Legume Establishment, Ryan Matthew Glover

Theses and Dissertations

Dryland ecosystems face widespread degradation from historical mismanagement, climate change, and invasive species proliferation. Although herbicides effectively control invasive annual weeds, they often suppress the establishment of desirable perennial species, limiting restoration success. Legumes enhanced with rhizobia inoculants offer a promising approach to overcome these challenges by facilitating nitrogen fixation, improving soil microbial communities, and potentially mitigating herbicide stress. We conducted paired greenhouse and field experiments to evaluate whether rhizobia seed coatings improve the establishment of three legume species Astragalus cicer (Cicer Milkvetch), Onobrychis viciifolia (Sainfoin), and Medicago sativa (Alfalfa), in soils treated with imazapic and glyphosate. In the greenhouse, …

Dnp Final Report: Hypertension Education In The Primary Care Setting, Michelle L. Sanders

DNP Final Reports

Background: Hypertension is a significant concern at the global, national, and local levels. If left untreated or improperly managed, it can result in severe health issues. Many patients in primary care settings have difficulty controlling their hypertension, which can lead to significant complications.

Practice question: What strategies can be implemented to help patients in primary care manage their hypertension more effectively?

PICOT: For patients age 18+ in a rural primary care clinic (P), how does the use of an education pamphlet (I) compared to no pamphlet use (C) affect patient management of hypertension(O) in three months? (T)

Body of …

Microbial Communities Of Selected Regions Of The Deep Springs Lake Aquifer System, Rania Zaki, Emma Bourne, Andrew Storino, Jay Nadeau

Physics Faculty Publications and Presentations

Deep Springs Lake is a small, isolated, highly alkaline soda lake in Inyo County of Eastern California, USA. It is a seasonally filled salt lake or playa, and is part of a closed aquifer system. Such closed systems are globally rare, occurring only in arid zones where annual evaporation is greater than annual rainfall. Deep Springs Lake’s hydrology and geology have been well studied, and it is home to a unique toad species, but its microbiome remains unexplored. Here we perform 16S, 18S, and ITS amplicon sequencing of the lake water, dried salt crust at the edges the lake, and …

Beyond The Standard: A Sociolectal And Probabilistic Turn In Philippine English Phonology, Teri An Joy G. Magpale

Journal of English and Applied Linguistics

This article advocates for probabilistic approaches as a key framework for understanding Philippine English (PhE) phonology, arguing that they reveal socially conditioned variation that traditional descriptive models overlook. Tracing five decades of research, it critiques early standardization efforts and studies centered on scripted speech and elite norms, and highlights the sociolectal turn initiated by Tayao (2004). The discussion foregrounds recent methods that combine instrumental phonetics with constraint-based frameworks, including Optimality Theory (OT) and Maximum Entropy grammar (MaxEnt), to model gradient variation across acrolectal, mesolectal, and basilectal speakers. By synthesizing findings on segmental features, phonotactic patterns, and speech rhythm, the article …

The Relationship Between K-12 Public School Funding, Per Pupil Expenditures, And Student Achievement, Regina R. Frazier-Bagley

Walden Dissertations and Doctoral Studies

Public school district leaders are challenged with funding K-12 education that creates the desired student academic performance. Grounded in student-based budgeting theory, this quantitative ex post facto study aimed to investigate the relationship between K–12 public school funding, per-pupil expenditures, student achievement, and graduation rates in Georgia. The study included secondary data from 51 North Georgia public school districts for the 2018–2019 school year. Multiple regression analysis was completed to examine the relationship between the independent variables—state funding, per-pupil expenditures, and academic achievement in math, science, and language arts—and the dependent variable: graduation rates. The results of the analysis were …

Reducing The Use Of Erythropoiesis-Stimulating Agents In Hemodialysis Patients, Myriamme Neree

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice project was a quality improvement (QI) initiative. Nephrologists were inconsistent in ordering iron studies and sometimes delayed the initiation of erythropoiesis-stimulating agents (ESAs) on admission to the inpatient site. These delays often led to suboptimal outcomes. The practice-focused question guiding the project asked whether a nurse-driven iron protocol would improve adherence to anemia management guidelines. The project’s purpose was to evaluate the impact of the evidence-based nurse-driven protocol. I used descriptive and inferential statistics for data analysis. Findings demonstrated a statistically significant improvement in the timely completion of iron studies and in intravenous (IV) iron …

Recruitment, Retention, And Retirement Plan Structure: Evidence From Teachers, Noah Burke, Brock Wilson

ISER Reports

In 2006, the State of Alaska closed its defined benefit retirement plan and required all newly hired public education employees—mostly teachers—to join a defined contribution plan. This paper examines whether that change in pension structure affected recruitment or retention in Alaska’s public education workforce.

Osteoprogenitor Cells From Non-Regenerative Bone Show Greater Resistance To Cellular Stress Than Those From Regenerative Bone, Joshua Broussard, Sylvia Culpepper, Tyrel Long, Alexander J. Trostle, Robert J. Tower, Mimi C. Sammarco, Jennifer Simkin

School of Medicine Faculty Publications

INTRODUCTION: Bone regeneration following injury depends on osteoprogenitor cells derived predominantly from the periosteum. Incomplete regeneration has been attributed to both cell-extrinsic factors (e.g., environment, inflammation, mechanical instability) and cell-intrinsic factors (e.g., impaired proliferation or differentiation of stem cells). In the digit amputation mouse model, amputation through the third phalanx (P3) supports complete regeneration, while amputation through the second phalanx (P2) results in callus formation and scarring. Periosteal cells are known to be the major contributing cell source for repair and regeneration. Yet the healing outcomes of P2 and P3 amputations are significantly different. This study tests whether P2 and …

Endocrine Disrupting Chemicals And Adrenal Gland​, Gülay Şi̇mşek Bağir, Melek Eda Ertörer

Turkish Journal of Medical Sciences

Endocrine disrupting chemicals (EDCs) are exogenous compounds that have hormone-like effects inside the body. Endocrine disruptors can affect adrenal glands in humans and animals. Adrenocortical dysfunction related to chemical exposure has been reported in the literature.The human adrenal gland is crucial for the synthesis of steroid hormones (glucocorticoids, mineralocorticoids, and androgens) and amino acid-derived hormones (epinephrine and norepinephrine). All steps in the adrenocortical steroidogenesis pathway are potential targets for chemical inhibition, including the adrenocorticotropic hormone receptor, steroidogenic acute regulatory protein, mitochondrial cytochrome P450 (CYP) enzymes (CYP11A1, CYP17, CYP21, CYP11B1, and CYP11B2), and 3-hydroxysteroid dehydrogenase D4,5 isomerase. EDCs either inhibit the …

Endocrine-Disrupting Chemicals In Metabolic Bone Diseases, Including Osteoporosis, Betül Gündüz, Eli̇f Kiliç Kan, Ayşegül Atmaca

Turkish Journal of Medical Sciences

Endocrine disruptors are chemical substances widely utilized across various industrial sectors. Due to their structural similarity to natural ligands, they bind to receptors and influence the endocrine system via agonist–antagonist mechanisms. Exposure occurs through the consumption of contaminated food and water, inhalation of polluted air and dust, and dermal contact. Owing to their dynamic remodeling capacity, bones represent potential targets for endocrine-disrupting chemicals. These chemicals can disrupt bone formation, skeletal development, hormonal regulation, and calcium metabolism. Sensitivity to endocrine-disrupting chemicals is greatest during the prenatal and early postnatal periods. This review summarizes the effects of endocrine-disrupting chemicals on bone tissue.

Targeting Pancreatic Cancer With Rapamycin-Loaded Gold Nanoparticles Conjugated To Egf Peptide: Studies On Cytotoxicity And Uptake Mechanisms Aided By Proteomic Analysis, Adeolu Oluremi

Theses and Dissertations

Pancreatic cancer remains one of the most lethal malignancies, with a five-year survival rate below 5%. While rapamycin (Rap) has demonstrated therapeutic potential, its clinical utility is hampered by systemic toxicity. To address this limitation, this study developed a targeted nanocarrier system using gold nanospheres (AuNPs) functionalized with the Epidermal Growth Factor Receptor (EGFR) peptide GE11 for the specific delivery of Rap to pancreatic cancer cells. It is to note that pancreatic cancer overexpresses EGFR. The AuNP–GE11–Rap conjugates were successfully synthesized and characterized using physico-chemical techniques, which confirmed peptide conjugation and drug loading. In vitro studies using PANC-1 cells demonstrated …

Effects Of Pamam Dendrimer Size On Antimicrobial Activity For Acne Treatment, Elise M. Inae

Honors Theses

This study investigated the antimicrobial activity of G1, G2, and G3-Hex-NH2 polyamidoamine (PAMAM) dendrimers with an emphasis on how dendrimer size influenced their efficacy against C. acnes and S. epidermidis. Dendrimers are nano-sized, radially symmetric polymers composed of highly branched units that extend out from a central core. Dendrimers are known to exhibit antimicrobial activity against Gram-negative bacteria by disrupting the lipid bilayer and causing membrane damage. This study explored their effect on a different group of microorganisms–Gram-positive skin flora. Kirby-Bauer disk diffusion tests were performed to evaluate minimum inhibitory concentrations for each dendrimer solution. All generations of PAMAM dendrimers …