Digital Commons Network^™

The Effects Of Ataxin-1 Overexpression In The Central Nervous System On Specific Behavioral And Physiological Characteristics Of Drosophila Melanogaster, Sydney Davis

Theses and Dissertations

Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by a CAG repeat expansion in the ataxin-1 gene, which results in an abnormally long polyglutamine tract. Similarly, overexpression of wildtype Ataxin-1 (wt-Atx-1) in Drosophila melanogaster leads to neurodegeneration, reduced lifespan, and impaired negative geotaxis. Observations include disruptions in sleep-wake cycles, increased oxidative stress biomarkers (like protein carbonyls), and dysregulation of developmental genes such as armadillo (arm) and nemo kinase (nmo). Additionally, elevated expression of SUMOylation-related genes (Aos-1, Uba2, and dSmt3 or dSumo) and increased SUMO protein levels indicate enhanced SUMOylation in the brain. Quantitative analysis of neuronal …

Work-Life Balance And The Impact Of Covid-19 On Faculty At Historically Black Community Colleges (Hbccs), Taneshia Turner Winston

Theses and Dissertations

This research study was conducted to determine how the COVID-19 pandemic affected the work-life balance of faculty at HBCCs based on their race, gender, age, marital status, and tenure status. The study employed a quantitative research design utilizing Exploratory Factor Analysis (EFA) to conduct time-based activities separately and group perception-based response variables into meaningful categories to uncover patterns. To analyze the differences in race, gender, age, marital status, and tenure status, Regression and Chi-square test analyses were used to evaluate the collected data. Regression analysis explored relationships between time spent on activities and perceptions of stress, productivity, and satisfaction. Chi-square …

Market Days For Older Adults: Addressing Healthy Aging Among A High-Risk Population At The Downtown Farmers’ Market, Allyson Brothers, India Luxton, Cheryl Noble, Sue Schneider, Alison O'Connor, Yuqin Jiao

Journal of Extension

Market Days for Older Adults is a Colorado State University Extension program that supplies low-income older adults with fresh produce purchased from market vendors at the local farmers’ market. Designed for low-income seniors, this program aims to enhance nutrition while building a sense of community and connection. Program evaluation data from the first four years of the program demonstrate evidence of program feasibility, including high levels of participant satisfaction and program utilization. We also assessed a set of healthy aging indicators (diet quality, social connection, functional health, and well-being) to drive future work. Implications for Extension professionals are discussed.

The Human Dimension Of "Home", Robert A. Destro

Catholic University Law Review

All societies provide a legal framework that protects the pivotal functions of home and family. None provide a clear legal definition of “home”. Nor, this article argues, can they. “Home” is a concept rooted in the lived experience of human persons. In this article, the second in a series, the author employs the “human dimension” [HDIM] concept, initially developed by the U.S. military and later adopted by the Organization for Security and Cooperation in Europe, as the lens through which one can examine the “human element” of human rights. The framework for this analysis is the “four clusters of value-types” …

The Effects Of Blood Flow Restriction And Body Weight Support Treadmill Walking On Electromyographic Activity In Lower Limb Muscles, Cyanea Davies

UNLV Theses, Dissertations, Professional Papers, and Capstones

Blood flow restriction (BFR) is an emerging rehabilitation modality shown to enhance muscle activation and elicit strength gains comparable to high-intensity training at lower loads (Cognetti et al.,2019). Body weight support (BWS) treadmill walking is another modality that has gained popularity due to the effect it has on lowering muscle activation with increasing support levels (Jensen et al.,2016). However, to date no research has looked at electromyographic (EMG) activity utilizing both modalities concurrently. This study investigated if stride frequency (SF) and muscle activity of the rectus femoris (RF), biceps femoris (BF), tibialis anterior (TA) and gastrocnemius (GA) would be influenced …

Healthy Bytes: Enhancing Health Literacy In Older Adults Through Technology Services, Gianna M. Susa

Master's Projects and Capstones

This quality improvement project aimed to enhance health literacy among senior residents through interactive technology workshops. Aim During a twelve-week period from January 22, 2025, to March 31, 2025, this project aimed to increase technology proficiency among senior residents from 0% to 75%. Methods A 5P Microsystem assessment and preliminary survey revealed residents' interest in technology workshops. Based on this feedback technology workshops were implemented once a week for a twelve-week period. Each session provided one on one support to help residents navigate online health portals, communicate with providers, and interpret health information. A SWOT analysis and Fishbone analysis were …

Hsp70 Chaperones, Ssa1 And Ssa2, Limit Poly(A) Binding Protein Aggregation, Hannah E. Buchholz, Sean A. Martin, Jane E. Dorweiler, Claire M. Radtke, Adam S. Knier, Natalia B. Beans, Anita L. Manogaran

Biological Sciences Faculty Research and Publications

Molecular chaperones play a central role in maintaining protein homeostasis. The highly conserved Hsp70 family of chaperones have major functions in folding of nascent peptides, protein refolding, and protein aggregate disassembly. In yeast, loss of two Hsp70 proteins, Ssa1 and Ssa2, is associated with decreased cellular growth and shortened lifespan. While heterologous or mutant temperature-sensitive proteins form anomalous large cytoplasmic inclusions in ssa1Δssa2Δ strains, it is unclear how endogenous wild-type proteins behave and are regulated in the presence of limiting Hsp70s. Using the wild-type yeast Poly A binding protein (Pab1), which is involved in mRNA binding and forms stress granules …

Holloway Competition Delivers Lessons That Outlast The Finals, Aaron Sanborn

UNH Today Archive

No abstract provided.

Behavior Analysts’ Training And Practices Regarding Cultural Diversity: A Replication And Extension, Tania M. Valdez-Nuguid

Theses & Dissertations

Culturally responsive care, which involves adapting assessment and treatment methods to reflect the culture of individuals served (Sue & Torino, 2005), is crucial for client success, especially for minoritized and marginalized groups. This study replicated and extended Beaulieu et al. (2019) by surveying behavior analysts on their training, perceived competence, and practices in culturally responsive care. We extended Beaulieu et al. (2019) by including open-ended questions regarding culturally responsive practices and barriers faced in delivering culturally responsive care and offering the survey in Spanish. Participants reported feeling skilled and comfortable providing culturally responsive care, with increased training across various modalities. …

The Impact Of The Mediterranean Diet On Depression: A Narrative Review, Emma Kate Schaaf

Honors Theses

Background. The Western diet has extensive negative ramifications on physical health and emotional well-being. The Mediterranean diet, widely regarded as one of the healthiest eating patterns in the world, may have the ability to improve psychological conditions. This study aims to examine existing research from randomized control trials (RCTs) on the association between depression prevalence and the Mediterranean diet.

Methods. The following review was conducted using PRISMA guidelines and the Google Scholar and PsycInfo databases. The criteria for inclusion were that studies: 1) were randomized control trials (RCTs) examining the Mediterranean diet; 2) included samples of adults (i.e., > 18 years …

The Well-Kept Wallet: Your Pathway To Financial Literacy, Lily M. Martin

Honors Theses

The Well-Kept Wallet: Your Pathway to Financial Literacy is an educational program created to engage young students ages kindergarten to college in age-appropriate financial literacy skills-building. In total, I gave 40 presentations to classrooms and community organizations, sharing essential financial literacy information. This paper discusses my reflections on giving these presentations, including what I learned throughout the process and the student’s reactions.

In addition, I completed a survey of University of Mississippi freshmen in an EDHE course to better understand the financial literacy of Ole Miss students in reference to nationwide results of a financial literacy survey conducted by the …

The Effects Of Environmental, Biological, And Social Factors On Telomere Length In Chestnut-Crowned Babblers, Carson L. Langston

Honors Thesis

Telomeres, repetitive nucleotide sequences at the ends of chromosomes, are vital in maintaining genomic integrity. Because degradation of these structures has been linked to oxidative stress, inflammation, and metabolic demands, they are also recognized as biomarkers for biological aging, lifespan, and physiological stress. This study investigates the ecological and physiological factors influencing telomere length changes in adult chestnut-crowned babblers (Pomatostomus ruficeps), a cooperatively breeding bird native to the arid and semi-arid zones of southeastern Australia. This species offers a valuable system for exploring how ecological pressures shape life history strategies due to the harsh environmental factors and social …

Integrating Positive Psychology And Spirituality To Foster Meaning And Well-Being In Older Adults, Crystal Morris

Adultspan Journal

This perspective article explores the integration of positive psychology interventions (PPIs) and spirituality in therapy to foster meaning and well-being in older adults. It highlights exercises such as the positive introduction, positive legacy, character strengths, mindfulness, mindful-based yoga, and a manifestation prayer journaling. The interventions presented are tools to support older adults that may experience depression, difficult life transitions, and the search for renewed meaning. Therapists who integrate PPIs and spirituality into therapy can promote a holistic, non-pathological approach to treatment.

Shopping Quest: Transforming The Shopping Experience By Creating A More Immersive And Enjoyable Experience, Nagasai Vardhan Rao Sarvepalli

Theses

In the post-pandemic era, this thesis looks into how gamification and augmented reality (AR) can get customers back into physical retail settings. Brick-and-mortar stores have found it difficult to stay relevant as consumer preferences have shifted toward online convenience. Shopping Quest attempts to make in-store grocery shopping an engaging experience. The project started with qualitative surveys using a human-centered design process to determine the main frustrations of shoppers, which were navigation and remembering what to buy. The final idea makes use of a wearable AR interface that directs users with a virtual rocket and promotes exploration with collectible digital petals. …

Cognitive Interviews With Emergency Physicians To Understand Disposition Decisions With People With Dementia With Borderline Cases, Anita N Chary, Annika R Bhananker, Rebecca Franks, Adrian Haimovich, Aanand D Naik, Maura Kennedy, Kei Ouchi

Faculty, Staff and Students Publications

People with dementia are often hospitalized from the emergency department (ED) for "borderline cases," where outpatient or inpatient management may be clinically reasonable. We sought to investigate how ED physicians make and communicate about decisions in borderline cases. Through cognitive interviews, we asked attending ED physicians from an academic hospital to share their approach to scenarios representing borderline cases with people with dementia and verbalize communication about ED disposition with patients and care partners. We deductively coded responses related to patient/care partner engagement and key features of communication and then elucidated themes related to content and phrasing of communication. Of …

Associations Of Muscular And Cardiovascular Fitness Variables With Cardiovascular Disease In Older Adult Athlete Populations, Lauren T. Zick

Honors Thesis

This data analysis examined associations between cardiovascular and muscular fitness indicators and the presence of cardiovascular disease (CVD) in older adult athletes. Using cross-sectional data from 1,110 participants aged 50 and older who completed the Sustained Athlete Fitness Exam (SAFE) at state-level Senior Games events, we evaluated both objective performance metrics and self-reported exercise behaviors. Cardiovascular measures included systolic blood pressure (SBP), waist circumference (WC), waist-to-hip ratio (WHR), and body mass index (BMI). Muscular fitness was assessed through grip strength, maximum walking speed, and chair stand time. CVD status was defined as the presence of two or more self-reported cardiovascular …

The Lived Experiences Of Registered Behavior Technicians Using Applied Behavior Analysis With Children With Autism Spectrum Disorder, Rebecca Rene Wyble

Walden Dissertations and Doctoral Studies

The prevalence of autism spectrum disorder (ASD) has increased dramatically over the past 20 years; the Centers for Disease Control describe ASD as an epidemic of need. Individuals with ASD need proper treatment and support services. One of the most significant needs is for applied behavior analysis (ABA), which is considered the most effective treatment for ASD, yet several barriers impede caregivers’ ability to access ABA, such as the shortage of ABA practitioners, including registered behavior technicians (RBTs). This qualitative phenomenological study explored the lived experiences of RBTs working with children with ASD in ABA settings in the United States. …

Overconfidence And Financial Risk Tolerance In Older Age, Colleen C Frank, Gary R Mottola, Meiru Chen, Lei Yu, Patricia A Boyle, Gregory R Samanez-Larkin, Kendra L Seaman

Faculty, Staff and Student Publications

Objectives: Excessive financial risk-taking in older age can have harmful consequences as opportunities to recover lost wealth are limited. Understanding financial risk-taking in older age is important for identifying vulnerabilities and developing interventions to empower aging investors to make wise financial choices. In this paper, we explore how overconfidence in financial knowledge affects financial risk-taking among older adults.

Methods: We examine this research question in older adults aged 58-101 (N = 1,242) using data from the Rush Memory and Aging Project (MAP).

Results: After controlling for demographics, overconfidence was associated with self-reported financial risk tolerance such that those who were …

Empathy And Psychological Outcomes In Informal Caregivers Of Community-Dwelling Older Adults: A Systematic Review And Meta-Analysis, Meng Huo, Thi Vu, Tomiko Yoneda, Jingkai Wei, Bruce Abbott, Joan K Monin

Faculty, Staff and Student Publications

Objectives: Scholars have increasingly recognized the crucial role that empathy plays as informal caregivers provide unpaid care to their older family and friends (i.e., care recipients). Yet, the existing literature exhibits substantial variability in study approaches and results, which limits the extent to which this literature can inform interventions intended to benefit informal caregivers. We sought to address this critical gap by synthesizing research that examined how caregivers' and care recipients' empathy were associated with caregivers' psychological health.

Methods: We conducted a literature search using PubMed, PsycInfo, CINAHL (Cumulative Index to Nursing and Allied Health Literature), EMBASE, and Scopus databases …

Fall Incidences, Risk Factors, And Health Effects Among Early- And Middle-Aged Elderly People In Rural Areas Of Border Provinces In Southern Thailand, Phnom Sukchan, Tapanan Prateepko, Arinda Ma-A-Lee, Kruawan Hounkong, Penporn Sujiwattanarat, Gornganok Piboonpol

Journal of Health Research

Background: Elderly individuals with physical and psychological challenges face a high risk of falls. This study aimed to assess the incidence, health effects of, and risk factors for falls among those aged 60-79 years old in Thailand's three southern border provinces.

Methods: A community cross-sectional study was conducted between October 2021 and September 2022. Questionnaires were administered though verbal face-to-face conversations. Descriptive statistics, the Chi-square test, Fisher’s exact test, and logistic regression were used.

Results: A total of 419 elderly participants were recruited, while 374 participated in the study. The incidence of falls was 37.4% with an average of 1.7 …

Nigeria's Retirement Pension System And Elderly Poverty, Tonyesima Furro

Journal of African Policy Studies

This study examines the nature of Nigeria's contributory retirement pension system. It shows that the government took monthly payroll deductions from the incomes of retirees and deposited in said retirement funds. Prior to retirement, retirees would receive a severance package of a lump-sum payment of a few months to a few years' earnings. They were assured that their regularly scheduled monthly disbursement would be remitted to their designated bank accounts. But due to the cumbersome bureaucratic procedures, many pension claimants were unsuccessful in receiving their benefits before death. The study reveals that the nation's pension administration system is characterized by …

Controlling Women’S Sexuality: The Rise Of Emotional Abuse Among Indian Husbands, Puranjay K. Vedi

Journal of International Women's Studies

In ancient Hindu literature, marriage is regarded as the most sacred institution while adultery—known as vyabhichāra (व्यभिचार) in Hindi—is considered one of the gravest sins. Ancient practices still have impact in 21st-century India, where internal household sanctions meant to ensure Indian wives’ chastity continue to be seen as sacred. This study describes six different types of Husband’s Controlling Behavior (HCB) that are used to preserve wives’ chastity. HCB can either take the form of emotional violence (accusing/suspecting a wife of being unfaithful) or physical violence (hitting or beating a wife out of a suspicion she is being unfaithful). This study …

Feminist Rehabilitation Counseling: Vocational Rehabilitation For Women With Disabilities In Global Contexts, Abigail O. Akande

Journal of International Women's Studies

People with disabilities are the most unemployed and underemployed minority group in the world, and women with disabilities (WWD) are further marginalized. Vocational rehabilitation (VR) is a human services discipline designed to support people with disabilities in obtaining and maintaining their employment goals. Competitive employment is a potential means for WWD to be empowered and to flourish by fostering a sense of economic security, encouraging community engagement, facilitating optimum levels of independence, contributing to the local economy, subverting the implications of poverty (e.g., limited healthcare, rehabilitation, and education access), and developing identities rooted in pride that often accompany the status …

Neighborhood Cohesion And Psychosocial Well-Being: Differences By Race/Ethnicity, Maverick E. Morales

Student Scholar Symposium Abstracts and Posters

Perceived neighborhood cohesion is related to numerous mental health benefits, yet some research suggests racial/ethnic disparities in access to neighborhood cohesion. Much of the existing research investigates only one outcome, limiting the ability to synthesize across findings. The strength of the current study is that it utilized an outcome-wide approach to investigate racial/ethnic differences in associations between perceived neighborhood cohesion and four psychosocial outcomes. Using data from the Health and Retirement Study, we tested the hypotheses that (1) higher perceived neighborhood cohesion would relate to higher life satisfaction and lower anxiety, loneliness, and perceived stress, and that (2) non-Hispanic White …

Impact Of Visual And Auditory Distractors On Spot-The-Difference Task Performance, Julia N. Gross, Alexia Urban, Julius Kloepfer, Hannah Eversole

Aurora

In everyday life, individuals are faced with tasks that require sustained, visual attention. However, distractions are also a part of everyday life, and with the increase in technology use came an increase in distractions that may affect concentration and performance on these visual tasks. Previous research has examined how task-unrelated visual and auditory stimuli, presented at different intensities, impact functions of learning and memory. However, it has yet to determine their impact on ongoing, attention-demanding, visual tasks. The present study used a 2x2 between-subjects design to test the impact of both visual and auditory distractors, presented at either a high …

Educating The Educators: Increased Sexuality Training For Counselor Educators, Joshua C. Taylor

Journal of Counseling Sexology & Sexual Wellness: Research, Practice, and Education

A robust body of literature has identified the need for counselors-in-training (CITs) to receive additional training in sexuality counseling. Growing efforts to identify efficacious training strategies have also been well-documented in the literature. These suggested updates have implicitly increased the counselor educator's role in delivering strategies to promote sexual counseling competence for CITs. Unfortunately, there is a dearth of literature regarding the adequate preparation of counselor educators in providing sexuality education. This article will underscore the counselor educator’s role in facilitating competence in sexuality counseling for CITs and provide a model for infusing sexuality counseling into doctoral curriculum.

Implementation Of An Evidence-Based Hearing Education Project For Patients And Their Care Partners, Jennifer Mahoney

Doctoral Projects

Hearing loss is a significant communication issue that impacts relationships, safety, and mental and physical health. There is an increased risk of dementia as well as increased mortality associated with untreated hearing loss. Hearing aids are one of the main treatments for hearing loss, but they are frequently not used. Cognitive impairment, osteoarthritis of the hands, cost and complexity are some of the reasons that hearing aids do not get utilized. But research has shown that involving family members and care partners in trainings on how to use hearing aids may increase use of them. The goal of this project …

A Quality Improvement Project On Implementing A Nurse-Driven Foley Catheter Removal Protocol Using Modified Houdini Criteria For Oncology Patients To Reduce The Catheter-Associated Urinary Tract Infection (Cauti) And Catheter Days In The Intensive Care Unit (Icu), Rittu K. Justin

Doctor of Nursing Practice Final Project Abstract

Purpose: This scholarly project aimed to develop modified criteria for oncology patients regarding Foley catheter removal guidance and implement a nurse initiative in the ICU to reduce CAUTI and catheter days.

Background: CAUTIs are considered preventable nosocomial infections; hence, a nurse-driven Foley catheter removal protocol has become an essential strategy in healthcare to reduce CAUTIs. The project was implemented in a 43-bed ICU in an academic hospital at the Texas Medical Center. The 12-week pilot project included adult patients with a primary diagnosis of cancer.

Methodology: A quantitative design with a PDSA framework was employed. The institutional infection control trend …

Cumulative Lifespan Stress And Inflammation Are Associated With Black-White Racial Disparities In Mortality Among Americans, Isaiah Spears

Arts & Sciences Graduate Student Theses and Dissertations

Black Americans disproportionately experience higher rates of health challenges and mortality compared to White Americans, yet the mechanisms underlying these disparities remain inadequately understood. Prominent theoretical models highlight stress and resulting allostatic load as putative mechanisms through which these Black-White racial disparities emerge; however, empirical data supporting such models with regard to mortality remains sparse. The current study examined the potential role of cumulative stress exposure across the life span and elevated levels of C-Reactive Protein, a biomarker of inflammation, in contributing to the longstanding increased mortality risk among Black relative to White Americans. Data were drawn from the Saint …

What Are The Effects Of Time-Restricted Eating Upon Metabolic Health Outcomes In Individuals With Metabolic Syndrome: A Scoping Review, Rory J Heath, Jessie Welbourne, Daniel Martin

Peninsula Medical School

The primary objective of this scoping review (ScR) was to assess the breadth and type of evidence related to time-restricted eating (TRE) as an intervention to modify metabolic health outcomes in individuals with diagnosed metabolic syndrome (MetS), a major health challenge due to increasing prevalence and association with other chronic diseases. MetS comprises three or more of hypertension, hypercholesterolaemia, dyslipidaemia, dysregulated glucose homeostasis, and abdominal obesity. TRE, also known as time-restricted feeding (TRF), restricts food intake to specific time windows within a day, for example, a 10-h eating period between 10:00 and 20:00. Via multiple mechanisms, TRE interventions may provide …