Digital Commons Network^™

Examining The Relationship Between School Location, Neighborhood Resources And Advancement Courses Offerings, Eudarius Jones

Electronic Theses and Dissertations Archive

This study addresses a critical gap in educational equity research by examining how neighborhood-level factors intersect to shape access to rigorous academic programming, a key gateway to postsecondary success. Integrating geospatial visualization and hierarchical linear modeling within a critical geography framework, the study investigates how structural inequalities—rooted in race, poverty, and place—influence advanced course-taking opportunities across the Memphis metropolitan region. Data sources included the U.S. Department of Education’s Common Core of Data (CCD) for district-level enrollment and school type, the U.S. Census and American Community Survey (ACS) for demographic and socioeconomic indicators, and the National Center for Charitable Statistics (NCCS) …

Hif-2-Dependent Regulation Of Pthrp And Paraneoplastic Hypercalcemia In Aggressive Clear-Cell Renal Cell Carcinoma, Arijit Mal, Bingqing Xie, Zane Gray, Charlotte Small, Susmita G Ramanand, Yunpeng Gao, Vanina Toffessi Tcheuyap, Sashi Debnath, Alana Christie, Jeffrey Miyata, Brooklyn Jackson, Hua Zhong, Boning Gao, Jay Lohrey, Naim M Maalouf, Sangeetha M Reddy, John D Minna, Ivan Pedrosa, Xiankai Sun, Ram S Mani, Payal Kapur, James Brugarolas

Faculty, Staff and Student Publications

Renal cell carcinoma (RCC) patients with hypercalcemia (HC) have worse outcomes. HC often involves PTHrP, and the role of HIF-2 is incompletely understood. Leveraging RCC tumorgraft (TG) models of HC, which were characterized by tumor cell autonomous inflamatory/immune signatures, we show that HIF-2 inhibition with PT2399 frequently normalized calcium, downregulated circulating PTHrP and reduced HIF-2 binding to the PTHLH (PTHrP) promoter. Likely contributing to the selective induction of PTHrP in a subset of HIF-2-dependent tumors, the PTHLH locus was generally more accessible in TG(HC). However, PTHLH chromatin accessibility was grossly unaffected by PT2399, unlike elsewhere (including EPO locus in a …

Multi-Omic Profiling Provides Insights Into The Heterogeneity, Microenvironmental Features, And Biomarker Landscape Of Small-Cell Lung Cancer, Mingchao Xie, Miljenka Vuko, Shashank Saran, Siyu Liu, Andrew G Chambers, Hana Baakza, Helen K Angell, Felicia Ng, Carl M Gay, Robert J Cardnell, Felix J Segerer, Alma Andoni, Jaime Rodriguez-Canales, Paul M Waring, Markus Schick, J Carl Barrett, Lauren A Byers, Giulia Fabbri

Faculty, Staff and Student Publications

Background: Greater understanding of differential therapeutic sensitivity, specifically to immunotherapy, in small-cell lung cancer (SCLC) is required.

Methods: We explored SCLC heterogeneity through integrated molecular characterization of tumor tissue samples from 159 treatment-naive patients, utilizing genetic, epigenetic, transcriptional, and proteomic profiling, immunohistochemistry staining for multiple biologically relevant markers including transcriptional subtype-defining proteins, and spatial immune profiling using multiplex immunofluorescence.

Results: Multi-omics analysis confirmed high heterogeneity across/within neuroendocrine and non-neuroendocrine subtypes. Methylomics analysis identified four methylome clusters that may enhance subtype prediction, prognosis, and longitudinal monitoring of subtype evolution. Immunohistochemistry analysis showed high MHC-I expression in non-neuroendocrine subtypes, which have greatest …

Inhibition Of Clostridioides Difficile-Specific Dna Adenine Methyltransferase Cama By Analogs Of S‑Adenosyl‑L‑Methionine, Jujun Zhou, Youchao Deng, Dan Yu, Taraneh Hajian, Masoud Vedadi, Xing Zhang, Robert M Blumenthal, Rong Huang, Xiaodong Cheng

Faculty, Staff and Student Publications

Epigenetically targeted therapies, especially those inhibiting S-adenosyl-l-methionine (SAM)-dependent methylations of DNA, mRNA, and histones, have advanced rapidly in cancer treatment. However, these therapies remain underexplored for antibiotic development, despite the growing threat of antimicrobial resistance. Here, we screened a focused library of SAM analogs against the DNA adenine methyltransferase CamA specific to the enteric pathogen Clostridioides difficile. At the same time, we examined six other adenine methyltransferases, including two bacterial DNA methyltransferases and four human RNA methyltransferases having distinct RNA substrates. Compound 113 selectively inhibited CamA (IC50 = 0.15 μM). In addition, compound 67 inhibited Caulobacter crescentus CcrM …

Readability Analysis Of Aaos And Assh Shoulder And Elbow Patient Education Online Content: A 9-Year Follow-Up Study, Connor Parry, Teresa Veselack, Matthew Doscher, Bryan G. Beutel

Student Publications

Given the progressive spread of medical misinformation, access to understandable educational content from trusted sources has become increasingly more crucial for patients. Online patient education materials, particularly from specialty organizations, have been criticized for being too complex for the average reader. It is advised that this information be at or below the 6^th-grade reading level. This study is a 9-year follow-up to an analysis conducted in 2013 which evaluated the overall readability of educational articles from the American Academy of Orthopaedic Surgeons (AAOS) and American Society for Surgery of the Hand (ASSH) websites related to shoulder and elbow …

Netherton Syndrome: A Systematic Review Of The Challenges Of Diagnosis And Treatment, Maximus S. Reese, Ryan Nguyen, Noor Chughtai, Philip J. Haynos, Salma Alkhatib, Shantanu Amin, Ethan Speer, Jared Nichols

Student Publications

Netherton syndrome is an autosomal recessive genodermatosis caused by biallelic mutations in the SPINK5 gene, a gene that codes for lymphoepithelial Kazal-type-related inhibitor 1 (LEKT1) protein. This disorder is characterized by erythroderma, ichthyosis, hair shaft abnormalities, and immune dysregulation. While there is increasing research and recognition of Netherton syndrome, much remains unknown, with limited knowledge of the history, manifestations, and responses to therapies. The purpose of this study was to review case reports of Netherton’s to draw conclusions from patient demographics, symptoms, treatment, and outcomes. A systematic review of 30 case reports and clinical studies on Netherton syndrome was conducted, …

The Legal Position Of The Religious Communities In The Republic Of Macedonia, Jovan Jonovski

Occasional Papers on Religion in Eastern Europe

The territory of the modern Republic of Macedonia (official name as of recently is Republic of North Macedonia) has historically been exposed to Judaism, Eastern and Western Christianity, Islam, and later to Protestantism. In the People’s /Socialist Republic of Macedonia, the religious communities were kept out of public life and suppressed. The government favored the Macedonian Orthodox Church for strengthening the Macedonian national consciousness. The Republic of Macedonia is a self-declared secular multi-confessional state. The article covers the history of the religious landscape as well as the legal framework and practices of the state toward the Churches, faith communities, and …

Orthodoxy, Culture And Language: Alaska In Russia’S Religious Diplomacy Of The 21st Century, Oleksandr Lukyanenko

Occasional Papers on Religion in Eastern Europe

The article is devoted to the analysis of the religious factor of the Russian foreign diplomacy in the light of Vladimir Putin’s high-profile visit to Alaska n August 15, 2025. The paper studies a special place of Alaska in the historical imagination of Russian political and church discourse. The status of this particular territory in Russian state worldview – the former “Russian America” – is indicative: it refers to the idea of an unfinished imperial legacy. The research doesn’t touch a main event that included a meeting with US President Donald Trump but an off-schedule meeting with Archbishop Alexei (Trader) …

“Mysterium Tremendum Et Fascinans”: Melian’S And Lúthien’S Numinosity, Alexandra (Oleksandra) Filonenko

Mythopoeic Society Seminar Proceedings

At the heart of all the positive changes in Middle-earth, and at the starting point for undoing the great evil wrought by male characters (divine or otherwise), are two female characters: Melian the Maia and her daughter Lúthien. They form a kind of mythological complex of mother and daughter goddesses, similar to that of Demeter and Persephone. Melian, as a static, maternal figure, forms a sacred centre of Beleriand to which all in need of protection gravitate, while Lúthien, representing a dynamic principle, can be considered the greatest hero of Tolkien’s Legendarium, performing feats unmatched by any male character. Yet …

Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions, Anna Smol

Mythopoeic Society Seminar Proceedings

"Grendel's Mother Talks Back: Contemporary Women's Mythopoeic Revisions" examines how twenty-first-century feminist adaptations and translations examine the significance and point of view of Grendel's Mother, a character from the Old English poem Beowulf. In contrast to past views of Beowulf, especially in J.R.R. Tolkien's influential essay on the poem, these women writers and scholars argue for the central role of Grendel's Mother and give voice to her story. The paper discusses the main features of these adaptations, covering topics of narrative voice, borderlands, violence, and motherhood, and generally questions the concept of monstrosity as applied to Grendel's Mother. The paper …

Sex, The Body, And Learning Gender: Demons In The World Of The Five Gods, Erin E. Mcbrien

Mythopoeic Society Seminar Proceedings

“Sex, the Body, and Learning Gender” analyzes the relationship between the physical body, sexual orientation, and gender as characterized within Lois McMaster Bujold’s World of the Five Gods series, with a particular emphasis on her Penric and Desdemona novellas. Using the framework of Bussey and Bandura’s social learning theory, and a close reading of Bujold’s text, this paper explores how the demonic characters within this series are an example of gender as a learned concept rather than a biological imperative. This is further developed by examining how the demonic characters both imprint on and contrast against the more societally-bound sorcerers …

Belief After The Death Of King Arthur: Lev Grossman’S Postsecular Portrayal Of Nimue In The Bright Sword, Liz Busby

Mythopoeic Society Seminar Proceedings

This paper explores Lev Grossman’s 2024 novel The Bright Sword as a postsecular retelling of the Arthurian legend, focusing on the character of Nimue. Unlike previous modern portrayals that align Nimue with pagan traditions in opposition to Christianity, Grossman presents her as both a practitioner of magic and a sincere Christian believer. Through this duality, Nimue embodies the tensions and contradictions of faith in a postmodern age, where belief persists amid doubt, historical trauma, and religious pluralism. Drawing on postsecular theory, the paper situates Grossman’s work within a broader literary tradition that includes Marion Zimmer Bradley’s The Mists of Avalon …

Still Perilous, Still Fair: Perspectives On The Legacy, Or How (Not)Eowyn And (Not)Galadriel Made The Magic Work, Janet Croft, Leslie Donovan

Mythopoeic Society Seminar Proceedings

An informal and wide-ranging conversation between the co-editors of Perilous and Fair: Women in the Works and Life of J.R.R. Tolkien will cover the genesis and development of the project and the pitfalls and traps for the unwary we encountered along the way. We'll talk about the technicalities of our process as editors -- from developing the call for papers through choosing the cover art. And we'll assess the influence the collection has had on subsequent scholarship, and the continuing significance of some of the work included.

More Perilous And Fair, Cami Agan, Clare Moore, Robin A. Reid Dr.

Mythopoeic Society Seminar Proceedings

An overview of the conference's theme and speakers.

Taking A Trip Into Nature’S Medicine Cabinet: A Country Comparison Of Efforts To Reschedule Psilocybin And Mdma For Therapeutic Use, Ariyah Jones

Georgia Journal of International & Comparative Law

No abstract provided.

Arbitrating Business And Human Rights Disputes In Latin America, Gloria Correa

Georgia Journal of International & Comparative Law

No abstract provided.

The Internet Of Hate: Comparing The Nature, Harms, And Regulatory Challenges Of Online And Offline Hate Speech, Alexander Brown

Georgia Journal of International & Comparative Law

No abstract provided.

Engaging Ukrainian Tf-Cbt Therapists In A Practice Skills Course To Support Their Wellbeing, Elisabeth Pollio, Esther Deblinger, Beth Cooper, Maike Garbade, Julie P Harrison, Elisa Pfeiffer

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Background: Burnout and secondary traumatic stress (STS) are common among therapists working with trauma-exposed clients, which can negatively impact them professionally and personally. The shared trauma of war exposure may put therapists at greater risk. To help support their wellbeing, an eight-session course was offered to Ukrainian therapists following training in Trauma-Focused Cognitive Behavioral Therapy (TF-CBT). This course involves therapists personally utilizing the PRACTICE skills taught to clients in TF-CBT for professional and personal benefit.

Objective: The objective was to gather preliminary evidence on the potential impact of implementing the course with Ukrainian therapists providing TF-CBT during a period of …

“She’S A Good Different. She’S Revolutionary”: How Fifth-Grade Readers Interpret Aspects Of Diversity In Literature, Margaret Barr

Reading Horizons: A Journal of Literacy and Language Arts

Although diversity, equity, and inclusion have been a significant focus of research in children’s literature, many studies fail to consider the reader’s perspective and instead rely on text analyses. In the present study, the author employed focus groups to examine fifth-grade readers’ insights as they interpreted, related to, and engaged with the presence of diversity in texts. Findings indicate that readers interpreted diversity by envisioning the larger picture, recognizing the importance of others’ differences, and connecting through emotions. Thus, this study suggests that it is necessary for teachers to understand that students recognize and appreciate individual differences, to select texts …

Pre-Service Teacher Preparation In Over/Underrepresentation Of Students From Culturally Linguistically Diverse Backgrounds In Special Education: A Systematic Review Of State-Level Policies, Enso Yushu Liu

Student Scholarship

No abstract provided.

Using Insecticidal Compounds To Elucidate The Potential Role Of Neurotransmitters In Lepidoptera Pupal Ecdysis, Niranjana Krishnan, Cassandra Gorman, Jillian Stewart, Steven Bradbury, Russell Jurenka

Biological Sciences Faculty Research & Creative Works

Previously, we reported final-instar lepidopteran larvae exposed to low doses of imidacloprid, clothianidin, and thiamethoxam had arrest in pupal ecdysis, which is a novel adverse outcome for neonicotinoid insecticides. Since neonicotinoids disrupt acetylcholine signaling, we hypothesized that the excitatory neurotransmitter acetylcholine plays a critical role in regulation of pupal ecdysis, likely by modulating the release of peptides from crustacean cardioactive peptide (CCAP) neurons. In this paper, using two lepidopteran species, we undertook studies with five additional nicotinic acetylcholine receptor (nAChR) agonists and three muscarinic acetylcholine receptor (mAChR) agonists to hypothesize the putative nAChR subunits that mediate pupal ecdysis. We also …

Bard Observer Vol. 24, No. 3 (December 2025), Bard College

Bard Observer, 2020 - 2029

No abstract provided.

Aged 539 Graduate Internship Report - Mt. Whitney High School, Tule Marie Cardoza

Agricultural Education: Graduate Internship Reports

This project reviewed a high school agricultural education program with an emphasis on agricultural mechanics. Program strengths and needs were identified through curriculum and resource evaluation. Based on the findings, a budget was developed to support equipment, materials, and instructional improvements for the ag mechanics program.

Reducing Opioid Overdose Harm Through Narcan Access And Education, Shane Alexander Role Alihan, Jared Timothy Chua, Siwapond (Taylor) Yuen, Matthew Reynon

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

Background: The overuse of opioids has led to an epidemic that affects the health of young adults in Sacramento, CA. Social and economic factors have influenced the use of opioids which has led those individuals to acquire an addiction and dependency to such drugs. This age group is typically engaged in college and career-minded endeavors. Thus, the impact on this age group is substantial, requiring impactful interventions.

Aim: The purpose of this intervention is to provide a foundation for educating those affected by opioid overdose. This strategic goal is to equip students at the University of the Pacific’s Entry-Level …

Where Do I Go Next With This Writer? Preservice Teachers’ Responses At The Start And End Of A Writing Methods Course, Nicole M. Martin, Lisa K. Hawkins, Diane M. Bottomley, Brendan Shanahan, Jennifer Cooper Mrs.

Reading Horizons: A Journal of Literacy and Language Arts

This mixed-methods study sought to extend what is known about preservice teachers’ (PSTs’) preparation for teaching writing by examining their responding to individual children’s narrative, informative, and persuasive writing at the start and end of a writing methods course. Participants were 115 elementary PSTs. Their selections of teaching foci and instructional strategies on a beginningand end-of-semester course task were examined. Overall, PSTs showcased differences in their selections at the two time points, displaying a lessened focus on local features (e.g., spelling, punctuation) and reliance on laypeople’s helping practices (e.g., telling, correcting writing) and a greater focus on global features (e.g., …

Teachers’ Perspectives On Text Selection In A Time Of Book Bans And Censorship, Natalie Sue Svrcek, Kathleen Colantonio-Yurko, Henry "Cody" Miller

Reading Horizons: A Journal of Literacy and Language Arts

The last 4 years of headlines describing the various book bans and curricular gag orders happening in the United States serve as an important context for P–12 teachers’ daily work. This article describes the findings from a qualitative survey that sought to understand what influences P–12 teachers’ text selection for teaching and for inclusion in their classroom library in the aforementioned context. Teachers reported stakeholders who held decision-making power as well as which stakeholders were influential in their text selection. Three overarching themes emerged from teachers’ most influential factors in their text selection: social and communal influences, literary content and …

Beyond The Red Pen: Investigating The Formation Of Reader And Writer Identity Development In Preservice Teachers, Sarah Rutt Williams, Pengtong Qu, Lydia Denning

Reading Horizons: A Journal of Literacy and Language Arts

The influence of identifying as a reader and writer in being a literacy teacher has been emphasized in the literature (Graves, 1983). However, few studies have explored how teacher education programs develop these identities in preservice teachers (PSTs). Grounded in Demerath’s (2006) epistemological identity theory, this study explored the fluid process of teacher identity formation, focusing on nurturing PSTs’ identities as readers and writers. The study took place over one semester in an English Education course. The researchers analyzed three PST participants’ weekly reflections about their beliefs regarding teaching and learning literacy. These statements revolved around topics that aligned with …

2025 Fall Commencement Program, The University Of West Alabama

Commencement Programs

No abstract provided.

Aged 539 Graduate Internship Report – San Marcos High School, Stephanie Navarrete

Agricultural Education: Graduate Internship Reports

This project report includes documentation required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The supporting documents include information to prove that San Marcos High School is meeting the requirements. This document also provides an overview of San Marcos High School agriculture program.

Implementation Of An Institution-Specific Checklist To Improve Compliance With Discharge Round Completion In A Neonatal Intensive Care Unit, Lee A. Lawson

Student Scholarly Projects

Practice Problem: Effective discharge planning for premature infants in the NICU requires collaboration and coordination among multidisciplinary interprofessional (IP) teams. Ineffective communication during care transitions is a well-documented contributor to adverse patient outcomes, including prolonged hospitalization.

PICOT: For multidisciplinary, interprofessional teams in the NICU (P), how does the introduction of an institution-specific discharge checklist (I), compared to the current unit discharge process (C), affect multidisciplinary, interprofessional team compliance with completing weekly discharge rounds (O) within 6 weeks (T)?

Evidence: The reviewed literature supported the use of a discharge checklist tool to facilitate effective team communication and care coordination with parents …