Digital Commons Network^™

Novel Physical And Biological Applications Of Carbon Ion Radiotherapy, Danushka Seneviratne, Prapannajeet Biswal, Sunil Krishnan

The Brown Foundation: Institute of Molecular Medicine

Carbon ion radiation therapy (CIRT) is a high-LET radiotherapy, which distinguishes itself from traditional low-LET radiation, such as photons and protons, through its unique physical aspects, biological attributes, and the dramatically increased damage it causes within cellular DNA. Given its distinctive characteristics, it is expected to improve the therapeutic ratio of radiation treatments and enhance treatment outcomes in traditionally radiation-resistant tumor histologies. Despite these unique properties, much remains to be understood regarding the clinical use of CIRT before its full potential can be realized. In this review, we summarize the distinct advantages of CIRT with regard to its physical and …

Mental Health And Beliefs About Abortion Access Following Changes To Reproductive Healthcare Laws In 2022: Findings From Oklahoma, Munjireen Sifat, Laili K. Boozary, Tina N. Le, Julia Mcquoid, Brittany Zaring-Hinkle, Sarah Tonkin, Lizbeth Benson, Bingjing Mao, Motolani Ogunsanya, Ruosi Shao, Amy M. Cohn, Allyson Shortle, Darla E. Kendzor

Department of Medical Oncology Faculty Papers

INTRODUCTION: A secondary analysis of cross-sectional survey data was conducted to characterize beliefs about abortion access in Oklahoma, measure stress associated with the overturn of Roe vs. Wade (2022), and evaluate the potential relationship between post-Roe stress (PR stress) and mental health.

METHODS: From August through September 2022, adult Oklahomans (N = 1793) were surveyed about their sociodemographic characteristics, beliefs about abortion access, frequency of past-month stress related to the overturn of Roe vs. Wade, and mental health. Beliefs about abortion access were characterized overall and within sociodemographic groups. The relationship between PR stress and mental health was evaluated, and …

Knowledge Of Cpr And Code Status Discussions In Traumatically Injured Older Adults: Does Health Literacy Matter, Mokunfayo O Fajemisin, Ashna S Karpe, Stephanie Martinez Ugarte, Gabrielle E Hatton, Krislynn Mueck, Lillian S Kao, Martin L Blakely, Gina H Khraish, Aanand Naik, Shreyans Sanghvi, Jessica L Lee, Thaddeus J Puzio

Faculty, Staff and Student Publications

Code Status Discussions (CSDs), CPR understanding, and health literacy is understudied in traumatically injured older adults. We hypothesized that traumatically injured older adults and their families would have limited understanding of CPR and code status, and that lower health literacy would be associated with reduced advance care planning knowledge. We surveyed injured adults ≥65 or their surrogates to assess baseline code status, health literacy, and CPR discussions. Univariate and multivariable analyses were conducted. Among 201 respondents 55% had low health literacy. Only 38% had discussions about CPR, and 21% were asked about code status during admission. Surrogates similarly overestimated CPR …

My Research Journey Into Family Domestic Work: Methodological Reflections Of Conducting Research With Sister-Maids And Sister-Madams In Limpopo, Percyval Bayane

The Qualitative Report

Research has been conducted on domestic work in South Africa with studies focusing on domestic workers’ conditions during Apartheid and examining the little to no changes post-Apartheid. Domestic work in post-Apartheid South Africa involves the hiring of family and friends as domestic workers, and this is an under-researched area. As a young black man researching family domestic work, I was confronted with methodological challenges relating to negotiating access and conducting interviews with older black women hiring relatives and those working for family members as domestic workers. This reflexive paper reflects on my personal journey and experiences of conducting qualitative research …

Fostering Multicultural Education And Building Community Resilience In Post-Pandemic Schools In Southwest England, Suparna Bagchi

School of Law, Humanities and Social Sciences

This article explores the complexities of practicing meaningful multicultural education in varied sociocultural landscapes, including areas with limited ethnic diversity. Highlighting how the COVID-19 pandemic revealed deep-rooted structural inequalities, the article emphasises the need for education systems to address the specific realities of Black, Asian, and Minority Ethnic (BAME) communities. This is because the study findings reveal a lack of curricular representation of BAME communities, time constraints that prevent teachers from incorporating multicultural education into their daily routines, limited understanding around multicultural education among teachers, and a need for recruiting and retaining teachers from diverse communities. This article revisits existing …

Invasive Candidiasis In Critically Ill Patients: Fundamental Concepts And Future Directions, María Alejandra Pérez, Wesley J Hoffmann, J Christian Pérez, Max W Adelman

Faculty, Staff and Student Publications

Topic importance: Invasive candidiasis (IC) is a common complication in patients in ICUs. IC can be divided into bloodstream infections (candidemia) and deep-seated infections. Candida infections are associated with high mortality and longer hospital stays. Moreover, the emergence of Candida auris and other species prone to cause ICU outbreaks highlights the importance of this pathogen.

Review findings: Candidemia represents about 20% of bloodstream infections in ICU patients, whereas intraabdominal candidiasis, the most common form of deep-seated infection, predominantly affects surgical ICU patients. Regarding species distribution, Candida albicans is the most common species; however, non-albicans species have become more prevalent in …

Psychological Resilience As A Predictor Of Occupational Stress Among Teaching Staff In Course X, Indah Kusuma Wardani, Fajaria Nurcandra, Dr. Dyah Utari, Afif Amir Amrullah

Jurnal Epidemiologi Kesehatan Indonesia

Workplace stress is a common condition that may be triggered by the demands of professional involvement. Psychological resilience functions as a protective factor that enables individuals to maintain their level of work engagement despite experiencing job-related stress arising from work–life imbalance. This study aimed to examine the relationship between psychological resilience and occupational stress among teaching staff at Course X. The research employed a quantitative approach with a cross-sectional design, utilizing chi-square testing and Cox regression analysis, with a total sample of 98 participants. Data collection was conducted from April to June 2024. The instruments used included the Workplace Stress …

Composition Of Essential Oil From Dried Basil (Ocimum Basilicum L.), Ajargul Abdiganievna Mambetsheripova, Shakhnoza Abduvaxitovna Sultanova, Jasur Esirgapovich Safarov

Technical science and innovation

Ushbu ishda maydalangan rayhon (Ocimum basilicum L.) o‘simliklaridan olingan efir moylarini (EM) ajratish va tahlil qilishga oid metodologik yondashuv bayon etilgan. Rayhon efir moyi klassik Klevenger apparati yordamida uch soat davomida gidrodistillyatsiya usulida ajratib olindi. Olingan distillyatlar n-geksan bilan ishlov berildi, so‘ngra qoldiq namlikni yo‘qotish maqsadida suvsiz natriy sulfat yordamida degidratatsiya qilindi. Ushbu sharoitda efir moyining chiqishi 0,74–0,81 % oralig‘ida bo‘ldi. Izolyatsiya qilingan moylar rang jihatdan och sariq, harakatchan suyuqliklar bo‘lib, rayhonga xos o‘ziga xos aromatik hidga ega ekanligi aniqlandi. Kimyoviy komponentlarni aniqlash uchun efir moyining sifat va miqdoriy tarkibi gaz xromatografiya-mass-spektrometriyasi (GXM-S) usulida o‘rganildi. Tahlillar Agilent 5975C inert MSD/7890A …

Examining Herd Behavior In The Saudi Stock Market, Salah Ahmed Oraby

Journal of King Abdulaziz University: Economics and Administration

The study aims to determine whether market conditions motivate individual investors to engage in herd behavior from 2013 to 2023 for the Saudi stock capital as an emerging market. To achieve this goal, the study used the cross-sectional absolute mean–median difference as the proxy for herd behavior and as the dependent variable, market returns as the independent variable. In addition, the study used descriptive statistics to describe the study variables and the least square regression models to test the study's hypotheses. The overall results for the entire study period found that individual investors exercised irrational herd behavior. However, the yearly …

Evaluating The Impact Of A Language Translation Standard Operating Procedure For The Multi-Professional Team Working In A Maternity Care Service, Fiona Howard

South West Clinical School Journal

No abstract provided.

Neuroprotection Of Patients After An Out-Of-Hospital Cardiac Arrest: A Clinical Audit Project Proposal, Rebecca Russell

South West Clinical School Journal

No abstract provided.

Developing And Implementing A Support Intervention For Staff Delivering Enhanced Care In An Acute Older People’S Ward, Rey Pacanza

South West Clinical School Journal

No abstract provided.

Exercise Groups In Stroke And Neurorehabilitation: A Service Evaluation, Anna Lloyd, Angie Logan

South West Clinical School Journal

No abstract provided.

Identifying Opportunities And Challenges Staff Experience Assessing And Monitoring Physical Health In Early Intervention In Psychosis Services, Sophie Power

South West Clinical School Journal

No abstract provided.

Archaeology Of Roads: A Case Study Of The 18th-Century Surosowan–Tasikardi Old Road In Banten Lama As The Sultan’S Road, Destian Pandu Dwicahyo Santoso Putro, Ghilman Assilmi

Paradigma: Jurnal Kajian Budaya

Archaeological studies on roads in Indonesia remain relatively limited, although international research indicates that roads are not merely transportation infrastructure, but also embody social, political, and symbolic dimensions. A significant example is the ancient road in Banten Lama, which connects the Surosowan Palace with the artificial lake of Tasikardi. This study aims to present archaeological data and identify the distinctive characteristics of royal roads compared to common roads, applying a landscape archaeology approach within a post-processual paradigm. The research stages include data collection, processing, and interpretation through qualitative methods, encompassing literature review and field observation. The analysis shows that the …

Lahirnya Tensi Metafisik Di Urat-Leher Projek-Projek Interpretasi Konstruktif, Herman Bakir, Mukhtasar Syamsuddin

Jurnal Hukum & Pembangunan

This project is a legal hermeneutics. The aim is to elaborate the paradigm of the law as integrity theory, Ronald Dworkin’s work, which has received recognition as one of the most influential philosophical systems in the world of law throughout the last century. The issues discussed are divided into three subjects: (1) the interpretation role in legitimizing “law” as a corpus that has a “soul”; (2) a concept of interpretation from the womb of the law as integrity theory; (3) the dual capacity of “constructive interpretation” in [a] “returning” law to its roots; and [b] housing “morals” within the body …

Exploring Political Neutrality And Disengagement: The Experiences Of Jehovah’S Witnesses Students In Educational Settings, Kurt Zeus L. Dizon

Social Sciences and Development Review

Schools are tasked with instilling civic and social responsibility values, and such means are achieved through political activities. However, for Jehovah’s Witness (JW) students, participation in such activities can conflict with their religious convictions, presenting a unique challenge as they navigate educational expectations while striving to uphold their beliefs. Hence, this study explores the experiences of JW students regarding their political neutrality and disengagement in educational settings. Utilizing qualitative interviews and document analysis, the research identifies the political activities and challenges JW students face and the coping mechanisms they employ to reconcile their religious commitments with political expectations. Findings reveal …

Panda-Plus: Improved Dataset Of Prostate Whole Slide Images From Panda Challenge With Pixel-Level Expert Annotations, Spencer Hopson, Carson Mildon, Corbyn Kubalek, Joshua L. Ebbert, Ryan Vance, Lauren Laverty, Paul Urie, Dennis Della Corte

Faculty Publications

Artificial intelligence (AI)-based prostate cancer detection through whole slide images (WSIs) offers promising potential to address the global pathologist shortage while improving clinical consistency. Digital slides and improving image analysis methods encourage the creation of tools to aid in WSI classification. Despite promising advances, these tools are still limited by available training data. Current publicly available datasets, such as Kaggle's PANDA Challenge, while large in scale, rely on slide-level labels that may introduce noise and limit model reliability. Others contain detailed annotations, but are smaller in size due to manual processing efforts. In this work, we introduce PANDA-PLUS, a 546-image …

Synthesis Of Schiff Base Based On Aminopolysaccharides A Chitosan Apis Mellifera With Salicylic And Glutaraldehydes, Alisher Mengliev

Technical science and innovation

Chitosan is a linear aminopolysaccharide. Using methods of chemical modification of chitosan, a number of new biologically active materials have been created. The main interest in these products is due to the preservation of the basic physicochemical and biological properties of the original polymer and the acquisition of new properties depending on the nature of the introduced groups. Modified chitosan can be used in various fields such as drug delivery, textiles, wastewater treatment and a number of biomedical applications. The purpose of this work is to extract chitosan from the remains of ApisMellifera bees and synthesize a Schiff base with …

Lithological-Stratigraphic Characteristics And Prospects For Oil And Gas Potential Of The Mesozoic-Paleozoic Deposits Of The Muynak Uplift, Nursultan Sakenovich Kayupov, Marina Georgiyevna Yuldasheva, Shakhnoza Ulzhavaevna Eshmetova

Technical science and innovation

To increase hydrocarbon reserve growth, it is necessary to involve areas in the immediate vicinity of established oil and gas accumulation zones in geological exploration, as they developed under similar geological conditions within a single sedimentary basin. In the central part of the Ustyurt oil and gas region, deposits have been discovered in Jurassic sediments within the Berdakh swell, adjacent to the east by the Muynak Uplift. Analysis of available geological and geophysical data, including the study of lithological, stratigraphic, and reservoir properties, allows us to predict the oil and gas potential of Mesozoic rocks in this part of the …

Algorithm For Stabilizing The Reference Trajectory Of Self-Tuning Systems With A Reference Model, Isamidin Hakimovich Sidikov, Feruzakhon Botirxon Qizi Sodiqova

Technical science and innovation

The paper addresses the problem of stabilizing self-tuning systems using adaptive control methods based on a reference process model. As the optimality criterion, the functional of maximum speed of response is selected. The algorithm for synthesizing the self-tuning system is based on a relay-linear control law, which possesses the property of invariance to small disturbances. The issue of ensuring the practical stability of the system under adaptive and multiplicative disturbances is examined. An algorithm for the synthesis of a reference trajectory stabilization system has been developed on the basis of a quasi-optimal passive self-tuning system (STS) with a reference model, …

Treatment Of Textile Industry Wastewater By The Adsorption–Coagulation Method, Adkhamjon Rustamovich Makhkamov, Elmurod Abdukodirovich Egamberdiev, Muhammadzohid Abidjanovich Safaev

Technical science and innovation

This scientific article provides a systematic analysis of the composition of colored wastewater generated in cotton, wool, and silk textile enterprises, the sources of pollution, and modern physicochemical treatment methods. Wastewater formed during bleaching, dyeing, and wet processing is characterized by high concentrations of dyes, surfactants, organic and inorganic compounds, as well as colloidal particles. The main objective of the study is to determine the possibilities for effective treatment of colored wastewater using adsorbents obtained from local industrial wastes and to develop optimal technological regimes. In the course of the research, highly dispersed fly ash obtained from the Angren Thermal …

Comprehensive Assessment Of The Impact Of Hydrogeological Factors On The Stability Of Open-Pit Slopes, Vokhid Rakhimovich Kadirov, Khurshida Yunusovna Norova, Zavkiddin Yahyo Oglu Ravshanov, Jamol Hasankhonovich Abdumalikov

Technical science and innovation

This paper presents an analysis of the influence of hydrogeological conditions on the stability of open pit slopes located within zones of tectonic disturbance. Based on field investigations and long-term hydrogeological monitoring conducted within the Almalyk ore cluster (Kalmakyr, Yoshlik-I, and Kurgashinkan deposits), the key factors affecting slope stability have been identified. It has been established that groundwater inflows from fractured and karstified Paleozoic rocks, as well as the presence of flooded abandoned pits, significantly increase the risk of slope deformation and failure. A special role is attributed to tectonic faults, which act as filtration channels for groundwater, leading to …

Development Of Technical Solutions To Prevent The Formation Of Sludge Regime At The Bottom Of A Well, Rustam Umarkhanovich Juraev, Jonibek Tursunov

Technical science and innovation

The trouble-free process of drilling wells largely depends on the effective cleaning of the borehole. The formation of a slurry regime at the bottom of the well leads to the process of repeated crushing of drilling fines, which in turn leads to a decrease in the mechanical drilling speed, to an increase in the energy consumption of the rock-crushing tool for repeated crushing, and also increases the risk of oil seals. In addition, the formation of a slurry regime at the bottom of the well increases the intensity of abrasive wear of the drilling rig. This article provides a theoretical …

Mathematical Modeling Of The Atmospheric Water Harvesting Process Using Cfd, Jasur Esirgapovich Safarov, Shakhnoza Abduvaxitovna Shaxnoza, Doston Ishmuxammat Ugli Samandarov, Azamat Bakir Ugli Usenov, Shahzod Faxriddin Ugli Dostqobilov

Technical science and innovation

This article presents the physical principles of Atmospheric Water Harvesting (AWH) technologies, including spectral radiation balance, air-sorbent interactions, thermodynamic constraints, and computational fluid dynamics (CFD) modeling approaches. The study provides models of water condensation, adsorption-desorption processes, and energy consumption. In addition, a detailed thermodynamic analysis was carried out to determine the partial vapor pressure, cooling demand, and theoretical energy limits of water extraction. The adsorption process is described using Langmuir isotherms, while desorption is represented through a kinetic model dependent on activation energy. To analyze the coupled processes of airflow, mass transfer, and heat transport, CFD models based on the …

Detection And Correction Of Object Orientation On Production Lines Using Photodetector-Based Systems, Utkirjon Ubaydullayev, Elmira Raxmanova

Technical science and innovation

This article addresses the issue of errors occurring in high-speed production lines, particularly those caused by misalignment or incorrect positioning of manufactured objects. Although production lines have significantly enhanced industrial efficiency worldwide, they are not immune to mistakes, especially under rapid operation conditions. To mitigate these errors without human intervention, the proposed solution integrates photodetector sensor matrices with robotic manipulators. The system uses high-resolution photodetector arrays, such as the Hamamatsu S13774 CMOS Linear Image Sensor, to capture shadows of objects on the production line, converting these into numerical data. This data is then processed using Principal Component Analysis (PCA) and …

Study Of The Influence Of Material Heterogeneities In Humidity Measurements In A Closed Volume, Hulkar Asadullayevna Usmanova, Asadulla Turgunbaev, Umid Uralovich Xudaykulov

Technical science and innovation

The article presents generalized theoretical studies of the errors arising in the conversion of material moisture into informative parameters of the microwave field. Such informative parameters of a material include structural inhomogeneities, non-uniform moisture distribution throughout the volume and by the forms of moisture bonding, density, temperature, and mass. The influence of material inhomogeneities during moisture measurements in an enclosed volume on the errors of primary measuring transducers is investigated, along with the errors accompanying the conversion of moisture into the dielectric characteristics of the material and the conversion of dielectric characteristics into informative parameters of the microwave field. A …

Perbedaan Faktor Lingkungan Sosial Dan Perilaku Seksual Pranikah Pada Siswa Sma Perkotaan Dan Perdesaan Di Samarinda, Syaniah Syaniah, Annisa Nur Rachmawati, Lies Permana, Nur Rohmah, Rina Tri Agustini

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

Background. Based on the 2023 GSHS data, 7.1% of adolescents aged 13–17 in Indonesia have had sexual intercourse, of which 66.2% are male and 33.8% are female. Adolescent premarital sexual behaviour is influenced by internal and external factors. Differences in social determinants may lead to behavioural variations between groups within a population.

Aim. To identify differences in peer influence, parental roles, and mass media (as social environmental factors), as well as premarital sexual behaviour among urban dan rural high school students in Samarinda

Method. This comparative cross-sectional study involved 274 respondents, consisting of 206 respondents from three urban high schools …

Instrument Response Functions Of The Antarctic Demonstrator For The Advanced Particle-Astrophysics Telescope (Adapt), Wenlei Chen, James H. Buckley, Marion Sudvarg

Computer Science Faculty Research & Creative Works

The Antarctic Demonstrator for the Advanced Particle-astrophysics Telescope (ADAPT) gamma-ray/cosmic-ray instrument serves as a precursor to the proposed APT mission. The APT mission is designed to improve sensitivity in the MeV-TeV gamma-ray range by an order of magnitude compared to current missions and is optimized for dark-matter and multimessenger research. The ADAPT instrument uses scintillating fibers for particle tracking and sodium-doped cesium iodide (CsI:Na) tiles read out with wavelength shifting (WLS) fibers for imaging, with solid-state silicon photomultipliers (SiPMs) for calorimetry. It includes four layers of imaging calorimeter detectors and scintillating-fiber trackers, functioning both as a Compton and Pair telescope …

Performance Modeling And Improvements On The Grb Source Localization Streaming Pipeline Aboard The Antarctic Demonstrator For The Advanced Particle-Astrophysics Telescope (Adapt), Ye Htet, Ye Htet, Marion Sudvarg, Marion Sudvarg, Honghao Yang, Jeremy Buhler, Roger Chamberlain, Wenlei Chen, Wenlei Chen, James Buckley, Matthew Andrew, Blake Bal, Elisabetta E. Bissaldi, Richard G. Bose, Dana Braun, James H. Buckley, Jeremy Buhler, Eric Burns

Computer Science Faculty Research & Creative Works

The Advanced Particle-astrophysics Telescope (APT) is a mission concept for a space-based gamma-ray telescope whose capabilities include prompt localization of gamma-ray bursts (GRBs) to support multi-wavelength and multi-messenger astrophysics. ADAPT — APT's balloon-borne prototype — can localize GRBs in well under a second using on-board computing hardware. ADAPT will partner with ground-based, fast-slewing optical telescopes, rapidly providing alerts that enable the partner to observe a short-duration burst within a few seconds of detection. In this work, we investigate the utility of having ADAPT issue progressively more accurate location estimates for a GRB as detected Compton events from the burst accumulate …