Digital Commons Network^™

A Survey On Non-Invasive Computing: Neurological-Hematological Framework For Early Infection And Stroke Detection With Future Directions, Masud Rabbani, Nafi Us Sabbir Sabith, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

This paper introduces a novel, non-invasive tool for building a holistic neurological-hematological diagnostic framework that can be used for early detection of infection and stroke. We proposed and developed a multimodal sensing approach, where an ear canal–based acoustic system can be used to identify brain activities and a smartphone-based facial video analysis platform to estimate white blood cell (WBC) and hemoglobin (Hb) levels. Our ear-based EEG methodology achieved a remarkable 96% classification accuracy from the low-frequency level (>30hz), with regression models with mean R2 scores above 0.96 across all EEG bands. For hematological diagnostics, the system predicted WBC counts …

Fine-Tuned Large Language Models (Llms): Improved Prompt Injection Attacks Detection, Md Abdur Rahman, Hossain Shahriar, Guillermo Francia, Fan Wu, Alfredo Cuzzocrea, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

Large language models (LLMs) are becoming a popular tool as they have significantly advanced in their capability to tackle a wide range of language-based tasks. However, LLMs applications are highly vulnerable to prompt injection attacks, which poses a critical problem. These attacks target LLMs applications through using carefully designed input prompts to divert the model from adhering to original instruction, thereby it could execute unintended actions. These manipulations pose serious security threats which potentially results in data leaks, biased outputs, or harmful responses. This project explores the security vulnerabilities in relation to prompt injection attacks. To detect whether a prompt …

Reliability Of An Extended Version Of The 3m™ Eargage Tool To Assess Earcanal Size And Assist Earplug Selection, Bastien Poissenot-Arrigoni, Laurence Martin, Alessia Negrini, Djamal Berbiche, Olivier Doutres, Franck Sgard

Études primaires

Objective: Evaluate the ability of an extended version of the 3 MTM Eargage to estimate the earcanal size and assess the likelihood that a particular earplug can fit an individual’s earcanal, ultimately serving as a tool for selecting earplugs in the field. Design: Earcanal morphology, assessed through earcanal earmolds scans, is compared to earcanal size assessed with the extended eargage (EE) via box plots and Pearson linear correlations coefficients. Relations between attenuation measured on participants (for 6 different earplugs) and their earcanal size assessed with the EE are established via comparison tests. Study sample: 121 participants exposed to occupational noise …

Measuring Toluene Diisocyanate Concentrations In Accordance With Acgih® Inhalable Fraction And Vapor (Ifv) Notation, Charles Larocque, Pierre-Luc Cloutier, Sébastien Gagné, Loïc Wingert, Sylvain Canesi, Jacques Lesage, Simon Aubin

Études primaires

Toluene diisocyanate (TDI) is an irritant (skin, eye and respiratory) and a sensitizer. This compound is used to manufacture polyurethane materials such as flexible foams. The use of isocyanates may lead to exposure by inhalation and/or skin contact and isocyanates are recognized as a cause of occupational asthma. The American Conference of Governmental Industrial Hygienists (ACGIH^®) recommends a threshold limit value (TLV) for TDI of 1 part per billion (ppb) (7 µg m-^³) with inhalable fraction and vapor (IFV) notation. This notation means that the inhalable fraction of particles and the vapor phase of TDI may …

Survey Study On College Student’S Acceptance And Attitude Towards Generative Ai To Their Learning, Jinhua Wang

Selected Full Text Dissertations, 2011-

This study investigated college students’ attitudes and acceptance of generative AI tools like ChatGPT. These tools are advanced programs capable of understanding questions and responding in a conversational manner. The main objective is to determine whether college students find generative AI tools helpful for their learning and schoolwork. A comprehensive survey was conducted with 57 college students at an online survey platform SurveyMonkey.com. The survey solicited college students’ perceived usefulness of generative AI tools in academic settings regarding their school activities (such as writing papers, explaining complex topics, coding, solving math problems, and researching information). The model of Diffusion of …

Goodtimer For Good Behavior: A Nonconcurrent Multiple Baseline Examination Of A Behavioral Device Intervention To Reduce Child Misbehaviors, Morgan Weinstein

Selected Full Text Dissertations, 2011-

Behavioral Parent Training (BPT) effectively decreases disruptive behavior in children (Daley et al., 2014). Nonetheless, many parents perceive BPT to be challenging and demanding, leading to reports of high treatment dropout rates (Chacko et al., 2016.) To address this, the present study evaluated the effectiveness of Goodtimer, a behavioral health device utilizing contingency management, an element of BPT, to mitigate child disruptive behaviors. The Goodtimer is designed to make administering a contingency management system easier for parents. Employing a nonconcurrent multiple baseline design, the study assessed six families with children aged 3-9 years. Most parents who used the Goodtimer reported …

Show And Tell… Ing What?: Correlation And Moderation Analyses Of Public Displays Of Affection And Romantic Relationship Satisfaction, Communication, And Adult Attachment Styles, Samantha Brooks M.S.

Selected Full Text Dissertations, 2011-

Public Displays of Affection (PDA) amongst romantic couples are clearly shown in everyday life, though paradoxically, they are largely unexplored and therefore poorly understood. Not only is it unknown how PDA relates to other well-studied components of romantic relationships, but it is also unclear who engages in PDA. The present study investigated the relationship between public displays of affection and previously examined, fundamental components of romantic relationships including relationship satisfaction and attachment and communication styles. It then investigated the moderating effects of relationship satisfaction on respective communication and attachment styles and PDA. Sample size was 105 participants (N= 105). Students …

Attachment And Delusional Ideation: A Systematic Review And Proposed Model Of The Association Between Attachment Insecurity And Delusion Symptoms, Ryan Sparks M.S.

Selected Full Text Dissertations, 2011-

Early repeated child-parent experiences impact the emergence of children’s reality testing by providing them with secure, trusting relationships with reality-oriented caregivers in which beliefs can be evaluated and refined. These relationships facilitate open and reciprocal communication about thoughts and feelings. Caregivers facilitate the development of children’s reflective capacities by helping them connect their inner experiences to their behavior. This process encourages them to assess whether their thoughts and feelings accurately reflect reality by remaining attuned to the perceptions of reality that are shared with others. Given the centrality of early caregiving experiences to one’s development of reality testing, attachment theory …

Solution-Focused, Strengths-Based Practice: An Integrated And Future-Orientated Approach To Resistance In Child Protection And Welfare Service Users?, Susan Flynn Dr

Irish Journal of Applied Social Studies

This article presents a theoretical exposition of an integrated solution-focused, strengths-based perspective. It does so through a thematic review of literature. The proposition is that solution-focused, strengths-based techniques can offer practitioners useful modes of working with resistance in child protection and welfare service users. The issue of working well with service users who present as resistant to the work, is complex and challenging in child protection and welfare practice. Practitioners must strive for rigorous, humane and compassionate practice, which never distracts from or compromises child safety. A thematic review of literature on solution-focused, strengths-based practice is presented. Therein, relevant theoretical …

Sars-Cov-2 Variants Of Concern: Biological Implications Of Immunogenicity And Comorbidity, Jacob Nichols

Theses and Dissertations (ETD)

When coronavirus disease 2019 (COVID-19) emerged in human populations in late 2019, there was nothing known about the virus, SARS-CoV-2, besides that it had a high degree of similarity to severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV). The prior published research on these viruses set a strong foundation for the research approaches needed to quickly stand-up medical countermeasures for treatment of COVID-19. However, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) soon revealed a high propensity to evolve new variants that could engage host cell receptors with greater affinity and escape host immunity. With each wave …

Protein Kinase D1 In Myeloid Cells Promotes Disease Progression And Severity In S. Rectivirgula Induced Hypersensitivity Pneumonitis, John David Snyder

Theses and Dissertations (ETD)

Introduction: Hypersensitivity pneumonitis (HP) is an inflammation driven interstitial lung disease characterized by inflammation of the interstitium, bronchioles, and alveoli of the lung that leads to granuloma formation. Myeloid lineage immune cells play a critical role in the early and late stages of the disease, and this activity is mediated through toll-like receptors (TLRs) expressed by these cells. Protein kinase D1 (PKD1) has previously been identified as a critical signaling molecule in the TLR signaling pathways of all TLR family members except for TLR3. Our previous research found that activation of protein kinase D1 (PKD1) in the lungs following exposures …

Incarceration Reimagined: A Diversionary Option For Serious Felony Offenders, Jane Mitchell

Kentucky Law Journal

No abstract provided.

Democratization Of The Private Markets?, Colleen Baker, Christina M. Sautter

Faculty Journal Articles and Book Chapters

U.S. initial public offerings are declining and the amount of private market assets under management are exploding. Simultaneously, the number of retail investors opening taxable brokerage accounts is increasing. Private market assets are hot. Everyone–both institutional and retail investors–wants in on the action. Yet considerations such as financial resources and U.S. securities laws make such investment less accessible for many retail investors. In this short article, we explore this changing investment landscape and, specifically, one development within this craze: retail investments in private company shares via closed-end funds (or CEFs).

Recently, CEFs like ARK Venture Fund and Destiny Tech100, Inc. …

Is Originalism Bullshit?, Michael L. Smith

Faculty Articles

It’s finally time to answer the big question. This Article draws on the surprisingly robust literature examining the definition, essence, and significance of bullshit and evaluates whether originalist constitutional interpretation fits the bill. I begin with Harry Frankfurt’s definition of bullshit as utterances made in pursuit of the speaker’s goals without regard for their truth value. I also rely on alternate formulations, including bullshit as unclarifiable nonsense as well as contextual and audience-centric variations of bullshit.

While not all instances of originalism are bullshit, I identify those instances which are, and go on to demonstrate that originalism is uniquely prone …

Lost Fatherhood: Including Fathers In The Post-Dobbs Abortion Debate, Linda L. Schlueter

Faculty Articles

Scientific studies over the last five decades show the negative impact an abortion can have on the men who fathered the aborted children. These studies demonstrate that those men-even if they supported the woman's decision to have an abortion-can experience a variety of psychological problems including depression, anger, hopelessness, helplessness, broken or damaged relationships, feelings of emasculation, and loneliness. Despite these compelling studies, little or no real attention is given to involving men in the legal debate regarding abortion. The abortion debate presents a legal Rubik's Cube of thorny issues that can affect the mother, the father, and the unborn …

Rural Adolescent Girls' Experiences With Female Antiheroes: A Phenomenological Study Of Literature Discussions And Mentorship, Candice Kennedy Byers

All ETDs from UAB

This phenomenological research study focused on the experiences of rural adolescent girls reading female led multicultural young adult literature with the guidance of a female mentor teacher. Using two multicultural young adult novels one with a strong female protagonist and one with a female antihero protagonist, this five-week study sought to explore the lived experiences of 14 adolescent girls in the rural Southeast. The theoretical frameworks of Radical Feminism (Lawford-Smith, 2022; hooks, 2015; Kreps 1972; Rhodes, 2005), Critical Race Theory (Crenshaw, 1988; Ladson-Billings. 2003; Delgado, 1989; Harris 1993), and Multicultural Young Adult Literature (Nieto, 2002; Fox & Short, 2003; Boyd …

Reelin Regulation Of Striatal Physiology And Cocaine Reward, Kasey Lynn Brida

All ETDs from UAB

Drugs of abuse activate defined neuronal populations in brain reward structures such as the nucleus accumbens (NAc), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. While the molecular and cellular effects arising from experience with drugs like cocaine are increasingly well understood, the mechanisms that sculpt NAc neuron participation are largely unknown. Here, we leveraged unbiased single-nucleus transcriptional profiling to identify expression of the secreted glycoprotein Reelin (encoded by the Reln gene) as a marker of cocaine-activated neurons within the rat NAc. Multiplexed in situ detection confirmed selective expression of the immediate early …

Evaluation Of The Niosh Sound Level Meter App In Real Work Settings, Maxwell Scott Costlow

All ETDs from UAB

With the significant presence of occupational noise exposure, the development of mobile sound measurement applications has been reported. These apps have the potential to help reduce purchasing costs of sampling equipment for small businesses. One of the most promising apps is the National Institute for Occupational Safety and Health (NIOSH) Sound Level Meter (SLM), but most studies on the accuracy of the app have been conducted in controlled labs. The purpose of this study was to examine the differences between the NIOSH SLM and type 2 noise measuring instruments in real work settings. Both short-term and long-term noise sampling was …

Platal Expansion Using The Invisalign Palatal Expander "Ipe", Hassan Chihab

All ETDs from UAB

Palatal expansion has been used in orthodontics to treat a narrow maxilla and to primarily correct posterior dental crossbites. In younger patients, palatal expansion can readily be achieved through opening of the mid-palatal suture, as it is not fused at that age. As the mid-palatal suture matures, expansion will gradually be difficult to achieve, and more dental expansion is obtained rather than skeletal. In addition, there is a tendency to get more dental tipping. Palatal expansion has been recommended not only to correct crossbites but also to improve breathing in patients with sleep disorders such as obstructive sleep apnea (OSA). …

Context-Dependent Functional Connectivity During Attention Orienting And Reorienting: Comparing Individuals With Schizophrenia And Controls, Hyun Freeman

All ETDs from UAB

Attentional deficits are a well-established feature of schizophrenia, impacting various functional domains. Previous research suggested altered connectivity within attention networks may underlie these deficits, but few studies have examined how these net-works dynamically interact during different types of attention processes. In this study, we investigated functional connectivity patterns during attentional orienting and reori-enting to social and nonsocial cues in 25 individuals with schizophrenia and 25 controls. Participants completed a modified Posner spatial cueing task with both social (eyes) and nonsocial (arrows) cues during fMRI scanning. Using generalized psychophysiological interaction analysis with the left lateral occipital cortex (LOC) as a seed …

Discarded People, Amber Harris

All ETDs from UAB

ABSTRACT This is the first chapter of the novel, Discarded People, a character-driven story about a group of young Black friends navigating love, identity, and community. As they form deep connections with one another, they face personal struggles that challenge their sense of belonging and self-discovery. The narrative explores themes of family, friendship, and the search for purpose, while highlighting the complexities of building a chosen family amidst personal and societal pressures. In chapter one, the main characters are introduced; Winnie, Franklin, Jelani, Adanna, Eban and Chance. As the characters prepare for their final year in high school while navigating …

Development Of A Resistive Force Paradigm For The Treatment Of Hemiparesis, Jonathan Daniel Hill

All ETDs from UAB

Hemiparesis is weakening of one side of the body as a result of a stroke that contributes to a decrease in propelling forces (i.e. propulsion) while walking. Existing research to improve propulsion of individuals post-stroke has implemented single-belt and split-belt treadmills, various walking speeds, asynchronous belt speeds (on split-belt treadmills), and a variety of methods for inducing resistive force upon a paretic limb in an attempt to strengthen the paretic limb and improve overall gait symmetry. However, despite this concerted effort of clinicians and scientists, gait deficits remain. Novel methods are required to improve reduced propulsion of individuals post-stroke. Recently, …

The Role Of Aquaporin-3 Lysine 282 Acetylation In Renal Water Balance, Nha Van Huynh

All ETDs from UAB

Aquaporin-3 (AQP3) mediates basolateral water transport in the kidney collecting duct principal cells, contributing to vasopressin-mediated urine concentration. We previously identified a novel post-translational modification of AQP3, the acetylation of lysine 282 (K282), which we hypothesized as a positive regulator of AQP3 water permeability. First, we found that collecting duct K282 acetylated AQP3 increased upon water deprivation, suggesting an involvement in renal water balance. To decipher the functional role of this modification, we utilized AQP3 acetylation (K282Q or Q) and deacetylation (K282R or R) mimetic mutant mice models generated using CRISPR/Cas9 knock-in technology. Both male and female wild-type (WT) and …

Analysis Of Gas Station Drugs Using Gas Chromatography Mass Spectrometry And Fourier Transform Infrared Spectroscopy, Megan Joos

All ETDs from UAB

Gas stations and head shops are a seemingly safe and legal marketplace for drug purchase. However, although marketed as dietary supplements or cognitive enhancers, the products sold there have been known to contain psychoactive substances which may be mislabeled or actually contain regulated substances. This study investigates the composition of such products, specifically those labeled as kratom and non-kratom Mitragyna species using gas chromatography-mass spectrometry (GC-MS) and those labeled as phenibut using GC-MS and fourier transform infrared spectroscopy (FTIR). Samples were acquired from retailers in the Birmingham, AL area. The products underwent both qualitative and quantitative analysis of their ingredients …

Investigating The Role Of Notch1 On Cell Viability In Pancreatic Neuroendocrine Tumor Cells In Hypoxia, Alexis Kennedy

All ETDs from UAB

INVESTIGATING THE ROLE OF NOTCH1 ON CELL VIABILITY IN PANCREATIC NEUROENDOCRINE TUMOR CELLS IN HYPOXIA ALEXIS KENNEDY MULTIDISCIPLINARY BIOMEDICAL SCIENCE ABSTRACT Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms originating from neuroendocrine cells in the pancreas. Patients with advanced disease pose a complex challenge due to poor prognosis and limited treatment options. Notch signaling is a juxtracrine cell-cell communication mechanism whereby transmembrane Notch receptors (Notch 1-4) interact with neighboring cells through ligands binding, resulting in a cascade that regulates various developmental processes and cell fate decisions. Dysregulated Notch1 signaling is implicated in PNETs, affecting neuroendocrine tumor biology and potentially interacting with …

Evaluation Of In Vitro Cardiac Models For Characterizing The Role Of Autophagy In Streptococcus Pneumoniae Infection, Georgianna Khong

All ETDs from UAB

Streptococcus pneumoniae (Spn) is a gram-positive bacterium that causes community-acquired pneumonia, the most prevalent type of pneumonia and a predominant infectious disease. There is evidence linking Spn infection to cardiovascular damage through the ability of Spn to invade and replicate in the myocardium, inducing cardiomyocyte death and disrupting cardiac function. Spn infects cardiomyocytes intracellularly through clathrin-mediated endocytosis, with demonstrated evidence of inhibitory mechanisms including clathrin-mediated endocytosis inhibitors and antioxidants. As a result, autophagy is being investigated as a potential pathway for cardiomyocyte self-defense against Spn, as it may protect cardiomyocytes intracellularly. The primary objective of this study was to evaluate …

Optic Nerve Head Remodeling In Experimental High Myopia, Mahmoud Khalafallah

All ETDs from UAB

Myopia is a global health concern, with projected estimates that nearly half of the world's population will be myopic by 2050. While its refractive aspect can be corrected, the heightened susceptibility to sight-threatening comorbidities, particularly with high myopia, remains a challenge. Among these comorbidities, glaucoma is a major concern, with myopia recognized as an independent risk factor. However, the mechanistic link between myopia and glaucoma remains poorly understood. This dissertation investigates the multiscale remodeling changes in experimental high myopia and their potential implications for increased risk of glaucoma later in life. Using a multimodal approach, this dissertation investigates: (1) neural …

Accuracy Of 3d Printed Models With Various Range Of Crowding Created By Dlp Printer With Different Designs Of Model Base, Chih Yen Liu

All ETDs from UAB

Objective: Treatment planning and appliance fabrication depend on the accurate representation of dentition. Research on the accuracy of digital light processing (DLP) printed models with different base designs across various levels of dental crowding remains limited. This study aims to evaluate the fidelity of DLP printed models and the suitability of different base designs for representing dentition with mild, moderate, and severe crowding. Materials and Methods: The objective is to determine the optimal base designs for DLP-printed models to address varying degrees of dental crowding. A two-way ANOVA was used to compare root mean square (RMS) error across different base …

An Investigation Into The Effects Of Preservatives On Ss-Hydroxybutyrate Concentrations Measured By Commercial Ketone Meter And Gas Chromatography-Mass Spectrometry, Kerry F. Murr

All ETDs from UAB

Ketoacidosis occurs when fatty acids are metabolized into ketone bodies in the liver and released into the bloodstream. This condition, which can be fatal, is commonly observed in diabetics, alcoholics, and individuals who experienced starvation or hypothermia. Although the ketone ß-hydroxybutyrate (BHB) is an accepted biomarker of ketoacidosis, the effects of preservatives on BHB concentrations in postmortem blood are unaddressed. The first aim of this research was to determine whether preservatives affect ketone levels as measured by a point-of-care device. Paired preserved and unpreserved blood samples were obtained from the Jefferson County morgue: preserved samples in grey top tubes and …

Exploring Gaps In Hiv Prevention: Hiv Pre-Exposure Prophylaxis Awareness, Attitudes, Utilization, Coverage, Hiv Testing And Risk Perception Among Sub-Saharan African College Students In The United States, Ikenna Obasi Odii

All ETDs from UAB

This dissertation focuses on increasing HIV awareness and contributing to efforts at reducing new HIV infections among Sub-Saharan African (SSA) college students. It begins with an introductory chapter one and ends in the concluding chapter five. Chapter two presents a systematic review identifying key gaps in HIV Pre-Exposure Prophylaxis (PrEP) knowledge, attitudes, and utilization among Black college students in the United States (U.S). The review synthesizes findings from four studies, revealing that a third of participants demonstrated adequate PrEP knowledge, while PrEP utilization remained under-utilized at three percent. Key barriers to PrEP uptake included fear, low self-perceived HIV risk, infrequent …