Digital Commons Network^™

Effects Of Maternal Overnutrition And Metabolic Challenge In Adult Life On The Histological Integrity Of The Liver And Intestinal Epithelium In Rabbits, Lucía Carolina Cano, Erika Navarrete, Pedro Medina, Juan Pablo Ochoa-Romo, Georgina Díaz, Rodrigo Montúfar-Chaveznava, Rosa María Vigueras-Villaseñor, Ivette Caldelas

Artículos científicos

Introduction: Maternal overnutrition during critical stages of embryonic development has been implicated as a major determinant of developmental and metabolic disturbances in offspring. Current data concerning how perinatal exposure to high-fat and high-carbohydrate diets, followed by re-exposure in adulthood (metabolic challenge), affects the metabolic regulation and structural integrity of the liver and small intestine, key organs of the gut–liver axis (GLA), are limited. Methods: Female rabbits were fed either a standard diet (SD) or a high-fat and high-carbohydrate diet (HFCD) before mating and during gestation. The offspring on postnatal day 440 were challenged with an HFCD or SD for 30 …

Driving Complex Thinking And Technological Entrepreneurship With Artificial Intelligence: A Mixed Methods Study, Inés Alvarez-Icaza, J. Miranda, A Martínez-Arboleda, P Suarez-Brito, María Soledad Ramírez-Montoya

Artículos científicos

AI technologies offer unique capabilities that enhance collaboration and creativity among students by providing novel insights, generating diverse perspectives, and triggering the development of innovative thinking as a subcompetency of the mega-competency of complex thinking. Regarding entrepreneurial skills development, applying AI-powered tools, such as natural language processing on digital educational platforms, allows students to engage in dynamic ideation processes for entrepreneurial projects with social, technological, and scientific approaches. This article explores the application of artificial intelligence (AI) as a valuable resource for fostering creative idea generation within co-creation strategies for university students. In a mixed-method analysis, we obtained valuable information …

Spike Train Analysis In Rehabilitation Movement Classification Using Deep Learning Approach, Fadilla Atyka Nor Rashid, Marizuana Mat Daud, Nor Surayahani Suriani, Mahidur R. Sarker, Maher G. M. Abdolrasol, Hassan Abdurrahman Shuaibu, Taha Selim Ustun

Artículos científicos

The rapid advancement of sensor technologies has sparked significant interest in intelligent physiotherapy monitoring systems, which hold immense potential for improving assessment quality. Despite this promise, existing sensor technologies for physiotherapy evaluation often need to be expanded in their versatility and robustness. This research introduces an innovative approach using spike train feature extraction to enhance patient progression tracking for physiotherapy assessment. developed a novel approach that reveals distinctive patterns for each physiotherapy exercise by implementing spike trains as the primary feature extraction method. The methodology used three datasets: UI-PRMD, K3Da, and a Self-Collected dataset, which were encoded into spike train …

Gender Differences In Psychological Strengths Among Rural Adolescents, Angela Preston, Jodi Bullard, Rachel Smith, Ashlyn Peppler

Nursing Faculty Publications and Presentations

Purpose: Rural adolescents often lack access to mental health care along with increased rates of depression and suicide completion. While psychological strengths have been associated with positive outcomes globally, little is known regarding the prevalence of these indicators (hope, self‐efficacy, resilience, optimism, and gratitude) among adolescents living in rural Texas. The purpose of this study was to describe how rural adolescents report their psychological strengths and examine the data for potential gender differences.

Design and Methods: A secondary analysis of cross‐sectional data was performed on the RStudio platform using tests of central tendency and inferential statistics. Results: There were 425 …

Pilot Study Of The Barriers To Exercise Adherence And Motivation (Beam) Questionnaire For Adults With Osteoarthritis, Haley Ciara Hughes

Dissertations

Osteoarthritis (OA) is a chronic condition affecting over 33 million adults in the United States (Center for Disease Control and Prevention [CDC], 2024). While exercise is one of the leading, non-pharmacological treatments for OA (Zhang et al., 2008), patients often struggle to meet physical activity guidelines, increasing their risk of lifelong disability, falls, and dependence (Wallis et al., 2013). Researchers in physiotherapy have struggled to identify effective, individualized treatments to improve exercise adherence for patients with OA that maintain long-term effects (Ezzat et al., 2015); an area behavior analysts could offer insight and guidance. Behavior analysts have developed indirect functional …

Assessing Patient Experiences And Priorities In Traumatic Brain Injury Health Care, Temitayo R. Okusanya, Madeline D. Furie, Sergey Tarima, Courtney O. Barry, Terri Deroon-Cassini, Yuka Kobayashi, Michael A. Mccrea, Kathleen S. Williams, Staci A. Young, Lindsay D. Nelson

Biostatistics Faculty Publications

Improving patient experiences and outcomes of traumatic brain injury (TBI) will require understanding patient perspectives of current care systems. Experts have called for building more integrated, patient-centered systems of care to better support patients through stages of TBI recovery. Informed by an earlier qualitative study, we conducted a survey to quantify patient perspectives on discharge and post-discharge experiences across seven hospitals in a single southeastern Wisconsin health system. Eligible participants were English or Spanish speakers and received TBI care between February 2023 and June 2024 at one level I trauma center emergency department (ED) and inpatient unit, two level III …

Quantifying Nuanced Differences In Hand Dexterity Between The Dominant And Nondominant Hands Of Healthy, Right-Handed, Young Adults, Brian J. Conway, Léon Taquet, Timothy F. Boerger, Kaitlin Goetschel, Kate B. Krucoff, Sergey Tarima, Brian D. Schmit, Max O. Krucoff

Biostatistics Faculty Publications

When individuals present with hand injuries, clinicians often use the contralateral hand as an internal control. However, subtle differences in baseline dexterous abilities between the dominant and nondominant hands are poorly understood. To address this gap, here we quantified such differences, measured as independence (individuation) and smoothness of finger movements. A cohort of 47 right-hand-dominant healthy adults (22 males and 25 females) moved each finger independently 10 times, while joint angle data were tracked with a dataglove (CyberGlove III, CyberGlove Systems, San Jose, CA). Each finger’s performance was compared with its counterpart on the opposite hand using Wilcoxon-signed rank tests. …

Development Of Novel Small Molecule Therapeutics For Myotonic Dystrophy, Xhesika Azis

Biological Sciences

Myotonic Dystrophy type 1 (DM1) results from expanded CUG repeat RNA that sequesters MBNL proteins and disrupts alternative splicing. Small molecules that bind toxic repeat RNA and release MBNL proteins represent a promising therapeutic strategy. This thesis examines newly synthesized modified polycyclic compounds (MPCs) engineered to target CUG RNA with enhanced specificity and efficacy. Through Suzuki–Miyaura coupling and benzoquinone-mediated cyclization, MPC03 was synthesized and characterized by NMR and LC–MS.

The biological activity of these compounds was assessed in DM1 patient-derived myotubes and fibroblasts. MPC03 consistently produced dose-dependent rescue of multiple MBNL-regulated exons, restoring splicing patterns toward those observed in healthy …

Experimental Characterization Of An Additively Manufactured Porous Gyroid Air-Cooled Heat Sink, Grant S. Resler

Mechanical Engineering Undergraduate Honors Theses

This paper presents the development of a ducted test facility designed to evaluate heat sinks efficiency at varying air velocities. This enables the evaluation of both heat transfer and pressure drop performance. These metrics are essential to the overall efficiency of heat sinks and help identify the optimal air velocity to achieve the desired thermal performance. A standard plate fin heat sink was used as a control for comparison to a novel heat sink. The specialized heat sink geometry was generated using nTop, a generative design software focused on additive manufacturing. This design was fabricated via Direct Metal Laser Sintering …

Leveraging Virtual Reality In Nursing Education To Enhance Confidence And Knowledge, Kerry Vaccaro, Amanda Bodinet, Concetta Zak

Biennial Convention (CONV)

Blood transfusion reactions can be life threatening and are rarely encountered by nursing students in clinicals. Simulation has been shown to have a positive impact on transfusion-related competence in nursing students (Brown, C. & Brown, M., 2023). BSN nursing students faced challenges in recognizing and responding to blood transfusion reactions. A Virtual Reality (VR) simulation was introduced as an innovative teaching modality. Virtual Reality provides learners with a more life-like experience that is standardized and safe (Kiegaldie & Shaw, 2023). The purpose of this study was to evaluate whether VR simulation, compared to traditional lecture, improves senior-level BSN students' confidence …

Goodbye Textbook: Content Creation For A Non-Clinical Nursing Course Using Ai Tools, Julie Kientz Elting

Biennial Convention (CONV)

Purpose: To provide guidance for faculty interested in creating materials using AI tools for nursing courses which allows ‘unadoption’ of textbooks.

Background: When discussing AI text generation tools like ChatGPT and Gemini (AI tools), many nursing faculty are only aware of the risks to academic writing (Abujaber et al., 2023). But there are many pedagogical benefits of AI tools that enhance student learning (Elting & Desio, 2024; Glauberman et al., 2023; Srinivasan et al., 2024) and manage faculty teaching, communication, and administrative tasks (Srinivasan et al., 2024). What is less known is how AI tools can be used to create …

A Study On Utilizing Coherently Coupled Orbital Angular Momentum Beams For Maritime Sensing And Communication, Evan Robertson

All Dissertations

A large portion of the world is covered in water which introduces a couple of key challenges in communication and sensing systems. The impact of particulates in the water will limit the ability to successfully transmit information through the water. The study of how the channel impacts specific frequencies and the ability to transmit more information at a single time can limit the impact of this environment in how it degrades an optical communication system. In sensing applications, it is important to detect information related to an object’s motion which will either be towards or away from a system, or …

Acute Effects Of Lactate Infusion On Metabolism, Ad Biomarkers, And Cognition, Riley E. Kemna, Paul J. Kueck, Anneka Blankenship, Casey S. John, Chelsea N. Johnson, Zachary D. Green, Hana Mayfield, Lauren Yoksh, Lance Johnson, John P. Thyfault, Jonathan D. Mahnken, Benjamin F. Miller, Jill K. Morris

Physiology Faculty Publications

BACKGROUND: Impaired cerebral glucose metabolism is a hallmark of Alzheimer's disease (AD). Lactate is an alternative brain fuel; however, whole-body lactate metabolism has not been measured in AD. METHODS: The Lactate for Energy and Neurocognition Trial (NCT05207397) was a single-arm trial that enrolled 24 cognitively healthy (CH) older adults and 12 cognitively impaired (CI) participants. Subjects underwent a stable isotope lactate infusion to evaluate lactate metabolism, cognitive testing, and blood biomarker analyses. pTau217, brain-derived tau (BD-tau), pTau181, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), total tau, and brain-derived neurotrophic factor (BDNF) were analyzed by Simoa HD-X (Quanterix). RESULTS: …

Best Practices: Lean Thinking For Corn And Soybean Farmers, Tomas Gutierrez, Henry Quesada

Purdue Extension Numbered Publications

This article presents a practical introduction to lean thinking for corn and soybean farmers. Lean is a proven management approach that helps reduce waste, organize workspaces and improve the use of time, tools, and materials. Although it began in manufacturing, lean has been successfully adapted to agriculture through simple, low-cost tools that focus on improving everyday tasks.

The guide explains six key lean tools — 5S, Kanban, Visual Controls, TPM, Standardization, and Kaizen — with real farm examples and step-by-step recommendations. It also offers advice on how to get started, involve workers and measure improvements using basic indicators.

Lean thinking …

Recording Alternative Rock Guitar: Gear, Techniques, And Implementation, Alberto De Jesus Garcia Padilla

Capstone Projects and Master's Theses

This paper examines the tools, techniques, and creative decisions involved in recording alternative rock guitar, with particular attention to how genre defining sounds are achieved through gear choice, signal chains, microphone placement, and digital workflows. Drawing on historical context and influential alternative rock artists, the study outlines common guitars, amplifiers, pedals, and recording practices associated with the genre. These concepts are then applied to a practical case study: the recording of guitar parts for the band Phone Booth. By combining traditional amplifier recording with modern digital amp modeling, this project demonstrates how alternative rock guitar tones can be achieved without …

Empowerment Or Imprisonment? The Line Between Sex Work And Sex Trafficking: A Comparison Of Law Enforcement And Academic Perspectives, Jocelyn Belcastro

Theses/Capstones/Creative Projects

This research explores the line between consensual sex work and sex trafficking to gain a better understanding of the prevalence and pathways through which sex work may transition into sex trafficking. Semi-structured interviews were conducted with law enforcement professionals that work closely with survivors of sex trafficking to examine the pathways from consent to coercion. An interview with a former sex worker, now college professor, was also conducted to examine the lived experience and academic perspective. Both the law enforcement and academic perspectives were analyzed and compared to one another to form a nuanced understanding of the complex issue of …

Comparative Analysis Of The Effects Of Peppermint Oil On Colorectal Cancer Cells And Human Fibroblasts, Allen W. Mccumbers

Theses/Capstones/Creative Projects

This study contrasted the effects of Peppermint Oil on two cell lines, HT29s (colorectal adenocarcinoma cells) and HFFs (Human Foreskin Fibroblasts). Cytotoxic as well as genomic effects were compared between the cell lines. Trypan Blue, Alamar Blue, and qPCR assays were used to study these effects. Both cell lines were treated with a range of Peppermint Oil concentrations, and it was determined that there is a dose-dependent factor associated with cytotoxicity. To confirm results, Alamar and Trypan Blue assays were repeated at 300 and 500 cells/mL respectively. Effects were confirmed, and results were averaged and plotted. Alamar Blue revealed that …

Holistically Analyzing The Initial Athlete-Provider Interaction During Sports Injury Diagnosis, Tyler Baldwin

Theses/Capstones/Creative Projects

Recovering from injury is crucial for an athlete’s health-related quality of life and mental health. A potentially significant moment that could influence an athlete’s mindset towards recovery is the interaction between the provider and athlete during initial diagnosis. To analyze this moment from both perspectives, this study performs a thematic analysis of five semi-structured provider interviews and ten athlete interviews. In this study, all five providers exemplified an understanding of this moment’s significance, expressing awareness of their potential impact on the athlete’s mindset, and emphasizing mutual understanding to ensure streamlined recovery. Meanwhile, all ten of the athletes expressed self-awareness regarding …

Cal Poly Semester Conversion Time Capsule, Maximus La Via, Matthieu Gol, Viki Sarmasi, Tuyetthuc Nguyen

Mechanical Engineering

As Cal Poly transitions from the quarter system to the semester system, aligning itself with the other California universities, the idea has been proposed to commemorate this moment in the history of the university with a time capsule. The time capsule will be on display on the first floor of the library for a few years and later moved into the library’s archive room for permanent storage. 50 years after the completion of the semester conversion project, the time capsule will be opened. This project aims to create a secure and aesthetic device capable of storing and protecting memorabilia from …

Exploratory Diver Geotechnical Equipment (Edge), Angel Villicana, Merrick Zellers, Erik Heuchert, Lucas Heuchert

Mechanical Engineering

The goal of this report is to showcase how our final Core Sampler design and prototype address the needs of Navy Divers. Geotechnical equipment for Navy divers has not been updated since the early to mid-1980s, resulting in imprecise and outdated sampling methods. The primary purpose of this project is to enhance, modernize, and redesign a tool to collect a minimally disturbed core sample of the seabed for geotechnical evaluation. This report presents the full development of our project from concept to verification and final outcomes. It begins with the statement of disclaimer, followed by a four-panel executive summary and …

Clark Memorandum: Fall 2025, J. Reuben Clark Law School, Byu Law School Alumni Association, J. Reuben Clark Law Society

The Clark Memorandum

• Our Constitutional Anchor
• Divine Law
• The Courage of Our Convictions
• Our Call to Action

Intentional Improvement Through 3d Environment Art, Samuel T. Pinnex

Master of Fine Arts in Digital Media Culminating Experience

The idea of self-growth can be exciting—the thought of where one might be in the near or distant future is exhilarating. As an artist, this is even more apparent. On the other side of that coin, the realization that it is all up to you can oftentimes be overwhelming. We all want to improve, and we want our work to improve with us as a showcase of that improvement. Over the past two years, I’ve learned how valuable it is to adopt a “growth mindset”. Once I became comfortable with this idea, the responsibility for my own self-growth no longer …

The Absence Of Something: Addressing Underrepresented Lgbtqia+ Communities In Video Games Through Holistic Character Design Techniques, Lydia Myers

Master of Fine Arts in Digital Media Culminating Experience

This research identifies pain points and gaps in current LGBTQIA+ representation in the video games industry, and showcases the characters that I have created in response to those pain points. Despite the games industry representing LGBTQIA+ individuals often, certain communities under the umbrella are included less often, less accurately, and less respectfully than others. The goal of this research is to identify important considerations for respectfully portraying underrepresented queer communities in video games: specifically transgender, nonbinary, asexual, aromantic, and polyamorous communities, which are especially under-explored. My included characters were created via a holistic approach to character design. Despite my professional …

Methodologies For Generating Passive Income As A Digital Artist, Levi Stone

Master of Fine Arts in Digital Media Culminating Experience

This research provides an in-depth exploration of 3D workflow methodologies for digital merchants, how and why to implement them, and their correlation with passive income earnings. Digestible strategies regarding the development, packaging, marketing, and sale of assets for digital marketplaces are explored at length. Motivated by the state of the digital media industry, this research demonstrates that secondary income is possible through consistent, applied methodologies. Topics include environmental storytelling, the importance of being user friendly, material variance, and much more. The author demonstrates the impact of reframing your approach when designing products with the intention to sell, and explores the …

“For Whom The Bell Tolls”?* Is The Corporate Transparency Act Dead, And If Not, What Is Its Impact On Corporate Governance?, Kellen Ware

UC Law Business Journal

The Corporate Transparency Act (“CTA” or “the Act”) was enacted by Congress in 2021 to combat illicit financial activity through mandated beneficial ownership disclosure. While the current administration has opted not to enforce the CTA’s reporting requirements on domestic entities, the law remains in effect, and its future is uncertain amid ongoing constitutional litigation.

This Note argues that the CTA should be repealed, and state legislatures should refrain from mirroring the Act. The CTA creates undue burdens that threaten effective and efficient corporate governance in small businesses and many non-profits. This Note traces the contentious history of the CTA and …

Alaska Native Disparities In Alaska Jails And Prisons. An Exploratory Study And Descriptive Analysis, Brad A. Myrstol, Cheryl Jones, Rus'sel Sampson, Bri Moffat

AJiC Reports

This report presents an exploratory study of racial disparities in Alaska’s correctional system, combining a review of national research with an analysis of Alaska Department of Corrections (ADOC) booking data.

Exploring The Fusion Of Montessori And Waldorf Pedagogies For Early Literacy Interventions In Children With Autism: Non-Exhaustive Literature Review, Chiquila Q. Dolison

Institute for Disability Studies

No abstract provided.

Identifying Barriers For Community Pharmacies As Vaccines For Children (Vfc) Providers In Rural Alabama: Opportunities For Solutions, Myra Bajwa

Honors Theses

Significant Human papillomavirus (HPV) vaccination disparities exist between rural and urban areas in the US. A primary contributor is low access to preventive care in rural areas. Among the most promising strategies to overcome this is increasing access through offering HPV vaccination in non-traditional, convenient health settings such as pharmacies. In rural areas, community pharmacies are trusted, convenient pillars of the community. In Alabama, community pharmacies are eligible for enrollment in the Vaccines for Children (VFC) Program, a federally-funded program that provides free vaccines to children and adolescents under 18 years old who are uninsured, underinsured, American Indian, or Alaska …

Best Practice Recommendations For Anesthesia Providers In Preventing Postoperative Delirium In The Geriatric Population Undergoing Non-Cardiac Surgery, Ana Primeaux, Ashanti Reed

Doctoral Projects

Postoperative delirium (POD) is a significant and preventable complication in geriatric patients undergoing non-cardiac surgery. Such complication is associated with foreseeable consequences, such as prolonged hospitalization, long-term cognitive decline, increased morbidity and mortality, and increased costs. Despite the emerging awareness of evidence-based nonpharmacologic and pharmacologic interventional strategies, POD still represents a clinical challenge for anesthesia providers.

Currently, there is a lack of clinical guidelines to guide formalized education and evidence-based interventions on POD prevention across anesthesia practice settings. Consequently, there is a critical need to raise awareness that the lack of clinical guidelines and the high incidence of POD may …

Advancing Anesthesia Provider Proficiency In Airway Assessment Using Point-Of-Care Ultrasound: An Osce-Based Educational Initiative, Austin Fike, Trevor Jordan, Sam Sherrill Iii

Doctoral Projects

Airway management is one of the fundamental pillars of anesthesia. Traditionally, tools such as the Mallampati classification and the thyromental distance are used for airway assessment in the perioperative area. However, often, these methods fail to reliably predict difficult intubations. The use of point-of-care ultrasound (POCUS) has emerged as a valuable adjunct in airway assessment. However, a knowledge deficit exists among anesthesia providers regarding its application in airway assessments for perioperative adult patients. This doctoral project addressed the knowledge deficit in POCUS airway assessment among Certified Registered Nurse Anesthetists (CRNAs) and Student Registered Nurse Anesthetists (SRNAs) through the development and …