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Clinical Decision Support For Pharmacologic Management Of Treatment-Resistant Depression With Augmented Large Language Models, Martha Sajatovic

Faculty Scholarship

Background: We evaluated whether a large language model could assist in selecting psychopharmacological treatments for adults with treatment-resistant depression. Methods: We generated 20 clinical vignettes reflecting treatment-resistant depression among adults based on distributions drawn from electronic health records. Each vignette was evaluated by 2 expert psychopharmacologists to determine and rank the 5 best next-step pharmacologic interventions, as well as contraindicated or poor next-step treatments. Vignettes were then presented in random order, permuting gender and race, to a large language model (Qwen 2.5:7B), augmented with a synopsis of published treatment guidelines. Model output was compared to expert rankings, as well as …

Enhanced Sensory Perception And Myoelectric Control With High Channel Count Implanted Sensorimotor Systems, Sedona R. Cady, Joris Lambrecht, Dustin J. Tyler

Faculty Scholarship

Objective. Implanted electrodes for nerve stimulation and myoelectric recording facilitate bidirectional sensory feedback and control for neuromuscular conditions such as limb loss. While increasing implanted electrode channel count offers potential benefits, it also presents engineering and implementation challenges. This case study examines how increasing implanted electrode channel count affects sensory perception and myoelectric controller performance, thereby supporting the value of these advancements. Approach. One participant with upper extremity transradial limb loss received a percutaneous implanted system with two 8-channel extraneural cuff electrodes on the median and ulnar nerves, totaling 16 stimulating channels. The individual later received a wirelessly connected implanted …

Effects Of Commission Errors During Prompting On Skill Acquisition And Maintenance, Molly K. Mutchler

Dissertations

Procedural fidelity refers to the extent to which procedures are implemented as intended. Engaging in procedural fidelity errors can lead to detrimental outcomes during skill acquisition and maintenance. The purpose of this study was to parametrically evaluate and compare two commission errors during prompting procedures using an arbitrary tacting task taught to college-aged students. Participants learned to tact four sets of arbitrary pictures and names. Prompting errors consisted of either providing the correct letters for a name in an incorrect order (i.e., an error within a component of the name) or providing the correct name for another picture (i.e., an …

Environmental Beliefs Among Evangelical Leadership, Jeffrey Stark

Dissertations

There has been consensus among climate scientists for over a decade about the reality of human caused climate change. Even with this consensus, the public understanding of this issue remains divided based on factors generally unrelated to the science. Evangelical Protestants are one group which consistently polls as more skeptical of climate change. This is true not only when compared to the general population but also when compared to other religious demographics. Most large-scale surveys of evangelicals assume the demographic to be a monolith and do not attempt to break the demographic down further. In this mixed methods study, we …

Advocating For Transitional Programs For Adolescents With Idd And Asd, Gabriel D. Moore

Occupational Therapy Doctoral Capstones

This capstone project aimed to empower HIPsters at My Possibilities, a higher education and transitional program located in Plano, TX. Specifically, this project equipped individuals diagnosed with intellectual developmental disability (IDD) and autism spectrum disorder (ASD) with the essential components required to effectively advocate for themselves. Due to the unique challenges this population faces, these components were subjective, allowing for receptivity and class engagement, over the course of 6 weeks. These subjective components developed were Communication, Knowing Yourself, Knowing Your Rights, Goal Making, Initiative, Problem-Solving, Handling Adversity, Managing Emotions, Selflessness, Leadership, and Teamwork. Upon completion of the course, HIPsters reported …

Administration Plan For Use Of Hippotherapy In Occupational Therapy, Ryanna Blake

Occupational Therapy Doctoral Capstones

The intention of this capstone experience was to promote the use of hippotherapy as a treatment strategy in the occupational therapy profession from an administrative and educational standpoint. Hundreds of research studies have indicated the effectiveness of hippotherapy for a variety of ages and diagnoses. However, there are still barriers that prevent hippotherapy from being more accessible and well-known, both by practitioners, client families, and the community. The project was executed at a startup psychotherapy clinic preparing to offer equine-assisted services in Tulsa, Oklahoma. The mutually beneficial partnership led to the creation of a generalized administration plan for an occupational …

Educational Program To Prevent Long-Term Complications For Individuals With Diabetes, Emily M. Ware

Occupational Therapy Doctoral Capstones

This doctoral capstone project aimed to create an educational program to improve quality of life for individuals with diabetes by enhancing daily self-management and occupational engagement to prevent long-term complications. The literature states that although diabetes complications are common, they are also highly preventable through self-management strategies. Because diabetes self-management is deeply embedded into daily routines, occupational therapy practitioners can play a unique role in supporting individuals in this process. Prior to participation in the educational program, participants completed a screening tool assessing their diabetes management routines and confidence in the context of daily activities. An occupational therapy-informed, six-week educational …

Education And Advocacy For Implementation Of Biofeedback Therapy In Pediatrics With Anxiety And Migraine Headaches, Mckenly Roberts

Occupational Therapy Doctoral Capstones

This capstone project explores the implementation of biofeedback therapy in occupational therapy for treating pediatric migraines and anxiety. A comprehensive literature review was conducted, examining peer-reviewed articles from 2000–2024, which revealed biofeedback therapy’s efficacy in addressing stress-related symptoms across age groups. The study focuses on adolescents’ academic and extracurricular occupations, where stress significantly impacts mental and physical health. The project aims to establish a biofeedback therapy program at the Abilene Christian University Psychology Clinic, addressing gaps in current literature and practice guidelines. Utilizing the Person-Environment-Occupation-Performance (PEOP) model, the research highlights biofeedback’s potential to improve functional performance and participation for children …

Program Development And Administration Of Experiential Learning Practices In Ot Education, Elizabeth Ann Marie Beeman

Occupational Therapy Doctoral Capstones

Experiential learning opportunities enhance occupational therapy students’ clinical skills, confidence, and professional preparation through hands-on practice. This capstone project focused on program development and administration at Abilene Christian University’s occupational therapy department. Initially centered on establishing a student-run campus clinic, the project pivoted during week one when needs assessment revealed the clinic concept no longer aligned with departmental and university strategic goals. The revised focus incorporated experiential learning theory and interprofessional education. Over 14 weeks, I conducted nine faculty interviews and four student focus groups. Findings indicated unanimous support for mandatory, scheduled experiential learning opportunities while identifying common implementation barriers, …

2025 December 1 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

An Analysis Of Face Synthesis Methods And Their Influence On Human Perception, Maha Habib Almaimani

All Dissertations

Synthetic faces (e.g., computer-generated characters) have been increasingly utilized across various fields, including entertainment, healthcare, and education. Perceptual studies are often conducted to understand how synthetic faces are perceived by humans, aiming to enhance both quality and user experience in these domains. Over the years, numerous methods have been developed to create synthetic faces, ranging from traditional techniques such as image composites, Active Appearance Models, and 3D Morphable Models to more recent machine-learning-based frameworks like Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs).

Despite the growing adoption of synthetic face generation and the variety of algorithms available for their creation, …

Gender And Consensus On The Courts, Kaleigh A. Ruiz

Michigan Journal of Gender & Law

During group deliberation, women tend to be the harbingers of compromise, vying for consensus on even the most contentious topics. However, women cannot succeed in this endeavor if gender bias prevents their voices from being heard. In federal courts, collaboration is essential to reaching the simple majority needed to resolve a case. While the courts already function under norms of collegiality during deliberations, the practice of writing a separate opinion to acknowledge disagreement with a majority opinion remains relatively common. In this Article, I test two competing theories as to the effects of women judges on consensus. On one hand, …

Authoring Culture: The Foundations Of Twenty-First Century Writing Suggested Assignment, Columbia College Chicago

Authoring Culture: Foundations of Twenty-First Century Writing

A suggested classroom assignment to accompany the Genre and Ethos chapters in Authoring Culture: Foundations of Twenty-First Century Writing .

Response: Foreign Affairs Prosecutions And Cybercrime, Mailyn Fidler

Law Faculty Scholarship

A response to Professor Steven Koh's new article on how the U.S. makes global criminal justice policy. Prof. Fidler examines what a decade of cybercrime indictments reveals about America's approach to prosecuting foreign hackers. Three things stand out: * Beyond Attribution - These indictments aren't just about naming and shaming, or about the typical dimensions of criminal alw. They're sophisticated foreign policy tools that coordinate and moderate international sanctions and global norms. * Intertwined with Cooperation - The indictments alternately create space for and slow the tempo of international cooperation on this issue, according to U.S. interests. * Power Projection …

From Static Prediction To Mindful Machines: A Paradigm Shift In Distributed Ai Systems, Rao Mikkilineni, W. Patrick Kelly

Barowsky School of Business | Faculty Scholarship

A special class of complex adaptive systems—biological and social—thrive not by passively accumulating patterns, but by engineering coherence, i.e., the deliberate alignment of prior knowledge, real-time updates, and teleonomic purposes. By contrast, today’s AI stacks—Large Language Models (LLMs) wrapped in agentic toolchains—remain rooted in a Turing-paradigm architecture: statistical world models (opaque weights) bolted onto brittle, imperative workflows. They excel at pattern completion, but they externalize governance, memory, and purpose, thereby accumulating coherence debt—a structural fragility manifested as hallucinations, shallow and siloed memory, ad hoc guardrails, and costly human oversight. The shortcoming of current AI relative to human-like intelligence is therefore …

Full Issue, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Privacy Rights: Their Evolution, Expansion, And Narrowing, Rebecca Nichole Ivans

Undergraduate Honors Capstone Projects

Privacy rights in the United States have evolved significantly through judicial interpretation, with reproductive rights playing a central role in their expansion and contraction. This paper examines how the Supreme Court's treatment of reproductive rights has shaped the broader understanding of constitutional privacy rights, focusing on landmark cases from Griswold v. Connecticut (1965) to Dobbs v. Jackson Women's Health Organization (2022).

The analysis begins by exploring how the Court first established privacy rights through "penumbras" found within various constitutional amendments, particularly in Griswold's protection of contraceptive access for married couples. The paper traces the expansion of these rights through subsequent …

Role Of Competition In Avoiding Social Collapse, Gabriel M. Tonks

All Graduate Reports and Creative Projects, Fall 2023 to Present

Historical examples suggest that isolated, resource-scarce societies are prone to increased hostility and social disasters. The research in this report explores the role of intrasocietal competition in avoiding resource collapse. Two resource-consumer models are proposed with competition which depends on the level of available resources. One of these models is selected for in-depth analysis, and the region in the parameter space where saddle-node bifurcations emerge is computed numerically. The effects of environmental noise on resource growth are simulated, showing that the increased noise usually has negative long-term effects which might be mitigated via increased consumer competition.

A Persistent Homology Framework For Scrna-Seq: Assessing Clustering Robustness And Quantifying Preprocessing And Integration Effects On Topological Features., Jonah Daneshmand

Electronic Theses and Dissertations

As single-cell RNA sequencing (scRNA-seq) data expands, robust methods for integrating diverse datasets are critical. This dissertation applies Persistent Homology (PH), a technique from Topological Data Analysis (TDA), to a collection of scRNA-seq datasets spanning eight tissue types to quantify how data integration affects topological features and biological interpretability. We assessed global topological structure using Betti curves, Euler characteristics, and persistence landscapes across raw, normalized, and integrated data representations. Our analysis revealed a performance inversion: while conventional methods excelled on unintegrated data, high-granularity topological methods, particularly those sensitive to global data structure, became superior after integration. This suggests a synergy …

Increasing Histidyl Dipeptides In Skeletal Muscle Preserves Muscle Mass And Function In Heart Failure., Mamata Hiraman Chaudhari

Electronic Theses and Dissertations

Introduction: Heart failure is a systemic disease associated with multiple comorbidities, such as skeletal muscle wasting and cardiopulmonary disease. Muscle wasting in heart failure patients is a severe comorbidity associated with decreased exercise capacity and poor quality of life. Previous reports show that oxidative stress is increased in the skeletal muscle of heart failure patients, which can directly lead to muscle wasting. However, antioxidant intervention in these patients was unable to improve cardiac function and consequently had no effect on muscle wasting. Although oxidative stress is the primary driver of skeletal muscle atrophy, no attempt has been made to examine …

The Autonomic And Arrhythmogenic Effects Of Gestational E-Cigarette Exposure., Brittany Rachelle Reynolds

Electronic Theses and Dissertations

Introduction. E-cigarettes (e-cigs) have been shown to be pro-arrhythmic in both human and male rodent studies; however, little is known about how e-cig use impacts patients with a predisposed heightened risk for arrhythmias, including pregnant women. Both pregnancy and e-cig use have independently been shown to increase heart rate, diminish heart rate variability, and increase ventricular premature beats, which is suspected to be due to sympathetic dominance. Importantly, β-blockers have been shown to reduce sympathetic activity, reduce heart rate, increase HRV, and reduce arrhythmias. Thus, the use of β-blockers may help prevent adverse health effects driven by sympathetic dominance from …

Explainable A.I. For Analysis And Interpretation Of Heterogeneous Crime Data., Sadaf Ahmed

Electronic Theses and Dissertations

This dissertation examines the problem of fragmented data in the context of crime and cybercrime analysis. While both domains generate substantial public data, these sources vary widely in format, structure, and coverage, making it difficult to perform consistent inference or develop reliable predictive models. To address these limitations, this work proposes a layered integration framework grounded in ontology-driven modeling and data fusion. The approach is applied to two distinct but related case studies, each focused on constructing a coherent representation of criminal activity from heterogeneous sources. The first case study explores the integration of drug and human trafficking data from …

Summary Of Pine Valley Area Groundwater Studies, Melissa Stamp, Bethany Neilson, Anna Mcentire, Burdette Barker, Lisa Welsh, Joanna Endter-Wada, Brian Steed

Reports

The Utah Division of Water Resources contracted with Utah State University to document key scientific and policy information related to the current water conflict between Iron and Beaver Counties over the development of the Pine Valley Water Supply Project (PVWSP). The proposed PVWSP would pump groundwater from Pine Valley in Beaver County and pipe it southeast to the Cedar City region of Iron County served by the Central Iron County Water Conservancy District (CICWCD). Numerous concerns about the project have been raised by Beaver County and other interested parties. A number of these concerns are related to different understandings or …

The Sexual Objectification Experiences Of Amab Non-Binary People, Lee Rosemary Pradell

All Graduate Theses and Dissertations, Fall 2023 to Present

The current study combines two narrative-based methods to understand how AMAB non-binary people experience sexual objectification. Sexual objectification is the process of being treated as an object instead of as a whole person while also being sexualized. Individual people can sexually objectify others (i.e., catcalling, asking “What gender are you really?”, repeatedly asking female people about when they’re giving birth); institutions and systems can also objectify people (i.e., listing sex on driver’s licenses instead of gender; providing binary bathrooms, sports teams, and schooling; labeling female reproductive care “women’s health”).

The current study employed a process chart task that guided participants …

Fast Computation Of The Friction Stir Welding Process With Model Order Reduction, Joshua Kay

All Graduate Theses and Dissertations, Fall 2023 to Present

Friction stir welding (FSW) is a manufacturing process used to join materials through intense heat and pressure. To better understand and optimize this FSW process, mathematical models incorporating non-Newtonian Navier-stokes equations for large plastic deformation and heat equation for the heat transfer are used to simulate the FSW process. However, solving these coupled and nonlinear equations with high accuracy requires significant computational power and time. This thesis has applied model order reduction, more precisely the Proper Orthogonal Decomposition (POD) and Discrete Empirical Interpolation Method (DEIM), to efficiently solve the FSW system in low-dimensional space. Slight modifications are made regarding the …

Examing Fear Conditioning/Extinction And The Role Of The Amygdala In Human Neuroimaging., Olivia Cook

Electronic Theses and Dissertations

Fear plays a crucial role in survival but can lead to psychological disorders when dysregulated. Fears can be innate due to evolutionary relevance or learned through associative processes, where predictive accuracy of threat is pivotal. Disruptions in fear neurocircuitry contribute to anxiety disorders, characterized by heightened activation and impaired learning. Fear conditioning and extinction paradigms based on classical Pavlovian conditioning have been used to study mechanisms underlying fear learning. Using this experimental model, fear networks in rodents have been described in detail with clear distinction between conditioning and extinction neural functioning. Yet, there is no consensus on the neurobiological processes …

Nonlinear Phase Space Analysis For Anomaly Detection In Ros 2 Communications: Detecting Man-In-The-Middle Attacks In Simulated Environments, William L. Locklier

Graduate Theses and Dissertations (2019 - present)

Robot Operating System 2 (ROS 2) marks a significant advancement over its predecessor through the transition from a centralized to a decentralized architecture, integrating the Data Distribution Service (DDS) to support real-time, scalable communications. Despite these improvements, inherent vulnerabilities in the ROS 2 communication stack continue to leave these systems exposed to sophisticated network-based attacks. This study leveraged nonlinear phase space analysis (NLPSA) as an intrusion detection system (IDS) to detect man-in-the-middle (MitM) attack anomalies in ROS 2 traffic. Grounded in Takens’ embedding theorem, NLPSA reconstructs the phase space of communication features and compares the resulting structure against a baseline …

Experiences Of Research Administrators With Faculty Researchers In Sponsored Project Compliance., Adrienne M. Lindsay

Electronic Theses and Dissertations

The purpose of this study was to examine how central office research administrators perceive and describe their professional interactions with faculty researchers, and how those relationships may impact compliance with sponsored project requirements in United States higher education institutions. Cohen et al.’s (1972) organized anarchy theory and Schein’s (2010) organizational culture theory provided a foundational context for understanding research systems within higher education institutions and the social environment in which research administrators navigate potentially contentious roles, both facilitating research and stewarding compliance for the institution and the sponsor. Findings emerged around specific challenges faced by research administrators, which included role …

A Multilevel Analysis To Evaluate Variability In Sdoh Clusters Within Rurality And Its Effects On Cancer-Specific And All-Cause Mortality In The Us., Stephie Ann Abraham

Electronic Theses and Dissertations

Social determinants of health (SDOH) factors have consistently been shown to impact all-cause and cancer-specific mortality. Area-level SDOH factors that coexist to form “high-risk” clusters are more prevalent in rural than urban areas. However, heterogeneity within rural and urban areas may contribute to variations in SDOH factors that could influence higher mortality rates and is not considered in other studies. The primary objective of this study was to utilize ecological and individual-level data to determine if the composition of SDOH clusters within counties in the rural-urban continuum contributes to differences in all-cause (AC) and cancer-specific mortality rates of lung and …

Perceived Organizational Support Of High-Performance Support Staff Members In Professional Soccer Organizations., Erica B. Thompson

Electronic Theses and Dissertations

The purpose of this study was to explore perceived organizational support among high-performance support staff (HPSS) within professional soccer organizations. Specifically, this study examined how HPSS define organizational support, identified factors that shape their perceptions, explored organizational challenges they experience, and analyzed how those challenges intersect with their perceptions of support. Organizational Support Theory (OST) and its central construct, Perceived Organizational Support (POS), served as the theoretical framework guiding this study. OST assumes employees form global beliefs about the extent to which their organization values their contributions and cares about their well-being. To address the study’s purpose, a basic interpretive …