Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (6086)
- Social and Behavioral Sciences (5030)
- Physical Sciences and Mathematics (3852)
- Law (3788)
- Education (3201)
-
- Arts and Humanities (3140)
- Engineering (2998)
- Life Sciences (2729)
- Medical Specialties (2108)
- Business (1910)
- Medical Sciences (1726)
- Computer Sciences (1634)
- Psychology (1394)
- Accounting (973)
- Taxation (870)
- Nursing (792)
- Sociology (749)
- Public Health (714)
- History (666)
- Higher Education (664)
- Artificial Intelligence and Robotics (646)
- Public Affairs, Public Policy and Public Administration (644)
- Religion (616)
- Computer Engineering (603)
- Biomedical Informatics (580)
- Bioinformatics (571)
- Oncology (568)
- Electrical and Computer Engineering (560)
- Constitutional Law (537)
- Environmental Sciences (534)
- Institution
-
- The Texas Medical Center Library (1512)
- University of Mississippi (1032)
- University of Texas at Arlington (987)
- Walden University (821)
- Liberty University (699)
-
- University of Montana (639)
- Utah State University (506)
- Singapore Management University (487)
- Villanova University Charles Widger School of Law (473)
- University of Kentucky (419)
- University of Arkansas, Fayetteville (414)
- Brigham Young University (405)
- Washington University School of Medicine (403)
- University of Plymouth (399)
- Old Dominion University (381)
- City University of New York (CUNY) (380)
- San Jose State University (379)
- University of Central Florida (374)
- Thomas Jefferson University (367)
- University of New Mexico (366)
- University of South Carolina (363)
- New Jersey Institute of Technology (354)
- Technical Disclosure Commons (348)
- University of New Hampshire (336)
- University of Texas Rio Grande Valley (336)
- Edith Cowan University (332)
- University of South Florida (329)
- Portland State University (312)
- University of Nebraska - Lincoln (309)
- California Polytechnic State University, San Luis Obispo (307)
- Keyword
-
- Humans (1384)
- Female (903)
- Male (862)
- Middle Aged (479)
- Animals (469)
-
- Adult (466)
- Machine learning (403)
- Aged (376)
- Artificial intelligence (364)
- Mice (337)
- ICTS (Institute of Clinical and Translational Sciences) (328)
- Taxation -- Law and legislation -- United States (292)
- Machine Learning (290)
- Education (281)
- Deep learning (228)
- Artificial Intelligence (222)
- Undergraduate (186)
- AI (184)
- Adolescent (175)
- Computer Science (173)
- Mental health (173)
- Child (169)
- COVID-19 (163)
- Young Adult (150)
- United States (149)
- Biomarkers (140)
- Higher education (137)
- Communication (127)
- Deep Learning (125)
- Mice, Inbred C57BL (123)
- Publication
-
- Theses and Dissertations (1238)
- Tax Adviser (862)
- Faculty, Staff and Student Publications (780)
- Walden Dissertations and Doctoral Studies (777)
- Faculty, Staff and Students Publications (571)
-
- Doctoral Dissertations and Projects (498)
- University of Montana Course Syllabi, 2021-2025 (460)
- 2025 Decisions (443)
- 2020-Current year OA Pubs (393)
- Electronic Theses and Dissertations (383)
- Faculty Publications (363)
- Theses (360)
- Defensive Publications Series (347)
- The Shorthorn Newspaper Collection: 1970s (339)
- Research Collection School Of Computing and Information Systems (323)
- Dissertations (318)
- Research outputs 2022 to 2026 (296)
- Faculty Scholarship (278)
- Honors Theses (271)
- Master's Theses (220)
- Neutrosophic Sets and Systems (215)
- Graduate Thesis and Dissertation post-2024 (204)
- Masters Theses (188)
- Graduate Theses and Dissertations (154)
- Indian Journal of Health Sciences and Biomedical Research KLEU (154)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (149)
- Articles (148)
- Hannah Arendt Marginalia - All (143)
- IASDR Conference Series (141)
- Maine Law Review (137)
- Publication Type
Articles 1861 - 1890 of 38884
Full-Text Articles in Entire DC Network
Demystifying The Plea Process: Investigating Attorney Communications And Client Misconceptions, M. M. Wilford, R. J. Difava, K. S. Henderson
Demystifying The Plea Process: Investigating Attorney Communications And Client Misconceptions, M. M. Wilford, R. J. Difava, K. S. Henderson
Criminology and Criminal Justice Faculty Publications and Presentations
Objective: to study issues related to the lawyer and client interaction regarding building a legal position on the case and the plea process.Methods: the article uses the universal dialectical method of cognition, as well as general (analysis, synthesis, induction, deduction) and specific scientific research methods (formal-legal method).Results: As the United States has shifted to “a system of pleas,” the role of defense attorneys has swung from trial litigator to plea negotiator. The study results indicated that defense attorneys spend a significant amount of time meeting with clients. Attorneys also cited substantial deficits in criminal defendants’ knowledge of the legal system, …
Holistic Approaches To Lyme Disease Symptom Management, Leah Van Antwerp
Holistic Approaches To Lyme Disease Symptom Management, Leah Van Antwerp
Honors Theses
Lyme disease is a multisystem tick-borne infection that can lead to long-lasting symptoms even after standard antibiotic therapy, with Lyme arthritis being one of the most common and persistent complications. Due to limited research on this issue, rheumatoid arthritis (RA) will be discussed as a reference for understanding treatment options because it is a similar condition. Since many people continue to experience debilitating pain and reduced quality of life after treatment for Lyme disease, holistic approaches have become increasingly popular for symptom management. This literature review examines three holistic modalities-yoga, acupuncture, and diet modifications- and their effectiveness in alleviating arthritic …
Effective Strategies To Attract And Retain Qualified Hospitality Staff In The Post-Pandemic Caribbean, Rajan Bhattarai
Effective Strategies To Attract And Retain Qualified Hospitality Staff In The Post-Pandemic Caribbean, Rajan Bhattarai
Walden Dissertations and Doctoral Studies
Employee attraction and retention remain critical constraints for Caribbean luxury-wellness resorts in the post-pandemic era. Hospitality and tourism leaders are concerned because persistent vacancy, churn, and extended time-to-competence impair service quality and performance of their organizations. Grounded in the Baldrige Excellence Framework and social exchange theory, the purpose of this qualitative single case study was to explore the effective strategies employed by tourism leaders to attract and retain qualified staff within a Caribbean hospitality organization. Data were collected from five Caribbean leaders (HR director, department manager, and supervisors) using semistructured interviews and analyzing organizational documents. Thematic analysis was used to …
The Impact Of Artificial Intelligence On Employee Attrition And Organizational Profitability, Saeed Almehairi
The Impact Of Artificial Intelligence On Employee Attrition And Organizational Profitability, Saeed Almehairi
Theses
Artificial Intelligence (AI) has become a transformative force in the modern workplace, reshap- ing decision-making processes, enhancing operational efficiency, and influencing the dynamics of human resource management. One of the critical areas where AI demonstrates substantial potential is in predicting, managing, and mitigating employee attrition. Employee attrition remains a pressing organizational challenge, incurring substantial costs in recruitment, training, and lost productivity. This research investigates the dual impact of AI on employee attrition and organizational profitability, exploring both the opportunities and the challenges that arise from its integration into human resource and business operations. The study examines how AI-driven predictive analytics …
Patient-Centered Televisit For Chronic Obstructive Pulmonary Disease Discharge Transitions: User-Centered Design Study, Joanna Abraham, Alicia Meng, Nicolas Caravelli, Leah Traeger, May Nguyen, Vineet Arora, Valerie G Press
Patient-Centered Televisit For Chronic Obstructive Pulmonary Disease Discharge Transitions: User-Centered Design Study, Joanna Abraham, Alicia Meng, Nicolas Caravelli, Leah Traeger, May Nguyen, Vineet Arora, Valerie G Press
2020-Current year OA Pubs
BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects approximately 16 million Americans and often results in avoidable readmissions due, in part, to medication errors and lack of education. Telehealth interventions can support medication reconciliation and inhaler education following hospital discharge for patients with COPD.
OBJECTIVE: This study aimed to design and prototype TELE-TOC (Telehealth Education: Leveraging Electronic Transitions of Care), a post-discharge, in-home, televisit intervention, and to map its workflow to ensure integration into the routine discharge care transition process for patients with COPD.
METHODS: A user-centered design approach across 3 phases was followed to develop and prototype TELE-TOC. Participants included …
Gambling Behaviors, Perceptions, And Risks Among Nevada Adults, Andrea Dassopoulos
Gambling Behaviors, Perceptions, And Risks Among Nevada Adults, Andrea Dassopoulos
International Gaming Institute Faculty Research
This study presents a statewide assessment of gambling behaviors, perceptions, and gambling-related risk among 1,078 Nevada adults. Using a mixed-source, population-calibrated survey developed by UNLV and NORC, the research measures gambling participation, motivations, venue exposure, and attitudes toward harm, treatment, and regulation. The Problem Gambling Severity Index (PGSI) identifies substantial levels of harm: nearly half of past-year gamblers show some degree of risk, with the highest rates among younger adults, racially diverse groups, gaming and hospitality workers, and those who gamble in neighborhood bars or slot parlors. The survey also documents public beliefs about gambling addiction, youth exposure, stigma, and …
Reimagining Pediatric Care: The Future Of Telehealth, Mike Smith, Morgan Waller
Reimagining Pediatric Care: The Future Of Telehealth, Mike Smith, Morgan Waller
Pediatrics in Practice: A CME Podcast
Telehealth has transformed the way families access pediatric care, offering convenience without compromising quality. In this episode, we sit down with Morgan Waller, Director of Telemedicine at Children’s Mercy, to explore the latest advancements in pediatric telehealth. From innovative technologies to strategies for improving access in rural communities, we discuss how virtual care is shaping the future of pediatrics and what it means for families and providers alike.
Click here to stream the podcast episode.
Welcoming Spaces: Parent Leadership And Early Literacy As Community-Based Co-Regulation Supports, Lauren S. Dake
Welcoming Spaces: Parent Leadership And Early Literacy As Community-Based Co-Regulation Supports, Lauren S. Dake
Masters Projects
Many young children exhibit challenging behavior in early childhood settings, often as a response to high levels of stress in their home and community environments. This applied master’s project presents Welcoming Spaces, a parent-led initiative developed to support children’s emotional development, caregiver well-being, and early literacy through informal, community-based experiences. In response to concerns about rising dysregulation and reduced access to supportive environments, the project offers portable play areas hosted by parents at events such as school functions, library gatherings, and local festivals. These spaces include calming sensory activities and opportunities for shared reading, while also providing caregivers with …
2024 Child Fatality Annual Report, Tennessee. Department Of Health.
2024 Child Fatality Annual Report, Tennessee. Department Of Health.
Child Fatalities in Tennessee Report
No abstract provided.
Evaluating Remotely Sensed Spectral Indices To Quantify Seagrass In Support Of Ecosystem-Based Fisheries Management In A Marine Protected Area Of Western Australia, Nick Konzewitsch, Lara Mist, Scott N. Evans
Evaluating Remotely Sensed Spectral Indices To Quantify Seagrass In Support Of Ecosystem-Based Fisheries Management In A Marine Protected Area Of Western Australia, Nick Konzewitsch, Lara Mist, Scott N. Evans
Fisheries Research Articles
Highlights
What are the main findings?- Four spectral indices were identified as important for the quantification of seagrass within and adjacent to the MSC-certified Western Australia Enhanced Greenlip Abalone Fishery. The Normalised Difference Aquatic Vegetation Index (NDAVI) and Depth Invariant Index of the blue and green bands were the most important indices.
- Similar seagrass cover and distribution were observed inside and outside of the fishery area of operation.
- The use of indices from free satellite products via Google Earth Engine workflows and automatic image annotation provides a rapidly repeatable method to support …
U-Glide Program Fall 2025, Unf Office Of Undergraduate Research, Unf Graduate School
U-Glide Program Fall 2025, Unf Office Of Undergraduate Research, Unf Graduate School
Undergraduate – Graduate Learning, Inquiry, and Distinctive Experimentation (U-GLIDE) Symposium Programs
No abstract provided.
Heart-Centered Discernment In Leadership: Pope Francis’S Teachings In Dilexit Nos, Jessica Christie Ludescher Imanaka
Heart-Centered Discernment In Leadership: Pope Francis’S Teachings In Dilexit Nos, Jessica Christie Ludescher Imanaka
Journal of Management for Global Sustainability
This paper articulates the central teachings of Pope Francis’s final encyclical, Dilexit Nos, and explains how these teachings can guide business leadership. Dilexit Nos offers spiritual guidance “on the human and divine love of the Heart of Jesus Christ.” This spiritual encyclical concludes with a reminder about the importance of the love of Christ for the work to which the social encyclicals Laudato Si’ and Fratelli Tutti call us. Pope Leo XIV recently clarified the import of Dilexit Nos for our love for the poor in an apostolic exhortation, Dilexi Te, which Francis had been writing prior to his death. …
The Power Of Positive Lesbian Representation In Television: How It Affects The Well-Being And Identity Formation Of Lgbtq+ Adults, Brittany Berry
The Power Of Positive Lesbian Representation In Television: How It Affects The Well-Being And Identity Formation Of Lgbtq+ Adults, Brittany Berry
University Honors Theses
To date, there are no studies which explore the effects that positively represented Black and lesbian characters in television have on LGBTQ viewers. Exposure to LGBTQ characters has the potential to validate LGBTQ identities and improve well-being. A comprehensive literature review and quantitative analysis using Żerebecki et. al.'s codebook reveals there are simply not enough characters depicted to provide such research. In an attempt to demonstrate the qualities possessed by positively portrayed Black, lesbian characters, this study analyses Taissa Turner from the hit series Yellowjackets available on the streaming network Paramount+.
Outcomes After Ulnar Collateral Ligament Reconstruction And Repair In Nonthrowing Athletes, William L. Johns, Neel K. Patel, Benjamin Miltenberg, Ryan W. Paul, Adeeb J. Hanna, Michael C. Ciccotti, Steven B. Cohen, Michael G. Ciccotti, Christopher C. Dodson
Outcomes After Ulnar Collateral Ligament Reconstruction And Repair In Nonthrowing Athletes, William L. Johns, Neel K. Patel, Benjamin Miltenberg, Ryan W. Paul, Adeeb J. Hanna, Michael C. Ciccotti, Steven B. Cohen, Michael G. Ciccotti, Christopher C. Dodson
Rothman Institute Papers
BACKGROUND: Surgical management of ulnar collateral ligament (UCL) tears in nonthrowing athletes is less commonly performed, and the outcomes of that management have not been thoroughly described.
PURPOSE: To describe the clinical outcomes of surgical management of UCL injury in nonthrowing athletes.
STUDY DESIGN: Case series; Level of evidence, 4.
METHODS: A retrospective review was conducted on all patients who underwent UCL reconstruction or repair across a 10-year period (2010-2020), with nonthrowing athletes who had >2-year follow-up being specifically identified. Demographic variables such as age, sport participation, concomitant procedures, and graft type, as well as postoperative outcomes such as complications, …
Critically Thinking Through A Multiple-Patient Simulation: Applying Real World Principles, Danielle E. Ely, Becky Fights, Allison Johnson, Rachelle Fuller, Karrie Osborne, Jane Milleman, Pamela K. Brelage
Critically Thinking Through A Multiple-Patient Simulation: Applying Real World Principles, Danielle E. Ely, Becky Fights, Allison Johnson, Rachelle Fuller, Karrie Osborne, Jane Milleman, Pamela K. Brelage
Biennial Convention (CONV)
Background Simulating multiple-patient care scenarios enables nursing students to put prioritization and time-management into practice prior to working as registered nurses in the healthcare environment. This project aimed to implement and evaluate a multi-patient simulation.
Method Senior nursing students enrolled in leadership and management experience a multi-patient simulation in which learners are assigned various roles to support four diverse patients. Students exercise autonomy in problem solving as the patient situations unfold around them. Students navigate admissions, transfers, discharges, patient noncompliance, medical complications, and complex family dynamics. After participation, students completed an evaluation of the experience.
Results After approval from the …
Early Warning Detection Of Gravitational Waves With Sgnl, Megan Norris
Early Warning Detection Of Gravitational Waves With Sgnl, Megan Norris
Honors Theses
Gravitational waves (GWs) provide a whole new spectrum with which to observe astrophysical events. Multi-messenger observations including GWs are of particular interest, and these are best facilitated by early warning searches of GWs, which are typically aimed at detecting binary neutron star (BNS) mergers. This work provides an introductory overview of gravitational waves and summarizes the origins and basic physical properties of neutron stars and black holes in binary systems, focusing on BNS mergers and the detection of gravitational waves with LIGO using a modeled search. We assess the performance of a new GW search pipeline called SGNL to evaluate …
A Virtual Or In-Person Infrared Spectroscopy Laboratory Activity For The Analysis Of Fibers And Understanding Of Spectral Library Searches, Erika L. Doctor, Alanna L. Lecher
A Virtual Or In-Person Infrared Spectroscopy Laboratory Activity For The Analysis Of Fibers And Understanding Of Spectral Library Searches, Erika L. Doctor, Alanna L. Lecher
Faculty and Staff Publications & Presentations
The COVID-19 pandemic caused a rapid pivot of instruction in higher education from traditionally in-person modes to virtual modes with a need to maintain student learning outcomes, especially in laboratory courses. The next pandemic and other natural disasters cannot be predicted, and there are other reasons such as lack of resources that may inhibit courses from being implemented in-person. This paper provides a laboratory activity that can be completed in-person or with virtual instruction. This laboratory activity provides a novel approach to teaching students about fiber analysis using ATR-FTIR and elucidates the process of spectral analysis with databases. Students use …
A Mouse Model Of Lipoatrophy Reveals Relationships Between Beige Fat Appearance And Female Fertility, Elizabeth S Anaya, William Dion, Pradip K Saha, Aaron R Cox, Evelyn De Groot, Avery A Ahmed, Jessica B Felix, Bokai Zhu, Stephanie A Pangas, Sean M Hartig
A Mouse Model Of Lipoatrophy Reveals Relationships Between Beige Fat Appearance And Female Fertility, Elizabeth S Anaya, William Dion, Pradip K Saha, Aaron R Cox, Evelyn De Groot, Avery A Ahmed, Jessica B Felix, Bokai Zhu, Stephanie A Pangas, Sean M Hartig
Faculty, Staff and Students Publications
White adipose tissue (WAT) performs vital metabolic and endocrine functions, but roles in female reproduction remain understudied and poorly understood. Here, we report that female mice experiencing progressive lipoatrophy after knockout of Ubc9 in adipocytes (Ubc9fKO) displayed disrupted estrous cycles, reduced ovarian reserve, and subfertility. During aging, female Ubc9fKO mice lose subcutaneous WAT more quickly than their male counterparts and weigh less than littermate controls. Subcutaneous WAT excised from female Ubc9fKO mice strongly enriched for thermogenesis genes generally associated with metabolic benefits. Female Ubc9fKO mice exhibited hypermetabolism and accumulated thermogenic, Uncoupling Protein 1-expressing beige fat cells in residual subcutaneous WAT …
Functional Vs Anatomical Cortico-Striatal Connectivity In The Macaque Brain, Wei Tang, Megan E Monko, Zoe Liu, Ana M G Manea, Fernando A Ortega, Damyan Hart, Jason Zhou, Jan Zimmermann, Sarah R Heilbronner
Functional Vs Anatomical Cortico-Striatal Connectivity In The Macaque Brain, Wei Tang, Megan E Monko, Zoe Liu, Ana M G Manea, Fernando A Ortega, Damyan Hart, Jason Zhou, Jan Zimmermann, Sarah R Heilbronner
Faculty, Staff and Students Publications
The cerebral cortex provides the main input to the striatum, constituting the first step in cortico-basal ganglia loops. Decades of careful anatomical tract-tracing research have established the exquisite topography of each cortical region's projection to the striatum in nonhuman primates. In parallel, neuroimaging research has demonstrated the relationship between cortico-striatal resting-state functional connectivity and specific cognitive, behavioral, psychiatric, and neurological states in humans. However, still unclear is the extent to which functional connectivity recapitulates the specific topographies of cortico-striatal anatomical connectivity. Here, we combined datasets of cortico-striatal anatomical and functional connectivity in macaques to determine the degree of overlap between …
Teaching With V.I.S.I.O.N.: A Qualitative Case Study, Abbrissola A. Shull
Teaching With V.I.S.I.O.N.: A Qualitative Case Study, Abbrissola A. Shull
Graduate Theses, Dissertations, and Capstones
This qualitative case study explored how those matriculating through a teacher education program can develop a critical consciousness of K-12 students experiencing homelessness or high mobility using the Teaching with V.I.S.I.O.N workshop model. This acronym stands for V: Value the culture and lived experiences of students reflected in the classroom, I: Implicit Bias Awareness, S: Study scenarios using the equity literacy case analysis approach (Gorski, 2018), I: Increase the diversity of texts provided in the classroom to reflect these experiences, O: On-going reflection regarding current practices and ways to improve using equity literacy (Gorski, 2018), …
What Is The Hospital Pharmaceutical Care? Perceptions And Expectations Of Doctors In Interprofessional Collaboration In 2 Types Of Indonesia Hospitals, Anisyah Achmad, Savvy Augustin Tirta, Titi Annisa Bella, Ratna Kurnia Illahi, Bambang Sidharta, Valentina Yurina, Wara Rejeki
What Is The Hospital Pharmaceutical Care? Perceptions And Expectations Of Doctors In Interprofessional Collaboration In 2 Types Of Indonesia Hospitals, Anisyah Achmad, Savvy Augustin Tirta, Titi Annisa Bella, Ratna Kurnia Illahi, Bambang Sidharta, Valentina Yurina, Wara Rejeki
Pharmacology and Clinical Pharmacy Research
Hospital Pharmaceutical Care (HPC) is the pharmacist’s direct responsibility to aim for patient safety and quality of life. HPC is a means of avoiding medication and human errors. Carrying out a HPC requires a good collaboration between doctors and pharmacists in treatment management. The aim of the research was to determine the relationship between doctors’ perceptions and expectations of clinical pharmacists at HPC. This research is descriptive quantitative observational with a cross-sectional approach. The data were collected using purposive sampling (type A hospital) and total sampling (type C hospital) through interviews using perception and expectations questionnaires on doctors’ to pharmacists …
Pregnancy Intention And Maternal Morbidity In Oklahoma And Mississippi: A Moderation Analysis Of Abortion Restriction Policies, Vicki Johnson
Pregnancy Intention And Maternal Morbidity In Oklahoma And Mississippi: A Moderation Analysis Of Abortion Restriction Policies, Vicki Johnson
Walden Dissertations and Doctoral Studies
More than half of all pregnancies are unintended (mistimed or unwanted), and women with unplanned pregnancies may face economic hardships for families and additional health consequences if they have pre-existing medical conditions. This quantitative study was conducted to examine the relationship between pregnancy intention levels and severe acute maternal morbidity, specifically chorioamnionitis, among women who gave birth in Oklahoma and Mississippi in 2022. Using secondary data (N=1939) from the Pregnancy Risk Assessment Monitoring System Automated Research Files and state-level abortion policy data from the Guttmacher Institute, this study employed Bronfenbrenner’s social ecological model framework to investigate the relationship between pregnancy …
Perceived Effects Of Verbal Orders On In-Patient Medication Reconciliation And Safety: A Multi-Center Cross-Sectional Study, Yahaya Jafaru, Abubakar K. Sahabi, Mohammed M. Sani
Perceived Effects Of Verbal Orders On In-Patient Medication Reconciliation And Safety: A Multi-Center Cross-Sectional Study, Yahaya Jafaru, Abubakar K. Sahabi, Mohammed M. Sani
Pharmacology and Clinical Pharmacy Research
Medication reconciliation presents significant challenges for healthcare professionals, particularly due to communication gaps that contribute to patient safety incidents. The aim of the study was to investigate the perceived effect of verbal orders on in-patient medication reconciliation and safety. The study was a cross-sectional survey with nurse employees of the three tertiary hospitals in Kebbi State, Nigeria as population of the study. The instrument for the data collection was a 21-items researcher-constructed self-administered questionnaire. Chi-square and binomial regression analysis were used in data analysis. Over two-thirds (70.7%) of the respondents reported a negative perceived effect on the patient’s compliance. The …
Crosstalk Between Gut Microbiota And Antihypertensive Drugs: A Systematic Review, Dhiya'ul Haq, Keri Lestari
Crosstalk Between Gut Microbiota And Antihypertensive Drugs: A Systematic Review, Dhiya'ul Haq, Keri Lestari
Pharmacology and Clinical Pharmacy Research
Hypertension is a multifactorial condition characterized by persistently elevated blood pressure. In addition to genetic and environmental factors, recent studies suggest that the gut microbiota contributes to the development of hypertension and modulates the response to antihypertensive therapy. This review aims to summarize the latest knowledge on the bidirectional interaction between gut microbiota and antihypertensive drugs. Original studies published up to May 2025 on this topic were collected from two online databases: PubMed and Scopus. A total of 220 articles were identified, and 9 articles met the inclusion criteria for further discussion. Three of these included articles discussed how gut …
Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt
Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt
Faculty, Staff and Student Publications
Background: FHF (fibroblast growth factor homologous factor) variants associate with arrhythmias. Although FHFs are best characterized as regulators of voltage-gated sodium channel (VGSC) gating, recent studies suggest broader, non-VGSC-related functions, including regulation of Cx43 (connexin 43) gap junctions and hemichannels, mechanisms that have generally been understudied or disregarded.
Methods: We assessed cardiac conduction and cardiomyocyte action potentials in mice with constitutive cardiac-specific Fgf13 ablation (cFgf13KO) while targeting Cx43 gap junctions and hemichannels pharmacologically. We characterized FGF13 regulation of Cx43 abundance and subcellular distribution. With proximity labeling proteomics, we investigated novel candidate mechanisms underlying FGF13 regulation of Cx43. …
Periodontal Precision: Diagnostic Skills And Confidence Of Dentists In Asian Countries In Applying The 2017 Efp/Aap Periodontal Disease Classification- A Cross-Sectional Pilot Study, Kamran Ali, Priti Charde, Daniel Zahra, Ewen Mccoll, Tayeb Al Hadeethi, Nader Hamdan
Periodontal Precision: Diagnostic Skills And Confidence Of Dentists In Asian Countries In Applying The 2017 Efp/Aap Periodontal Disease Classification- A Cross-Sectional Pilot Study, Kamran Ali, Priti Charde, Daniel Zahra, Ewen Mccoll, Tayeb Al Hadeethi, Nader Hamdan
Peninsula Dental School
Background: The classification of periodontal disease published in 2017 by the European Federation of Periodontology (EFP) and American Academy of Periodontology (AAP), provides a framework for diagnosis and treatment. The aim of this study was to evaluate the diagnostic skills and self-perceived confidence of dentists and dental students based in Asian countries in the use of this classification. Methods: A cross-sectional analytic study design was employed. An online questionnaire encompassing four periodontitis cases was used for data collection. A total of 500 participants were invited to provide a diagnosis and rate their confidence for each case. Results: Responses were provided …
Increased Intermembrane Space [Ca2+] Drives Mitochondrial Structural Damage In Cpvt, Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Mark Bannister, Jinxi Wang, Sage Quiggle, Rachel Battershell, Matthew Gorr, Sandor Györke, Bum-Rak Choi, Christopher George, Andriy Belevych, György Csordás, Dmitry Terentyev
Increased Intermembrane Space [Ca2+] Drives Mitochondrial Structural Damage In Cpvt, Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Mark Bannister, Jinxi Wang, Sage Quiggle, Rachel Battershell, Matthew Gorr, Sandor Györke, Bum-Rak Choi, Christopher George, Andriy Belevych, György Csordás, Dmitry Terentyev
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
BACKGROUND: Mitochondrial dysfunction caused by abnormally high RyR2 (ryanodine receptor) activity is a common finding in cardiovascular diseases. Mechanisms linking RyR2 gain of function with mitochondrial remodeling remain elusive. We hypothesized that RyR2 hyperactivity in cardiac disease increases [Ca 2+ ] in the mitochondrial intermembrane space (IMS) and activates the Ca 2+ -sensitive protease calpain, driving remodeling of mitochondrial cristae architecture through cleavage of structural protein OPA1 (optic atrophy protein 1).
METHODS: We generated a highly arrhythmogenic rat model of catecholaminergic polymorphic ventricular tachycardia, induced by RyR2 gain-of-function mutation S2236L(Ser2336Leu)(+/-) . We created a new biosensor to measure IMS-[Ca2+ ] …
Correction: Changes In Aggressive Behaviors Over Time In Children With Adverse Childhood Experiences: Focusing On The Role Of School Connectedness, Sei Young Lee, Mijin Choi
Correction: Changes In Aggressive Behaviors Over Time In Children With Adverse Childhood Experiences: Focusing On The Role Of School Connectedness, Sei Young Lee, Mijin Choi
Faculty Publications
In the original publication (Lee and Choi 2025), Zhang and Mersky (2022) was not cited. The citation has now been inserted in 5.2. Measures, 5.2.1. Adverse Childhood Experiences, Paragraph Three and should read: Parental substance use questions concerned whether mothers or fathers reported having four or more drinks and any of five types of drugs (e.g., cocaine and heroin) or misuse of prescription drugs (e.g., sedatives and tranquilizers) in the past 12 months. Parental incarceration was measured by whether the mother, father, or mother’s current partner had spent any time in prison or jail. Sample questions of parental domestic violence …
Inhibitory Control, Attentional Bias, And Palatable Food Consumption In Adolescents: A Laboratory Feasibility Randomized Controlled Trial., Carolina M. Bejarano, Adrian Ortega, Christopher C. Cushing
Inhibitory Control, Attentional Bias, And Palatable Food Consumption In Adolescents: A Laboratory Feasibility Randomized Controlled Trial., Carolina M. Bejarano, Adrian Ortega, Christopher C. Cushing
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: Understanding relationships among inhibitory control, attentional bias to food cues, and food consumption in nonclinical adolescent samples can inform preventive efforts for disordered eating and associated health risks.
OBJECTIVE: This pilot study conducted preliminary testing of an inhibitory control training intervention on attentional bias toward food cues, hedonic appetite, and food consumption, as well as examined inhibitory control's relationship with hedonic appetite, food consumption, binge eating, and cognitive restraint.
METHODS: Participants (N=43; mean age 15.1, SD 1.7 years; 31/43, 72% female) were randomized to a food cue-specific go/no go inhibitory control training intervention or control group, took part in …