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2025

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How Privilege Affects Reactions To Men's Femininity, Matthew G. Nielson, Brittany Romanello, Alexa Martin-Storey Sep 2025

How Privilege Affects Reactions To Men's Femininity, Matthew G. Nielson, Brittany Romanello, Alexa Martin-Storey

Sociology and Criminology Faculty Publications and Presentations

This research aimed to explore social responses to men's femininity, with particular attention paid to the impact of privilege as detailed in the framework of hybrid masculinities. Generally, men's femininity is met with condemnation, but those with more privilege may have more leeway than those with less. Additionally, cultural attitudes may be evolving to be less homonegative, which may alter the reception of queer men's femininity. From interviews with 30 young adult men in a US Southwestern city, we found evidence for compensatory masculinity privilege - allowing femininity based on other successful enactments of masculinity - and 'gay allowance' - …


Assessment Of Microbial Quality And Safety, Including Aflatoxin B1, In Buckwheat Flour And Groats, La Fontaine Bahatsi Sep 2025

Assessment Of Microbial Quality And Safety, Including Aflatoxin B1, In Buckwheat Flour And Groats, La Fontaine Bahatsi

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Buckwheat (Fagopyrum esculentum), a gluten-free pseudocereal, has gained popularity in global food markets for its nutritional value and functional properties. However, despite its health-promoting potential, buckwheat is vulnerable to microbial contamination and mycotoxin accumulation during cultivation, processing, and storage. These factors present significant food safety concerns that remain understudied, particularly in North America.

This study investigated the microbiological quality and mycotoxin contamination of buckwheat flour and groats collected from different suppliers via online sourcing. Samples were collected in two consecutive years (2024-2025). Microbiological quality, including aerobic plate counts (APC), Enterobacteriaceae, coliforms, E. coli, yeasts, and molds, was evaluated …


The Official List Of The Birds Of Nebraska: 2024, Mark A. Brogie Sep 2025

The Official List Of The Birds Of Nebraska: 2024, Mark A. Brogie

Nebraska Bird Review

The duties of the Nebraska Ornithologists’ Union Records Committee (NOURC 2010) include:

A. The committee shall publish an official list of the birds of Nebraska.
B. The official list will include all those species whose occurrence has been reported in Nebraska (and approved by the NOURC).
C. The committee shall keep the official list current.
D. The committee shall publish a list of species for which details are requested with every sighting reported.

The 2024 NOURC has completed the above-described duties, and the following is a result of its endeavors.

The “Official List of the Birds of Nebraska” was last …


First Confirmed Nebraska Breeding Record Of The Common Raven (Corvus Corax) Since The 19th Century, Eugene A. Huryn, Jacob C. Cooper Sep 2025

First Confirmed Nebraska Breeding Record Of The Common Raven (Corvus Corax) Since The 19th Century, Eugene A. Huryn, Jacob C. Cooper

Nebraska Bird Review

In Nebraska, the Common Raven was likely widespread prior to 1900, being codistributed with the American Bison (Bison bison). Records in this time are spotty, but consistent. Thomas Say reported a nearly fledged brood—the only confirmed breeding record in this period—at Fort Calhoun in Washington County on May 12, 1820. A Common Raven was collected at Fort Randall, on the Missouri River just north of the modern Nebraska–South Dakota border, in the fall of 1857 during the Lieutenant Warren Expeditions. Another specimen, now lost, was collected by J. B. Hasty in 1899 in Arapahoe, Furnas County. Bruner et …


Summer Field Report, June–July 2025, W. Ross Silcock Sep 2025

Summer Field Report, June–July 2025, W. Ross Silcock

Nebraska Bird Review

I have mentioned previously the breeding categories that are available to observers in eBird checklists. This database is becoming more comprehensive and useful, and I encourage observers to use this eBird feature.

Usefulness of Merlin-derived checklists continues to be an issue. As an example, Merlin seems to love White-winged Doves; there were 52 undocumented Merlin reports of this species this summer, no doubt some correctly identified and acceptable if observers had taken a minute to add even minimal observation details to support Merlin’s identifications.

A vexing issue for me is determining the status of midsummer (i.e. between spring and fall …


Kentucky Model Minimum Uniform Crash Criteria (Mmucc) Sixth Edition Report Card, William Staats, Nikiforos Stamatiadis, Eric Green, Nathaniel Swallom Sep 2025

Kentucky Model Minimum Uniform Crash Criteria (Mmucc) Sixth Edition Report Card, William Staats, Nikiforos Stamatiadis, Eric Green, Nathaniel Swallom

Kentucky Transportation Center Research Report

The National Highway Traffic Safety Administration published the Model Minimum Uniform Crash Criteria (6th Edition) (MMUCC) in 2024. This updated version of the MMUCC contains recommendations for improving and standardizing electronic crash data. Its guidelines address the collection and presentation of 105 data elements and 1,056 data attributes. To facilitate a possible redesign of Kentucky’s crash reporting process, Kentucky Transportation Center (KTC) researchers reviewed the updated criteria and evaluated the degree to which the state complies with its recommended methods of gathering, storing, and presenting crash data. At the level of data elements, Kentucky is 25 percent compliant; for data …


Kentucky Traffic Collision Facts Calendar Year 2024 Report, Paul Ross, Eric Green, Christopher Blackden, Kenneth Agent, Christopher Van Dyke Sep 2025

Kentucky Traffic Collision Facts Calendar Year 2024 Report, Paul Ross, Eric Green, Christopher Blackden, Kenneth Agent, Christopher Van Dyke

Kentucky Transportation Center Research Report

No abstract provided.


Khaled Hosseini’S Judgment In The Kite Runner Towards Pashtun And Hazara Identities, Bilal Waziri, Dawod Mangal, Kamaldeen Kamal Sep 2025

Khaled Hosseini’S Judgment In The Kite Runner Towards Pashtun And Hazara Identities, Bilal Waziri, Dawod Mangal, Kamaldeen Kamal

Journal of Research Initiatives

This book review offers a compelling examination of Khaled Hosseini's portrayal of Pashtun and Hazara identities in his acclaimed novel, *The Kite Runner*. Through a literary-ethnographic lens, the research delves into how narrative techniques can construct, amplify, or distort ethnic representations, particularly within the tumultuous backdrop of Afghanistan. The novel is scrutinized for its stark depiction of Pashtuns as oppressors and Hazaras as perennial victims, which risks perpetuating a simplistic and problematic singular narrative. Employing a library-based qualitative approach, this paper thoughtfully interprets textual evidence within the rich sociocultural and historical landscape of Afghanistan. The findings reveal that while the …


September 2025, Office Of Research Sep 2025

September 2025, Office Of Research

Research Update

No abstract provided.


Christian Higher Education (Book Review), Carl P. Fictorie Sep 2025

Christian Higher Education (Book Review), Carl P. Fictorie

Pro Rege

Reviewed Title: Christian Higher Education by Perry L. Glanzer, Theodore F. Cockle, and Jessica Martin. Abilene Christian University Press, 2023. 176 pp. ISBN: 9781684264124.


Who Is The God "With Whom We Have To Do"?, Michael Williams Sep 2025

Who Is The God "With Whom We Have To Do"?, Michael Williams

Pro Rege

No abstract provided.


Fisheries Science Update - Pilbara Demersal Scalefish Resource - September 2025, Department Of Primary Industries And Regional Development, Western Australia Sep 2025

Fisheries Science Update - Pilbara Demersal Scalefish Resource - September 2025, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Science Updates

The Department of Primary Industries and Regional Development (DPIRD) monitors the status of Western Australia’s demersal scalefish resources by undertaking periodic stock assessments on key indicator species.

This summary provides key outcomes of the 2024 assessment of the Pilbara Demersal Scalefish Resource (Fisheries Research Report No. 338).


Tissue Engineered Combinatorial Therapeutics For Spinal Cord Injury Repair, Inha Baek Sep 2025

Tissue Engineered Combinatorial Therapeutics For Spinal Cord Injury Repair, Inha Baek

Graduate Theses and Dissertations

Traumatic spinal cord injury (SCI) lead to temporary or permanent sensorimotor deficit due to the complex and multifaceted features of the injury site, making the treatments ineffective. Recent research emphasizes the potential of combinatorial therapeutics approaches combining different therapeutics, such as biomaterials and stem cell transplantation. In this context, nerve composite hydrogels, fabricated from decellularized sciatic nerve (dSN) and spinal cord (dSC) extracellular matrices (ECM), might be promising platforms due to their biocompatibility and ability to mimic native microenvironments. In this study, we developed and characterized nerve mimetic composite hydrogels embedded with human adipose-derived stem cells (hASCs) and investigated their …


Dual Investigations Into Broiler Health: Mitochondrial Gene Expression In Ascites Susceptibility And G-1,25(Oh)₂D₃-Driven Modulation Of Bone And Gut Integrity In Lameness, Layla Hussein Al-Mitib Sep 2025

Dual Investigations Into Broiler Health: Mitochondrial Gene Expression In Ascites Susceptibility And G-1,25(Oh)₂D₃-Driven Modulation Of Bone And Gut Integrity In Lameness, Layla Hussein Al-Mitib

Graduate Theses and Dissertations

Modern broiler production faces persistent challenges from metabolic and skeletal disorders, particularly ascites and bacterial chondronecrosis with osteomyelitis (BCO), which compromise animal welfare and production efficiency. This dissertation examines two key factors that contribute to these conditions: mitochondrial gene expression associated with pulmonary hypertension syndrome (PHS) and the role of intestinal barrier integrity in mitigating lameness. In the first study, the expression of mitochondrial genes COXII and ATP6 was evaluated in the breast, thigh, and lung tissues of three broiler genetic lines—ascites-susceptible (SUS), ascites-resistant (RES), and unselected relaxed (REL). While no significant expression differences were observed in muscle tissues, SUS …


Sound Decisions: The Impact Of Music Genre In Fashion Advertising On Consumer Perceptions And Purchase Intention, Cassandra Thomas Sep 2025

Sound Decisions: The Impact Of Music Genre In Fashion Advertising On Consumer Perceptions And Purchase Intention, Cassandra Thomas

Graduate Theses and Dissertations

This study examines how music genre, brand type, and the perceived congruency between the two influences consumer perceptions of fashion advertising. Guided by Congruity Theory and Attitude Theory, this study employed a 3x3 experimental design in which 252 participants viewed one of nine advertisement conditions varying by music genre (pop, hip-hop, electronic) and brand type (activewear, fast fashion, luxury). A series of one-way ANOVAs, bivariate correlations, and regression analyses were conducted to interpret the effects of music genre, brand type, and perceived congruency on attitudes toward 1) the advertisement and brand, 2) credibility of the advertisement and brand, and 3) …


Nanoparticle Iron Based Catalysts For Clean Water And Other Applications, Shelby Lynn Foster Sep 2025

Nanoparticle Iron Based Catalysts For Clean Water And Other Applications, Shelby Lynn Foster

Graduate Theses and Dissertations

This dissertation explores the development, characterization, and application of iron-based catalysts for environmental remediation and energy generation. The research focuses on Fe-based nanomaterials for water purification, electrochemical ammonia production, and ethanol oxidation enhancement. The first section of the dissertation investigates the removal of water contaminants using nickel-iron (NiFe) bimetallic nanoparticles. Various NiFe ratios were synthesized and tested for their efficiency in degrading the azo dye (Orange G), with lower Ni content formulations achieving 80–99% dye removal within 60 minutes. Results show that changing the molar ratio of nickel to iron caused different removal rates, as well as the extent of …


Request For Modification 25-031 To The Long-Term Monitoring And Maintenance Plan Of The Mixed Waste Landfill And The Resource Conservation And Recovery Act Facility Operating Permit Renewal Request, Sandia National Laboratories/New Mexico, Epa Id Nm5890110518, Sandia National Laboratories/Nm Snl Sep 2025

Request For Modification 25-031 To The Long-Term Monitoring And Maintenance Plan Of The Mixed Waste Landfill And The Resource Conservation And Recovery Act Facility Operating Permit Renewal Request, Sandia National Laboratories/New Mexico, Epa Id Nm5890110518, Sandia National Laboratories/Nm Snl

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia National Laboratories, New Mexico (SNL/NM) have requested modifications to the Resource Conservation and Recovery Act Facility Operating Permit (Permit) for Sandia National Laboratories/New Mexico. The requested modifications consist of revisions to the Mixed Waste Landfill (MWL) Long-Term Monitoring and Maintenance Plan (LTMMP), which is incorporated by reference into Permit Attachment M, "Long-Term Monitoring and Maintenance Plan for Solid Waste Management Units and Areas of Concern Granted Corrective Action Complete with Controls." The MWL is also known as Solid Waste Management Unit (SWMU) 76.

The DOE/NNSA and SNL/NM propose to update …


Resource Assessment Report No. 02: West Coast Demersal Scalefish Resource 2025 Assessment, Emily A. Fisher, David V. Fairclough, Elaine Lek, Jeremy Briggs, Sybrand Alex Hesp, Ainslie Denham Sep 2025

Resource Assessment Report No. 02: West Coast Demersal Scalefish Resource 2025 Assessment, Emily A. Fisher, David V. Fairclough, Elaine Lek, Jeremy Briggs, Sybrand Alex Hesp, Ainslie Denham

Resource Assessment Reports

The West Coast Demersal Scalefish Resource (WCDSR) comprises over 100 species inhabiting inshore (20-250 m deep) and offshore ( > 250 m deep) waters of the West Coast Bioregion (WCB; north of Kalbarri to east of Augusta). The WCDSR is primarily targeted by commercial, charter and recreational boat-based line fishers, including the commercial West Coast Demersal Scalefish (Interim) Managed Fishery (WCDSIMF). Indicator species selected for monitoring and assessing the status of the inshore suite of the WCDSR include Snapper, WA Dhufish and Baldchin Groper, while indicators for the offshore suite include Hapuku, Bass Groper and Blue-eye Trevalla.

The WCDSR is more …


Horses And The Transition From Feudalism To Capitalism., Thomas E. Lambert Sep 2025

Horses And The Transition From Feudalism To Capitalism., Thomas E. Lambert

Faculty and Staff Scholarship

Many scholarly articles and books have been written about the transition from feudalism to capitalism over the decades. The various points of views on what is the “main driver” or “prime mover” of the transition have been debated in various forums by historians and economic historians with a different major factor being advocated by different proponents or schools of thought. This paper tries to offer another analysis of how the horse could have been an important “means to an end” in the development of capitalism, and this analysis possibly can lead to support for more than one view of what …


Nocturnal Foraging By Great Blue Heron (Ardea Herodias) And Roseate Spoonbill (Platalea Ajaja), Laura E. Josler, Johnny E. Owens, Sarrah E. Bristol, Leo N. Dutkewych, Abigail R. Kauke, Signe E. Renstrom, Ben G. Sheffield, Madelyne E. Vashaw, Avery J. Nesbitt, Melia K. Paat, Timothy D. Bransford, Elizabeth A. Forys Sep 2025

Nocturnal Foraging By Great Blue Heron (Ardea Herodias) And Roseate Spoonbill (Platalea Ajaja), Laura E. Josler, Johnny E. Owens, Sarrah E. Bristol, Leo N. Dutkewych, Abigail R. Kauke, Signe E. Renstrom, Ben G. Sheffield, Madelyne E. Vashaw, Avery J. Nesbitt, Melia K. Paat, Timothy D. Bransford, Elizabeth A. Forys

Florida Field Naturalist

The Great Blue Heron (Ardea herodias) and Roseate Spoonbill (Platalea ajaja) are long-legged wading birds that can forage throughout a 24-hour cycle. Nocturnal foraging enables these species to take advantage of optimal foraging conditions and reduced competition. This study aims to investigate how environmental factors influence the nocturnal foraging behavior of these species. To monitor foraging activity, we deployed 17-18 infrared cameras from dusk until dawn from 4 October 2023 to 24 July 24 2024, covering two sampling periods across different habitats within Fort De Soto County Park, a barrier island complex in Tampa Bay, Florida. We compared the frequency …


Rural Business Development Corporation Annual Report 2024-25, Department Of Primary Industries And Regional Development, Western Australia Sep 2025

Rural Business Development Corporation Annual Report 2024-25, Department Of Primary Industries And Regional Development, Western Australia

All other publications

In this report, the Rural Business Development Corporation is referred to as ‘the Corporation’ or ‘the RBDC’. The RBDC is an independent statutory authority of the Government of Western Australia (WA), established under the Rural Business Development Corporation Act 2000 (Act). The Act preserved and continued the body corporate established by the Rural Adjustment and Finance Corporation Act 1993.

What we do

The RBDC administers approved assistance schemes on behalf of the WA Government for the benefit of rural industry and regional communities. Approved schemes may provide financial assistance by way of loans, grants, or other financial incentives. The Act …


Procedures For Rangeland Condition Assessment In The Kimberley 2025, Department Of Primary Industries And Regional Development, Western Australia Sep 2025

Procedures For Rangeland Condition Assessment In The Kimberley 2025, Department Of Primary Industries And Regional Development, Western Australia

Natural resources published reports

This report defines the procedures used in 2025 by DPIRD to complete rangeland condition assessment (RCA) in the Kimberley region which has grass-based pastures. For the rest of the pastoral estate, DPIRD uses the Procedures for RCA in the Pilbara and southern rangelands which have predominantly shrub pastures.

RCA is the process DPIRD uses to make systematic, station-level assessment of rangeland. Rangeland condition considers both the condition of pastures (as defined in the 'Pasture condition guide for the Kimberley') and soils as determined by erosion, using the erosion assessment method on pastoral lands in Western Australia. The methods have evolved …


Stakeholder Views On Lessons Learned For The Antimicrobial Resistance Panel From Previous International Science Panels [Version 1], Iruka N. Okeke, Ayodele A. Akinyele, Javier Guzman, Kevin Outterson Sep 2025

Stakeholder Views On Lessons Learned For The Antimicrobial Resistance Panel From Previous International Science Panels [Version 1], Iruka N. Okeke, Ayodele A. Akinyele, Javier Guzman, Kevin Outterson

Faculty Scholarship

The United Nations General Assembly called in September 2024 for the establishment of an independent panel for actionable evidence against antimicrobial resistance (IPEA). The task of designing the panel was given to the Quadripartite Joint Secretariat (QJS) on Antimicrobial Resistance (AMR) with a delivery timeline of 15 months. To promote stakeholder thought and input around what this panel should look like and how it should work, which could feed into the QJS’s consultation process, we independently commissioned seven papers to examine lessons that could be learned from other high-level scientific panels. We then called a convening of stakeholders that were …


Peripartum Depression Pharmacotherapies Targeting Gaba-Glutamate Neurotransmission, Alan C Courtes, Louisa Smitherman, Lokesh Shahani, Jair C Soares, Laura Goetzl Sep 2025

Peripartum Depression Pharmacotherapies Targeting Gaba-Glutamate Neurotransmission, Alan C Courtes, Louisa Smitherman, Lokesh Shahani, Jair C Soares, Laura Goetzl

Faculty, Staff and Student Publications

Peripartum depression (PPD) represents a significant public health concern, affecting 10-17% of women globally. Traditional monoaminergic treatments demonstrate limited efficacy and delayed onset of action. The glutamate-GABA imbalance hypothesis provides a novel theoretical framework for understanding depression pathophysiology and developing targeted therapeutic interventions. This review examines emerging pharmacotherapeutic approaches targeting glutamatergic and GABAergic neurotransmitter systems for PPD treatment. Search criteria targeted randomized clinical trials investigating GABA-A-positive allosteric modulators (brexanolone, zuranolone, and ganaxolone) and NMDA receptor antagonists (ketamine and esketamine) in PPD patients. Brexanolone was the first neurosteroid to receive FDA approval for PPD, while zuranolone also shows promise. Ketamine and …


In Situ Programming Of The Tumor Microenvironment To Alleviate Immunosuppression For Pancreatic Cancer Immunotherapy, Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yun Zhang, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y S Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang Sep 2025

In Situ Programming Of The Tumor Microenvironment To Alleviate Immunosuppression For Pancreatic Cancer Immunotherapy, Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yun Zhang, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y S Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang

Faculty, Staff and Student Publications

Recent studies have highlighted the pivotal role of the cGAS‐STING pathway in cancer immunotherapy. However, clinical trials with cGAS‐STING pathway agonists have faced setbacks thanks to their short biological half‐life, lack of tumor specificity, and potential to promote tumor immune evasion. To address these challenges, a novel exosome‐based drug delivery platform, termed cmExoaCD11b is developed, designed to precisely target and reprogram the tumor microenvironment (TME) in situ for pancreatic cancer immunotherapy. cmExoaCD11b is engineered to encapsulate high copy numbers of IL‐12 mRNA and 2′3’‐cGAMP (cGAMP) and is functionalized with CD11b antibodies for targeted delivery to macrophages. Notably, cmExoaCD11b facilitated the …


Analysis Of Hospital Costs For Robotic And Open Pancreatectomy Incurred During The Implementation Of A Robotic Pancreatectomy Program At A Cancer Center, Heather G Lyu, Yuki Hirata, Pamela W Lu, Jess E Maxwell, Rebecca A Snyder, Hop Tran Cao, Matthew H G Katz, Naruhiko Ikoma Sep 2025

Analysis Of Hospital Costs For Robotic And Open Pancreatectomy Incurred During The Implementation Of A Robotic Pancreatectomy Program At A Cancer Center, Heather G Lyu, Yuki Hirata, Pamela W Lu, Jess E Maxwell, Rebecca A Snyder, Hop Tran Cao, Matthew H G Katz, Naruhiko Ikoma

Faculty, Staff and Student Publications

Background: Costs associated with robotic pancreatectomy compared to those of open pancreatectomy are assumed to be high but are not well known, particularly during the initial implementation of the robot.

Study design: Patients who underwent pancreatectomy for any diagnosis from January 2017 to August 2021 were identified retrospectively. Total hospital cost was calculated using intraoperative, inpatient, and outpatient costs within 30 days of surgery. The ratio of the total cost of each pancreatectomy to the average cost of all operations at our center was used to represent cost without sharing proprietary financial data. Propensity score matching was performed to account …


Secretogranin 2 Binds Lilrb4 Resulting In Immunosuppression, Xing Yang, Ryan Huang, Meng Fang, Yubo He, Jingjing Xie, Chengcheng Zhang, Mi Deng, Wei Xiong, Cheryl Lewis, Zade Sadek, Ankit Gupta, Lianqi Chen, Xuewu Zhang, Lei Guo, Lin Xu, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang Sep 2025

Secretogranin 2 Binds Lilrb4 Resulting In Immunosuppression, Xing Yang, Ryan Huang, Meng Fang, Yubo He, Jingjing Xie, Chengcheng Zhang, Mi Deng, Wei Xiong, Cheryl Lewis, Zade Sadek, Ankit Gupta, Lianqi Chen, Xuewu Zhang, Lei Guo, Lin Xu, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang

Faculty, Staff and Student Publications

Immunosuppressive myeloid cells are important in a variety of physiological and pathological contexts, including tumor development, but how hormones might regulate their activity is unclear. Secretogranins, a family of secretory proteins in endocrine and neuronal cells, are proposed to function as prohormones or hormones, but their specific receptors are unknown. Here we show that secretogranin 2 (SCG2), a granin family member, functionally interacts with leukocyte immunoglobulin-like receptor B4 (LILRB4) on monocytic cells. Tumor-derived SCG2 promotes tumor growth in myeloid-specific LILRB4 transgenic mice in a T cell-dependent manner, whereas SCG2 deficiency in host mice impairs tumor progression and reduces infiltration of …


Mechanisms Underlying Treatment-Resistant Depression: Exploring Sex-Based Biological Differences, Francisco E R Da Silva, Atakan Yucel, Antonio P M Menezes, Ana C Ruiz, Marcela C Carbajal Tamez, Giselli Scaini Sep 2025

Mechanisms Underlying Treatment-Resistant Depression: Exploring Sex-Based Biological Differences, Francisco E R Da Silva, Atakan Yucel, Antonio P M Menezes, Ana C Ruiz, Marcela C Carbajal Tamez, Giselli Scaini

Faculty, Staff and Student Publications

Treatment-resistant depression (TRD) represents a severe and complex subtype of major depressive disorder (MDD), affecting approximately 30% of patients who fail to respond adequately to multiple standard antidepressant therapies. While the pathophysiology of TRD remains incompletely understood, emerging evidence suggests that sex-based biological differences might influence its onset, progression, and treatment response. Women are disproportionately affected by depression and are more likely to experience residual symptoms and treatment resistance, potentially due to hormonal fluctuations, immune system differences, and variations in brain circuitry and neuroplasticity. This narrative explores the current literature on the mechanisms underlying TRD, with a particular emphasis on …


Risk Of Second Primary Lung Cancer Among Cancer Survivors Stratified By The Site Of First Primary Cancer And The Lung Cancer Screening Eligibility Status, Sara Nofal, Edwin J Ostrin, Jianjun Zhang, Jia Wu, Paul Scheet, John V Heymach Sep 2025

Risk Of Second Primary Lung Cancer Among Cancer Survivors Stratified By The Site Of First Primary Cancer And The Lung Cancer Screening Eligibility Status, Sara Nofal, Edwin J Ostrin, Jianjun Zhang, Jia Wu, Paul Scheet, John V Heymach

Faculty, Staff and Student Publications

Personal history of cancer is an independent risk factor for developing lung cancer. However, it is not considered in the current US lung cancer screening (LCS) guidelines. In this study, we assessed the risk of developing lung cancer among cancer survivors across 24 different sites of first primary cancer stratified by their LCS eligibility status. Using data from the Patient History Database at the University of Texas MD Anderson Cancer Center, we calculated and compared the cumulative incidence of second primary lung cancer, the overall and the LCS eligibility status-specific, stratified by the site of first primary cancer among cancer …


Polydrug Abuse: Choice Between Drugs As A Function Of Concurrent Nonindependent Ratio Sizes, Richard A Meisch, Thomas H Gomez, Scott D Lane Sep 2025

Polydrug Abuse: Choice Between Drugs As A Function Of Concurrent Nonindependent Ratio Sizes, Richard A Meisch, Thomas H Gomez, Scott D Lane

Faculty, Staff and Student Publications

Polydrug abuse is the persistent self-administration of more than one reinforcing drug. The present study provided rhesus monkeys concurrent access to two drugs: 8% alcohol and solutions of either cocaine or methadone. The liquids were available under concurrent nonindependent fixed-ratio (FR) schedules across increasing and then decreasing ratio sizes. These schedules generate high rates of changeover responses and yield a dependent variable of responses per delivery that is not rigidly tied to the ratio-schedule value. The programmed schedule size was equal for both liquids and increased in the sequence 8, 16, 32, and so on until responding decreased, whereupon the …