Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 2911 - 2940 of 23036

Full-Text Articles in Entire DC Network

Theory Of Mind Across Cultures: Psychological Implications, Lewis Hancock, Simon Dein Nov 2025

Theory Of Mind Across Cultures: Psychological Implications, Lewis Hancock, Simon Dein

Online Readings in Psychology and Culture

Theory of Mind (ToM) refers to a set of social and cognitive abilities that we use to infer and understand other people’s mental states. This paper begins by outlining ToM, its component skills, and what research methods have been used to measure it. It then summarises research on how culture and other social factors such as language, parenting, and socio-economic status can impact its development, in particular differences in age of mastery of various aspects of ToM. Mental disorders characterised by deficits in ToM – in particular ASD – are also discussed and used to elucidate its nature and development. …


Visual Ecologies And Language In Digital Environments: Narratives From First-Year Composition Students In Multimodal Learning, Elizabeth Escobedo Salazar Nov 2025

Visual Ecologies And Language In Digital Environments: Narratives From First-Year Composition Students In Multimodal Learning, Elizabeth Escobedo Salazar

Open Access Theses & Dissertations

The expansion of Information and Communication Technologies (ICTs) developed new perceptions of learning, communication processes, shaped university students' new practices and has brought about significant changes in social dynamics. Images and visual language have become central to the way humans communicate, communication processes have changed, and the composition and creation of arguments have changes. In this context, the use of multiple screens (Multiscreens) has led to multitasking, but additionally in digital contexts where students are hyper-connected. They do their homework while on social media, texting, creating videos, using a new app, or watching a movie on YouTube or Netflix. This …


Ai Companions And The Lessons Of Family Law, Clare Huntington Nov 2025

Ai Companions And The Lessons Of Family Law, Clare Huntington

Faculty Scholarship

Virtual friends and lovers powered by artificial intelligence are rapidly moving to the center of our emotional and social lives. Millions of people turn to AI companions every day for conversation, romance, sexual intimacy, therapy, and education. AI companionship holds promise, potentially reducing loneliness, supporting people without access to mental health treatment, helping students learn, and offering a judgment-free space for sensitive conversations. But AI companionship also raises significant concerns. The technology's addictiveness may exacerbate loneliness and can undermine human relationships. Therapy bots may prove more harmful than helpful. AI companions can be emotionally abusive. And their access to the …


Extremism Governance In The United Arab Emirates: A Case Study Using Qualitative Policy Framework, Haya Saleh Almansoori Nov 2025

Extremism Governance In The United Arab Emirates: A Case Study Using Qualitative Policy Framework, Haya Saleh Almansoori

Theses

This thesis investigates how the United Arab Emirates governs extremism using various models of governance and Gareth Morgan’s metaphorical organizational models. This research goes beyond a focus on security and looks at extremism as a governance and policy problem related to social cohesion, institutional trust, and legitimacy. The research utilizes a qualitative case study design through analyzing federal laws and national strategies, as well as institutional frameworks to understand how authority, coordination and meaning are organized in the UAE’s governance of extremism.

The results show that the UAE’s governance of extremism is characterized as a hybrid governance model with hierarchical …


Comparison Of Alcohol-Induced Hepatoprotective Effects Of The High Fischer Ratio Oligopeptides With/Without Half Substitution By Pueraria Lobata, Yongke Deng, Qin Zhao, Na Chen, Zhiqin Zhang, Jingxuan Wang, Hongbing Fan, Haimei Liu, Lili Zhang Nov 2025

Comparison Of Alcohol-Induced Hepatoprotective Effects Of The High Fischer Ratio Oligopeptides With/Without Half Substitution By Pueraria Lobata, Yongke Deng, Qin Zhao, Na Chen, Zhiqin Zhang, Jingxuan Wang, Hongbing Fan, Haimei Liu, Lili Zhang

Animal and Food Sciences Faculty Publications

Long-term excessive intake of alcohol can cause serious damage to the liver, and the study of natural active ingredients with hepatoprotective effects is of great significance for the prevention and treatment of alcoholic liver injury. This study explored the ameliorative effects of high F-value oligopeptides (HFOPs) from Chlamys farreri, Pueraria lobata extract (PL), and their complex (HFOPs + PL) on alcoholic liver injury. Results showed HFOPs + PL significantly reduced alanine aminotransferase (ALT) and aspartate aminotransferase (AST) leakage, increased superoxide dismutase (SOD) and glutathione (GSH) activities, and decreased the production of malondialdehyde (MDA) and inflammatory factors in alcohol-induced HepG2 cells. …


Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao Nov 2025

Screening And Identification Of Antioxidant Peptides From Sea Cucumber Gonad Proteins And Their Activation Of Superoxide Dismutase, Zhiqin Zhang, Jingxuan Wang, Yongke Deng, Yugui Wang, Peipei Dou, Hongbing Fan, Xiangquan Zeng, Xinguang Fan, Lili Zhang, Haimei Liu, Qin Zhao

Animal and Food Sciences Faculty Publications

The gonad is one of the major byproducts of sea cucumber. Four novel antioxidant peptides (NPWGQ, PGHPF, VPYPR and ATGPQGPAGQRGPAGPTGPTGPAG) were isolated and identified from sea cucumber gonad proteins through enzymatic hydrolysis and antioxidant activity-guided fractionation, bioinformatics approaches and in silico screening. These peptides demonstrated great free radical (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS))-scavenging activity and notable superoxide dismutase (SOD)-activation capacity. Molecular docking and molecular dynamics simulation data suggested that these peptides could form strong binding with SOD through hydrogen bonding, electrostatic interactions, and hydrophobic interactions. Among these peptides, NPWGQ displayed the most potent antioxidant and SOD-activating effects. Through searching …


The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun Nov 2025

The Performance, Energy And Nutrient Utilization, And Bone Mineralization Of Broiler Chickens Fed Corn-Soybean Meal-Based Diets With Reduced Metabolizable Energy, Calcium, And Available Phosphorus Supplemented With Exogenous Enzymes, Megan M. Bauer, Tuoying Ao, Jacqueline P. Jacob, Michael J. Ford, Anthony J. Pescatore, Ronan F. Power, Sunday A. Adedokun

Animal and Food Sciences Faculty Publications

This study evaluated the performance and energy and nutrient utilization of broiler chickens fed corn-soybean meal-based diets supplemented with a naturally fermented enzyme complex containing xylanase and phytase. This was evaluated using 300 one-day-old male Cobb broiler chicks in a randomized complete block design with five dietary treatments replicated 10 times with 6 chicks per replicate. The treatments consisted of a positive control (PC) group containing commercially recommended energy and nutrient levels, a negative control (NC) group with reduced metabolizable energy, calcium, and available phosphorus, and three levels of exogenous enzyme supplementation to the NC diet at 150, 200, 250 …


Law Library Blog (November 2025): Legal Beagle's Blog Archive, Roger Williams University School Of Law Nov 2025

Law Library Blog (November 2025): Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.


Who Classification Of Skin Tumours: Key Updates In The Fifth Edition, Gabrielle Goldman-Lévy, Raymond Barnhill, Boris Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Shahin Sayed Nov 2025

Who Classification Of Skin Tumours: Key Updates In The Fifth Edition, Gabrielle Goldman-Lévy, Raymond Barnhill, Boris Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Shahin Sayed

Pathology, East Africa

The 5th edition of the World Health Organization Classification of Tumours (WCT) serves as a foundation for global diagnostic standards in tumour pathology. Similar to other volumes in this series, the Skin Tumours (Skin5) edition follows a standardized approach. This edition introduces two new chapters: ‘Tumours of the nail unit’ and ‘Metastases to skin’, along with new entities across relevant chapters. This review article provides an overview of the updates in Skin5 based on currently published evidence, with emphasis on newly introduced chapters and newly described entities that involve the skin, in particular, epidermal, melanocytic and appendageal tumours.


Dairy And Food Science News, Nov 2025, Department Of Dairy And Food Science Nov 2025

Dairy And Food Science News, Nov 2025, Department Of Dairy And Food Science

Dairy & Food Science News

Message from the Department Head
Holiday Cheese Boxes
We are Hiring
Dairy and Food Science Department in the Media
Education abroad program to India - Food and Agriculture Processing: India SDSU Fall 2026
Faculty Updates
Surveys and Studies
Recruitment Updates and Opportunities
SDSU Company Student Recruitment
Student Updates
Alumni Spotlight
Events and Calendar


A Tour Of Leukemia Progress In 2025, Viewed Through The Md Anderson Leukemia Research Lens, Hagop M Kantarjian, Gautam Borthakur, Naval Daver, Courtney Dinardo, Guillermo Garcia-Manero, Ghayas Issa, Elias Jabbour, Nitin Jain, Tapan Kadia, Sanam Loghavi, Farhad Ravandi, Guilin Tang, Mary Alma Welch, William Wierda Nov 2025

A Tour Of Leukemia Progress In 2025, Viewed Through The Md Anderson Leukemia Research Lens, Hagop M Kantarjian, Gautam Borthakur, Naval Daver, Courtney Dinardo, Guillermo Garcia-Manero, Ghayas Issa, Elias Jabbour, Nitin Jain, Tapan Kadia, Sanam Loghavi, Farhad Ravandi, Guilin Tang, Mary Alma Welch, William Wierda

Faculty, Staff and Student Publications

Advances in the prognostication, monitoring, and treatment of both the acute and chronic leukemias have led to drastically improved outcomes over the past 2 decades. With the advent of targeted therapies, including antibodies such as blinatumomab and inotuzumab and small molecule inhibitors, such as the BCR::ABL1 tyrosine kinase inhibitors, Bruton tyrosine kinase inhibitors, and venetoclax, the treatment landscape of leukemia has drastically changed, improving survival outcomes while relying less on overall chemotherapy intensity in many leukemia types. This progress has allowed the categorization of more leukemia types as favorable (i.e., chronic lymphocytic leukemia, younger acute lymphoblastic leukemia [patients younger than …


Brain-Wide Patterns Of Crf Receptor 1 Expression In The Transgenic Crfr1-Cre-2a-Tdtom Rat, Douglas S Engelke, Lierni Ugartemendia, Jonathan Tao, Shivakumar Rajamanikam, Fabricio H Do Monte, Nicholas J Justice Nov 2025

Brain-Wide Patterns Of Crf Receptor 1 Expression In The Transgenic Crfr1-Cre-2a-Tdtom Rat, Douglas S Engelke, Lierni Ugartemendia, Jonathan Tao, Shivakumar Rajamanikam, Fabricio H Do Monte, Nicholas J Justice

Faculty, Staff and Student Publications

The ability to manipulate neurons that express corticotropin-releasing factor (CRF) or its receptors has led to many new discoveries about how CRF signaling modulates stress-related behaviors in mice. However, similar advances in rats have been limited by the lack of reporter lines targeting CRF receptors, restricting access to behavioral paradigms that are more suitable for, or specific to, rats. Here, we provide an extensive neuroanatomical characterization of a recently generated CRFR1-Cre rat. We show that Cre and tdTomato are expressed in a pattern that closely aligns with previously reported CRFR1 expression patterns, as determined by in situ hybridization in rats …


Rank-Based Learning: A Novel High-Throughput Algorithm Resilient To Missing Data And Effective For Datasets With Small Sample Size, Lulu Song, Hamid Khoshfekr Rudsari, Johannes F Fahrmann, Jody Vykoukal, Sam Hanash, James P Long, Kim-Anh Do, Ehsan Irajizad Nov 2025

Rank-Based Learning: A Novel High-Throughput Algorithm Resilient To Missing Data And Effective For Datasets With Small Sample Size, Lulu Song, Hamid Khoshfekr Rudsari, Johannes F Fahrmann, Jody Vykoukal, Sam Hanash, James P Long, Kim-Anh Do, Ehsan Irajizad

Faculty, Staff and Student Publications

High-throughput omics data present challenges for binary classification due to platform variability, batch effects, missing values, and high dimensionality. This study presents a novel Rank-Based Learning (RBL) method that leverages relative feature rankings to improve robustness and generalizability. We evaluated RBL against established methods like Logistic Regression (LR) and Random Forest (RF) using simulated data and two real-world plasma proteomics datasets: early-stage small cell lung cancer (SCLC) and duodenopancreatic neuroendocrine tumors (dpNET) in patients with Multiple Endocrine Neoplasia type 1 (MEN1). In simulation experiments, RBL outperformed LR under conditions involving batch effects, missing data, and varying numbers of true differential …


Protein Kinase Giα Oxidation Negatively Regulates Antibody Production By B Cells, Hyun-Ju Cho, Rebecca L Charles, Oleksandra Prysyazhna, Sapna Arjun, Asvi A Francois, Kevin M Mcbride, Philip Eaton Nov 2025

Protein Kinase Giα Oxidation Negatively Regulates Antibody Production By B Cells, Hyun-Ju Cho, Rebecca L Charles, Oleksandra Prysyazhna, Sapna Arjun, Asvi A Francois, Kevin M Mcbride, Philip Eaton

Faculty, Staff and Student Publications

Endogenous oxidants induce a C42-dependent interprotein disulfide between the subunits of protein kinase G (PKG) Iα in cardiovascular tissues to control blood pressure and ventricular relaxation during diastole. PKGIα is expressed in other cell types, including those of the immune system, where the redox state of this kinase is likely to regulate other important physiological processes. The role of PKGIα oxidation in antibody production by B cells, which produce oxidants such as hydrogen peroxide during differentiation, was examined by comparing the immune response of oxidation-resistant C42S PKGIα knock-in (KI) mice to their wild type (WT) littermates.

Immunization with the 4 …


Opposing Roles Of Microglial And Macrophagic C3ar1 Signaling In Stress-Induced Synaptic And Behavioral Changes, Ashutosh Tripathi, Alona Bartosh, Dania Jose, Jocelyn Mata, Usama Hussein, Fernanda Laezza, Zhongming Zhao, Anilkumar Pillai Nov 2025

Opposing Roles Of Microglial And Macrophagic C3ar1 Signaling In Stress-Induced Synaptic And Behavioral Changes, Ashutosh Tripathi, Alona Bartosh, Dania Jose, Jocelyn Mata, Usama Hussein, Fernanda Laezza, Zhongming Zhao, Anilkumar Pillai

Faculty, Staff and Student Publications

The social deficits following chronic stress conditions are linked to synaptic dysfunction in the brain. Complement system plays a critical role in synapse regulation. Although complement has been implicated in chronic stress-induced behavior deficits the cellular substrates and mechanisms underlying complement-mediated behavior changes under chronic stress conditions are not known. In the present study, we investigated the role of complement component 3a receptor (C3ar1) in microglia and monocytes/macrophages (Mo/MΦ) in chronic unpredictable stress (CUS)-induced synapse loss and behavior deficits in mice. We found that deletion of microglial C3ar1 attenuated stress-induced social behavior deficits and changes in neuroinflammatory as well as …


Acute Kidney Injury Is Associated With Elevated Urinary Endotrophin, Amanda J Clark, Brenda Mendoza Flores, Marie Christelle Saade, Kyle Q Vu, Isaac J Pence, Ningyan Zhang, Zhiqiang An, Dawei Bu, Philipp E Scherer, Samir M Parikh Nov 2025

Acute Kidney Injury Is Associated With Elevated Urinary Endotrophin, Amanda J Clark, Brenda Mendoza Flores, Marie Christelle Saade, Kyle Q Vu, Isaac J Pence, Ningyan Zhang, Zhiqiang An, Dawei Bu, Philipp E Scherer, Samir M Parikh

Faculty, Staff and Student Publications

Acute kidney injury (AKI) is prevalent among hospitalized patients. Novel biomarkers are needed to diagnose AKI and target therapies. Endotrophin (ETP) is a molecule released during collagen type VI formation that may promote injury and fibrosis. Although serum ETP elevation has been associated with adverse outcomes in AKI, urinary ETP has not been assessed in AKI, nor has ETP been evaluated in a pediatric population. Urine samples were collected from a tertiary children's hospital. Medical records were reviewed, and patients who met criteria were sorted into three categories:


The Synod: A Journey Through Inculturation To Contextuality, George Worgul Nov 2025

The Synod: A Journey Through Inculturation To Contextuality, George Worgul

Spiritan Horizons

No abstract provided.


Reading The Word And The World: Overstanding Literacy In Aboriginal And Chinese Classrooms, Gui Ying Annie Yang-Heim Nov 2025

Reading The Word And The World: Overstanding Literacy In Aboriginal And Chinese Classrooms, Gui Ying Annie Yang-Heim

Faculty Publications - College of Education

This qualitative comparative case study examines how culturally grounded philosophies of education shape the teaching and learning of reading in two cross-cultural contexts—an Aboriginal Australian classroom and urban Chinese elementary schools. Drawing on interpretive and reflexive methodologies, it investigates how Aboriginal and Confucian epistemologies influence literacy practices and how these practices align with or resist dominant, decontextualized models of reading instruction. Data sources include classroom observations, reading assessments, teacher interviews, and researcher reflections. Conceptually framed by Gadamer’s hermeneutics, Bourdieu’s theory of cultural capital, Habermas’s typology of knowledge, and the Caribbean concept of overstanding, this research finds that Aboriginal literacy is …


Laceration, Children's Mercy Kansas City Nov 2025

Laceration, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


The Functional Connectome Mediates Associations Between Fitness And Cognition Across The Adult Lifespan, Juniad Merchant, Jeremy J. Purcell, Daniel D. Callow, Junyeon Won, Yash Kommula, Samuel Rosenberg, Yi Wei, John L. Woodard, Kristy A. Nielson, Stephen M. Rao, Sally Durgerian, Shuo Chen, J. Carson Smith Nov 2025

The Functional Connectome Mediates Associations Between Fitness And Cognition Across The Adult Lifespan, Juniad Merchant, Jeremy J. Purcell, Daniel D. Callow, Junyeon Won, Yash Kommula, Samuel Rosenberg, Yi Wei, John L. Woodard, Kristy A. Nielson, Stephen M. Rao, Sally Durgerian, Shuo Chen, J. Carson Smith

Psychology Faculty Research and Publications

Cardiorespiratory fitness (CRF) is increasingly recognized as essential for improving neural and cognitive function, especially in older age. Here, we examined a cross-sectional sample of the Human Connectome Project (HCP) Aging dataset (ages 36–100; N = 378) to test the hypothesis that functional connectivity profiles that are related to CRF are also associated with episodic memory and executive function across middle age and older adults. To test these hypotheses, we first used connectome-based predictive modeling (CPM) to identify functional connections (FCs) that were separately predictive of CRF (2 Minute Walk Test), episodic memory (Rey Auditory Verbal Learning Test), and executive …


A Comparison Of Comparisons: Evidence From An International Comparative Study Of 'Smart Cities', Kevin Ward, Teresa Abbruzzese, Tim Bunnell, Paolo Cardullo, I-Chun Catherine Chang, Byron Miller, Ramon Ribera-Fumaz, Haeran Shin, Zachary Spicer, Orlando Woods Nov 2025

A Comparison Of Comparisons: Evidence From An International Comparative Study Of 'Smart Cities', Kevin Ward, Teresa Abbruzzese, Tim Bunnell, Paolo Cardullo, I-Chun Catherine Chang, Byron Miller, Ramon Ribera-Fumaz, Haeran Shin, Zachary Spicer, Orlando Woods

Research Collection College of Integrative Studies

Every year the list lengthens of cities with some sort of ‘smart city’ public policy. In some, it emerges as the latest in a long line of urban digital and information communication policies. In others, the introduction of the notion of the ‘smart city’ marks a departure from past approaches to public policy. Additionally, the more studies emerge of actual smart city policies, then the less definitional agreement there seems to be. Nevertheless, that we have witnessed in the last two decades the ‘repeated instance’ of smart cities emerging in cities around the world seems incontrovertible. Like so much urban …


Nationalism And Anglo-American Neo-Colonialism In Southeast Asia, 1945-1965, Wen-Qing (Wei Wenqing) Ngoei Nov 2025

Nationalism And Anglo-American Neo-Colonialism In Southeast Asia, 1945-1965, Wen-Qing (Wei Wenqing) Ngoei

Research Collection College of Integrative Studies

It is tempting to treat the United States’ ill-fated military intervention in Vietnam in the 1960s as the desperate final gasp of a moribund Western imperial system. Certainly, scholars have described Washington’s military debacle in Vietnam as the end of America’s “short-lived empire” in Southeast Asia, emblematic of the broader, decisive triumph of Southeast Asian nationalism over western colonialism. This reading of Southeast Asian countries attaining formal independence after 1945, with tacit assumptions that colonialism and nationalism exist in binary opposition, tends to ossify when the region’s history is viewed through the lens of U.S. defeat in Vietnam.

In contrast, …


Misfolded Amyloid-Beta Conformational Variants (Strains) As Drivers Of Alzheimer's Disease Neuropathology, Salvatore Saieva, Rodrigo Morales Nov 2025

Misfolded Amyloid-Beta Conformational Variants (Strains) As Drivers Of Alzheimer's Disease Neuropathology, Salvatore Saieva, Rodrigo Morales

Faculty, Staff and Student Publications

No abstract provided.


Sars-Cov-2 Mrna Vaccines Sensitize Tumours To Immune Checkpoint Blockade, Adam J Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna Devries, Paul Castillo, Rishabh Lohray, Michael K Rooney, Benjamin R Schrank, Yifan Wang, Yifan Ma, Enoch Chang, Ramez Kouzy, Kyle Dyson, Jordan Jafarnia, Nina Nariman, Gregory Gladish, Jacob New, Ada Argueta, Diana Amaya, Nagheme Thomas, Andria Doty, Joe Chen, Nikhil Copling, Gabriel Alatrash, Julie Simon, Alicia Bea Davies, William Dennis, Richard Liang, Jeff Lewis, Xiong Wei, Waree Rinsurongkawong, Ara A Vaporciyan, Andrew Johns, D3code Team, Jack Lee, Ji-Hyun Lee, Ryan Sun, Padmanee Sharma, Hai Tran, Jianjun Zhang, Don L Gibbons, Jennifer Wargo, Betty Y S Kim, John V Heymach, Hector R Mendez-Gomez, Wen Jiang, Elias J Sayour, Steven H Lin Nov 2025

Sars-Cov-2 Mrna Vaccines Sensitize Tumours To Immune Checkpoint Blockade, Adam J Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna Devries, Paul Castillo, Rishabh Lohray, Michael K Rooney, Benjamin R Schrank, Yifan Wang, Yifan Ma, Enoch Chang, Ramez Kouzy, Kyle Dyson, Jordan Jafarnia, Nina Nariman, Gregory Gladish, Jacob New, Ada Argueta, Diana Amaya, Nagheme Thomas, Andria Doty, Joe Chen, Nikhil Copling, Gabriel Alatrash, Julie Simon, Alicia Bea Davies, William Dennis, Richard Liang, Jeff Lewis, Xiong Wei, Waree Rinsurongkawong, Ara A Vaporciyan, Andrew Johns, D3code Team, Jack Lee, Ji-Hyun Lee, Ryan Sun, Padmanee Sharma, Hai Tran, Jianjun Zhang, Don L Gibbons, Jennifer Wargo, Betty Y S Kim, John V Heymach, Hector R Mendez-Gomez, Wen Jiang, Elias J Sayour, Steven H Lin

Faculty, Staff and Student Publications

Immune checkpoint inhibitors (ICIs) extend survival in many patients with cancer but are ineffective in patients without pre-existing immunity1–9. Although personalized mRNA cancer vaccines sensitize tumours to ICIs by directing immune attacks against preselected antigens, personalized vaccines are limited by complex and time-intensive manufacturing processes10–14. Here we show that mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to ICIs. In preclinical models, SARS-CoV-2 mRNA vaccines led to a substantial increase in type I interferon, enabling innate immune cells to prime CD8+ T cells that target tumour-associated antigens. Concomitant ICI treatment is required for …


The Epidemiology Of Us Upper Extremity Amputations: An Analysis Of The Global Burden Of Disease Database (1990-2019)., Ambrose Loc T Ngo, Cameron J Sabet, Gabrielle Dykhouse, Ayah Ibrahim, Taylor J Manes, Arsalaan Sayyed, Shaheryar Asad, Benjamin C Taylor Nov 2025

The Epidemiology Of Us Upper Extremity Amputations: An Analysis Of The Global Burden Of Disease Database (1990-2019)., Ambrose Loc T Ngo, Cameron J Sabet, Gabrielle Dykhouse, Ayah Ibrahim, Taylor J Manes, Arsalaan Sayyed, Shaheryar Asad, Benjamin C Taylor

Surgery Articles

Background Upper extremity amputations (UEAs) are medically, psychologically, and functionally devastating. This study aimed to evaluate region- and sex-specific differences in unilateral and bilateral upper extremity amputations in the United States (US) from 1990 to 2019. Methods The Global Burden of Disease (GBD) database was used to analyze years lived with disability (YLDs), prevalence, and incidence rates per 100,000 people for upper extremity amputations in the US from 1990 to 2019. Data were stratified into four US Census Bureau-defined regions: Northeast, Midwest, South, and West. Differences between regions and sexes were assessed, with statistical significance defined as p< 0.05. Results Between 1990 and 2019, unilateral upper extremity amputations in the US showed a 34.51% decrease in YLDs, 34.34% in prevalence, and 37.38% in incidence. Bilateral amputations decreased by 51.32%, 48.94%, and 56.80%, respectively. Men consistently had higher YLDs, prevalence, and incidence rates for unilateral amputations (p< 0.001). Regionally, the Northeast had the highest mean YLDs, prevalence, and incidence, while the South had the lowest. Men also experienced significantly higher rates of both unilateral and bilateral amputations across all regions compared to women (p< 0.05). Conclusions From 1990 to 2019, the US experienced declines in YLDs, prevalence, and incidence of upper extremity amputations. Men had higher rates than women across all regions. The Northeast exhibited the highest rates, while the South had the lowest. These findings underscore notable gender and regional disparities in upper extremity amputation trends.


Critical Young Consumers: What Types Of Porn Do Teens Watch, And Why?, Giselle Woodley, Marc Zen, Harrison W. See, Lelia Green Nov 2025

Critical Young Consumers: What Types Of Porn Do Teens Watch, And Why?, Giselle Woodley, Marc Zen, Harrison W. See, Lelia Green

Research outputs 2022 to 2026

Pornography use by teens is of growing concern to parents and communities. There is, however, often little differentiation made between the types of contents being consumed or exploration of the types of pornography teens are watching and why. This paper interrogates data collected from 49 qualitative interviews, including 19 follow-up interviews and 4× focus groups with teens. This paper explores teens’ perspectives on the types of pornography accessed by themselves and their peers, and popular categories of pornography more widely. Teens appear to view various types and genres of pornography, as do adults. Some teens prefer ‘ethical’ sources of porn, …


Gilbert’S Potoroo And The Fun-Guys: Co-Existing Mycophagous Mammals As Indicators Of Potentially Available Fungal Food Resources, Rebecca J. Quah, James Anthony Friend, Aaron J. Brace, Saul J. Cowen, Robert A. Davis, Harriet R. Mills, Anna J.M. Hopkins Nov 2025

Gilbert’S Potoroo And The Fun-Guys: Co-Existing Mycophagous Mammals As Indicators Of Potentially Available Fungal Food Resources, Rebecca J. Quah, James Anthony Friend, Aaron J. Brace, Saul J. Cowen, Robert A. Davis, Harriet R. Mills, Anna J.M. Hopkins

Research outputs 2022 to 2026

Understanding resource use and availability is critical for the success of wildlife translocations, especially for species with complex diets. Mycophagous (fungus-feeding) diets are particularly challenging to study due to the difficulty in identifying fungal species, many of which remain undescribed. Environmental DNA (eDNA) metabarcoding techniques applied to scat samples, offer a promising solution to overcome the limitations of traditional dietary analysis involving microscopic identification of undigested material in scats. This allows for the detailed characterization of fungal composition in the diets of mycophagous species. Here we present results of a dietary study focused on Gilbert’s potoroo (Potorous gilbertii) that also …


Skin Soft Tissue Infection: Antibiotics For Abscesses, Children's Mercy Kansas City Nov 2025

Skin Soft Tissue Infection: Antibiotics For Abscesses, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.


Interaction2code: Benchmarking Mllm-Based Interactive Webpage Code Generation From Interactive Prototyping, Jingyu Xiao, Yuxuan Wan, Yintong Huo, Zixin Wang, Xinyi Xu, Wenxuan Wang, Zhiyao Xu, Yuhang Wang, Michael R. Lyu Nov 2025

Interaction2code: Benchmarking Mllm-Based Interactive Webpage Code Generation From Interactive Prototyping, Jingyu Xiao, Yuxuan Wan, Yintong Huo, Zixin Wang, Xinyi Xu, Wenxuan Wang, Zhiyao Xu, Yuhang Wang, Michael R. Lyu

Research Collection School Of Computing and Information Systems

Multimodal Large Language Models (MLLMs) have demonstrated remarkable performance on the design-to-code task, i.e., generating UI code from UI mock-ups. However, existing benchmarks only contain static web pages for evaluation and ignore the dynamic interaction, limiting the practicality, usability and user engagement of the generated webpages. To bridge these gaps, we present the first systematic investigation of MLLMs in generating interactive webpages. Specifically, we formulate the Interaction-to-Code task and establish the Interaction2Code benchmark, encompassing 127 unique webpages and 374 distinct interactions across 15 webpage types and 31 interaction categories. Through comprehensive experiments utilizing state-of-theart (SOTA) MLLMs, evaluated via both automatic …


باستخدام مجموعة بيانات متعددة من الطائرات بدون طيار Yolo البحث والإنقاذ البحري القائم على في ظروف الطقس الصعبة, Aysha Ali Alshebli Nov 2025

باستخدام مجموعة بيانات متعددة من الطائرات بدون طيار Yolo البحث والإنقاذ البحري القائم على في ظروف الطقس الصعبة, Aysha Ali Alshebli

Theses

Object detection models, powered by deep learning and computer vision, are revolutionizing marine search and rescue (SAR). By analyzing aerial imagery and live drone footage, these systems automatically identify critical targets like survivors, life rafts, and debris across vast and treacherous ocean areas. This capability enhances operational efficiency by reducing human workload and accelerating response times, even in challenging conditions such as poor light, high seas, or cluttered backgrounds. The result is continuous monitoring, faster decision-making, and a significantly improved probability of successful rescue.

Departing from prior methodologies, YOLO introduced a paradigm shift through its single-shot architecture, which concurrently predicts …