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2025

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Investigating The Role And Expression Of Aquaporin 10 Paralogs In Spiny Dogfish (Squalus Acanthias), Esosa Omoregie Jan 2025

Investigating The Role And Expression Of Aquaporin 10 Paralogs In Spiny Dogfish (Squalus Acanthias), Esosa Omoregie

College of Graduate Studies: Theses & Dissertations

Aquaporins (AQPs) are integral membrane proteins that facilitate the selective transport of water and small solutes across cell membranes, playing essential roles in maintaining osmotic balance in vertebrates. Among them, aquaglyceroporins such as AQP10 are capable of transporting water, glycerol, and urea, contributing to osmoregulatory and metabolic processes. This study investigated the expression, localization, and potential physiological roles of two AQP10 paralogs, AQP10C1 and AQP10C2, in the spiny dogfish (Squalus acanthias), a marine elasmobranch that maintains osmotic equilibrium through urea retention and ion regulation. Using RT-PCR, quantitative PCR, Western blotting and immunohistochemistry the study identified tissue-specific expression patterns of …


Toward Objectivity In International Criminal Law: Modeling Genocide, Kevin Chamow Jan 2025

Toward Objectivity In International Criminal Law: Modeling Genocide, Kevin Chamow

Student Works

No abstract provided.


A Case For Further Environmental Protections Of Endangered Animals’ Habitats And A Limitation Of State Agency Power, Jacob T. Norris Jan 2025

A Case For Further Environmental Protections Of Endangered Animals’ Habitats And A Limitation Of State Agency Power, Jacob T. Norris

Student Works

No abstract provided.


Clinical Predictors Of Fluid-Responsive Acute Kidney Injury, Cindy Khanh Nguyen Jan 2025

Clinical Predictors Of Fluid-Responsive Acute Kidney Injury, Cindy Khanh Nguyen

Yale Medicine Thesis Digital Library

CLINICAL PREDICTORS OF FLUID-RESPONSIVE ACUTE KIDNEY INJURY

Cindy Khanh Nguyen, Abinet M. Aklilu, Yu Yamamoto, Bashar A. Kadhim, Claudia Coronel-Moreno, Francis P. Wilson. Section of Nephrology, Department of Internal Medicine, Yale University, School of Medicine, New Haven, CT.

Specific Aims: We aimed to explore and identify common clinical variables that may be helpful in selecting patients who will benefit from volume challenge when the fluid-responsiveness of AKI is unclear.

Methods: Our study is a retrospective secondary analysis of a clinical trial that prospectively enrolled adult patients at Yale-New Haven Hospital with AKI defined by the 2012 Kidney Disease: Improving Global …


Review Of Two Books By Andrew Furman, J "Sudsy" M. Tschiderer Jan 2025

Review Of Two Books By Andrew Furman, J "Sudsy" M. Tschiderer

Florida Geographer

Grab a sun hat and your binoculars. Retreat from air-conditioning and step outside. Listen to the heady mixture of calm and chaos in the great outdoors of your yard, urban or rural. Bend down and look closely at the thriving world beneath your feet. A dose of Andrew Furman’s meticulously crafted essays on life in Florida compels one to forego summer’s inertia and soak up the extraordinary landscape most of us take for granted every day. Both books offer a thought-provoking, “highly selective” synthesis of Florida life and geography as viewed through the prism of an intuitive writer. Reading the …


A Spoonful Of Sugar Won’T Help This Medicine Go Down: The Inflation Reduction Act’S Failure To Address Pharmaceutical Evergreening, Megan E.A. Davis Jan 2025

A Spoonful Of Sugar Won’T Help This Medicine Go Down: The Inflation Reduction Act’S Failure To Address Pharmaceutical Evergreening, Megan E.A. Davis

Oklahoma Law Review

No abstract provided.


Only Mostly Dead: How The Irreparable Injury Rule Can Protect The Jury Trial Right For Claims In Restitution, Layne Keele Jan 2025

Only Mostly Dead: How The Irreparable Injury Rule Can Protect The Jury Trial Right For Claims In Restitution, Layne Keele

Oklahoma Law Review

No abstract provided.


Putting The “Social” Into Social Determinants Of Health: Why Policymaking For Improving Health Must Tackle Social Isolation And Loneliness, Laura C. Hoffman Jan 2025

Putting The “Social” Into Social Determinants Of Health: Why Policymaking For Improving Health Must Tackle Social Isolation And Loneliness, Laura C. Hoffman

Oklahoma Law Review

No abstract provided.


Should Clients Have A Right To Know What Their Lawyer Believes?, Melissa D. Mortazavi Jan 2025

Should Clients Have A Right To Know What Their Lawyer Believes?, Melissa D. Mortazavi

Oklahoma Law Review

No abstract provided.


Predictors Of Facultative Siblicide In Black-Legged Kittiwake (Rissa Tridactyla) Chicks, Maria Pisciotta Jan 2025

Predictors Of Facultative Siblicide In Black-Legged Kittiwake (Rissa Tridactyla) Chicks, Maria Pisciotta

Honors Theses

In Black-legged kittiwakes (Rissa tridactyla), a seabird species, competition between siblings can arise when more than one chick is present in a nest. The first-hatched chick, known as the “A” chick, frequently establishes dominance over the second-hatched chick, known as the “B” chick. Many different factors can drive the presence and intensity of this competition, including the size discrepancies between chicks, and their physiological state. A likely factor is resource limitation, seen in many instances of sibling competition to be a prominent component because limited food must be allocated between both chicks by parents. In some cases, competition can escalate …


The Aussie Oddballs: Identifying The Existence Of Censer And Trample Burr Dispersal In Australian Bush Tomatoes, Abigail Motter Jan 2025

The Aussie Oddballs: Identifying The Existence Of Censer And Trample Burr Dispersal In Australian Bush Tomatoes, Abigail Motter

Honors Theses

Australian bush tomatoes in northern Western Australia likely have seed dispersal mechanisms that depend on processes outside of frugivory, which is unusual for this genus. Solanum tudununggae seeds are wind dispersed by the censer mechanism, meaning that seeds fall from holes in the top of the fruit when the branches move. In another species, piles of abscised and burr-like fruits have been found strewn around the bases of S. ossicruentum, possibly due to the extinction of animals that may have been a means of dispersal via epizoochory. In this study, we attempt to provide support for the theorized dispersal …


The Alien Language: Game The Developmental Trajectory Of Auditory And Visual Statistical Learning, Gwen Radecki Jan 2025

The Alien Language: Game The Developmental Trajectory Of Auditory And Visual Statistical Learning, Gwen Radecki

Honors Theses

Statistical learning (SL) extends across multiple stimulus domains and modalities, including vision, audition, and touch. However, it remains to be seen whether SL is supported by a modality-general or modality-specific mechanism(s). Prior work examined this by varying the rate of presentation across modalities, finding evidence of modality-specific constraints on learning (Emberson, Conway & Christiansen, 2011). In a prior experiment, I extended this work by testing the effect of presentation rate in standardized audio and visual SL tasks. The results of this project provided evidence against modality constraints to SL, suggesting instead that the mechanism is modality-general in nature. However, SL’s …


Backyard Chimeric Microbiomes: K-12 Participatory Science, Abigail Saucier Jan 2025

Backyard Chimeric Microbiomes: K-12 Participatory Science, Abigail Saucier

Honors Theses and Capstones

The US education system has seen a recent push for more secondary school curriculum to include STEM (Science, Technology, Engineering, and Mathematics) materials and activities. Middle and high school is a pivotal time when academic and personal experiences affect the development of student attitudes towards STEM (Christensen et al., 2015; Moreno et al., 2016). Teachers often utilize hands-on activities to promote student engagement with science curriculum (Brooks & Poles, 2021; Christensen et al., 2015). Hands-on activities improve student learning, but impacts vary by type of activity. When students work towards a known outcome they can feel disconnected from the work …


The North American Gap Ungulates Must Migrate Physically And Legally: Elk As A Case Study, Alex Wendlandt Jan 2025

The North American Gap Ungulates Must Migrate Physically And Legally: Elk As A Case Study, Alex Wendlandt

Wyoming Law Review

Humans have tracked elk hoof prints in North America since ancient times, recognizing the significance of these migratory ungulates in culture, mythology, dietary value, and utility. As migratory ungulates, elk respond to changes in their environment by migrating to and from their summer and winter ranges. Today, elk migrations continue across the jurisdictional boundary of the northern United States and southern Canada, spreading ecological and economic benefits with each track they make. Unfortunately, ungulate migration is an “endangered phenomenon” due to loss of connectivity and loss of habitat. While the United States and Canada have acknowledged the importance of, and …


Arizona V. Navajo Nation's Impact On The United States-Indian Trust Framework, Kegan S. Peters Jan 2025

Arizona V. Navajo Nation's Impact On The United States-Indian Trust Framework, Kegan S. Peters

Water Law Review

No abstract provided.


Student Handbook 2025-2026, Collin College Jan 2025

Student Handbook 2025-2026, Collin College

Handbooks

The Collin College Student Handbook contains information on student services, resources, and opportunities designed to make your experience at Collin College more meaningful and productive. The Collin College Student Handbook also includes the Student Code of Conduct which explains Collin College's expectations for students' behavior.


Front Matter: Cover Page, Letter From The Editors, And Editorial Board, Endeavors Journal Jan 2025

Front Matter: Cover Page, Letter From The Editors, And Editorial Board, Endeavors Journal

Endeavors: Mississippi State Undergraduate Research Journal

No abstract provided.


Bovine Serum Albumin (Bsa) Impacts Morphology Of Fowler’S Toad (Anaxyrus Fowleri) Sperm During Short-Term Cold Storage, Jane A. Dill, Michelle K. Roy, Renato E. Naranjo, Andrew J. Kouba, Carrie K. Vance Jan 2025

Bovine Serum Albumin (Bsa) Impacts Morphology Of Fowler’S Toad (Anaxyrus Fowleri) Sperm During Short-Term Cold Storage, Jane A. Dill, Michelle K. Roy, Renato E. Naranjo, Andrew J. Kouba, Carrie K. Vance

Endeavors: Mississippi State Undergraduate Research Journal

Short-term cold storage of amphibian sperm is a valuable technique for overcoming challenges associated with asynchronous gamete release during breeding events or for transferring sperm between institutions for genetic management. Unfortunately, sperm longevity declines over time even when kept cool. Maintaining sperm form and function is critical to achieving the highest possible fertilization rates. Thus, cold storage of amphibian sperm would benefit from the addition of compounds that could extend their quality, improve fertilization and result in more offspring. One such compound is bovine serum albumin (BSA), which provides membrane stabilization, prevents lipid peroxidation of cells, protects against free radical …


The Mirror Of Scripture: Historical Memory, Translation, And The Bible In Early Modernity, 1450-1660, Colin Glen Hoch Jan 2025

The Mirror Of Scripture: Historical Memory, Translation, And The Bible In Early Modernity, 1450-1660, Colin Glen Hoch

Yale Graduate School of Arts and Sciences Dissertations

Contributing to the latest thematic trends in early modern studies, this dissertation project maintains that contested historical memory, or the competing ways that European Christians envisioned themselves as part of an ancient and authoritative biblical tradition, constituted the creative engine at the heart of shaping the early modern Bible (c.1450- 1660). In an era when successful claims to custom and antiquity conferred the highest legitimacy, historical memory was a critical source of identity and authority, even if, as recent theorists of early modern memory assert, memory itself meant something different in the period. The Bible in myriad forms served as …


Sex-Specific Roles Of The Adipocyte Mineralocorticoid Receptor In Obesity And Early Life Stress, Meghan B. Turner Jan 2025

Sex-Specific Roles Of The Adipocyte Mineralocorticoid Receptor In Obesity And Early Life Stress, Meghan B. Turner

Theses and Dissertations--Pharmacology and Nutritional Sciences

Obesity is a burgeoning health epidemic caused by chronic overnutrition and exacerbated by genetic, environmental and developmental factors. The adipocyte mineralocorticoid receptor (MR), a transcriptionally active nuclear receptor, is speculated to contribute to metabolic dysfunction in the obese state. MR expression is increased in obese adipose tissue, and MR modulates the expression of fat-derived hormones such as leptin and adiponectin. In women, obesity can be exacerbated by early life stress, such as adverse childhood experiences (ACEs). Studies show that women display a positive association between cumulative ACE exposures and increased body mass index. Previously, we demonstrated that maternal separation and …


Online Inclusivity: Mission And Best Practice, Colin P. Marks, Zoe Niesel Jan 2025

Online Inclusivity: Mission And Best Practice, Colin P. Marks, Zoe Niesel

Faculty Works

This essay examines the role of inclusivity as a foundational principle in online legal education, arguing that it is essential to fulfilling institutional missions, aligning with established pedagogical best practices, and enhancing the overall learning experience. Drawing on the development of a fully online J.D. program, the piece outlines how inclusivity can be embedded at both the institutional and classroom levels. It highlights strategies for fostering a sense of community among geographically dispersed students, including integrating online learners into broader academic and co-curricular activities, designing courses that balance synchronous and asynchronous instruction, and implementing consistent instructional standards. The essay further …


Defining The Field Of Wellness Law, Barbara Zabawa Jan 2025

Defining The Field Of Wellness Law, Barbara Zabawa

Faculty Works

Some lawyers practice “wellness law” without knowing what it is and how it differs from more recognized fields of practice such as health law, public health law, and medical malpractice. This article defines the field of wellness law using in a prescriptive manner the organizational framework that identifies the common and distinctive patterns in wellness and the law that surrounds it. This examination entails reviewing statutes and cases that differentiate between conventional health care and products or services outside of it to identify the core problems that are common and unique to wellness law. Those core problems are twofold. First, …


No Detected Signal Of The 2022 Epizootic From Multiannual Diadema Antillarum Settlement Data In The Florida Keys, Jason Albrecht Jan 2025

No Detected Signal Of The 2022 Epizootic From Multiannual Diadema Antillarum Settlement Data In The Florida Keys, Jason Albrecht

Theses, Dissertations and Culminating Projects

The sea urchin Diadema antillarum is a key coral reef grazer that remains functionally extinct on many Caribbean reefs following a mass mortality event in 1983–84. In 2022, another widespread mortality event, likely caused by a scuticociliate parasite, again decimated D. antillarum at reefs across the Caribbean. Understanding the population-level impacts of this recent epizootic will be important for coral reef conservation efforts. This study examines multi-year larval settlement data from the Florida Keys to determine if the 2022 mortality event reduced larval settlement. Larval settlement was assessed monthly at three long-term monitoring sites (Delta Shoal, Tennessee Reef, and Pickles …


Domestic Direct Agricultural Exports And Export Spillovers From Foreign Export Intermediary Firms: Evidence From Tanzania, John S. M. Shilinde, Ari Kokko, Vincent Leyaro Jan 2025

Domestic Direct Agricultural Exports And Export Spillovers From Foreign Export Intermediary Firms: Evidence From Tanzania, John S. M. Shilinde, Ari Kokko, Vincent Leyaro

Journal of African Trade

This study examines the impact of foreign intermediaries on Tanzanian domestic direct exporting firms’ ability to expand their export volume. Using panel gravity PPML model to firm-level agricultural exports dataset 2010-2020, we find that foreign intermediaries significantly promote domestic firms’ intensive margins of exports. The geographic clustering of foreign intermediaries exporting comparable goods to similar destination generates significant positive spillover effects on domestic firms based in the same region. This suggests, the companies with product-destination-market pairings have the greatest export spillover effects that are likely related to knowledge transfers generated foreign firms from their country of origin.


The Potential Impact Of The African Continental Free Trade Area On Ethiopia's Total Exports And Real Gdp Growth, Simachew Zelalem Mengistu Jan 2025

The Potential Impact Of The African Continental Free Trade Area On Ethiopia's Total Exports And Real Gdp Growth, Simachew Zelalem Mengistu

Journal of African Trade

This study examines the potential impact of the African Continental Free Trade Area (AfCFTA) on Ethiopia's export growth and real GDP using the General Equilibrium Poisson Pseudo Maximum Likelihood (GEPPML) estimation model. Despite Africa's longstanding efforts toward economic integration, intra-African trade remains low, with Ethiopia's export structure heavily reliant on primary agricultural commodities and limited diversification into high-value or technology-intensive sectors. The paper employs a three-stage GEPPML approach to simulate the effects of AfCFTA, accounting for trade elasticities, multilateral resistance terms, and endogenous income adjustments.

The findings indicate that AfCFTA could enhance Ethiopia's export growth by 1.137% and real GDP …


Approximating The First-Order Effects Of Afcfta Tariff Reductions On Co2 Emissions, Jaime De Melo, Jean-Marc Solleder Jan 2025

Approximating The First-Order Effects Of Afcfta Tariff Reductions On Co2 Emissions, Jaime De Melo, Jean-Marc Solleder

Journal of African Trade

This paper explores how AfCFTA tariff reductions affect CO₂ emissions. Using sector-level data, we find that more protected sectors are also more carbon intensive, so liberalization risks favoring “dirtier” activities. However, for EAC and ECOWAS, tariff cuts on liberalized goods reduce average carbon intensity. A full liberalization scenario suggests intra-African trade could rise by 32% while emissions grow by 24%, implying a modest decline in emission intensity. AfCFTA thus expands trade but requires complementary green policies.


When The Executive Has Unclean Hands, William Baude, Samuel L. Bray Jan 2025

When The Executive Has Unclean Hands, William Baude, Samuel L. Bray

Public Law and Legal Theory Working Papers

Those who come into equity must come with clean hands. But what happens when it is the executive who seeks equitable relief? This Essay argues that the unclean-hands doctrine applies to the executive, though in a modified form that reflects the relation- ships between officials in the executive branch, between the executive and legislative branch, and between the government and the people. It then applies the doctrine to current controversies such as government requests for stays from the Supreme Court, and a pending lawsuit against the District of Maryland.


Unlocking Human-Robot Dynamics In Restaurants: Exploring The Mechanisms Underlying The Impacts Of Service Robots’ Social Cues On Restaurant Customer Behaviors, Yusi Cheng Jan 2025

Unlocking Human-Robot Dynamics In Restaurants: Exploring The Mechanisms Underlying The Impacts Of Service Robots’ Social Cues On Restaurant Customer Behaviors, Yusi Cheng

Graduate Thesis and Dissertation post-2024

The rise of service robots (SRs) is reshaping service delivery, particularly in the dining sector where guiding and delivering robots are increasingly prevalent. However, understanding how customers interact with SRs and respond to their social cues in the dining environment remains unclear and fragmented. This dissertation aims to bridge this gap by comprehensively understanding the social cues of SRs and their influences on customer behaviors. Specifically, the objectives are to (1) understand prominent social cues and customer responses; (2) identify key SR-related social cues; (3) explore customer-SR interaction outcomes; (4) explain why certain social cues elicit particular customer responses; (5) …


Fgf19 Facilitates Metastatic Phenotypes In Colorectal Cancer, Joseph W. Nolff Jan 2025

Fgf19 Facilitates Metastatic Phenotypes In Colorectal Cancer, Joseph W. Nolff

Graduate Thesis and Dissertation post-2024

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. With 154,000 new cases estimated in 2025, there is an increased need for early screening to detect CRC prior to metastasis. Our laboratory has focused on enteroendocrine hormone Fibroblast Growth Factor-19 (FGF19) as it is overexpressed in a subset of CRC tumors. FGF19 is an intestinal-derived hormone involved with lipid homeostasis when bound to its receptor, Fibroblast Growth Factor Receptor-4 (FGFR4). Our objective focuses on FGF19 contribution towards an epithelial-to-mesenchymal transition (EMT) and overall metastatic properties including rapid proliferation and/or increased cell motility. Immunofluorescence was …


Fructose Induces Metabolic Changes Distinctly Different From Glucose In A N2a Cell Line., Catherine A. Ghigleri Jan 2025

Fructose Induces Metabolic Changes Distinctly Different From Glucose In A N2a Cell Line., Catherine A. Ghigleri

All Master's Theses

Over the last 50 years, there has been a rise in diagnoses of Alzheimer’s Disease and other dementias associated with metabolic stress. This parallels an increase in fructose consumption and has led to research on the effects of fructose on the hippocampus, a brain structure responsible for learning and long-term memory formation. The hippocampus is also a region of the brain that metabolizes fructose. Experiments using animals fed diets containing fructose have shown a correlation between fructose consumption, learning impairment, and structural changes to the hippocampus in animals’ brains. However, the effects of fructose on hippocampal neurons have not been …