Digital Commons Network^™

How Anime Changed My Life, Carissa Gonzalez

Celebrating Writers and Writing in our Communities

No abstract provided.

Volume 12 Issue 4 (Jan 1912)

The Soul Winner

No abstract provided.

Exploring The Challenges And Interventions For Type 1 Diabetes In Young Children, Patra Chisom Ezeamii, Nenrot Gopep, Ho-Jui Tung

Eagles Talking About the Public’s Health

No abstract provided.

The Fortunate Demise Of Sec Staff Legal Bulletin No. 14l, Raffaele Felicetti

Fordham Journal of Corporate & Financial Law

In 2021, the SEC published its now rescinded Staff Legal Bulletin No. 14L (“the 2021 Bulletin”), revising its interpretations of the “ordinary business” and “economic relevance” exclusions under Rule 14a-8. This Article contends that the post-Bulletin landscape has proven undesirable. It empirically shows that environmental and social (“E & S”) shareholder proposals—including anti-E&S proposals—surged in response. Between 2022 and 2024 alone, E & S proposals accounted for 40% of all such filings in Russell 3000 companies over the entire 2014-2024 period, generating an estimated $23.3 million in additional processing costs for companies during that three-year window. Despite their volume, these …

Use Of Coculture And Carbon Source Manipulation To Stimulate Antibiotic Production In Soil-Dwelling Microbes, April R. Dembinski

Senior Honors Theses and Projects

This study aimed to discover new antibiotics produced by soil microbes. Previous studies have shown that manipulation of microbial growth conditions through variable carbon sources and growth in coculture could induce the production of novel antibiotics by soil microbes. This study expanded on these observations by testing the levels of antibiotic production when a producing strain was grown in twenty different carbon sources and cocultured with more than one hundred different coculture partners. Organic extracts from liquid cultures were tested against a panel of four safe relatives to ESKAPE pathogens and one yeast to detect antimicrobial activity. Certain combinations of …

Beyond Vulnerability: Climate Change And The Moral Authority Of Youth, Amber Acquaye

Yale Medicine Thesis Digital Library

Young people worldwide demand a voice in climate governance, yet their perspectives remain largely excluded from the moral frameworks that shape climate policy. This exclusion not only marginalizes children’s lived experiences and ethical reasoning but also perpetuates paternalistic norms and dangerous marginalization. To counter this, this thesis study shows that youth are not just passive stakeholders but moral agents whose perspectives yield a more just and comprehensive understanding of climate responsibility. Recognizing their ethical insights is crucial for medicine, especially pediatrics and child psychiatry, given how climate change amplifies health risks like respiratory illnesses, heat-related conditions, and eco-anxiety. Understanding how …

Quantitative Assessment Of Facial Ptosis In Face Transplantation, Sam Boroumand

Yale Medicine Thesis Digital Library

As a transformative surgical procedure, face transplantation restores form and function to patients with severe facial disfigurements, yet the long-term aging dynamics of transplanted tissues remain poorly characterized. This study aimed to investigate the progression of facial ptosis in transplanted facial allografts over time, addressing a critical gap in the understanding of long-term outcomes following face transplantation. Specific aims include quantifying ptosis progression using cephalometric measurements, identifying regional variations in the degree of ptosis across the face, and comparing changes between face transplant recipients and a non-face transplanted control cohort to contextualize findings.

To assess these aims, standardized frontal headshots …

“A Double-Edged Sword”: Influence Of The 21st Century Cures Act On The Childhood Cancer Care Experience, Mona Clappier

Yale Medicine Thesis Digital Library

The 21st Century Cures Act yielded policy change that allows patients toimmediately access components of their electronic health record (EHR) via an online portal. For children, adolescents, and young adults (AYAs) with cancer and their families, this federal mandate has profound implications. We sought to explore how immediate EHR portal access influences the childhood cancer care experience. We conducted semi-structured interviews with key informants, including parents of children with cancer, AYAs with cancer, and pediatric oncology healthcare professionals, at three National Cancer Institute-designated comprehensive cancer centers. Interviews were recorded, transcribed, and thematically analyzed. Across 84 participants, 71% self-identified as women …

Effectiveness Of Interventions For Depressive Symptoms After Spinal Cord Injury: A Systematic Review, Robert Cotter

Yale Medicine Thesis Digital Library

Our aims were to summarize and evaluate evidence regarding the efficacy ofinterventions for depressive symptoms in adults living with spinal cord injury (SCI) and comorbid major depressive disorder or significant depressive symptoms to inform the development of clinical practice guidelines. Articles published since 2013 and available in Medline, The Cochrane Library, Embase, Scopus, CINAHL, or PsycINFO were evaluated. Databases were searched in June 2022 and updated November 2023. Inclusion criteria: age 18 years or older, traumatic SCI, and clinically significant depression (Population), mental health interventions including behavioral, pharmacological, and complementary and alternative medicine (Intervention), inclusion of a control group (Comparator), …

Trends In Missing Race And Ethnicity Data In A National Surgical Database, Kevin Gao Hu

Yale Medicine Thesis Digital Library

Accurate data collection on race and ethnicity is critical to detecting and characterizing disparities in surgical care. This study explores the prevalence and impact of missing race and ethnicity data in the National Surgical Quality Improvement Project Pediatric (NSQIP Pediatric) database. NSQIP Pediatric from 2016-2020 was assessed for patients who were missing data for race (RM), ethnicity (EM), or both (BM). Changes in proportion of RM, EM, and BM patients were assessed with Cochran-Armitage tests. Surgical outcomes were modeled using linear mixed-effects models, treating CPT codes as random effects. Models were bootstrapped with 1000 iterations for each outcome. Of 596,571 …

Exploring The Journey To Heart Failure Diagnosis In Uganda, Teimur Kayani

Yale Medicine Thesis Digital Library

This study sought to explore the healthcare journeys of patients recently diagnosed with heart failure (HF) in Uganda. Using a semi-structured guide developed in collaboration with Ugandan colleagues, we conducted in-depth interviews with 19 patients diagnosed with HF within the past three months across four regional referral hospitals in Uganda. Interviews were conducted in the participant’s preferred language (English, Luganda, Lugbara, Lugisu, or Swahili) using trained research assistants (RAs) and were recorded, transcribed verbatim, and thematically analyzed using the socioecological framework (SEM) to capture individual, interpersonal, community, and systemic-level barriers to HF care.Findings revealed a total of 11 themes spread …

Tigit And Gdf-15 As Biomarkers And Targets In Renal Cell Carcinoma Resistant To Immune Checkpoint Inhibitors, Oscar Norberto Perales

Yale Medicine Thesis Digital Library

Immune checkpoint inhibitors have become the standard of care treatment for local and systemic clear cell renal cell carcinoma (RCC). However, a subset of patients fail these therapies due to the development of disease refractory to such treatments. Therefore, it is imperative that we study the potential mechanisms of resistance to immune checkpoint inhibition within the tumor microenvironment. Likewise, establishing biomarkers indicative of treatment resistance may benefit clinicians and patients when it comes to the initial selection of treatment. Moreover, biomarkers of resistance might also serve as potential drug targets. In this study we analyzed expression of TIGIT and GDF-15, …

Cutaneous Fungal Infections In The United States: A Cross-Sectional Analysis Of National Surveys, Sarah Lee Spaulding

Yale Medicine Thesis Digital Library

Superficial cutaneous fungal infections (SCFIs), caused by yeasts, dermatophytes, and nondermatophyte molds, are prevalent skin conditions with substantial economic and quality-of-life implications. This study aimed to evaluate trends in the prevalence of SCFIs in the United States between 2005 and 2016, using data from the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS).We performed a cross-sectional analysis of outpatient visits with SCFIs diagnoses, identified through the International Classification of Diseases, Ninth and Tenth Revisions, Clinical Modification (ICD-9-CM and ICD-10-CM). Diagnoses included conditions such as tinea unguium, tinea pedis, and candidiasis of the skin …

Macrophage Migration Inhibitory Factor And D-Dopachrome Tautomerase As Biomarkers And Key Modulators Of Tumor Progression In Head And Neck Cancer And Melanoma, Caroline Naomi Valdez

Yale Medicine Thesis Digital Library

Macrophage Migration Inhibitory Factor (MIF) and its homolog D-dopachrome Tautomerase (DDT) are pro-inflammatory cytokines implicated in tumor progression across multiple cancers. Both MIF and DDT act through canonical CD74 and non-canonical CXCR2/4/7 signaling pathways, which contribute to immune suppression and tumor progression. Elevated MIF levels are associated with metastasis and poor prognosis in HNC and contribute to immune checkpoint inhibitor (ICI) resistance in melanoma. DDT’s role in cancer is not well understood. This study aims to evaluate the expression and therapeutic potential of MIF and DDT inhibition, focusing on their ability to modulate immune responses and improve survival outcomes as …

Repressed Memories And The Body Keeps The Score: Public Perceptions And Prevalence, Kris-Ann S. Anderson, Quincy C. Miller, Deryn Strange, Kamala London

Publications and Research

The “memory wars” resurgence has renewed debates over the validity of repressed memories. This revival appears linked to factors such as changing statutes of limitations, confusion about repression, and unchallenged social media content. In a nationally representative online survey of American adults (N = 1581), we examined (a) beliefs in repression and the body keeps the score, (b) the prevalence of recovered memory claims, and (c) the impact of question phrasing on recovered memory reporting. An overwhelming 94% of respondents expressed belief in repressed memory, and 77% endorsed the idea that the body keeps the score. Additionally, 3.6% (n = …

Correlating Csr Theory And Soil Texture To Bridge The Gap In Ecological Planting Strategies For Landscape Architecture, James E. Theiss

Landscape Architecture Masters & Design Theses - Archive

Many studies are focused on the benefits of including natural and ecoregional landscape design within urban habitats; however, a focused approach to how landscape architects can begin including ecological applications within their planting designs has not been fully assessed. Once the knowledge gap between ecology and how landscape architects plan landscape plantings is fully realized, research on the benefits of bringing nature back to urban environments can be thoroughly assessed. It is common knowledge that landscape design involves creating aesthetically pleasing plant combinations based on simple site characteristics that can influence how a plant grows (Tabassum S. et al., 2020; …

Breathing New Life Into Main Street Garden: A Design To Showcase Native Forb Flowering Lawns For A More Sustainable Downtown Dallas, Tx, Peter E. Wagner

Landscape Architecture Masters & Design Theses - Archive

Lawns are a landscape staple that dominate urban and suburban spaces. While they are often criticized, for many good reasons, their general popularity and acceptance are undeniable. Aesthetic preference, simple maintenance, low upfront cost, and high recreational value make lawns a ubiquitous feature in urban design (Ignatieva et al., 2017). However, from an environmental standpoint they are immensely costly and contribute significantly to pollution (Smetana & Crittenden 2014). Ecologically speaking, they contribute very little to local biomes and, with their prevalence in rural and suburban settings, they displace large swaths of native habitat. Despite rigorous research and well-articulated arguments against …

Implementing The Gad-7 Screening Tool In An Adult Outpatient Psychiatric Clinic, Elizabath George

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Abstract

Background: Anxiety disorders are among the leading causes of disability worldwide and the most prevalent mental illness in the United States. Despite affecting 6.8 million adults annually, fewer than half with Generalized Anxiety Disorder (GAD) receive treatment. Many patients present with somatic complaints, leading to underdetection. Standardized screening tools such as the Generalized Anxiety Disorder-7 item (GAD-7) can improve identification and outcomes.

Purpose: This quality improvement (QI) project implemented the GAD-7 screening tool in an adult outpatient psychiatric clinic in North Texas and evaluated its impact on identifying patients with GAD, compared to the prior year without structured screening. …

Portable Magnetic Resonance Imaging Safety, Comfort, And Compatibility With Mobile Vehicular Platforms, Jacob Howard

Yale Medicine Thesis Digital Library

Magnetic Resonance Imaging (MRI) has evolved rapidly since its early days of imaging vials of water and mice when it was known as “zeugmatography”. As advancements in semiconductors increase computational power and algorithmic techniques stretch what we can do with this power, MRI capability is advancing beyond the conventional restraints of room-bound scanners. Low-field magnetic resonance imaging (LF-MRI) that utilizes magnets typically 1/10th the size of traditional magnets has opened the door to mobilizing this imaging modality and increased flexibility in scanner design. With these developments, a new generation of portable MRI (pMRI) is beginning its use in the hospital …

Investigating The Role Of Fnci-1 In The Development And Function Of The C. Elegans Nervous System, Meagan Collins

Open Access Master's Theses

Fanconi Anemia (FA) is a rare human genetic disease caused by mutation of any of twenty-three genes on the FA pathway, which functions in the repair of DNA damage and the maintenance of genome stability. FA is clinically characterized by congenital abnormalities and a predisposition to aplastic anemia and malignancies. Recently, progressive neurological symptoms and abnormal neurological findings on imaging have been noted in FA patients, including cerebral and cerebellar lesions, calcification, necrosis, gliosis, and associated acute and chronic neurological symptoms; this constellation of symptoms has been termed Fanconi Anemia-Associated Neurological Syndrome (FANS).

To elucidate the molecular etiology of FANS, …

Fire District Impacts On Coastal Access In Rhode Island, Annie Longo

Open Access Master's Theses

There are forty-two fire districts in the coastal state of Rhode Island, nine of which are now archaically named, as they no longer provide firefighting services nor have any firefighting responsibilities. Weekapaug, Watch Hill, and Bonnet Shores fire districts are three coastal fire districts that are uninvolved with fire suppression generally, aside from the occasional bonfire permit or fireworks show. Fire districts are quasi-public entities with taxing authorities and land ownership capabilities that act as the “keepers” of many miles of pristine coastline, instead of strictly as fire departments. The actions of these fire districts often conflict with coastal access …

Metabarcoding-Biomass Relationships And Internal Standards For Quantitative Dna Metabarcoding, Frances Webber

Open Access Master's Theses

DNA metabarcoding has been widely adopted due to its power in investigating the composition of protistan communities, accurately identifying even small and cryptic taxa. However, the compositional nature of DNA metabarcoding results, and the distortion of natural abundances due to variation of the often-used 18S rRNA gene copy number over several orders of magnitude, renders these results semi-quantitative at best, limiting the application of DNA metabarcoding to ecological study. Here, we constructed mock communities from uni-algal cultures of taxonomically diverse phytoplankton and conducted metabarcoding using multiple primer sets and both DNA and cDNA as PCR templates. For each culture, chlorophyll …

Finite Element Modeling Of Offshore Wind Monopile Impact Pile Driving In Comsol Multiphysics, Brendan J. Giordano

Open Access Master's Theses

The primary foundation type for offshore wind farms are large-diameter monopiles, which are installed with an impact hammer that produces a high-intensity, broadband impulsive signal that radiates acoustic energy in the water column and seafloor. This signal generates multiple waves such as compressional, shear and Scholte (or interface) waves. Scholte waves travel on the water-sediment interface and contain high-intensity, low-frequency energy that benthic species of fish and invertebrates could possibly detect. COMSOL Multiphysics, which is a finite element modeling software, was used to develop two transient models of impact pile driving to measure Scholte wave particle motion (displacement, velocity, acceleration) …

Association Between Vitamin D Status And Cortisol Concentration Among Pregnant Women, Kenneth Addae

Open Access Master's Theses

Objective: Vitamin D deficiency (VDD) and high circulating cortisol during pregnancy have each been linked to adverse maternal and child outcomes such as preterm birth. However, limited research has explored the association between vitamin D status and cortisol concentration during pregnancy. Our objective for this study was to determine the association between vitamin D status and cortisol concentration among pregnant women.

Methods: The Prenatal Health and Nutrition (PHAN) study was a pilot cross-sectional study of 30 healthy pregnant women conducted in targeted areas in Rhode Island. Data was collected on sociodemographic characteristics, substance use, perceived stress scale, household food security, …

Beyond A Boundary Of Systemic Anti-Black Racism In The Workplace In Canada, Adelle Blackett

Dalhousie Law Journal

In this lecture, I will, however, focus on one of the legacies of slavery, that is, the largely untold story of racial segregation in the world of work in Canada. We have come so effectively, and rightly, to focus on the effects of discrimination, that we may have inadvertently walked past the history. Reclaiming this history will comprise the first part of my talk.

The second part of my talk will reference the emergence of the duty of fair representation. I will seek to illustrate the weight of the erasure of anti-Black racism through this duty. In other words, far …

Impact Of Adverse Childhood Experiences And Hostile Attribution On Adult Romantic Relationship Dynamics, Richeila Lora

Open Access Master's Theses

The purpose of this study was to examine whether experiencing ACEs and hostile attributions led to engaging in conflict behaviors in adult romantic relationships. Additionally, it was examined whether hostile attributions served as a moderator in the relationship between experiencing ACEs and engaging in conflict behaviors. Participants were adults (N = 3.684) from the German Family Panel dataset. Structural equation modeling was used to examine the associations between experiencing ACEs, hostile attributions, and conflict behaviors. It was found that both experiencing ACEs and hostile attributions were related to engaging in conflict behaviors. However, hostile attributions did not serve as …

Herbivore Kairomones Affect Germination Speed, Seedling Growth, And Herbivory, Brooke Pellegrini

Open Access Master's Theses

Seeds and seedlings are particularly vulnerable to herbivory. Unlike mature plants, which can wait until herbivory is experienced to induce defense, seeds and seedlings face mortality if they wait. Slug mucus functions as a kairomone, a non-attack-related substance emitted by consumers that is detected by a prey species (in this case, plants). While snail mucus has been shown to induce defense in seedlings, it is not widely confirmed whether slugs have the same effect and whether seeds can also detect and react to such herbivore cues. We investigated how exposure to Arion subfuscus mucus affected growth and defense in Brassica …

Field Performance Evaluation Of Selectively Bred Eastern Oyster Lines In New Jersey And Rhode Island, Seraphina Satkowski

Open Access Master's Theses

Eastern oyster aquaculture has increased steadily over the last three decades, but the industry has yet to achieve its full potential. In the Northeast USA, production is limited in part by a lack of high performing stocks suited to the geographically broad and heterogenous growing environments. For this study, hatchery lines from Maine, New York, and New Jersey as well as crosses between each hatchery line and the selectively bred Northeast high survival (NEHÒ) line, were deployed at oyster farms in Rhode Island and New Jersey for performance evaluation. Replicate bags of each line were stocked and maintained according to …

You’Re Too Slow! Self-Selected Volitional Efforts Reveal Unexploited Neuromuscular Reserve Capacity Compared To Maximal Efforts During Fatiguing, Load Equated Resistance Exercise, Brian Benitez

Theses and Dissertations--Kinesiology and Health Promotion

This investigation examined how movement intent influences neuromuscular excitation strategies during fatiguing resistance exercise, comparing maximal intended concentric efforts versus self-selected volitional efforts during load-equated Smith machine back squat exercise to quantify reserve capacity and characterize underlying neuromuscular mechanisms. Twenty-three resistance-trained participants (12 males, 11 females) completed a repeated-measures design, with replication, across six visits, performing smith machine back squat repetitions-to-failure at 70% 1RM under maximal intent (accelerate rapidly) and volitional intent (self-selected effort) conditions. Maximal voluntary isometric contractions used rapid (instantaneous 10-second effort) and ramp (5-second build-up, 5-second maximal) protocols. Surface electromyography (sEMG) was recorded from vastus lateralis and …

Bridging Awareness And Access: Outdoor Recreation And Physical Activity In Eastern Kentucky, Timothy Mckay

Theses and Dissertations--Kinesiology and Health Promotion

Physical inactivity remains a pressing challenge in Appalachian Kentucky, where high obesity rates intersect with limited access to structured exercise facilities. This dissertation investigated the extent to which participation in outdoor recreation supports adherence to physical activity (PA) recommendations and explored community awareness of local public lands. Surveys from 52 adult participants in Knox County revealed strong engagement in outdoor activity, with participation significantly predicting compliance with national PA guidelines. Educational attainment was also associated with higher rates of PA compliance, pointing to the influence of literacy and awareness in health behaviors. Reliability testing of the Outdoor Physical Activity Attitude …