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Full-Text Articles in Entire DC Network
The Utah Statesman, January 27, 2025, Utah State University
The Utah Statesman, January 27, 2025, Utah State University
The Utah Statesman
Weekly student newspaper of Utah State University in Logan.
From Dixie To Rocky Top: Music And Meaning In Southeastern Conference Football, Ariana Baker
From Dixie To Rocky Top: Music And Meaning In Southeastern Conference Football, Ariana Baker
The Southeastern Librarian
Carrie Tipton Nashville: Vanderbilt University Press, 2023 ISBN: 9780826506399 320 p. $34.95 (Pbk)
News From The States
The Southeastern Librarian
News from participating Southeastern states.
Plants, Protests, Pachakuti: How Trees March And How People Tree, Ashley A. Lundquist
Plants, Protests, Pachakuti: How Trees March And How People Tree, Ashley A. Lundquist
Theses and Dissertations
This thesis explores the multi-faceted role of plants, specifically Wituk and Manduru, in Amazonian protests and environmental advocacy. By examining the communicative and relational ontologies inherent in Runa culture, the study elucidates how plants influence social movements and contribute to environmental protection. Wituk and Manduru create paint. Paint facilitates good communication which creates good relationality. Good relationality allows for increased capacities and inhibits greedy consumption allowing for a balanced world order. Through the use and agency of Wituk and Manduru, movements become multi-species phenomena in which ecological entities combine with Runa bodies. The relationships shared between Runa, Wituk, and Manduru …
Student Senate Meeting Minutes January 27, 2025, Student Senate-Winona State University
Student Senate Meeting Minutes January 27, 2025, Student Senate-Winona State University
Student Senate Meeting Minutes
This document is the official Winona State University Student Senate Minutes for January 27, 2025.
Bespoke Regulation Of Artificial Intelligence, Brenda M. Simon
Bespoke Regulation Of Artificial Intelligence, Brenda M. Simon
Loyola of Los Angeles Law Review
The decision to regulate artificial intelligence (AI) has far reaching consequences. Determining how to address budding applications of AI technology should depend on their effects. This article describes how regulation should be carefully tailored to avoid harm while maximizing social welfare, building on Orly Lobel’s taxonomy of regulatory tools. Part I examines the foundational difficulties in governing AI, including industry influence in regulation and deficiencies in enforcement. Part II elaborates on Lobel’s framework, detailing the benefits and limitations of a variety of tools, such as voluntary standards, soft law mechanisms, and public-private partnerships. It describes how bringing in diverse stakeholders …
Prison Capital: Mass Incarceration And Struggles For Abolition Democracy In Louisiana, Tim Dodge
Prison Capital: Mass Incarceration And Struggles For Abolition Democracy In Louisiana, Tim Dodge
The Southeastern Librarian
Lydia Pelot-Hobbs Chapel Hill: University of North Carolina Press, 2023 ISBN: 97814696775114 374 p. $29.95 (Pbk)
Selling Science Fiction Cinema: Making And Marketing A Genre, Camille Mccutcheon
Selling Science Fiction Cinema: Making And Marketing A Genre, Camille Mccutcheon
The Southeastern Librarian
J.P. Telotte Austin: University of Texas Press, 2023 ISBN: 9781477327333 192 p. $45.00 (Hbk)
The Diamond, January 27, 2025, Dordt University
The Diamond, January 27, 2025, Dordt University
Dordt Diamond
- Front Page: Sioux Center Receives $9,300 Tourism Grant for Website; Dordt University Announces New Leadership in Cabinet as John Baas Steps Down; Until All Is Made New: Dordt University's Directional Vision Displayed in New Tagline
- News: A City in Ashes: A Look at the Wake of L.A. Area Wildfires; Dordt Student Pulls Some Strings for Dordt University's First Archery Club; Defender Athletics Sponsored by Nike Inc.; Dr. Rose Passes the Orchestra Baton to Mrs. Smit
- Feature: AMOR 2024: Making Connections in Nicaragua; Dr. David J. Mulder: "Always Becoming, Never Arriving"; Republicans Club Seeks to Renew Political Discussion …
Chemotherapy In Synergy With Innate Immune Agonists Enhances T Cell Priming For Checkpoint Inhibitor Treatment In Pancreatic Cancer, Nan Niu, Keyu Li, Junke Wang, Vanessa Funes, Birginia Espinoza, Pan Li, Jianxin Wang, Melissa Lyman, Mengni He, Brian Herbst, Michael Wichroski, Ruslan Novosiadly, Sami Shoucair, Yiping Mou, Lei Zheng
Chemotherapy In Synergy With Innate Immune Agonists Enhances T Cell Priming For Checkpoint Inhibitor Treatment In Pancreatic Cancer, Nan Niu, Keyu Li, Junke Wang, Vanessa Funes, Birginia Espinoza, Pan Li, Jianxin Wang, Melissa Lyman, Mengni He, Brian Herbst, Michael Wichroski, Ruslan Novosiadly, Sami Shoucair, Yiping Mou, Lei Zheng
Faculty, Staff and Student Publications
Background: The combination of conventional chemotherapy and immune checkpoint inhibitors (ICIs) has been unsuccessful for pancreatic ductal adenocarcinoma (PDAC). Administration of maximum tolerated dose of chemotherapy drugs may have immunosuppressive effects.
Methods: We thus tested, by using the preclinical model of PDACs including the genetically engineered mouse KPC spontaneous pancreatic tumor model and the pancreatic KPC tumor orthotopic implant model, the combinations of synthetic innate immune agonists including STING and NLRP3 agonist, respectively, and ICIs with or without chemotherapy.
Results: We found that innate agonists potentiate the role of chemotherapy in inducing effector T cells and subsequently to prime the …
Comparison Of Milling Cutting Forces In Synthetic And Biological Cancellous Bone, Matthew Christopher Hartwell
Comparison Of Milling Cutting Forces In Synthetic And Biological Cancellous Bone, Matthew Christopher Hartwell
Masters Theses
In many orthopedic and dental interventions, the cutting and removal of bone is necessary. Therefore, it is of the utmost importance that the tools used during these procedures are designed and tested with biological bone or a bone surrogate material that machines the same way as biological bone. To avoid the cost, hazard, and inconsistency of biological cadaveric bone or animal models, many biological engineering firms use bone surrogate material made of glass fiber filled epoxy and polyurethane foam. Although these materials may mimic the elongation of cortical and cancellous bone, respectively, the match of machinability of the bone is …
Tfap2e Is Implicated In Central Nervous System, Orofacial And Maxillofacial Anomalies, Jeshurun C Kalanithy, Enrico Mingardo, Jil D Stegmann, Ramgopal Dhakar, Tikam Chand Dakal, Jill A Rosenfeld, Wen-Hann Tan, Stephanie A Coury, Audrey C Woerner, Jessica Sebastian, Paul A Levy, Leah R Fleming, Lea Waffenschmidt, Tobias T Lindenberg, Öznur Yilmaz, Khadija Channab, Bimaljeet K Babra, Andrea Christ, Britta Eiberger, Selina Hölzel, Clara Vidic, Felix Häberlein, Nina Ishorst, Juan E Rodriguez-Gatica, Behnaz Pezeshkpoor, Patrick A Kupczyk, Olivier M Vanakker, Sara Loddo, Antonio Novelli, Maria L Dentici, Albert Becker, Holger Thiele, Jennifer E Posey, James R Lupski, Alina C Hilger, Heiko M Reutter, Waltraut M Merz, Gabriel C Dworschak, Benjamin Odermatt
Tfap2e Is Implicated In Central Nervous System, Orofacial And Maxillofacial Anomalies, Jeshurun C Kalanithy, Enrico Mingardo, Jil D Stegmann, Ramgopal Dhakar, Tikam Chand Dakal, Jill A Rosenfeld, Wen-Hann Tan, Stephanie A Coury, Audrey C Woerner, Jessica Sebastian, Paul A Levy, Leah R Fleming, Lea Waffenschmidt, Tobias T Lindenberg, Öznur Yilmaz, Khadija Channab, Bimaljeet K Babra, Andrea Christ, Britta Eiberger, Selina Hölzel, Clara Vidic, Felix Häberlein, Nina Ishorst, Juan E Rodriguez-Gatica, Behnaz Pezeshkpoor, Patrick A Kupczyk, Olivier M Vanakker, Sara Loddo, Antonio Novelli, Maria L Dentici, Albert Becker, Holger Thiele, Jennifer E Posey, James R Lupski, Alina C Hilger, Heiko M Reutter, Waltraut M Merz, Gabriel C Dworschak, Benjamin Odermatt
Faculty, Staff and Students Publications
Background: Previous studies in mouse, Xenopus and zebrafish embryos show strong tfap2e expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in neural crest specification. However, the role of human transcription factor activator protein 2 (TFAP2E) in human embryonic central nervous system (CNS), orofacial and maxillofacial development is unknown.
Methods: Through a collaborative work, exome survey was performed in families with congenital CNS, orofacial and maxillofacial anomalies. Exome variant prioritisation prompted TFAP2E gene for functional analysis in zebrafish embryos. Embryonic morphology and development were assessed after antisense morpholino (MO) knockdown (KD), CRISPR/Cas9 knockout and overexpression …
Immuno-Bioinformatics Study Of Secondary Metabolites From Watercress Nasturtium Officinale As Immunostimulant In Whiteleg Shrimp Litopenaeus Vannamei By Targeting Peroxinectin And Scavenger Receptor Class B, Qurrota A’Yunin, Muhaimin Rifa’I, Maftuch Maftuch, Yoga Dwi Jatmiko, Muhammad Hermawan Widyananda, Triyanto Triyanto, Muhammad Tegar Handrianto
Immuno-Bioinformatics Study Of Secondary Metabolites From Watercress Nasturtium Officinale As Immunostimulant In Whiteleg Shrimp Litopenaeus Vannamei By Targeting Peroxinectin And Scavenger Receptor Class B, Qurrota A’Yunin, Muhaimin Rifa’I, Maftuch Maftuch, Yoga Dwi Jatmiko, Muhammad Hermawan Widyananda, Triyanto Triyanto, Muhammad Tegar Handrianto
Karbala International Journal of Modern Science
The viral disease affects the whiteleg shrimp (Litopenaeus vannamei) and causes losses. Immunostimulants are recognized as a more environmentally friendly approach to disease management and antimicrobial properties of aquatic organisms. Watercress (Nasturtium officinale) is an aquatic plant species that contains antioxidant properties that can protect the organism from disease and boost the immune system. Shrimp rely heavily on innate immunity to combat infectious agents due to their absence of adaptive immunity. Peroxinectin and scavenger receptor class B (SRB) play essential roles in the shrimp defense system. This research employs a bioinformatic to assess the immunostimulatory potential …
Disrupting Creativity: Copyright Law In The Age Of Generative Artifical Intelligence, Ryan Abbott, Elizabeth Rothman
Disrupting Creativity: Copyright Law In The Age Of Generative Artifical Intelligence, Ryan Abbott, Elizabeth Rothman
Florida Law Review
Over the last few years, due largely to breakthroughs in deep learning technologies, artificial intelligence (AI) has begun to step into the shoes of human content generators and make valuable creative works at scale. Before the end of the decade, a significant amount of art, literature, music, software, and web content will likely be created by AI rather than traditional human authors. Yet the law lags behind this technological evolution by prohibiting copyright protection for AI-generated works. The predominant narrative holds that even if AI can automate creativity, this activity is not the right sort of thing to protect, and …
Deconstructing Employment Contract Law, Rachel Arnow-Richman, J. H. Verkerke
Deconstructing Employment Contract Law, Rachel Arnow-Richman, J. H. Verkerke
Florida Law Review
Employment contract law is an antiquated, ill-fitting, incoherent mess. But no one seems inclined to fix this problem. Employment law scholars, skeptical of employees’ ability to bargain, tend to disregard contract law and advocate for just-cause and other legislative reforms to eliminate at-will employment. And contracts scholars largely ignore employment cases—viewing them, with some justification, as part of a peculiar, specialized body of law wholly divorced from general contract jurisprudence. As a result of this undesirable employment law exceptionalism, courts lack the tools needed to resolve recurring disputes. This Article offers a new, comprehensive historical account that exposes the formalistic …
Presuming Trustworthiness, Ronnell Andersen Jones, Sonja R. West
Presuming Trustworthiness, Ronnell Andersen Jones, Sonja R. West
Florida Law Review
A half-century ago, the U.S. Supreme Court often praised speakers performing the press function. While the Justices acknowledged that press reports are sometimes inaccurate and that media motivations are at times less than public-serving, their laudatory statements nonetheless embraced a baseline presumption of the value and trustworthiness of press speech in general. Speech in the exercise of the press function, they told us, is vitally important to public discourse in a democracy and therefore worthy of protection even when it falls short of the ideal in a given instance. Those days are over. Our study of every reference to the …
State Power And Anticompetitive Conduct, Gregory Day
State Power And Anticompetitive Conduct, Gregory Day
Florida Law Review
States can and do suppress competition when it harms marginalized communities. For example, states have monopolized prison markets, forcing society’s least powerful to pay high prices for medicine, snacks, and other goods. It is also common for states to organize licensing agencies who can protect incumbent interests by refusing to grant licenses to immigrant entrepreneurs such as African hair braiders, street vendors, and more. From current and historical perspectives, anticompetitive practices have quietly entailed one of the most effective methods of oppressing marginalized people. That said, states are exempted from antitrust review due to federalism, which concerns constitutional power sharing …
Personal Jurisdiction's Moment Of Opportunity: A Reform Blueprint For Originalists And Nonoriginalists, Allan Erbsen
Personal Jurisdiction's Moment Of Opportunity: A Reform Blueprint For Originalists And Nonoriginalists, Allan Erbsen
Florida Law Review
Personal jurisdiction doctrine is broken, but there is a moment of opportunity to repair it. The Supreme Court has struggled for decades to explain why constitutional law sometimes prevents states from providing local remedies for local injuries. Basic questions lack satisfying answers. Should doctrine emphasize liberty or federalism? Is the Due Process Clause the proper foundation for limits on state power or are other clauses more relevant? What harms should limits on state power prevent and what harms should limits avoid creating? Decisions addressing these questions rely on jargon rather than a coherent account of how to allocate jurisdictional power …
André Is An Idiot, John C. Lyden
André Is An Idiot, John C. Lyden
Journal of Religion & Film
This is a film review of André is an Idiot (2025), directed by Tony Benna.
Influence Of High Eimeria Tenella Immunization Dosages On Total Oocyst Output And Specific Antibodies Recognition Response In Hybrid Pullets (Gallus Gallus)-A Pilot Study, Marco A. Juarez-Estrada, Guillermo Tellez-Isaias, Victor M. Petrone-Garcia, Amanda Gayosso-Vazquez, Xochitl Hernandez-Velasco, Rogelio A. Alonso-Morales
Influence Of High Eimeria Tenella Immunization Dosages On Total Oocyst Output And Specific Antibodies Recognition Response In Hybrid Pullets (Gallus Gallus)-A Pilot Study, Marco A. Juarez-Estrada, Guillermo Tellez-Isaias, Victor M. Petrone-Garcia, Amanda Gayosso-Vazquez, Xochitl Hernandez-Velasco, Rogelio A. Alonso-Morales
Political Science Faculty Publications and Presentations
Background: Two high primary-immunization doses of a wild-type E. tenella strain were assessed in healthy pullets (5K versus 10K sporulated oocysts/bird) to understand the effects of coccidia infection. Methods: Acquired immunity was evaluated following primary immunization and two booster doses with the homologous strain. Total oocyst shedding, clinical signs, and viability of every bird/group after each immunization/booster were recorded. Indirect ELISA measured the time course of humoral responses from each immunization group against sporozoite and second-generation merozoite of E. tenella. Antigen pattern recognition on these two asexual zoite stages of E. tenella was analyzed using Western blotting with antibodies from …
Sigma1 Inhibitor Suppression Of Adaptive Immune Resistance Mechanisms Mediated By Cancer Cell Derived Extracellular Vesicles, Paola A. Castagnino, Derick A. Haas, Luca Musante, Nathalia A. Tancler, Bach V. Tran, Rhonda Kean, Alexandra R. Steck, Luis A. Martinez, Elahe A. Mostaghel, D. Craig Hooper, Felix J. Kim
Sigma1 Inhibitor Suppression Of Adaptive Immune Resistance Mechanisms Mediated By Cancer Cell Derived Extracellular Vesicles, Paola A. Castagnino, Derick A. Haas, Luca Musante, Nathalia A. Tancler, Bach V. Tran, Rhonda Kean, Alexandra R. Steck, Luis A. Martinez, Elahe A. Mostaghel, D. Craig Hooper, Felix J. Kim
Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers
Adaptive immune resistance in cancer describes the various mechanisms by which tumors adapt to evade anti-tumor immune responses. IFN-γ induction of programmed death-ligand 1 (PD-L1) was the first defined and validated adaptive immune resistance mechanism. The endoplasmic reticulum (ER) is central to adaptive immune resistance as immune modulatory secreted and integral membrane proteins are dependent on ER. Sigma1 is a unique ligand-regulated integral membrane scaffolding protein enriched in the ER of cancer cells. PD-L1 is an integral membrane glycoprotein that is translated into the ER and processed through the cellular secretory pathway. At the cell surface, PD-L1 is an immune …
Genome-Wide Profiling Of Trna Modifications By Induro-Trnaseq Reveals Coordinated Changes, Yuko Nakano, Howard Gamper, Henri Mcguigan, Sunita Maharjan, Jiatong Li, Zhiyi Sun, Erbay Yigit, Sebastian Grünberg, Keerthana Krishnan, Nan-Sheng Li, Joseph Piccirilli, Ralph Kleiner, Nicole Nichols, Brian Gregory, Ya-Ming Hou
Genome-Wide Profiling Of Trna Modifications By Induro-Trnaseq Reveals Coordinated Changes, Yuko Nakano, Howard Gamper, Henri Mcguigan, Sunita Maharjan, Jiatong Li, Zhiyi Sun, Erbay Yigit, Sebastian Grünberg, Keerthana Krishnan, Nan-Sheng Li, Joseph Piccirilli, Ralph Kleiner, Nicole Nichols, Brian Gregory, Ya-Ming Hou
Department of Biochemistry and Molecular Biology Faculty Papers
While all native tRNAs undergo extensive post-transcriptional modifications as a mechanism to regulate gene expression, mapping these modifications remains challenging. The critical barrier is the difficulty of readthrough of modifications by reverse transcriptases (RTs). Here we use Induro-a new group-II intron-encoded RT-to map and quantify genome-wide tRNA modifications in Induro-tRNAseq. We show that Induro progressively increases readthrough over time by selectively overcoming RT stops without altering the misincorporation frequency. In a parallel analysis of Induro vs. a related RT, we provide comparative datasets to facilitate the prediction of each modification. We assess tRNA modifications across five human cell lines and …
Development And Characterization Of Cd44-Targeted X-Aptamers With Enhanced Binding Affinity For Cancer Therapeutics, Hongyu Wang, Weiguo He, Miguel-Angel Elizondo-Riojas, Xiaobo Zhou, Tae Jin Lee, David G Gorenstein
Development And Characterization Of Cd44-Targeted X-Aptamers With Enhanced Binding Affinity For Cancer Therapeutics, Hongyu Wang, Weiguo He, Miguel-Angel Elizondo-Riojas, Xiaobo Zhou, Tae Jin Lee, David G Gorenstein
Faculty, Staff and Student Publications
CD44, a pivotal cell surface molecule, plays a crucial role in many cellular functions, including cell-cell interactions, adhesion, and migration. It serves as a receptor for hyaluronic acid and is involved in lymphocyte activation, recirculation, homing, and hematopoiesis. Moreover, CD44 is a commonly used cancer stem cell marker associated with tumor progression and metastasis. The development of CD44 aptamers that specifically target CD44 can be utilized to target CD44-positive cells, including cancer stem cells, and for drug delivery. Building on the primary sequences of our previously selected thioaptamers (TAs) and observed variations, we developed a bead-based X-aptamer (XA) library by …
The Right To Receive Information: Conceptual Problems, Shrutanjaya Bhardwaj Mr
The Right To Receive Information: Conceptual Problems, Shrutanjaya Bhardwaj Mr
Indian Journal of Law and Technology
This article studies the “right to receive information” or the “right to know”, a judicially-recognised right under Article 19(1)(a) of the Constitution. It attempts to show, through an analysis of judgments of the Supreme Court and High Courts, that the right rests on a shaky philosophical foundation and that there are inconsistencies in how the right is judicially treated in terms of its structure and content.
First, the article questions the logic that the “right to know” is implicit in Article 19(1)(a) merely because it makes the exercise of free speech more meaningful. Such a logic was authoritatively rejected by …
Social Jetlag Alters Markers Of Exercise-Induced Mitochondrial Adaptations In The Heart, Michael B. Dial, Elias M. Malek, Austin R. Cooper, Greco A. Neblina, Nikoleta I. Vasileva, Graham Mcginnis
Social Jetlag Alters Markers Of Exercise-Induced Mitochondrial Adaptations In The Heart, Michael B. Dial, Elias M. Malek, Austin R. Cooper, Greco A. Neblina, Nikoleta I. Vasileva, Graham Mcginnis
Kinesiology and Nutrition Sciences Faculty Research
Social jetlag (SJL) represents the behavioral misalignment of sleep and wake times on work days and free days, and potently disrupts the circadian rhythm. SJL affects up to 70% of the population worldwide and is associated with increased risk for many cardiometabolic diseases. Animal models of acute SJL have shown disruption in locomotor activity and expression of clock genes in select tissues, its impact on the heart remains unclear. The purpose of this study was to investigate the effects of prolonged SJL (6 weeks), on activity rhythms, and the impact on exercise-induced adaptations in the heart. Male mice (n …
Efektivitas Full Body Stretching Dan Edukasi Manual Handling Digital Terhadap Keluhan Musculoskeletal Disorders Pekerja Yantek, Nadia Rosalinda, Anita Sulistyorini, Marji Marji, Supriyadi Supriyadi, Tika Dwi Tama
Efektivitas Full Body Stretching Dan Edukasi Manual Handling Digital Terhadap Keluhan Musculoskeletal Disorders Pekerja Yantek, Nadia Rosalinda, Anita Sulistyorini, Marji Marji, Supriyadi Supriyadi, Tika Dwi Tama
National Journal of Occupational Health and Safety
Occupational Diseases (PAK) in the form of pain complaints in the skeletal system that cause the work process are called Musculoskeletal Disorders (MSDs). PT. PLN Yantek workers are at risk of experiencing MSDs complaints because the work is done manually and the work posture is less ergonomic. This study aimed to analyze the effect of implementing full-body stretch and digital-based manual handling education and to assess its effectiveness on MSDs. The study used a quasi-experimental method with a one-group pretest-posttest design involving 26 Yantek workers. The intervention was given at 10 meetings, MSDs complaints were measured using the Nordic Body …
Walking Through The Aristotelian Lane: Amartya Sen On Rational Choice, Barada Laxmi Panda
Walking Through The Aristotelian Lane: Amartya Sen On Rational Choice, Barada Laxmi Panda
Comparative Philosophy
The term ‘rational choice’ has great impact on the life of a rational agent. Rational choice helps the agent to understand her capability of making choice and the intentional involvement for working on a particular aspect considering certain circumstances. At the same time, this creates a lot of dilemmas in terms of understanding the freewill of the agent while being committed for a work. Following this, Amartya Sen’s discussion on this subject seems relevant where Sen very prominently reflects on the point that rational choice involves freedom, rationality, and normativity. These three features are coherent with each other and with …
A Constructive Dialogue Between Confucianism And Transcendentalism Of Ralph Waldo Emerson, Yuedi Liu
A Constructive Dialogue Between Confucianism And Transcendentalism Of Ralph Waldo Emerson, Yuedi Liu
Comparative Philosophy
Ralph Waldo Emerson, an American Transcendentalist, is known as “the American Confucius”. He is also deeply influenced by the Confucianism from Confucius to Mencius, moreover, there is a constructive dialogue and engagement between them. However, it can not be inferred that Confucianism is also transcendentalism. First, Confucianism is based on “One-worldness”. Second, Confucianism is a kind of Guanxi-ism (relationism), so it is not individualism. Third, Confucianism is not intuitionism, but has the“structure of emotion-reason”. Fourth, Confucianism is not focus on “Oversoul”, but towards a pan-aestheticism based on the integration of Rites and Music. However, there are many similarities between American …
The Economics And Productivity Of Us Cow-Calf Production, Richard Nehring, Hannah Shear, Kelvin L. Leibold, Andrew Swanson
The Economics And Productivity Of Us Cow-Calf Production, Richard Nehring, Hannah Shear, Kelvin L. Leibold, Andrew Swanson
Journal of Applied Farm Economics
We explore US beef cow-calf production in 2018 and estimate net returns, returns to scale, and technical efficiency associated with backgrounding versus nonbackgrounding by size and production system. We determine the relative profitability of cow-calf operations by type, region, and size. Results, using both stochastic production frontier analysis and data envelopment analysis, indicate that larger operations tend to be more scale and technically efficient than smaller operations. While larger operations may be more scale and technically efficient and have lower variable costs per cow, off-farm income helps smaller operations become competitive. The availability of detailed cost of production information in …