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2025

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Echocardiography And Heart Failure: An Echocardiographic Decision Aid For The Diagnosis And Management Of Cardiomyopathies., Ashley Pender, Jessica Lewis-Owona, Abdulmojeed Ekiyoyo, Marcus Stoddard Feb 2025

Echocardiography And Heart Failure: An Echocardiographic Decision Aid For The Diagnosis And Management Of Cardiomyopathies., Ashley Pender, Jessica Lewis-Owona, Abdulmojeed Ekiyoyo, Marcus Stoddard

Division of Cardiology Faculty Papers

PURPOSE OF REVIEW: The purpose of this review is to highlight the utility of echocardiography in the diagnosis and management of cardiomyopathies.

RECENT FINDINGS: Echocardiographic parameters function synergistically to guide decision-making ranging from early detection of disease and screening to risk stratification of complex disease. The collective wealth of information available from 2D/3D assessment, Doppler, diastology and strain makes echocardiography an invaluable decision aid.


A Qualitative Look At The Impact Of Animal-Assisted Therapy On The Lived Experiences Of Recovery Home Residents With Co-Occurring Substance Use And Mental Health Disorders, Philip M. Papoojian Feb 2025

A Qualitative Look At The Impact Of Animal-Assisted Therapy On The Lived Experiences Of Recovery Home Residents With Co-Occurring Substance Use And Mental Health Disorders, Philip M. Papoojian

Doctoral Dissertations and Projects

Animal-assisted therapy (AAT) is a commonly used intervention strategy for addressing psychiatric disorders comorbid with substance use in Europe but is a rarely used intervention in North America. As substance abuse continues to rise in contemporary Western culture, particularly in the United States, new interventions, including AAT, need to be considered. Cannabis abuse and opioid abuse are often comorbid with other psychiatric disorders such as alcoholism, general anxiety disorder, depression, bipolar disorder, schizophrenia, and PTSD. The combination of these factors can stunt developmental processes. This study was designed as a qualitative exploration of the lived experiences of male substance users …


Celtic Pagan Influence In The Early Irish Church: The Conversion Of Ulster, Cassidy M. Mcnally Feb 2025

Celtic Pagan Influence In The Early Irish Church: The Conversion Of Ulster, Cassidy M. Mcnally

Doctoral Dissertations and Projects

This dissertation explores the influence of Celtic Pagan traditions on the early Irish Church in Ulster, from the introduction of Christianity in the late fourth century to the Viking invasions of the twelfth century. By integrating historical texts, archaeological findings, and comparative religious studies, it investigates how pre-Christian beliefs and rituals were assimilated into early Christian practices. The study begins by examining the arrival of Christianity in Ulster, highlighting how Celtic Paganism, characterized by its pantheon, nature worship, and druidic traditions, shaped the Christian framework. It delves into how early Christian leaders, such St. Patrick and St. Brigid, navigated these …


A Quantitative Study: The Association Between College Selection Methodology And Sense Of Belongingness Among First-Year, Full-Time Residential College Students, Tamara Reese Feb 2025

A Quantitative Study: The Association Between College Selection Methodology And Sense Of Belongingness Among First-Year, Full-Time Residential College Students, Tamara Reese

Doctoral Dissertations and Projects

College selection methodology can be traced back to the 1920s when colleges had to rely on their to travel through word of mouth, catalogs, pictures, and brochures. Although virtual tours can be dated back to 1994, COVID-19 catapulted the popularity of traveling through virtual reality. While many studies have sought to measure the impact of visitation on student enrollment propensities, none have made a noteworthy effort to account for a potential endogenous link between the student's college choice methodology and a student's sense of belongingness at their college or university campus. The purpose of this quantitative quasi-experimental study is to …


The Differences In Perceived Stress And Coping For Prelicensure Nursing Students After A Positive Reappraisal Coping Intervention, Deanna Lynne Walborn Feb 2025

The Differences In Perceived Stress And Coping For Prelicensure Nursing Students After A Positive Reappraisal Coping Intervention, Deanna Lynne Walborn

Doctoral Dissertations and Projects

Academic stress has become a common problem among nursing students, which can lead to undesirable student outcomes if their stress goes unabated. The purpose of this quasi-experimental pretest/posttest study is to determine if an intervention using a positive reappraisal coping intervention (PRCI) can reduce student nurse stress. Knowles’ theory of adult learning along with Lazarus and Folkman’s transactional model of stress and coping (TMSC) provided a foundation for the study. Olejnik’s (1984) table was used to determine the minimal total sample size required for this research. A sample of 26 nursing students from those who are enrolled in a public …


Development Of Interactive Hologram-Based Learning Media For Physical Education Sports And Health Subjects In Elementary School, Saeldho We Lastya, Didik Rilastiyo Budi, Rifqi Festiawan, Kusnandar Kusnandar, Erwin O. Estrella, Mohammad Ashraf Khan Feb 2025

Development Of Interactive Hologram-Based Learning Media For Physical Education Sports And Health Subjects In Elementary School, Saeldho We Lastya, Didik Rilastiyo Budi, Rifqi Festiawan, Kusnandar Kusnandar, Erwin O. Estrella, Mohammad Ashraf Khan

Indonesian Journal of Research in Physical Education, Sport, and Health

Background: Physical education sports and health material sports games still use conventional methods by relying on books and other tools. Technology-based interactive media has yet to be applied to interactive learning. Objective: This study aims to produce hologram-based interactive learning media that effectively increase student knowledge. Methods: This study used the Research and Development (RnD) method. This study used a sample of 5th-grade students from State Elementary School 1 Tinggarwangi 26 students, State Elementary School 3 Jambu 16 students, and State Elementary School 1 Banteran 20 students. Research instruments for media use validation questionnaires and student and teacher assessments. Cognitive …


A New Way For Justice For Families Of Schoolchildren With Disabilities? A Case Note On Luna Perez V. Sturgis Public Schools, Kevin R. Hart Feb 2025

A New Way For Justice For Families Of Schoolchildren With Disabilities? A Case Note On Luna Perez V. Sturgis Public Schools, Kevin R. Hart

New Mexico Law Review

For years, the majority of courts have ruled that parents of children with disabilities were required to exhaust special education due process procedures before filing civil actions under other disability statutes. Change would come through Luna Perez v. Sturgis Public Schools. In Luna Perez, a deaf student, Miguel Luna Perez, was denied a free and appropriate education for eleven years. After settling the case under the Individuals with Disabilities Education Act (IDEA), Mr. Luna Perez (initially through his mother, but later continuing on his own) filed a claim for compensatory damages under the Americans with Disabilities Act (ADA) and Section …


Myelin-Reactive Cd8+ T Cells Influence Conventional Dendritic Cell Subsets Towards A Mature And Regulatory Phenotype In Experimental Autoimmune Encephalomyelitis, Mohit Upadhye, Connor R Wilhelm, Kai J Rogers, Chakrapani Vemulawada, Nicholas Borcherding, Alexander W Boyden, Kevin L Legge, Nitin J Karandikar Feb 2025

Myelin-Reactive Cd8+ T Cells Influence Conventional Dendritic Cell Subsets Towards A Mature And Regulatory Phenotype In Experimental Autoimmune Encephalomyelitis, Mohit Upadhye, Connor R Wilhelm, Kai J Rogers, Chakrapani Vemulawada, Nicholas Borcherding, Alexander W Boyden, Kevin L Legge, Nitin J Karandikar

2020-Current year OA Pubs

Multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system, is modeled in mice as experimental autoimmune encephalomyelitis (EAE). While CD4


Ai-Assisted Cultural And Creative Product Design Framework And Case Study, Daocai Han, Siow Kian Tan, Booi Chen Tan Feb 2025

Ai-Assisted Cultural And Creative Product Design Framework And Case Study, Daocai Han, Siow Kian Tan, Booi Chen Tan

International Journal of Management, Finance and Accounting

This paper presents an AI-assisted design framework for the development of cultural and creative products, using the Ya Chou Yue, a renowned artifact from the Shandong Museum, as a prototype for designing a cultural creative doll. The framework is structured around key steps: clarifying design objectives, creating a design plan, generating AI images, and revising the design plan. The final design outcome illustrates the practical application of AI in cultural product development. This study highlights both the advantages and limitations of AI technology in the design process, offering new approaches and methodologies for the cultural and creative industries. Furthermore, it …


Norovirus Co-Opts Ninj1 For Selective Protein Secretion, Jaewon Song, Wandy L Beatty, Anthony Orvedahl, Et Al. Feb 2025

Norovirus Co-Opts Ninj1 For Selective Protein Secretion, Jaewon Song, Wandy L Beatty, Anthony Orvedahl, Et Al.

2020-Current year OA Pubs

Plasma membrane rupture by Ninjurin-1 (NINJ1) executes programmed cell death, releasing large cellular damage-associated molecular patterns (DAMPs). However, the regulation and selectivity of NINJ1-mediated DAMP release remain unexplored. Here, we uncover that murine norovirus (MNoV) strategically co-opts NINJ1 to selectively release the intracellular viral protein NS1, while NINJ1-mediated plasma membrane rupture simultaneously bulk-releases various cellular DAMPs. Host caspase-3 cleaves the precursor NS1/2, leading to NS1 secretion via an unconventional pathway. An unbiased CRISPR screen identifies NINJ1 as an essential factor for NS1 secretion. During infection, NINJ1 is recruited to the viral replication site, where it oligomerizes and forms speckled bodies, …


Androgen Receptor Ubiquitination Links Kctd13 To Genitourinary Tract Defects, Ahmed Chahdi, Carolina Jorgez, Jill A Rosenfeld, Neetu Neetu, Abhishek Seth Feb 2025

Androgen Receptor Ubiquitination Links Kctd13 To Genitourinary Tract Defects, Ahmed Chahdi, Carolina Jorgez, Jill A Rosenfeld, Neetu Neetu, Abhishek Seth

Faculty, Staff and Students Publications

The potassium channel tetramerization domain containing 13 (KCTD13) protein is a substrate-specific adapter for cullin3-based E3 ubiquitin ligase. Patients with copy number variants at this locus exhibit genitourinary tract anomalies. In this study, we show that decreased androgen receptor (AR) protein level correlated with increased AR ubiquitination in the testis of Kctd13-deficient mice, suggesting that KCTD13 inhibits AR ubiquitination. KCTD13 increased CUL3-dependent AR ubiquitination but had no effect on CUL3 binding to AR, confirming the role of KCTD13 as an adaptor of CUL3 ligase. Recombinant KCTD13 directly binds to recombinant AR, and the BTB domain of KCTD13 is critical for …


Microplastics And Nanoplastics In Tea: Sources, Characteristics And Potential Impacts, Neamatollah Jaafarzadeh Haghighi Fard, Faezeh Jahedi, Andrew Turner Feb 2025

Microplastics And Nanoplastics In Tea: Sources, Characteristics And Potential Impacts, Neamatollah Jaafarzadeh Haghighi Fard, Faezeh Jahedi, Andrew Turner

School of Geography, Earth and Environmental Sciences

Recent scientific studies have raised concerns about the presence and potential impacts of microplastics and nanoplastics (MNPs) in tea-based drinks. This review critically examines publications relating to MNPs in tea, with focus on the type of sample involved, methods and techniques employed to isolate and identify MNPs, and the main qualitative and quantitative findings. Sources of MNPs in tea include production water, plastic packaging and contaminated tea leaves but the most important source is teabags when steeped in boiling water. Here, more than 109 MNPs have been reported to be released per plastic teabag. However, significant quantities of MNPs …


Spatial Patterns Of Visitor Behavior: A Case Study Of The North Carolina Zoological Park, Maurice L. Mckenzie, Keith G. Oebbage Feb 2025

Spatial Patterns Of Visitor Behavior: A Case Study Of The North Carolina Zoological Park, Maurice L. Mckenzie, Keith G. Oebbage

The Geographical Bulletin

This paper explains the spatial patterns of visitor behavior at the North Carolina Zoological Park (NCZP). The NCZP is one of the top ten tourist attractions in the state, but it is unclear what factors influence each individual's decision to visit the zoo. The research reported in this paper partially confirmed many of the theoretical expectations about visitor behavior. Based on the results of a visitor survey, the NCZP is a family attraction that caters to a largely well-educated and affluent audience. Most of those surveyed came from the nearby urban centers, while the rural counties immediately adjacent to the …


Native Texans' Perception Of Yankees, Byron D. Augustin, Dennis E. Fitzsimons Feb 2025

Native Texans' Perception Of Yankees, Byron D. Augustin, Dennis E. Fitzsimons

The Geographical Bulletin

Texas now ranks as the third most populous state in the United States. Over the past 40 years, much of the population growth can be attributed to migration from outside the state's boundaries. Not all native Texans look favorably on the new growth patterns. "Yankee" is a term which some native Texans tend to label any new resident who does not enter from Mexico. The purpose of this paper is to delineate those states which are perceived by native Texans to produce Yankees. A second goal is to provide insight into the perception that native Texans have regarding the word …


Volume 32-1 Complete Issue, C. Nicholas Raphael Feb 2025

Volume 32-1 Complete Issue, C. Nicholas Raphael

The Geographical Bulletin

Volume 32-1 Complete Issue


Shoreline Modification And Land Use Of Ford Lake, Michigan, Ashley M. Long, Gregory D. Ruhl Feb 2025

Shoreline Modification And Land Use Of Ford Lake, Michigan, Ashley M. Long, Gregory D. Ruhl

The Geographical Bulletin

Ford Lake in an 800-acre dammed reservoir on the Huron River some 35 miles west of Detroit. The 10-mile shoreline was investigated in the field as well as with the use of soil data and aerial photographs. The investigation of the shoreline reveals that shoreline erosion and mass wasting are related to high erodible soil types. The shoreline is being urbanized mainly with multifamily housing, causing a removal of the deciduous hardwood vegetation which has led to increased runoff. Shoreline owners have reinforced the shoreline to combat severe erosion. It is recommended that a reevalution be undertaken to provide development …


What Animals Do In Fall, Shan Martinez Feb 2025

What Animals Do In Fall, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


The Quiet Forest, Pam Blake Feb 2025

The Quiet Forest, Pam Blake

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


The Dark!: Wild Life In The Mysterious World Of Caves, Shan Martinez Feb 2025

The Dark!: Wild Life In The Mysterious World Of Caves, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Sleepy: Surprising Ways Animals Snooze, Leah D. Carruth Feb 2025

Sleepy: Surprising Ways Animals Snooze, Leah D. Carruth

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Nate The Great And The Star-Spangled Parrot, Jennifer Engle Feb 2025

Nate The Great And The Star-Spangled Parrot, Jennifer Engle

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


How To Love A Kitten, Jewell Fine Feb 2025

How To Love A Kitten, Jewell Fine

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Go Forth And Tell: The Life Of Augusta Baker, Librarian And Master Storyteller, Laura Baker Feb 2025

Go Forth And Tell: The Life Of Augusta Baker, Librarian And Master Storyteller, Laura Baker

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Explore Desert Habitats With Rosita, Shan Martinez Feb 2025

Explore Desert Habitats With Rosita, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Blue Whales: Nature’S Biggest Mammal, Shan Martinez Feb 2025

Blue Whales: Nature’S Biggest Mammal, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Bionic Animals, Shan Martinez Feb 2025

Bionic Animals, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Animal Superpowers!, Shan Martinez Feb 2025

Animal Superpowers!, Shan Martinez

Lorgnette: Quarterly Review of Children's and Young Adults' Books

No abstract provided.


Current Challenges And Preliminary Morphological Reassessment Of The Genus Chaerilus Simon, 1877 In China (Scorpiones: Chaerilidae), Victoria Tang Feb 2025

Current Challenges And Preliminary Morphological Reassessment Of The Genus Chaerilus Simon, 1877 In China (Scorpiones: Chaerilidae), Victoria Tang

Euscorpius

The genus Chaerilus Simon, 1877 in China is preliminarily revised on a morphological basis, derived from the available literature and newly examined specimens. The robustness of several commonly applied species-level diagnostic criteria are evaluated. Ten species are provisionally recognized for China, including one new morphospecies, Chaerilus herta sp. n., described from 9 females, 40 males, and 2 juvenile females collected in Mêdog County. The current study only reveals and resolves several most elementary issues in the taxonomy of Chinese Chaerilus. Further molecular investigations are warranted until topotypes of certain species become available.


The Dw2 Shipwreck: Evidence Of Trade With Small Vessels (Coasters) In Southern Syria And The Land Of Israel During The Late Ottoman Period /ספינה טרופה: עדות לסחר בכלי שיט קטנים בדרום סוריה ובארץ ישראל בשלהי התקופה העות'מאנית, Idit Yovel Even-Zur, Jacob Sharvit, Ofra Barkai Feb 2025

The Dw2 Shipwreck: Evidence Of Trade With Small Vessels (Coasters) In Southern Syria And The Land Of Israel During The Late Ottoman Period /ספינה טרופה: עדות לסחר בכלי שיט קטנים בדרום סוריה ובארץ ישראל בשלהי התקופה העות'מאנית, Idit Yovel Even-Zur, Jacob Sharvit, Ofra Barkai

Qadum: Journal of Excavation Reports from Israel

Three excavation seasons conducted in the southern lagoon of Dor uncovered the remains of the Dor Wreck 2 (DW2) shipwreck—a 15.5 m-long trading coaster built from poor-quality but well-preserved wood. The ship was constructed using techniques characteristic of the Mediterranean shipbuilding tradition. The hull of the ship was well-preserved, indicating it could carry up to 20 tons of cargo. However, due to the scarcity of finds, it is not possible to determine the ship’s cargo. The identified wood species suggest that the ship was constructed in western Turkey or southwestern Syria. Carbon-14 dating, combined with electrochemical analysis of the corrosion …


Unveiling Role Of Oncogenic Signalling Pathways In Complicating Breast Cancer, Acharya Balkrishna, Sagar Kumar, Rohan Malik, Kuldeep Singh Mehra, Hariom Chaturvedi, Okeshwar Okeshwar, Rashmi Mittal Feb 2025

Unveiling Role Of Oncogenic Signalling Pathways In Complicating Breast Cancer, Acharya Balkrishna, Sagar Kumar, Rohan Malik, Kuldeep Singh Mehra, Hariom Chaturvedi, Okeshwar Okeshwar, Rashmi Mittal

BioMedicine

Heterogeneous nature of breast cancer has significantly affected the overall survival, disease free survival and progression free survival amongst the diseased individuals. Metastasis of cancerous cells to distant sites including bone, lungs, liver, lymph node and others have further exhilarated the adverse effects. However, ER, PR and HER-2 are responsible for normal physiological development of women but in altered conditions they may act as initiator or progressor and so far 5 subtypes of disease have been identified. Alteration of pro-survival, pro-proliferative and anti-apoptotic pathways including JAK/STAT, MAPK,

PI3K/AkT/mTOR, NF-κB, BCL2 and several others have induced oncogenic events including epithelial-mesenchymal transition, …