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Benefits Of Animal Assisted Therapy In Pediatric Inpatient Units: A Literature Review, Logan M. Shiflett
Benefits Of Animal Assisted Therapy In Pediatric Inpatient Units: A Literature Review, Logan M. Shiflett
The Eleanor Mann School of Nursing Undergraduate Honors Theses
The purpose of this systematic review of literature was to establish if animal assisted therapy (AAT) is helpful in the reduction of stress for patients on pediatric inpatient floors. The PICOT question that led this review was: In pediatric patients, how does animal assisted therapy affect patient outcomes related to increased hospitalizations? The EBSCOhost database, as well as the Web of Science and CINAHL Complete information sources, were used to find relevant studies for this review that assessed the benefits and contraindications for AAT. Key terms such as “animal assisted therapy,” “pediatrics,” and “inpatient” were used to narrow down the …
Presumed Guilt: Epistemic Closure In Pregnancy Prosecutions, M. Eve Hanan
Presumed Guilt: Epistemic Closure In Pregnancy Prosecutions, M. Eve Hanan
Buffalo Law Review
Criminal law and reproductive justice scholars are calling attention to the increase in prosecutions for pregnancy outcomes in the United States. Trace amounts of controlled substances in newborns are prosecuted as child abuse. Miscarriages are prosecuted as illegal abortions or homicides. This area of criminal law existed side-by-side with Roe v. Wade for late-term pregnancy outcomes. The Dobbs decision has further emboldened these prosecutions by removing the protections of the Due Process Clause from the pre-viability phase of the pregnancy.
Using a case study of a woman who was pressured to plead guilty to manslaughter and sentenced to eight years …
Effects Of Maternal Overnutrition And Metabolic Challenge In Adult Life On The Histological Integrity Of The Liver And Intestinal Epithelium In Rabbits, Lucía Carolina Cano, Erika Navarrete, Pedro Medina, Juan Pablo Ochoa-Romo, Georgina Díaz, Rodrigo Montúfar-Chaveznava, Rosa María Vigueras-Villaseñor, Ivette Caldelas
Effects Of Maternal Overnutrition And Metabolic Challenge In Adult Life On The Histological Integrity Of The Liver And Intestinal Epithelium In Rabbits, Lucía Carolina Cano, Erika Navarrete, Pedro Medina, Juan Pablo Ochoa-Romo, Georgina Díaz, Rodrigo Montúfar-Chaveznava, Rosa María Vigueras-Villaseñor, Ivette Caldelas
Artículos científicos
Introduction: Maternal overnutrition during critical stages of embryonic development has been implicated as a major determinant of developmental and metabolic disturbances in offspring. Current data concerning how perinatal exposure to high-fat and high-carbohydrate diets, followed by re-exposure in adulthood (metabolic challenge), affects the metabolic regulation and structural integrity of the liver and small intestine, key organs of the gut–liver axis (GLA), are limited. Methods: Female rabbits were fed either a standard diet (SD) or a high-fat and high-carbohydrate diet (HFCD) before mating and during gestation. The offspring on postnatal day 440 were challenged with an HFCD or SD for 30 …
Modelling The Balance Axiom In Flow Theory: A Physiological And Computational Approach In Steam Education, David Antonio Rosas, Natalia Padilla-Zea, Daniel Burgos
Modelling The Balance Axiom In Flow Theory: A Physiological And Computational Approach In Steam Education, David Antonio Rosas, Natalia Padilla-Zea, Daniel Burgos
Artículos científicos
This paper addresses the axiom of balance in Flow Theory from a physiological-and-groupbased approach by a quasi-experimental study using mixed methods across two action– research cycles, each divided into pre-test, intervention, and post-test phases. The study involved 56 students in two control and two experimental groups attending robotics and design STEAM courses in natural settings, wearing Polar H10 bands. Each group participated in nine one-hour sessions, with the same instructor. While flow in control groups was measured with intuition-based teacher actions, in experimental groups the teacher received support from a synchronous physiological flow advisory system. Data from these groups were …
Leveling The Playing Field? Exploring The Moral Ambiguity Of The Private Attorney General Model, Nathan Heastie
Leveling The Playing Field? Exploring The Moral Ambiguity Of The Private Attorney General Model, Nathan Heastie
Washington and Lee Law Review Online
Johnson & Johnson’s market cap is twice the GDP of Oklahoma. So, when Oklahoma hauled Johnson & Johnson and other behemoth pharmaceutical companies into state court for their participation in the opioid epidemic, Big Pharma’s resources created a David v. Goliath situation. Against all odds, Oklahoma stood toe-to-toe with Big Pharma and brought home more than $650 million in settlement funds.
Oklahoma’s success would be otherwise impossible without the assistance of three private law firms serving the role of “private attorneys general.” The State signed contingency fee arrangements with the firms, transferring the financial burden of litigation from the State …
Uab Libraries News, 12 2025, Uab Libraries
Impact Of Thermodynamic Factors And Intrinsic Properties On Crystallization Behavior And Physical Properties Of Edible Fats, Nabila Anjum
Impact Of Thermodynamic Factors And Intrinsic Properties On Crystallization Behavior And Physical Properties Of Edible Fats, Nabila Anjum
All Graduate Theses and Dissertations, Fall 2023 to Present
Crystallization behavior of three edible fats: interesterified soybean oil (IESBO), interesterified palm olein (IEPO), and fully hydrogenated palm kernel oil (FHPKO) were explored to understand how this process is affected by different factors. The study focused on how the chemical composition of these fats affects their behavior like how much time they require to be crystallized at a certain temperature. By using different scientific methods, how quickly each fat began to crystallize and how much energy it took to start the process was measured. Among the methods used, Gompertz equation, a mathematical model, gave the most consistent and reliable results …
Implications Of The Attenuated Allee Effect On Population Dynamics, Dana Strong
Implications Of The Attenuated Allee Effect On Population Dynamics, Dana Strong
All Graduate Theses and Dissertations, Fall 2023 to Present
The Allee effect is an ecological phenomenon characterized by a per capita growth rate that increases as the population size increases in the context of low population density. The Allee effect can lead to rapid extinction events. Consequently, ecologists can attempt to control the strength of the Allee effect to help increase the population (in the case of endangered species) or decrease the population (in the case of parasites or pests).
This research aimed to study not the strength of the Allee effect, but the intensity of the Allee effect, or how rapidly cooperation between individuals causes the per capita …
Assessing The Human Health Impacts Of Nutrient-Dense Diets: Clinical Trials On Regenerative Agriculture And Protein Source, Jennifer Jensen-Cloward
Assessing The Human Health Impacts Of Nutrient-Dense Diets: Clinical Trials On Regenerative Agriculture And Protein Source, Jennifer Jensen-Cloward
All Graduate Theses and Dissertations, Fall 2023 to Present
Increasing consumer demand for sustainable, animal-friendly food options has sparked discussion about farming production practices. As more people prioritize their food choices, questions have circulated about how farming practices might impact not just the environment, but also human health. Regenerative agriculture is a farming method that has gained popularity for its potential to improve both food quality and environmental outcomes. It focuses on restoring ecosystem function, ultimately impacting the resulting nutrients in food products, and includes foods like grass-fed meat and organic produce. However, it is still unclear whether these practices make a difference in human health. This dissertation informs …
An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee
All Graduate Theses and Dissertations, Fall 2023 to Present
Virtual Reality (VR) technology is becoming more common in schools, especially for teaching and training. In this study, researchers explored how VR can help teenagers with disabilities improve their physical education skills, specifically push-ups, lunges, and jumping jacks. The participants all showed an increase in their skills and reached a high level of accuracy on every skill. The results showed that adding feedback was also necessary for some participants. Additionally, participants enjoyed using the VR equipment and showed high levels of happiness throughout the study. These findings suggested that using VR technology can be an effective way to support teenagers …
Resignificación De Estereotipos Negativos Y Construcción De Genealogías Femenino-Feministas En La Obra De María Hesse, María Dolores Clemente-Fernández
Resignificación De Estereotipos Negativos Y Construcción De Genealogías Femenino-Feministas En La Obra De María Hesse, María Dolores Clemente-Fernández
Capítulos de libros
En este texto nos aproximamos a la obra de la ilustradora española María Hesse, en concreto a sus trabajos como autora de álbumes ilustrados, en los que ha construido una multitud de personajes femeninos variados (históricos, ficticios, famosos, anónimos, mitológicos, etc.) al tiempo que homogeneizados en virtud de un estilo muy personal y reconocible, en el que prima técnicas como el gouache y la tinta, con fondos habitualmente blancos y coloridos dibujos con predominio de tonalidades suaves e importancia de la línea. En especial, nos acercaremos a su libro Malas mujeres (2022), en donde conforma toda una galería de mujeres …
Intentional Improvement Through 3d Environment Art, Samuel T. Pinnex
Intentional Improvement Through 3d Environment Art, Samuel T. Pinnex
Master of Fine Arts in Digital Media Culminating Experience
The idea of self-growth can be exciting—the thought of where one might be in the near or distant future is exhilarating. As an artist, this is even more apparent. On the other side of that coin, the realization that it is all up to you can oftentimes be overwhelming. We all want to improve, and we want our work to improve with us as a showcase of that improvement. Over the past two years, I’ve learned how valuable it is to adopt a “growth mindset”. Once I became comfortable with this idea, the responsibility for my own self-growth no longer …
The Absence Of Something: Addressing Underrepresented Lgbtqia+ Communities In Video Games Through Holistic Character Design Techniques, Lydia Myers
Master of Fine Arts in Digital Media Culminating Experience
This research identifies pain points and gaps in current LGBTQIA+ representation in the video games industry, and showcases the characters that I have created in response to those pain points. Despite the games industry representing LGBTQIA+ individuals often, certain communities under the umbrella are included less often, less accurately, and less respectfully than others. The goal of this research is to identify important considerations for respectfully portraying underrepresented queer communities in video games: specifically transgender, nonbinary, asexual, aromantic, and polyamorous communities, which are especially under-explored. My included characters were created via a holistic approach to character design. Despite my professional …
Methodologies For Generating Passive Income As A Digital Artist, Levi Stone
Methodologies For Generating Passive Income As A Digital Artist, Levi Stone
Master of Fine Arts in Digital Media Culminating Experience
This research provides an in-depth exploration of 3D workflow methodologies for digital merchants, how and why to implement them, and their correlation with passive income earnings. Digestible strategies regarding the development, packaging, marketing, and sale of assets for digital marketplaces are explored at length. Motivated by the state of the digital media industry, this research demonstrates that secondary income is possible through consistent, applied methodologies. Topics include environmental storytelling, the importance of being user friendly, material variance, and much more. The author demonstrates the impact of reframing your approach when designing products with the intention to sell, and explores the …
Ayo: A Creative Fusion Of Advertising And 3d Modeling, Onyedika Okonkwo
Ayo: A Creative Fusion Of Advertising And 3d Modeling, Onyedika Okonkwo
Master of Fine Arts in Digital Media Culminating Experience
This culminating experience project tells the story of Ayo, an original cereal mascot developed through the intersection of advertising strategy, personal storytelling, and 3D modeling. Rooted in my professional background as an art director, this project represents my transition from 2D print design to digital sculpting, blending branding principles with character-driven visual storytelling.
Ayo and the fictional cereal brand Surf ’n’ Crunch serve as a portfolio-ready advertising pitch, built through reflective practice. My creative evolution at ETSU: first attempting animation, discovering its limitations for my skillset and timeframe, and ultimately embracing 3D modeling as a medium that aligns more naturally …
Validation Of A Scoring System To Predict Difficult Laparoscopic Cholecystectomy In A Tertiary Hospital In Saudi-Arabia: A Retrospective Study, Hazem A. Megahed, Lamiaa Z. Elmoursi, Rakan A. Al-Etebi, Nawaf M. Al-Enazi, Ahmed M. Lashin, Sarah Marie, Ahmed Taki-Eldin
Validation Of A Scoring System To Predict Difficult Laparoscopic Cholecystectomy In A Tertiary Hospital In Saudi-Arabia: A Retrospective Study, Hazem A. Megahed, Lamiaa Z. Elmoursi, Rakan A. Al-Etebi, Nawaf M. Al-Enazi, Ahmed M. Lashin, Sarah Marie, Ahmed Taki-Eldin
Saudi Medical Journal
ABSTRACT Objectives: To confirm a preoperative scoring system devised by the Modified Randhawa Model. Methods: This retrospective study was performed in the period between October 2017 to October 2023 on every patients hospitalized for elective laparoscopic cholecystectomy in the Surgery Department, National Guard Hospital in Riyadh, Saudi Arabia. A preoperative scoring system, devised using the Modified Randhawa Model, was applied to each patient retrospectively. The preoperative score was compared to the intraoperative degree of difficulty. Results: The history of previous biliary inflammation, the impacted stone, the palpable gall bladder, the more gall bladder wall thickness, the higher body mass index …
Advancing Anesthesia Provider Proficiency In Airway Assessment Using Point-Of-Care Ultrasound: An Osce-Based Educational Initiative, Austin Fike, Trevor Jordan, Sam Sherrill Iii
Advancing Anesthesia Provider Proficiency In Airway Assessment Using Point-Of-Care Ultrasound: An Osce-Based Educational Initiative, Austin Fike, Trevor Jordan, Sam Sherrill Iii
Doctoral Projects
Airway management is one of the fundamental pillars of anesthesia. Traditionally, tools such as the Mallampati classification and the thyromental distance are used for airway assessment in the perioperative area. However, often, these methods fail to reliably predict difficult intubations. The use of point-of-care ultrasound (POCUS) has emerged as a valuable adjunct in airway assessment. However, a knowledge deficit exists among anesthesia providers regarding its application in airway assessments for perioperative adult patients. This doctoral project addressed the knowledge deficit in POCUS airway assessment among Certified Registered Nurse Anesthetists (CRNAs) and Student Registered Nurse Anesthetists (SRNAs) through the development and …
Fungal Biodiversity, Microbial Communities, And Ecosystem Function In Non-Perennial Streams, Charles T. Bond
Fungal Biodiversity, Microbial Communities, And Ecosystem Function In Non-Perennial Streams, Charles T. Bond
Dissertations
A global majority of steams are non-perennial, drying at some point in time and space. Despite the vital roles that fungi and other microbes play in stream ecosystems, most research on stream microbiomes comes from perennial (continuously flowing) streams. The present series of studies addresses this research gap by examining microbial community composition and function in non-perennial streams, with an emphasis on fungi. Chapter I reviews existing scientific literature on the ecological processes that shape microbiome structure and function in non-perennial streams and outlines the varieties of fungi that may live there. Chapter II uses rDNA metabarcoding to survey fungal …
The Genetic And Environmental Determinants Of Stress Resilience Across Model Systems, Carson Len Stacy
The Genetic And Environmental Determinants Of Stress Resilience Across Model Systems, Carson Len Stacy
Graduate Theses and Dissertations
Survival in fluctuating environments demands that organisms effectively anticipate and respond to future challenges. This capacity is shaped by both genetic background and environmental context. In this dissertation, I apply a population aware lens to explore how genetic diversity and environmental conditions intersect to shape stress survival. Integrating functional genomics and transcriptomics in Saccharomyces cerevisiae (brewer’s yeast) and a vertebrate (common canary) system, I dissect gene-by-environment (GE) interactions that underpin resilience. First, I move beyond a single reference genome by using a pan-genomic CRISPR knockout screen to assess osmotic stress survival across diverse S. cerevisiae isolates. This analysis reveals a …
Development And Optimization Of Moxifloxacin Solid Lipid Nanoparticles Via Double Emulsion Organic Solvent Free Technique Applying Box–Behnken Experimental Design, Esraa M. Elshazly, Mona G. Arafa, Samia A. Nour
Development And Optimization Of Moxifloxacin Solid Lipid Nanoparticles Via Double Emulsion Organic Solvent Free Technique Applying Box–Behnken Experimental Design, Esraa M. Elshazly, Mona G. Arafa, Samia A. Nour
Pharmacy
The current research proposes the preparation of Moxifloxacin-loaded solid lipid nanoparticles through a solvent-free double emulsion technique, to overcome chronic wound healing limitation. The independent variables: stearic acid, Span 80, and Tween 80 were optimized via Box–Behnken design, based on entrapment efficiency (EE%), zeta potential (ZP), and particle size (PS). To statistically optimize the formulation variables, a three-factor, three-level (3³) design involving 15 runs was employed and optimization was carried out to attain maximum EE% and ZP and minimum PS yielding an overall desirability of 0.851. Results indicated that increasing stearic acid enhanced EE%, Span 80 increase PS, and Tween …
Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel
Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel
Master's Theses
Distribution models provide a practical use case of connecting ecological niche theory with species’ occurrence and assemblages. By explicitly linking Hutchinson’s “niche space” with geographic space researchers can gain valuable information on a species’ niche characteristics and interactions, thereby informing conservation and management practices. The narrow-faced kangaroo rat (Dipodomys venustus) is a highly understudied kangaroo rat species endemic to the central coast of California and is an ideal species to explore niche theory in distribution modeling. Three subspecies are currently recognized: The Santa Cruz kangaroo rat (D. v. venustus), the elephant-eared kangaroo rat (D. v. …
Using Hydraulic And Hydrologic Modeling To Determine Scour At Toro Creek Under Climate Change Conditions, Gabriel E. Alaniz
Using Hydraulic And Hydrologic Modeling To Determine Scour At Toro Creek Under Climate Change Conditions, Gabriel E. Alaniz
Master's Theses
ABSTRACT
This study evaluates bridge scour at the Toro Creek crossing of Highway 1 in Morro Bay, California, under present conditions and future climate conditions with more frequent extreme rainfall events. California infrastructure is becoming increasingly vulnerable to extreme storm events and increased intense precipitation events brought by climate change. This analysis focuses on the calculation of scour for both the northbound and southbound spans. Highway 1 plays a vital role in California’s coastal transportation infrastructure by carrying more than 20,000 vehicles daily (Caltrans, 2017). In this thesis, a hydrological model (HEC-HMS) is used to simulate runoff under present-day and …
Self-Determination Through Children's Rights: Resisting The Paradoxical Pretext Of Parents' Rights Legislation, Jeremiah Chin
Self-Determination Through Children's Rights: Resisting The Paradoxical Pretext Of Parents' Rights Legislation, Jeremiah Chin
Washington Law Review
Washington state law balances the interests of parents and the state in education, healthcare, and the general wellbeing of children. Despite the fact that children are at the center of emerging controversies, children’s rights are rarely discussed in state legislation debating the obligations and relationships between the state of Washington and parents. In education, for example, RCW 28A.605.005 finds “[p]arents are the primary stakeholders in their children’s upbringing.” While this may be true relative to the state, it overlooks the fact that children are the primary actors, agents, and rights bearers in their own personhood. This Article therefore considers ongoing …
Combating Antimicrobial Resistance In Asia: A Comprehensive Review Of Strategic Action Plans, Policies, And The Role Of The Who, Saud Almawash
Combating Antimicrobial Resistance In Asia: A Comprehensive Review Of Strategic Action Plans, Policies, And The Role Of The Who, Saud Almawash
Saudi Medical Journal
ABSTRACT Over the past 70 years, antimicrobial resistance (AMR) has emerged as a critical public health concern in Asia. Regional challenges such as dense population, scarce resources, and diverse healthcare systems further complicate the containment efforts. To address this, Asian countries have adopted several strategies and policies. A comprehensive review of published literature was conducted to identify key policies and interventions. Findings revealed diverse approaches to AMR containment, including surveillance and monitoring systems, antibiotic stewardship programs, infection control measures, vaccination strategies, and public health awareness campaigns. However, implementation of these strategies is hindered by resource, political, and regulatory barriers. The …
Asymptomatic Cryptococcal Antigenemia: A Multi-Clinic Cross-Sectional Study On The Prevalence, Associated Factors And Predictors Of Three-Month Outcomes Among Antiretroviralnaïve And Antiretroviral-Experienced Hiv Patients In Dar Es Salaam, Tanzania, Mandela Makakala, Mukasa Mohammed, Mabula Mabelele, Kamran Hameed, Philip Adebayo
Asymptomatic Cryptococcal Antigenemia: A Multi-Clinic Cross-Sectional Study On The Prevalence, Associated Factors And Predictors Of Three-Month Outcomes Among Antiretroviralnaïve And Antiretroviral-Experienced Hiv Patients In Dar Es Salaam, Tanzania, Mandela Makakala, Mukasa Mohammed, Mabula Mabelele, Kamran Hameed, Philip Adebayo
Internal Medicine, East Africa
Background: Cryptococcal meningitis remains a leading cause of HIV/AIDS-related mortality, predominantly in Sub-Saharan Africa. Current screening and prevention efforts primarily target antiretroviral therapy (ART)-naïve patients, whereas strategies for ART-experienced individuals are less well defined.
Objectives: This study primarily aimed at determining the prevalence of asymptomatic cryptococcal antigenemia (ACA) among ART-naïve and ART-experienced patients, along with associated factors and predictors of three-month outcomes among HIV patients in three HIV clinics in Dar es Salaam, Tanzania. Secondarily, factors associated with serum cryptococcal antigen positivity in the overall study population were also assessed.
Methods: This cross-sectional clinic-based study recruited 273 HIV-positive participants (ART-naïve …
Identity And Representation In Contemporary Art: An Inclusive 400/500-Level Art History Seminar Course, Laura E. Franz
Identity And Representation In Contemporary Art: An Inclusive 400/500-Level Art History Seminar Course, Laura E. Franz
Theses
This project is an upper-level art history seminar addressing identity and representation – specifically related to race, ethnicity, gender, and sexuality – in contemporary art. Primarily a discussion-based course, the course is focused on inclusivity and is highly structured, with weekly low-stakes assignments that provide students with ample opportunities to practice engaging with academic texts. Designed for students with varying levels of academic skills, it is built around current non-academic articles that students select via an online survey. Students then “unpack” the “big ideas” in each of the four chosen non-academic articles via a cluster of academic readings and videos …
Drought, Worry, And Preparing For The Future: The Ethnopsychology Of Climate Distress In Kilifi County, Kenya, Edna Bosire, Syed Wahid, Linda Khakali, Benjamin Oestericher, Felix Agoi, Anthony Ngugi, Rosebella Iseme, Jasmit Shah, Zul Merali, Lukoye Atwoli
Drought, Worry, And Preparing For The Future: The Ethnopsychology Of Climate Distress In Kilifi County, Kenya, Edna Bosire, Syed Wahid, Linda Khakali, Benjamin Oestericher, Felix Agoi, Anthony Ngugi, Rosebella Iseme, Jasmit Shah, Zul Merali, Lukoye Atwoli
Brain and Mind Institute
The impacts of climate change in sub-Saharan Africa (SSA) presents a chronic and intensifying disaster, with drought, flooding, and extreme heat, presenting unique challenges and profound disruptions. Growing evidence links such events to ecological grief, ecological anxiety, and solastalgia – negative affective states that reflects responses to climate change related destruction of nature, species, culturally significant or sacred spaces, and other ways of life. While this literature is expanding in the Global North, little is known about how communities in SSA perceive and respond to deteriorating or depleting natural ecosystems. This article explores the ethnopsychology of distress precipitated by environmental …
Pas De Deux, Emmalea Bellemare
Pas De Deux, Emmalea Bellemare
LSU New Orleans Theses and Dissertations
In New York City, 2004, 20-year-old Michael Kurotori is a professional ballet dancer and instructor working for the prestigious Brigid Ballet Academy. Under the supervision of his mentor, Prima Ballerina Anya Vladislav, Michael is quickly approaching the top of his career - until a new student threatens to steal Anya’s attention away. Suddenly, Anya is missing. And Michael, hiding dark secrets behind his mask of perfectionism, is approached by mysterious stalker, Thomas Wolf with evidence of his involvement…
“Overture” is the first episode of PAS DE DEUX, an eight-hour story about honor, identity, and the effect of trauma and mental …
Coupled Machine Learning Models: Combining Observations And Numerical Analysis In A Physics-Regularized Approach, Austin B. Schmidt
Coupled Machine Learning Models: Combining Observations And Numerical Analysis In A Physics-Regularized Approach, Austin B. Schmidt
LSU New Orleans Theses and Dissertations
This dissertation investigates surrogate modeling for fixed-location environmental forecasting using novel data-combination techniques. The work surveys the landscape of observational measurements and numerically generated data, identifying similar research and gaps in current methodologies. The ratio-coupled training framework is introduced to combine two data sources per predicted feature through a tunable parameter that weights training signal strength. An optimization scheme is developed to simultaneously tune surrogate weights and the coupled signal ratio, allowing relative influence between signals to act as an explicit regularizer. Three case studies demonstrate the methodology and approach in a variety of contexts. The first study is based …