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The Prillwitz Mammoth: Taxonomy, Sex, Age, & Delayed Skeletal Maturation Of A Geologically Young Mammoth, Anna Rybachek

Honors Theses

The Prillwitz mammoth, a nearly complete mammoth skeleton found in Southwest Michigan in 1962, is one of the geologically youngest mammoths from North America (AMS C-14 date: 11,300 ± 100 BP). Bones are well preserved; some long bones show post-mortem flaking, scratches, or grooves of unknown origin. All long-bone epiphyses remain unfused except the distal humerus, suggesting it was < 28 years old at death. In contrast, the skull and mandible preserve M3s and m3s, respectively, that are in mid-wear, indicating an Asian Elephant Year dental age of ~45-50 years. Long bone size and inferred shoulder height are consistent with the size of a large woolly mammoth (Mammuthus primigenius) or small to mid-sized Columbian mammoth (Mammuthus columbi), but dental evidence is most consistent with M. columbi.

Pelvic dimensions suggest it is a male. The ≥ 17-year mismatch between age inferred from tooth progression and wear (~45 Asian Elephant Years) and age inferred from epiphyseal fusion (< ~28 Asian EY if male) may indicate either substantially accelerated dental progression or delayed skeletal maturation for this mammoth; we deem the latter more likely. Based on modern analogs, delayed maturation could have been due to severe malnutrition, hormonal imbalance, illness, or genetic factors. Given the geologically young age of the Prillwitz mammoth (likely near the time of mammoth extinction), we speculate that delayed skeletal maturation may have been attributed to environmental stressors near the end of the Pleistocene. Further work is warranted on very late mammoths.

On Farms, Tillage Intensity Shown To Affect Beneficial Insect Communities, Nicholas Gosling

UNH Today Archive

No abstract provided.

Evaluation Of Gfap And Ptau Protein Expression In Male And Female Cci Mouse Models, Sara Wallace

Honors Program: Senior Projects (Public)

Traumatic Brain Injury (TBI) is a serious public health concern that leads to the death or disability of thousands of individuals in the US annually. Progression of TBI involves primary damage from the initial, mechanical injury and secondary damage, from nonmechanical, pathological dysfunction. The secondary damage mechanisms can be better understood, diagnosed, and treated through the quantification of TBI biomarkers. The two biomarkers of interest in this study are pTau and GFAP. The male and female mouse models showed similar significant increase in GFAP following injury, as well as a general lack of increase in pTau expression following the injury. …

Evaluation Of The Effect Of In Ovo Applied Bifidobacteria And Lactic Acid Bacteria On Enteric Colonization By Hatchery-Associated Opportunistic Pathogens And Early Performance In Broiler Chickens, Mitchell C. Rowland, Aaron J. Forga, James Higuita, Makenly E. Coles, Billy M. Hargis, Christine N. Vuong, Danielle Graham

Poultry Science Faculty Publications and Presentations

Probiotics have been used to promote pioneer colonization by beneficial bacteria in poultry. The purpose of the present study (four trials) was to determine if an in ovo injection with Bifidobacterium saeculare (B2-2, B3-4) and/or lactic acid bacteria (LAB18, LAB46) at d18 of embryogenesis reduced Enterococcus and Gram-negative bacterial colonization in the gut at hatch. An environmental challenge model was used to simulate microbial contamination in large-scale hatch cabinets in a laboratory setting. In all trials, gut homogenates obtained from chicks at hatch were plated to enumerate relevant bacterial populations. Performance was evaluated in trials two and four. The top …

À Propos De « Cilama » (Hady Zaccak, 2024), Joseph Korkmaz

Regards

Cilama (2024) est un documentaire du réalisateur libanais spécialiste du genre Hady Zaccak. Le titre est une déformation de « cinéma » par le dialecte populaire de Tripoli, la deuxième grande ville et chef-lieu du nord du Liban. Des années trente et jusqu’à la guerre civile en 1975, Tripoli comptait une trentaine de salles qui attiraient une foule de spectateurs avides de divertissement, d’évasion, de rencontres et de découvertes. Aujourd’hui ces salles ont fermé leurs portes et, contrairement à celles du centre-ville de Beyrouth qui ont été rasées dans le cadre de la reconstruction et de la modernisation, elles sont …

Uterine Pgrmc2 Deficiency Attenuates Endometrial Hyperplasia And Cancer And Prolongs Lifespan In A Pten Loss-Of-Function-Induced Cancer Model, John P Lydon, J Julie Kim, John J Peluso, James K Pru

Faculty, Staff and Students Publications

The expression of members of the progesterone receptor membrane component (PGRMC) family, particularly PGRMC1, is elevated in diverse types of cancers, particularly those of the female reproductive system. While xenograft tumor studies using human transformed cell lines in immunocompromised mice have suggested that PGRMC1 enhances tumor growth and chemoresistance, the exact role of members of the PGRMC family in cancer development in vivo remains unclear. In this study, we examined the effect of deleting Pgrmc2 on the development of endometrial hyperplasia and cancer using a murine phosphatase and tensin homologue (Pten) conditional loss-of-function model. We previously established that …

Histone Acetylation Modulators In Breast Cancer

Faculty, Staff and Students Publications

Breast cancer is the most prevalent cancer in women worldwide. Aberrant epigenetic reprogramming such as dysregulation of histone acetylation has been associated with the development of breast cancer. Histone acetylation modulators have been targeted as potential treatments for breast cancer. This review comprehensively discusses the roles of these modulators and the effects of their inhibitors on breast cancer. In addition, epigenetic reprogramming not only affects breast cancer cells but also the immunosuppressive myeloid cells, which can facilitate breast cancer progression. Therefore, the review also highlights the roles of these immunosuppressive myeloid cells and summarizes how histone acetylation modulators affect their …

Progesterone Receptor In Uterine Glands Is Required For Pregnancy Establishment In Mice, Francesco J Demayo, John P Lydon, Thomas E Spencer, Andrew M Kelleher

Faculty, Staff and Students Publications

Embryo implantation is a critical event in the establishment of pregnancy, and implantation failure is a major cause of pregnancy loss in women. Coordinated, cell-type specific responses to the ovarian steroid hormones, estrogen, and progesterone, within the endometrium underlie successful embryo implantation and pregnancy establishment. In this study, we utilized a glandular epithelium (GE) specific Cre recombinase mouse line that is only active in the adult (Prss29-Cre) to determine the biological role of progesterone receptor (PGR) in uterine glands during pregnancy. Conditional ablation of PGR specifically in the GE compromised fertility due to defects in uterine receptivity and embryo implantation. …

Video Animation: Improving Older Adults Patients Knowledge And Motivation Related To Hypertension Diet, Gusti Ayu Kade Budiarti, Sri Susanty, Ruslan Madjid, Ramadhan Tosepu

Jurnal Keperawatan Indonesia

Hypertension is a dangerous medical condition that can increase the risk of heart, brain, and renal problems, among other issues. A balanced diet is an essential hypertension control intervention. This study seeks to examine the efficiency of employing animation media to explain the application of diets that prevent hypertension and boost the understanding and motivation of senior patients at Bahteramas Regional General Hospital. In both the control and intervention groups, a quantitative-quasi-experimental design was adopted, with pre-test and post-tests. Data was obtained via questionnaires from 92 respondents chosen using a purposive sampling approach, with 46 in the intervention group from …

Spatial Clustering Of Urban Villages On Stunting Babies Data In Samarinda Using The Dbscan Model, Nanda Arista Rizki, Asyril Asyril, Isran K. Hasan, Maulidah Maulidah, Carolina Fadia Dewi, Dhira Syahlafandi

Media Kesehatan Masyarakat Indonesia

The government has set an annual target to reduce stunting rates. To achieve this, the Health Department must implement well-targeted policies based on a prioritized approach, ensuring that interventions are comprehensive and coordinated for maximum effectiveness. This study aimed to cluster urban villages in Samarinda based on stunting data, including the number of cases, baby weight, and height, using the Density-Based Spatial Clustering of Applications with Noise (DBSCAN) model. The optimal model was selected by determining the highest silhouette score from various combinations of epsilon (ε) and MinPts values. The best results were obtained with ε = 0.95 and MinPts …

Geo-Ai For Wetland Classification And Evolutionary Analysis, Lirong Yin

LSU Doctoral Dissertations

Wetlands, as a crucial component of the Earth's ecosystem, play a vital role in maintaining ecological balance and preserving biodiversity. However, wetlands are currently facing severe challenges, as both natural and human-induced factors are contributing to their global degradation. Gaining a deep understanding of the species composition and biodiversity within wetland-covered areas and accurately analyzing their changing trends not only helps assess the current and future state of wetlands but also provides strong support for the formulation of scientifically sound wetland conservation strategies. In recent years, the rapid development of geospatial intelligence and remote sensing technologies has brought new opportunities …

Galectin-1 Inhibition As A Strategy For Malignant Peripheral Nerve Sheath Tumor Treatment, Hsiao-Chi Wang, Keila E Torres, Roger Xia, Marcio H Malogolowkin, Ssu-Wei Hsu, Tsung-Chieh Shih

Faculty, Staff and Student Publications

Neurofibromatosis type 1 (NF1) is an inherited disorder that predisposes individuals to malignant peripheral nerve sheath tumors (MPNSTs), a highly aggressive sarcoma with limited treatment options and poor prognosis. This study explores the potential of targeting the interaction between Galectin-1 and Ras as a novel therapeutic strategy for MPNSTs. Through molecular docking, we identified critical residues involved in the Galectin-1 and H-Ras interaction. We developed LLS30, a compound designed to target this Ras-binding pocket on Galectin-1, and tested its efficacy. LLS30 effectively disrupted the Galectin-1/Ras interaction, causing Ras delocalization from the plasma membrane and inhibiting Ras signaling. In vitro experiments …

Encountering Coasts: The Contested Geographies Of Young People's Coastal Citizenship[S], Mark Holton

School of Geography, Earth and Environmental Sciences

This paper examines the contested geographies of young people's citizenship practices and performances in marine and coastal environments. This is important in developing original knowledge of how encounters with new and different coastal places, practices, people, morals and ethics can affect young people's citizenship practices and performances and how young people relate meaningfully with[in] coastal environments. Using a novel digital scrapbooking technique and qualitative interviews, conducted with 22 young adults aged 18–30 in Plymouth, UK, this paper examines how and why young people's everyday engagements and encounters with coastal environments can shape their understandings of environmental and social care. In …

Rethinking Hope In Dystopian Times: A Critical Assessment, Gerard Delanty

Emancipations: A Journal of Critical Social Analysis

I begin by discussing the salience of the idea of hope for the present day with some examples which illustrate its strong political and cultural resonance. However, the now very extensive literature on hope, mostly in moral and political philosophy, is somewhat diverse and unclear as regards how it should be understood in ways that make it meaningful for the present day. While some of the most important perspectives are in the political philosophy of hope, there is almost no discussion of its sociological significance. I offer a brief critical strand of the main themes in recent writing on hope …

Sanayin Sa Pagbasa: Panlunas Sa Suliranin Sa Pagbabasa Sa Filipino Ng Mga Mag-Aaral Sa Ikawalong Baitang Ng Poblacion National High School Taong Panuruan 2022-2023, Jonathan G. Batara

Annual Research Congress for High School and Elementary Teachers, Researchers, and Scholars (ARCHERS)

Ang pananaliksik na ito ay sumusuporta sa Sustainable Development Goal para sa Quality Education ng United Nations. Isinagawa ito upang matulungan ang mga mag-aaral na may suliranin sa pagbabasa. Ito ay pagtitiyak na pantay na kalidad ng edukasyon ang naibibigay sa lahat ng mag-aaral. Kabilang sa pananaliksik na ito ang labing-apat na mag-aaral mula sa Ikawalong baitang na may mga gulang na 13 hangang 14 taon. Sila ang mga mag-aaral na nahihirapan sa pagbabasa at mabagal sa pagbabasa. Ang memorandum ng kagawaran at batas tulad ng DM No. 173 s.2019 Hamon: Bawat Bata Bumabasa (3Bs Initiative), ECARP o Every Child …

Reading Of A Walkable University Landscape In North Central Nigeria, Salawu Ahmed, Isa Bala Muhammad, Abubakar Danladi Isah

Architecture and Planning Journal (APJ)

Walkable landscapes are tied to people’s perception of their environment. Walking also constitutes the most equitable means of transport because it is available to all. Studies have shown that walking has inherent benefits to the environment as well as the health benefits to the partaker. Most University campuses are characterized by large landscapes within which movements are made to connect facilities located far apart from each other. It is therefore important to understand the constituents of what makes a university campus walkable. This study therefore examined the character of a walkable campus landscape through the lens of qualitative research paradigm. …

A Nonlinear Cross Diffusion Model Analysis By Using Holling Type Iii Functional Response To Describe Fish And Zooplankton Dynamics Taking Into Account The Fishing Effect In The Ecosystem, University Of Nazi Boni, Bobo Dioulasso, Burkina Faso, W. Ouedraogo, H. Ouedraogo

Baku Mathematical Journal

In this paper, we analyse a mathematical model of a cross-diffusion and selfdiffusion system describing the dynamics of fish and zooplankton population. A type III Holling functional response was used in the formulation of the model taking into account the effect of fishing in the ecosystem. Satisfactory results concerning the local and global existence properties of the solutions. Persistence conditions as well as the local stability of equilibrium states are established. We have shown in particular that, under certain conditions, cross-diffusion can trigger the emergence of spatial patterns. Numerical experiments are performed to visualize complex spatial patterns and dynamic behaviour …

Is Microbial Production A Good Option For Exceptionally Low Cost Monoclonal Antibodies For Global Access?, Vijay Yabannavar

Microbial Engineering III (MEIII)

Please click Additional Files below to see the full abstract

Epigenetic Regulation And Tumor Suppressive Function Of Lncrna Ep300-As1 In Nasopharyngeal Carcinoma Through Activation Of Tfap2c Binding To Cst6: Implications For Diagnosis, Prognosis, And Therapy, Chengliang Xing, Shun Ding, Tingting Duan, Zhiqun Li, Jinren Yan, Yu Kuang, Qibing Liu, Zhonglin Mu

Integrated Health Sciences Faculty Research

The long non-coding RNA EP300-AS1 (lncRNA EP300-AS1), identified as a potential regulatory factor in various cancers, remains underexplored in nasopharyngeal carcinoma (NPC). This study investigated EP300-AS1’s regulatory mechanisms in NPC, particularly its interaction with transcription factor AP-2 Gamma (TFAP2C) and its effect on cystatin E/M (CST6) expression. Employing clinical samples and NPC cell lines, we conducted in vitro and in vivo xenograft experiments to assess the impacts of modulating EP300-AS1 expression. Techniques such as CCK8, migration, scratch, apoptosis assays, cell cycle analysis, immunoblotting, and fluorescence experiments elucidated EP300-AS1’s role in NPC. The interaction between EP300-AS1 and TFAP2C in regulating CST6 …

Enforcement Activities And Profiling Techniques Of Wildlife Rangers In Nigeria's Lowland Forest Reserves: A Mixed-Methods Study On Wildlife Law Transgressions, Norris I. Erhabor, Gloria Aimien Erhabor

Journal of Bioresource Management

This mixed-methods study investigates the enforcement activities and profiling techniques employed by wildlife rangers in Nigeria's lowland forest reserves to address wildlife law transgressions. The research integrates enforcement strategies, socio-economic factors, community involvement, and governance structures to evaluate the effectiveness of ranger activities. Data collection was conducted in the Omo Biosphere Reserve, Gele Gele Forest Reserve, and Okomu National Park, utilizing both primary and secondary sources, including interviews with 24 wildlife rangers. Key findings reveal that unauthorized entry, possession of specific tools, and suspicious behaviors are primary indicators used by rangers to identify potential law violators. Poaching activities predominantly occur …

The Effect Of Reciprocal Teaching Learning Model Assisted By Flipbook On Critical Thinking Ability, Reza Nurropidah, Mohd Hazwan Mohd Puad

Jurnal Pendidikan Sains

This study aims to determine the effect of the reciprocal teaching learning model assisted by Flipbook on students' critical thinking skills. The research method used was quasi-experimental. We conducted research on two classes: the experimental class and the control class. We conducted our research activities at Elementary School Biyawak in Majalengka Regency. The total population studied was 58 students, divided into two groups: the experimental class totaling 30 people and the control class totaling 28 people, with the sampling technique used being non-probability sampling with a purposive sampling approach. We collected the research data using a pretest and posttest with …

Dna Methylation In Periodontal Disease: A Focus On Folate, Folic Acid, Mitochondria, And Dietary Intervention, Elzbieta Pawlowska, Joanna Szczepanska, Marcin Derwich, Piotr Sobczuk, Nejat Düzgüneş, Janusz Blasiak

Pacific Faculty Work

Although periodontal disease (PD) is reported to be associated with changes in various genes and proteins in both invading bacteria and the host, its molecular mechanism of pathogenesis remains unclear. Changes in immune and inflammatory genes play a significant role in PD pathogenesis. Some reports relate alterations in cellular epigenetic patterns to PD characteristics, while several high-throughput analyses indicate thousands of differentially methylated genes in both PD patients and controls. Furthermore, changes in DNA methylation patterns in inflammation-related genes have been linked to the efficacy of periodontal therapy, as demonstrated by findings related to the cytochrome C oxidase II gene. …

Impact Of Climate Change On The Diversity And Abundance Of Wintering Birds At A Northern African Wetland - Case Study Of Oglat Eddaira Wetland (Naama, Western Algeria), Ahmed Toufik Youcefi, Gouacem Ali, Litim Kouider, Haddi Leila, Messaoui Fatima

Journal of Bioresource Management

The Mediterranean regions have been classified as the areas of the world most susceptible to the effects of environmental change. These regions are sensitive to drought and rising temperatures and with heightened aridity in the next several years. The purpose of this paper is to study the effects of climate change on the diversity and abundance of wintering birds in the Oglat Eddaira wetland located in western Algeria and classified in the Ramsar list. This study is based on the comparison between some indices of biodiversity: species richness, abundance, Shannon-Weiner and Simpson Index, during the period 2015 to 2024 and …

Aerial Phytomass And Carbon Sequestrated By The Kitshanga Forest Massif In The Wamba Valley In Dr-Congo, Mayanu Pemba, Ntalakwa Makolo, Kidikwadi Tango, Lubini Ayingweu

Journal of Bioresource Management

Aerial phytomass and carbon sequestrated by the Kitshanga forest massif in the Wamba valley in DR-Congo. The general objective was to evaluate the aerial phytomass and the carbon contained in the ligneous tissues of the trees. Specifically, the research aims to: (i) inventory all individuals in the Kitshanga gallery forest; (ii) identify the species in the study area; (iii) determine the floristic composition and density of the stand studied and (iv) evaluate the phytomass and the carbon sequestered by this vegetation. Inventory devices full on 1 hectare subdivided by 400 m² to obtain 25 plots which constitute the size of …

Video Discharge Instructions Increase Patient Understanding For Office-Based Procedures: A Randomized Controlled Study, Mohit Khera

Faculty, Staff and Students Publications

Background: Health literacy significantly influences healthcare outcomes, with poor literacy leading to worse quality of life, increased mortality, and higher readmission rates. Recent efforts to improve post-encounter education include structured teach-back methods, patient preference assessments, and standardized discharge instructions. Studies in emergency departments have shown that incorporating video discharge instructions enhances patient understanding and retention of care information. To address the gap in urology, this study aims to evaluate patient comprehension and satisfaction with video discharge instructions following clinic-based vasectomy procedures.

Methods: We performed an Institutional Review Board approved (#H-51614) unblinded randomized controlled study with written consent from each participant. …

Avifauna Of Kheri Morat National Park: Role Of Agricultural Habitat In Maintaining The Diversity Of Birds In The Presence Of Threats In Adjacent Forest Habitat, Syed Ali Hasnain Mosvi, Saeed Azam, Abdullah Ibrahim, Saleha Abbasi, Nadeem Munawar, Muhammad Arslan Asadi

Journal of Bioresource Management

Increasing land use for agricultural practices is commonly perceived as a threat to the avian diversity. However, a number of avian species depend on these croplands for food, water, and shelter. The present study was conducted in Khairi National Park, Pakistan, for the discourse of awareness gaps about the avifaunal diversity of the protected area and to compare the bird’s diversity in the agriculture fields and native forests. For the current study, the habitat was divided into two habitat categories, i.e., forest and croplands. The sampling was executed between February 2014 and February 2017. Stratified random sampling was used to …

Study On Predisposing Factors And Control Measures Against Cryptosporidiosis In Buffalo Calves At Cattle Colony Hyderabad, Sindh, Pakistan, Ali Ul Murtaza, Abdul Latif Bhutto, Jam Kashif Zaman, Mansoor Tariq, Amjad Hussain Mirani, Riaz Ahmed Laghari, Pervez Ahmed Khoso, Muhammad Mohsen Rahimoon, Abdul Saboor, Fayaz Hussain

Journal of Bioresource Management

The current study looked at the variables affecting the frequency of Cryptosporidium Parvum in buffalo calves at the Hyderabad Cattle Colony. From calves, 100 fecal samples were taken in total, preserved, and analyzed using direct smear and Ziehl-Neelsen staining methods. 74 percent of the samples tested positive for Cryptosporidium Parvum. Disease rates were higher in Nili Ravi calves (86 %) compared to Kundhi calves (62 %), with a statistically significant difference (p

Empathetic Teaching: Why Authentic Blind Representation In Curricula Matters, Olivia Thomakos

Oral Presentations

Understanding the lived experience of blindness is challenging for sighted individuals. While literature can provide insights into this experience, many portrayals are written by sighted authors who rely on metaphor or their own fears of blindness. For blind authors, the challenge of connecting with sighted readers is compounded by the fact that reading itself is performed differently by sighted and non-sighted individuals. This essay explores how authentic authorship can foster empathy and understanding of blindness, and how introducing students to literature with genuine blind representation in school curricula can positively influence perceptions of blindness. Mark Paterson's article "Blindness, empathy, and …