Digital Commons Network^™

Participatory Longitudinal Qualitative Interview Study To Understand Autistic Gynaecological And Obstetric Health: The Autism From Menstruation To Menopause Study Protocol, Amy Brown, Kathryn Williams, Aimee Grant, Gemma L. Williams, Harriet Axbey, Abigail Wilkins, Ellen Firth, Hazel Lim, Helen Cave, Christina Nicolaidis, Multiple Additional Authors

School of Social Work Faculty Publications and Presentations

Autism is a lifelong minority neurotype present from birth. There is a dearth of credible evidence to suggest gender variation in Autism prevalence, despite historical under-diagnosis of women. Autistic people Assigned Female At Birth (AFAB) have worse physical and mental health compared with non-Autistic peers. To date, the reproductive health experiences of Autistic AFAB people have been under-investigated.Methods and analysis This study aims to co-develop a quality improvement intervention to improve the reproductive health of Autistic people. The study uses Community Partnered Participatory Research (an approach similar to Community-Based Participatory Research), largely through a Community Council that co-governs the study. …

Multimodal Assessment Battery And Heart Rate Variability Enhance Clinical Utility Of Buffalo Concussion Treadmill Test, Daniel Miner, Michael Shiraishi, Pamela Gibbons, Rahul Soangra, Brent Harper

Physical Therapy Faculty Articles and Research

Context: The Buffalo Concussion Treadmill Test (BCTT) for exercise intolerance following concussion may highlight underlying autonomic dysfunction. Autonomic function at rest and with exertion may be predictive of neurocognitive performance for individuals with sports-related concussion. The purpose of this study is to explore the feasibility and utility of combining multimodal assessments with heart rate variability (HRV) measures during the BCTT for individuals with a remote history of concussion. Design: Prospective cohort study design, pretest/posttest. Methods: Participants included 5 males and 5 females (N = 10, age: 25.2 [3.3] y old, height: 173.2 [11.2] cm, mass: 73.4 [13.7] …

Guidelines For Returning To Dance Following Concussion: Adaptations From Sport Concussion Literature, Sheyi Ojofeitimi, Lauren Mcintyre, Elizabeth Barchi, Sarah S. Rae, Brittney Winnitoy, Jeffrey A. Russell

Department of Family & Community Medicine Faculty Papers

Sport concussion receives substantial attention as a public health concern. Conversely, performing artists, including dancers, sustain concussions, but these aesthetic athletes do not receive the same level of consideration nor care for this injury as that offered to traditional athletes. The concussion literature pertaining to dance is sparse, and, to our knowledge, no recommendations exist for the crucial aspect of care related to returning to dance following a concussion. The purpose of this article is to assimilate the current knowledge about post-concussion return to activity management in sport—the closest analog of the physical demands required in dance—as a means to …

Staff Education To Improve Depression Management Using Mindfulness Meditation Intervention, Ndubuisi Chimezie Obioha

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education to Improve Depression Management Using Mindfulness Meditation Intervention by Ndubuisi Obioha MSN, Walden University, 2021 BSN, Grand Canyon University, 2017 Executive Summary Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University November 2024 Summary The problem of poor depression management guided this quality improvement staff educational project due to treatment nonadherence issues. The providers at the project site had minimal knowledge of self-help interventions that can be used to assist individuals with depression who often face treatment barriers. Failing to address the problem could result …

Strategies Business Owners Use To Comply With Federal State And Local Taxes, Olohigbe O. Abaya

Walden Dissertations and Doctoral Studies

Tax regulations are constantly changing, increasing complexity for business owners to meet federal, state, and local obligations. Non-compliance can lead to severe consequences, including fines, legal action, and damage to a company’s reputation. Grounded in the planned behavior theory, the purpose of this qualitative pragmatic inquiry was to identify and explore practical steps small business owners take to comply with federal, state, and local tax requirements. Participants were seven business leaders in the United States. Data were collected through semistructured interviews, as well as a review of public websites and documents. Through thematic analysis, three themes were identified: professional assistance, …

Attachment-Based Intervention For Inattention, Hyperactivity, And Impulsivity: Does Relationship Matter?, Stephanie M. Ess

Walden Dissertations and Doctoral Studies

While the prevailing notion attributes attention deficit hyperactivity disorder (ADHD) largely to a genetic response, there is increasing evidence of its multifactorial nature, involving both genetic and environmental factors, including the parent–child attachment relationship. Given the limitations of pharmacological and behavioral treatment methods, this study addressed the critical need for alternative ADHD interventions. The purpose of this study was to examine the differences in inattention, hyperactivity, and impulsivity among toddlers approximately 48 months old in an attachment-based intervention group (n = 63), a control intervention group (n = 58), and a low-risk group not requiring intervention (n = 52). Grounded …

Effective Transformational Leadership Strategies For Catalyzing Employee Morale For Innovation Within Fashion Boutiques, Jasmine Shanise Glover

Walden Dissertations and Doctoral Studies

Business owners risk failure when they lack effective strategies for innovation and employee morale. In the fashion industry, many leaders have been forced to close their brick-and-mortar stores due to inadequate innovation and leadership strategies, which hindered their ability to adapt and thrive. The purpose of this qualitative pragmatic inquiry study was to explore and identify the strategies that fashion industry leaders use to improve employee morale, foster innovation, and drive business success. The participants consisted of seven fashion boutique leaders from the United States, each of whom managed either an active online boutique or a brick-and-mortar store. Data were …

Small- And Medium-Sized Enterprises Strategies For Sustainability And Profitability Beyond 5 Years, Bawi Ming

Walden Dissertations and Doctoral Studies

Up to 80% of small- and medium-sized enterprises (SMEs) fail within the first 5 years due to factors like financial mismanagement, market challenges, and insufficient long-term planning. To prevent these failures, organizational leaders must adopt effective sustainability strategies, as SME closures lead to job losses, economic instability, and lost innovation opportunities. Grounded in the resource-based view and general systems theories, the purpose of this qualitative pragmatic inquiry project was to explore successful strategies that SME leaders in Maryland used to sustain their businesses beyond their initial 5 years. Data were collected from six SME leaders using semistructured interviews and reviews …

Corporate Social Responsibility Strategies For Retaining Skilled Talent To Enhance Competitive Advantage, Linwood Corneilus Cottner Jr.

Walden Dissertations and Doctoral Studies

Aviation business leaders often lack effective corporate social responsibility (CSR) strategies to retain highly skilled employees, a crucial factor in gaining a competitive advantage. To maintain this advantage, aviation leaders must consistently recognize employee retention as a critical challenge and a key element in sustaining long-term success. Grounded in Herzberg’s two-factor theory, the purpose of this qualitative multiple-case study was to explore the corporate social responsibility strategies aviation business leaders use to retain highly skilled employees to enhance their competitive advantage. The participants were three aviation business leaders from the Midwest United States who successfully implemented corporate social responsibility strategies …

Staff Education Project Strategies For Reducing No-Shows, Ekop Graham

Walden Dissertations and Doctoral Studies

The staff education project addressed a gap in managing patient no-shows at a psychiatric clinic, where approximately 25% of scheduled appointments were missed. This issue severely impacted patient care continuity, delayed necessary treatments, and increased healthcare costs. The clinic’s practices of using reminder calls and emails had been insufficient in reducing no-shows. A literature review highlighted several effective interventions in imprvoing patient adherence and reducing missed appointments, such as facilitated appointment scheduling, personalized communication, and patient-centered strategies. The project aimed to enhance the nursing staff’s knowledge in addressing patient no-shows by educating them on causes, including logistical barriers and psychological …

Corynebacterium Minutissimum As A Rare Cause Of Tibial Osteomyelitis: A Case Report And Literature Review, Ayub Ansari, Dania Shoaib, Maher Asfour, Xiyue Wang, Pooja Sharma

Student Publications

Osteomyelitis is commonly caused by pathogens like Staphylococcus aureus, but rare organisms such as Corynebacterium minutissimum, typically associated with superficial skin infections, can also be implicated. Recognizing these atypical pathogens presents diagnostic and therapeutic challenges, especially in the presence of orthopedic hardware. We conducted a literature review yielding 25 studies and encompassing 797 patient cases, which highlights the emerging role of Corynebacterium species in osteomyelitis, particularly following trauma or surgical interventions. A 72-year-old man with a history of chronic right tibia and fibula fractures from a motor vehicle accident presented with progressively worsening leg pain over six months. …

Decoding Ras Mutations In Thyroid Cancer: A Meta-Analysis Unveils Specific Links To Distant Metastasis And Increased Mortality, Isabel Riccio, Alexandra Laforteza, Madeleine B. Landau, Mohammad H. Hussein, Joshua Linhuber, Jonathan Staav, Peter P. Issa, Eman A. Toraih, Emad Kandil

School of Medicine Faculty Publications

Background/objectives: RAS mutations are common in thyroid cancer, but their impact on clinical outcomes remains controversial. This study aimed to evaluate the prevalence of RAS mutations in thyroid cancer and their association with various clinical and pathological features. Methods: We conducted a systematic review and meta-analysis of studies reporting on RAS mutations in thyroid cancer. Both one-arm and pairwise meta-analyses were performed to compare outcomes between RAS-mutated (RAS+) and wild-type (RAS-) thyroid cancers. Results: Our analysis included 2552 thyroid cancer patients from 17 studies. The overall prevalence of RAS mutations was 35.4 % (95 % CI: 22.7 %–50.7 %). NRAS …

Maresin-Like 1 Ameliorates Neuropathology Of Alzheimer's Disease In Brains Of A Transgenic Mouse Model, Pallavi Shrivastava, Yan Lu, Shanchun Su, Yuichi Kobayashi, Yuhai Zhao, Nathan Lien, Abdul-Razak Masoud, Walter J. Lukiw, Song Hong

School of Medicine Faculty Publications

(1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer's disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology. This can potentially be achieved by the treatment with specialized pro-resolving lipid mediators (SPMs), which should resolve neuroinflammation in brains. (2) Methods: Here, we report the histological effects of long-term treatment with an SPM, maresin-like 1 (MarL1), on AD pathogenesis in a transgenic 5xFAD mouse model. (3) Results: MarL1 treatment reduced Aβ overload, curbed the loss of neurons in brains especially cholinergic neurons associated with cleaved-caspase-3-associated apoptotic degeneration, reduced microgliosis and the pro-inflammatory M1 …

Human Papillomavirus Vaccination Coverage In Genesee County: Geographic Disparities And The Need For Community-Partnered Vaccination Efforts, Olivia G. Aspiras, Joanne Herman, Todd Lucas, Eric Adjei Boakye, Ariel Washington, Hayley S. Thompson

Michigan Journal of Public Health

There are approximately 37,000 new cases of cancer attributed to human papillomavirus (HPV) each year in the United States. The HPV vaccine is generally widely available, low cost, and highly effective in providing long-lasting protection against HPV. Yet, HPV vaccination rates remain suboptimal among children and adolescents in the United States. The present commentary spotlights HPV vaccination within Genesee County. Using data from the Michigan Department of Health and Human Services, we describe the alarmingly low HPV vaccination rates in Genesee County relative to state and national vaccination rates. We then identify potential barriers to vaccination and offer evidence-based strategies …

The Revised Cdc Chronic Pain Guidelines And Payer Opioid Analgesic Policies In Michigan, Victoria Tutag Lehr, Cynthia L. Arfken

Michigan Journal of Public Health

Abstract

The 2016 publication of A Guideline for Prescribing Opioids for Chronic Pain by the Centers for Disease Control and Prevention motivated commercial and Medicaid payers to restrict their opioid prescribing policies including the imposition of hard limits on opioid daily dosages and duration. One result of these policies was an increase in abrupt opioid discontinuation and rapid tapering events for patients receiving long-term opioid therapy. Responding to this misapplication of the 2016 guideline, the 2022 revised guidelines emphasized individualized opioid therapy and exclusion of certain chronic diseases. However, it is not known if the payers changed their policies to …

Artificial Christmas Trees More Popular Than Real Trees In Maine; Majority Expect White Christmas 12/17/2024, Unh Survey Center

All UNH Survey Center Polls

Maine residents prefer having artificial Christmas trees rather than real trees, while more than a quarter of Mainers say they will not have a tree at all this year. Two-thirds of Mainers prefer to say "Merry Christmas" rather than "Happy Holidays". Just over half of Mainers expect a white Christmas where they live, particularly those living in Central Maine.

No Snow, Fake Trees In The Granite State For Christmas 12/17/2024, Unh Survey Center

All UNH Survey Center Polls

Mild weather in the Granite State is dampening expectations for a white Christmas and more people will have artificial than real Christmas trees. Granite Staters increasingly prefer to say "Merry Christmas" rather than "Happy Holidays", though many say it does not matter to them which term businesses use.

Pathways From Socioeconomic Factors To Major Cardiovascular Events Among Postmenopausal Veteran And Nonveteran Women: Findings From The Women's Health Initiative, Hind A Beydoun, May A Beydoun, Rebecca L Kinney, Simin Liu, Rona Yu, Matthew Allison, Robert B Wallace, Qian Xiao, Longjian Liu, Philippe Gradidge, Su Yon Jung, Hilary A Tindle, Shawna Follis, Robert Brunner, Jack Tsai

Faculty, Staff and Student Publications

BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of death for women in the United States, with veterans being at potentially higher risk than their nonveteran counterparts due to accelerated aging and distinct biopsychosocial mechanisms. We examined pathways between selected indicators of socioeconomic status (SES) such as education, occupation, household income, and neighborhood SES and major CVD events through lifestyle and health characteristics among veteran and nonveteran postmenopausal women.

METHODS AND RESULTS: A total of 121 286 study-eligible WHI (Women's Health Initiative) participants (3091 veterans and 118 195 nonveterans) were prospectively followed for an average of 17 years, during which …

Acts Of Tyranny And Terror: Violence, Propaganda, And The Southern Tenant Farmers Union In 1930s Arkansas, Charles Bonet

Theses and Dissertations

The objective of this thesis project is to tell a compelling story of the violence that occurred during the early years of the Southern Tenant Farmers Union in 1930s Arkansas. The story will be told through a close examination of experiences of significant STFU figures, as well as through an examination of some key events. Special attention will be paid to the various forms of violence and intimidation that proliferated and, additionally, the ways in which propaganda often factored in. A podcast series will be the media utilized to tell this story. The podcast format allows for the project to …

Traveling Waves In Biological Population Models, Ahlam Alzahrani

Theses and Dissertations

In this thesis, we examine the existence of traveling waves in population models. We begin by exploring conditions under which traveling waves exist, even when the migration probability lacks a density function or, if the density function exists, it may be discontinuous. To address this, we impose certain conditions that ensure the monotonicity of the evolution operator, enabling the application of the Monotone Iteration Method. Next, we explore the existence of monotone traveling waves in a general class of integral-difference population models that depend on both the previous state and long-term memory, allowing for the consideration of multiple past states. …

Integrative Single-Cell Genomics And Machine Learning Methods For Tumor Microenvironment Characterization And Survival Prediction, Wenjuan Zhang

Theses and Dissertations

The tumor microenvironment (TME) comprises diverse cell types and plays crucial roles in cancer development and therapeutic response. Single-cell RNA sequencing (scRNA-seq) data quantifies gene expression at the single-cell level, enabling the dissection of heterogeneous cell populations in various biological contexts and diseases. In this work, we developed integrative single-cell genomics and machine learning approaches to characterize the TME and enhance patient survival prediction. We introduced a convolutional neural network (CNN)-based method, cnnImpute, to address the high proportion of missing data in scRNA-seq datasets. cnnImpute effectively imputes missing values while preserving the integrity of cell clusters, achieving superior performance in …

Selective Indel Marker Identification Across The Peanut (Arachis Hypogaea L.) Genome Using Ddradseq, Moin Qureshi, Bi̇rgül Guden, Hi̇lal Şule Tosun, Mojtaba Kordrostami, Sunil Shiwaji Gangurde, Bülent Uzun, Engi̇n Yol

Turkish Journal of Botany

The advent of next-generation sequencing technologies, mainly double digest restriction site-associated DNA sequencing (ddRADSeq), has significantly advanced the development of molecular markers for crop genetics. This study used ddRADSeq to identify and develop insertion-deletion (InDel) markers in 25 peanut genotypes from diverse geographic regions. The bioinformatic analysis unveiled 62728 InDels across the peanut genome, predominantly between 1-5 bp, which constituted 96% of the total, while InDels of ≥ 6 bp accounted for 3.96%. We focused on 1013 InDels of at least 10 bp for further analysis, representing 1.61% of the total reads, with a distribution of 832 insertions and 181 …

Gene-Environment Interactions In Non-Alcoholic Fatty Liver Disease: Insights From Mexican American Populations, Eron G. Manusov, Vincent P. Diego, Marcio Almeida, Jacob Galan, Auwal A. Bala, Marco Arriaga, Natasha Garcia-Rodriguez, Renee Hernandez, Satish Kumar, John Blangero, Sarah Williams-Blangero

School of Medicine Publications

Nonalcoholic Fatty Liver Disease (NAFLD) is a prevalent and complex condition influenced by both genetic and environmental factors. This chapter explores the genotype-by-environment interactions that contribute to the development and progression of NAFLD in the Mexican American population. Using advanced genetic epidemiology and bioinformatics approaches, we investigated how specific genetic variants interact with environmental factors such as depression, acculturation stress, and social determinants of health, to influence NAFLD risk and severity. Our findings reveal significant genotype-by-environment interactions for key NAFLD-related traits, including HbA1c, AST/ALT ratio, and steatosis-controlled attenuation parameter (CAP). We also discuss the application of cutting-edge proteomic and transcriptomic …

Development Of A Health Education Intervention And Its Effectiveness In Improving Mmr Vaccination Confidence, Attitude And Uptake Among Parents Attending Public Health Clinics In Kuala Lumpur, Aida Mohd Azlan

Student Works (2020-2029)

Despite the progress made in Malaysia's vaccination programmes, measles continues to persist. Parental confidence in measles vaccines plays a pivotal role in ensuring successful immunisation. However, there is currently limited research on effective interventions to measure outcomes related to parental trust in MMR (measles, mumps, rubella) vaccination programmes in Malaysia. Hence, this study aims to determine the effectiveness of Health Education Intervention in improving MMR vaccination confidence, attitude, and uptake among parents attending Public Health Clinics in Kuala Lumpur. Methods: This multi-phase quantitative study, conducted from June 2022–March 2024, utilised the Health Belief Model to assess parental vaccine confidence and …

Examining Change In Burnout And Empathy Among Physician Assistant Students During The Clinical And Didactic Years, Jannelle Reynolds, Kimberly Gomes, Nicole M. Sleddens, Jana L. Wardian Phd

Innovations in Health Sciences Education Journal

Few studies investigate how burnout affects physician assistant's student empathy. This study aimed to determine the degree of burnout and empathy in didactic PA students as compared to burnout and empathy in their clinical year.

Methods: One cohort of PA students at a Midwestern university were surveyed twice during their education. Once during didactic and once during the clinical year. Two surveys were used to assess burnout and empathy.

Results: Our findings showed moderate to high levels of emotional exhaustion and depersonalization at the end of the didactic phase and significant improvement in lack of personal achievement and emotional exhaustion …

Front Matter, Michigan Law Review

Michigan Law Review

Front Matter for Volume 123, Issue 1 of Michigan Law Review

Probate Standing, David Horton

Michigan Law Review

Few topics in civil justice have sparked as much criticism as the standing doctrine. The U.S. Constitution and some of its state counterparts require plaintiffs to allege that they suffered an “injury-in-fact” that the defendant caused and that a court can redress. A veritable ocean of commentary argues that this requirement [is confusing, ahistorical, and unmoored from its objectives.

Yet a different manifestation of the standing doctrine has long lurked in obscurity. Standing issues are also common in state probate courts, where the transmission of assets from the dead to the living can affect a variety of parties. But in …

Old, Not Odd: Running Laches Against The States And The Future Of Antitrust After New York V. Meta Platforms, Frank Schulze

Michigan Law Review

In New York v. Meta Platforms, Inc., the United States Court of Appeals for the D.C. Circuit applied equitable laches to an antitrust lawsuit brought by forty-six state attorneys general, holding that they had not brought their claims in their role as law enforcers. Meta Platforms is the latest in a line of cases that has characterized antitrust actions by state attorneys general as non-public and non-governmental. But this characterization is in tension with the historical role of state attorneys general in enforcing the antitrust laws and undermines the original design of the federal antitrust statutes as supplements to …

Influence Of Demographics, Health, And Self-Objectification On Body Acceptance And Body Appreciation In Older Adults, Heather Russell

Walden Dissertations and Doctoral Studies

Prior research has examined the demographic, health, and activity factors influencing how young people, particularly young women, see themselves concerning body appreciation and acceptance. However, body appreciation and acceptance as perceived by older men and women have not been well-studied. The purpose of the study was to examine the extent to which gender, age, quality of life assessment of physical and mental health, physical activity, and self-objectification influence body acceptance by others and body appreciation in adults ages 55-75. Self-objectification theory (SOT) was the framework used to examine the influence of two aspects of self-objectification (lack of autonomy and invisibility) …

Staff Education To Improve Depression Management Using Mindfulness Meditation Intervention, Ndubuisi Chimezie Obioha

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education to Improve Depression Management Using Mindfulness Meditation Intervention by Ndubuisi Obioha MSN, Walden University, 2021 BSN, Grand Canyon University, 2017 Executive Summary Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University November 2024 Summary The problem of poor depression management guided this quality improvement staff educational project due to treatment nonadherence issues. The providers at the project site had minimal knowledge of self-help interventions that can be used to assist individuals with depression who often face treatment barriers. Failing to address the problem could result …