Digital Commons Network^™

Antagomir Treatment For Deep-Space Simulated Changes In The Liver Of Mice, Natalie P. Hayslip

Honors Undergraduate Theses

With the start of NASA’s Artemis program, astronauts will soon leave the protection of Earth’s magnetosphere. Previous studies have established a theme of liver dysregulation associated with the harmful radiation and microgravity experienced in deep space. MicroRNAs (miRNAs) are key regulators of many of the pathologies observed during and after spaceflight, including hepatic fibrosis, making them strong potential biomarkers and therapeutic targets. Therefore, in the present study we investigated the effects of simulated microgravity, galactic cosmic radiation (GCR), and solar particle events (SPE) on miRNAs and mRNAs involved in the TGF-β signaling pathway, a key regulator of fibrosis, senescence, and …

Out Of Sight, Out Of Mind: An Anthropological Exploration Of Overdose Prevention Experiences And Perceptions Among People Who Use Drugs In Orlando, Florida, Maria De Los Angeles Ocando Monaco

Honors Undergraduate Theses

The ongoing overdose problem in the United States, particularly exacerbated by the widespread use of fentanyl, and polydrug use, represents a critical public health challenge. This thesis explores how people who use drugs (PWUD) in Orlando, Florida, are responding to the overdose problem in their community. Drawing on ethnographic research conducted at a syringe services program in Summer 2023, I argue that PWUD in Orlando actively take measures to prevent overdose and overdose deaths but are faced with many obstacles that challenge their overdose prevention efforts. I examine overdose narratives of PWUD to show how factors preventing effective overdose prevention …

The Impact Of Homelessness On Identity In Lgbtq+ Youth Of Color, Isabeau Tyndall Ms.

Honors Undergraduate Theses

This study explores the impact of homelessness on the identity formation of LGBTQ+ youth of color. This group of people is overrepresented within the unhoused community, and unfortunately, under-studied, especially within the qualitative data sector. A literature review found primary themes of identity formation, intersectionality, and discrimination and stigma. In addition to exploring the impact of housing instability on the identity formation of LGBTQ+ youth of color, this study emphasizes the significance of intersectionality in understanding their experiences. By noting the overlap of multiple marginalized identities such as race, sexual orientation, and gender identity, this research illuminates the unique challenges …

On The Rocks: The Association Between Dating And Alcohol Consumption Among Young Adults, Hannah Ettele

Honors Undergraduate Theses

Alcohol consumption is becoming an increasing concern among young adults. In 2018, approximately one-third of young adults in the United States reported binge drinking within the past month (Patrick et al., 2020). This peak in binge drinking during young adulthood raises concerns about physical and mental health. There are also societal implications of alcohol consumption, such as drunk driving, that are particularly evident among this age group (Stewart, 2023). As proposed by the Social Learning Theory (SLT) of alcohol use, there are many factors that motivate young adults to drink (Britton, 2004). Some engage in alcohol consumption to cope with …

Exploring The Relationship Between Trust Learning And Social Media Privacy, Alyssa R. Hayes

Honors Undergraduate Theses

With the rise of social media, many social media users have concerns about their privacy and what they share online. Users must reveal certain pieces of information about themselves to benefit from the convenience of social media and the internet, such as allowing a website to access a specific location to find stores nearby. The problem arises when this data, particularly personal data, is misused. This dilemma of choosing which information to share is incredibly important as social media and the internet evolve. Taking control of one’s privacy may assist in determining which information to share and may reduce stress …

The Effects Of Resistance Training On Older Adults: Increasing Healthspan And Lowering Disability Rates, Michael M. Samuel

Honors Undergraduate Theses

This study analyzed the research on older adults and resistance training exercise and assessed effects on health span and lowering disability rates. A targeted search of the literature was employed using the following key words: sarcopenia, resistance training, hypertrophy, quality of life, disability, activities of daily living, strength training, falls, and functional strength. These were used to find articles that were relevant to the research. Articles were excluded if they focused on young athletes as they did not meet my research age group. Articles that focused on nutrition were also excluded as they pulled the focus away from the impact …

Determining The Differences Of Racial Microaggressions Faced By Multiracial Versus Monoracial Minority Patients Within Healthcare Settings, Elizabeth S. Ommi

Honors Undergraduate Theses

This study examines the disadvantages that multiracial patients face when seeking healthcare in the United States in comparison to the disadvantages encountered by monoracial minority patients. Specifically, this study mainly focuses on the impacts of racial microaggressions within such medical settings. This was explored using a critical discourse analysis, analyzing discourse presented from past research published from 2014 to 2023. Discourse was collected based on its relevancy to the given topic and was analyzed to identify general disadvantages presented for each subpopulation. It was found that multiracial patients face different disadvantages when receiving medical care in comparison to monoracial minority …

The Effect Of Video Game Participation On Ophthalmoscopy Simulation Performance, Abdullah M. Rashid

Honors Undergraduate Theses

This study investigates how video gaming experience influences performance in simulation tasks on an ophthalmoscope simulator among premedical and medical students. Participants were categorized based on their gaming habits, and completion times for simulation tasks were recorded. Results indicate that individuals with greater gaming experience, both casual and hardcore gamers, demonstrated quicker and more accurate performance compared to non-gamers across all skill levels assessed. However, no significant difference was found between casual and hardcore gamers. These findings suggest that moderate engagement in video gaming may enhance visuospatial skills and hand-eye coordination relevant to simulation-based training, with potential implications for medical …

Investigating The Relationship Between Loneliness And Stress In College Students, Daniel A. Serpas-Medina

Honors Undergraduate Theses

Loneliness in college students has been identified as a contributing factor to worsened mental health leading to greater rates of symptoms of depression, anxiety, stress, and others. The COVID-19 pandemic increased the severity of loneliness due to social isolation, however the relationship between loneliness and stress may have changed now in a post-COVID-19 world. This study hypothesized that loneliness does contribute to greater rates of stress in college students and that demographic factors such as gender, race/ethnicity, and first-generation student status influence that interaction. A survey was conducted at the University of Central Florida and acquired 47 total complete responses. …

Postpartum Depression Among Latina Women: A Literature Review, Juan M. Martinez Jr.

Honors Undergraduate Theses

The Hispanic population in the United States has increased to 62.1 million, significantly shaping the country's demographic landscape, with Hispanic women exhibiting the highest fertility rates. Concurrent with the population's growing trend is an increased prevalence rate of postpartum depression, with Latinas facing heightened risk factors. The inadequate representation of Latinas in postpartum depression research and healthcare guidelines exacerbates their vulnerability. The prevalence of postpartum depression among Latina women makes this condition a serious public health concern. Due to insufficient research on marginalized groups, emphasis is needed on culturally competent healthcare. This literature review aims to explore the underlying factors …

Fertility Preservation: A Critical Review Of Information Available To Testicular Cancer Patients, Markram Groenewald

Honors Undergraduate Theses

Fertility preservation remains a crucial component of Testicular Cancer patients’ health-related quality of life. Significant inconsistency is present in the availability and accessibility of information related to fertility preservation for patients with Testicular Cancer. The purpose of this critical review was to determine the quantity and quality of fertility preservation provided through the websites of top cancer care centers. A total of 15 centers were chosen based on the top cancer centers from US News and World Report and expanded upon using Definitive Healthcare’s top 10 centers treating Testicular Cancer by volume. Webpages were collected and graded for accessibility of …

Monitoring Faunal Responses To Biodegradable Oyster Reef Restoration Materials With Camera Traps, Tara L. Blanchard

Honors Undergraduate Theses

Restoration of the oyster reefs has become increasingly crucial due to great population declines around the globe. Intertidal oyster reefs provide essential foraging and loafing grounds to many faunal species, including several threatened/endangered wading bird species. Biodegradable oyster reef restoration materials have been introduced to avoid potential plastic pollution from traditional materials. Studies have shown success regarding oyster recruitment rates to these materials. However, their impacts on fauna using restored oyster reefs are unknown. This project aims to evaluate oyster reef restoration using biodegradable materials to increase faunal diversity, abundance, and foraging behaviors. Camera traps were deployed to observe fauna …

The Prevalence And Determinants Of Substance Use Disorders Among Sexual Minority Adults In The United States, Katheryn Olmos

Honors Undergraduate Theses

Substance Use Disorders (SUD) continue to be a significant public health concern as drug use reaches a worldwide high. Research has consistently shown that lesbian, gay, and bisexual (LGB) individuals are at a heightened risk of having an SUD than their heterosexual counterparts. While notable work has been done to understand the factors contributing to SUD among LGB populations, there is a substantial gap in research regarding the intersection of race/ethnicity and sexual identity. This study aims to address this gap by investigating the disparities in SUD among sexual minorities across different racial/ethnic and sex groups and the determinants that …

Examining The Effects Of Artemisia Annua On Neuro2a Cells, Wesley Lim

Honors Undergraduate Theses

Artemisia annua L. is a well-known medicinal herb used in Traditional Chinese Medicine for many centuries and contains artemisinin, which exhibits antimalarial properties [1] and is a potential treatment for SARS-CoV-2 [2]. However, the neurological effect of A. annua and its compounds are poorly understood. We hypothesize that A. annua extracts and artemisinin will provide protection against oxidative stress in mouse neuronal Neuro2A cells. Superoxide dismutase 1 (SOD1) is an anti-oxidant enzyme that protects against oxidative damage [3]. Growth Arrest and DNA Damage-inducible 45 alpha (Gadd45a) is involved in DNA repair and is a common biomarker for DNA damage[4]. SOD1 …

Curanderismo And Healing: Insights From Hispanic Young Adults, Allisa Castro

Honors Undergraduate Theses

Curanderismo is a holistic form of traditional medicine primarily used by Latin American populations and Hispanic communities in the United States. This type of care focuses on several aspects of health including physical, emotional and spiritual (supernatural). Hispanics are the largest ethnic minority population in the United States and yet healthcare access to this population remains limited by various barriers including lack of insurance, legal status, language, poverty, and other structural factors. Within this context, exploring the perceptions and role of traditional medicine, like curanderismo, as a form of healthcare becomes crucial in understanding and addressing the unique healthcare needs …

Assessing Preventive Care Utilization For Cardiovascular Disease Among U.S. Latinos, Melanie Helena Paredes

Honors Undergraduate Theses

Accounting for nearly 19% of the United States population in 2020, Latinos and Hispanics represent the second largest racial/ethnic group in the United States, totaling roughly 62.1 million people. Given the growing population size and longer life expectancy estimates amongst the U.S. Latino/Hispanic community, healthcare practitioners and public health officials are increasingly emphasizing the healthcare needs and outcomes of this population. Alarmingly, current literature has highlighted significant disparities in cardiovascular disease (CVD) incidence and risk factors among U.S. Latinos/Hispanics. As CVD continues to be one of the leading causes of death amongst all racial/ethnic groups across the United States, risk …

Examining Wrack In Mosquito Lagoon To Analyze Biodiversity And Seagrass Viability, Nicole Jerrell

Honors Undergraduate Theses

Seagrass restoration of Halodule wrightii, has become crucial as seagrass coverage in the Indian River Lagoon (IRL) declined by 58% between 2011 and 2019. To understand the abundance of seagrass fragments available for natural recruitment and restoration, we tracked the abundance of viable fragments found in the wrack in Mosquito Lagoon. Wrack is plant material, including seagrass fragments, mangrove propagules, and detritus. Seagrass fragments were considered viable if the fragment had an apical meristem present. Replicate samples were collected from 5 locations every two weeks, starting in September 2022 and ending in September 2023, and the samples were processed …

Functional Verification Of Additively Manufactured Metallopolymer Structures For Structural Electronics Design, Nathan D. Singhal

Honors Undergraduate Theses

As an attempt to improve the overall cost-effectiveness and ease of structural electronics manufacturing, this study characterizes the mechanical and electrical responses of structures which are fabricated from a novel metallopolymer composite material by fused deposition modeling as they are subjected to quasi-static, uniaxial mechanical tension. Baseline values of tensile properties and electrical resistivity were first obtained via ASTM D638-22 standard testing procedures and linear sweep voltammetry (LSV), respectively. A hybrid procedure to measure in-situ mechanically dependent electrical behavior was subsequently developed and implemented. The mechanical and electromechanical testing was followed by the derivation of stochastic values for several mechanical …

Tracking The Reaction Networks Of Criegee Intermediates Formed In The Ozone-Assisted Oxidation Reactions Of C5 Acyclic And Endocyclic Alkenes, Arden M. Floyd

Honors Undergraduate Theses

Uni- and bi-molecular reactions involving Criegee intermediates (CIs), characteristic to alkene-ozone reactions, play an important role in synthetic organic, atmospheric, and combustion chemistry. However, difficulty in detecting key intermediates has prevented a thorough understanding of the details of the ozonolysis mechanism. To gain new insights into how alkene structure affects the CI network, the ozone assisted oxidation reactions of trans-2-pentene and cyclopentene are investigated between 320 K and 760 K in an atmospheric pressure jet stirred reactor (JSR). Molecular-beam mass spectrometry in conjunction with single photon tunable synchrotron VUV radiation is used to identify elusive intermediates by means of …

Exploring The Link Between Neurocognitive Function And Long Covid: A Comprehensive Review, Dinamaris Aguilar

Honors Undergraduate Theses

The intent of this thesis is to provide an in-depth overview of the neurological manifestations associated with long COVID. The review aimed to assess the cognitive functioning symptoms associated with SARS-CoV-2 post-infection (PASC), investigate the potential mechanisms by which SARS-CoV-2 affects the nervous system, contributing to cognitive fatigue, brain fog, and cognitive dysfunction, and explore the parallels between SARS-CoV-2 and Alzheimer’s Disease. Neuroinflammation emerges as a shared element among these mechanisms, significantly impacting cognitive function. The parallels between COVID-19 and Alzheimer's Disease offer insights into how Alzheimer's affects cognition, aiding in understanding COVID-19's impact. The review underscores a notable gender …

The Battle Over Diversity, Equity, And Inclusion And Critical Race Theory In Florida: A Case Study On The Stop W.O.K.E. Act, Grace Anne Castelin

Honors Undergraduate Theses

Accelerating from 2022 and continuing through 2024, the state of Florida has experienced significant policy changes, particularly within the realm of higher education and affairs of diversity, equity, and inclusion (DEI). Many progressive officials, experts, and activists assert arguments that the state is on the verge of evolving into an authoritarian regime while many illiberal policies are being produced through the Florida legislature and current executive leadership—social and economic sectors are consequently threatened in order to maintain political oppression. The Stop W.O.K.E. Act has served as a catalyst for shifting the state's political stance on DEI, culminating in a chain …

The Effects Of Nanobubbles For Gene Delivery For Osteoporosis Treatment, Abel Córdova Flores

Honors Undergraduate Theses

In recent years, the field of nanomedicine has provided promising alternatives to traditional ways of gene and drug delivery, such as nanobubbles instead of viral vectors. Manufacturing these nanomaterials is cost-effective and tends to be safer than previous forms of treatment for clinical use. In the realm of osteoporosis, a disease based around a higher rate of bone resorption to bone formation, leads to weak and brittle bones, leaving sufferers at risk for fractures, which are sudden and unexpected. These fractures are estimated to cost USD 22 Billion annually in the US alone. Reports show a significant effect on the …

Adaptation Of A Commercially Available Galvanic Skin Response Sensor To Measure Respiration Across The Chest For Heart Rate Variability Monitoring, Breno C. Dobal

Honors Undergraduate Theses

Heart rate variability (HRV) is a naturally occurring cardiovascular phenomenon referring to the changing timing between consecutive heartbeats. The connection between HRV and overall cardiovascular health and autonomic nervous system function has been well established through prior research and well documented in existing literature. The existing studies, however, included shorter HRV subject recording session, using traditional HRV monitoring methods that do not typically combine electrocardiogram (ECG), seismocardiogram (SCG) and galvanic skin response (GSR) respiration monitoring. The inclusion of longer HRV subject recording may allow for further insight on the possible effects of given observable biological phenomenon on HRV.

The current …

Experiences Of Healing With Ayahuasca In The United States, Rebecca Galinanes

Honors Undergraduate Theses

Ayahuasca is a psychedelic brew originating from the Amazon in South America. Commonly associated with religious use among indigenous and mestizo populations, ayahuasca has made its way to the United States, where it is currently criminalized as a Schedule I drug. Nevertheless, a church in the United States provides ayahuasca to its members as both a sacrament and tool for healing through spiritual retreat weekends. Based on participant observation and semi-structured interviews with church members, volunteers, and staff in 2023, this thesis examines how members perceived the healing they experienced during multiple ayahuasca ceremonies and interactions with church volunteers and …

The Implications Of Artificial Intelligence In The Criminal Justice System, Natalie Garay

Honors Undergraduate Theses

This thesis focuses on artificial intelligence's recent implications on the criminal justice system regarding its admissibility as evidence in civil and criminal cases. One of the main concerns surrounding artificial intelligence is determining the validity of AI application; application refers to the accuracy "AI measures, classifies, or predicts what it is designed to" (Article: Artificial Intelligence as Evidence by Paul W. Grimm, Maura R. Grossman & Gordon V.Cormack.(https://scholarlycommons.law.northwestern.edu/cgi/viewcontent.cgi?article=1349&context=njtip). Privacy law will also be analyzed in this analysis. Is evidence recorded without the individual's consent or knowledge acceptable in determining an individual's guilt? This analysis will primarily focus on …

At The Heart Of Nursing: A Literature Review On Health Literacy Education In Nursing Curricula And Preparation For Patient Teaching Encounters, Samantha Garcia

Honors Undergraduate Theses

Background: Health literacy is defined as one’s ability to find, comprehend, and utilize information to make health decisions (Office of Disease Prevention and Health Promotion, n.d.). Globally, nursing students are exposed to the concept of health literacy during their degree-seeking years, yet no formal health literacy education exists across nursing curricula in pre-licensure programs at the associate and bachelor levels. This lack of standardization and non-emphasis of health literacy as a formal topic within education has contributed to poor provider performance and, in turn, low health literacy rates that may lead to suboptimal patient outcomes.

Significance: Studies have found that …

Ratón Pérez: A Translation Of The Spanish Tooth Fairy Legend, Sasmeta Giriraj

Honors Undergraduate Theses

The Ratón Pérez story is an essential landmark in the childhoods of many, especially in Latin American culture. The tale serves as a tool to help children with the anxiety and pain that may be associated with loss of their primary teeth and creates an exciting tradition for them to partake in. Despite the prevalence of this story among Hispanic populations, the last translation of it into English was by Ada Margarete Smith, Lady Moreton (1914). Given the large oral health disparity between the Hispanic population and other ethnic groups in the United States, a more updated translation may serve …

Identifying The Use Of Turtles And Tortoises At The Prehistoric Penny Site At Cape Canaveral, Alexandria Griffin

Honors Undergraduate Theses

As people live in an area, they leave behind an assortment of cultural items they once utilized. Some of these items may include pottery or bones from animals they used as food. Analysis of these bones can give a glimpse into how they managed their resources in the environment around them, including which ecosystems they chose to exploit, and which taxa they prioritized for consumption or cultural purposes. The Indian River Lagoon in Florida is a diverse costal lagoon with many various overlapping ecosystems and ecotones available for prehistoric peoples to utilize. Comparing the frequency of taxa representing different local …

Motivations For Retaliatory Aggression On Social Media Among Borderline Personality Endorsers, Hannah Grimes

Honors Undergraduate Theses

Social media has become a popular way of connecting with people, but it has also led to an increase in cyber aggression. Borderline Personality Disorder (BPD) is a condition that is characterized by retaliatory aggression, difficulty in interpersonal relationships, and high impulsivity. Those who endorse BPD symptoms experience unstable interpersonal relationships and struggle to maintain connections with others which can lead to problematic behaviors on social media like retaliatory aggression. Understanding the motivations behind those behaviors can help inform the experiences of the diagnosed population, mitigate problematic behaviors, and facilitate healthy social relationships. This study aims to explore the motivations …

Masculinity And Political Discourse: A Critical Analysis Of European Leaders, Taylor R. Haycock

Honors Undergraduate Theses

This project examines how European leaders of autocratic and democratic nations engage with masculinity discourses in their public speeches. Do authoritarian leaders use masculinity in a different way than democratic leaders? I answer this question by completing a critical discourse analysis of speeches from Vladimir Putin, Recep Tayyip Erdoğan, Boris Johnson, and Emmanuel Macron, the leaders of Russia, Turkey, the United Kingdom, and France, respectively. The speeches were publicized from July 2019 to September 2022, when all four leaders were simultaneously in office. I found that a similar rhetorical strategy focusing on dominance and strength was used across regime types …