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2024

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Corporate Social Responsibility, Economic, Ethical-Legal, And Philanthropic Performances In Ghanaian Banks Using Big Data Analytics, Mohammed Alhassan Adams Dec 2024

Corporate Social Responsibility, Economic, Ethical-Legal, And Philanthropic Performances In Ghanaian Banks Using Big Data Analytics, Mohammed Alhassan Adams

Walden Dissertations and Doctoral Studies

Corporate social responsibility (CSR) is becoming increasingly essential for Ghanaian banks to reconcile financial growth with ethical, legal, and civic obligations amid escalating societal expectations. The specific research problem was that the extent to which Ghanaian banks employed big data analytics (BDA) to boost multidimensional CSR performance encompassing economic, ethical-legal, and philanthropic dimensions was unknown. The purpose of this quantitative correlational study was to examine the potential impacts of BDA use and overall CSR performance on Ghanaian banks’ economic, ethical-legal, and philanthropic dimensions of CSR. Using stakeholder theory and a resource-based view, BDA was applied as a strategic tool for …


We The People, But Not You: The Eighth Circuit Says Undocumented Immigrants Are Not Part Of “The People” Who May Bear Arms, Caleb Kearney Dec 2024

We The People, But Not You: The Eighth Circuit Says Undocumented Immigrants Are Not Part Of “The People” Who May Bear Arms, Caleb Kearney

Villanova Law Review (1956 - )

No abstract provided.


Non(Belonging) Of Ethnic Minority Communities In Britain: Researcher Reflections, Suparna Bagchi Dec 2024

Non(Belonging) Of Ethnic Minority Communities In Britain: Researcher Reflections, Suparna Bagchi

School of Law, Humanities and Social Sciences

Introduction. There is limited research concerning the experiences of people belonging to ethnic minority communities in predominantly White places (Cline et al., 2002; Garland & Chakraborti, 2006; Scourfield & Davies, 2005). Predominantly White places are those that are inhabited by people from ethnic minority communities with restricted communication with places of worship, cultural institutions and educational norms of their communities, for which they do not feel included (DfES, 2004). In these places, these people not only reside in an invisible state (Bhopal, 2014), but their voices also stay unheard (Chakraborti & Garland, 2004) in official records (Pac-Soo & Taylor, 2023). …


Muqarnas In Damascus: A Forgotten Treasure’S History, Inception And Geometry, Nahed Jawad Chakouf Dec 2024

Muqarnas In Damascus: A Forgotten Treasure’S History, Inception And Geometry, Nahed Jawad Chakouf

All Works

The architecture of the Islamic world encompasses both religious and secular buildings that are unified by the use of a common architectural language, which includes architectural elements such as minarets, domes and arches, ornamental details, and vaulting with the use of muqarnas. The study provides a broad overview of the development of Islamic architecture, focusing on Damascus, the early Islamic period, the mid-Islamic period and the late Islamic period. The late Islamic period includes Ottoman art, with architecture influenced by Byzantine, Persian, Armenian, and Mamluk artefacts, but differs from their predecessors. The researcher undertook a geometric analysis of the muqarnas …


Epithelial Barrier Hypothesis: A Systematic Review, Krishna Patel, Peter Lio Dec 2024

Epithelial Barrier Hypothesis: A Systematic Review, Krishna Patel, Peter Lio

Student Publications

Background

The epithelial barriers, which include the skin, the gut, and the respiratory lining, play a crucial role in protecting the body from pathogens and environmental threats. Many harmful toxins are increasingly part of modern life. The increase in usage of these damaging agents in conjunction with the increase in allergic inflammatory conditions suggests that the “epithelial barrier hypothesis”—the concept that damage to the epithelia by external agents can result in dysbiosis, inflammation, and allergy—may explain the rise in these conditions seen in the developed world.

Objective

We sought to assess the evidence for the epithelial barrier hypothesis, with particular …


Population-Based Study Of The Epidemiology Of Stiff Person Syndrome In A Large Colorado-Based Health System, Paul Daniel Crane, Stefan Sillau, Renee Dreher, Rikki Fix, Phillip Winters, Russell Van Coevering, Eric Engebretson, Brooke Valdez, Elizabeth Matthews, Kavita V. Nair, Aaron M. Carlson, Amanda L. Piquet Dec 2024

Population-Based Study Of The Epidemiology Of Stiff Person Syndrome In A Large Colorado-Based Health System, Paul Daniel Crane, Stefan Sillau, Renee Dreher, Rikki Fix, Phillip Winters, Russell Van Coevering, Eric Engebretson, Brooke Valdez, Elizabeth Matthews, Kavita V. Nair, Aaron M. Carlson, Amanda L. Piquet

Student Publications

Background and objectives: Stiff person syndrome spectrum disorder (SPSD) is a rare autoimmune disorder characterized by progressive muscle stiffness and painful spasms with an estimated prevalence of 1-2 cases per million people. Population-based epidemiologic studies are lacking because of both poor patient capture and the lack of standardized diagnostic criteria. Objectives of this study were to describe the incidence and prevalence of SPSD within the University of Colorado Health (UCH) system and apply previously proposed published criteria for SPSD within this population.

Methods: We queried Health Data Compass, an electronic health data repository for a large academic health care system, …


Matter Of Syllman V. New York State Div. Of Hous. & Community Renewal Dec 2024

Matter Of Syllman V. New York State Div. Of Hous. & Community Renewal

All Decisions

In this Article 78 proceeding, the tenant challenged a rent increase granted for a major capital improvement involving roof and facade repairs. The DHCR's determination was upheld as rational and not arbitrary or capricious. The court reaffirmed that administrative decisions must stand unless lacking sound reasoning or factual support. Judgment dismissed the tenant's petition, validating the rent increase for the landlord.


Targeted Degradation Of Oncogenic Krasg12v Triggers Antitumor Immunity In Lung Cancer Models, Dezhi Li, Ke Geng, Yuan Hao, Jiajia Gu, Saurav Kumar, Annabel T Olson, Christina C Kuismi, Hye Mi Kim, Yuanwang Pan, Fiona Sherman, Asia M Williams, Yiting Li, Fei Li, Ting Chen, Cassandra Thakurdin, Michela Ranieri, Mary Meynardie, Daniel S Levin, Janaye Stephens, Alison Chafitz, Joy Chen, Mia S Donald-Paladino, Jaylen M Powell, Ze-Yan Zhang, Wei Chen, Magdalena Ploszaj, Han Han, Shengqing Stan Gu, Tinghu Zhang, Baoli Hu, Benjamin A Nacev, Medard Ernest Kaiza, Alice H Berger, Xuerui Wang, Jing Li, Xuejiao Sun, Yang Liu, Xiaoyang Zhang, Tullia C Bruno, Nathanael S Gray, Behnam Nabet, Kwok-Kin Wong, Hua Zhang Dec 2024

Targeted Degradation Of Oncogenic Krasg12v Triggers Antitumor Immunity In Lung Cancer Models, Dezhi Li, Ke Geng, Yuan Hao, Jiajia Gu, Saurav Kumar, Annabel T Olson, Christina C Kuismi, Hye Mi Kim, Yuanwang Pan, Fiona Sherman, Asia M Williams, Yiting Li, Fei Li, Ting Chen, Cassandra Thakurdin, Michela Ranieri, Mary Meynardie, Daniel S Levin, Janaye Stephens, Alison Chafitz, Joy Chen, Mia S Donald-Paladino, Jaylen M Powell, Ze-Yan Zhang, Wei Chen, Magdalena Ploszaj, Han Han, Shengqing Stan Gu, Tinghu Zhang, Baoli Hu, Benjamin A Nacev, Medard Ernest Kaiza, Alice H Berger, Xuerui Wang, Jing Li, Xuejiao Sun, Yang Liu, Xiaoyang Zhang, Tullia C Bruno, Nathanael S Gray, Behnam Nabet, Kwok-Kin Wong, Hua Zhang

Faculty, Staff and Student Publications

Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most frequently mutated oncogene in lung adenocarcinoma, with G12C and G12V being the most predominant forms. Recent breakthroughs in KRASG12C inhibitors have transformed the clinical management of patients with the G12C mutation and advanced our understanding of the function of this mutation. However, little is known about the targeted disruption of KRASG12V, partly due to a lack of specific inhibitors. Here, we leverage the degradation tag (dTAG) system to develop a KRASG12V-transgenic mouse model. We explored the therapeutic potential of KRASG12V degradation and characterized its effect on the tumor microenvironment (TME). …


Generative Ai In Shariah Advisory In Islamic Finance: An Experimental Study, Muhammad Noman Jokhio, Muhammad Asif Jaffer Dec 2024

Generative Ai In Shariah Advisory In Islamic Finance: An Experimental Study, Muhammad Noman Jokhio, Muhammad Asif Jaffer

Business Review

Islamic banks adhere strictly to Shariah principles in all operations and offerings, creating a demand for experts proficient in Shariah-compliant banking and finance. This study investigates the potential of using generative AI, specifically Large Language Models (LLMs), to provide Shariah advisory in complex Islamic financing scenarios. The research evaluates general purpose public LLMs—such as ChatGPT, Gemini, and Meta AI—on their ability to identify Shariah compliance issues, cite relevant Shariah references, and propose actionable guidance for resolving compliance challenges in complex Islamic financing scenarios. A qualitative approach was used. The experimental study involved creation of complex, realistic financing scenarios requiring Shariah …


Engagement With Professional Stakeholders In Healthcare Research—The Case Of The Dementia Personalised Care Team (D-Pact) Project In The United Kingdom, Basharat Hussain, Hannah Wheat, Tomasina M. Oh, Richard Byng Dec 2024

Engagement With Professional Stakeholders In Healthcare Research—The Case Of The Dementia Personalised Care Team (D-Pact) Project In The United Kingdom, Basharat Hussain, Hannah Wheat, Tomasina M. Oh, Richard Byng

Peninsula Medical School

Introduction: In this viewpoint we highlight a gap in the literature relating to the involvement of professional stakeholders in healthcare evaluation research. Method: Using the Dementia—PersonAlised Care Team (D-PACT) project as an example, we illustrate how professional stakeholder work can serve various functions, from understanding commissioning and policy context to contributing to detail of intervention components. Outcome: We argue that identifying these project-specific functions can help researchers to effectively plan when, how and for whom they will engage in professional stakeholder work across the course of an evaluation. In addition, we call for further evidence-based guidance and sufficient allocation of …


Emata: A Toolbox For The Automatic Extraction And Modeling Of Arterial Inputs For Tracer Kinetic Analysis In [18f]Fdg Brain Studies, Mattia De Francisci, Erica Silvestri, Andrea Bettinelli, Tommaso Volpi, Manu S Goyal, Andrei G Vlassenko, Diego Cecchin, Alessandra Bertoldo Dec 2024

Emata: A Toolbox For The Automatic Extraction And Modeling Of Arterial Inputs For Tracer Kinetic Analysis In [18f]Fdg Brain Studies, Mattia De Francisci, Erica Silvestri, Andrea Bettinelli, Tommaso Volpi, Manu S Goyal, Andrei G Vlassenko, Diego Cecchin, Alessandra Bertoldo

2020-Current year OA Pubs

PURPOSE: PET imaging is a pivotal tool for biomarker research aimed at personalized medicine. Leveraging the quantitative nature of PET requires knowledge of plasma radiotracer concentration. Typically, the arterial input function (AIF) is obtained through arterial cannulation, an invasive and technically demanding procedure. A less invasive alternative, especially for [

METHODS: To assess the toolbox generalizability and present example outputs, EMATA was applied to brain [

RESULTS: EMATA consistently performs IDIF extraction across all datasets, despite differences in scanners and acquisition protocols. Remarkably high agreement is observed when comparing Patlak's K

CONCLUSION: EMATA proved adaptability to different datasets characteristics and …


Cover Vol. 52 No. 4, ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาฯ Dec 2024

Cover Vol. 52 No. 4, ศูนย์นวัตกรรมทางการศึกษา สื่อสิ่งพิมพ์ และสื่อออนไลน์ จุฬาฯ

Journal of Education Studies

No abstract provided.


Exploring Anxiety, Uncertainty Perception, Treatment Experiences, And Coping Strategies: An Interpretative Phenomenological Analysis, Aysun Parlar Yazici, Alyson Norman, Alison Bacon Dec 2024

Exploring Anxiety, Uncertainty Perception, Treatment Experiences, And Coping Strategies: An Interpretative Phenomenological Analysis, Aysun Parlar Yazici, Alyson Norman, Alison Bacon

School of Psychology

No abstract provided.


Re: Silver Bow Creek Butte Area Npl Site Spring Semi-Annual 2024 Butte Priority Soils Operable Unit Interim Site-Wide Groundwater Monitoring Data Report. Consent Decree- Civil Action No. Cv 89-039-Bu-She, Josh Bryson Dec 2024

Re: Silver Bow Creek Butte Area Npl Site Spring Semi-Annual 2024 Butte Priority Soils Operable Unit Interim Site-Wide Groundwater Monitoring Data Report. Consent Decree- Civil Action No. Cv 89-039-Bu-She, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey Dec 2024

Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey

2020-Current year OA Pubs

Pseudoachondroplasia (PSACH), a severe dwarfing condition characterized by impaired skeletal growth and early joint degeneration, results from mutations in cartilage oligomeric matrix protein (COMP). These mutations disrupt normal protein folding, leading to the accumulation of misfolded COMP in chondrocytes. The MT-COMP mouse is a murine model of PSACH that expresses D469del human COMP in response to doxycycline and replicates the PSACH chondrocyte and clinical pathology. The basis for the mutant-COMP pathology involves endoplasmic reticulum (ER) stress signaling through the PERK/eIF2α/CHOP pathway. C/EBP homologous protein (CHOP), in conjunction with a TNFα inflammatory process, upregulates mTORC1, hindering autophagy clearance of mutant COMP …


Lower-Intensity Cpx-351 Plus Venetoclax Induction For Adults With Newly Diagnosed Aml Unfit For Intensive Chemotherapy, Geoffrey L Uy, Vinod Pullarkat, Praneeth Baratam, Robert K Stuart, Roland B Walter, Eric S Winer, Qi Wang, Stefan Faderl, Divya Chakravarthy, Diane Menno, Ronald S Cheung, Tara L Lin Dec 2024

Lower-Intensity Cpx-351 Plus Venetoclax Induction For Adults With Newly Diagnosed Aml Unfit For Intensive Chemotherapy, Geoffrey L Uy, Vinod Pullarkat, Praneeth Baratam, Robert K Stuart, Roland B Walter, Eric S Winer, Qi Wang, Stefan Faderl, Divya Chakravarthy, Diane Menno, Ronald S Cheung, Tara L Lin

2020-Current year OA Pubs

Preclinical data suggest a rationale for combining CPX-351, a dual-drug liposomal encapsulation of daunorubicin and cytarabine, with venetoclax, a B-cell lymphoma-2 inhibitor. This phase 1b study evaluated lower-intensity CPX-351 combined with venetoclax in adults with acute myeloid leukemia (AML) considered unfit/ineligible for intensive chemotherapy. In a dose-exploration phase using a 3+3 design, patients received stepwise dosing of CPX-351 IV on days 1 and 3 plus venetoclax 400 mg orally on days 2 to 21 per cycle to determine the recommended phase 2 dose (RP2D) for this combination. During the expansion phase, additional patients received CPX-351 plus venetoclax at the identified …


Ai Code Canaries For Proactive Source Code Leak Detection, Ray Van Hoose Dec 2024

Ai Code Canaries For Proactive Source Code Leak Detection, Ray Van Hoose

Defensive Publications Series

This disclosure describes AI Code Canaries, a novel approach to source code protection using dynamically generated, context-aware code snippets (canaries) embedded within the codebase to proactively detect unauthorized code leakage. This method addresses limitations of traditional watermarking and other techniques by offering finer-grained detection, increased resilience to code transformations, and immediate leak identification. Unlike traditional watermarking methods, which struggle with fine-grained detection and are vulnerable to code transformations, AI Code Canaries offer granular detection of even small code fragments, increased resilience through dynamic generation, and proactive leak identification.


Providing Enhanced Learning In Llms By Associating Data With Role-Based Source Information, Laxmi Mukund, Shraddha S K Dec 2024

Providing Enhanced Learning In Llms By Associating Data With Role-Based Source Information, Laxmi Mukund, Shraddha S K

Defensive Publications Series

In today's fast-paced world, the rapid introduction of new product features necessitates accurate and timely documentation. Traditional manual documentation methods are inefficient, error-prone, and often result in outdated information. Techniques are presented herein to address these challenges by leveraging Large Language Models (LLMs) to automate the generation of precise and reliable documents by associating data with well-defined role-based source information. The impact of this solution goes beyond generating documentation for new features; it can also be extended to enable targeted stakeholder interactions, to identify speakers in recorded conversations, and to classify unclassified dialogues.


Nonprofit Spotlight: Choice Humanitarian, Erica Jensen Dec 2024

Nonprofit Spotlight: Choice Humanitarian, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.


Research Summaries: Access To Education, Erica Jensen Dec 2024

Research Summaries: Access To Education, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.


Full Issue: Access To Education, Angie Holzer Dec 2024

Full Issue: Access To Education, Angie Holzer

Journal of Nonprofit Innovation

No abstract provided.


The Anxious Generation, How The Great Rewiring Of Childhood Is Causing Epidemic Of Mental Illness, Jay Nathan Dec 2024

The Anxious Generation, How The Great Rewiring Of Childhood Is Causing Epidemic Of Mental Illness, Jay Nathan

Journal of Global Awareness

No abstract provided.


Public Disclosure And Its Impact On Ceo Compensation: Evidence Of Media Influence, Xin Zhao Dec 2024

Public Disclosure And Its Impact On Ceo Compensation: Evidence Of Media Influence, Xin Zhao

Journal of Global Awareness

I examine the effect of the AFL-CIO executive paywatch identification on future CEO compensation. My findings indicate that the public disclosure of CEO compensation has a negative impact on subsequent changes in CEO pay. Additionally, I find that CEOs with ex-ante overpayment have experienced changes in their subsequent compensation. This paper contributes to the literature by documenting that firms respond to negative press coverage of CEO compensation, even after controlling for the mean reversion effect associated with high CEO pay.


Effects Of Monetary Policy On Economic Growth: Evidence From Some Developing And Developed Economies, Collins Anosike Dec 2024

Effects Of Monetary Policy On Economic Growth: Evidence From Some Developing And Developed Economies, Collins Anosike

Journal of Global Awareness

The study examined the effects of monetary policy on the economic growth of some developing and developed economies. This study selected 33 countries grouped into 11 each as first-group, second-group, and third-group countries and showed how monetary policy has influenced their economic growth in the past 40 years, capturing the economic growth performances before and after the global financial crisis. This study is unique because it captures a broader range of countries compared to previous studies, uses updated data, and shows how monetary policy is transmitted through bank lending and financial intermediation. Furthermore, we use panel data and employ fixed …


Assessing State Laws And Regulations On Radon In Us Childcare Centers, Benjamin Poku, Sayed Hussaini Dec 2024

Assessing State Laws And Regulations On Radon In Us Childcare Centers, Benjamin Poku, Sayed Hussaini

Journal of Global Awareness

In the US, radon is the second most significant contributor to lung cancer, following smoking. Despite this, there is a notable absence of state-level measures and guidelines aimed at managing and mitigating the risks associated with exposure to radon gas. The objective of this research was to investigate whether state-level laws regarding radon in childcare centers have a correlation with the proportion of counties in each state that fall under radon zone 1 (with levels exceeding 4 pCi/L). The research method was secondary analysis. Data was gathered from multiple sources, including the EPA radon website, academic journals, official state government …


Takaful Insurance Industries In Supporting Sustainable Socio-Economic Development In Indonesia, Fera Widyanata, Rasyida Pertiwi, Ahmad Syathiri Dec 2024

Takaful Insurance Industries In Supporting Sustainable Socio-Economic Development In Indonesia, Fera Widyanata, Rasyida Pertiwi, Ahmad Syathiri

Journal of Global Awareness

Over the past four years, the demand for Takaful (Islamic insurance) among Indonesians has risen. Health Takaful has emerged as the most popular, followed by educational Takaful. Health and education are parts of the Human Development Index (HDI) and are closely related to building a stronger foundation for Indonesia's economic development. This study aims to enhance the Islamic finance ecosystem's impact on achieving SDGs, focusing on health (SDG 3), education (SDG 4), and economic growth (SDG 8), which are crucial for Indonesia's development. It discovers a causal relationship between the takaful industry and improvements in the health sector and …


The Mediation Of Financial Behavior To Financial Literacy And Spending Habits Of Gen Z: An Exploratory Factor Analysis, Joel Mark Rodriguez, Del Carmen Labong, Lourdes Palallos Dec 2024

The Mediation Of Financial Behavior To Financial Literacy And Spending Habits Of Gen Z: An Exploratory Factor Analysis, Joel Mark Rodriguez, Del Carmen Labong, Lourdes Palallos

Journal of Global Awareness

The study aims to explain the relationship of financial literacy with spending habits and behavior. Financial behavior is a mediator of Generation Z. Financial literacy is a very important dimension in making financial decisions, and this research highlighted the direct and indirect impacts that financial literacy exerts on spending behavior. Data is collected from 317 respondents using a structured questionnaire measuring financial literacy, financial behavior, and spending behavior. Correlation, regression, mediation analysis, and Structural Equation Modeling have been used in evaluating these relationships. Financial literacy directly reflects a strong relationship with spending behavior, and its coefficient is 1.167. Financial behavior, …


A Study Abroad Immersion And Reflection Of American Liberal Arts Students In Cyprus, Mark Reimer, Yiannis Miralis Dec 2024

A Study Abroad Immersion And Reflection Of American Liberal Arts Students In Cyprus, Mark Reimer, Yiannis Miralis

Journal of Global Awareness

Ensemble tours abroad, with a liberal arts focus, provide a rich, unique, and highly educational opportunity to make music while experiencing the history, people, language, and culture of another country. Pre-tour preparation, however, requires research and a trusted relationship between the director and the host to ensure that the musicians in both countries enjoy the same degree of excitement and desire to learn from one another. The following article is research that was conducted for an American college wind ensemble tour to Cyprus. In addition to reviewing several books and journals, the authors listened to hours of classical, folk, and …


Brexit And The Spillover Phenomenon: Scotland, Northern Ireland, And Gibraltar, Timea Varga Dec 2024

Brexit And The Spillover Phenomenon: Scotland, Northern Ireland, And Gibraltar, Timea Varga

Journal of Global Awareness

In my research, I examined the consequences of Brexit and the spillover phenomenon. Even though the United Kingdom left the European Union on 31 December 2020 with a deal, the resulting challenges are not solved at all in 2024 either – Brexit has brought to the surface such conflicts that London considered dealt with a long time ago. However, questions of autonomy and independence are not so easy to resolve; they have their roots in history, and in this uncertain situation, they came to the fore again.

Northern Ireland, Gibraltar, and Scotland have always meant sources of conflict for the …


Notes From The Editor, Jay Nathan Dec 2024

Notes From The Editor, Jay Nathan

Journal of Global Awareness

No abstract provided.