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Loper Bright In A Larger Interpretive Perspective: Is This Justice Scalia’S Court Anymore?, Victoria Frances Nourse

Georgetown Law Faculty Publications and Other Works

Loper Bright Enterprises v. Raimondo has left administrative lawyers agog: Could the Supreme Court really reverse the “goliath” known as Chevron deference? For those who study the Court’s interpretive landscape more broadly, however, Chevron reversal may not be as unexpected as administrative lawyers believe. This Article will look at Loper Bright by linking three notable interpretive developments: the major questions doctrine, Chevron skepticism, and strict constructions of statutory text. These developments share the same risk: the Court is imposing a new “clarity tax” on both Congress and administrative agencies. Having said this, others’ grave worries about changes in Chevron are …

Breast Tissue As A Local Drug Reservoir For Anticancer Therapy In Breast Cancer, Saniia Shchinar

Electronic Theses and Dissertations

Breast cancer, particularly the estrogen receptor-positive (ER+) subtype, remains a formidable challenge in oncology. Traditional oral therapies for ER-positive breast cancer, such as selective estrogen receptor modulators (SERMs) like Tamoxifen (TAM) and Toremifene (TOR), often encounter issues related to limited bioavailability, metabolic complications, and significant systemic side effects. These side effects include the risk of blood clots, hot flashes, vaginal dryness, menstrual cycle disruptions, and uterus cancer, which can hinder long-term adherence to preventive therapy. The exploration of local drug delivery into breast tissue presents a promising alternative to tackle these challenges. In this study, we explored the feasibility of …

Delivery Of Gemcitabine, Stearoyl Gemcitabine And Paclitaxel Through Plga Nanoparticles And Its Effect On The Desmoplasia Of Pancreatic Cancer Spheroids, Rishabh Bahl

Electronic Theses and Dissertations

Pancreatic cancer is one of the deadliest cancers to treat. The primary cause for the drug resistance is the dense extracellular matrix (ECM) that surrounds the tumor and restricts blood supply. Gemcitabine (GEM) and paclitaxel (PTX) are drugs that are clinically used in the treatment of pancreatic cancer. GEM, however, is rapidly metabolized by cytidine deaminase (CDA) and eliminated from the body, and paclitaxel is a substrate for P- glycoprotein (P-gp) efflux receptors. Drug delivery using nanoparticles has been reported to help improve drug half-lives and bypass efflux receptors. This thesis aims to encapsulate PTX in PLGA nanoparticles (PTX-NP) and …

Role Of Interferon Induced Transmembrane Protein 3 (Ifitm3) And Neural Precursor Cell Expressed Developmentally Down Regulated Protein 4 (Nedd4) In Seneca Virus A (Sva) Replication, Shamiq Aftab

Electronic Theses and Dissertations

In this study, we studied the role of IFITM3 in SVA replication in vitro by silencing the endogenous IFITM3 in NCI-H1299 cells. An average of 1.94-fold increase in SVA VP2 expression and an average of 4.4-fold increase in supernatant virus titer was observed after 24h SVA isolate SD15-26 infection. We have indeed observed an increase in viral mRNA copies by an average of 5-fold in IFITM3 silenced NCI-H1299 cells at 8 hpi indicating that IFITM3 restricts SVA replication post virus attachment and entry. A positive correlation between interferon-alpha induced IFITM3 upregulation and reduced SVA replication was observed. To further confirm …

Understanding The Education Profiles Of Eight Latin American Countries, Girl Center

Adolescents and Young People

Despite significant progress in improving primary enrollment and attainment for girls in low- and middle-income countries (LMICs) in recent years, gender disparities in education persist and hinder opportunities for girls. Educational attainment for girls has plateaued in numerous countries, with only a few making significant strides in narrowing the gender gap. Moreover, attainment alone does not always translate to improved learning. Gender-related barriers such as school environments that are not conducive to learning and the experience of violence, early and forced marriage, and early childbearing, as well as a lack of support for girls’ education impede attainment and learning. The …

Xenophobia, The Global War On Terror, And Refugee Policy In The United States, Canada, And Western Europe, Chloe Lopez

UNF Graduate Theses and Dissertations

Xenophobia has oscillated in intensity in the United States, Canada, and Western Europe since the late eighteenth century. This pattern of fear of immigrants and refugees being harbingers of violence and criminal activity establishes itself throughout the modern history of the United States, Canada, and Western Europe despite much evidence to the contrary. In the twentieth century, the prevailing argument surrounding the creation of xenophobia centered around economics. This divergence from twenty-first century patterns can be attributed to the Global War on Terror increasing alienation of refugees and immigrants through mythmaking and the structural securitization of immigration in the United …

Examining Teachers' Perceptions Of Culturally Responsive Teaching Practices And The Impact On The Academic And Social-Emotional Success Of Black And Brown Boys In Voluntary Prekindergarten Classrooms: A Qualitative Study, Stephanie Gomez Jackson

UNF Graduate Theses and Dissertations

The purpose of this study was to explore voluntary pre-kindergarten (VPK) teachers’ perspectives regarding the theory of culturally responsive pedagogy. This study also sought to understand how teachers implement culturally responsive teaching practices in VPK classrooms and their perceptions of how culturally responsive teaching impacts the academic and social-emotional success of Black and Brown male students. The study was conducted using a qualitative, phenomenological methodology. Gay’s (2018) pillars of culturally responsive teaching were used as the conceptual framework to explore the cultural characteristics, experiences, and perspectives of voluntary prekindergarten (VPK) teachers. Data collection tools included (1) two recorded semi-structured interviews, …

Navigating Unknown Complexities: School Superintendent Perspectives Of Leading During Covid, Jamie Mikelle Pearson Iannone

UNF Graduate Theses and Dissertations

The COVID-19 pandemic has presented unprecedented challenges for educational leaders, particularly superintendents, who have been tasked with navigating the complexities of leading during a global crisis. In this study I explored the perspectives of superintendents on leading during COVID-19 and examined the application of Complexity Leadership Theory in educational settings. Through semi-structured interviews with superintendents from diverse districts, I investigated the strategies and approaches employed by educational leaders to address the multifaceted challenges posed by the pandemic. I also examined the impact of Complexity Leadership Theory on educational practices and outcomes during the pandemic. The findings suggest that superintendents have …

A Clustering-Based Approached To Analyze Impacts Of Digital Divide On Undercounting Issues In Census In Florida, Partha Protim Datta

UNF Graduate Theses and Dissertations

According to the US Census Bureau 2020 data, Florida is one of the six states where the population was undercounted. The census in the US is conducted every ten years and plays a pivotal role in shaping government representation, resource allocation, policy making and federal assistance distribution. Consequently, undercounting of population impacts demographic equality, potentially leading to inequitable distribution of resources. The state of Florida will lose billions of dollars by the end of the decade due to this undercounting issue. So, it is an important task to find the proper reason and sources of undercounting in Florida. The US …

Gender Equity: The Perception Of Career Advancement In Higher Education, Whitney K. Washington

UNF Graduate Theses and Dissertations

Women have made many strides in many industries, yet a gendered leadership gap still exists. On many college and university campuses, women are the top degree earners, but they are not represented in executive leadership roles in higher education. The purpose of this quantitative study is to examine university staff perception of career advancement by investigating how independent variables—demographics, challenges and barriers, diversity management, career planning, work-life balance, and pay—are related to the dependent variable—careeradvancement. The study explores the perception of career advancement as a factor that may explain the gendered leadership gap. This study answers the following research questions: …

Spatial Equity In Accessing Critical Facilities During Hurricanes, Pooya Komeilian

UNF Graduate Theses and Dissertations

Florida encounters multiple natural disasters every year, making evacuation a critical mitigation plan when severe impacts are predicted. Evacuation is a complex procedure that involves everything from household decision-making to large-scale traffic network analysis. It also addresses logistical issues, such as transporting impacted people to shelters or medical centers. Access to shelters, gas stations, and lodgings is of utmost importance, as numerous studies and surveys have shown that some people prefer not to evacuate, even if they perceive the disaster risk to be very high.

Based on this, the present study follows two phases to address gaps in evacuation studies. …

Factors Influencing Household Travel Behavior And Trip Distances In Florida: A Rural Vs. Urban Perspective, Kadeem Lafargue

UNF Graduate Theses and Dissertations

This thesis investigates disparities in travel behaviors between rural and urban populations in the United States, with a specific focus on Florida. Leveraging data from the 2017 National Household Travel Survey (NHTS), the study examines demographic factors such as age, income, and household size, and their influence on travel patterns. By employing statistical methods including Poisson and negative binomial regression models, the research explores two key variables: the frequency of trips made per day and the average trip distance in miles. These models are particularly effective in handling overdispersion in count data, ensuring a robust analysis of travel behaviors across …

Exploring Parental Engagement In A Family Stem Program Leveraging Social Media Spaces, Valentina Bongiovanni

UNF Graduate Theses and Dissertations

The Family Take-home STEM Toolkit Program offers families the opportunity to engage in science, technology, engineering, and mathematics (STEM) learning by utilizing the informal environments of the home and program-dedicated social media groups. This initiative provides a frame for this research, as parental engagement in the context of this early childhood program is explored through the lens of the Ecologies of Parental Engagement (EPE). This theoretical model understands engagement as the mediation of space and capital (Barton et al., 2004) and guides this study to further explore parental perceptions concerning the social media space activated with the STEM Toolkit Program. …

Passperfect: A Secure One Time Password Authentication System, Charlene H. Crawshaw

UNF Graduate Theses and Dissertations

Most organizations have established strong password policies and standards to ensure the confidentiality, integrity, and availability of their data, applications, and critical systems. Even with rigorous implementations and layered approaches such as utilizing multifactor authentications, there are still flaws and vulnerabilities as they have a high dependency on the user adhering to them. In conjunction with these policies, a strong security awareness program should be implemented to educate the end user about strong password hygiene. In this work, we design and implement a secure one-time password (OTP) system, “PassPerfect”, to provide a method of enforcing a strong set of password …

Florida Queer K12 Teachers Perceptions Of School Climate Under “Don’T Say Gay”, Katherine E. Foley

UNF Graduate Theses and Dissertations

Florida's newest legislation leaves many Florida queer teachers feeling marginalized and unprotected in the classroom (Block, 2022). The “Parental Rights in Education” Bill (FL HB 1557 and FL HB 1069), infamously renamed “Don’t Say Gay”, was created ostensibly to help protect parental rights and choices in education. The new law prohibits the discussion of gender identity and sexual orientation in kindergarten through twelfth grade classrooms. “Don’t Say Gay” provides vague guidelines for queer teachers on approaching topics like sexual orientation and gender identity. Despite the evidence that queer teachers who are open and honest about their identity often find themselves …

Why Equity Follows The Law, Adam J. Macleod

Scholarly Articles

Renewed attention to equity in higher education is welcome because true equity helps us to reason together well. When administered correctly, the jurisprudence of equity models civil discourse and, therefore, can teach us how to carry out civic engagement reasonably. Equitable interpretation of the law teaches us how to understand each other charitably. And equity’s deference to law teaches us how to reason well together about our practical problems. Law is the practical reasoning that we do together. Equity serves the ends of justice by serving law, rather than undermining it. These functions of equity in adjudication point toward a …

Breach Of Faith: The Special Problem Of Osha Performance Standards, Marshall J. Breger, Arthur G. Sapper

Scholarly Articles

This Article focuses on a special problem with performance standards - that their performance criteria are often so subjective as to deny regulated persons a clear idea of what is required. It begins with a discussion of specification and performance standards in American regulatory history. It further discusses attempts by Congress and others to, therefore, require that performance criteria be “objective.” The Article then sets out a case study of how congressional attempts to require “objective” performance criteria have fared. It examines in depth whether one agency, the Occupational Safety and Health Administration (OSHA), has complied with that special requirement …

"Appropriate" Appropriations Challenges After Community Financial, Chad Squitieri

Scholarly Articles

The standard federal agency must come to Congress each year, hat in hand, and request another round of congressional funding. This annual appropriations process ensures that Congress maintains at least some influence over the vast array of rules and regulations that govern Americans' daily lives. Sure, Congress might have delegated broad authority to administrative agencies to develop national policy on Congress's behalf. But an agency reliant on annual appropriations is an agency with the financial incentive to exercise its delegated authority with an eye toward pleasing congressional appropriators. The annual appropriations process is therefore a sensible (even if insufficient) step …

Group Ownership And The Ends Of Legal Fictions, Adam J. Macleod

Scholarly Articles

The march of the progressive societies was, as we all know, from status to contract. And now? And now that forlorn old title is wont to introduce us to ever new species and new genera of persons, to vivacious controversy, to teeming life; and there are many to tell us that the line of advance is no longer from status to contract, but through contract to something that contract cannot explain, and for which our best, if an inadequate, name is the personality of the organized group.

An Examination Of Scientific And Technical Communication For Forensic Engineering And Forensic Pathology., Tori C. Reeder

Dissertations, Master's Theses and Master's Reports

Police communication sits at the unique intersection of risk communication, scientific and technical communication, and medical communication, as we see in forensic reports. In this dissertation, I examine the communicative underpinnings of forensic pathology and forensic engineering reports. I argue that there is not only an inherent link between the unpredictability of a written text and the reception of said text by both its intended and unintended audience, but also a link to the broader socio-cultural contexts. I will examine an atypical forensic pathology report (autopsy report) of George Floyd, a more standard forensic pathology report of an inmate who …

“Not Much Of A Job”: Everyday Life And Labor At Camp Au Train, Josef T. Iwanicki

Dissertations, Master's Theses and Master's Reports

In this thesis, I use data from Camp Au Train, a Civilian Conservation Corp camp in Michigan’s Hiawatha National Forest, as a case study to connect the everyday life of enrollees with dominant government narratives while including a focus on labor and the capitalist crisis of the Great Depression. Using the vantage point of work, play, study, and health, I integrate archaeological, historic, and photographic evidence to show contradictions between the enrollees’ real lived experience and the dominant perspectives of the CCC ‘authorities’ who organized their lives. I argue that to interpret these contradictions, the CCC needs to be connected …

Using A Reverse Visually Guided Reaching Task To Distinguish Between Healthy Aging And Early Alzheimer’S Disease, Brandon Woolman

Dissertations, Master's Theses and Master's Reports

Changes in motor behavior may function as a proxy for cognitive decline. While Alzheimer's disease (AD) is associated with impairments in learning and memory, recent studies suggest that subtle changes in motor task performance may reflect early cognitive changes. For example, the visuomotor rotation task that manipulates visual feedback about hand position during reaching movements, can be used to examine cognitive changes in aging populations. The current study used the reverse visually guided reaching task (rVGR) which rotates visual feedback of participant’s hand position 180⁰ relative to the actual hand position. We sought to expand on previous literature by recruiting …

Chemical Synthesis Of Sensitive Dna, Komal Chillar

Dissertations, Master's Theses and Master's Reports

Over the past decades, researchers have tried various chemical methods to synthesize modified oligodeoxynucleotides (ODNs, i.e. short segments of DNAs). Traditional ODN synthesis methods require strong basic, and nucleophilic conditions for the deprotection and cleavage of the ODN from the solid support. However, the sensitive ODNs containing labile functionalities are vulnerable to such harsh conditions. Sensitive ODNs have a wide range of applications in research and pharmaceuticals. To synthesize sensitive ODNs, researchers devised different strategies but no practical methods have been developed. To overcome these challenges, we developed alkyl Dim alkyl Dmoc technology. This innovative technology uses weakly basic and …

An Elasto-Plastic Constitutive Model With Phase-Field Fracture For Additively Manufactured Metallic Materials, Nolan Ruble

Dissertations, Master's Theses and Master's Reports

The advent of additive manufacturing (AM), commonly known as 3D printing, has revolutionized the production of metallic components across various industries. This technology, which builds objects layer by layer, has shifted paradigms in manufacturing, allowing for unprecedented design freedom, material efficiency, and rapid prototyping. Metal additive manufacturing, in particular, has shown remarkable promise due to its ability to produce complex geometries that are difficult or impossible to achieve with traditional subtractive methods. In addition, additively manufactured (AM) materials are gaining popularity in thanks to their often superior and controllable properties in comparison to their wrought counterparts. In the present work, …

Performance Characterization And Optimization Of A Point-Cloud-Based Path Planner In Off-Road Terrains, Casey D. Majhor

Dissertations, Master's Theses and Master's Reports

In this dissertation, I present a multifaceted study on the generation of artificial terrains using a multifractal method, and their use in autonomous ground vehicle (AGV) planning and navigation performance characterization in high-fidelity simulations, and automated parameter optimization.

My first contribution is a multifractal artificial terrain generation method leveraging the 3D Weierstrass-Mandelbrot function to control terrain roughness. We generate 60 unique off-road terrains while varying the fractal dimension and test the impact on vehicle traversal difficulty. Results show that increasing the fractal dimension decreases low-roughness areas, increases semi-rough and high-roughness areas, and decreases vehicle success rates while increasing vertical accelerations, …

Modeling Pulsatile Flows Using Truly Incompressible Finite Volume Lattice Boltzmann Model, Akshay S. Dongre

Dissertations, Master's Theses and Master's Reports

The present study addresses the compressibility error inherent in the standard Lattice Boltzmann Method (LBM) and LBM’s restriction to uniform Cartesian meshes. To mitigate the compressibility error, an incompressible LBM (iLBM) model has been incorporated into the finite volume framework using a cell-centered finite volume approach, leveraging the simplicity of the LBM algorithm for irregularly shaped flow domains with unstructured meshes. Monotonic Upstream-centered Scheme for Conservation Laws (MUSCL) and linear reconstruction (LR) schemes have been used to compute convective fluxes across the cell interfaces with boundary conditions implemented using the second-order accurate Non-Equilibrium Extrapolation (NEE) method.

The finite volume iLBM …

Sustainable Materials For Environment − Multifunctional Material Made From Dead Leaves And Nanostructured Materials For Antibiotic Degradation, Siyuan Fang

Dissertations, Master's Theses and Master's Reports

As environmental pollution from industrial processes and human activities continues to rise, finding efficient approaches to recycle waste materials and degrade persistent contaminants becomes increasingly critical. Dead leaves, an abundant but underutilized biomass, present an opportunity for creating value-added materials if their biocomponents can be preserved and transformed. Simultaneously, antibiotics such as tetracycline are widely found in water bodies but pose serious ecological and health risks, necessitating effective degradation methods. This dissertation addresses these challenges by leveraging natural and nanostructured materials to develop multifunctional products and advanced photocatalytic processes.

Chapter 3 of this dissertation addresses the challenge of converting waste …

Phase Field Modeling Of Fracture And Phase Separation Using Numerical Methods And Machine Learning, Revanth Mattey

Dissertations, Master's Theses and Master's Reports

Phase field modeling is a crucial tool in scientific and engineering disciplines due to its ability to simulate complex phenomena like phase transitions, interface dynamics, and pattern formation. It plays a vital role in understanding material behavior during processes such as solidification, phase separation, and fracture mechanics. Particularly in fracture mechanics, phase field modeling can be utilized to predict the crack path in complex materials. Understanding the failure behavior is vital for applications of any material. The specific contributions to the field of phase field fracture mechanics, are, Firstly, we propose a novel phase field fracture model to simulate the …

Investigating Microphysical Variability And Entrainment In Clouds Using Airborne Digital Holography, Machine Learning, And Large Eddy Simulations, Nithin Allwayin

Dissertations, Master's Theses and Master's Reports

Advancing our understanding of cloud microphysics—the processes governing cloud particles' formation, growth, and interactions—is essential for accurate weather and climate modeling. In this work, we investigate how droplet size distributions vary in a cloud and explore how microphysical properties such as droplet size and number concentration respond to entrainment and mixing.

In the first part of the work, a novel algorithm is developed combining hypothesis testing with density-based clustering to identify characteristic cloud droplet size distribution types in marine stratocumulus clouds. Applied to data from the airborne Holographic Detector for Clouds (HOLODEC), the algorithm successfully identifies a relatively small set …

Synthesis Of Long Oligodeoxynucleotides, Yipeng Yin

Dissertations, Master's Theses and Master's Reports

Synthetic long oligodeoxynucleotides (ODNs) have found wide applications in diverse fields such as chemical biology, synthetic biology, and genes and genomes synthesis. Those applications leading to a significant demand for their production. However, traditional methods for purifying synthetic ODNs present notable drawbacks, particularly their inability to purify long ODNs, rendering long ODN synthesis challenging. To address these issues, chemical synthesis techniques for long ODNs coupled with non-chromatographic purification methods have been developed. This technology makes the purification of long synthetic ODNs feasible and offers a viable pathway for producing genes and genomes with extensive repeats or stable secondary structures, which …