Digital Commons Network^™

The Effects Of Video Game Use On Spatial Ability In A Landmark Memory Task, Brendan T. Jacobs, Christina A. Thrasher, Lauren L. Harburger

Modern Psychological Studies

The present study sought to determine whether playing video games more often improves spatial ability on the landmark memory task. The researchers hypothesized that participants who play video games more often would perform better on the task than those who play video games less often. One hundred seventy-two participants (80 men and 92 women) between the ages of 18 and 26 filled out a questionnaire which asked about video gaming habits prior to a landmark memory task. The landmark memory task consisted of 10-second videos that showed 180-degree views of various locations. At the completion of each video, an image …

Early Identification Of Autism Spectrum Disorder In Childcare Settings: A Literature Review, Maneli Nourzad

Modern Psychological Studies

Timely intervention is key in the development of children with Autism Spectrum Disorder (ASD) and early childhood settings present an opportune environment for early diagnosis, particularly in Canada where the identification of ASD in children below the age of four can be further expanded. This review first summarizes the potential benefits and barriers to early identification of ASD in children. There is robust evidence that early detection can result in improved biological and behavioral outcomes in later stages of life despite the subtle and at times elusive signs of ASD in young children. We then focus on the role early …

Heteroleptic Coumarin-Based Silver(I) Complexes: Possible New Antimicrobial Agents, Erika Mooney, Brendan Twamley, Gordon Cooke, Emma Caraher, Matthias Tacke, Fintan Kelleher, Bernadette S. Creaven

Articles

Heteroleptic coumarin-based silver(I) complexes with improved solubility profiles were synthesised using either triphenylphosphine or an N-heterocyclic carbene as adduct ligands, and were fully characterised using IR and NMR spectroscopy, elemental analysis, and, where possible, X-ray crystallography. The triphenylphosphine adducts formed well-resolved structures, where the oxyacetate ligands asymmetrically chelated the silver(I) ion in a bidentate chelating mode, and the silver(I) ion was also bound to two triphenylphosphine ligands. The solubility profile and photostability of the adducts were considerably improved compared to those of previously isolated simple coumarin silver(I) complexes. Analysis of the coumarin N-heterocyclic carbene(NHC) silver(I) adduct indicated that it likely …

Population Viability Of Egyptian Tortoises: Analyzing Demographics Sensitivities And Extinction Risk In North Sinai, Basem Ahmed Rabia Motwaly

Graduate Theses/Dissertations

This study investigated the population viability of the critically endangered Egyptian Tortoise (Testudo kleinmanni) across five populations in North Sinai, Egypt. The research aimed to assess demographic sensitivities, extinction risks, and the influence of environmental variables to guide conservation strategies. Using multistate mark-recapture models within a Bayesian framework, survival, transition, and recapture probabilities were estimated across life stages, integrating site-specific environmental data such as the Normalized Difference Vegetation Index (NDVI). The analysis revealed stark contrasts between populations, with three sites demonstrating high extinction risk due to lower juvenile survival and limited recruitment. In contrast, two populations exhibited demographic …

Scent Trailing In Neonate Agkistrodon Piscivorus When Exposed To Conspecific And Heterospecific Chemical Cues, Samantha R. Grove

Graduate Theses/Dissertations

Chemosensation is central to snake ecology, playing an essential role in predator recognition, foraging success, and communication with conspecifics. In areas with cold winters, neonatal snakes often trail chemical cues from older individuals to locate communal hibernacula essential for winter survival. Juvenile Northern Cottonmouths (Agkistrodon piscivorus) form social bonds with littermates and have been shown to trail chemical cues of conspecifics in the fall. However, the effect of relatedness on trailing phenomena has not been tested. Using y-maze experiments I evaluated trailing behavior of 32 captive-born neonate Northern Cottonmouths (Agkistrodon piscivorus) to determine if (1) subjects prefer to trail siblings …

Epigenetic Mechanism Of Ebp1 In Nlrp-Dependent Development, Summer Reign Moore

Graduate Theses/Dissertations

ErbB3-binding protein 1 (EBP1) helps regulate gene expression through various epigenetic modifications and is crucial for embryotic development. NLRP2 and NLRP7 are more commonly known for their roles in the immune system, however, recent research has implicated NLRP2 and 7 as critical factors in embryonic development. EPB1, NLRP2, and NLRP7 dysfunction is a known cause of recurrent miscarriages and other developmental diseases, including infertility. NLRP2 and NLRP7 are also known to affect the levels of DNA methylation, despite that they are located exclusively in the cytoplasm. However, EBP1 can be located in the nucleus and cytoplasm, and is known to …

Effect Of P2y2 Receptors On Leukocyte Behavior Under Acute Inflammation In Transgenic Male Mice In Vivo, Corynn D. Knight

Graduate Theses/Dissertations

P2Y₂ receptors, G-protein coupled receptors and transmembrane proteins, are present on most cells in the body and hold a wide variety of roles. Previous research indicates that under resting conditions, P2Y₂ receptors suppress the movement of leukocytes but it is unknown how inflammation will alter this in the body. The objective of this project was to determine the effect of P2Y₂ receptors on leukocyte behavior in vivo under acute inflammation using Intravenous Microscopy (IVM) in post-capillary venules of the cremaster skeletal muscle. Lipopolysaccharide was injected into the scrotum of transgenic male mice to cause localized acute inflammation. …

Enhancing Microwave Disinfection: Impact Of Sodium Chloride On Microbial Inactivation, Saleh A. Alfawaz, Ibrahim Nasser I. Alquaydheb, Amirreza Ghadimi Avval, Sara Ghayouraneh, Samir M. El-Ghazaly, Jianhong Zhou

Electrical Engineering and Computer Science Faculty Publications and Presentations

This study explores the role of sodium chloride (NaCl) in enhancing the efficiency of microbial inactivation using microwave energy with two distinct methods: temperature-controlled treatment and predefined cycle. The primary objective is to maintain a stable temperature within the biological samples during treatment. Detailed descriptions of the treatment system’s design and the function of each element are provided. Simulations are conducted to illustrate the heating behavior of liquids with and without NaCl, revealing significant differences in temperature profiles between the two media. The experimental design and the objective behind each iteration are discussed. The experimental design includes three different power …

Children's Moments Of "Becoming" In Classrooms: Spatial Production And Multiliteracy Practices, Seongryeong Yu

Teaching & Learning Faculty Publications

While immigrant children’s identity negotiation and their sense of belonging are increasingly highlighted, existing literature remains largely focused on language abilities and identity struggles, often emphasizing rigid definitions of “identity” grounded in blood, language, and culture. Drawing on findings from my dissertation, this comparative ethnographic case study examines the fluidity of identity through literacy practices that help children construct meaning and foster belonging. By analyzing how 10-year-old students’ literacy practices interact with physical and social environments at school, I discuss shared expressions of emotions, power dynamics, the role of language, and variations in the use of cultural materials. These moments …

Development Of Radiochemistry Of 52mn For Pet Imaging Applications, James Mokaya Omweri

All ETDs from UAB

No abstract provided.

Integrating Remote Sensing With Ground-Based Observations To Quantify The Effects Of An Extreme Freeze Event On Black Mangroves (Avicennia Germinans) At The Landscape Scale, Melinda Martinez, Michael J. Osland, James B. Grace, Nicholas M. Enwright, Camille L. Stagg, Camille L. Stagg, Simen Kaalstad, Gordon H. Anderson, Elena A. Flores, Alejandro Fierro-Cabo

School of Earth, Environmental, & Marine Sciences Faculty Publications

Climate change is altering the frequency and intensity of extreme weather events. Quantifying ecosystem responses to extreme events at the landscape scale is critical for understanding and responding to climate-driven change but is constrained by limited data availability. Here, we integrated remote sensing with ground-based observations to quantify landscape-scale vegetation damage from an extreme climatic event. We used ground- and satellite-based black mangrove (Avicennia germinans) leaf damage data from the northern Gulf of Mexico (USA and Mexico) to examine the effects of an extreme freeze in a region where black mangroves are expanding their range. The February 2021 …

Students Engaging In Public Health Research: An Opportunity To Enhance Education, M. Courtney Hughes, Sadia Afrin

Faculty Articles, Papers, and Other Scholarship

Society is on the heels of one of the largest public health crisis the world has experienced in over a century, the COVID-19 pandemic. Developing the next generation of adept public health researchers is paramount to protecting the world against future health threats and addressing legacy public health challenges. This article explores the transformative influence of research experience on education, presenting three major points: (1) students engaging in public health research is timely, (2) students can develop a variety of critical thinking skills and data-driven decision-making capabilities that prepare them for future careers, and (3) faculty and universities benefit from …

A Bayesian Inversion For Emissions And Export Productivity Across The End-Cretaceous Boundary, Alexander A. Cox

Dartmouth College Master’s Theses

The end-Cretaceous mass extinction was marked by both the Chicxulub impact and the ongoing emplacement of the Deccan Traps flood basalt province. Both of these events perturbed the environment by the emission of climate-active volatiles, primarily CO2 and SO2. To understand the mechanism of extinction, we must disentangle the timing, duration, and intensity of volcanic and meteoritic environmental forcings. In this thesis, we used a parallel Markov chain Monte Carlo approach to invert for the aforementioned volatile emissions, export productivity, and remineralization from 67 to 65 million years ago using the LOSCAR (Long-term Ocean-atmosphere-Sediment CArbon cycle Reservoir) model. The parallel …

The Regenarrative: How To Change The Story In Order To Change The Future, S. Rose Bigheart O'Leary

Dartmouth College Master’s Theses

Abstract

In the era of Climate Change, many are concerned that the end of the Anthropocene, or the end of the era of human life on Earth, is upon us. Western European colonialism and its subsequent systems (settler-colonialism, colonial-capitalism, and globalization - sometimes termed “neocolonialism”) have all been implicated in contributing to unsustainable behaviors linked to accelerating climate change. In searching for possible solutions, some have called for listening to Indigenous Peoples, citing ethics of sustainability found among many Indigenous cultures. However, the cultural products of settler-colonialism are still dominant in ways that do not allow for Indigenous worldviews to …

Advancements In Sarcoma- And Nerve-Specific Fluorescence Imaging For Surgical Guidance, Kendra A. Hebert

Dartmouth College Master’s Theses

Fluorescence guided surgery (FGS) is an evolving field that aims to improve patient outcomes by using fluorophores to identify important tissues during surgery, such as tumors and nerves. In this thesis work, we explored different methods of identifying nerve and tumor tissues for FGS and a novel fluorescence-based method to determine the depths of these structures.

Researchers have explored using fluorescence guided surgery for surgical resection of cancerous tissues, including recent work by our group focusing on identifying soft tissue sarcomas with ABY-029, an epidermal growth factor receptor targeting probe. However, our preclinical and clinical work shows no single reporter …

Building Smart Textile Sensors From Bottom-Up: Chemically Precise Self Assembled Materials On Textiles As A Modular Platform For Electroanalysis, Lori-Ann Williams

Dartmouth College Master’s Theses

In this present work, we explore the metallization of textiles and sutures for the development of a wearable portable modular platform technology for non-invasive wound healing monitoring. Currently technology for the metallization of nonconductive materials have been mainly on a 2D surfaces which restricts the bulk metallization of textile surfaces which require specialized equipment and operators which are costly, energy ineffective, and prevents miniaturization. Metallization of nonconductive fabrics are achieved through a conventional electroless deposition of copper nanoparticle species on 3D surfaces to create electrodes. These conductive textiles and sutures were characterized by pXRD, ATR-IR, SEM-EDS, and XPS and were …

Asynchronous Movement Patterns Between Breeding And Stopover Locations In A Long-Distance Migratory Songbird, Theodore Zenzal, Andrea Contina, Hannah Vander Zanden, Leanne Kuwahara, Daniel Allen, Kristen Covino

Faculty Publications

The species-specific migratory patterns and strategies of many songbirds remain unknown or understudied, as research in animal ecology is biased toward the breeding period, with the fewest studies on the migratory period across taxa. Identifying large-scale spatiotemporal migratory patterns is challenging, as individuals within a species may vary in their migratory behavior and strategies. The Yellow Warbler (Setophaga petechia) is a Nearctic-Neotropical migrant that is relatively well studied during the breeding season, but its species-wide migratory patterns remain understudied. Our aim in studying Yellow Warbler movement ecology was to characterize temporal migration patterns during fall migration. We sought to determine …

The Role Of Altered Cell-Cell Communication Between Glia And Neurons In Alzheimer’S Disease, Tabea Marga Soelter

All ETDs from UAB

Alzheimer’s disease is the most prevalent neurodegenerative disease and is characterized by progressive memory loss and cognitive decline, affecting behavior, speech, and motor abilities. The neuropathology includes the formation of extracellular amyloid-β plaques and intracellular neurofibrillary tangles of phosphorylated tau. Additionally, neurons become functionally impaired before degenerating and dying. While neuronal loss is a disease hallmark, glia maintain neuronal health and homeostasis through cell-cell communication with neurons. Cellular crosstalk is mediated through the release of chemical intermediates (i.e., ligands), which are taken up by cell surface membrane receptors. Previous studies have shown dysregulation of global cell-cell communication patterns and communication …

Optical Absorption Of Defects In Aluminum Nitride, Mackenzie Siford

All ETDs from UAB

Aluminum nitride (AlN) is an ultrawide bandgap semiconductor material known for its applications in high power microelectronic and optoelectronic devices due to its high thermal conductivity and high electrical resistivity. Point defects are known to hinder the material’s properties and are therefore a subject of interest in semiconductor materials research. The samples used in this work were grown by physical vapor transport (PVT) at Hexatech and they exhibit amber and clear coloration as well as a nonuniformity of charge, which was investigated. Experiments were carried out by electron paramagnetic resonance (EPR) and photo-EPR spectroscopy in order to detect the defect …

Exploring International Educators' Learning About Local And Global Social Justice In A Virtual Community Of Practice, Bima Sapkota, Xuwei Luo, Muna Sapkota, Murat Akarsu, Emmanuel Deogratias, Daphne Fauber, Rose Mbewe, Fidelis Mumba, Ram Krishna Panthi, Jill Newton

School of Mathematical & Statistical Sciences Faculty Publications

In this chapter, the authors report themes that emerged when a cross-cultural team of researchers involved in a virtual international community of practice (Global Social Justice in Education-GSJE) investigated reflections on activities focused on social justice in local and global contexts. The findings suggested that the activities elicited GSJE community members' understandings of the complexities of social justice associated with naming practices, privilege, and the arts within their own and across contexts. The authors discuss implications of the activities to advance diverse educators' understanding of social justice in global and local contexts. They also unpack the opportunities and challenges that …

Growing Need For A Standardized Response To Radiopharmaceutical Extravasations, Michael Richard Drelich

All ETDs from UAB

Extravasations are medical occurrences where an injected or infused pharmaceutical is unintentionally deposited into the soft tissue near the injection site, rather than into the bloodstream. With radiopharmaceuticals, extravasations can result in potentially large radiation doses to skin and tissue. The current rate of extravasations in clinical settings is estimated to be between 3-23%. In the interest of patient safety, a clearer understanding of the dosimetry and differences in extravasation scenarios to simplify dose estimation is needed. Similarly, the NRC is considering modifying regulations to include extravasations as reportable medical events rather than to continue considering them as patient interventions. …

Halfway Out: The Lived Experiences Of Black Closeted Gay Male Educators In Predominately Black Schools, Gianna C. Faustin-Mcleese

Graduate Student Dissertations, Theses, Capstones, and Portfolios

This narrative inquiry aimed to delve into the lived experiences of Black closeted gay male educators in predominantly Black public schools. While existing research has extensively explored the experiences of Black gay males, there is a notable gap in understanding the lived experiences of Black closeted gay male educators. Specifically, little research has examined how these educators' experiences unfold within the context of predominately Black public schools and how these experiences shape their professional identity as they navigate their communities. The investigation centered around one central research question and one auxiliary question: Firstly, what are the lived experiences of closeted …

Transformative Learning Outcomes: Shifting The Learning Outcome Conversation From Assessment To Design, Mat D. Duerden, Jamin C. Rowan

Faculty Publications

What if the focus of learning outcomes shifted from telling students what they will know at the end of a course to who they will become? Learning outcomes have drifted away from informing curriculum design to providing parameters for external assessment. This article reviews this shift along with a proposal to reimagine learning outcomes as transformative learning outcomes. It discusses previous work on transformative learning outcomes and proposes a new conceptual definition: learning outcomes that articulate habits of mind or ways of being that students will develop because of a learning experience or sequence of learning experiences. Such learning outcomes …

Nanotube Spectral Fingerprinting And Machine Learning For Optimized Bioimaging/Sensing Applications, Aceer Nadeem

Open Access Dissertations

This thesis presents a multifaceted exploration of the optimization and application of single-walled carbon nanotubes (SWCNTs) in biomedical contexts, with a specific focus on enhancing their stability, functionality, and use as optical biosensors. The research spans several key areas, including the development of innovative techniques that couple machine learning with spectral fingerprinting for advanced diagnostics, the investigation of SWCNT chirality and its implications for cellular interactions, and the optimization of lyophilization processes to improve long-term stability and reproducibility.

The first section of the thesis delves into the fundamental properties of SWCNTs, emphasizing their unique electronic and optical characteristics. These properties, …

Treading Carefully In The Deep Ocean: Insights Into The Effects Of Artificial Light And Sound From Robotic Platforms On Pelagic Animal Surveys Using Active Acoustics And Low-Light Imaging Techniques, Rendhy Moreno Sapiie

Open Access Dissertations

Science and technology are coupled disciplines. Breakthroughs in ocean science are often pertinent to the ability to observe physical, chemical, and biological processes at the right temporal and spatial scales, which typically involves the use of robots. Large, powerful, and extremely capable, the scientific work-class remotely operated vehicle (ROV) is the golden standard when observing fine temporal scale intricate processes in the full ocean stratum and has unraveled important discoveries in deep-sea biology and ecology. Sound, light, and hydrodynamic forces produced from these vehicles are sources of disturbances that may impact quantitative observations in the twilight zone, an environment absent …

Innovative Bioink Formulation For 3d Bioprinting Of Tissue-Engineered Intervertebral Disc Implants, Sophia Boiani

Open Access Master's Theses

Intervertebral disc (IVD) degeneration is a significant contributor to back pain and disability globally, necessitating advancements in treatment options. This thesis presents the development and characterization of a novel bioink to be used for generating 3D bioprinted tissue-engineered constructs of the nucleus pulposus (NP) region of the IVD. The bioink, a composite of methylcellulose (MC, 7 wt%), polyethylene glycol diacrylate (PEGDA, 15 wt%), and Lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, 0.1 wt%), is optimized for enhanced mechanical properties and cellular integration. Polylactic-co-glycolic acid (PLGA) nanoparticles were also incorporated in the hydrogel to potentially delivery growth factors in the future, which will support cell …

Cross-Laminated Timber For Sustainable Construction - Long-Term Performance And Environmental Impacts, Arthiha Tharmrasan

Open Access Master's Theses

As concerns about climate change and its extensive impacts continue to grow, the construction industry has become focus of attention due to its substantial role in contributing to carbon dioxide emissions and resource depletion. This research thesis delves into the potential of timber structures, particularly cross-laminated timber (CLT), to offer sustainable alternatives to traditional construction materials. The study is structured into two main parts: an examination of the long-term performance of CLT and an evaluation of its environmental impacts through life cycle assessment (LCA).

The initial section of the study focuses on the durability and mechanical integrity of CLT structures, …

Telechelic Polymers As High-Performance Rheological Modifiers In Biomimetic Polymer-Linked Emulsions, Daniel P. Keane

Open Access Dissertations

Due to the complexity of biological tissue and the numerous challenges associated with research into biological particle transport, it is of interest to scientists to develop a synthetic mimic that can replicate key attributes of multicellular tissue. The work presented in this dissertation details the design, characterization, and application of a synthetic material for use as a phantom material in research into biological particle transport. Furthermore, the designed materials introduce exciting polymer physics problems and present broad potential uses as rheological modifiers for colloidal systems and 3D printing inks. The polymer-linked emulsions which form the basis of this work are …

Pathophysiology Of Pain And Mechanisms Of Neuromodulation: A Narrative Review (A Neuron Project)., Marcin Karcz, Alaa Abd-Elsayed, Krishnan Chakravarthy, Mansoor M Aman, Natalie Strand, Mark N Malinowski, Usman Latif, David Dickerson, Tolga Suvar, Timothy Lubenow, Evan Peskin, Ryan D'Souza, Eric Cornidez, Andrew Dudas, Christopher Lam, Michael Farrell Ii, Geum Yeon Sim, Mohamad Sebai, Rosa Garcia, Lucas Bracero, Yussr Ibrahim, Syed Jafar Mahmood, Marco Lawandy, Daniel Jimenez, Leili Shahgholi, Kamil Sochacki, Mohamed Ehab Ramadan, Vinicius Tieppo Francio, Dawood Sayed, Timothy Deer

Neuroscience Articles

Pain serves as a vital innate defense mechanism that can significantly impact an individual's quality of life. Understanding the physiological effects of pain well plays an important role in developing novel pain treatments. Nociceptor neurons play a key role in pain and inflammation. Interactions between nociceptors and the immune system occur both at the site of injury and within the central nervous system. Modulating chemical mediators and nociceptor activity offers promising new approaches to pain management. Essentially, the sensory nervous system is essential for modulating the body's protective response, making it critical to understand these interactions to discover new pain …

Abductive Empiricism: The Significance Of Substance In Andy Weir's Project Hail Mary, Jordan Maloney

EWU Masters Thesis Collection

In a world of matter and meaning, philosophical debates revolve around metaphysical connections among entities. Alfred North Whitehead and Charles Peirce see interconnectedness in a continuous process of becoming, Karen Barad explores the constant creation of entities through intra-action, and Erwin Schrӧdinger quantifies the connection between the quantum and the macroscopic world. To add on to this discourse, I argue that ontological connections can be formed between any two static entities based on their shared quantitative data. It is pertinent to note that while this research draws inspiration from Whitehead, Peirce, and Barad, my approach differs significantly. In Whitehead and …