Digital Commons Network^™

An In Vitro Experimental System Of Muscle Formation, Sheila Navarrete, Allison Boss-Kennedy, Jie Chen

Parkland Science Scholars

Overview: Muscle Regeneration

Muscle formation occurs at two points in time:

• Embryonic development
• Adult Muscle regeneration
• Muscle is one of few tissues capable of robust regeneration
• Due to the presence of quiescent stem cells known as satellite cells
• Muscle regeneration is an intricate process with multiple transitions that must take place
• These transitions can be regulated by many factors

The Multifunctional Catalytic Hemoglobin Fromamphitrite Ornata: Protocols On Isolation, Taxonomic Identification, Protein Extraction, Purification, And Characterization, Anna L. Husted, Lauren A. Presnar, R. Kevin Blackburn, Joseph L. Staton, Stephen A. Borgiani, Edward L. D'Antonio

Natural Sciences Faculty Publications

The multifunctional catalytic hemoglobin from the terebellid polychaete Amphitrite ornata, also named dehaloperoxidase (AoDHP), utilizes the typical oxygen transport function in addition to four observed activities involved in substrate oxidation. The multifunctional ability of AoDHP is presently a rare observation, and there exists a limitation for how novel dehaloperoxidases can be identified from macrobenthic infauna. In order to discover more infaunal DHP-bearing candidates, we have devised a facilitated method for an accurate taxonomic identification that places visual and molecular taxonomic approaches in parallel. Traditional visual taxonomic species identification by the non-specialist, at least for A. ornata or even for other …

Answering Big Questions With Big Data: Using Analytics Across The Research Ecosystem, Ann Beynon

Research Analytics Summit 2024

The research landscape continues to shift and evolve. With challenges around research integrity and security growing, research leaders must rely on the highest quality data to make confident decisions. Universities and funders need to understand the societal impact of research investments in addition to the scholarly impact. Has research helped to advance the UN Sustainable Development Goals? What are the emerging research areas that will lead to commercial innovations and sustainability advancements? We will discuss how quantitative data from Web of Science and InCites can help research stakeholders understand these big questions and inform their strategic research decisions.

Collabnext -A Person-Focused Open Knowledge Graph For Collaborations With Emerging Researchers, Lew Lefton

Research Analytics Summit 2024

CollabNext is being developed as part of the NSF ProtoOKN (Prototype Open Knowledge Network) effort. This project originated as a partnership between Georgia Tech and the Atlanta University Center, and is now being developed jointly by Fisk University, Georgia Tech, Morehouse College, Texas Southern University, and University at Buffalo with support from the NSF TIP Directorate.

Our goal is to develop a knowledge graph based on people, organizations, and research topics. We are adopting an intentional design approach which initially prioritizes HBCUs and emerging researchers in a deliberate effort to counterbalance the Matthew effect, a naturally accumulated advantage of well-resourced …

Gender (Discrimination) Trouble, Katharine K. Baker

South Carolina Law Review

No abstract provided.

The Semiotics Of Smell: Gender, Materiality, And The Language Of Fragrances, Kathryn Copeland

Theses and Dissertations--Linguistics

Fragrances have long been used in a variety of cultures to communicate or articulate perceptions of different types of people or personae (Classen, Howes, & Synnott; 1994); however, the meanings “articulated” by fragrances have rarely been studied through the analytical frameworks of indexicality, enregisterment, and materiality (Eckert, 2008; Johnstone, 2016; Miller, 2005; Silverstein, 2003).

To do this, I first conducted a quantitative corpus analysis of user-generated reviews of popular perfumes on the fragrance database Fragrantica to identify differences in how reviewers of “men’s” fragrances and “women’s” fragrances describe their experience with the fragrances, and what these patterns indicate about how …

Common Questions And Misconceptions About Caffeine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Daniel E. Newmire, Jeffrey R. Stout, Brandi Antonio, Maureen Gibbons, Lonnie M. Lowery, Joseph Harper, Darryn Willoughby, Cassandra Evans, Dawn Anderson, Erica Goldstein, Jose Rojas, Matías Monsalves-Álvarez, Scott C. Forbes, Jose Gomez Lopez, Tim Ziegenfuss, Blake D. Moulding, Darren Candow, Michael Sagner, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak

Faculty Publications

Caffeine is a popular ergogenic aid that has a plethora of evidence highlighting its positive effects. A Google Scholar search using the keywords “caffeine” and “exercise” yields over 200,000 results, emphasizing the extensive research on this topic. However, despite the vast amount of available data, it is intriguing that uncertainties persist regarding the effectiveness and safety of caffeine. These include but are not limited to: 1. Does caffeine dehydrate you at rest? 2. Does caffeine dehydrate you during exercise? 3. Does caffeine promote the loss of body fat? 4. Does habitual caffeine consumption influence the performance response to acute caffeine …

Ductus Exemplo: A Model Municipal Executive Order On Food Waste Reduction, Linda Breggin, Darby Hoover, Jessica Sugarman

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Managing Hazardous Waste Pharmaceuticals In Healthcare: A Perplexing Prescription, Garrison Rosser

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Speaking For The States: A Response To The Proposal Of Subnational Forest Federalization, Joseph White

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

The Great Horned Owls Of Brandywine Park: Field Observations Of Urban Nesting And Predation On Bats, Holly Kirkland, Joseph Francis

Delaware Ornithologist

No abstract provided.

The Clean Water Act Section 401 Water Quality Certification Improvement Rule And Why It Deserves Chevron Deference, Joseph Retzer

Saint Louis University Law Journal

This Article reviews the history of CWA Section 401 and finds that it supports affording EPA’s newest interpretive rule Chevron deference. The CWA Section 401 Water Quality Certification Improvement Rule serves as an important case study of the doctrine which faces mounting criticisms and two cases challenging its legality in the Supreme Court at the time of this publication. Although its application delegates lawmaking authority to unelected officials who change policies with the tides of each election, this delegation has been necessary in many areas of the law due to Congress’s failure to act in recent years. Instead of simply …

A Single Thought Can Be A Portal: An Interview With Lidia Yuknavitch, Lidia Yuknavitch, Pamela Huber, Jenny Rowe

CutBank

No abstract provided.

Annual Report Of The Officers And Committees Of The Town Of Brookline, New Hampshire For Year Ending December 31, 2023, With Reports Of The School Districts For Year Ending June 30, 2023., Brookline Town Representatives

Brookline, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Town Of Richmond, New Hampshire 2023 Annual Report., Richmond Town Representatives

Richmond, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

A Binary Integer Linear Programming Model For Optimizing Underground Stope Layout, Theophilus Mensah

Masters Theses

"Underground mine planning engineers face significant challenges when determining what geometry provides the most profitable and safe stope for extraction. Several techniques and optimization algorithms have been developed in recent years, but most fail to find optimal solutions because they are heuristic or LP-based without efficient geometric constraints. This thesis work proposes a two-dimensional binary linear programming (BILP) model for determining the optimal combination of blocks in a stope that maximizes the economic value of the layout of stopes for a sublevel deposit. The work draws from Queyranne and Wolsey’s (2017 & 2018) formulations of tight constraints for bounded up/down …

Cutbank 100

CutBank

No abstract provided.

Terra Et Intus, Mark Freeman

Master's Theses or Doctor of Nursing Practice

I use nature as my escape from the daily grind. I seek out wilderness to recharge my creative batteries. Just as the forest has unseen and unappreciated levels of life, so does the entire planet. When I am trapped in the daily business of life and long for an escape to nature, I have found that I can locate that beauty almost anywhere. When evaluating the structure and design of an organism on a microscopic level, especially through electron microscopy, there exist amazing and untold levels of beauty that humanity takes for granted every day. All life forms provide some …

Case Report: Psychotherapy For Enhancing Psychological Adjustment To Dysphoric Milk Ejection Reflex, Reem Deif

Faculty Journal Articles

Given its endless benefits, breastfeeding is widely acknowledged as the optimal choice for both maternal and infant health. Nevertheless, breastfeeding mothers often encounter various challenges that may hinder their ability to fully embrace this experience. This report delves into a compelling case of Dysphoric Milk Ejection Reflex (D-MER), a largely underexamined mental health issue among lactating mothers. D-MER is characterized by intense aversion right before milk let down, which can significantly impede a mother’s willingness to breastfeed. The primary aim of this case report is to provide a comprehensive psychological understanding of D-MER, emphasizing aspects of attachment, the transition into …

Metabolomic Profiling Reveals Altered Phenylalanine Metabolism In Parkinson’S Disease In An Egyptian Cohort, Nourhan Shebl, Shaimaa El-Jaafary, Ayman A. Saeed, Passent Elkafrawy, Amr El-Sayed, Samir Shamma, Rasha Elnemr, Jaidaa Mekky, Lobna A. Mohamed, Omar Kittaneh, Hassan El-Fawal, Mie Rizig, Mohamed Salama

Faculty Journal Articles

Introduction: Parkinson’s disease (PD) is the most common motor neurodegenerative disease worldwide. Given the complexity of PD etiology and the different metabolic derangements correlated to the disease, metabolomics profiling of patients is a helpful tool to identify patho-mechanistic pathways for the disease development. Dopamine metabolism has been the target of several previous studies, of which some have reported lower phenylalanine and tyrosine levels in PD patients compared to controls. Methods: In this study, we have collected plasma from 27 PD patients, 18 reference controls, and 8 high-risk controls to perform a metabolomic study using liquid chromatography-electrospray ionization–tandem mass spectrometry (LC-ESI-MS/MS). …

The Ordinariness Of Ethics And The Extraordinariness Of Revolution: Ethical Selves And The Egyptian January Revolution At Home And School, Ramy Aly

Faculty Journal Articles

In this article I present experiences of Egyptians too young to have taken part in the street protests and movement of the 2011 revolution. Today in their early twenties, they narrate their experiences during the early months of the uprising. None claimed to be revolutionaries then or now, but the revolution seems to animate them in complex and long-lasting ways. The January revolution failed to bring about change at the level of state power. Yet more is at stake than the political endgame. I turn my attention to how people narrate the revolution as a process of ethical reflection and …

Intentional Parenthood, Contingent Fetal Personhood, And The Right To Reproductive Self-Determination, Laura D. Hermer

Faculty Scholarship

This Article argues that intent should govern legal parenthood, regardless of the method of conception, the person’s biological or genetic relationship to the resulting embryo/fetus, or the person’s gender. This proposition is not new. This Article adds to scholarly discourse by extending the concept: Intent should not just determine parenthood, but also fetal rights. When a pregnant person establishes their procreational intent (or lack thereof) prior to birth, then both the existence (or lack thereof) of legal protections for the embryo/fetus and the gestator’s rights and duties (or lack thereof) should flow from this intent. Non-gestating gamete contributors would do …

Bending Mechanics Of Bio-Mimetic Stiff Scale-Covered Plate, Pranta Rahman Sarkar

Graduate Thesis and Dissertation 2023-2024

Biomimetic scale-covered systems offer immense potential and applications, particularly in soft robotics, protective armors, wearable materials, and multifunctional aerospace structures. A typical system consists of stiff rectangular plate like scales embedded in a softer media and arranged periodically. Experimentally, these systems indicate pronounced nonlinear strain stiffening behavior even when the underlying substrate strains are small. However, capturing these behaviors using commercial finite element (FE) codes has proved difficult due to multiple sliding contacts between the scales after engagement. Therefore, accurate and reliable analytical models of architecture-property-relationships are needed for analysis and design. This thesis investigates the contact kinematics and mechanics …

Characterizing The Material Response Of The Passive Myocardium, Mehlil Ahmed

Graduate Thesis and Dissertation 2023-2024

Cardiovascular diseases remain a major public health concern worldwide, with heart failure emerging as a significant contributor to morbidity and mortality. Among heart failure cases, Heart Failure with preserved Ejection Fraction (HFpEF) presents a substantial clinical challenge due to its poor understanding and diagnostic complexity. Despite its prevalence, HFpEF lacks accurate diagnostic tools, hindering effective prognosis and therapy planning. This study addresses the knowledge gap surrounding HFpEF and diastolic dysfunction by focusing on the passive myocardial response during atrial systole, a critical yet understudied aspect of cardiac function. Current clinical measures, such as left ventricular ejection fraction, have limitations in …

A Study Of The Effects Of Microgravity Through Porous Media In Microfluidic Devices, Taylor A. Peterson

Graduate Thesis and Dissertation 2023-2024

In recent years, space exploration has been driving studies that enable sustained human presence in space. In such studies, fluidics relating to biology have become important. Fluids in biological systems span from large-scale flows relevant to circulatory, digestion, and pulmonary systems, but also involve many micro-scale porous flows. Hence, space exploration is driving a novel need to characterize fluidics in microscales in microgravity conditions. In this work, we study the porous flow network within bones that stimulates cellular growth and has the potential to relate to osteoporosis (including driving osteoporosis in astronauts). To study this effect, computational fluid dynamics (CFD) …

Madly In Love: A Meditation On The Capacity Of Love And Madness, Sarah Jane

CGU Theses & Dissertations

"Madly in Love" contends that madness is not merely a condition to be pathologized buta 'supernatural' universal energy that transcends realms, moving through and around all bodies and leaving profound bio-physiological imprints. This dissertation introduces the concept of neo- madness, which recognizes the intricate interplay between this ethereal energy and the corporeal, reshaping our understanding of mental health. This work calls for a radical reimagining of how we witness, honor, and engage with madness by adopting a neo-mad love discourse, methodology, and pedagogy. It centers critical love, a blend of empathy, compassion, and active critical engagement, as essential to creating …

The Automated Fourth Amendment, Maneka Sinha

Emory Law Journal

Courts routinely defer to police officer judgments in reasonable suspicion and probable cause determinations. Increasingly, though, police officers outsource these threshold judgments to new forms of technology that purport to predict and detect crime and identify those responsible. These policing technologies automate core police determinations about whether crime is occurring and who is responsible.

Criminal procedure doctrine has failed to insist on some level of scrutiny of—or skepticism about—the reliability of this technology. Through an original study analyzing numerous state and federal court opinions, this Article exposes the implications of law enforcement’s reliance on these practices given the weighty interests …

Analysis Of Research On The Effects Of Auditory Stimulation On Anxiety And Stress In Clinical And General Populations, Rebecca Lee

CMC Senior Theses

The use of auditory stimulation may be a useful method in treating clinical anxiety disorders, as well as aiding in coping with daily stress among general populations. The understanding of how certain forms of auditory stimulation can increase anxiety and stress is also critical so clinicians and the general population can approach decreasing anxiety and stress in the most effective way possible. The following paper will provide a literature review on studies published after the year 2000, analyzing the various impacts of different types of auditory stimulation, including impacts of music-therapy, music and noise at different frequencies, binaural beat stimulation, …

Threshold Concepts In Quantitative Reasoning, Judith Canner, Jennifer E. Clinkenbeard

Numeracy

The idea of “threshold concepts” has been used to identify discipline-based concepts that are critical to that academic area. Threshold concepts are often difficult for students to assimilate in a meaningful way but, once done, can be powerful for the learner. In general, threshold concepts are 1) transformative to learner thinking; 2) bounded by the discipline; 3) integrative with other concepts; and 4) irreversible once understood (Meyer and Land 2003). This paper presents five threshold concepts in quantitative reasoning (QR) developed by transdisciplinary faculty workgroups that may be applicable for non-mathematics disciplines as well. They are as follows: 1) QR …

The Standing Of Anger: Insights From The Debate(S) On Constructed Emotion, Andrew Holzer

CMC Senior Theses

In her book, Anger and Forgiveness: Resentment, Generosity, Justice, Martha Nussbaum argues that anger is inherently flawed because it fundamentally contains the desire for payback. To support her argument, she posits specific metaphysical claims about the nature of emotions like anger. This thesis is an extended critique of her metaphysical foundation from the perspective of empirical research in the neuroscience of emotion. The first reason to dispute this picture is descriptive; this view of anger is based on an outdated version of cognitive appraisal theory, which sees emotions as triggered directly by static moments of cognitive appraisal. The second …