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Enhancing Medical Cybersecurity: A Machine Learning Solution For Intrusion Detection In Iomt Devices, Afra Yaqoob

Theses

In the past few decades, the healthcare sector has undergone major technological advancements, which have included the adoption of Internet of Medical Things (IoMT), and networked medical devices. These advancements have changed the manner in which patient care is provisioned, enabling for more accurate diagnosis, personalized treatment plans, among other benefits. However, as healthcare providers are growing more reliant on interconnected systems, they have also been exposed to critical cybersecurity vulnerabilities. Medical devices have now become targets for cyberattacks, threatening patient data and its security and endangering patient's health and safety. This thesis examines the affects that inadequate cybersecurity measures, …

Small Angle X-Ray Scattering And Form Factor Modeling Of Β Crystallins - A Physiologically Significant Eye Lens Cytoplasm Protein, Srijan Banerjee

Theses

This thesis provides in depth analysis of small angle x-ray scattering (SAXS) experiments conducted on the beta-high crystallin eye lens cytoplasm protein. In particular, radius of gyration and molecular weight measurements are extracted and compared to measurements from existing work. Furthermore, an approach to math ematically modeling the scattering ”form-factor”, which describes the size and shape of individual particles, is also developed and applied to the SAXS data. The model acheived in the thesis appears to agree closely with scattering data at the low q range. Several obstacles which impede the resulting modeling from perfectly characterizing the data at higher …

Modeling Impact Of Simulated Myocardial Perfusion On Cardiac Ablation For Arrhythmia, Brendan Cappon

Theses

Bioheat transfer is the study of heat transfer applied in anatomy and physiology, which is relevant to maintaining homeostatic conditions from metabolic activity, thermal exposures, and various treatments and diagnostic methods. Blood flow significantly impacts heat transfer throughout the body, facilitating the diffusion of heat. Models have been developed to quantify bioheat transfer and the effect of blood flow through tissue for many biological functions and medical procedures, one of which is radiofrequency ablation for cardiac arrhythmia. Significant improvements to models and assumptions are still required as success rates for this procedure remain low for various arrhythmia types. The research …

Talimogene Laherparepvec (T-Vec) And Emerging Intralesional Immunotherapies For Metastatic Melanoma: A Review, Peter Mcgranaghan

All Publications

Purpose of review: As the incidence of cutaneous melanoma continues to rise worldwide, its heterogeneous presentation proves challenging for managing and preventing relapse.

Recent findings: While surgery remains a mainstay in staging and treatment of locoregional metastatic melanoma, intralesional therapies have emerged as a new tool to treat unresectable in-transit and nodal metastases and reduce the risk of relapse through immunomodulatory mechanisms. In this review, we will provide an overview of intralesional therapies for melanoma with a particular focus on talimogene laherparepvec (T-VEC) and its future uses. We then discuss the landscape of current and emerging intralesional therapies.

The Inclusion Of Metacognition In Source Evaluation Instruction, Anthony Tardiff

Communications in Information Literacy

Though the ACRL Framework holds metacognition as crucial to exercising information literacy, its emphasis was reduced from prominence in early drafts to a single mention in the final document. At the same time, few of the frequently-taught sets of source evaluation criteria include a step for self-awareness. This raises the question: do librarians explicitly teach metacognitive concepts when they teach source evaluation? Online library guides about source evaluation from various colleges and universities in Washington state were analyzed, and librarians who taught source evaluation were surveyed to determine whether and to what extent metacognitive concepts were included as part of …

Metabolic Shifts In Ratio Of Ucocn To Cocn Toward Bone Resorption Contribute To Age-Dependent Bone Loss In Male Mice, Matthew Bernhard, Obinna Okorie, Wei-Ju Louis Tseng, Mengcun Chen, Julia Danon, Mingshu Cui, Elisabeth Lashbrooks, Yanmei Yang, Bin Wang

Center for Translational Medicine Faculty Papers

The study of the senile osteoporosis in men still lags significantly behind that in women. The changes of protein molecule levels and their relationships with bone loss remain poorly understood. In the present study, we used C57BL/6J male mice at ages from 3 to 24 mo to delineate the mechanisms of aging effects on bone loss. We used the microcomputed tomography, mechanical testing, histomorphometry assays, and detection of serum levels of undercarboxylated osteocalcin (ucOcn) and carboxylated osteocalcin (cOcn) to assess bone mass changes and their relationships with the ratios of ucOcn-to-cOcn in mice from different age groups. The results showed …

The Effectiveness Of Mbsr On The Occupational Stress Of Correctional Officers, Nikolas Kerr

Dissertations

This dissertation looks at the negative effects of the work environment and other factors related to correctional officers lived experience. The intervention concentrates on the effect of mindfulness-based stress reduction on the occupational stress of correctional officers. Correctional officers have always dealt with difficult work conditions, but over the last 30 years the increase in the number of incarcerated people, the lack of retention among correctional officers, and the proliferation of inmates with complex mental health issues and gang affiliations have all created a much more complex and dangerous work environment. Combine this with the new understanding of the effects …

Incorporating Meditation, Yoga, And Reiki Interventions To Reduce Stress, Anxiety, And Mood Symptoms Among The College Population, Kelly Wills

Dissertations

The purpose of this clinical research project is to examine the efficacy of mindfulness techniques and alternative therapeutic practices, specifically, meditation, yoga, and Reiki, in decreasing symptoms of anxiety among college students. The increasing prevalence of anxiety disorders among the college population warrants the need for identifying effective interventions for enhancing mental health outcomes. This review integrates findings from published studies that focus on the impact of these practices on anxiety-related symptoms within college settings. Reviewing these studies reveals consistent evidence to support the effectiveness of mindfulness meditation as it relates to anxiety reduction as well as improvements in emotional …

Impact Of Place Based Learning On Community Engagement And Ownership, Alexis Mendez

Capstone Projects and Master's Theses

Place-based learning (PBL) offers an educational approach that emphasizes local history, environments, and communities, allowing students to engage with relevant content through the expertise gained from lived experiences. By utilizing their immediate surroundings, students are able to absorb educational material and foster a sense of place that can encourage civic engagement, environmental stewardship, and community ownership. This senior capstone research project explores the potential to enhance community ownership and engagement in Salinas, California through a Problem-Based Learning (PBL) approach. This project integrates the local geological and cultural history of California, Monterey Bay, and the Salinas Valley, alongside hands-on water quality …

Parenting With Grace, Eva Nelson Cole

Capstone Projects and Master's Theses

Parents are often caught off guard by the upheaval of adding children to their lives. Feelings of guilt, shame, isolation, and depression can arise when parents are faced with the demands and stressors that come along with having children. Studies have shown that children who have distressed parents endure lasting negative outcomes that can extend into the primary school years (Mihelic et al., 2018). Educating parents and giving them some awareness about what to expect can make a real difference. To have these conversations, I created a two-part parenting workshop for new parents at Parents’ Place in Pacific Grove, CA. …

Increasing College Students' Awareness Of Stress, Mental Health, And Well-Being, Marlene Villicana

Capstone Projects and Master's Theses

College students face many stressors due to the transitions and responsibilities of young adulthood. According to Karyotaki et al. (2020), 93% of respondents in an international study of college students reported at least one type of mild stress, and 73% named stress in at least three life areas. The same study found that stress management interventions effectively reduce perceived stress, mood, and anxiety problems through a combination of problem-focused and appraisal-focused strategies. In order to address the issues of stress, mental health, and well-being among college students, I created an interactive two-day presentation for Human Development and Family Science students …

Addressing Ethical Issues In Healthcare Artificial Intelligence Using A Lifecycle-Informed Process, Benjamin X Collins, Jean-Christophe Bélisle-Pipon, Barbara J Evans, Kadija Ferryman, Xiaoqian Jiang, Camille Nebeker, Laurie Novak, Kirk Roberts, Martin Were, Zhijun Yin, Vardit Ravitsky, Joseph Coco, Rachele Hendricks-Sturrup, Ishan Williams, Ellen W Clayton, Bradley A Malin, Bridge2ai Ethics And Trustworthy Ai Working Group

Faculty, Staff and Student Publications

OBJECTIVES: Artificial intelligence (AI) proceeds through an iterative and evaluative process of development, use, and refinement which may be characterized as a lifecycle. Within this context, stakeholders can vary in their interests and perceptions of the ethical issues associated with this rapidly evolving technology in ways that can fail to identify and avert adverse outcomes. Identifying issues throughout the AI lifecycle in a systematic manner can facilitate better-informed ethical deliberation.

MATERIALS AND METHODS: We analyzed existing lifecycles from within the current literature for ethical issues of AI in healthcare to identify themes, which we relied upon to create a lifecycle …

Targeting The Glutamine-Arginine-Proline Metabolism Axis In Cancer, Di Wang, Jiang-Jie Duan, Yu-Feng Guo, Jun-Jie Chen, Tian-Qing Chen, Jun Wang, Shi-Cang Yu

Faculty, Staff and Student Publications

Metabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism. This axis also acts as a scaffold for the synthesis of other nonessential amino acids and essential metabolites. In this paper, we briefly review (1) the glutamine addiction exhibited by tumour cells with accelerated glutamine transport and metabolism; (2) the methods regulating extracellular glutamine entry, intracellular glutamine synthesis and the fate of intracellular glutamine; (3) the glutamine, proline and arginine metabolic pathways and their interaction; and (4) the research progress in tumour therapy …

Genetic Ablation Of The Isoform Γ Of Pi3k Decreases Antidepressant Efficacy Of Ketamine In Male Mice, Gabriela N Vaz, Flávia C Turcato, Isabel A V Lima, Franciele F Scarante, Melissa R Araújo, Tamires A V Brigante, Livia C M Rodrigues, Francisco S Guimarães, Jaime E C Hallak, Jose A Crippa, Antonio L Teixeira, Antonio C P De Oliveira, Alline Cristina Campos

Faculty, Staff and Student Publications

About one-third of major depressive disorder (MDD) patients demonstrate unresponsiveness to classic antidepressants, and even the clinical efficacy of fast-acting drugs such as ketamine varies significantly among patients with treatment-resistant depression. Nevertheless, the lack of suitable animal models that mimic a possible ketamine-resistant phenotype challenges the understanding of resistance to drug treatment. In this study, we showed that PI3Kγ knock-out (KO) mice do not respond to classical doses of ketamine and classical antidepressants. PI3Kγ KO mice were unresponsive to both the rapid and sustained antidepressant-like effects of a single dose of ketamine in the forced swimming test. Additionally, they were …

A150: Analysis Of The Mechanism Of Resveratrol's Action On Myocardial Energy Metabolism In Exercise-Induced Fatigue Rats, Shang Xu, Jinru Cai, Yulong Hu

International Journal of Physical Activity and Health

Background/Purpose: Promotional effects of resveratrol on myocardial mitochondrial energy metabolism in exercise-induced fatigue rats were investigated by network pharmacology and animal experiments.

Method: In the present study, the effects of resveratrol on myocardial energy metabolism were assessed using network pharmacology with enrichment analysis. Forty-eight healthy male SD rats of 6–8 weeks of age were selected and randomly divided into blank control group (C), resveratrol administration group (R), exercise fatigue group (E), and exercise fatigue + resveratrol administration group (ER) with 12 rats in each group. Rats in E group and the exercise fatigue + ER group were weight-bearing 5% swimming …

Kaupa Letters: Volume 12, Issue 2, Korean American University Professors Association

KAUPA Letters

No abstract provided.

Leveraging Ai Tools In University Writing Instruction: Enhancing Student Success While Upholding Academic Integrity, Daisuke Akiba, Rebecca Garte

Publications and Research

The emergence of AI-powered Large Language Models (LLMs), such as ChatGPT and Google Gemini, presents both opportunities and challenges for higher education, particularly regarding academic integrity in writing instruction. This exploratory study examines a novel pedagogical approach that integrates LLMs as required feedback tools in a university-level psychology writing assignment. The exclusive online approach emphasizes improvement through revision, requiring students to obtain AI-generated feedback on ungraded initial drafts based on an instructor-provided rubric, with final assessment focused on the quality of subsequent revisions. Analysis of survey data from 39 undergraduate students, incorporating both quantitative measures and qualitative responses, revealed several …

Patterns In Gray Wolf Pup Survival And Recruitment In Northern Minnesota, Andrea Hynes

All NMU Master's Theses

Knowledge of how and why the vital rates of wildlife populations change through and over time is crucial for understanding wildlife population dynamics. Because estimating gray wolf pup survival is challenging, our understanding of pup survival and the factors influencing survival and recruitment is limited. I used a combination of litter counts and video observations from a large remote camera array to estimate annual wolf pup survival and recruitment and to evaluate intra-annual patterns in pup survival and recruitment within the Greater Voyageurs Ecosystem, MN, USA. Mean annual pup survival during 2019–2023 was 0.24, and the mean annual recruitment rate …

Sensitive Grip Mounting Surfaces For Physical Human-Robot Interaction., Branden Shay

Electronic Theses and Dissertations

As the development of robotics becomes ever increasingly present in our society, the need for studying how humans and robots interact with each other becomes more of a necessity to be properly integrated in the changing world around us. In this thesis, we undertake the study and development of how to create a tactile human-robot operator interface to guide a robot perform a physical task. The implementation of tactile interfaces such as SkinCell sensor arrays emulating skin, and of a robotic handlebar fitted with tactile sensors are critical examples of the challenges that come with mounting and packaging such sensors …

Viking And Native North American Interactions: The Spread Of Disease In The Norse Discovery Of North America, Sarah N. Haughawout

Undergraduate Honors Capstone Projects

This paper evaluates the potential for spread of disease in the Norse and Native North American interactions around 1000 CE. At this time, the Vikings were expanding their territory in search of land and natural resources following the Viking Raids in mainland Europe. They traveled to Iceland, then Greenland, and finally the eastern coast of northern Canada. Norse explorers faced numerous obstacles on their journeys, but they still prospered in North America for a time. The Vikings hunted the land and sea mammals, used the land, and found ways to thrive while having hostile relations and contact with the Native …

Preventing Depression In Grandparents Raising Grandchildren: An Educational Video Series, Sabrina Casares

Student Capstone Papers

This paper presents a doctoral capstone project that created and implemented a self-help occupation-based educational video series to prevent and manage depression among grandparent caregivers. It consists of a literature review regarding the impact of depression on grandparent caregivers, the population’s barriers and statistics relating to the correlation of developing depression as a grandparent caregiver. It includes the process to create the video series including review of the literature and the development process. Texas Grandparents Raising Grandchildren (TXGRG) is a non-profit organization dedicated to providing resources and support to empower and advocate for grandparent caregivers. Problem: There is a lack …

A Theory-Guided Qualitative Exploration Of Occupational Influences On Firefighters’ Dietary Behaviors, Cynthia Horton Dias, Courtney Catledge Dnp, Msn, Aprn, Fnp-Bc, Robin M. Dawson Phd, Rn, Cpnp-Pc

Publications

Background: Firefighters face many inherent occupational health hazards and increased risk for several cancers, making peak health essential. However, cardiac events and stroke continue as leading causes of on-duty deaths. Healthy diets promote prevention of cardiovascular disease and cancers. While some dietary interventions have been undertaken, sustained improvements have not been observed. Understanding firefighters’ occupational influences on dietary behavior is vital for implementation of effective interventions to improve nutrition. Methods: The Theoretical Domains Framework (TDF) guided this qualitative study. Nine focus groups of firefighters who work 24-hour shifts and one interview with a fire administrator (N = 34) were conducted …

Molecular Pathways Of Odontogenic Keratocysts: A Systematic Review, Paolo Boffano, Francesca Neirotti, Matteo Brucoli, Muhammad Ruslin

Journal of Dentomaxillofacial Science

The odontogenic keratocyst (OKC) stands out as one of the most prevalent odontogenic tumors. Since its initial description, numerous studies have delved into various aspects of this lesion, aiming to unravel its distinctive biological behavior.

Recent investigations have specifically focused on the molecular aspects of OKC, shedding light on its biological characteristics. Substantial differences at the molecular level between OKC and other odontogenic cystic lesions indicate a distinct biological origin. Genetic and molecular research in the realm of odontogenic tumors, particularly OKC, has contributed significantly to the growing knowledge and understanding of their physiopathological pathways. The molecular findings may open …

Effectiveness Of Picture Exchange Communication System(Pecs) In Improving Tooth Brushing Ability Of Children With Autism Spectrum Disorder(Asd), Syakriani Syahrir, Andi Am. Putri, Karima Q. Mansjur, Aisyah K. Yunus

Journal of Dentomaxillofacial Science

Objective: This study assesses the efficacy of the Picture Exchange Communication System (PECS) in enhancing tooth brushing skills in children with Autism Spectrum Disorder (ASD).

Material and Method: The research utilized a prospective interventional strategy, encompassing 54 children aged 4 to 18 years with Autism Spectrum Disorder (ASD). Participants were trained across two sessions, separated by a two-week interval, to adhere to a systematic tooth-brushing protocol utilizing PECS. The data collection involved assessing Oral Hygiene Index Scores (OHIS) at 5 and 10 days following the intervention and maintaining a diary to document participants' daily tooth brushing habits as reported by …

Effectiveness Of Cabbage (Brassica Oleracea Var. Capitata L.) Against Streptococcus Mutans, Staphylococcus Aureus And Porphyromonas Gingivalis Bacteria, Irene E. Rieuwpassa, Nurlindah Hamrun, Maria Tanumihardja, Juni J. Nugroho, Risfah Yulianty, Sherlie Diana, Yogie M. Arief, Nur F. Said, Rezky A. Putri, Boy M. Bachtiar, Heni Susilowati, Retno I. Roestamadji

Journal of Dentomaxillofacial Science

Objective: Therefore, this study was aimed at examining the inhibition of green cabbage and purple cabbage against oral pathogenic bacteria and knowing the nitrate content and the theoretical benefits of nitrate in cabbage as a prebiotic material that supports oral and dental health including systemic body health by lowering blood pressure.

Material and Methods: The type of research to be used is laboratory experimental with the post test only control group. Preparation of green cabbage and purple cabbage extracts with maceration technique. Dilution was carried out so that the concentration of green cabbage and purple cabbage extracts was …

Mental Index, Antegonial Index, And Mandibular Cortical Index For Assessment Of Bone Quality Using Panoramic Radiograph, Supriyadi, Swasthi Prastyarini, Lusi Hidayati, Agus Sumono, Yohana M. Penga, Susi W. Asih

Journal of Dentomaxillofacial Science

Background: Several indices for measuring the thickness of the mandibular cortex using a panoramic radiograph have been developed. Indices enable measurements to assess bone quality (bone mineral density/BMD). This study aims to identify bone quality through mental index (MI), antegonial index (AI), and mandibular cortical index (MCI) measurements using a panoramic radiograph. 

Materials and method: The observational study used a cross-sectional research design. The population was panoramic radiographs of patients in the Radiology installation of the University of Jember Dental Hospital. The samples consisted of 87 panoramic radiographs that met the criteria inclusion: Region of Interest (ROI), i.e., …

Influential Nature Of Empathy In The Relationship Between Psychopathy And Aggression, Alessia M. Valentino

Student Theses

Past research discusses the development of psychopathy and its association with aggression and empathy. It highlights that while personality traits central to psychopathy are believed to arise early in life, adolescence is a critical period where these traits interact and manifest in behaviors. Some research discusses the role of empathy in moderating aggressive behavior, suggesting that interventions targeting empathy could potentially reduce aggressive and antisocial behaviors in individuals with psychopathic traits. The current study explores the relationship between psychopathic traits, empathy, and aggression in adolescents, aiming to enhance our understanding of these complex constructs and their implications for risk assessment …

Comparison Of Methods For Amphetamine Enantiomer Analysis Using Hplc And 1h-Nmr, Martin Mai

Student Theses

A molecule is chiral if it cannot be superimposed on its mirror image. Chiral drugs exist as these mirror image enantiomers, which can differ in their pharmacological effects. When a drug’s active molecule exists as a pair of enantiomers, the relative ratio of each enantiomer in the final product can provide information about the source of production for this drug, i.e., whether the drug was legally or illegally produced. However, typical detection methods may not differentiate between enantiomers of a chiral molecule. This thesis study compares three different methods for enantiomer detection of amphetamine, which is a drug often prescribed …

The Effects Of Multiple Acute Turkesterone Doses On Indirect Measures Of Hypertrophy And Metabolic Measures: A Preliminary Investigation, Dillon R. Harris, Tomas Chapman-Lopez, Steven B. Machek, Jeffery S. Forsse, Tracey Sulak, Leslee K. Funderburk

Kinesiology Faculty Publications and Presentations

Turkesterone is a naturally occurring plant steroid touted for its medicinal, pharmacological, and biological properties with no reported adverse side effects compared with traditional anabolic androgenic steroids (AAS). However, this ostensible enhancement to increase muscle protein synthesis and facilitate augmented thermogenesis remains undescribed despite uninformed and potentially haphazard consumption. To investigate whether turkesterone enhances insulin-like growth factor-1 (IGF-1) and resting metabolic rate (RMR), eleven apparently healthy males (23.3 ± 2.2) volunteered to participate in the present study with samples collected pre-, 3H post-, and 24H post-ingestion. Subsequent analyses failed to reveal any significant main condition, time, or interaction main effects …

Who Adds Lc16m8 Mpox Vaccine To Emergency Use Listing

Saudi Medical Journal

No abstract provided.