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Articles 541 - 570 of 11606
Full-Text Articles in Entire DC Network
Impact Of Climate Change On Maternal Health In Pakistan: A Review Paper, Ihsan Ullah, Kiran Mubeen, Dilshad Begum, Rafat Jan
Impact Of Climate Change On Maternal Health In Pakistan: A Review Paper, Ihsan Ullah, Kiran Mubeen, Dilshad Begum, Rafat Jan
Journal of Asian Midwives (JAM)
Pakistan is one of the country’s most susceptible to the effects of climate change. Recent floods, heavy snowfall and rain have significantly impacted maternal and infant health. Indigenous women of child-bearing age especially those in rural areas are among the most vulnerable, facing food insecurity, disruptive food systems, rising food prices, and disrupted food production due to climate change. This review highlights a critical gap in research on indigenous women's maternal nutrition in the context of climate change, particularly in low- and middle-income countries. It emphasized the necessity for culturally responsive approaches and a deeper understanding of how climate change …
Detecting, Attributing, And Projecting Global Marine Ecosystem And Fisheries Change: Fishmip 2.0, Julia L. Blanchard, Camilla Novaglio, Olivier Maury, Cheryl S. Harrison, Colleen M. Petrik, Denisse Fierro-Arcos, Kelly Ortega-Cisneros, Andrea Bryndum-Buchholz, Tyler D. Eddy, Ryan Heneghan, Kelsey Roberts, Jacob Schewe, Daniele Bianchi, Jerome Guiet, P. Daniel Van Denderen, Juliano Palacios-Abrantes, Xiao Liu, Charles A. Stock, Yannick Rousseau, Matthias Büchner, Ezekiel O. Adekoya, Cathy Bulman, William Cheung, Villy Christensen, Marta Coll, Leonardo Capitani, Samik Datta, Elizabeth A. Fulton, Alba Fuster, Victoria Garza, Matthieu Lengaigne, Max Lindmark, Kieran Murphy
Detecting, Attributing, And Projecting Global Marine Ecosystem And Fisheries Change: Fishmip 2.0, Julia L. Blanchard, Camilla Novaglio, Olivier Maury, Cheryl S. Harrison, Colleen M. Petrik, Denisse Fierro-Arcos, Kelly Ortega-Cisneros, Andrea Bryndum-Buchholz, Tyler D. Eddy, Ryan Heneghan, Kelsey Roberts, Jacob Schewe, Daniele Bianchi, Jerome Guiet, P. Daniel Van Denderen, Juliano Palacios-Abrantes, Xiao Liu, Charles A. Stock, Yannick Rousseau, Matthias Büchner, Ezekiel O. Adekoya, Cathy Bulman, William Cheung, Villy Christensen, Marta Coll, Leonardo Capitani, Samik Datta, Elizabeth A. Fulton, Alba Fuster, Victoria Garza, Matthieu Lengaigne, Max Lindmark, Kieran Murphy
Faculty Publications
There is an urgent need for models that can robustly detect past and project future ecosystem changes and risks to the services that they provide to people. The Fisheries and Marine Ecosystem Model Intercomparison Project (FishMIP) was established to develop model ensembles for projecting long-term impacts of climate change on fisheries and marine ecosystems while informing policy at spatio-temporal scales relevant to the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) framework. While contributing FishMIP models have improved over time, large uncertainties in projections remain, particularly in coastal and shelf seas where most of the world's fisheries occur. Furthermore, previous FishMIP climate …
Evaluating Consumers' Acceptability Of Laser-Labeled Apple Fruit, Durga Khadka, Martin J. Talavera, Eleni D. Pliakoni, Logan L. Britton, Londa Nwadike, Manreet S. Bhullar
Evaluating Consumers' Acceptability Of Laser-Labeled Apple Fruit, Durga Khadka, Martin J. Talavera, Eleni D. Pliakoni, Logan L. Britton, Londa Nwadike, Manreet S. Bhullar
Dairy Science and Food Science Faculty Publications: 2022 to Present
Fresh produce is traditionally labeled with plastic Price LookUp (PLU) stickers that are environmental contaminants and can easily detach during handling and disrupt traceability. The CO2 laser-labeling technology (LLT), an alternate method of produce labeling, has been gaining attention. However, the performance of this technology varies by produce, and consumer perception and acceptability remain understudied. The study evaluated consumers' perception and acceptability of the laser-labeled apple fruit that were purchased locally, laser-printed with a QR code, and coated with edible wax. A consumer study (N = 75) was conducted using 1) Apple with QR-code, 2) Apple with PLU plastic …
Low Public Awareness Opens Up New Opportunities For Highlighting Milk As An Iodine Dietary Source, Giovanni Niero, Simona Censi, Caterina Mian, Carmen L. Manuelian, Maristela Rovai, Eleni Tsiplakou, Luciana Da Costa, Et.Al
Low Public Awareness Opens Up New Opportunities For Highlighting Milk As An Iodine Dietary Source, Giovanni Niero, Simona Censi, Caterina Mian, Carmen L. Manuelian, Maristela Rovai, Eleni Tsiplakou, Luciana Da Costa, Et.Al
Dairy Science and Food Science Faculty Publications: 2022 to Present
No abstract provided.
Nursing News & Views - December 2024, Joanne Miller Rn
Nursing News & Views - December 2024, Joanne Miller Rn
Nursing Newsletters
Nursing News & Views - December 2024
Food At Sea On The Late Antique Mediterranean, Andrew Donnelly, Justin Leidwanger
Food At Sea On The Late Antique Mediterranean, Andrew Donnelly, Justin Leidwanger
Faculty Publications
No abstract provided.
Irradiation Enhanced Immune Response In Esophageal Squamous Cell Carcinoma, Ansah Mirza
Irradiation Enhanced Immune Response In Esophageal Squamous Cell Carcinoma, Ansah Mirza
2024 Fall Honors Capstone Projects - Archive
Esophageal squamous cell carcinoma (ESCC) is a significant challenge due to its limited treatment options and poor prognosis. This study aimed to understand the irradiation induced cellular changes in ESCC cells to search for a better combination of radiotherapy and immunotherapy for ESCC patients through studying the effects of programmed death ligand-1 (PD-L1) and calreticulin (CRT), major cell immunogenicity markers. This research investigated the change in PD-L1 expression, CRT translocation, and how it impacted a cancer cell’s immune response. The human ESCC cell line, KYSE-150, was cultured and underwent irradiation. Images of the cells were taken using the Nikon A1R …
Examining The Risk Of Cardiovascular Disease Among African American College Students At The University Of Texas At Arlington, Esha Kashyap
Examining The Risk Of Cardiovascular Disease Among African American College Students At The University Of Texas At Arlington, Esha Kashyap
2024 Fall Honors Capstone Projects - Archive
Many studies examine the risk of cardiovascular disease in the general population of African Americans adults compared with other racial and ethnic groups; however, there is limited research that explores the risk factors, discrimination, and food behavior that impact this group. Cardiovascular disease develops over time and certain practices or experiences can increase the risk of this disease; thus, studying the behavior and perceptions of college students is important. Therefore, this research examined whether food behavior and perceived discrimination was higher in African American college students than in other racial or ethnic student groups. Utilizing a survey containing both qualitative …
Investigating The Acute Physiological Effects Of Effluent Crystal Violet On The Freshwater Bioindicator Daphnia Pulex, Hoang K. Ho
Investigating The Acute Physiological Effects Of Effluent Crystal Violet On The Freshwater Bioindicator Daphnia Pulex, Hoang K. Ho
2024 Fall Honors Capstone Projects - Archive
This study examines the effects of acute exposure to crystal violet (CV) on the freshwater zooplankton Daphnia pulex in response to growing concerns over synthetic dyes from industrial runoff in aquatic ecosystems. The primary objective is to assess CV's impact on D. pulex's heart rate, mobility, morphology, and lethality via a series of acute exposure tests. 48-h acute toxicity (0-2000 μg/L), 48-h immobilization (0-180 μg/L), and 9-h heart rate (0-2,000 μg/L) tests were conducted using third-generation daphnids, followed by stereomicroscopic examination and statistical analysis. Results showed increasing mortality and decreasing mobility and heart rate with increasing CV concentration; the …
Investigating The Role Of Hopelessness In The Stress-Performance Relationship Among College Students, Vidushi Sabnani
Investigating The Role Of Hopelessness In The Stress-Performance Relationship Among College Students, Vidushi Sabnani
2024 Fall Honors Capstone Projects - Archive
As college students pursue higher education as a pathway to success, they face pressures that threaten their well-being and academic success. Balancing academic, financial, and social demands has led to a mental health crisis on campuses, with emotional stress cited as the leading cause of students discontinuing their education (Gallup, 2023). This study investigates the relationship between academic stress, perceived stress, and academic performance in college students. It also examines the Yerkes-Dodson law of a curvilinear relationship between stress and performance and the role of hopelessness as a mediator. A sample of 321 participants completed surveys assessing academic stress, perceived …
The Periconceptional, Physical Activity, Environment, Nutrition And Diet (Prepared) Study, Aaliyah Devore
The Periconceptional, Physical Activity, Environment, Nutrition And Diet (Prepared) Study, Aaliyah Devore
McNair Scholars Research Journal
No abstract provided.
Assessing The Potential For Soil-Mediated Transmission Of Symbiotic Bacteria In The Leaffooted Bug (Leptoglossus Phyllopus), Armeen Nasir
Assessing The Potential For Soil-Mediated Transmission Of Symbiotic Bacteria In The Leaffooted Bug (Leptoglossus Phyllopus), Armeen Nasir
McNair Scholars Research Journal
Recent evidence suggests insects might indirectly provide symbionts to their offspring by releasing them into the soil via feces. We investigated whether this is occurring in the Eastern leaf-footed bug, Leptoglosuss phyllopus. We hypothesized that if adults release viable symbiont cells into their environment, then nymphs will have a higher survival rate, develop faster, and be larger at adulthood when exposed to soil that has been in contact with adult insects for longer. To measure the rate and whether the bugs acquired Caballeronia from the soil, insect nymphs were exposed to soil that had been exposed to a lab colony …
Labeling Energy Drinks: Tackling A Monster Of A Problem, Meredith P. Mulhern, Michael S. Sinha
Labeling Energy Drinks: Tackling A Monster Of A Problem, Meredith P. Mulhern, Michael S. Sinha
Journal of Food Law & Policy
Energy drinks first rose to popularity in the 1980s after the creation of Red Bull. In addition to high caffeine amounts, energy drinks often contain herbal stimulant additives, vitamin and mineral mixtures, and sugar. There is very little information available on the long-term effects of these stimulant mixtures on the body. Although many consumers purchase energy drinks because of their caffeine content, many are left in the dark when it comes to labeling transparency and are unaware of their true contents. Energy drinks are classified as dietary supplements, meaning they are not directly regulated by the FDA before hitting store …
Forced To Weather The Storm: Reforming The Livestock Indemnity Program To Improve Farm Animal Welfare, Cameron Krier Massey
Forced To Weather The Storm: Reforming The Livestock Indemnity Program To Improve Farm Animal Welfare, Cameron Krier Massey
Journal of Food Law & Policy
Each year, extreme weather events put the lives and wellbeing of millions of farm animals at risk. These events can lead to injury, suffering, acute and chronic stress, decreased productivity, and loss of life. As storms increase in frequency and intensity, efforts should be made to ensure livestock are protected. This paper proposes modifications to the Livestock Indemnity Program (LIP), a federally run disaster assistance program that compensates livestock owners and growers for animal deaths and reduced value caused by eligible conditions, including extreme weather. Surprisingly, the program does not require producers to show proof and use of a disaster …
Udder Confusion: An Almond Milk Case Study To Examine The Complex Interplay Of Consumer Choices, Social Media, And Regulation, Madeline Mcculloch
Udder Confusion: An Almond Milk Case Study To Examine The Complex Interplay Of Consumer Choices, Social Media, And Regulation, Madeline Mcculloch
Journal of Food Law & Policy
The preference for plant-based diet options has steadily increased for the American public. This is all particularly true for alternative milks. By the end of 2020, plant-based milk alternatives (“PBMA”) accounted for approximately fifteen percent of the total milk market and thirty-five percent of the overall plant-based market, making alternative milks, particularly almond, one of the most popular ways for people to dabble in a plant-based diet. Almond milk holds the gold in the U.S. plant-based milk market. It is, first, essential to examine the comprehensive context surrounding almond milks’ status on grocery shelves. This writing will attempt to do …
Proteolytic Manipulation Of Neutrophil Responses And The Efferocytic Synapse By Porphyromonas Gingivalis., Kelley N. Cooper
Proteolytic Manipulation Of Neutrophil Responses And The Efferocytic Synapse By Porphyromonas Gingivalis., Kelley N. Cooper
Electronic Theses and Dissertations
Porphyromonas gingivalis (Pg) is etiologically associated with chronic periodontitis, a highly prevalent chronic inflammatory disease characterized by the destruction of hard and soft tissues of the periodontium. Pg is adapted to live in the human oral subgingival niche, a hostile environment dominated by excessive numbers of activated neutrophils and antimicrobial mediators. Its survival is contingent upon prompt and effective inactivation of neutrophil effector functions. In this dissertation, I uncover a novel pathogenic mechanism employed by Pg that disarms the antimicrobial capacity of live neutrophils and simultaneously sequesters them within macrophages. Mechanistically, RgpB, a cysteine protease produced by Pg …
Differential Responses Of Human Neutrophils To Legionella Species., Hannah E. Hanford
Differential Responses Of Human Neutrophils To Legionella Species., Hannah E. Hanford
Electronic Theses and Dissertations
Legionella species are Gram-negative facultative intracellular bacterial pathogens commonly found in freshwater or soil environments where they survive and replicate within their natural protozoan hosts. Humans serve as an accidental host for Legionella species after inhalation of contaminated aerosolized water droplets or soil particles enabling the bacteria to enter the lungs, infect alveolar macrophages, and result in severe pneumonia. Evasion of degradation and proliferation within alveolar macrophages by Legionella species and manifestation of “Legionnaires’ disease” is dependent on the Dot/Icm type IV secretion system (T4SS). The T4SS apparatus is a needle-like channel for translocation of over ~350 effector proteins, depending …
Carroll County Advisory Council Minutes 2020, Mikayla Cerney
Carroll County Advisory Council Minutes 2020, Mikayla Cerney
UNH Cooperative Extension
No abstract provided.
Students Participating As Ambassadors For Research In Kentucky (Spark): A Health Equity Undergraduate Research Training Program, Ariel A. Arthur, Rebecca L. Delacerda Allen, Fidelis Y. Sesenu, Maxwell A. Groznik, Carrie B. Oser, Madeline Dunfee, Philip A. Kern, Nancy Schoenberg
Students Participating As Ambassadors For Research In Kentucky (Spark): A Health Equity Undergraduate Research Training Program, Ariel A. Arthur, Rebecca L. Delacerda Allen, Fidelis Y. Sesenu, Maxwell A. Groznik, Carrie B. Oser, Madeline Dunfee, Philip A. Kern, Nancy Schoenberg
UK CARES Faculty Publications
The Students Participating as Ambassadors for Research in Kentucky (SPARK) program provides novel health equity research training and targeted mentorship for undergraduates, particularly those from groups underrepresented in the biomedical and behavioral research and workforce. SPARK aims to address inadequate diversity in the medical and scientific research fields by providing comprehensive research mentorship and skill-building. Unlike most existing research training programs that are brief, focus on laboratory research, or are limited to graduate students and junior faculty, SPARK delivers a 16-month intensive behavioral and population health science training, equipping students with needed tools to conceptualize, plan, execute, and analyze their …
Evaluation Of Commercially Available Sanitizers Efficacy To Control Salmonella (Sessile And Biofilm Forms) On Harvesting Bins And Picking Bags, Colton Ivers, Samhitha Chalamalasetti, Blanca-Ruiz Llacsahuanga, Faith Critzer, Manreet Bhullar, Londa Nwadike, Umut Yucel, Valentina Trinetta
Evaluation Of Commercially Available Sanitizers Efficacy To Control Salmonella (Sessile And Biofilm Forms) On Harvesting Bins And Picking Bags, Colton Ivers, Samhitha Chalamalasetti, Blanca-Ruiz Llacsahuanga, Faith Critzer, Manreet Bhullar, Londa Nwadike, Umut Yucel, Valentina Trinetta
Dairy Science and Food Science Faculty Publications: 2022 to Present
This study evaluated the efficacy of five commercially available sanitizers to reduce Salmonella (sessile and biofilm forms) count on experimentally inoculated materials representative of harvesting bins and picking bags in the fresh produce industry. Sessile Salmonella cells were grown onto tryptic soy agar to create a bacterial lawn, while multistrain Salmonella biofilms were grown in a Centers for Disease Control and Prevention (CDC) reactor at 22 ± 2 °C for 96 h. Samples were exposed to 500 ppm free chlorine, 500 ppm peroxyacetic acid (PAA), 75 psi steam, and 5% silver dihydrogen citrate (SDC) for 30 sec, 1, or 2 …
Rumen-Protected Methionine Supplementation Improves Lactation Performance And Alleviates Inflammation During A Subclinical Mastitis Challenge In Lactating Dairy Cows, A. Paz, T.C. Michelotti, M. Suazo, J. Bonilla, M. Bulnes, A. Minuti, D. Luchini, E. Trevisi, A.F. Lima, J. Halfen, M. Rovai, J.S. Osorio
Rumen-Protected Methionine Supplementation Improves Lactation Performance And Alleviates Inflammation During A Subclinical Mastitis Challenge In Lactating Dairy Cows, A. Paz, T.C. Michelotti, M. Suazo, J. Bonilla, M. Bulnes, A. Minuti, D. Luchini, E. Trevisi, A.F. Lima, J. Halfen, M. Rovai, J.S. Osorio
Dairy Science and Food Science Faculty Publications: 2022 to Present
This study aimed to evaluate the effects of rumen-pro- tected Met on lactation performance, inflammation, and immune response, and liver glutathione of lactating dairy cows during a subclinical mastitis challenge (SMC). Thirty-two Holstein cows (145 ± 51 DIM) were enrolled in a randomized complete block design. At −21 d relative to the SMC, cows were assigned to dietary treatments, and data were collected before and during the SMC. Cows were blocked according to parity, DIM, and milk yield and received a basal diet (17.4% CP; Lys 7.01% MP and Met 2.14% MP) plus 100 g/d of ground corn (CON; n …
A Preliminary Trauma-Informed Guide For School-Based Occupational Therapists And Other Disciplines To Address Students That Have Experienced Trauma, Chesney Friesenhahn
A Preliminary Trauma-Informed Guide For School-Based Occupational Therapists And Other Disciplines To Address Students That Have Experienced Trauma, Chesney Friesenhahn
Occupational Therapy Doctoral Capstones
This doctoral capstone experience focused on gaining expertise in trauma-informed and trauma-specific care to address the needs of school-aged children who had experienced psychological trauma. One of the objectives of this capstone project was to increase the understanding of acute, chronic, and complex trauma and the occupational impact that trauma could have on children within the school system. Existing research supported the role of occupational therapists in integrating trauma-informed care into practice to address trauma-related symptoms that interfered with rest, sleep, education, play, social participation, behavior, emotional regulation, sensory processing, and overall health and well-being. As revealed in the literature …
The Parental Perspective: Experiences And Challenges In Pediatric Feeding Therapy, Amber Brandmeyer
The Parental Perspective: Experiences And Challenges In Pediatric Feeding Therapy, Amber Brandmeyer
Occupational Therapy Doctoral Capstones
This capstone aimed to identify parent experiences in feeding therapy. The literature highlights the high prevalence of pediatric feeding disorder and avoidant restrictive food intake disorder among the pediatric population with the prevalence numbers growing in children with disabilities. Occupational therapists provide a unique contribution to a feeding therapy team, examining the diverse needs of every individual in a holistic manner including physical, developmental, cognitive, and psychosocial factors. Current literature often overlooks parent perspectives when looking at feeding therapy. Literature acknowledges the stress inducing nature of feeding therapy on parents but falls short in exploring viable solutions to these challenges. …
Letter From The Vice President For Research And Innovation, The Mcnair Team
Letter From The Vice President For Research And Innovation, The Mcnair Team
McNair Scholars Research Journal
No abstract provided.
Household Vegetable Gardening In Quezon City, Philippines: Practices, Benefits, And Constraints, John Luis D. Lagdameo, Angelica Nicolette B. Dejaresco, Ma. Cecilia M. Gonzales, Liz Ignowski, Pepijn Schreinemachers, Arma R. Bertuso
Household Vegetable Gardening In Quezon City, Philippines: Practices, Benefits, And Constraints, John Luis D. Lagdameo, Angelica Nicolette B. Dejaresco, Ma. Cecilia M. Gonzales, Liz Ignowski, Pepijn Schreinemachers, Arma R. Bertuso
Leadership and Strategy Faculty Publications
The study collected a wide range of information from respondents. It included details about their identities, such as names, ages, and genders. Additionally, it examined household characteristics, including house size, sources of income, and the number of floors in their homes. The research also explored urban food production and planting practices, identifying the types of vegetables grown, the locations of these planting activities, and the technologies used. Moreover, it investigated food acquisition and meal preparation, focusing on sources of food, safety concerns, and the challenges faced in obtaining these items. Diet diversity was assessed through a one-month recall of food, …
Physical Activity And Sport Participation: Relationships With General Life Satisfaction And Social Life Satisfaction, Clay Barker
Physical Activity And Sport Participation: Relationships With General Life Satisfaction And Social Life Satisfaction, Clay Barker
Honors College Theses
This study investigated the impact of college student physical activity and sport participation on life satisfaction and social life satisfaction. This study used a survey with scales to assess students’ frequency of physical activity, frequency of traditional sport participation, frequency of esport participation, life satisfaction, and social life satisfaction. This study’s hypotheses attempted to assess if each involvement variable will individually and positively correlate to both life satisfaction and social life satisfaction. This study used in-person surveys given to Murray State University college students. The findings of this study could provide information on the importance of physical activity and sport …
The Atheroprotective Impact Of Anti-Mir-33a-5p/3p In Cultured Pro-Inflammatory Endothelial Cells, Kun Huang
The Atheroprotective Impact Of Anti-Mir-33a-5p/3p In Cultured Pro-Inflammatory Endothelial Cells, Kun Huang
All Dissertations
Atherosclerosis is the process of cholesterol buildup within arterial cells, which is considered a leading factor that causes certain cardiovascular diseases. Cholesterol accumulation within pro-inflammatory endothelial cells is thought to induce atherogenesis and accelerate atherosclerosis progression. Evidence suggests inhibiting the microRNA miR-33a in arterial cells may promote atheroprotection via increasing ABCA1 protein expression. MiR-33a is processed into two functional strands, miR-33a-5p and miR-33a-3p. The potential atheroprotective effect of inhibiting miR-33a-5p and/or miR-33a-3p precisely in pro-inflammatory endothelial cells is not fully understood, as data is scant regarding what potential atheroprotective impact ABCA1-dependent cholesterol within pro-inflammatory endothelial cells demonstrates, which occurs via …
Scavenging As An Accelerant In The Postmortem Interval Estimate: Refining Quantitative Regressions For Decomposition Analyses In Southeast Nebraska, Jenna L. Alexander
Scavenging As An Accelerant In The Postmortem Interval Estimate: Refining Quantitative Regressions For Decomposition Analyses In Southeast Nebraska, Jenna L. Alexander
Department of Anthropology: Theses and Student Research
In forensic anthropology, the postmortem interval (PMI) is an estimation of the time elapsed from the moment of death to the point of discovery or examination. Contemporary approaches for estimating PMI have sought to refine broad quantitative regressions by addressing variance among intrinsic and extrinsic influences of decomposition at a regional level. Southeast Nebraska and the broader Great Plains region encompass one of the most influential agricultural ecosystems, featuring a unique climate type and a diverse spectrum of vertebrate scavengers. While there has been minimal research addressing how the biogeoclimatic conditions of Nebraska affect predicted estimates for PMI using known …
175th Commencement, Fall
Commencement Programs
Commencement program (graduate and undergraduate exercises) for Fall 2024
The Primate Gut Microbiota Contributes To Interspecific Differences In Host Metabolism., Elizabeth K Mallott, Sahana Kuthyar, Won Lee, Derek Reiman, Hongmei Jiang, Sriram Chitta, E Alexandria Waters, Brian T Layden, Ronen Sumagin, Laura D Manzanares, Guan-Yu Yang, Maria Luisa Savo Sardaro, Stanton Gray, Lawrence E Williams, Yang Dai, James P Curley, Chad R Haney, Emma R Liechty, Christopher W Kuzawa, Katherine R Amato
The Primate Gut Microbiota Contributes To Interspecific Differences In Host Metabolism., Elizabeth K Mallott, Sahana Kuthyar, Won Lee, Derek Reiman, Hongmei Jiang, Sriram Chitta, E Alexandria Waters, Brian T Layden, Ronen Sumagin, Laura D Manzanares, Guan-Yu Yang, Maria Luisa Savo Sardaro, Stanton Gray, Lawrence E Williams, Yang Dai, James P Curley, Chad R Haney, Emma R Liechty, Christopher W Kuzawa, Katherine R Amato
Faculty Research 2024
Because large brains are energetically expensive, they are associated with metabolic traits that facilitate energy availability across vertebrates. However, the biological underpinnings driving these traits are not known. Given its role in regulating host metabolism in disease studies, we hypothesized that the gut microbiome contributes to variation in normal cross-vertebrate species differences in metabolism, including those associated with the brain's energetic requirements. By inoculating germ-free mice with the gut microbiota (GM) of three primate species - two with relatively larger brains and one with a smaller brain - we demonstrated that the GM of larger-brained primates shifts host metabolism towards …